MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Carfilzomib (Standard) | Carfilzomib (Standard) is the analytical standard of Carfilzomib. This product is intended for research and analytical applications. Carfilzomib (PR-171) is an irreversible proteasome inhibitor with an IC50 of 5 nM in ANBL-6 and RPMI 8226 cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PR-171 (Standard). CAS No. 868540-17-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10455R. |  |
| Cariporide | Cariporide (HOE-642) is a selective Na+/H+ exchange inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HOE-642 Free Base. CAS No. 159138-80-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19693. | |
| Cariprazine | Cariprazine is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). Uses: Scientific research. Category: Signaling pathways. Alternative Names: RGH-188. CAS No. 839712-12-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14763. | |
| Cariprazine-d6 | Cariprazine-d6 is a deuterium labeled Cariprazine. Cariprazine Cariprazine is an antipsychotic agent that exhibits high affinity for the D3 (Ki of 0.085 nM) and D2 (Ki of 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki of 2.6 nM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RGH-188-d6. CAS No. 1308278-67-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-14763S. | |
| Cariprazine-d8 | Cariprazine-d8 is a deuterium labeled Cariprazine. Cariprazine is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). Uses: Scientific research. Category: Signaling pathways. Alternative Names: RGH-188 d8. CAS No. 1308278-50-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-14763S1. | |
| Cariprazine hydrochloride | Cariprazine hydrochloride is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). Uses: Scientific research. Category: Signaling pathways. Alternative Names: RGH188 hydrochloride. CAS No. 1083076-69-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-14763A. | |
| Carlumab | Carlumab (CNTO 888) is a human anti-CCL2 (chemokine ligand 2) monoclonal antibody. Carlumab binds and neutralises profibrotic activities of human CCL2. Carlumab inhibits tumor growth by reducing macrophage infiltration and decreasing tumor microvascular density. Carlumab can be used for the research of cancer, suah as prostate cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CNTO 888. CAS No. 915404-94-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99188. | |
| CARM1-IN-1 hydrochloride | CARM1-IN-1 (compound 7g) hydrochloride is a highly potent and selective inhibitor of CARM1 (IC50=8.6 μM, CARM1/PABP1), with low inhibitory activity against PRMT1 and SET7 (IC50 >667 μM). CARM1-IN-1 hydrochloride inhibits the methylation activity of CARM1 and the methylation levels of different substrates, such as PABP1, CA150, SmB, and H3. CARM1-IN-1 hydrochloride also inhibits the promoter activity of prostate-specific antigen (PSA) without significant cytotoxicity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2070018-31-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12759A. | |
| Carminic acid | Carminic acid is a widely used and orally active natural red pigment that can be used in industries such as food, cosmetics, and pharmaceuticals. In addition, carminic acid has anti-inflammatory and antioxidant activities[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1260-17-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-N8407. | |
| Carmofur | Carmofur (HCFU) is a rat recombinant acid ceramidase inhibitor with an IC50 of 29 nM. Carmofur is also a protease inhibitor of SARS-CoV-2 main protease (Mpro), fatty acid amide hydrolase (FAAH) and N-acylethanolamine acid amidase (NAAA). Carmofur has anti-cancer, anti-inflammatory and anti-virus activities, and can be used for the study of COVID-19 and acute lung injury (ALI)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HCFU. CAS No. 61422-45-5. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0182. | |
| Carmoterol hydrochloride | Carmoterol hydrochloride is a highly potent, selective and long-acting β2-adrenoceptor agonist with the pEC50 of 10.19. Carmoterol has 53 times higher affinity for the β2-adrenoceptors than for the β1-adrenoceptors. Carmoterol hydrochloride can be used for the research of asthma and chronic obstructive pulmonary disease (COPD)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 137888-11-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12463. | |
| Carmustine | Carmustine is an antitumor chemotherapeutic agent, which works by akylating DNA and RNA. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BCNU. CAS No. 154-93-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13585. | |
| Carnitine acetyltransferase | Carnitine acetyltransferase is a mitochondrial matrix enzyme that catalyzes the interconversion of Acetyl-CoA and Acetylcarnitine (HY-126358). Carnitine acetyltransferase functions as a positive regulator of total body glucose tolerance and muscle activity of pyruvate dehydrogenase. Carnitine acetyltransferase is responsible for mitochondrial acetyl-CoA balance and regulation of fatty acid oxidation by utilizing short- and medium- chain fatty acids and their corresponding acylcarnitines as substrates. Carnitine acetyltransferase plays a crucial role in regulating glucose homeostasis. Carnitine acetyltransferase can be utilized in the research of aging, obesity, and diabetes[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9029-90-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P2914. | |
| (±)-Carnitine-d9 chloride | (±)-Carnitine-d9 (chloride) is the deuterium labeled (±)-Carnitine chloride. (±)-Carnitine chloride exists in two isomers, known as D and L. L-carnitine plays an essential role in the β-oxidation of fatty acids and also shows antioxidant, and anti-inflammatory activities. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DL-Carnitine-d9 chloride; DL-Levocarnitine-d9 chloride. CAS No. 1219386-75-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B1453S1. | |
| Carnosic acid | Carnosic acid is an orally active lipid absorption inhibitor. Carnosic acid has demonstrated inhibition of oxidative stress and inflammation, suppression of cell proliferation, and antibacterial activity. Uses: Scientific research. Category: Signaling pathways. CAS No. 3650-9-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0644. | |
| Carnosol | Carnosol is a potent Ribosomal S6 Kinase (RSK2) inhibitor that could be useful for treating gastric cancer, with an IC50 of ~5.5 μM[1]. Carnosol, a Nrf2 activator, increases the nuclear levels of Nrf2 and can promote the expression of heme oxygenase 1 (HMOX1)[2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5957-80-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0643. | |
| Carotegrast | Carotegrast (HCA2969) is an orally active α4 integrin inhibitor with anti-inflammatory activity. Carotegrast can be used in the research of inflammation-related diseases, such as ulcerative colitis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HCA2969. CAS No. 401904-75-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14857. | |
| Carotegrast methyl | Carotegrast methyl (AJM300) is an orally active and selective α4 integrin antagonist. HCA2969, an active metabolite of Carotegrast methyl, is a specific and dual α4β1/α4β7 integrin antagonist. Carotegrast methyl prevents the development of colitis in mice[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AJM300. CAS No. 401905-67-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124290. | |
| Carotuximab | Carotuximab (TRC105) is a IgG1 monoclonal antibody that blocks endoglin (CD105) and its downstream Smad signaling pathway. Carotuximab has immunomodulatory and antineoplastic actions[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TRC105; DE-122. CAS No. 1268714-50-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99494. | |
| Carperitide acetate | Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine acetate) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. Carperitide acetate inhibits endothelin-1 secretion in a dose-dependent way. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Atrial Natriuretic Peptide (ANP) (1-28), human, porcine acetate. CAS No. 1366000-58-9. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P1235A. | |
| Carprofen | Carprofen is a nonsteroid anti-inflammatory agent, acts as a multi-target FAAH/COX inhibitor, with IC50s of 3.9 μM, 22.3 μM and 78.6 μM for COX-2, COX-1 and FAAH, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 53716-49-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-B1227. | |
| CART(55-102)(human) | CART(55-102)(human) is an endogenous satiety factor with potent appetite-suppressing activity. CART(55-102)(human) is closely associated with leptin and neuropeptide Y[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 214050-22-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1304. | |
| CART(55-102)(rat) | CART(55-102)(rat) is a rat satiety factor with potent appetite-suppressing activity. CART(55-102)(rat) is closely associated with leptin and neuropeptide Y. CART(55-102)(rat) can induces anxiety and stress-related behavior[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 209615-79-2. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1305. | |
| CART(62-76)(human,rat) | CART(62-76)(human,rat) is a neuropeptide (62-76 residues of the CART peptide) with neurotransmitter-like effects. CART(62-76)(human,rat) can modulate the activity of striatal noradrenergic and corticostriatal and hypothalamic serotoninergic (5-HT) system in the rat brain[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 210978-19-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1303. | |
| Carteolol hydrochloride | Carteolol hydrochloride (OPC-1085 hydrochloride) is a non-selective beta blocker used to treat glaucoma. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OPC-1085 hydrochloride. CAS No. 51781-21-6. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-17495A. | |
| Carvacrol | Carvacrol is an orally active and blood-brain barrier-permeable monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cymophenol. CAS No. 499-75-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-N0711. | |
| Carvacrol (Standard) | Carvacrol (Standard) is the analytical standard of Carvacrol. This product is intended for research and analytical applications. Carvacrol is an orally active and blood-brain barrier-permeable monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cymophenol (Standard). CAS No. 499-75-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0711R. | |
| Carvedilol | Carvedilol (BM 14190) is a non-selective β/α-1 blocker[1]. Carvedilol inhibits lipid peroxidation in a dose-dependent manner with an IC50 of 5 μM. Carvedilol is a multiple action antihypertensive agent with potential use in angina and congestive heart failure[2]. Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BM 14190. CAS No. 72956-09-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-B0006. | |
| Carvedilol metabolite 4-Hydroxyphenyl Carvedilol | 4-Hydroxyphenyl Carvedilol, a metabolite of Carvedilol, is an active metabolite of Carvedilol (HY-B0006) and is produced via CYP2D6-mediated oxidation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Hydroxyphenyl Carvedilol; 4-Hydroxycarvedilol. CAS No. 142227-49-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-12767. | |
| Carvone | Carvone is a ketone monoterpene found in the essential oils from plants of the genus Mentha. Carvone has such effects as anticancer, antimicrobial, antioxidant, anti-inflammatory, antispasmodic, antinociceptive, anticonvulsant[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 99-49-0. Pack Sizes: 5 g; 10 g. Product ID: HY-108964. | |
| (-)-Carvone | (-)-Carvone is an insect neurotoxin and a irreversible acetylcholinesterase (AChE) inhibitor. (-)-Carvone can be used as a bird repellent, inhibits larval growth, decreases pupatation rate, and increases mortality of larvae[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6485-40-1. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 50 g; 100 g. Product ID: HY-W017423. | |
| Casdatifan | Casdatifan (AB521) is an orally active and selective allosteric small-molecule inhibitor of hypoxia-inducible factor 2α (HIF-2α). Casdatifan inhibits pro-tumor gene transcription by blocking the heterodimerization of HIF-2α with ARNT, and significantly suppresses tumor growth in clear cell renal cell carcinoma (ccRCC) models either as a monotherapy or in combination with agents such as Zimberelimab (HY-P99109). Casdatifan is applicable for the research of ccRCC[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AB521. CAS No. 2709069-30-5. Pack Sizes: 10 mM * 1 mL in DMSO; 100 μg; 500 μg; 1 mg; 2 mg; 5 mg; 10 mg. Product ID: HY-159644. | |
| Casdozokitug | Casdozokitug (SRF-388) is an IgG1κ antibody targeting IL27[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SRF-388. CAS No. 2643331-37-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990024. | |
| Casein | Casein is an orally active phosphoprotein that can be separated into various electrophoretic components, such as α2-Casein, κ-Casein, β-casein, and γ-casein. Casein has also been blended and grafted with other polymers, cross-linkers, or monomers to improve its functional properties. Casein enhances calcium absorption and reduces the extent of fissure as well as smooth-surface caries. Casein promotes proliferation of prostate cancer. Casein has various applications in the paper, leather, textile, and food industries, serving as coatings, adhesives, and packaging materials[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9000-71-9. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-125865. | |
| Casein kinase 1δ-IN-6 | Casein kinase 1δ-IN-6 is a potent and selective protein kinase CK-1δ inhibitor with an IC50 of 23 nM. Casein kinase 1δ-IN-6 shows neuroprotective and anti-inflammatory properties both in vitro and in vivo. Casein kinase 1δ-IN-6 is a promising drug candidate and can be used for neurodegenerative diseases research. Uses: Scientific research. Category: Signaling pathways. CAS No. 1579991-01-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153905. | |
| Casein Kinase inhibitor A86 | Casein Kinase inhibitor A86 is a potent and orally active casein kinase 1α (CK1α) inhibitor. Casein Kinase inhibitor A86 also inhibits of CDK7 (TFIIH) and CDK9 (P-TEFb). Casein Kinase inhibitor A861 induces leukemia cell apoptosis, and has potent anti-leukemic activities[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2079069-01-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123955. | |
| CASIN | CASIN is a selective GTPase Cdc42 inhibitor with an IC50 of 2 uM. CASIN can be used for the research of cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 425399-05-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12874. | |
| Casirivimab | Casirivimab (REGN10933) is a human monoclonal antibody that targets the SARS-CoV-2 virus, which causes COVID-19. Casirivimab is ineffective against COVID-19 variants. Casirivimab can be used in combination with Imdevimab (HY-P99342), which alters the lung response of K18-hACE2 mice to the SARS-CoV-2 δ variant, effectively reducing viral load and improving symptoms[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: REGN10933. CAS No. 2415933-42-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99341. | |
| Casopitant mesylate | Casopitant mesylate (GW679769B) is a potent, selective, brain permeable and orally active neurokinin 1 (NK1) receptor antagonist. Casopitant mesylate is a second in the class of antiemetics that acts to antagonise the emetogenic effect of Substance P (HY-P0201). Casopitant mesylate is also a substrate and a weak-to-moderate inhibitor of CYP3A4. Casopitant mesylate can be used for chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GW679769B. CAS No. 414910-30-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14405A. | |
| Caspase-3-IN-1 | Caspase-3-IN-1 (compound 11b) is a potent Caspase-3 inhibitor, with an IC50 of 14.5 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 872254-32-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-136975. | |
| Caspase-9 Inhibitor III | Caspase-9 Inhibitor III (Ac-LEHD-cmk) is a caspase-9 inhibitor. Caspase-9 Inhibitor III exhibits protective effects on ischemia-reperfusion-induced myocardial injury[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ac-LEHD-cmk. CAS No. 403848-57-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136744. | |
| Caspofungin | Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-0991; L-743872. CAS No. 162808-62-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17006A. | |
| Caspofungin diacetate | Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-0991 diacetate; L-743872 diacetate. CAS No. 179463-17-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-17006. | |
| Caspofungin diacetate (Standard) | Caspofungin (diacetate) (Standard) is the analytical standard of Caspofungin (diacetate). This product is intended for research and analytical applications. Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-0991 diacetate (Standard); L-743872 diacetate (Standard). CAS No. 179463-17-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17006R. | |
| Castanospermine | Castanospermine is a natural alkaloid that can be extracted from black beans or the Moreton Bay chestnut tree (Castanospermum australae). Castanospermine is an α/ β-glucosidase inhibitor. Castanospermine has anti-inflammatory, antiviral replication and anti-metastatic effects on prostate cancer. Castanospermine can be used as an immunosuppressant to prevent transplant rejection[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 79831-76-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2022. | |
| Casticin | Casticin is a methyoxylated flavonol isolated from Vitex rotundifolia, with antimitotic and anti-inflammatory effect. Casticin inhibits the activation of STAT3. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitexicarpin. CAS No. 479-91-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0516. | |
| Castor oil | Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 8001-79-4. Pack Sizes: 100 mL. Product ID: HY-107799. | |
| Catadegbrutinib | BGB-16673 (BGB-16673) is an orally active, selective BTK PROTAC degrader (IC50=0.69 nM). BGB-16673 ligates BTK to E3 ubiquitin ligase, causing BTK to undergo polyubiquitination, which is then recognized and degraded by the proteasome, thereby exerting efficient BTK degradation activity. BGB-16673 can be used in the research of B-cell malignancies such as chronic lymphocytic leukemia, small lymphocytic lymphoma, and mantle cell lymphoma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BGB-16673; BTK-IN-29. CAS No. 2736508-60-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160141. | |
| Catalase, Aspergillus niger | Catalase, Aspergillus niger is a key enzyme in the metabolism of H2O2 and reactive oxygen species (ROS), and its expression and localization is markedly altered in tumors[1]. Free oxygen radical scavenger. Uses: Scientific research. Category: Signaling pathways. CAS No. 9001-5-2. Pack Sizes: 100 mg; 500 mg. Product ID: HY-135849. | |
| Catalase, Bovine Liver | Catalase, Bovine Liver is an enzyme widely found in various organisms, including animals, plants and microorganisms. Catalase, Bovine Liver mainly exists in the peroxisome of cells and is an important antioxidant enzyme. Catalase, Bovine Liver plays an important role in removing ROS and maintaining the balance of redox state. Catalase, Bovine Liver is closely related to the occurrence and development of tumors. Catalase, Bovine Liver has the potential to be used in tumor prevention research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9001-5-2. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-135849A. | |
| Catalpol | Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Catalpinoside. CAS No. 2415-24-9. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-N0820. | |
| Catechin | Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-Catechin; Cianidanol; Catechuic acid. CAS No. 154-23-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0898. | |
| (-)-Catechin | (-)-Catechin is Catechin's one kind of different structure. Catechin inhibitory enzyme-1 (COX-1), IC50 of 1.4 μM. (-)-Catechin promotes hBM-MSC adipose cell differentiation, increases fat cell differentiation, and PPARγ level[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Cianidanol; (-)-Catechuic acid. CAS No. 18829-70-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0898A. | |
| (±)-Catechin | (±)-Catechin (rel-Cianidanol) is the racemate of the green tea polyphenol Catechin. Catechin has anticancer activity and induces apoptosis. (±)-Catechin has two forms, (+)-Catechin and its enantiomer (-)-Catechin. (+)-Catechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. (-)-Catechin can effectively promote hBM-MSC adipocyte differentiation and increase adiponectin and PPARγ levels. (±)-Catechin has anti-tumor, anti-obesity, anti-diabetic, anti-cardiovascular, anti-infectious, hepatoprotective and neuroprotective effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: rel-Cianidanol; rel-Catechuic acid. CAS No. 7295-85-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-B1890. | |
| (+)-Catechin 3-O-β-D-glucopyranoside | (+)-Catechin 3-O-β-D-glucopyranoside (Compound 13) is an anti-allergic agent found in Edulis Superba. (+)-Catechin 3-O-β-D-glucopyranoside can be used for the research of inflammation and immunology[1]. Uses: Scientific research. Category: Natural products. CAS No. 109280-46-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N16579. | |
| Catechin 7-O-β-D-glucopyranoside | Catechin 7-O-beta-D-glucopyranoside is an orally active natural product found in Ulmus davidiana and Paeonia obovata. Catechin 7-O-β-D-glucopyranoside shows antioxidant and anti-inflammatory activities, and attenuates mitochondrial dysfunction. Catechin 7-O-beta-D-glucopyranoside can be used in intestinal inflammatory disease research[1][2][3]. Uses: Scientific research. Category: Natural products. CAS No. 65597-47-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N10587. | |
| (-)-Catechin gallate | (-)-Catechin gallate is a minor constituent in green tea catechins. (-)-Catechin gallate inhibits the activity of COX-1 and COX-2 enzymes. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Catechin 3-gallate; (-)-Catechin 3-O-gallate. CAS No. 130405-40-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0356. | |
| Catechin (Standard) | Catechin (Standard) is the analytical standard of Catechin. This product is intended for research and analytical applications. Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-Catechin (Standard); Cianidanol (Standard); Catechuic acid (Standard). CAS No. 154-23-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0898R. | |
| Catestatin (human) | Catestatin human, a catecholamine release-inhibitory peptide, is a pleiotropic peptide involved in cardiovascular protection with its antihypertensive and angiogenic effects. Catestatin human can be used in the study of inflammatory diseases [1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Human chromogranin A 352-372. CAS No. 197151-46-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3395. | |
| Catharanthine | Catharanthine ((+)-3,4-Didehydrocoronaridine), a constituent of anticancer vinca alkaloids, inhibits voltage-operated L-type Ca2+ channel (VOCC). Catharanthine has IC50s of 220 μM and 8 μM for VOCC currents in cardiomyocytes and vascular smooth muscle cells (VSMCs), respectively. Catharanthine lowers blood pressure (BP), heart rate (HR). Catharanthine has anti-cancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-3,4-Didehydrocoronaridine. CAS No. 2468-21-5. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0252. | |
| Cathepsin B, Bovine spleen | Cathepsin B, Bovine spleen is a cysteine protease and is involved in multiple kinds of programmed cell death (including apoptosis, pyroptosis, ferroptosis, necroptosis, and autophagic cell death)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9047-22-7. Pack Sizes: 10 U. Product ID: HY-P2780. | |
| Cathepsin C | Cathepsin C is a lysosomal cysteine protease essential for catalytic activation of many serine proteases, including proteinase 3 (PR3), neutrophil elastase (NE), cathepsin G (CTSG), granzyme A/B/C, and mast cell chymase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9032-68-2. Pack Sizes: 10 U. Product ID: HY-P2922. | |
| Cathepsin C-IN-5 | Cathepsin C-IN-5 (compound SF38) is a potent, selective and orally active Cathepsin C inhibitor with IC50s of 59.9 nM, 4.26 μM, >5 μM, >5 μM, >5 μM for Cat C, Cat L, Cat S, Cat B, Cat K, respectively. Cathepsin C-IN-5 inhibits the Cat C activity in bone marrow and blood. Cathepsin C-IN-5 decreases the activation of NSPs (neutrophil serine proteases). Cathepsin C-IN-5 shows anti-inflammatory activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2825567-97-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146584. | |
| Cathepsin G Inhibitor I | Cathepsin G Inhibitor I (Compound 7) is a potent, selective, reversible, competitive, non-peptidic Cathepsin G inhibitor (IC50 = 53 nM; Ki = 63 nM). Cathepsin G Inhibitor I can be used in research related to immune disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 429676-93-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103351. | |
| Cathepsin inhibitor 1 | Cathepsin inhibitor 1 (Compound 25) is a potent and selective inhibitor of Cathepsin, with pIC50s of 7.9, 6.7, 6.0, 5.5 and 5.2 for CatL, CatL2, CatS, CatK, and CatB, respectively. Cathepsin inhibitor 1 is promising for research of osteoarthritis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 225120-65-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100231. | |
| Cathepsin L-IN-2 | Cathepsin L-IN-2 ((Rac)-Z-Phe-Phe-FMK) is an isomer of the Cathepsin L inhibitor Z-Phe-Phe-FMK (HY-141867), with an IC50 of 15 μM for cathepsin L. Z-Phe-Phe-FMK irreversibly blocks the proteolytic function of cathepsins by covalently binding to the cysteine residues in the active center of the enzyme. Cathepsin L-IN-2 and Z-Phe-Phe-FMK can be used to study neurodegenerative diseases (such as GRN-related frontotemporal dementia) and cancer invasion and metastasis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (Rac)-Z-Phe-Phe-FMK. CAS No. 108005-94-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-115733. | |
| Cathepsin X-IN-1 | Cathepsin X-IN-1 (compound 25) is a potent Cathepsin X inhibitor with an IC50 of 7.13 μM. Cathepsin X-IN-1 decreases PC-3 cell migration with low cytotoxic[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2418577-51-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146985. | |
| CATPB | CATPB is a potent, selective free fatty acid receptor 2 (FFA2R/GPR43) antagonist[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1322598-09-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-116263. | |
| Catumaxomab | Catumaxomab, a trifunctional IgG2 antibody, is composed of mouse and rat heavy and light chains and binds to human EpCAM and human CD 3 receptors. The Fc region of Catumaxomab region has binding affinity for FcγR1 (CD 64), FcγRIIA (CD 32a), and FcγRIII (CD 16). Catumaxomab can be used for anti-tumor research, especially epithelial cancers[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 509077-98-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9954. | |
| Caudatin (Standard) | Caudatin (Standard) is the analytical standard of Caudatin (HY-N1983). This product is intended for research and analytical applications. Caudatin is an orally active and brain-penetrant C-21 steroidal found in Cynanchum bungei decne with a variety of biological activities. Caudatin can inhibit cell proliferation, migration, invasion, cause cell phase arrest, induce apoptosis, autophagy, ROS prodution and loss of mitochondrial membrane potential. Caudatin activates PARP, caspase-3, -7, -9, upregulates pro-apoptotic Bad and Bax and downregulates anti-apoptotic Bcl-2 and Bcl-XL. Caudatin suppresses VEGF, FAK phosphorylation, upregulates p21, p27, DR5 protein expression, activates the p38 MAPK, JNK and PPARα/TFEB-mediated autophagy-lysosomal signaling pathways. Caudatin can be used for the research of cancer, inflammation and neurological disease, such as glioma and Alzheimer's disease[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 38395-02-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N1983R. | |
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