MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Bulumtatug | HY-P990977 is an Nectin-4-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MW282 mAb. CAS No. 2862919-81-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990977. |  |
| Bumetanide | Bumetanide (Ro 10-6338; PF 1593), a highly potent loop diuretic, is a Na+-K+-Cl+ cotransporter (NKCC) blocker. Bumetanide is a selective NKCC1 inhibitor, but also inhibits NKCC2, with IC50s of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 10-6338; PF 1593. CAS No. 28395-03-1. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-17468. | |
| Buntanetap | Buntanetap ((+)-Phenserine) is a selective acetylcholinesterase inhibitor. Buntanetap is a multiple neurotoxic protein translation inhibitor with oral activity, including amyloid precursor protein (APP), α-synuclein (αSYN) and huntingtin protein (HTT). Buntanetap reduces the production of β-amyloid precursor protein by blocking its mRNA translation. Buntanetap has anti-inflammatory effects and can be used in the study of Alzheimer's disease and Parkinson's disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-Phenserine; ANVS401. CAS No. 116839-68-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16009. | |
| Buparlisib | Buparlisib (BKM120; NVP-BKM120) is a pan-class I PI3K inhibitor, with blood-brain barrier permeability. Buparlisib has IC50s of 52, 166, 116 and 262 nM for p110α, p110β, p110δ and p110γ, respectively[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BKM120; NVP-BKM120. CAS No. 944396-07-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-70063. | |
| Buparvaquone | Buparvaquone is a hydroxynaphthoquinone antiprotozoal agent related to parvaquone and atovaquone. Uses: Scientific research. Category: Signaling pathways. CAS No. 88426-33-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17581. | |
| Bupivacaine | Bupivacaine is a NMDA receptor inhibitor. Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine can be used for the research of chronic pain[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 38396-39-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B0405. | |
| Bupivacaine hydrochloride | Bupivacaine hydrochloride is a NMDA receptor inhibitor.Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine hydrochloride can be used for the research of chronic pain[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18010-40-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B0405A. | |
| Bupivacaine hydrochloride (Standard) | Bupivacaine (hydrochloride) (Standard) is the analytical standard of Bupivacaine (hydrochloride). This product is intended for research and analytical applications. Bupivacaine hydrochloride is a NMDA receptor inhibitor.Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine hydrochloride can be used for the research of chronic pain[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18010-40-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0405AR. | |
| Buprofezin | Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 69327-76-0. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-B0831. | |
| Bupropion morpholinol | Bupropion morpholinol (Hydroxy Bupropion) is a major metabolite of Bupropion. Bupropion morpholinol inhibits Dopamine, Norepinephrine transporters and the α4β2 nicotinic receptor in vitro. Bupropion morpholinol contributes to antidepressant and smoking cessation activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 357399-43-0. Pack Sizes: 5 mg. Product ID: HY-12766. | |
| Burfiralimab | Burfiralimab (hzVSF-v13) is a monoclonal IgG4 antibody against vimentin expressed on the surface of virus-infected cells, with broad-spectrum antiviral activity and anti-inflammatory effects against virus-induced inflammation. Burfiralimab can be used in severe COVID-19 studies[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: hzVSF-v13. CAS No. 2460809-80-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99490. | |
| Burosumab | Burosumab (KRN23) is a humanized FGF23-neutralizing antibody. By neutralizing FGF23, Burosumab blocks its inhibitory effect on renal phosphate reabsorption, thereby increasing serum phosphate levels and improving abnormal bone mineralization. Burosumab can be used in the research of diseases such as X-linked hypophosphatemia (XLH) and osteomalacia[1][2][3]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: KRN23; N5KG1_C10_LH; UX-023. CAS No. 1610833-03-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9939. | |
| Buspirone | Buspirone is an orally active 5-HT1A receptor agonist, and a dopamine D2 autoreceptorsant antagonist. Buspirone is an anxiolytic agent, and can be used for the generalized anxiety disorder research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 36505-84-7. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1115A. | |
| Buspirone hydrochloride | Buspirone hydrochloride is a 5-HT1A receptor agonist. Buspirone hydrochloride can be used for anxiety and depression research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 33386-08-2. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-B1115. | |
| Buspirone (Standard) | Buspirone (Standard) is the analytical standard of Buspirone. This product is intended for research and analytical applications. Buspirone is an orally active 5-HT1A receptor agonist, and a dopamine D2 autoreceptorsant antagonist. Buspirone is an anxiolytic agent, and can be used for the generalized anxiety disorder research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 36505-84-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1115AR. | |
| Busulfan | Busulfan is a potent alkylating antineoplastic agent. Busulfan causes DNA damage by cross-linking DNAs and DNA and proteins. Busulfan inhibits thioredoxin reductase. Busulfan induces apoptosis. Busulfan is an immunosuppressive and myeloablative chemotherapeutic agent[1][2][3]. Uses: Scientific research. Category: Induced disease models products. CAS No. 55-98-1. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-B0245. | |
| Busulfan-d8 | Busulfan-d8 is a deuterium labeled Busulfan. Busulfan is a potent alkylating antineoplastic agent. Busulfan causes DNA damage by cross-linking DNAs and DNA and proteins. Busulfan inhibits thioredoxin reductase. Busulfan induces apoptosis. Busulfan is an immunosuppressive and myeloablative chemotherapeutic agent[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 116653-28-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0245S. | |
| Butabindide oxalate | Butabindide (UCL-1397) oxalate is a potent, selective tripeptidvl peptidase II (TPP II) inhibitor with Ki values of 7 nM and 10 μM for TPP II and TPP I, respectively. Butabindide oxalate inhibits TPP II to protect CCK-8 against inactivation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: UCL-1397 oxalate. CAS No. 185213-03-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-107759. | |
| Butacaine | Butacaine is a reversible nerve conduction blocker. Butacaine acts on the nervous system and nerve fibers, can cause both sensory and motor paralysis. Butacaine inhibits the NavBh currents. Butacaine can form inclusion complexes with α-cyclodextrin (α-CD) and β-cyclodextrin (β-CD). Butacaine is commonly used as a negative control for other local anesthetics[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 149-16-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-B1007. | |
| Butafenacil | Butafenacil (WC-9717; CGA-276854) is an herbicide that inhibits protoporphyrinogen oxidase[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: WC-9717; CGA-276854. CAS No. 134605-64-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-12464. | |
| Butaprost | Butaprost is a selective prostaglandin E receptor (EP2) agonist with an EC50 of 33 nM and a Ki of 2.4 μM for murine EP2 receptor. Butaprost is less activity against murine EP1, EP3 and EP4 receptors. Butaprost attenuates fibrosis by hampering TGF-β/Smad2 signalling[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 69685-22-9. Pack Sizes: 1 mg (12.24 mM * 200 μL in Methyl acetate); 5 mg (12.24 mM * 1 mL in Methyl acetate). Product ID: HY-100448A. | |
| Butaxamine hydrochloride | Butaxamine (Butoxamin) hydrochloride is a specific β2-adrenergic receptor blocker. Butaxamine hydrochloride inhibits the decreases in urine volume in ethanol-anesthetized, water-diuretic rats[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Butoxamin hydrochloride. CAS No. 5696-15-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-118470. | |
| Butein | Butein is a cAMP-specific PDE inhibitor with an IC50 of 10.4 μM for PDE4[1]. Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 μM for EGFR and p60c-src in HepG2 cells[2]. Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a[3]. Butein is a SIRT1 activator (STAC). Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2,3,4,4-tetrahydroxy Chalcone. CAS No. 487-52-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16558. | |
| (-)-Butin (Standard) | (-)-Butin (Standard) is the analytical standard of (-)-Butin (HY-N6020). This product is intended for research and analytical applications. (-)-Butin is a enantiomer of Butin (HY-N6020B). Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities. Uses: Scientific research. Category: Signaling pathways. CAS No. 492-14-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N6020R. | |
| Butoconazole nitrate | Butoconazole nitrate (RS 35887), an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole nitrate is presumed to function as other imidazole derivatives via inhibition of steroid synthesis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RS 35887. CAS No. 64872-77-1. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg. Product ID: HY-B0293. | |
| Butylated hydroxytoluene | Butylated hydroxytoluene is an antioxidant widely used in foods and in food-related products[1]. Butylated hydroxytoluene is a Ferroptosis inhibitor[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 128-37-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-Y0172. | |
| Butylated hydroxytoluene-d21 | Butylated hydroxytoluene-d21 is the deuterium labeled Butylated hydroxytoluene[1]. Butylated hydroxytoluene is an antioxidant widely used in foods and in food-related products[2]. Butylated hydroxytoluene is a Ferroptosis inhibitor[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 64502-99-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-Y0172S. | |
| Butylated hydroxytoluene-d3 | Butylated hydroxytoluene-d3 is the deuterium labeled Butylated hydroxytoluene[1]. Butylated hydroxytoluene is an antioxidant widely used in foods and in food-related products[2]. Butylated hydroxytoluene is a Ferroptosis inhibitor[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 86819-59-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Y0172S2. | |
| Butylboronic acid | Butylboronic acid is a competitive soybean urease inhibitor with an IC50 of 2.9 mM and a Ki of 1.5 mM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4426-47-5. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g; 50 g; 100 g; 500 g. Product ID: HY-W000932. | |
| Butylhydroxyanisole | Butylhydroxyanisole (Butylated hydroxyanisole) is an antioxidant used as a food additive preservative. Butylhydroxyanisole mediates liver toxicity, retardation in reproductive organ development and learning, and sleep deficit. Butylhydroxyanisole exerts neurotoxic effects and leads to disruption of the brain and nerve development[1][2][3]. Butylhydroxyanisole is a ferroptosis inducer[4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Butylated hydroxyanisole; E320. CAS No. 25013-16-5. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-B1066. | |
| Butyne-DOTA | Butyne-DOTAis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. Butyne-DOTA can be used for conjugation of peptides and radionuclides. Uses: Scientific research. Category: Signaling pathways. CAS No. 2125661-62-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W782078. | |
| Butyric acid-13C4 sodium | Butyric acid-13C4 sodium (Butanoic acid-13C4 sodium) is a stable isotope labeled compound with the activity of promoting cell proliferation and regulating gene expression. Butyric acid-13C4 sodium can be used in metabolic research and compound development to help scientists gain a deeper understanding of the role of short-chain fatty acids in organisms. Butyric acid-13C4 sodium also plays an important role in nutrition and intestinal health research, especially in the regulation of probiotic function and intestinal microbiota. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Butanoic acid-13C4 sodium. CAS No. 286367-75-7. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg. Product ID: HY-W750796. | |
| Butyrolactone 3 | Butyrolactone 3 (MB-3) is a specifical small-molecule inhibitor of the histone acetyltransferase Gcn5 (IC50=100 μM), which has a high affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3. Butyrolactone 3 shows weak inhibitory on CBP (IC50=0.5 mM). Butyrolactone 3 can be used in studies of cancer, metabolic, autoimmune and neurological diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MB-3. CAS No. 778649-18-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129039. | |
| Butyrolactone I | Butyrolactone I is an orally active and ATP-competitive inhibitor of CDK1. Butyrolactone I inhibits NF-κB, cdc2 kinase, Bax, ROS production, modulates the PERK/CHOP. Butyrolactone I mitigates heat-stress-induced Apoptosis. Butyrolactone I shows anti-inflammatory and intestinal protective activity. Butyrolactone I has antitumor effects against non-small cell lung, small cell lung, prostate cancer and leukemia. Butyrolactone I can be used in NASH research[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Olomoucin. CAS No. 87414-49-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-111237. | |
| Butyrospermol | Butyrospermol is a natural product[1]. Uses: Scientific research. Category: Natural products. CAS No. 472-28-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-124045. | |
| Butyrylcarnitine | Butyrylcarnitine is an endogenous metabolite found in plasma. Elevated levels of Butyrylcarnitine are closely associated with abnormalities in lipid and energy metabolism. Butyrylcarnitine can serve as a diagnostic and prognostic indicator for certain diseases, such as heart failure and head and neck cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25576-40-3. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113168. | |
| Butyryl-Coenzyme A sodium | Butyryl-Coenzyme A (Butyryl CoA) sodium is a coenzyme A-containing derivative of Butyric acid. Butyryl-Coenzyme A sodium is responsible for the final step of Butyrate production in bacteria[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Butyryl CoA sodium. CAS No. 125527-24-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-138177. | |
| Butyzamide | Butyzamide is an orally active activator of Mpl, a thrombopoietin (TPO) receptor. Butyzamide increases the phosphorylation level of JAK2, STAT3, STAT5 and MAPK. Butyzamide increases the level of platelets in mouse xenotransplantation assay[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1110767-45-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148748. | |
| BV02 | BV02 is a 14-3-3 inhibitor and an antibacterial agent. BV02 enhances the cleavage of PARP and caspase-3. BV02 induces Apoptosis, Autophagy, and enhances Akt activation. BV02 has anti-B. melitensis infection and epilepsy-promoting effects. BV02 can also be used in colitis research. Uses: Scientific research. Category: Signaling pathways. CAS No. 292870-53-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101985. | |
| BV6 | BV6 is an antagonist of cIAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family. BV6 shows an IC50 of 7.2 μM in MTS assays in HCC193 cells. BV6 can be used in the research of endometrial cancer and endometriosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1001600-56-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16701. | |
| BVT.13 | BVT.13 is an orally active and selective PPARγ agonist with a maximal efficacy similar to that of Rosiglitazone (HY-17386). In addition, BVT.13 exhibits antidiabetic activity in ob/ob mice[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 756813-87-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114853. | |
| BVT-14225 | BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 52 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 376638-65-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18055. | |
| BVT173187 | BVT173187 is a selective inhibitor of the neutrophil formyl peptide receptor FPR1, with activity that inhibits FPR1 activation. BVT173187 inhibits FPR1 agonist-induced activation in neutrophils, reduces adhesion molecule mobilization and superoxide anion production, and has inhibitory activity on FPR1 similar to that of earlier described peptide antagonists, but also has effects on C5aR and CXCR signaling. Uses: Scientific research. Category: Signaling pathways. CAS No. 1374984-75-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117971. | |
| BW-180C | BW-180C ([D-Ala2, D-Leu5]-Enkephalin; DADLE) is an δ opioid receptor (DOR) agonist, which belongs to the enkephalin family. Neuroprotective agent. BW-180C reversibly inhibits cellular transcription in neurons without causing cell injury[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: [D-Ala2, D-Leu5]-Enkephalin; DADLE. CAS No. 63631-40-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105343. | |
| BW 245C | BW 245C is a prostanoid DP-receptor (DP1) agonist, used to study stroke. Uses: Scientific research. Category: Signaling pathways. CAS No. 72814-32-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101987. | |
| BW-723C86 | BW-723C86 is an orally active and a selective 5-HT2B receptor agonist. BW-723C86 exhibits anxiolytic-like actions. BW-723C86 also causes hyperphagia and reduced grooming in rats. BW-723C86 dilates pulmonary arteries and inhibits liquid meal-induced gastric accommodation[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 160521-72-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101369. | |
| BWA-522 | BWA-522 is an orally active PROTAC degrader targeting full-length androgen receptor (AR-FL) and androgen receptor splice variant 7 (AR-V7). BWA-522 antagonizes the N-terminal domain (AR-NTD) of the androgen receptor, suppresses AR downstream signaling proteins and induces cancer cells apoptosis. BWA-522 inhibits tumor growth in LNCaP xenograft mouse model. BWA-522 can be used for the research of prostate cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3042820-12-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149433. | |
| BW A868C | BW A868C, a hydantoin compound, is a BW245C structural analogue. BW A868C is a selective and potent competitive prostaglandin D2 (PGD2) antagonist. BW A868C has no effect on other prostaglandin receptors (IP, EP1, EP2, TP and FP)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 118675-50-6. Pack Sizes: 1 mg (21.76 mM * 100 μL in Ethanol). Product ID: HY-50848. | |
| BWC0977 formic | BWC0977 formic is an antibacterial agent that inhibits bacterial DNA replication via inhibition of DNA gyrase and topoisomerase IV. BWC0977 formic exhibits a minimum inhibitory concentration (MIC90) of 0.03-2?μg/mL against MDR (Multi-Drug Resistant) Gram-negative bacteria[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3027162-72-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-162959A. | |
| BX430 | BX430 is a potent and selective noncompetitive allosteric human P2X4 receptor channels antagonist with an IC50 of 0.54 μM. BX430 has species specificity. BX430 is used for chronic pain and cardiovascular disease. Uses: Scientific research. Category: Signaling pathways. CAS No. 688309-70-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110237. | |
| BX471 | BX471 (ZK-811752) is an orally active, potent and selective non-peptide CCR1 antagonist with a Ki of 1 nM, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZK-811752. CAS No. 217645-70-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12080. | |
| BX471 hydrochloride | BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZK-811752 hydrochloride. CAS No. 288262-96-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12080A. | |
| BX795 | BX795 is a potent and selective inhibitor of PDK1, with an IC50 of 6 nM. BX795 is also a potent and relatively specific inhibitor of TBK1 and IKKε, with an IC50 of 6 and 41 nM, respectively. BX795 blocks phosphorylation of S6K1, Akt, PKCδ, and GSK3β, and has lower selectivity over PKA, PKC, c-Kit, GSK3β etc. BX795 modulates autophagy[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 702675-74-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10514. | |
| BX-912 | BX-912 is a direct, selective, and ATP-competitive PDK1 inhibitor (IC50=26 nM). BX-912 blocks PDK1/Akt signaling in tumor cells and inhibits the anchorage-dependent growth of a variety of tumor cell lines in culture or induces apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 702674-56-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11005. | |
| BYK204165 | BYK204165 is a potent and selective PARP1 inhibitor. BYK204165 inhibits cell-free recombinant human PARP-1 (hPARP-1) with a pIC50 of 7.35 (pKi=7.05), and murine PARP-2 (mPARP-2) with a pIC50 of 5.38, respectively. BYK204165 displays 100-fold selectivity for PARP-1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1104546-89-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108632. | |
| Bz-dA | Bz-dA (N6-Benzoyl-2'-deoxyadenosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N6-Benzoyl-2'-deoxyadenosine. CAS No. 4546-72-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W011125. | |
| Bz-Nle-Lys-Arg-Arg-AMC | Bz-Nle-Lys-Arg-Arg-AMC can be used for protease activity assay. In 0.1mL Tris-HCl buffer (50 mM, pH 7.8), Bz-Nle-Lys-Arg-Arg-AMC was hydrolyzed, and the release rate of AMC was observed[1]. Uses: Scientific research. Category: Peptides. CAS No. 863975-32-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P2435. | |
| Bz-OMe-rA | Bz-OMe-rA is a nucleoside analog[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Benzoyl-2-O-methyladenosine. CAS No. 85079-00-1. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W141394. | |
| Bz-RS-iSer(3-Ph)-OMe | Bz-RS-iSer(3-Ph)-OMe (compound 2), a Taxol derivative, inhibits HSV replication cycle at low cytotoxicity, blocks mitotic divisions of Vero cells, influences M-MSV induced tumor size and affects immune response by inhibiting PHA-induced T lymphocyte proliferation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 32981-85-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-W009245. | |
| C004019 | C004019 is a BBB-penetrable and small-molecule PROTAC that targets tau. C004019 can simultaneously recruit tau and E3 ligase, and effectively clear tau proteins by promoting the ubiquitination and proteasome-dependent degradation of tau, thereby improving synaptic and cognitive functions in Alzheimer's disease (AD) mice. C004019 can be used in the research of AD and tau protein-related diseases. (Pink: Ligand for target protein (HY-138679); Black: linker (HY-140189); Blue: E3 Ligase Ligand (HY-138678))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2417159-57-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138669. | |
| C-021 | C-021 is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor with an IC50 of 18 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 864289-85-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103364. | |
| C-021 dihydrochloride | C-021 dihydrochloride is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 dihydrochloride effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor with an IC50 of 18 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1784252-84-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-103364A. | |
| C12-200 | C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1220890-25-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145405. | |
| C12FDG | C12FDG (5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside) is a lipophilic green fluorescent substrate for β-galactosidase detection. C12-FDG is more sensitive than Fluorescein di(β-D-galactopyranoside) (HY-101895) for beta-galactosidase activity determinations in animal cells (Ex/Em = 488/523 nm)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside. CAS No. 138777-25-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126839. | |
| C12 NBD Sphingomyelin | C12 NBD sphingomyelin is an active derivative of Sphingomyelin (HY-113498) that is tagged with fluorescent C12 nitrobenzoxadiazole (C12 NBD). C12 NBD sphingomyelin can be used as a sphingomyelinase substrate for studying the metabolism and transport of sphingomyelins (Ex=470 nm, Em=525 nm)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 254117-01-6. Pack Sizes: 100 μg. Product ID: HY-D1584. | |
| C14-4 | C14-4 is an ionizable lipid utilized for the synthesis of lipid nanoparticles (LNPs). C14-4 enhances mRNA delivery, enabling the effective transport of mRNA to primary human T cells, which in turn induces functional protein expression. C14-4 demonstrates high transfection efficiency while maintaining low cytotoxicity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2639634-80-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-148842. | |
| C14 Ceramide (d18:1/14:0) | C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's and diabetes research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 123408-74-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-124177A. | |
| C16-Ceramide (d18:1/16:0) | C16-Ceramide (d18:1/16:0) is a natural small molecule activating p53 through the direct and selective binding[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: C16-Ceramide. CAS No. 24696-26-2. Pack Sizes: 10 mM * 1 mL in Ethanol; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100354. | |
| C16-Ceramide-d31 | C16-Ceramide-d31 is deuterium labeled C16-Ceramide. Uses: Scientific research. Category: Signaling pathways. CAS No. 852043-41-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-100354S4. | |
| C16-Dihydroceramide | C16-Dihydroceramide (N-Palmitoyl sphinganine) is an ester product. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Palmitoyl sphinganine; (2S,3R)-2-N-Palmitoyloctadecasphinganine. CAS No. 5966-29-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W590669. | |
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