Selleck Chemicals - Products
United States; Europe
Selleck Chemicals supplies bioactive small molecules, inhibitors, compound libraries, antibodies, natural products and related research reagents for life science research.
| Product | Description | |
|---|---|---|
| Capsaicin(Vanilloid) | Capsaicin(Vanilloid) is an active component of chili peppers, which are plants belonging to the genus Capsicum.Capsaici is a TRPV1 agonist with an EC50 of 0.29 μM in HEK293 cells.Capsaicin is a mixture of Capsaicin and Dihydrocapsaicin. Group: Inhibitors. CAS No. 404-86-4. Pack Sizes: 50mg. Product ID: S1990. Formula: C18H27NO3. Smiles: CC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| Carboplatin | Carboplatin, a derivative of CDDP, is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death and interfers with the cell's repair mechanism in A2780, SKOV-3, IGROV-1, and HX62 cells. It induces the formation of DNA interstrand crosslinks and DNA-protein crosslinks. Solutions are unstable and should be fresh-prepared.DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation. Group: Inhibitors. Alternative Names: NSC 241240, JM-8, CBDCA. CAS No. 41575-94-4. Pack Sizes: 50mg. Product ID: S1215. Formula: C6H12N2O4Pt. Smiles: C1CC(C1)(C(=O)O)C(=O)O.[NH2-].[NH2-].[Pt+2]. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Caspase1 Antibody [D17C3] | Caspase 1,Caspase-1,caspase-1 p10. Group: Antibodies. Alternative Names: Caspase 1,caspase-1 p10. Pack Sizes: 20ul. Product ID: F0461. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Caspase3 Antibody [F8M16] | Caspase 3,Caspase-3. Group: Antibodies. Alternative Names: Caspase-3. Pack Sizes: 20ul. Product ID: F1080. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Caspase-3 p12 Antibody [N15D21] | caspase-3 p11,Caspase-3 p12. Group: Antibodies. Alternative Names: CPP32, CASP3, Caspase-3, CASP-3, Apopain, Cysteine protease CPP32, Protein Yama, SREBP cleavage activity 1, CPP-32, SCA-1. CAS No. Pack Sizes: 20uL. Product ID: F2459. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Cathepsin B Antibody [F7N18] | Cathepsin B,Cathepsin B (G60). Group: Antibodies. Alternative Names: Cathepsin B,G60, CTSB. Pack Sizes: 20ul. Product ID: F0474. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Cathepsin D Antibody [P17C14] | Cathepsin D. Group: Antibodies. Alternative Names: Cathepsin D, CTSD. CAS No. Pack Sizes: 20uL. Product ID: F1610. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Caveolin-1 Antibody [C16P21] | Caveolin 1,Caveolin-1. Group: Antibodies. Alternative Names: Caveolin 1. Pack Sizes: 20ul. Product ID: F0224. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CBL0137 Hydrochloride | CBL0137 (CBLC137, Curaxin 137) HCl activates p53 and inhibits NF-κB with EC50s of 0.37 μM and 0.47 μM in the cell-based p53 and NF-kB reporter assays, respectively. It also inhibits histone chaperone FACT (facilitates chromatin transcription complex). Group: Inhibitors. Alternative Names: CBLC137 HCl, Curaxin 137 HCl. CAS No. 1197397-89-9. Pack Sizes: 5mg. Product ID: S8483. Formula: C21H24N2O2.HCl. Smiles: CC(C)NCCN1C2=C(C=C(C=C2)C(=O)C)C3=C1C=CC(=C3)C(=O)C.Cl. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| CC-5013 (Lenalidomide) | Lenalidomide is a TNF-α secretion inhibitor with IC50 of 13 nM in PBMCs. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide promotes cleaved caspase-3 expression and inhibit VEGF expression and induces apoptosis. Group: Inhibitors. Alternative Names: CC-5013. CAS No. 191732-72-6. Pack Sizes: 1g. Product ID: S1029. Formula: C13H13N3O3. Smiles: C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| CCCP (Carbonyl cyanide 3-chlorophenylhydrazone) | CCCP (Carbonyl cyanide m-chlorophenyl hydrazone, Carbonyl cyanide 3-chlorophenylhydrazone), an oxidative phosphorylation inhibitor, is a protonophore mitochondrial uncoupler that increases membrane permeability to protons, leading to a disruption in the mitochondrial membrane potential. Carbonyl cyanide 3-chlorophenylhydrazone (CCCP), the protonophore, can inhibits STING-mediated IFN-β production via disrupting mitochondrial membrane potential (MMP). Group: Inhibitors. Alternative Names: Carbonyl cyanide m-chlorophenyl hydrazone, Carbonyl cyanide 3-chlorophenylhydrazone. CAS No. 555-60-2. Pack Sizes: 25mg. Product ID: S6494. Formula: C9H5ClN4. Smiles: C1=CC(=CC(=C1)Cl)NN=C(C#N)C#N. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| CD163 Antibody [P12L8] | CD163 Antibody [P12L8]. Group: Antibodies. Pack Sizes: 20uL. Product ID: F1548. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CD206/MRC1 Antibody [K13P18] | CD206/MRC1 Antibody [K13P18]. Group: Antibodies. Alternative Names: Macrophage mannose receptor 1, MMR, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, Human mannose receptor (hMR), Macrophage mannose receptor 1-like protein 1, CD206, MRC1, CLEC13D, CLEC13DL, MRC1L1. CAS No. Pack Sizes: 20uL. Product ID: F4083. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CD31 (PECAM-1) Antibody [M18G16] | CD31,CD31 (PECAM-1),CD31 / PECAM-1,PECAM-1. Group: Antibodies. Alternative Names: CD31,PECAM-1. Pack Sizes: 20uL. Product ID: F0131. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CD38 inhibitor 1 (compound 78c) | CD38 inhibitor 1 (compound 78c, CD38-IN-78c, MDK-7553) is a potent inhibitor of CD38 with IC50 of 7.3 nM and 1.9 nM for human CD38 and mouse CD38, respetively. Group: Inhibitors. Alternative Names: CD38-IN-78c, MDK-7553. CAS No. 1700637-55-3. Pack Sizes: 5mg. Product ID: S8960. Formula: C22H27N3O3S. Smiles: CN1C2=C(C=C(C=C2)C3=CN=CS3)C(=CC1=O)NC4CCC(CC4)OCCOC. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| CD63 Antibody [N10M7] | CD63 Antibody [N10M7]. Group: Antibodies. CAS No. Pack Sizes: 20uL. Product ID: F0983. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CD68 Antibody [M20C19] | CD68,CD68/SR-D1. Group: Antibodies. Alternative Names: CD68, Macrosialin, Cd68. CAS No. Pack Sizes: 20uL. Product ID: F3794. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CD9 Antibody [J21F10] | CD9 Antibody [J21F10]. Group: Antibodies. Pack Sizes: 20ul. Product ID: F1178. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CDKN2A/p16INK4a Antibody [B12M16] | CDKN2A/p16,CDKN2A/p16INK4a,p16,p16 INK4A. Group: Antibodies. Alternative Names: CDKN2, MTS1, CDKN2A, Cyclin-dependent kinase inhibitor 2A, Cyclin-dependent kinase 4 inhibitor A, Multiple tumor suppressor 1, p16-INK4a, CDK4I, MTS-1, p16-INK4, p16INK4A. CAS No. Pack Sizes: 20uL. Product ID: F3773. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CDKN2A/p16INK4a Antibody [P15P14] | CDKN2A/p16,CDKN2A/p16INK4a,p16,p16 INK4A. Group: Antibodies. Alternative Names: CDKN2A/p16,p16 INK4A. Pack Sizes: 20uL. Product ID: F1180. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Celastrol (Tripterine) | Celastrol is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM. Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway. Celastrol inhibits dopaminergic neuronal death of Parkinson's disease through activating mitophagy. Group: Inhibitors. Alternative Names: NSC 70931, Tripterine. CAS No. 34157-83-0. Pack Sizes: 10mg. Product ID: S1290. Formula: C29H38O4. Smiles: CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Celecoxib (SC-58635) | Celecoxib is a selective COX-2 inhibitor with IC50 of 40 nM in Sf9 cells. Group: Inhibitors. Alternative Names: SC 58635. CAS No. 169590-42-5. Pack Sizes: 100mg. Product ID: S1261. Formula: C17H14F3N3O2S. Smiles: CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Cell Counting Kit-8 (CCK-8) | The Bimake Cell Counting Kit-8 (CCK-8) is a fluorescent assay for the determination of cell viability in vitro. Results are obtained in only 3 steps: addition, incubation and reading. Group: Kits. Pack Sizes: 5 mL (500 rxns). Product ID: B34302. Storage Conditions: 3 years-20°C powder 2 years-80°C in solvent. | United States; Europe |
| Cell Counting Kit-8 (CCK-8) | The Bimake Cell Counting Kit-8 (CCK-8) is a fluorescent assay for the determination of cell viability in vitro. Results are obtained in only 3 steps: addition, incubation and reading. Group: Kits. Pack Sizes: 25 mL (2500 rxns). Product ID: B34304. Storage Conditions: 3 years-20°C powder 2 years-80°C in solvent. | United States; Europe |
| Ceralasertib (AZD6738) | Ceralasertib (AZD6738) is an orally active, and selective ATR kinase inhibitor with IC50 of 1 nM. Phase 1/2. Group: Inhibitors. CAS No. 1352226-88-0. Pack Sizes: 5mg. Product ID: S7693. Formula: C20H24N6O2S. Smiles: CC1COCCN1C2=NC(=NC(=C2)C3(CC3)S(=N)(=O)C)C4=C5C=CNC5=NC=C4. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Cetuximab (anti-EGFR) | Cetuximab, a novel molecular-targeted agent,is an inhibitor of EGFR monoclonal humanized antibody interacting with the extracellular binding site of EGFR to block ligand stimulation. MW?145.781 KD. Group: Antibodies. Alternative Names: C225. CAS No. 205923-56-4. Pack Sizes: 1mg. Product ID: A2000. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| c-Fos Antibody [B8E19] | c-Fos Antibody [B8E19]. Group: Antibodies. Alternative Names: Protein c-Fos; Cellular oncogene fos; Fos proto-oncogene, AP-1 transcription factor subunit; G0/G1 switch regulatory protein 7; Proto-oncogene c-Fos; Transcription factor AP-1 subunit c-Fos; FOS; G0S7. CAS No. Pack Sizes: 20uL. Product ID: F4131. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CFSE (CFDA-SE) | Carboxyfluorescein succinimidyl ester (CFSE, 5(6)-Carboxyfluorescein diacetate succinimidyl ester, CFDA-SE, 5(6)-CFDA N-succinmidyl ester) is a fluorescent cell staining dye. CFSE is frequently used in cell proliferation assay and motility assays. CFSE is cell permeable and covalently couples, via its succinimidyl group, to intracellular molecules, notably, to intracellular lysine residues and other amine sources. Group: Inhibitors. Alternative Names: Carboxyfluorescein succinimidyl ester, 5(6)-Carboxyfluorescein diacetate succinimidyl ester, CFDA-SE, 5(6)-CFDA N-succinmidyl ester. CAS No. 150347-59-4. Pack Sizes: 10mg. Product ID: S8269. Formula: C29H19NO11. Smiles: CC(=O)OC1=CC=C2C(=C1)OC3=C(C=CC(=C3)OC(C)=O)C24OC(=O)C5=CC(=CC=C45)C(=O)ON6C(=O)CCC6=O.CC(=O)OC7=CC=C8C(=C7)OC9=C(C=CC(=C9)OC(C)=O)C8%10OC(=O)C%11=CC=C(C=C%10%11)C(=O)ON%12C(=O)CCC%12=O. Storage Conditions: 3 years -20°C(in the dark) powder. | United States; Europe |
| CFTRinh-172 | CFTRinh-172 (CFTR inhibitor 172) is a voltage-independent, selective CFTR inhibitor with Ki of 300 nM, showing no effects on MDR1, ATP-sensitive K+ channels, or a series of other transporters. Group: Inhibitors. Alternative Names: CFTR inhibitor 172. CAS No. 307510-92-5. Pack Sizes: 10mg. Product ID: S7139. Formula: C18H10F3NO3S2. Smiles: C1=CC(=CC(=C1)N2C(=O)C(=CC3=CC=C(C=C3)C(=O)O)SC2=S)C(F)(F)F. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| cGAS Antibody [L20A17] | cGAS Antibody [L20A17]. Group: Antibodies. Alternative Names: Cyclic GMP-AMP synthase; cGAMP synthase; cGAS; m-cGAS; 2'3'-cGAMP synthase; Mab-21 domain-containing protein 1; Cgas; Mb21d1. Pack Sizes: 20uL. Product ID: F4205. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CH-223191 | CH-223191 is a potent and specific aryl hydrocarbon receptor (AhR) antagonist with IC50 of 30 nM. Group: Inhibitors. CAS No. 301326-22-7. Pack Sizes: 10mg. Product ID: S7711. Formula: C19H19N5O. Smiles: CC1=CC=CC=C1N=NC2=CC(=C(C=C2)NC(=O)C3=CC=NN3C)C. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Chaetocin | Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively. Chaetocin is an anticancer agent and inhibitor of thioredoxin reductase (TrxR). Group: Inhibitors. CAS No. 28097-03-2. Pack Sizes: 1mg. Product ID: S8068. Formula: C30H28N6O6S4. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| CHIR-98014 | CHIR-98014 (CT98014) is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2. Group: Inhibitors. Alternative Names: CT98014. CAS No. 252935-94-7. Pack Sizes: 5mg. Product ID: S2745. Formula: C20H17Cl2N9O2. Smiles: C1=CC(=C(C=C1Cl)Cl)C2=NC(=NC=C2N3C=CN=C3)NCCNC4=NC(=C(C=C4)[N+](=O)[O-])N. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| CHIR-99021 (Laduviglusib) | Laduviglusib (CHIR-99021, CT99021) is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively. CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3β compared to CDKs. CHIR99021 functions as a Wnt/β-catenin activator and induces autophagy. Group: Inhibitors. Alternative Names: CT99021. CAS No. 252917-06-9. Pack Sizes: 2mg. Product ID: S1263. Formula: C22H18Cl2N8. Smiles: CC1=CN=C(N1)C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)Cl)NCCNC4=NC=C(C=C4)C#N. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Chloroquine | Chloroquine is an antimalarial drug and autophagy / lysosome inhibitor. Chloroquine also suppresses Toll-like receptor-9 (TLR9) protein expression. Chloroquine is highly effective agianst SARS-CoV-2 (COVID-19) infection with EC50 of 1.13 μM in Vero E6 cells. Chloroquine has anti-HIV-1 activity. Group: Inhibitors. Alternative Names: NSC-187208, CHQ, CQ. CAS No. 54-05-7. Pack Sizes: 100mg. Product ID: S6999. Formula: C18H26ClN3. Smiles: CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| Chloroquine diphosphate | Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. Chloroquine is also an inhibitor of toll-like receptors (TLRs). Group: Inhibitors. CAS No. 50-63-5. Pack Sizes: 50mg. Product ID: S4157. Formula: C18H26ClN3.2H3O4P. Smiles: CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl.OP(=O)(O)O.OP(=O)(O)O. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Chlorpromazine (CPZ) | Chlorpromazine (CPZ) is a low-potency typical antipsychotic agent that is used to treat psychotic disorders such as schizophrenia. Chlorpromazine (CPZ) inhibits 5-HT(2A) receptor and dopamine D2 in vitro. Chlorpromazine (CPZ) also inhibits sodium channel and blocks HERG potassium channels with IC50 of 21.6 μM. Group: Inhibitors. Alternative Names: CPZ. CAS No. 50-53-3. Pack Sizes: 25mg. Product ID: S5749. Formula: C17H19ClN2S. Smiles: CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| Cholesterol | Cholesterol(Cholesterin) is the principal sterol of all higher animals required to build and maintain membranes. Group: Inhibitors. Alternative Names: Cholesterin. CAS No. 57-88-5. Pack Sizes: 50mg. Product ID: S4154. Formula: C27H46O. Smiles: CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| CHOP Antibody [C21N8] | CHOP,DDIT3,DDIT3/GADD153 / CHOP,GADD153 / CHOP. Group: Antibodies. Alternative Names: C/EBP homoologous protein 10; C/EBP zeta; C/EBP-homologous protein; C/EBP-homologous protein 10; CCAAT / enhancer-binding protein homologous protein; CHOP; CHOP-10; DDIT-3; MGC4154; CEBPZ; CHOP; CHOP-10; CHOP10; DDIT3; GADD153. CAS No. Pack Sizes: 20uL. Product ID: F2691. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Cilengitide (EMD 121974) | Cilengitide (EMD 121974, EMD-12192, EMD-85189, NSC-707544) is a potent and selective inhibitor of the integrins ανβ3 and ανβ5 with IC50 of 4 and 79 nM, respectively. Group: Inhibitors. Alternative Names: EMD 121974, EMD-12192, EMD-85189, NSC-707544. CAS No. 188968-51-6. Pack Sizes: 5mg. Product ID: S6387. Formula: C27H40N8O7. Smiles: CC(C)C1N(C)C(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(CCCNC(N)=N)NC1=O. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| Cisplatin | Cisplatin is an inorganic platinum complex, which is able to inhibit DNA synthesis by conforming DNA adducts in tumor cells. Cisplatin activates ferroptosis and induces autophagy.Solutions are unstable and should be fresh-prepared.DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation. Group: Inhibitors. Alternative Names: NSC 119875, Cisplatinum, cis-diamminedichloroplatinum II, CDDP, cis DDP, DDP. CAS No. 15663-27-1. Pack Sizes: 10g. Product ID: S1166. Formula: Cl2H6N2Pt. Smiles: [NH2-].[NH2-].Cl[Pt+2]Cl. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| c-Jun Antibody [B18M18] | c-Jun Antibody [B18M18]. Group: Antibodies. Pack Sizes: 20ul. Product ID: F0168. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CK-666 | CK-666 is an inhibitor of the actin-related protein 2/3 (Arp2/3) complex with IC50 of 17 μM and 5 μM for BtArp2/3 complex and SpArp2/3 complex, respectively. Group: Inhibitors. CAS No. 442633-00-3. Pack Sizes: 5mg. Product ID: S7690. Formula: C18H17FN2O. Smiles: CC1=C(CCNC(=O)C2=CC=CC=C2F)C3=C([NH]1)C=CC=C3. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| Cl-amidine | Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. Cl-amidine induces apoptosis. Group: Inhibitors. CAS No. 1043444-18-3. Pack Sizes: 5mg. Product ID: S8141. Formula: C14H19ClN4O2.C2HF3O2. Smiles: C1=CC=C(C=C1)C(=O)NC(CCCN=C(CCl)N)C(=O)N.C(=O)(C(F)(F)F)O. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Cleaved Caspase3 (Asp175) Antibody [P20N20] | Active Caspase-3,Caspase 3, Active,Cleaved Caspase-3,Cleaved Caspase-3 (Asp175). Group: Antibodies. Alternative Names: Active Caspase-3,Caspase 3,Cleaved Caspase-3,Cleaved Caspase-3 (Asp175). Pack Sizes: 20uL. Product ID: F0135. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Cleaved Caspase9 (Asp315) Antibody [L17L24] | Cleaved Caspase9 (Asp315) Antibody [L17L24]. Group: Antibodies. Pack Sizes: 20ul. Product ID: F0326. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Cleaved Notch1 (Val1744) Antibody [H7M6] | Cleaved Notch1 (Val1744) Antibody [H7M6]. Group: Antibodies. Pack Sizes: 20ul. Product ID: F0277. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Cleaved PARP (Asp214) Antibody [M18N4] | Cleaved PARP (Asp214),Cleaved-PARP (Asp214). Group: Antibodies. Pack Sizes: 20ul. Product ID: F0136. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Clemastine (HS-592) Fumarate | Clemastine fumarate is a selective histamine H1 receptor antagonist with IC50 of 3 nM. Clemastine stimulates autophagy via mTOR pathway. Group: Inhibitors. Alternative Names: HS-592 fumarate, Meclastine fumarate. CAS No. 14976-57-9. Pack Sizes: 50mg. Product ID: S1847. Formula: C21H26ClNO.C4H4O4. Smiles: CC(C1=CC=CC=C1)(C2=CC=C(C=C2)Cl)OCCC3CCCN3C.C(=CC(=O)O)C(=O)O. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Clozapine N-oxide (CNO chemical) | CNO (Clozapine N-oxide) is a metabolite of Clozapine (GLXC-06516) and an agonist of human muscarinic designer receptors (Designer Receptors Exclusively Activated by Designer Drugs, DREADDs). Clozapine is a potent dopamine (DA) antagonist and a selective muscarinic M4 receptor agonist.Solutions are unstable and should be fresh-prepared. Group: Inhibitors. CAS No. 34233-69-7. Pack Sizes: 5mg. Product ID: S6887. Formula: C18H19ClN4O. Smiles: C[N+]1([O-])CCN(CC1)C2=NC3=C(NC4=CC=CC=C24)C=CC(=C3)Cl. | United States; Europe |
| CMC-Na | CMC-Na (Sodium carboxymethyl cellulose) is one of the important modified cellulose, a water-soluble cellulose, which is widely used in many application of food, pharmaceuticals, detergent, paper coating, dispersing agent, and others. Its addition possibly increases the hydrogenation and dehydrogenation features of Magnesium. Group: Inhibitors. Alternative Names: Sodium carboxymethyl cellulose. CAS No. 9004-32-4. Pack Sizes: 5g. Product ID: S6703. Smiles: CC(=O)O.C(C(C(C(C(C=O)O)O)O)O)O.[Na]. | United States; Europe |
| c-Myc/N-Myc Antibody [G7K4] | Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, bHLHe39, Proto-oncogene c-Myc, Transcription factor p64, myc, N-myc proto-oncogene protein, Class E basic helix-loop-helix protein 37, bHLHe37, MYCN, BHLHE37, NMYC. Group: Antibodies. Alternative Names: bHLHe39, bHLHe37. Pack Sizes: 20uL. Product ID: F2664. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Cobimetinib (GDC-0973) | Cobimetinib (GDC-0973, RG7420) is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, and showing no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases. Cobimetinib induces apoptosis. Phase 3. Group: Inhibitors. Alternative Names: RG7420,XL518. CAS No. 934660-93-2. Pack Sizes: 5mg. Product ID: S8041. Formula: C21H21F3IN3O2. Smiles: C1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| COL1A1 Antibody [B17N21] | COL1A1,Collagen I alpha 1. Group: Antibodies. Alternative Names: Collagen I α 1. Pack Sizes: 20ul. Product ID: F1228. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Colchicine | Colchicine is a microtubule polymerization inhibitor with an IC50 of 3 nM. Group: Inhibitors. Alternative Names: Colchineos, Colchisol, Colcin,NSC 757. CAS No. 64-86-8. Pack Sizes: 1g. Product ID: S2284. Formula: C22H25NO6. Smiles: CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Colivelin | Colivelin (CLN) is a brain-penetrant neuroprotective peptide with potent long-term capacity against Aβ deposition, neuronal apoptosis, and synaptic plasticity deficits in neurodegenerative disease. Colivelin is an activator of STAT3. Group: Inhibitors. Alternative Names: CLN. CAS No. 867021-83-8. Pack Sizes: 5mg. Product ID: S9664. Formula: C119H206N32O35. Smiles: CCC(C)C(C(=O)NC(CC(=O)O)C(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)O)NC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C(C(C)O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(C)NC(=O)CNC(=O)C(C)NC(=O)C2CCCN2C(=O)C(C)NC(=O)C3CCCN3C(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CO)N. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| Corn Oil | Corn oil is a refined vegetable oil used as a delivery vehicle for fat-soluble compounds, including toxins. It is also used in the delivery of tamoxifen (TAM) in mice, curcumin in rats, and [3H]retinol in mice. Group: Inhibitors. CAS No. 8001-30-7. Pack Sizes: 100mL. Product ID: S6701. Storage Conditions: 2 years 4°C(in the dark) liquid. | United States; Europe |
| COX2 / Cyclooxygenase 2 Antibody [N14E22] | Cox2,Cox-2,COX2 / Cyclooxygenase 2. Group: Antibodies. Alternative Names: Prostaglandin G/H synthase 2, PHS II, Prostaglandin H2 synthase 2, Prostaglandin-endoperoxide synthase 2, PGH synthase 2, PGHS-2, PTGS2, Cyclooxygenase-2, COX-2, COX2. Pack Sizes: 20ul. Product ID: F0327. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| COX IV Antibody [A4F21] | COX IV Antibody [A4F21]. Group: Antibodies. Alternative Names: Cytochrome c oxidase subunit 4 isoform 1; mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1; COX4I1; COX4. Pack Sizes: 20uL. Product ID: F4133. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CP-673451 | CP-673451 is a selective inhibitor of PDGFRα/β with IC50 of 10 nM/1 nM in cell-free assays, exhibits >450-fold selectivity over other angiogenic receptors, has antiangiogenic and antitumor activity. Group: Inhibitors. CAS No. 343787-29-1. Pack Sizes: 5mg. Product ID: S1536. Formula: C24H27N5O2. Smiles: COCCOC1=CC2=C(C=C1)N(C=N2)C3=NC4=C(C=CC=C4N5CCC(CC5)N)C=C3. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| CP-690550 (Tofacitinib) Citrate | Tofacitinib citrate (CP-690550, Tasocitinib) is a novel JAK inhibitor with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively. It also has anti-infection activity. Group: Inhibitors. Alternative Names: Tasocitinib Citrate,CP-690550. CAS No. 540737-29-9. Pack Sizes: 10mg. Product ID: S5001. Formula: C16H20N6O.C6H8O7. Smiles: CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N.C(C(=O)O)C(CC(=O)O)(C(=O)O)O. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| CPI-613 (Devimistat) | Devimistat (CPI-613), a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase in NCI-H460 cell line, disrupts tumor cell mitochondrial metabolism. CPI-613 induces apoptosis in pancreatic cancer cells. Phase 2. Group: Inhibitors. CAS No. 95809-78-2. Pack Sizes: 5mg. Product ID: S2776. Formula: C22H28O2S2. Smiles: C1=CC=C(C=C1)CSCCC(CCCCC(=O)O)SCC2=CC=CC=C2. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| CPT1A Antibody [B8M12] | CPT1A Antibody [B8M12]. Group: Antibodies. Alternative Names: CPT1, CPT1A, CPT1-L, Carnitine palmitoyltransferase 1A, Succinyltransferase CPT1A, CPT I, CPTI-L. Pack Sizes: 20uL. Product ID: F3751. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CREB Antibody [A17C9] | CREB,CREB1,CREB-1. Group: Antibodies. Alternative Names: CREB,CREB-1. CAS No. Pack Sizes: 20ul. Product ID: F0133. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Cremophor EL | Cremophor EL, a polyethoxylated surfactant, is a formulation vehicle used for various poorly-water soluble drugs, including the anticancer agent paclitaxel (Taxol). Cremophor EL is used in severe anaphylactoid hypersensitivity reactions, hyperlipidaemia, abnormal lipoprotein patterns, aggregation of erythrocytes and peripheral neuropathy. Group: Inhibitors. Alternative Names: CrEL. CAS No. 61791-12-6. Pack Sizes: 100g. Product ID: S6828. Smiles: C(C(CCl)OC(=O)N)Cl. Storage Conditions: 2 years -20°C(in the dark) liquid. | United States; Europe |
| Curcumin (Diferuloylmethane) | Curcumin (Diferuloylmethane, Natural Yellow 3, Turmeric yellow) is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase (IC50~25 μM) and Histone deacetylase (HDAC); activates Nrf2 pathway and supresses the activation of NF-κB. Curcumin induces mitophagy, autophagy, apoptosis, and cell cycle arrest with antitumor activity. Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death. Curcumin exhibits anti-infective properties against various human pathogens like the influenza virus, hepatitis C virus, HIV and so on. Group: Inhibitors. Alternative Names: Diferuloylmethane, Natural Yellow 3, Turmeric yellow. CAS No. 458-37-7. Pack Sizes: 50mg. Product ID: S1848. Formula: C21H20O6. Smiles: COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| CX-5461 (Pidnarulex) | Pidnarulex (CX-5461) is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM in HCT-116, A375, and MIA PaCa-2 cells, has no effect on Pol II, and possesses 250- to 300-fold selectivity for inhibition of rRNA transcription versus DNA replication and protein translation. Group: Inhibitors. CAS No. 1138549-36-6. Pack Sizes: 5mg. Product ID: S2684. Formula: C27H27N7O2S. Smiles: CC1=CN=C(C=N1)CNC(=O)C2=C3N(C4=CC=CC=C4S3)C5=C(C2=O)C=CC(=N5)N6CCCN(CC6)C. Storage Conditions: 3 years-20°C(in the dark) powder. | United States; Europe |
| Cyclin A2 Antibody [H5M13] | Cyclin-dependent kinase 2, Cell division protein kinase 2, p33 protein kinase, CDK2, CDKN2, Cyclin-A2, Cyclin-A, CCNA2, CCN1, CCNA, Cyclin-dependent kinase 1, CDK1, Cell division control protein 2 homolog, Cell division, protein kinase 1, p34 protein kinase, CDC2, CDC28A, CDKN1, P34CDC2. Group: Antibodies. Alternative Names: CDKN2, Cyclin-A2, CDC2, CDC28A. Pack Sizes: 20ul. Product ID: F1033. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Cyclin D1 Antibody [L2G10] | Cyclin D,Cyclin D1. Group: Antibodies. Alternative Names: Cyclin D,Cyclin D1. Pack Sizes: 20uL. Product ID: F0137. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Cycloheximide | Cycloheximide, an antifungal antibiotic, is an eukaryote protein synthesis inhibitor with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively. Cycloheximide suppresses ferroptosis and inhibits autophagy.Cycloheximide (NSC-185) can be used to induce animal models of Dysmnesia.Solutions are unstable and should be fresh-prepared.This product is a hazardous chemical (acute toxicity / flammable / skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing. Group: Inhibitors. Alternative Names: NSC-185, Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80. CAS No. 66-81-9. Pack Sizes: 200mg. Product ID: S7418. Formula: C15H23NO4. Smiles: CC1CC(C(=O)C(C1)C(CC2CC(=O)NC(=O)C2)O)C. Storage Conditions: 3 years -20°C(in the dark) powder. | United States; Europe |
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