MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Bis(2,4,6-trichlorophenyl) oxalate | Bis(2,4,6-trichlorophenyl) oxalate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 1165-91-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W042438. |  |
| Bis[2-(4-hydroxyphenylthio)ethoxy]methane | Bis[2-(4-hydroxyphenylthio) ethoxy]methane (DD-70) is a Bisphenol A (BPA) replacement compound. Bis[2-(4-hydroxyphenylthio) ethoxy]methane is cytotoxic and changes the expression of genes related to xenobiotic metabolism, bile acid, and cholesterol regulation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DD-70. CAS No. 93589-69-6. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-W744923. | |
| Bis(2-bromoethyl) ether | Bis2-bromoethyl ether is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5414-19-7. Pack Sizes: 25 g; 50 g; 100 g; 250 g; 500 g; 1 k g. Product ID: HY-W013458. | |
| Bis(2-cyanoethyl) diisopropylphosphoramidite | Bis(2-cyanoethyl) diisopropylphosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides. Uses: Scientific research. Category: Signaling pathways. CAS No. 102690-88-0. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 100 g. Product ID: HY-24126. | |
| Bis(4-nitrophenyl) phosphate | Bis(4-nitrophenyl) phosphate is a catalyst for metal micelles and can catalyze the hydrolysis of (4-nitrophenyl) phosphate. Bis(4-nitrophenyl) phosphate is also an effective catalyst for ring-opening polymerization (ROP), which can achieve controlled polymerization of β-butyrolactone (β-BL) ring-opening and can be used to prepare diembedded polymers without quenching. segment copolymer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 645-15-8. Pack Sizes: 250 mg; 500 mg; 1 g. Product ID: HY-W013205. | |
| Bis(7)-tacrine dihydrochloride | Bis(7)-tacrine dihydrochloride is a dimeric AChE inhibitor derived from tacrine. Bis(7)-tacrine dihydrochloride prevents glutamate-induced neuronal apoptosis by blocking NMDA receptors. Bis(7)-tacrine dihydrochloride is a potent GABAAreceptor antagonist. Bis(7)-tacrine dihydrochloride has the potential for the research of Alzheimer's disease [1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 224445-12-9. Pack Sizes: 5 mg. Product ID: HY-120970. | |
| Bisabolene (mixture of isomers) | Bisabolene (mixture of isomers) (Bisabolene) is a sesquiterpenoid plant natural product and also a hydrocarbon precursor for various industry-relevant chemicals. Bisabolene (mixture of isomers) serves as an important precursor for the production of industry-relevant chemicals such as biofuels, bioplastics, pharmaceuticals and cosmetics[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bisabolene; γ-Bisabolene. CAS No. 495-62-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-121262. | |
| Bis(acetonitrile)palladium(II) dichloride | Bis(acetonitrile)palladium(II) dichloride is a coordination compound commonly used in organic synthesis and catalysis. Uses: Scientific research. Category: Signaling pathways. CAS No. 14592-56-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W002087. | |
| Bisacodyl | Bisacodyl is a stimulant laxative agent that works directly on the colon to produce a bowel movement. Bisacodyl increases the secretion of PGE2 by direct activation of colon macrophages. PGE2 acts as a paracrine factor and decreases the expression of AQP3 in the colon, which inhibits water transfer from the luminal to the vascular side and leads to a laxative effect[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 603-50-9. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 5 g; 10 g; 25 g; 50 g. Product ID: HY-B0557. | |
| Bis-aminooxy-PEG1 | Bis-aminooxy-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 93460-33-4. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-140407. | |
| Bis-aminooxy-PEG3 | Bis-aminooxy-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 98627-70-4. Pack Sizes: 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-140409. | |
| Bis-ANS dipotassium | Bis-ANS dipotassium is a fluorescent probe of hydrophobic protein. Bis-ANS binds to tubulin with a Kd of 2 μM[1]. Bis-ANS dipotassium is a potent biphasic modulator of protein liquid-liquid phase separation (LLPS). Bis-ANS dipotassium promotes LLPS at low concentrations but suppresses LLPS at high concentrations[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 65664-81-5. Pack Sizes: 1 mg. Product ID: HY-129811. | |
| Bisantrene | Bisantrene is a highly effective antitumor agent, it exerts its cytotoxicity by affecting DNA intercalation. Bisantrene targets eukaryotic type II topoisomerases. Bisantrene is a substrate of MDR1[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CL216942. CAS No. 78186-34-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100875. | |
| Bisantrene dihydrochloride | Bisantrene dihydrochloride is a highly effective antitumor agent, it exerts its cytotoxicity by affecting DNA intercalation. Bisantrene dihydrochloride targets eukaryotic type II topoisomerases. Bisantrene dihydrochloride is a substrate of MDR1[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CL-216942 dihydrochloride. CAS No. 71439-68-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100875A. | |
| Bis(benzo-15-crown-5) | Bis(benzo-15-crown-5) (Bis[(benzo-15-crowN-5)-4-methyl]pimelate) is a biochemical assay reagent, and can be used for chemical synthesis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bis[(benzo-15-crowN-5)-4-methyl]pimelate. CAS No. 69271-98-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157924. | |
| Bis(dibenzylideneacetone)palladium | Bis(dibenzylideneacetone)palladium is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 32005-36-0. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-W001137. | |
| Bisindolylmaleimide I | Bisindolylmaleimide I (GF109203X) is a cell-permeable and reversible PKC inhibitor (IC50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ. Bisindolylmaleimide I is also a GSK-3 inhibitor[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GF109203X; Go 6850. CAS No. 133052-90-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13867. | |
| Bisindolylmaleimide I hydrochloride | Bisindolylmaleimide I (GF109203X) hydrochloride is a cell-permeable and reversible PKC inhibitor (IC50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ. Bisindolylmaleimide I hydrochloride is also a GSK-3 inhibitor[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GF109203X hydrochloride; Go 6850 hydrochloride. CAS No. 176504-36-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13867A. | |
| Bisindolylmaleimide II | Bisindolylmaleimide II is a general inhibitor of all PKC subtypes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bis II. CAS No. 137592-45-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108604. | |
| Bisindolylmaleimide I (Standard) | Bisindolylmaleimide I (Standard) is the analytical standard of Bisindolylmaleimide I. This product is intended for research and analytical applications. Bisindolylmaleimide I (GF109203X) is a cell-permeable and reversible PKC inhibitor (IC50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ. Bisindolylmaleimide I is also a GSK-3 inhibitor[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GF109203X (Standard); Go 6850 (Standard). CAS No. 133052-90-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13867R. | |
| Bisindolylmaleimide VIII acetate | Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective protein kinase C (PKC) inhibitor with an IC50 of 158 nM for rat brain PKC. Bisindolylmaleimide VIII acetate has IC50s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, PKC-ε, respectively[1]. Bisindolylmaleimide VIII acetate facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 31-7549 acetate; Bis VIII acetate. CAS No. 138516-31-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-129624A. | |
| Bisindolylmaleimide X hydrochloride | Bisindolylmaleimide X hydrochloride(Ro 31-8425 hydrochloride, BIM-X hydrochloride) is a cell-penetrating PKC inhibitor. Bisindolylmaleimide X hydrochloride is a potent cyclin-dependent kinase 2 (CDK2) antagonist with an IC50 of 200 nM. Bisindolylmaleimide X hydrochloride inhibits the proliferation of CD4 T cells in vitro. Bisindolylmaleimide X hydrochloride inhibits eNOS-Ser1177 phosphorylation in human embryonic vein endothelial cells. Bisindolylmaleimide X hydrochloride can be used for research on the immune system and cardiovascular diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIM-X hydrochloride; Ro31-8425 hydrochloride. CAS No. 145317-11-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108136A. | |
| Bisindolylmaleimide XI hydrochloride | Bisindolylmaleimide XI hydrochloride (Ro 32-0432) is a potent, selective and orally active PKC inhibitor with IC50s of 9 nM, 28 nM, 31 nM, 37 nM, and 108 nM for PKCα, PKCβI, PKCβII, PKCγ, and PKCε, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 32-0432; Ro 31-8830 hydrochloride. CAS No. 145333-02-4. Pack Sizes: 1 mg. Product ID: HY-117610A. | |
| Bisoprolol | Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker with little activity on β2-receptor. Bisoprolol has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 66722-44-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129029. | |
| Bis-PEG10-NHS ester | Bis-PEG10-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG10-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2221949-02-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-130824. | |
| Bis-PEG1-NHS ester | Bis-PEG1-NHS ester is a nonclaevable 1-unit PEG linker for antibody-agent-conjugation (ADC). Uses: Scientific research. Category: Signaling pathways. CAS No. 65869-64-9. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-130089. | |
| Bis-?PEG4-?NHS ester | Bis-PEG4-NHS ester is a crosslinking reagent and amine-reactive modulator[1][2].Bis-PEG4-NHS ester reacts with primary amine groups on liposome surfaces via amide bond formation to covalently attach dibenzylcyclooctyne groups, with a hydrophilic PEG4 spacer reducing steric hindrance for subsequent click chemistry[1].Bis-PEG4-NHS ester enables site-specific antibody coupling to liposome surfaces via copper-free strain-promoted alkyne-azide cycloaddition click chemistry without disrupting liposome structure in minimal organic solvent volumes[1].Bis-PEG4-NHS ester undergoes hydrolysis during annealing to form -COOH groups that interact with PbI and FAI to enhance perovskite structural integrity, passivate defects, and modulate nucleation kinetics to regulate crystal growth[2].Bis-PEG4-NHS ester enhances device efficiency and long-term stability when used as an antisolvent additive for p-i-n perovskite solar cells[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1314378-11-4. Pack Sizes: 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-130086. | |
| Bis-PEG4-TFP ester | Bis-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1446282-42-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W190728. | |
| Bis-PEG6-NHS ester | Bis-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1526718-98-8. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-130410. | |
| Bis-PEG9-NHS ester | Bis-PEG9-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG9-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1008402-79-6. Pack Sizes: 25 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-117009. | |
| Bisphenol A | Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cancers, cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[1][2][3][4][5][6][7][8][9]. Uses: Scientific research. Category: Signaling pathways. CAS No. 80-05-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-18260. | |
| Bisphenol A-β-D-glucuronide | Bisphenol A-β-D-glucuronide is an inactive metabolite of the plasticizer Bisphenol A (HY-18260)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 267244-08-6. Pack Sizes: 1 mg. Product ID: HY-W585982. | |
| Bisphenol A-d16 | Bisphenol A-d16 is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 96210-87-6. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18260S. | |
| Bis(pinacolato)diborane | Bis(pinacolato)diborane is an organoboron reagent.-Bis(pinacolato)diborane serves as a source of the [Bpin] moiety with pronounced nucleophilic character and is used in the synthesis of various organoboranes, including organoboron compounds and arylboronates[1][2][3].Bis(pinacolato)diborane reacts with p-benzyne to produce tetraborylated products through a series of steps involving addition and 1,2-migration of the boryl group[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 73183-34-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 100 g; 500 g. Product ID: HY-79444. | |
| Bis-sulfone NHS ester | Bis-sulfone NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. Uses: Scientific research. Category: Signaling pathways. CAS No. 899452-51-8. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-W615327. | |
| Bis-sulfone-(PEG24)-Glu-Val-Cit-PAB-MMAE | Bis-sulfone-(PEG24)-Glu-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. Bis-sulfone-(PEG24)-Glu-Val-Cit-PAB-MMAE contains a linker and bioactive small molecule toxins MMAE (HY-15162). Bis-sulfone-(PEG24)-Glu-Val-Cit-PAB-MMAE can conjugate with NN2101 (HY-P991293) (anti c-Kit) for synthesizing NN3201. NN3201 rapidly internalizes and inhibits SCF-driven signaling, thereby delivering its payload to induce cell cycle arrest and apoptosis. NN3201 exhibits significant c-Kit-dependent anti-tumor efficacies in various tumor models, such as small cell lung cancer (SCLC) and gastrointestinal stromal tumor (GIST)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3103526-19-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-178219. | |
| Bis-sulfone-PEG3-Azide | Bis-sulfone-PEG3-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Bis-sulfone-PEG3-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1802908-01-5. Pack Sizes: 5 mg. Product ID: HY-138745. | |
| Bis-Tris | Bis-Tris is an amine buffer suitable for protein and nucleic acid systems with a pH buffer range of 5.8-7.2. Bis-Tris can also be mixed with HEPES and cacodylic acid buffer to create a pH 8 environment and monitor fluorescence emission intensity at 305 nm. Gels formulated with Bis-Tris also avoid protein degradation in samples prepared at higher pH (pH 8.5)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6976-37-0. Pack Sizes: 10 mM * 1 mL in Water; 25 g; 50 g. Product ID: HY-D0856. | |
| Bis(tri-tert-butylphosphine)palladium(0) | Bis(tri-tert-butylphosphine)palladium(0) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 53199-31-8. Pack Sizes: 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W010772. | |
| Bithionol | Bithionol is an antibacterial, anthelmintic, and algaecide agent. Bithionol is also a potent inhibitor of soluble adenylyl cyclase through binding to the allosteric activator site (IC50: 4 μM)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 97-18-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg. Product ID: HY-17592. | |
| Bitolterol mesylate | Bitolterol mesylate (WIN 37284) is a diester-type agonist amine bronchodilator without significant cardiac side effects[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Win 32784; Bitolterol methanesulfonate; S-1540 mesylate. CAS No. 30392-41-7. Pack Sizes: 5 mg. Product ID: HY-16103. | |
| Bitopertin | Bitopertin is a potent, noncompetitive glycine reuptake inhibitor, inhibits glycine uptake at human GlyT1 with a concentration exhibiting IC50 of 25 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RG1678; RO4917838. CAS No. 845614-11-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10809. | |
| Bivalirudin | Bivalirudin, a hirudin analog and anticoagulant, is a direct thrombin inhibitor. Bivalirudin inhibits thrombin-mediated fibrinogen cleavage, coagulation factor activation, and platelet activation by reversibly binding to thrombin. In addition, Bivalirudin also has certain effects of anti-virus, anti-inflammation, and vascular endothelial barrier function protection. Bivalirudin can be used for the research of thrombotic diseases and others[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 128270-60-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1929. | |
| Bivalirudin TFA | Bivalirudin TFA, a hirudin analog and anticoagulant, is a direct thrombin inhibitor. Bivalirudin TFA inhibits thrombin-mediated fibrinogen cleavage, coagulation factor activation, and platelet activation by reversibly binding to thrombin. In addition, Bivalirudin TFA also has certain effects of anti-virus, anti-inflammation, and vascular endothelial barrier function protection. Bivalirudin TFA can be used for the research of thrombotic diseases and others[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1191386-55-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15664. | |
| Bivamelagon | Bivamelagon (MC-4R Agonist 2) is an orally active MC4R agonist with EC50 values of 0.562 nM (Luci assay) and 36.5 nM (cAMP assay), and a Ki of 65 nM. Bivamelagon can be used for the research of diseases such as obesity and diabetes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MC-4R Agonist 2. CAS No. 2641595-54-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-153660. | |
| Bivatuzumab | Bivatuzumab (Anti-CD44 Recombinant Antibody; BIWA 4) is a humanized monoclonal antibody directed against CD44v6. CD44v6 could acts as a sarcoma target for CAR-redirected CIK cells[1]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: BIWA 4; Anti-CD44 Recombinant Antibody. CAS No. 214559-60-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99281. | |
| BIX-01294 | BIX-01294 is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 μM and 0.9 μM, respectively. BIX-01294 inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 has antitumor activity in recurrent tumor cells[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 935693-62-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-10587. | |
| BIX-01294 trihydrochloride | BIX-01294 trihydrochloride is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 μM and 0.9 μM, respectively. BIX-01294 trihydrochloride inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294 trihydrochloride, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 trihydrochloride has antitumor activity in recurrent tumor cells[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1392399-03-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-108239. | |
| BIX02188 | BIX02188 is a potent MEK5-selective inhibitor with an IC50 of 4.3 nM. BIX02188 inhibits ERK5 catalytic activity, with an IC50 of 810 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 334949-59-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12055. | |
| BIX02189 | BIX02189 is a potent and selective MEK5 inhibitor with an IC50 of 1.5 nM. BIX02189 also inhibits ERK5 catalytic activity with an IC50 of 59 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1265916-41-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12056. | |
| Bixafen | Bixafen, a member of the pyrazole class of fungicides, serves as a broad-spectrum agent for controlling pathogens in cereal crops by functioning as a succinate dehydrogenase inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 581809-46-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133726. | |
| Bixin | Bixin is an orally active carotenoid found in the seeds of Bixa orellana. Bixin induces apoptosis in cancer cells. Bixin possessing anti-inflammatory, anti-tumor and anti-oxidant activities. Bixin treatment ameliorated cardiac dysfunction through inhibiting fibrosis, inflammation and reactive oxygen species (ROS) generation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6983-79-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N6884. | |
| BJE6-106 | BJE6-106 (B106) is a potent, selective 3rd generation PKCδ inhibitor with an IC50 of 0.05 μM and targets selectivity over classical PKC isozyme PKCα (IC50=50 μM). BJE6-106 (B106) induces caspase-dependent apoptosis. BJE6-106 (B106) possesses tumor-specific effect. Uses: Scientific research. Category: Signaling pathways. Alternative Names: B106. CAS No. 1564249-38-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-117800. | |
| BKI-1369 | BKI-1369 is a bumped kinase inhibitor (BKI). BKI-1369 increases human Ether-a-go-go-related gene (hERG)-inhibitory activity with an IC50 of 1.52 μM. BKI-1369 reduces the parasite burden and diseases severity in the gnotobiotic pig model. BKI-1369 has been well characterized for potency, stability, metabolism, toxicity, pharmacokinetics and is potent against C. parvum in infected mice and calves[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1951431-22-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-121495. | |
| BKIDC-1553 | BKIDC-1553 is an orally active antiglycolytic agent and a bumped kinase inhibitor derived compound with a predicted ~17 h half-life in human. BKIDC-1553 inhibits CYP2C8 and Angiotensin Converting Enzyme and can be used for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1951431-34-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163438. | |
| BL-1249 | BL-1249 is a nonsteroidal anti-inflammatory agent (NSAID) and a potassium channel activator. BL-1249 potently activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2) with EC50 values of 5.5 μM and 8.0 μM, respectively. BL-1249 extracellular application activates all TREK subfamily members but has no effect on other K2P subfamilies. BL-1249 exhibits more selective for the bladder (EC50 of 1.26 μM) than vascular tissue (EC50 of 21.0 μM)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18200-13-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108596. | |
| BL-918 | BL-918 is an orally active UNC-51-like kinase 1 (ULK1) activator with an EC50 of 24.14 nM. BL-918 exerts its cytoprotective autophagic effect by targeting ULK complex. BL-918 has the potential for Parkinsons disease (PD) treatment[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2101517-69-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124729. | |
| Black pepper oleoresin | Black pepper oleoresin is a substance extracted from the pepper plant (Piper nigrum), which has aroma, spiciness, and bioactive components. It is widely used in food, health products, cosmetics, and daily chemical products. Uses: Scientific research. Category: Signaling pathways. CAS No. 84929-41-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-204591. | |
| Blarcamesine | Blarcamesine is an orally bioavailable Sigma-1 receptor agonist and muscarinic receptor modulator, with anticonvulsant, anti-amnesic, neuroprotective and antidepressant properties. Blarcamesine ameliorates neurologic impairments in a mouse model of Rett syndrome[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 195615-83-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105296. | |
| Blarcamesine hydrochloride | Blarcamesine hydrochloride (Anavex 2-73) is a Sigma-1 Receptor agonist with an IC50 of 860 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anavex 2-73. CAS No. 195615-84-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-101864. | |
| Blasticidin A | Blasticidin A ((+)-Blasticidin A) is a tetraamide acid derivative antibiotic produced by Streptomyces griseochromogenes, as well as a selective inhibitor of aflatoxin production. Blasticidin A exhibits antimicrobial activity against yeast. Blasticidin A can be used in research related to aflatoxin contamination (infection by Aspergillus sp.)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-Blasticidin A. CAS No. 100513-53-9. Pack Sizes: 1 mg. Product ID: HY-113542. | |
| Blebbistatin | Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor, promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing, and better preserves cell junctional integrity and barrier function. Blebbistatin blocks cell migration[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 674289-55-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13813. | |
| (-)-Blebbistatin | (-)-Blebbistatin is a selective inhibitor of the ATPase activity of non-muscle myosin II[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 856925-71-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13441. | |
| (+)-Blebbistatin | (+)-Blebbistatin is the inactive enantiomer of (-)-Blebbistatin. (-)-Blebbistatin is a selective inhibitor of myosin II ATPase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1177356-70-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107657. | |
| Bleomycin A5 | Bleomycin A5 (Pingyangmycin) is a glycopeptide antibiotic with multiple biological activities, which can be isolated from Streptomyces. Bleomycin A5 exerts cytotoxic effects by binding to Fe2+ to form a complex, inducing single-strand and double-strand DNA breaks, and inhibiting DNA replication. Bleomycin A5 inhibits Drp1-mediated mitochondrial fission and suppresses PINK1/Parkin pathway-mediated mitophagy, ultimately triggering mitochondria-mediated cellular apoptosis. Bleomycin A5 can be used in cancer research[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pingyangmycin. CAS No. 11116-32-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N10470. | |
| Bleomycin B4 | Bleomycin B4 (Phleomycin F) is an antibiotic. Bleomycin B4 has antitumor activity. Bleomycin B4 can be used for the research of cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Phleomycin F. CAS No. 9060-11-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N10469. | |
| Bleomycin hydrochloride | Bleomycin hydrochloride is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin hydrochloride is an antitumor antibiotic[1]. Uses: Scientific research. Category: Induced disease models products. CAS No. 67763-87-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17565A. | |
| Bleomycin sulfate | Bleomycin sulfate is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin sulfate is an antitumor antibiotic[1]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Bleomycin sulfate. CAS No. 9041-93-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-17565. | |
| Bleselumab | Bleselumab (ASKP 1240) is a human anti-CD40 monoclonal antibody (mAb). Bleselumab binds to human CD40 with high affinity (Kd: 0.24 nM). Bleselumab inhibits immune responses by blocking the interaction of CD40 with its ligand CD40L. Bleselumab prevents organ transplant rejection[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASKP 1240. CAS No. 1453067-91-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99257. | |
| Bletilloside A | Bletilloside A is a glycoside. Bletilloside A can be isolated from the tubers of Bletilla striata. Bletilloside A inhibits the expression of the TCL1A protein. When evaluated for its inhibitory activity against LPS-induced NO, Bletilloside A shows an IC50 of >70 μM. Bletilloside A exhibits anticancer activity against acute myeloid leukemia. Bletilloside A can be used in studies related to acute myeloid leukemia[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2292159-89-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N8177. | |
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