MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Hippuric acid-d5 | Hippuric acid-d5 is the deuterium labeled Hippuric acid. Hippuric Acid (2-Benzamidoacetic acid), an acyl glycine produced by the conjugation of benzoic acid and glycine, is a normal component in urine as a metabolite of aromatic compounds from food. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Benzamidoacetic acid-d5. CAS No. 53518-98-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-W016562S. |  |
| Hippuric acid (Standard) | Hippuric acid (Standard) is the analytical standard of Hippuric acid. This product is intended for research and analytical applications. Hippuric Acid is an orally active metabolite. Hippuric Acid can be produced by intestinal microorganisms from the metabolism of polyphenols, benzoic acid. Hippuric Acid decreases NRF2, MMP9 and leads to ROS accumulation. Hippuric Acid activates TGFβ/SMAD signaling. Hippuric Acid improves hyperuricemia and colitis. Hippuric Acid can also be used in cardiovascular disease research[1][2][3][4].[5][6][7][8][9]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Benzoylglycine (Standard). CAS No. 495-69-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W016562R. | |
| Hippuryl-His-Leu-OH hydrate | Hippuryl-His-Leu-OH (N-Benzoyl-Gly-His-Leu) hydrate is a specific substrate for angiotensin-converting enzyme ACE I and is a molecular tool used for ACE activity detection in in vitro experiments. Hippuryl-His-Leu-OH hydrate is hydrolyzed by ACE through competitive binding. Under ACE catalysis, Hippuryl-His-Leu-OH hydrate undergoes hydrolysis to produce hippuric acid (HA). The amount of HA produced can be used to quantitatively assess ACE activity or screen for ACE inhibitors. The His-Leu released from Hippuryl-His-Leu-OH hydrate can also react with o-phthalaldehyde or Fluorescamine (HY-D0715) for fluorescence detection. Hippuryl-His-Leu-OH hydrate can be applied to the in vitro screening of ACE inhibitors for hypertension and cardiovascular diseases, and is also used in the study of changes in ACE activity during physiological and pathological processes such as renal compensatory hypertrophy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Benzoyl-Gly-His-Leu hydrate. CAS No. 207386-83-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-137875. | |
| HIPS probe-1 | HIPS probe-1 (Compound 1) is a click chemistry reagent containing a alkyne group. HIPS probe-1 can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. HIPS probe-1 can be used as a chemical probe to specifically recognize and label aldehyde functional groups in DNA, especially abasic sites (AP sites) for DNA damage research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2490429-83-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-176846. | |
| Hirsutine | Hirsutine, an indole alkaloid of Uncaria rhynchophylla, exhibits anti-cancer activity. Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 7729-23-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-N2193. | |
| Hirugen | Hirugen is a derivative of hirudin, an anticoagulant protein found in leeches[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 121822-23-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2023. | |
| His 11 | His11 is consists of a contiguous series of amino acid residues. His11 can be used as a tag peptide[1]. Uses: Scientific research. Category: Peptides. CAS No. 620927-23-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5758. | |
| His-[D-2-ME-Trp]-Ala | His-[D-2-ME-Trp]-Ala is a fragment of the growth hormone hexarelin. Uses: Scientific research. Category: Signaling pathways. CAS No. 3026595-80-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1460. | |
| Hispidin | Hispidin, a PKC inhibitor and a phenolic compound can be found in Phellinus linteus, has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. CAS No. 555-55-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100618. | |
| Hispidulin | Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC50 of 2.71 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dinatin. CAS No. 1447-88-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N1950. | |
| Hispolon | Hispolon, a polyphenol, can be isolated from Phellinus linteus. Hispolon possesses anticancer, antidiabetic, antioxidant, antiviral, hepatoprotective, anti-diabetic, and anti-inflammatory activities[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 173933-40-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150521. | |
| His-Pro | His-Pro (Histidyl-proline) is a dipeptide consisting of histidyl and proline[1]. Uses: Scientific research. Category: Peptides. Alternative Names: Histidyl-proline; H-His-Pro-OH. CAS No. 20930-58-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-111659. | |
| Histamine | Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Ergamine. CAS No. 51-45-6. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g. Product ID: HY-B1204. | |
| Histamine-α,α,β,β-d4 dihydrochloride | Histamine-α,α,β,β-d4 (dihydrochloride) is the deuterium labeled Histamine. Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ergamine-α,α,β,β-d4 dihydrochloride. CAS No. 344299-48-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg. Product ID: HY-B1204S. | |
| Histamine dihydrochloride | Histamine dihydrochloride is the agonist for histamine receptor and a vasodilator. Histamine dihydrochloride is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine dihydrochloride affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine dihydrochloride can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Induced disease models products. CAS No. 56-92-8. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 5 g; 10 g; 25 g. Product ID: HY-B0722. | |
| Histatin-3 TFA | Histatin-3 TFA, a 32 amino acid peptide, possesses powerful antimicrobial properties. Histatin-3 TFA behaves as a substrate for proprotein convertase 1 (PC1), being cleaved by this endoprotease primarily at a site carboxy terminal to the single Arg25 residue (HRGYR decrease SN). Histatin-3 TFA is a moderately potent, reversible and competitive inhibitor of the furin-mediated cleavage of the pentapeptide pGlu-Arg-Thr-Lys-Arg-MCA fluorogenic substrate, with an estimated inhibition constant Ki of 1.98 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 112844-49-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5272. | |
| Histone Acetyltransferase Inhibitor II | Histone Acetyltransferase Inhibitor II (compound 2c) is a potent, selective and cell permeable p300 histone acetyltransferase inhibitor, with an IC50 of 5 μM. Histone Acetyltransferase Inhibitor II shows anti-acetylase activity in mammalian cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 932749-62-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100734. | |
| Histone H1-derived Peptide | Histone H1-derived Peptide is a phosphopeptide and the peptide substrates containes a sequence in accordance with the optimal recognition motif for CDK, can be used to detecting CDK1-cyclinB1 enzyme activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 889112-06-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2480. | |
| Histone H3 (1-21) | Histone H3 (1-21), derived from Histone H3 1-21 amino acids, is usually used as a substrate for methyltransferase (Histone 3 K4 and K9) and acetyltransferase (Histone 3 K9 and K14) assays[1]. Uses: Scientific research. Category: Peptides. CAS No. 873215-29-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2552. | |
| Histrelin acetate | Histrelin acetate, a GnRH analogue, is a GnRH Receptor agonist. Histrelin acetate increases serum luteinising hormone (LH), follicle stimulating hormone (FSH) and testosterone levels. Histrelin acetate can be used in the research of prostate cancer, endometriosis[1][2][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 220810-26-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0056A. | |
| HIV-1 TAT (48-60) | HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used to deliver exogenous macromolecules into cells in a non-disruptive way. Uses: Scientific research. Category: Signaling pathways. CAS No. 220408-24-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1491. | |
| HJ445A | HJ445A is a potent MYOF inhibitor and binds to the MYOF-C2D domain with a KD of 0.17 μM. HJ445A potently repressed the proliferation of gastric cancer cells with IC50 values of 0.16 and 0.14 μM in MGC803 and MKN45, respectively. HJ445A demonstrates superior antitumor efficacy in vivo and can be used for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3032441-59-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163084. | |
| HJB97 | HJB97 is a high-affinity BET inhibitor with Ki values of 0.9 nM (BRD2 BD1), 0.27 nM (BRD2 BD2), 0.18 nM (BRD3 BD1), 0.21 nM (BRD3 BD2), 0.5 nM (BRD4 BD1), and 1.0 nM (BRD4 BD2)[1]. HJB97 can serve as a ligand for target protein (Ligands for Target Protein for PROTAC) for the development of PROTAC BET degraders with antitumor activity[1]. HJB97 can be used for the synthesis of BETd-260 (HY-101519). Uses: Scientific research. Category: Signaling pathways. CAS No. 2093391-24-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112429. | |
| HJC0152 | HJC0152 is a signal transducers and activators of transcription 3 (STAT3) inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 1420290-99-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100602. | |
| HK-2-IN-1 | HK-2-IN-1 is a Hexokinase 2 (HK-2) inhibitor. HK-2-IN-1 exhibits a non-activating effect on human recombinant HK-2 enzyme. HK-2-IN-1 has anti-tumor activity, affecting immune cells in the tumor microenvironment. HK-2-IN-1 has immunomodulatory effects and is potentially useful in the study of cancers such as colon cancer, liver cancer, and breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3114833-48-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-175035. | |
| HKB99 | HKB99 is an allosteric inhibitor of phosphoglycerate mutase 1 (PGAM1). HKB99 induces apoptosis. HKB99 inhibits the formation of invasive pseudopodia and inhibits migration. HKB99 increases the oxidative stress, activates JNK/c-Jun and suppresses AKT and ERK. HKB99 can be used for the research of non-small-cell lung cancer (NSCLC)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2414908-90-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148510. | |
| HKGreen-4I | HKGreen-4I is a highly sensitive green fluorescent probe for the specific detection of ONOO- in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1448821-82-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1148. | |
| HKI-357 | HKI-357 is an irreversible dual inhibitor of EGFR and ERBB2 with IC50s of 34 nM and 33 nM, respectively. HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 848133-17-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103443. | |
| HKOCl-3 | HKOCl-3 is a highly sensitive and selective fluorescent probe for detecting hypochlorous acid.Ex: 490 nm; Em 527 nm[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2031170-80-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130025. | |
| HKOH-1r | HKOH-1r is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2138472-08-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-D1159. | |
| HKPao | HKPao (Hunter-killer peptide ao) is a biologically active peptide. HKPao (Hunter-killer peptide ao) has anti-obesity and anti-tumor pro-apoptotic activity to cause release of cytochrome c from vesicles[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hunter-killer peptide ao; Prohibitin-targeting peptide 1; prohibitin-TP01; Adipotide. CAS No. 859216-15-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3586. | |
| HKPerox-1 | HKPerox-1 is a highly sensitive green fluorescent probe for the specific detection of H2O2 in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2240163-05-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-130022. | |
| HKYK-0030 | HKYK-0030 is an inhibitor for MTDH-SND1 protein-protein interaction. HKYK-0030 exhibits inhibitory activity against cancer metastasis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2923054-94-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160801. | |
| HLCL-61 hydrochloride | HLCL-61 hydrochloride is a first-in-class inhibitor of protein arginine methyltransferase 5 (PRMT5). Uses: Scientific research. Category: Signaling pathways. CAS No. 1158279-20-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100025A. | |
| HLDA-221 | HLDA-221 is a non-covalent regulated induced proximity targeting chimeras (RIPTAC). The binding of HLDA-221 to BRD4-BD1 is significantly increased after pre-incubation with FKBP. HLDA-221 can be used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3077339-82-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156820. | |
| HLF1-11 | HLF1-11, a human lactoferrin-derived peptide, is a broad spectrum antimicrobial agent. HLF1-11 inhibits human MPO activity. HLF1-11 also directs GM-CSF-driven monocyte differentiation toward macrophages, and enhances immune responses[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 183623-03-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-106228. | |
| HLI373 dihydrochloride | HLI373 dihydrochloride is an efficacious Hdm2 inhibitor. HLI373 dihydrochloride inhibits the ubiquitin ligase activity of Hdm2. HLI373 dihydrochloride is effective in inducing apoptosis of several tumor cells that are sensitive to DNA-damaging agents[1]. Antimalarial activity[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1782531-99-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108640A. | |
| HLM006474 | HLM006474 is a pan E2F inhibitor, which inhibits E2F4 DNA-binding with an IC50 of 29.8 μM in A375 cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 353519-63-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16667. | |
| HLX-22 | HLX-22 is a humanized monoclonal antibody targeting HER2. HLX-22 induces apoptosis in HER2-overexpressing breast and gastric cancer cells combined with Trastuzumab (HY-P9907). HLX-22 has potent antitumor activity against advanced solid tumors[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AC101. CAS No. 2851060-90-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991588. | |
| HLY78 | HLY78, a Lycorine (HY-N0288) derivative, is a potent activator of the Wnt/β-catenin signaling pathway. HLY78 targets the DIX domain of Axin and promotes the Axin-LRP6 (lipoprotein receptor-related protein 6) association, thus promoting LRP6 phosphorylation and Wnt signal transduction. HLY78 can be used for subarachnoid hemorrhage (SAH) research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 854847-61-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122816. | |
| H-Lys(Z)-OtBu.HCl | H-Lys(Z)-OtBu.HCl is a lysine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5978-22-3. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 100 g; 500 g. Product ID: HY-W008029. | |
| HM03 | HM03 is a potent and selective HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) inhibitor. HM03 has anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 500565-15-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125974. | |
| HMBPP lithium | HMBPP lithium is an intermediate in isoprenoid biosynthesis that can be produced by bacteria and protozoa that use the non-mevalonate pathway for isoprenoid biosynthesis. HMBPP lithium is a ligand of the internal domain of BTN3A1 and is an activator for human Vγ9/Vδ2 T cells. HMBPP lithium exhibits phagostimulant property in mosquitos[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate lithium. CAS No. 396726-03-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-134891. | |
| HMBR | HMBR is an analogue with an additional methyl group on the aromatic ring and is non-fluorescent. HMBR conjugated with Y-FAST emits yellow fluorescence under blue light excitation (Ex= 419 nm; Em= 525-539 nm). HMBR is non-toxic to zebrafish embryos. HMBR has high cell permeability[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1287651-36-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1416. | |
| HMG499 | HMG499 is a potent and selective HMG-CoA reductase inhibitor with an IC50 of 0.41 μM. HMG499 can prevent statins-induced accumulation of HMGCR, reduce serum cholesterol levels and decrease atherosclerosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2416941-68-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114316. | |
| HMMNI-d3 | HMMNI-d3 (Hydroxy Dimetridazole-d3) is deuterium labeled HMMNI (HY-W008216). HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazol (HY-B1244). Dimetridazole is a nitroimidazole class agent that combats protozoan infections[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hydroxy Dimetridazole-d3. CAS No. 1015855-78-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W008216S. | |
| HMN-214 | HMN-214, an orally bioavailable proagent of HMN-176, is an inhibitor of polo-like kinase-1 (plk1), with antitumor activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IVX-214. CAS No. 173529-46-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12045. | |
| HMR 1556 | HMR 1556, a chromanol derivative, is a potent IKs blocker with IC50s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 223749-46-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106369. | |
| hnRNPK-IN-1 | hnRNPK-IN-1 is a heterogeneous nuclear ribonucleoprotein K (hnRNPK) binding ligand with Kd values of 4.6 μM and 2.6 μM measured with SPR and MST, respectively. hnRNPK-IN-1 inhibits c-myc transcription by disrupting the binding of hnRNPK and c-myc promoter. hnRNPK-IN-1 induces Hela cells apoptosis and has strongly anti-tumor activities[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2313528-04-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135691. | |
| HO-3867 | HO-3867 is a selective and potent STAT3 inhibitor and shows good antitumor activity. Uses: Scientific research. Category: Signaling pathways. CAS No. 1172133-28-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100453. | |
| HOAT | HOAT is a peptide bond-forming reagent. HOAT is utilized to affect formation of peptide bonds by coupling carboxylic acids with amines. HOAt is not mutagenic in the bacterial reverse mutation test[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 39968-33-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-Z0275. | |
| Hoechst 33258 | Hoechst 33258 is a blue to blue-green fluorescent live cell dye that can label DNA. Hoechst 33258 can specifically bind to the minor groove of DNA (and tends to bind to A/T-rich DNA), resulting in a significant increase in fluorescence intensity. Hoechst 33258 can cross the cell membrane and cause changes in DNA structure, such as G2/M phase arrest. Hoechst 33258 can bind to live or fixed cells, and the fluorescence intensity increases with increasing solution pH. As a DNA-specific probe, Hoechst 33258 can be used to detect DNA content, analyze cell cycle, etc. The excitation wavelength of Hoechst 33258 is 350-365 nm, and the emission wavelength is 460-490 nm[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: bisBenzimide H 33258; H 33258. CAS No. 23491-44-3. Pack Sizes: 50 mg; 100 mg. Product ID: HY-15558. | |
| Hoechst 33258 analog | Hoechst 33258 analog is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 258843-62-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15623. | |
| Hoechst 33258 trihydrochloride | Hoechst 33258 trihydrochloride is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: bisBenzimide H 33258 trihydrochloride; H 33258 trihydrochloride. CAS No. 23491-45-4. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-15558A. | |
| Hoechst 33342 | Hoechst 33342 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: bisBenzimide H 33342; HOE 33342. CAS No. 23491-52-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15559. | |
| Hoechst 33342 trihydrochloride | Hoechst 33342 trihydrochloride is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: bisBenzimide H 33342 trihydrochloride; HOE 33342 trihydrochloride. CAS No. 875756-97-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15559A. | |
| Hoechst 33342 trihydrochloride (solution) | Hoechst 33342 trihydrochloride (solution) is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].Solvent and Concentration: Sterile water: 10 mg/mL. Uses: Scientific research. Category: Signaling pathways. CAS No. 875756-97-1. Pack Sizes: 500 μL; 1 mL. Product ID: HY-DY1005. | |
| Hoechst 34580 tetrahydrochloride | Hoechst 34580 tetrahydrochloride is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HOE 34580 tetrahydrochloride. CAS No. 2310135-08-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15560B. | |
| Hoechst S 769121 | Hoechst S 769121 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Nuclear yellow. CAS No. 74681-68-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15619. | |
| HOIPIN-8 | HOIPIN-8 is a potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) with an IC50 of 11 nM. HOIPIN-8 is a HOIPIN-1 derivative with enhanced the potency by 255-fold in the petit-LUBAC inhibition, and 10-fold and 4-fold in the LUBAC- and TNF-α-mediated NF-κB activation, respectively than HOIPIN-1. HOIPIN-1 is a promising tool to explore the cellular functions of LUBAC[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2519537-70-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122882. | |
| Holo-Bovine Transferrin | Holo-Bovine Transferrin, a blood-plasma glycoprotein, is a target ligand for transferrin receptor. Holo-Bovine Transferrin can bind to and mediate the transport of iron[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 11096-37-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3267. | |
| Holomycin | Holomycin is an antibiotic with dithiolopyrrolone structure. Holomycin can inhibit bacterial RNA synthesis. Holomycin has antitumor activity. Holomycin can be used for the research of bacterial infection[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 488-04-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-135751. | |
| Homoeriodictyol | Homoeriodictyol is an orally active, bitter-tasting flavanone that can penetrate the blood-brain barrier. Homoeriodictyol enhances synaptic-related protein expression through NCOA4-mediated ferritin autophagy. Homoeriodictyol improves memory impairment in mice by inhibiting the NLRP3 inflammasome. Homoeriodictyol protects human endothelial cells from oxidative damage by activating Nrf2 and inhibiting mitochondrial dysfunction. Homoeriodictyol enhances ROS activity and induces apoptosis, exhibiting anticancer effects. Homoeriodictyol inhibits the survival and migration of androgen-resistant prostate cancer cells in vitro. Homoeriodictyol exerts antinociceptive activity in mice in vivo[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 446-71-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N8210. | |
| Homogentisic acid | Homogentisic acid is an orally active, blood-brain barrier-permeable amyloidogenic compound that functions as both an amyloid component and a pigment precursor. Accumulation of homogentisic acid downregulates tight junction proteins (such as claudin-5, occludin, ZO-1) and impairs blood-brain barrier integrity. Homogentisic acid and its oxidation product benzoquinone acetic acid not only induce the aggregation and fibrosis of multiple proteins (such as Aβ1-42, α-synuclein, SAA, Transthyretin (TTR), atrial natriuretic peptide), but also trigger oxidative stress, damage to the Wnt/β-catenin pathway, and neurotoxicity, leading to ochronosis pigment deposition and synaptic dysfunction. At specific concentrations, homogentisic acid exerts no cytotoxicity or genotoxicity on human peripheral blood lymphocytes, and even counteracts the genotoxicity induced by Irinotecan (HY-16562). Homogentisic acid serves as an important tool molecule for investigating the mechanisms of diseases including ochronosis, secondary amyloidosis, Alzheimer's disease, and colorectal cancer[1][2][3][4][5][6][7][8]. Uses: Scientific research. Category: Signaling pathways. CAS No. 451-13-8. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-113283. | |
| Homogentisic acid (Standard) | Homogentisic acid (Standard) is the analytical standard of Homogentisic acid. This product is intended for research and analytical applications. Homogentisic acid is a specific metabolite that accumulates in the urine and serum. Homogentisic acid can be used for diagnosis of alkaptonuria. Homogentisic acid is a phenolic acid[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 451-13-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113283R. | |
| Homoharringtonine | Homoharringtonine (Omacetaxine mepesuccinate;HHT) is a cytotoxic alkaloid with antitumor properties which acts by inhibiting translation elongation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Omacetaxine mepesuccinate; HHT. CAS No. 26833-87-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14944. | |
| Homopropargylglycine | Homopropargylglycine is a Methionine (HY-13694) analogue. Homopropargylglycine is incorporated at a suitable rate into newly synthesized proteins in a variety of systems, including mammalian cell culture. Homopropargylglycine can be used to identify old and new protein populations[1]. Homopropargylglycine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 215160-72-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W259668. | |
| Homo-PROTAC pVHL30 degrader 1 | Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC[1], consists of two ligands of von Hippel-Lindau. Uses: Scientific research. Category: Signaling pathways. CAS No. 2244684-49-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111593. | |
| Homosalate | Homosalate (Homomenthyl salicylate) is an organic compound used as a sunscreen to filter UV rays and protect the skin from sun damage. Homosalate has anti-inflammatory activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Homomenthyl salicylate. CAS No. 118-56-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0928. | |
| Homovanillic acid | Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vanilacetic acid. CAS No. 306-08-1. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 1 g. Product ID: HY-N0384. | |
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