Selleck Chemicals - Products
United States; Europe
Selleck Chemicals supplies bioactive small molecules, inhibitors, compound libraries, antibodies, natural products and related research reagents for life science research.
| Product | Description | |
|---|---|---|
| Anti-Flag Affinity Gel | Anti-Flag Affinity Gel is a Protein A purIFied murine IgG2b Monoclonal antibody covalently attached to sepharose 4B wHICh could used on Flag fusion protein purIFication, IP and CO-IP. Group: Kits. Pack Sizes: 1 ml Kit. Product ID: B23101. Storage Conditions: 3 years-20°C powder 2 years-80°C in solvent. |  United States; Europe |
| Anti-Flag Affinity Gel | Anti-Flag Affinity Gel is a Protein A purIFied murine IgG2b Monoclonal antibody covalently attached to sepharose 4B wHICh could used on Flag fusion protein purIFication, IP and CO-IP. Group: Kits. Pack Sizes: 5 ml Kit. Product ID: B23102. Storage Conditions: 3 years-20°C powder 2 years-80°C in solvent. | United States; Europe |
| Anti-Flag magnetic beads | Anti-Flag magnetic beads is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody. It is recommended to use for co-immunoprecipitation and protein purification. Group: Kits. Pack Sizes: 5 mL. Product ID: B26102. Storage Conditions: 3 years-20°C powder 2 years-80°C in solvent. | United States; Europe |
| Anti-Flag magnetic beads | Anti-Flag magnetic beads is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody. It is recommended to use for co-immunoprecipitation and protein purification. Group: Kits. Pack Sizes: 1 mL. Product ID: B26101. Storage Conditions: 3 years-20°C powder 2 years-80°C in solvent. | United States; Europe |
| Anti-HA magnetic beads | Anti-HA magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with high quality mouse IgG2b monoclonal antibody, used for co-immunoprecipitation and protein purification. Group: Kits. Pack Sizes: 5 mL. Product ID: B26202. Storage Conditions: 3 years-20°C powder 2 years-80°C in solvent. | United States; Europe |
| Anti-HA magnetic beads | Anti-HA magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with high quality mouse IgG2b monoclonal antibody, used for co-immunoprecipitation and protein purification. Group: Kits. Pack Sizes: 1 mL. Product ID: B26201. Storage Conditions: 3 years-20°C powder 2 years-80°C in solvent. | United States; Europe |
| Anti-human CD28-InVivo | Anti-human CD28-InVivo (Clone: 9.3) monoclonal antibody reacts with human CD28, a 45 kDa costimulatory receptor and a member of the Ig superfamily. It stimulate the proliferation of human T cells in vitro. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2127. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-human CD3-InVivo | The OKT-3 monoclonal antibody reacts with human CD3ε which is a 20 kDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily.The OKT-3 antibody has immunosuppressive properties in vivo and has been shown to effectively treat renal, heart and liver allograft rejection. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2111. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-human / mouse TGF-β-InVivo | The 1D11.16.8 monoclonal antibody reacts with mouse, human, rat, monkey, hamster, canine and bovine TGF-β (transforming growth factor beta) isoforms 1, 2 and 3.The 1D11.16.8 monoclonal antibody is a neutralizing antibody. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2113. Formula: Bovine TGFβ isoform 2. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse CD16/CD32-InVivo | The 2.4G2 monoclonal antibody (Clone: 2.4G2)reacts specifically with mouse CD16 (FcγRIII) and CD32 (FcγRII). It has also been reported to react non-specifically via its Fc domain to FcγRI. The 2.4G2 antibody is commonly used in flow cytometry staining experiments to prevent non-specific binding of IgG to the FcγIII and FcγII, and possibly FcγI, receptors prior to staining with antigen specific primary antibodies. For Fc receptor blocking of mouse samples in flow cytometry experiments, add 0.25 μg of anti-mouse CD16/32 antibody per 10? cells in a total reaction volume of 100 μL. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2110. Formula: BALB/c mouse macrophage cell line J774. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse CD19-InVivo | Anti-mouse CD19-InVivo reacts with mouse CD19, a B cell-specific 95 kDa transmembrane glycoprotein of the immunoglobulin superfamily. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2149. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse CD25 (IL-2Rα)-InVivo | The PC-61.5.3 monoclonal antibody reacts with mouse IL-2Rα also known as CD25, Ly-43, p55, or Tac.The PC-61.5.3 antibody has been shown to inhibit the binding of IL-2 to both the low and high affinity IL-2 receptor forms. Additionally, the PC-61.5.3 antibody is commonly used to deplete CD4+FoxP3+ T regulatory cells in vivo. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2107. Formula: IL-2-dependent cytolytic mouse T cell clone B6.1. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse CD28(37.51)-InVivo | Anti-mouse CD28(37.51)-InVivo reacts with mouse CD28, a 45 kDa costimulatory receptor and a member of the Ig superfamily. CD28 is expressed by thymocytes, most peripheral T cells, and NK cells. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2166. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse CD28-InVivo | The PV-1 monoclonal antibody(Clone: PV-1) reacts with mouse CD28.The PV-1 antibody has been shown to stimulate the proliferation and cytokine production by activated T and NK cells. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2108. Formula: C57BL/6 mouse T cell lymphoma EL-4 cells. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse CD3ε-InVivo | The 145-2C11 monoclonal antibody reacts with mouse CD3ε which is a 20 kDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The 145-2C11 antibody has been shown to induce T lymphocyte activation, proliferation, and apoptosis in vitro via binding and stimulating the TCR. When used in vivo the antibody is reported to produce T cell activation, anergy, or death. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2104. Formula: Mouse BM10-37 cytotoxic T cells. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse CD3-InVivo | Anti-mouse CD3-InVivo reacts with mouse CD3, a transmembrane cell-surface protein that belongs to the immunoglobulin superfamily.CD3 is expressed on T lymphocytes, NK-T cells, and to varying degrees on developing thymocytes. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2167. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse CD40-InVivo | Anti-mouse CD40-InVivo reacts with mouse CD40 also known as Bp50. CD40 is a type I transmembrane glycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2136. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse CD4-InVivo | Anti-mouse CD4 antibody(Clone: GK1.5) reacts with mouse CD4, which is a 55 kDa cell surface type I membrane glycoprotein. CD4 is a co-receptor of the T cell receptor (TCR) and assists the latter in communicating with antigen-presenting cells. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2101. Formula: Mouse CTL clone V4. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse CD8α-InVivo | Anti-mouse CD8α (Clone:2.43)reacts with mouse CD8α. CD8 is a transmembrane glycoprotein that acts as a co-receptor for the T cell receptor (TCR). It binds to class I MHC molecules displayed by antigen presenting cells (APC). Group: Antibodies. Pack Sizes: 1mg. Product ID: A2102. Formula: Mouse CTL clone L3. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse CSF1R (CD115)-InVivo | Anti-mouse CSF1R (CD115)-InVivo reacts with mouse colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115. CSF1R is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2159. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse CTLA-4 (CD152)-InVivo | Anti-mouse CTLA-4 (CD152) antibody (Clone:9H10) reacts with mouse CTLA-4 (cytotoxic T lymphocyte antigen-4) also known as CD152. Anti-mouse CTLA-4 (CD152) antibody has been shown to promote T cell co-stimulation by blocking CTLA-4 binding to the B7 co-receptors, allowing for CD28 binding. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2103. Formula: Mouse CTLA-4-human IgG1 fusion protein. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse CXCR3 (CD183)-InVivo | Anti-mouse CXCR3 (CD183)-InVivo reacts with mouse CXCR3 also known as CD183, a 38 kDa chemokine receptor for CXCL9 (MIG), CXCL10 (IP-10), and CXCL11 (ITAC). Group: Antibodies. Pack Sizes: 1mg. Product ID: A2147. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse / human/rat CCL2 (MCP-1)-InVivo | Anti-mouse / human/rat CCL2 (MCP-1)-InVivo (Clone: 2H5) antibody reacts with mouse, human, and rat CCL2, also known as monocyte chemoattractant protein 1 (MCP-1). MCP-1 is a 13 kDa chemokine produced mainly by monocytes / macrophages and is a potent monocyte-attracting chemokine. The 2H5 antibody has been shown to neutralize the biological effects of CCL2 in vivo. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2132. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse / human/rat CD47 (IAP)-InVivo | Anti-mouse / human/rat CD47 (IAP)-InVivo reacts with mouse CD47 otherwise known as integrin-associated protein (IAP). CD47 is an approximately 50 kDa glycosylated five transmembrane protein that is ubiquitously expressed by both hematopoietic cells such as T and B lymphocytes, monocytes, platelets and erythrocytes and non-hematopoietic cells. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2140. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse IFNAR-1-InVivo | Anti-mouse IFNAR-1-InVivo monoclonal antibody (Clone: MAR1-5A3) reacts with mouse IFNAR-1 (IFN alpha / beta receptor subunit 1). Anti-mouse IFNAR-1-InVivo has been shown to inhibit Type I IFN receptor signaling in vitro and in vivo. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2121. Formula: Extracellular domain of mouse IFNAR-1. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse IFNγ-InVivo | The R4-6A2 monoclonal antibody reacts with mouse IFNγ (interferon gamma) which is a 20 kDa soluble pleiotropic cytokine and the sole member of the type II class of interferons. The R4-6A2 antibody has been shown to neutralize both natural and recombinant IFNγ. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2105. Formula: Partially-purified native mouse IFNγ. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse IFNγ (XMG1.2)-InVivo | Anti-mouse IFNγ (XMG1.2)-InVivo reacts with mouse IFNγ (interferon gamma) a 20 kDa soluble pleiotropic cytokine and the sole member of the type II class of interferons. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2152. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse IL-17A-InVivo | Anti-mouse IL-17A-InVivo monoclonal antibody (Clone:17F3) reacts with mouse IL-17A which is a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. Anti-mouse IL-17A-InVivo has been shown to neutralize IL-17A in vivo. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2120. Formula: Mouse IL-17A cross-linked to OVA. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse IL-4-InVivo | The 11B11 monoclonal antibody reacts with mouse IL-4 (interleukin-4) which is a multifunctional 14 kDa cytokine.The 11B11 monoclonal antibody has been shown to neutralize the bioactivity of natural or recombinant IL-4. Group: Antibodies. Pack Sizes: 5mg. Product ID: A2109. Formula: Partially purified native mouse IL-4. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse IL-6-InVivo | Anti-mouse IL-6-InVivo monoclonal antibody (Clone:MP5-20F3) can reacts with mouse IL-6 (interleukin-6) which is a 21-28 kDa cytokine that is expressed by many cell types, including T lymphocytes, B lymphocytes, monocytes, fibroblasts, and endothelial cells. Anti-mouse IL-6-InVivo has been shown to neutralize the bioactivity of natural or recombinant IL-6. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2118. Formula: Recombinant mouse IL-6. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse Ly6G-InVivo | Anti-mouse Ly6G-InVivo reacts with mouse Ly6G. Ly6G is a 21-25 kDa member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2158. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse Ly6G/Ly6C (Gr-1)-InVivo | Anti-mouse Ly6G/Ly6C (Gr-1)-InVivo reacts strongly with mouse Ly6G and weakly with mouse Ly6C previously referred to as GR-1. Ly6G is a 21-25 kDa member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2135. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse NK1.1-InVivo | The PK136 monoclonal antibody(Clone: PK136) reacts with mouse NK1.1 also known as CD161b/CD161c, KLRB1, NKR-P1A and Ly-55. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2114. Formula: Mouse spleen and bone marrow cells enriched for NK1+ cells. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse PD-1 (CD279)(29F.1A12)-InVivo | Anti-mouse PD-1 (CD279)(29F.1A12)-InVivo reacts with mouse PD-1 (programmed death-1) also known as CD279. PD-1 is a 50-55 kDa cell surface receptor encoded by the Pdcd1 gene that belongs to the CD28 family of the Ig superfamily. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2165. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse PD-1 (CD279)-InVivo | Anti-mouse PD-1 (CD279)-InVivo(Clone:RMP1-14) reacts with mouse PD-1 (programmed death-1) also known as CD279. PD-1 is a 50-55 kDa cell surface receptor encoded by the Pdcd1 gene that belongs to the CD28 family of the Ig superfamily. Group: Antibodies. Pack Sizes: 5mg. Product ID: A2122. Storage Conditions: Store the undiluted solution at 4°C and avoid freeze-thaw cycle. | United States; Europe |
| Anti-mouse PD-L1 (B7-H1)-InVivo | Anti-mouse PD-L1 (B7-H1)-InVivo (Clone:10F.9G2) monoclonal antibody reacts with mouse PD-L1 (also known as B7-H1, CD274). The 10F.9G2 antibody has been shown to block the interaction between PD-L1 and PD-1 and between PD-L1 and B7-1 (CD80). Group: Antibodies. Pack Sizes: 1mg. Product ID: A2115. Formula: Mouse CD274. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse/rat IL-1β-InVivo | Anti-mouse/rat IL-1β-InVivo reacts with precursor and mature secreted forms of mouse and rat IL-1β a 17 kDa pro-inflammatory cytokine produced primarily by monocytes. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2142. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-mouse TNFα-InVivo | Anti-mouse TNFα-InVivo reacts with mouse TNFα (tumor necrosis factor-alpha), a multifunctional proinflammatory cytokine. TNFα dysregulation is been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. TNFα knockout animals display defects in response to bacterial infection, characterized by defects in forming organized follicular dendritic cell networks and germinal centers with a lack of primary B cell follicles. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2124. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Anti-Myc magnetic beads | Anti-Myc magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody.it is recommended to use for co-immunoprecipitation and protein purification. Group: Kits. Pack Sizes: 1 mL. Product ID: B26301. Storage Conditions: 3 years-20°C powder 2 years-80°C in solvent. | United States; Europe |
| Anti-Myc magnetic beads | Anti-Myc magnetic beads kit is based on hydroxyl magnetic beads covalently coupling with mouse IgG1 monoclonal antibody.it is recommended to use for co-immunoprecipitation and protein purification. Group: Kits. Pack Sizes: 5 mL. Product ID: B26302. Storage Conditions: 3 years-20°C powder 2 years-80°C in solvent. | United States; Europe |
| AOA (Aminooxyacetic acid) hemihydrochloride | AOA (Aminooxyacetic acid) hemihydrochloride is an inhibitor of aminobutyrate aminotransferase involved in amino acid and polyamine metabolism. AOA hemihydrochloride is also a CBS (cystathionine β-synthase) inhibitor. AOA hemihydrochloride inhibits the malate-aspartate shuttle (MAS). Group: Inhibitors. Alternative Names: Carboxymethoxylamine hemihydrochloride, AOAA hemihydrochloride, Aminooxyacetate hemihydrochloride. CAS No. 2921-14-4. Pack Sizes: 25mg. Product ID: S4989. Formula: C2H5NO3.1/2HCl. Smiles: C(C(=O)O)ON.C(C(=O)O)ON.Cl. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Apatinib (YN968D1) | Apatinib (Rivoceranib, YN968D1) is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret (c-Ret), c-Kit and c-Src, respectively. Apatinib induces both autophagy and apoptosis. Group: Inhibitors. Alternative Names: Rivoceranib, YN968D1. CAS No. 811803-05-1. Pack Sizes: 5mg. Product ID: S5248. Formula: C24H23N5O. Smiles: O=C(NC1=CC=C(C=C1)C2(CCCC2)C#N)C3=C(NCC4=CC=NC=C4)N=CC=C3. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| Apilimod (STA-5326) | Apilimod is a potent and orally-available inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases. Apilimod (STA-5326) inhibits IL-12 with IC50 of 1 nM, 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs, human monocytes and mouse PBMCs, respectively. Apilimod (STA-5326) is also a cell permeable small molecule that specifically inhibits PIKfyve with IC50 of 14 nM. Group: Inhibitors. Alternative Names: STA-5326. CAS No. 541550-19-0. Pack Sizes: 5mg. Product ID: S6414. Formula: C23H26N6O2. Smiles: CC1=CC(=CC=C1)C=NNC2=CC(=NC(=N2)OCCC3=CC=CC=N3)N4CCOCC4. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| Aprotinin | Aprotinin is a small protein serine protease inhibitor (Kd=0.06 pM for bovine β-trypsin), used to reduce perioperative blood loss and transfusion. Group: Inhibitors. CAS No. 9087-70-1. Pack Sizes: 10mg. Product ID: S7377. Formula: C284H432N84O79S7. Smiles: CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC2CSSCC3C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)N4CCCC4C(=O)N5CCCC5C(=O)NC(C(=O)NC(C(=O)NCC(=O)N6CCCC6C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N3)CC(=O)O)CCC(=O)O)C)CO)CCCCN)CC7=CC=CC=C7)CC(=O)N)CC(=O)N)CCCNC(=N)N)CCCCN)C)CCCNC(=N)N)NC(=O)CNC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)CCC(=O)N)C(C)O)CC8=CC=CC=C8)C(C)C)CC9=CC=C(C=C9)O)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)C)CCCCN)C(C)O)CC1=CC=C(C=C1)O)CCC(=O)O)CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC(=O)O)NC(=O)C1CCCN1C(=O)C(CCCNC(=N)N)N)C(=O)NCC(=O)NCC(=O)NC(C)C(=O)O)C(C)O)CCCNC(=N)N)CCSC)CC(C)C)C)CCCCN)C)CC(=O)N)CC1=CC=C(C=C1)O)CC1=CC=CC=C1)CC1=CC=C(C=C1)O)CCCNC(=N)N)C(C)CC. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Arginase 1 Antibody [B11F1] | ARG1 / Arignase 1,Arginase 1,Arginase 1/ARG1 / liver Arginase,Arginase I,Arginase-1,Liver Arginase. Group: Antibodies. Alternative Names: ARG1, Arginase 1, liver Arginase, arginase, liver, Arg-1. Pack Sizes: 20uL. Product ID: F3269. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Arginase-1 Antibody [N1K20] | ARG1 / Arignase 1,Arginase 1,Arginase 1/ARG1 / liver Arginase,Arginase I,Arginase-1,Liver Arginase. Group: Antibodies. Alternative Names: ARG1 / Arignase 1,Arginase 1,Arginase-1,Liver Arginase. Pack Sizes: 20ul. Product ID: F0421. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Armenian hamster IgG isotype control-InVivo | Armenian hamster IgG isotype control-InVivo is ideal for use as an isotype control for Armenian hamster IgG antibodies in most in vivo and in vitro applications. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2150. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| ART26.12 | ART26.12 is an inhibitor of fatty acid-binding protein 5 (FABP5) that selectively binds to FABP5 over FABP3, FABP4, and FABP7, exhibiting antinociceptive properties. It alleviates oxaliplatin-induced pain through lipid modulation and cannabinoid receptor activation, with potential for preventing and treating oxaliplatin-induced peripheral neuropathy (OIPN). Group: Inhibitors. CAS No. 2766800-24-0. Pack Sizes: 5mg. Product ID: E4780. Formula: C29H28O6. | United States; Europe |
| ART558 | ART558 is a potent, selective, low molecular weight, allosteric inhibitor of DNA Polθ with an IC50 of 7.9 nM. Group: Inhibitors. CAS No. 2603528-97-6. Pack Sizes: 5mg. Product ID: S9936. Formula: C21H21F3N4O2. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| ARV-825 | ARV-825 is a BRD4 Inhibitor that recruits BRD4 to the E3 ubiquitin ligase cereblon, leading to fast, efficient, and prolonged degradation of BRD4 and sustained down-regulation of MYC. Group: Inhibitors. CAS No. 1818885-28-7. Pack Sizes: 2mg. Product ID: S8297. Formula: C46H47ClN8O9S. Smiles: CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NC4=CC=C(C=C4)OCCOCCOCCOCCNC5=CC=CC6=C5C(=O)N(C6=O)C7CCC(=O)NC7=O)C8=CC=C(C=C8)Cl)C. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| AS1517499 | AS1517499 is a novel and potent STAT6 inhibitor with an IC50 value of 21 nM. Group: Inhibitors. CAS No. 919486-40-1. Pack Sizes: 5mg. Product ID: S8685. Formula: C20H20ClN5O2. Smiles: C1=CC=C(C=C1)CNC2=NC(=NC=C2C(=O)N)NCCC3=CC(=C(C=C3)O)Cl. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| AS1842856 | AS1842856 is a cell-permeable inhibitor that blocks the transcription activity of Foxo1 with IC50 of 33 nM. It could directly bind to the active Foxo1, but not the Ser256-phosphorylated form. AS1842856 suppresses autophagy. Group: Inhibitors. CAS No. 836620-48-5. Pack Sizes: 10mg. Product ID: S8222. Formula: C18H22FN3O3. Smiles: CCN1C=C(C(=O)C2=C1C=C(C(=C2N)F)NC3CCCCC3)C(=O)O. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| AS2863619 | AS2863619 is a small-molecule cyclin-dependent kinase CDK8/19 inhibitor with IC50 of 0.6099 nM and 4.277 nM, respectively. AS2863619 is a potent Foxp3 inducer in Tconv cells. Group: Inhibitors. CAS No. 2241300-51-4. Pack Sizes: 2mg. Product ID: S8903. Formula: C16H14Cl2N8O. Smiles: CC1=NC2=C(N1)C=C(C=C2)N3C4=C(C=NC=C4)N=C3C5=NON=C5N.Cl.Cl. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| ASC/TMS1 Antibody [C20P14] | ASC,ASC/TMS1,ASC/TMS1 / PYCARD,TMS1/ASC. Group: Antibodies. Alternative Names: ASC,ASC/TMS1,ASC/TMS1 / PYCARD. Pack Sizes: 20ul. Product ID: F0468. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| ASP2215 (Gilteritinib) | Gilteritinib (ASP2215) is a small-molecule FLT3/AXL inhibitor with IC50 values of 0.29 nM and 0.73 nM for FLT3 and AXL, respectively. It inhibits FLT3 at an IC50 value that was approximately 800-fold more potent than the concentration required to inhibit c-KIT (230 nM). Group: Inhibitors. CAS No. 1254053-43-4. Pack Sizes: 5mg. Product ID: S7754. Formula: C29H44N8O3. Smiles: CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC(=C(C=C2)N3CCC(CC3)N4CCN(CC4)C)OC)NC5CCOCC5. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Atezolizumab (anti-PD-L1) | Atezolizumab (anti-PD-L1) is a fully humanized, IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD-1 and B7.1, but not the interaction of PD-L2 with PD-1. MW : 145 KD. Group: Antibodies. Alternative Names: MPDL3280A. CAS No. 1380723-44-3. Pack Sizes: 5mg. Product ID: A2004. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| ATF3 Antibody [B23E24] | ATF3,ATF-3. Group: Antibodies. Alternative Names: ATF3. CAS No. Pack Sizes: 20uL. Product ID: F1121. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| ATF-4 Antibody [L3P6] | ATF4,ATF-4,CREB-2/ATF-4. Group: Antibodies. Alternative Names: ATF4,CREB-2/ATF-4. Pack Sizes: 20uL. Product ID: F0318. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| ATF6 Antibody [M6P20] | ATF6,ATF-6,ATF-6α. Group: Antibodies. Alternative Names: ATF6,ATF-6α. Pack Sizes: 20uL. Product ID: F0822. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Atglistatin | Atglistatin is a highly potent, and selective inhibitor of adipose triglyceride lipase (ATGL) with IC50 of 0.7 μM, high selectivity over other key metabolic lipases. Group: Inhibitors. CAS No. 1469924-27-3. Pack Sizes: 10mg. Product ID: S7364. Formula: C17H21N3O. Smiles: CN(C)C1=CC=C(C=C1)C2=CC(=CC=C2)NC(=O)N(C)C. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| ATN-161 | ATN-161 is a novel small peptide antagonist of integrin α5β1. It binds to several integrins, including α5β1 and αvβ3, that play a role in angiogenesis and tumor progression. Group: Inhibitors. Alternative Names: Ac-PHSCN-NH2. CAS No. 262438-43-7. Pack Sizes: 5mg. Product ID: S8454. Formula: C23H35N9O8S. Smiles: CC(=O)N1CCCC1C(=O)NC(CC2=CN=CN2)C(=O)NC(CO)C(=O)NC(CS)C(=O)NC(CC(=O)N)C(=O)N. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Atorvastatin | Atorvastatin is a lipid lowering agent. It is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the rate-determining enzyme in cholesterol biosynthesis via the mevalonate pathway. Atorvastatin activates autophagy. Group: Inhibitors. CAS No. 134523-00-5. Pack Sizes: 25mg. Product ID: S5715. Formula: C33H35FN2O5. Smiles: CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)O)O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| ATP (Adenosine 5'-triphosphate) | ATP (Adenosine-Triphosphate, Adenosine 5'-triphosphate) is a multifunctional nucleoside triphosphate and an important endogenous signaling molecule in immunity and inflammation. Group: Inhibitors. Alternative Names: Adenosine-Triphosphate, Adenosine 5'-triphosphate. CAS No. 56-65-5. Pack Sizes: 25mg. Product ID: S5260. Formula: C10H16N5O13P3. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| Axitinib (AG-013736) | Axitinib is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM in Porcine aorta endothelial cells, respectively. Group: Inhibitors. Alternative Names: AG 013736. CAS No. 319460-85-0. Pack Sizes: 50mg. Product ID: S1005. Formula: C22H18N4OS. Smiles: CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| AZD1390 | AZD1390 is a first-in-class orally available and CNS penetrant ATM inhibitor with an IC50 of 0.78 nM in cells and >10,000-fold selectivity over closely related members of the PIKK family of enzymes and excellent selectivity across a broad panel of kinases. Group: Inhibitors. CAS No. 2089288-03-7. Pack Sizes: 2mg. Product ID: S8680. Formula: C27H32FN5O2. Smiles: CC(C)N1C2=C(C=NC3=CC(=C(C=C32)C4=CN=C(C=C4)OCCCN5CCCCC5)F)N(C1=O)C. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| AZD2281 (Olaparib) | Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in cell-free assays, 300-times less effective against tankyrase-1. Olaparib induces significant autophagy that is associated with mitophagy in cells with BRCA mutations. Group: Inhibitors. Alternative Names: Ku-0059436. CAS No. 763113-22-0. Pack Sizes: 10mg. Product ID: S1060. Formula: C24H23FN4O3. Smiles: C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| AZD3965 | AZD3965 is a potent, selective and orally available monocarboxylate transporter 1 (MCT1) inhibitor with a binding affinity of 1.6 nM, 6-fold selective over MCT2. Phase 1. Group: Inhibitors. CAS No. 1448671-31-5. Pack Sizes: 5mg. Product ID: S7339. Formula: C21H24F3N5O5S. Smiles: CC1=C(C(=NN1)C(F)(F)F)CC2=C(C3=C(S2)N(C(=O)N(C3=O)C)C(C)C)C(=O)N4CC(CO4)(C)O. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| AZD4547 (Fexagratinib) | Fexagratinib (AZD4547,ABSK 091) is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM in cell-free assays, weaker activity against FGFR4, VEGFR2(KDR), and little activity observed against IGFR, CDK2, and p38. Phase 2/3. Group: Inhibitors. Alternative Names: ABSK 091. CAS No. 1035270-39-3. Pack Sizes: 5mg. Product ID: S2801. Formula: C26H33N5O3. Smiles: CC1CN(CC(N1)C)C2=CC=C(C=C2)C(=O)NC3=NNC(=C3)CCC4=CC(=CC(=C4)OC)OC. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| AZD4573 | AZD4573 is a potent inhibitor of CDK9 (IC50 of 1/2 = 16 min) and high selectivity versus other kinases, including other CDK family kinases. Group: Inhibitors. CAS No. 2057509-72-3. Pack Sizes: 2mg. Product ID: S8719. Formula: C22H28ClN5O2. Smiles: CC(=O)NC1CCCC(C1)C(=O)NC2=NC=C(C(=C2)C3=C4CC(CN4N=C3)(C)C)Cl. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| AZD5305 (Saruparib) | Saruparib (AZD5305) is a highly selective and potent inhibitor of PARP1 with an IC50 of 3 nM in wild-type A549 lung cancer cells. AZD5305 shows no or minimal growth inhibitory effects in other cells (IC50s >10μM). Group: Inhibitors. CAS No. 2589531-76-8. Pack Sizes: 5mg. Product ID: S9875. Formula: C22H26N6O2. Storage Conditions: 3 years -20°C powder. | United States; Europe |
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