MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Calcein Blue AM | Calcein Blue AM is a cellular dye agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 168482-84-6. Pack Sizes: 1 mg (2.15 mM * 1 mL in DMSO). Product ID: HY-124298. |  |
| Calcifediol | Calcifediol (25-hydroxy Vitamin D3) is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels[1][2][3]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: 25-Hydroxy Vitamin D3. CAS No. 19356-17-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-32351. | |
| Calcifediol-d6 | Calcifediol-d6 is the deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR ligand[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 25-hydroxy Vitamin D3-d6. CAS No. 78782-98-6. Pack Sizes: 10 mM * 1 mL in DMSO; 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13332. | |
| Calcifediol monohydrate | Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 25-hydroxy Vitamin D3 monohydrate. CAS No. 63283-36-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-32351A. | |
| Calcimycin | Calcimycin (A-23187) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin induces apoptosis and autophagy[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: A-23187; Antibiotic A-23187. CAS No. 52665-69-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-N6687. | |
| Calcipotriol | Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MC 903; Calcipotriene. CAS No. 112965-21-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10001. | |
| Calcipotriol Impurity C | Calcipotriol Impurity C is the impurity of Calcipotriol, Calcipotriol is a ligand of VDR-like receptors. Uses: Scientific research. Category: Signaling pathways. CAS No. 113082-99-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-75035. | |
| Calcipotriol monohydrate | Calcipotriol monohydrate is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor. Uses: Scientific research. Category: Signaling pathways. CAS No. 147657-22-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10001A. | |
| Calcitetrol | Calcitetrol (1α, 24, 25-Trihydroxy VD3), a Vitamin D3 (HY-15398) metabolite, is the hormonally active form of vitamin D. Calcitetrol participates in regulation of Treg cells. Calcitetrol can be used for the research of Toxoplasma gondii infection[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1α, 24, 25-Trihydroxy VD3. CAS No. 72203-93-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-15157. | |
| Calcitonin (8-32), salmon | Calcitonin (8-32), salmon is a highly selective Amylin receptor antagonist. Calcitonin (8-32), salmon reverses the Amylin-mediated inhibition of glucose-induced insulin release, but has no effect on either glucagon release or somatostatin release. Calcitonin (8-32), salmon can be used for studies related to β-cell amylin[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 155069-90-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1782. | |
| Calcitonin (human) | Calcitonin (human) is a hypocalcemic hormone. Calcitonin can lower blood calcium levels and inhibit bone resorption. Calcitonin can be used in hypercalcemia or osteoporosis research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 21215-62-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2273. | |
| Calcitonin (rat) | Calcitonin (rat) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1]. Uses: Scientific research. Category: Peptides. CAS No. 11118-25-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P4973. | |
| Calcitonin (salmon) | Calcitonin salmon, a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Salmon calcitonin. CAS No. 47931-85-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0090. | |
| Calcitriol | Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,25-Dihydroxyvitamin D3. CAS No. 32222-06-3. Pack Sizes: 1 mg; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10002. | |
| Calcitriol-d6 | Calcitriol-d6 is the deuterium labeled Calcitriol. Calcitriol is the active metabolite of vitamin D3 and an agonist of the vitamin D receptor (VDR)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 78782-99-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-76814. | |
| Calcitriol (Standard) | Calcitriol (Standard) is the analytical standard of Calcitriol. This product is intended for research and analytical applications. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,25-Dihydroxyvitamin D3 (Standard). CAS No. 32222-06-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10002R. | |
| Calcium chloride anhydrous, for cell culture | Calcium chloride anhydrous, for cell culture is an inorganic salt for the preparation of various buffers[1]. Calcium chloride anhydrous, for cell culture can be used for animal modeling, to construct abdominal aortic aneurysm models[3]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Calcium dichloride anhydrous, for cell culture. CAS No. 10043-52-4. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-Y0406E. | |
| Calcium chloride anhydrous, powder, 97% | Calcium chloride anhydrous, powder, 97% is an inorganic salt for the preparation of various buffers[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Calcium dichloride anhydrous, powder, 97%. CAS No. 10043-52-4. Pack Sizes: 100 g; 500 g; 1 k g. Product ID: HY-Y0406H. | |
| Calcium chloride dihydrate, for cell culture, 99% | Calcium chloride dihydrate, for cell culture, 99% is a biochemical reagent. Calcium chloride dihydrate, for cell culture, 99% enhances the dentinogenic differentiation potential of WMTA on cells. Calcium chloride dihydrate, for cell culture, 99% can be used as a biological material or organic compound for life science related research[1][2. Uses: Scientific research. Category: Signaling pathways. CAS No. 10035-04-8. Pack Sizes: 25 g. Product ID: HY-108536D. | |
| Calcium Green 1AM | Calcium Green 1AM is a cell-permeant fluorescent calcium indicator (Excitation 506 nm; Emission 531 nm). Calcium Green 1AM is converted to the fluorescent calcium indicator by intracellular esterases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 186501-28-0. Pack Sizes: 50 μg. Product ID: HY-D1176. | |
| Calcium Orange AM | Calcium Orange AM is an intracellular calcium reporter. Specific fluorescence can be detected when free calcium binds to Calcium Orange AM (Ex/Em=549/576 nm). Calcium Orange AM does not enter the vacuoles and does not compartmentalize into acidic vesicles[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 172646-19-4. Pack Sizes: 50 μg. Product ID: HY-D1629. | |
| Calcium phosphate monobasic monohydrate | Calcium phosphate monobasic monohydrate (Calcium superphosphate) is a kind of biological materials or organic compounds that are widely used in life science research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Calcium superphosphate. CAS No. 10031-30-8. Pack Sizes: 50 g; 100 g; 500 g; 1 k g. Product ID: HY-W094707. | |
| Calcium phosphorylcholine-d9 chloride | Calcium phosphorylcholine-d9 (chloride) is the deuterium labeled Calcium phosphorylcholine chloride. Calcium phosphorylcholine chloride is the main phospholipid component in eukaryotic biofilms. Calcium phosphorylcholine chloride exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Calcium phosphorylcholine chloride exhibits a surprising range of immunomodulatory properties[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Phosphocholine-d9 chloride calcium. CAS No. 344299-43-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B2233AS. | |
| Calcium polystyrene sulfonate | Calcium polystyrene sulfonate (Poly(styrenesulfonic acid) calcium salt) is an orally active potassium-lowering agent. Calcium polystyrene sulfonate binds potassium in the distal colon in exchange for Ca2+. Calcium polystyrene sulfonate can be used for the research of hyperkalemia in chronic kidney disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Poly(styrenesulfonic acid) calcium salt. CAS No. 37286-92-3. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-107929. | |
| Calderasib | Calderasib (MK-1084) is a selective KRAS G12C inhibitor. Calderasib exhibits anticancer activity and can be used either alone or in combination with Pembrolizumab (HY-P9902) for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-1084. CAS No. 2641216-67-1. Pack Sizes: 10 mM * 1 mL in DMSO; 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162431. | |
| Calenduloside E | Calenduloside E is a pentacyclic triterpenoid saponin that can be extracted from the bark and roots of Aralia ovata, and has anti-inflammatory and anti-apoptotic activities. Calenduloside E alleviates atherosclerosis by regulating macrophage polarization, improves mitochondrial function by regulating the AMPK-SIRT3 pathway, and alleviates acute liver injury. In addition, Calenduloside E promotes the interaction between L-type calcium channels and Bcl-2 related apoptosis genes, inhibits calcium overload, and alleviates myocardial ischemia/reperfusion injury. Calenduloside E also improves non-alcoholic fatty liver disease by regulating heat shock-dependent pathways, and inhibits ROS mediated JAK1-STAT3 pathways to reduce cellular inflammatory responses[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 26020-14-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N6850. | |
| CalFluor 488 Azide | CalFluor 488 Azide is a water-soluble fluorogenic azide probe. CalFluor 488 Azide is activated by Cu-catalyzed or metal-free click reaction. CalFluor 488 Azide is not fluorescent until it is reacted with alkynes[1][2]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1798305-98-2. Pack Sizes: 1 mg. Product ID: HY-151708. | |
| Calf thymus DNA | Calf thymus DNA (DNA from calf thymus) is high quality double-stranded template DNA isolated from the thymus of male and female calves. Calf thymus DNA can be used for the research of the interaction between DNA and agents[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DNA from calf thymus, Thymonucleic acid. CAS No. 91080-16-9. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109517. | |
| Calhex 231 hydrochloride | Calhex 231 hydrochloride is a potent negative allosteric modulator that blocks (IC50 = 0.39 μM) increases in [3H]inositol phosphates elicited by activating the human wild-type CaSR transiently Ca2+-sensing receptor. Calhex 231 hydrochloride can be used in the study of traumatic hemorrhagic shock (THS) and diabetic cardiomyopathy (DCM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2387505-78-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103320A. | |
| Calicheamicin | Calicheamicin, an antitumor antibiotic, is a cytotoxic agent that causes double-strand DNA breaks. Calicheamicin is a DNA synthesis inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Calicheamicin γ1. CAS No. 108212-75-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19609. | |
| Callistephin chloride | Callistephin (Pelargonidin 3-O-glucoside) chloride is an anthocyanin. Callistephin chloride regulates the expression of inflammatory (reducing iNOS/TNF-α/COX-2) and apoptosis-related proteins by inhibiting p38 phosphorylation, and enhances the protective effect of Isoflurane (HY-A0134) on microglial cell damage. Callistephin chloride significantly reduces ROS levels, eliminates DPPH free radicals, protects retinal pigment epithelial cells, and inhibits lipid peroxidation. Callistephin chloride can alleviate glutamate excitotoxicity, reduce neuronal apoptosis, and protect cerebellar granule neurons. Callistephin chloride can inhibit the proliferation and metastasis of breast cancer cells by inducing apoptosis[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pelargonidin-3-O-glucoside chloride. CAS No. 18466-51-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-W040045. | |
| Calmidazolium chloride | Calmidazolium chloride (R 24571) is a calmodulin antagonist, antagonizing CaM-dependent phosphodiesterase and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase with IC50s of 0.15 and 0.35 μM, respectively[1]. Also in anti-cancer research[2]. Calmidazolium binds to calmodulin with a Kd of 3 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R 24571. CAS No. 57265-65-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-103319. | |
| Calotatug ginistinag | Calotatug ginistinag (XMT-2056) is an antibody-drug conjugate targeting HER2, with an effective payload connected via a linker (LP, HY-148067) to a STING agonist (STING agonist-20, HY-148068), and has potential immune activation and anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XMT-2056. CAS No. 2847102-44-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164919. | |
| Caloxin 2A1 | Caloxin 2A1 is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor. Caloxin 2A1 does not affect basal Mg2+-ATPase or Na+-K+-ATPase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 350670-85-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3278. | |
| Calpain-2-IN-1 | Calpain-2-IN-1 (Formula 1A) is a isoform-specific calpain-2 inhibitor with Kis of 181 nM and 7.8 nM for calpain-1, and calpain-2, respectively. Calpain-2-IN-1 can be used for the research of neurodegenerative diseases and other diseases of synaptic function[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 144231-85-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145155. | |
| Calpeptin | Calpeptin is a potent, cell penetrating calpain inhibitor, with an ID50 of 40 nM for Calpain I in human platelets[1]. Calpeptin is also an inhibitor of cathepsin K[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 117591-20-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100223. | |
| Calphostin C | Calphostin C is a highly selective PKC inhibitor (IC50=0.05 μM) and tumor apoptosis inducer. Calphostin C competitively binds to PKC and inhibits PKC-mediated phosphorylation signal transduction. Calphostin C restores Na+/K+ ATPase activity in the sciatic nerve of diabetic mice and improves neuropathy. Calphostin C can be used in the study of anti-tumor and diabetic complications[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: UCN-1028C. CAS No. 121263-19-2. Pack Sizes: 100 μg. Product ID: HY-105416. | |
| Calpurbatug | Calpurbatug is an immunoglobulin G1 antibody. Calpurbatug has activity with anti-bacterial DNA-binding protein DNABII family and anti-human monoclonal TRL1068 γ1-chain[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TRL1068. CAS No. 2635404-72-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990021. | |
| Calycosin | Calycosin is a compound that can be isolated from Radix Astragali. Calycosin has strong antioxidant, anti-inflammatory and apoptosis-modulating effects. Calycosin can be used for the research of ovarian cancer and breast cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cyclosin. CAS No. 20575-57-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0519. | |
| Calyculin A | Calyculin A ((-)-Calyculin A) is a potent and cell-permeable protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) inhibitor with IC50s of 2 nM and 0.5-1 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Calyculin A. CAS No. 101932-71-2. Pack Sizes: 10 μg. Product ID: HY-18983. | |
| CAM2602 | CAM2602 is an orally active Aurora A-TPX2 protein-protein interaction inhibitor with a human Kd of 19 nM for Aurora A. CAM2602 increases the proportion of PH3 positive cells while reducing P-T288 Aurora A levels. CAM2602 arrests tumor xenograft growth in mice. CAM2602 can be used for the research of cancer, such as acute T cell leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3056388-47-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-168022. | |
| CAM833 | CAM833 is a potent orthosteric inhibitor of the interaction between BRCA2 and RAD51 with a Kd of 366 nM against the ChimRAD51 protein. CAM833 also inhibits RAD51 oligomerization. CAM833 increases the progression of G2/M-arrested cells into apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2758364-02-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150147. | |
| Camalexin | Camalexin is a phytoalexin isolated from Camelina sativa (Cruciferae) with antibacterial, antifungal, antiproliferative and anticancer activities. Camalexin can induce reactive oxygen species (ROS) production[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 135531-86-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-119502. | |
| Cambinol | Cambinol is a SIRT1 and SIRT2 inhibitor with IC50 values of 56 μM and 59 μM, respectively. Cambinol is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 14513-15-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100732. | |
| Camibirstat | FHD-286 is a selective, oral inhibitor of SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor. FHD-286 has the potential for the research of BAF (BRG1/BRM-associated factor)-related disorders such as acute myeloid leukemia[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FHD-286. CAS No. 2671128-05-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-144835. | |
| Camidanlumab | Camidanlumab (HuMax-TAC) is a humanized IgG1 monoclonal antibody against CD25. Camidanlumab can be used to synthesize the ADC molecule Camidanlumab tesirine (HY-141599). Camidanlumab can be used in the research of tumors such as lymphoma and leukemia. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HuMax-TAC. CAS No. 921618-45-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99233. | |
| Camidanlumab tesirine | Camidanlumab tesirine (ADCT 301) is an ADC comprising HuMax-TAC, a human IgG1 mAb directed against human CD25, stochastically conjugated through a dipeptide cleavable linker to a pyrrolobenzodiazepine (PBD) dimer warhead. Camidanlumab tesirine has a drug-antibody ratio (DAR) of 2.3. Camidanlumab tesirine binds human CD25 with picomolar affinity. Camidanlumab tesirine has highly potent and selective cytotoxicity against a panel of CD25-expressing human lymphoma cell lines[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ADCT 301. CAS No. 1853239-04-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-141599. | |
| Camizestrant | Camizestrant (AZD-9833) is a potent and orally active estrogen receptor (ER) antagonist. Camizestrant is used for the study of ER+ HER2-advanced breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD-9833. CAS No. 2222844-89-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136255. | |
| CAMK1D-IN-1 | CAMK1D-IN-1 (compound I) is an inhibitor of CAMK1D, targeting cytotoxic T lymphocyte (CTL)-resistant tumor cells. CAMK1D impairs CTL-induced death receptor signaling and apoptosis by inhibiting caspases, making it a key and effective target for PD-L1-refractory tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 404828-08-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156871. | |
| CaMKIIδ-IN-1 | CaMKIIδ-IN-1 (Compound 15e) is a pyrimidine-based inhibitor of CaMKIIδ with an IC50 of 12 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1026029-18-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-171932. | |
| CaMKII-IN-1 | CaMKII-IN-1 is a highly selective inhibitor of CaMKII with an IC50 value of 63nM. It has almost no effect on CaMKIV, MLCK, p38a, Akt1, and PKC. Uses: Scientific research. Category: Signaling pathways. CAS No. 1208123-85-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18271. | |
| CaMKK2-IN-1 | CaMKK2-IN-1 is a selective, ligand-efficient inhibitor of CaMKK2, with IC50 of 7 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3032691-65-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162009. | |
| Camlipixant | Camlipixant (BLU-5937) a potent, selective, non-competitive and orally active P2X3 homotrimeric receptor antagonist with an IC50 of 25 nM against hP2X3 homotrimeric. Camlipixant shows potent anti-tussive effect and no taste alteration. Camlipixant can be used for the research of unexplained, refractory chronic cough[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BLU-5937. CAS No. 1621164-74-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136026. | |
| Camonsertib | Camonsertib (RP-3500) is an orally active, selective ATR kinase inhibitor (ATRi) with an IC50 of 1.00 nM in biochemical assays. Camonsertib shows 30-fold selectivity for ATR over mTOR (IC50=120 nM) and >2,000-fold selectivity over ATM, DNA-PK, and PI3Kα kinases. Camonsertib has potent antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RP-3500; ATR inhibitor 4. CAS No. 2417489-10-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139609. | |
| Camostat | Camostat is an orally active trypsin inhibitor. Camostat can reduce pancreatic fibrosis induced by repeated administration of superoxide dismutase inhibitors in rats, and decrease the proliferation and activation of pancreatic stellate cells (PSCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 59721-28-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-165529. | |
| Camostat mesylate | Camostat mesylate (Camostat mesilate) is an orally active, synthetic serine protease inhibitor for chronic pancreatitis. Camostat mesylate, an inhibitor of TMPRSS2, shows antiviral activity against SARS-CoV-2. Camostat mesylate also inhibits the activity of prostasin, trypsin, and matriptase[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Camostat mesilate; FOY305; FOY-S980. CAS No. 59721-29-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13512. | |
| Camoteskimab | Camoteskimab is a fully human monoclonal antibody with high affinity targeting IL-18. Camoteskimab is applicable to the research of autoinflammatory diseases[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AVTX-007; CERC-007; MEDI 2338. CAS No. 2492472-82-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99491. | |
| Campesterol | Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects. Uses: Scientific research. Category: Signaling pathways. CAS No. 474-62-4. Pack Sizes: 10 mM * 1 mL in Ethanol; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1459. | |
| Camphor (Standard) | Camphor (Standard) is the analytical standard of Camphor. This product is intended for research and analytical applications. Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities[1]. Camphor is a TRPV3 agonist[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Camphor (Standard). CAS No. 76-22-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0808R. | |
| Camptothecin | Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM[1]. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells[2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Campathecin; (S)-(+)-Camptothecin; CPT. CAS No. 7689-3-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-16560. | |
| Camptothecin-20(S)-O-propionate | Camptothecin-20(S)-O-propionate (CZ48), the C20-propionate ester of CPT, is a highly effective anticancer agent. Camptothecin-20(S)-O-propionate (CZ48) is a topoisomerase-&Lota; inhibitor[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Camptothecin-20-O-propionate. CAS No. 194414-69-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114668. | |
| Camrelizumab | Camrelizumab (SHR-1210) is a potent humanied high-affinity IgG4-κ monoclonal antibody (mAb) to PD-1. Camrelizumab binds PD-1 at a high affinity of 3 nM and inhibits the binding interaction of PD-1 and PD-L1 with an IC50 of 0.70 nM. Camrelizumab acts as anti-PD-1/PD-L1 agent and can be used for cancer research, including NSCLC, ESCC, Hodgkin lymphoma, and advanced HCC et,al[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SHR-1210; INCSHR1210. CAS No. 1798286-48-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9971. | |
| Camylofine | Camylofin is an antimuscarinic, is a smooth muscle relaxant. Uses: Scientific research. Category: Signaling pathways. CAS No. 54-30-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1230. | |
| Canagliflozin | Canagliflozin (JNJ 28431754) is a selective SGLT2 inhibitor with IC50s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JNJ 28431754. CAS No. 842133-18-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10451. | |
| Canagliflozin hemihydrate | Canagliflozin hemihydrate (JNJ28431754 hemihydrate) is a selective SGLT2 inhibitor with IC50s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JNJ 28431754 hemihydrate. CAS No. 928672-86-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-I0383. | |
| Canakinumab | Canakinumab (ACZ885) is a recombinant human anti-IL-1β monoclonal antibody. Canakinumab shows IC50 values of 43.6 and 40.8 pM for human and marmoset IL-1β, respectively. The mode of action of canakinumab is based on the neutralization of IL-1β signaling, resulting in suppression of inflammation related to disorders of autoimmune origin[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ilaris; ACZ 885. CAS No. 914613-48-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108810. | |
| Candesartan | Candesartan (CV 11974) is an orally active angiotensin II AT1-Receptor blocker and PPAR-γ agonist. Candesartan has potent and long-lasting antihypertensive effects. Candesartan can be used for the research of hypertension, chronic heart failure (CHF) and Traumatic brain injury (TBI)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CV 11974. CAS No. 139481-59-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0205. | |
| Candesartan Cilexetil | Candesartan Cilexetil (TCV-116) is an angiotensin II receptor inhibitor. Candesartan Cilexetil ameliorates the pulmonary fibrosis and has antiviral and skin wound healing effect. Candesartan Cilexetil can be used for the research of high blood pressure[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TCV-116. CAS No. 145040-37-5. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-17505. | |
| Candesartan-d4 | Candesartan-d4 (CV-11974-d4) is the deuterium labeled Candesartan (HY-B0205). Candesartan (CV 11974) is an orally active angiotensin II AT1-Receptor blocker and PPAR-γ agonist. Candesartan has potent and long-lasting antihypertensive effects. Candesartan can be used for the research of hypertension, chronic heart failure (CHF) and Traumatic brain injury (TBI). Uses: Scientific research. Category: Signaling pathways. Alternative Names: CV-11974-d4. CAS No. 1346604-70-3. Pack Sizes: 1 mg. Product ID: HY-B0205S. | |
| Candidalysin | Candidalysin is a cytolytic peptide toxin secreted by the fungus Candida albicans. Candidalysin drives epithelial immune responses by activating the EGFR-MAPK signaling pathway, inducing MMP expression and calcium influx, and regulating the c-Fos transcription factor and MKP1 via p38 MAPK and ERK1/2 respectively. Candidalysin is essential for mucosal and systemic infections, activating NLRP3 to promote inflammatory responses, neutrophil recruitment, and Th17 immunity. Candidalysin activates LDH causing membrane damage and exhibiting cytotoxicity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1906866-53-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10408. | |
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