MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) | Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, iNOS, and peroxynitrite (ONOO-) in the vascular wall, contributing to the reduction of blood pressure. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) can be used for in vitro cell culture[1][2][3]. This product is human serum albumin recombinantly expressed in an Escherichia coli expression system. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HSA (Cell culture grade, Endotoxin<0.125 EU/mg). CAS No. 70024-90-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-P1956A. |  |
| hUP1-IN-1 potassium | hUP1-IN-1 potassium (compound 6a) is a hUP1 inhibitor with Kii and Kis Urd of 375 and 635 nM. hUP1-IN-1 potassium showes inhibitory activities over hUP1 catalyzed reaction with 70% at 1 μM. hUP1-IN-1 potassium can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 118803-30-8. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-W017441A. | |
| (-)-Huperzine A | (-)-Huperzine A (Huperzine A) is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC50 of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimers disease[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Huperzine A. CAS No. 102518-79-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-17387. | |
| HuR degrader 2 | HuR degrader 2 (Compound 3) is a molecule glue, which targets RNA-binding protein Hu antigen R (HuR) and degrades 30% HuR at 0.1 μM. HuR degrader 2 inhibits the proliferation of cancer cell Colo-205, with IC50≤200 nM. HuR degrader 2 exhibits a high affinity with cereblon, with an HTRF ratio < 0.02[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3040301-46-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-163759. | |
| H-Val-Pro-Pro-OH TFA | H-Val-Pro-Pro-OH (TFA), a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 2828433-08-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-114161A. | |
| HX531 | HX531 is an orally active RXR antagonist with an IC50 of 18 nM. HX531 upregulates the p53-p21Cip1 pathway. HX531 abrogates the anti-apoptotic effect of t-RA. HX531 exerts anti-obesity, anti-diabetic and anti-melanoma activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 188844-34-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108521. | |
| HX600 | HX600 is a synthetic agonist for RXR (Retinoid X Receptor) heterodimer complex. HX600 prevents ischemia-induced neuronal damage. HX600 has orally bioactivity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 172705-89-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-120875. | |
| Hyaluronan-IN-1 | Hyaluronan-IN-1 (Pep-1) is a Hyaluronan inhibitor with a Kd value of 1.65 μM. Hyaluronan-IN-1 blocks CD44-dependent cell adhesion. Hyaluronan-IN-1 inhibits cell adhesion to hyaluronan substrates. Hyaluronan-IN-1 suppresses the development of contact hypersensitivity in mice by blocking the homing process of inflammatory cells to the skin. Hyaluronan-IN-1 also inhibits responses during the sensitization phase. Hyaluronan-IN-1 reduces lung metastasis of melanoma and prolongs the survival of mice. Hyaluronan-IN-1 can be used in research related to contact hypersensitivity, chronic skin inflammation, and melanoma[1][2][3]. Uses: Scientific research. Category: Peptides. CAS No. 299157-43-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5352. | |
| Hyaluronic acid | Hyaluronic acid is a biopolymer composed of repeating units of disaccharides with various applications. Hyaluronic acid is a major component of the extracellular matrix (ECM). Hyaluronic acid is synthesized at the plasma membrane. Increased hyaluronic acid levels are associated with tumor cell growth, adhesion, migration, invasion and angiogenesis in digestive cancers. Hyaluronic acid participates in tissue remodeling and rapid cell proliferation in some physiological processes including embryonic morphogenesis and wound-healing. Hyaluronic acid activates the PI3K-Akt signaling. Hyaluronic acid acts as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid also enhances cell invasion and angiogenesis by promoting proteolytic MMP-9 binding to cell surface or stimulating MMP-9 binding to cell surface. Hyaluronic acid can be used as drug delivery for sodium butyrate to improve the anti-proliferative activity on breast cancer cell line. Hyaluronic acid can be studied in joint diseases, wound healing and cancer[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hyaluronan; Hyaluronate. CAS No. 9004-61-9. Pack Sizes: 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-B0633A. | |
| Hyaluronic acid (Mw:1000-2000Da) | Hyaluronic acid (Mw: 1000-2000 Da) is a long-chain unbranched polysaccharide with a molecular weight of 1000-2000 Da. Hyaluronic acid (Mw: 2000 Da) inhibits IL-1β expression and increases LC3-II. Hyaluronic acid (Mw: 1000-2000Da) can regulate tissue homeostasis and stress resistance, promote angiogenesis and tissue remodeling. Hyaluronic acid (Mw: 1000-2000 Da) has good biocompatibility and biodegradability, and can be used in drug delivery systems and tissue engineering. Hyaluronic acid (Mw: 2000 Da) can reduce facial skin blemishes and sagging[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9004-61-9. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0633C. | |
| Hyaluronic acid (MW 50000-100000) | Hyaluronic acid (MW 50000-100000) (Hyaluronan (MW 50000-100000)) is a biopolymer composed of repeating units of disaccharides with a molecular weight of 50000-100000 Da. Hyaluronic acid (MW 50000-100000) can be used as a drug carrier for drug delivery[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hyaluronan (MW 50000-100000); Hyaluronate (MW 50000-100000). CAS No. 9004-61-9. Pack Sizes: 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-B0633B. | |
| Hyaluronic acid sodium | Hyaluronic acid sodium (Sodium hyaluronate) is a biopolymer composed of repeating units of disaccharides with various applications. Hyaluronic acid sodium is a major component of the extracellular matrix (ECM). Hyaluronic acid sodium is synthesized at the plasma membrane. Increased hyaluronic acid sodium levels are associated with tumor cell growth, adhesion, migration, invasion and angiogenesis in digestive cancers. Hyaluronic acid sodium participates in tissue remodeling and rapid cell proliferation in some physiological processes including embryonic morphogenesis and wound-healing. Hyaluronic acid sodium activates the PI3K-Akt signaling. Hyaluronic acid sodium acts as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid sodium also enhances cell invasion and angiogenesis by promoting proteolytic MMP-9 binding to cell surface or stimulating MMP-9 binding to cell surface. Hyaluronic acid sodium can be used as drug delivery for sodium butyrate to improve the anti-proliferative activity on breast cancer cell line. Hyaluronic acid sodium can be studied in joint diseases, wound healing and cancer[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sodium hyaluronate. CAS No. 9067-32-7. Pack Sizes: 50 mg; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-B0633. | |
| Hyaluronic acid sodium (MW 0.9M-1.0Mda) | Hyaluronic acid sodium (MW 0.9M-1.0Mda) (Sodium hyaluronate (MW 0.9M-1.0Mda)) is a biopolymer composed of repeating units of disaccharides with a molecular weight of 0.9 M-1.0 Mda. Hyaluronic acid sodium (MW 0.9M-1.0Mda) can be used as a drug carrier for drug delivery[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sodium hyaluronate (MW 0.9M-1.0Mda). CAS No. 9067-32-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-B0633P. | |
| Hyaluronic acid sodium (MW 200-1560) | Hyaluronic acid sodium (MW 200-1560) is a biopolymer composed of repeating disaccharide units, with a molecular weight of 200-1560. Hyaluronic acid sodium is a major component of the extracellular matrix (ECM). It is synthesized on the plasma membrane. Hyaluronic acid sodium exerts its effects by binding to receptors CD44 and RHAMM. Hyaluronic acid sodium activates PI3K-Akt signaling. Hyaluronic acid sodium also enhances cell invasion and angiogenesis by promoting or stimulating the binding of proteolytic MMP-9 to the cell surface. Elevated hyaluronic acid levels are associated with tumor cell growth, adhesion, migration, invasion, and angiogenesis in digestive system cancers. Hyaluronic acid sodium is involved in tissue remodeling and rapid cell proliferation in several physiological processes, including embryonic morphogenesis and wound healing. Hyaluronic acid sodium can be used as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid sodium can be used as a drug delivery carrier for sodium butyrate, enhancing its anti-proliferative activity against breast cancer cell lines. Hyaluronic acid sodium can lubricate the corneal endothelium. Hyaluronic acid sodium can improve tissue hydration and enhance the resistance of cells to mechanical damage. Hyaluronic acid sodium has been conjugated with antibodies to ensure that the active compound continues to exert its effects at the site of inf | |
| Hyaluronic acid sodium (MW 5000) | Hyaluronic acid (sodium) (MW 5000) is a biopolymer composed of repeating disaccharide units with a molecular weight of 5000. Hyaluronic acid (sodium) (MW 5000) can be used for dry-eye syndrome research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9067-32-7. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-B0633O. | |
| Hyaluronic acid sodium (MW 800kDa) | Hyaluronic acid sodium (MW 800kDa) is a biopolymer composed of repeating units of disaccharides with various applications. Hyaluronic acid sodium is a major component of the extracellular matrix (ECM). Hyaluronic acid sodium is synthesized at the plasma membrane. Increased hyaluronic acid sodium levels are associated with tumor cell growth, adhesion, migration, invasion and angiogenesis in digestive cancers. Hyaluronic acid sodium participates in tissue remodeling and rapid cell proliferation in some physiological processes including embryonic morphogenesis and wound-healing. Hyaluronic acid sodium activates the PI3K-Akt signaling. Hyaluronic acid sodium acts as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid sodium also enhances cell invasion and angiogenesis by promoting proteolytic MMP-9 binding to cell surface or stimulating MMP-9 binding to cell surface. Hyaluronic acid sodium can be used as drug delivery for sodium butyrate to improve the anti-proliferative activity on breast cancer cell line. Hyaluronic acid sodium can be studied in joint diseases, wound healing and cancer[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9067-32-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-B0633I. | |
| Hyaluronidase, Bovine testes | Hyaluronidase, Bovine testes (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is an endoglycosidase that depolymerizes Hyaluronic acid (HA) (HY-B0633A) by cleavage of glycosidic bonds. Hyaluronidase degrades HA and activates membrane receptors that trigger pathways converging in NF-κB activation. Hyaluronidase is employed in the research of granulomatous foreign body reactions, soft-tissue necrosis caused by vascular compromise and uncomplicated nodules, overcorrection, inflamed nodules or tissue ischemia associated with HA filler injection[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hyaluronate 4-glycanohydrolase, Bovine testes; Hyaluronoglucosaminidase, Bovine testes. CAS No. 37326-33-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107910. | |
| Hyaluronidase (human recombinant) | Hyaluronidase (human recombinant) (Vorhyaluronidase alfa; rHuPH 20) is an enzyme that catalyzes the degradation of hyaluronic acid. Hyaluronidase (human recombinant) is used to improve the absorption and dispersal of parenteral fluids, medications, and contrast media[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vorhyaluronidase alfa; rHuPH 20. CAS No. 37326-33-3. Pack Sizes: 150 U. Product ID: HY-108903. | |
| Hyaluronidase, Ovine testes | Hyaluronidase, Ovine testes is an endoglycosidase. Hyaluronidase, Ovine testes specifically degrades Hyaluronic acid (HY-B0633A) and Chondroitin sulfate (HY-B2162) by hydrolyzing β-glycosidic bonds in acidic mucopolysaccharides. Hyaluronidase, Ovine testes disperses follicular cells during fertilization by breaking down the hyaluronic acid-rich cumulus. Hyaluronidase, Ovine testes can be used in the study of fertility-related diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 37326-33-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108903A. | |
| Hycanthone | Hycanthone is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a KD of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3105-97-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1099. | |
| Hydralazine | Hydralazine is an orally active, blood-brain barrier-permeable DNA methyltransferase inhibitor with vasodilatory, arterial smooth muscle relaxant and hypotensive activities. Hydralazine reactivates silenced tumor suppressor genes via mediating DNA demethylation, while exerting neuroprotective and anti-inflammatory properties. Hydralazine inhibits NOS-2 (iNOS) and COX-2, and reduces the production of NO and PGEE2; meanwhile, Hydralazine scavenges reactive oxygen species and inhibits macrophage activation. Hydralazine alleviates motor dysfunction, neuropathic inflammatory pain, and formalin-induced somatic and emotional pain responses. In addition, Hydralazine directly induces DNA strand breaks and sister chromatid exchange, exhibiting certain mutagenic characteristics. Hydralazine has been widely used in studies on hypertension, various cancers (such as cervical cancer, leukemia), spinal cord injury and the mechanisms of inflammatory pain[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 86-54-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0464A. | |
| Hydralazine hydrochloride | Hydralazine hydrochloride is an orally active, blood-brain barrier-permeable DNA methyltransferase inhibitor with vasodilatory, arterial smooth muscle relaxant and hypotensive activities. Hydralazine hydrochloride reactivates silenced tumor suppressor genes via mediating DNA demethylation, while exerting neuroprotective and anti-inflammatory properties. Hydralazine hydrochloride inhibits NOS-2 (iNOS) and COX-2, and reduces the production of NO and PGEE2; meanwhile, Hydralazine hydrochloride scavenges reactive oxygen species and inhibits macrophage activation. Hydralazine hydrochloride alleviates motor dysfunction, neuropathic inflammatory pain, and formalin-induced somatic and emotional pain responses. In addition, Hydralazine hydrochloride directly induces DNA strand breaks and sister chromatid exchange, exhibiting certain mutagenic characteristics. Hydralazine hydrochloride has been widely used in studies on hypertension, various cancers (such as cervical cancer, leukemia), spinal cord injury and the mechanisms of inflammatory pain[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 304-20-1. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg. Product ID: HY-B0464. | |
| Hydrastine | Hydrastine ((-)-β-Hydrastine; (1R,9S)-β-Hydrastine) is a selective competitive inhibitor of tyrosine hydroxylase (TH), inhibiting dopamine biosynthesis (IC50=20.7 μM, PC12 cells). Hydrastine also inhibits the organic cation transporter OCT1 (IC50=6.6 μM). Hydrastine may cause neuronal toxicity through mitochondrial dysfunction rather than oxidative stress damage, and can aggravate cell apoptosis when combined with L-DOPA. Hydrastine can be used to study Parkinson's disease-related dopaminergic neuronal damage[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-β-Hydrastine; (1R,9S)-β-Hydrastine. CAS No. 118-08-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-B0927. | |
| Hydrastinine | Hydrastinine is a major alkaloid constituent in goldenseal (Hydrastis canadensis). Hydrastinine can be used as a haemostatic agent[1]. Uses: Scientific research. Category: Natural products. CAS No. 6592-85-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-B1181A. | |
| Hydrazine sulfate (99%) | Hydrazine sulfate is an orally active PEPCK inhibitor. Hydrazine sulfate inhibits PEPCK and low-Km ALDH. Hydrazine sulfate impairs gluconeogenesis and enhances the protective effect of energy substrates against MPP+ toxicity. Hydrazine sulfate exacerbates liver damage in rats when combined with Ethanol. Hydrazine sulfate can be used in the research of shock, non-small cell lung cancer, colorectal cancer and Parkinson's disease[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Diamine sulfate (99%). CAS No. 10034-93-2. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 100 g; 500 g; 1 k g; 5 k g. Product ID: HY-W115752. | |
| Hydrochlorothiazide | Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HCTZ. CAS No. 58-93-5. Pack Sizes: 500 mg; 5 g; 10 g. Product ID: HY-B0252. | |
| Hydrocortisone | Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex[1]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Cortisol. CAS No. 50-23-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-N0583. | |
| Hydrocortisone cypionate | Hydrocortisone cypionate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. Uses: Scientific research. Category: Signaling pathways. CAS No. 508-99-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg. Product ID: HY-U00089. | |
| Hydrocortisone-d4 | Hydrocortisone-d4 is the deuterium labeled Hydrocortisone. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cortisol-d4. CAS No. 73565-87-4. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-N0583S2. | |
| Hydrocortisone hemisuccinate | Hydrocortisone hemisuccinate (Hydrocortisone 21-hemisuccinate), a glucocorticoid, is an orally active steroidal anti-inflammatory agent (SAID) with anti-inflammatory and immunomodulatory activities. Hydrocortisone hemisuccinate inhibits the bioactivity of IL-6 and IL-3 with IC50 values of 6.7 and 21.4 μM, respectively. Hydrocortisone hemisuccinate can be used in the study of ulcerative colitis (UC) and recurrent oral ulcers[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hydrocortisone 21-hemisuccinate. CAS No. 2203-97-6. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-B1402. | |
| Hydrocortisone hemisuccinate sodium | Hydrocortisone hemisuccinate sodium is an orally active physiological glucocorticoid. Hydrocortisone hemisuccinate sodium inhibits proinflammatory cytokine activity, with IC50s of 6.7 and 21.4 μM for IL-6 and IL-3, respectively. Hydrocortisone hemisuccinate sodium can be used for the research of ulcerative colitis (UC)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hydrocortisone 21-hemisuccinate sodium. CAS No. 125-04-2. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1402B. | |
| Hydrocortisone (Standard) | Hydrocortisone (Standard) is the analytical standard of Hydrocortisone. This product is intended for research and analytical applications. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cortisol (Standard). CAS No. 50-23-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-N0583R. | |
| Hydrocotarnine | Hydrocotarnine is a Cbl inhibitor, and results in inflammasome-mediated IL-18 secretion in colitis. Hydrocotarnine increases expression of GLUT1 and cellular glucose uptake in glycolytic metabolism. Hydrocotarnine acts as an agent that provides analgesic effect in cancer research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 550-10-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W176629. | |
| Hydroflumethiazide | Hydroflumethiazide (Methforylthiazidine) is an orally active and potent thiazide diuretic. Hydroflumethiazide possesses the ability to directly stimulate A cell secretion in the normal and alloxan diabetic pancreas[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Methforylthiazidine; Rontyl. CAS No. 135-09-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-W011240. | |
| Hydrogenated soya phosphatidylcholine | Hydrogenated soya phosphatidylcholine (hydrogenated soybean phosphatidylcholine) is a natural product. Hydrogenated soya phosphatidylcholine can extend drug release in regard to drug loading and solubility for oral drug delivery of watersoluble drugs[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HSPC; Hydrogenated soybean phosphatidylcholine. CAS No. 97281-48-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-42990. | |
| Hydronidone | Hydronidone is an orally active pyridine derivative. Hydronidone is an inhibitor of phosphodiesterase-4 (PDE4) and cyclo-oxygenase (COX) as well as TGF-β. Hydronidone induces mitochondrial dysfunction and triggers apoptosis. Hydronidone can be used for liver fibrosis, anti-inflammation and anti-cancer study[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 851518-71-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100438. | |
| Hydroquinone diacetate | Hydroquinone diacetate (1,4-Diacetoxybenzene) is a diester product and also a commonly used synthetic intermediate for agrochemicals and fine chemicals. Hydroquinone diacetate can be produced via the acetylation of hydroquinone (HY-B0951) with acetic anhydride[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,4-Diacetoxybenzene. CAS No. 1205-91-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-118292. | |
| Hydroxocobalamin | Hydroxocobalamin (Vitamin B12a) is a cyanide antidote. Hydroxocobalamin can decrease the cell and plasma cyanide concentrations and increase survival rate in acute cyanide poisoning. Hydroxocobalamin can improve newborn Cbl-C defect-induced metabolic profile and neurocognitive outcome. Hydroxocobalamin can normalize Vitamin B12 deficiency. Hydroxocobalamin can induce acute kidney injury. Hydroxocobalamin can be used for the researches of metabolic and neurological disease[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitamin B12a. CAS No. 13422-51-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B2209. | |
| Hydroxocobalamin acetate | Hydroxocobalamin acetate is an injectable natural vitamin B12. Hydroxocobalamin acetate binds to NO. Hydroxocobalamin acetate detoxifies Cyanide and NaSH. Hydroxocobalamin acetate reduces hypotension. Hydroxocobalamin acetate is used in research related to vitamin B12 deficiency, including pernicious anemia[1][2][3][4][5][6][7][8]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitamin B12a acetate. CAS No. 22465-48-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B2209B. | |
| Hydroxy-α-sanshool | Hydroxy-α-sanshool is a transient receptor potential ankyrin 1 (TRPA1) and TRP vanilloid 1 (TRPV1) agonist with EC50s of 69 and 1.1 μM, respectively. Hydroxy-α-sanshool can be used for pain research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 83883-10-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N6825. | |
| Hydroxyamphetamine | Hydroxyamphetamine (4-Hydroxyamphetamine) is a sympathomimetic agent, stimulates the sympathetic nervous system. Hydroxyamphetamine can be used in eye drops to dilate the pupil[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Hydroxyamphetamine. CAS No. 103-86-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1098. | |
| Hydroxy-β-sanshool | Hydroxy-β-sanshool is an alkylamide exists in Zanthoxylum bungeanum oil and Zanthoxylum schinifolium oil[1]. Uses: Scientific research. Category: Natural products. CAS No. 97465-69-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6824. | |
| Hydroxybupropion | Hydroxybupropion is the major active metabolite of Bupropion. Hydroxybupropion is metabolized by CYP2B6. Bupropion is an atypical antidepressant and smoking-cessation agent. Hydroxybupropion inhibits norepinephrine uptake with an IC50 value of 1.7 μM. Hydroxybupropion is also a nACh receptor antagonist[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 92264-81-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-100637. | |
| Hydroxychlorodenafil | Hydroxychlorodenafil (compound 40) is a phosphodiesterase (PDE) inhibitor. Hydroxychlorodenafil can be used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1391054-00-4. Pack Sizes: 25 mg; 50 mg. Product ID: HY-135632. | |
| Hydroxychloroquine | Hydroxychloroquine (HCQ) is a synthetic oral antimalarial drug that can be used in the study of malaria and autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. Hydroxychloroquine is a potent autophagic flux inhibitor with antiviral activity (such as SARS-CoV-2 virus) that inhibits Toll-like receptor 7/9 (TLR7/9) signaling[1][2][3][4][5][6][7][8]. Uses: Scientific research. Category: Signaling pathways. CAS No. 118-42-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-W031727. | |
| Hydroxychloroquine (Standard) | Hydroxychloroquine (HCQ) is a synthetic oral antimalarial drug that can be used in the study of malaria and autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. Hydroxychloroquine is a potent autophagic flux inhibitor with antiviral activity (such as SARS-CoV-2 virus) that inhibits Toll-like receptor 7/9 (TLR7/9) signaling[1][2][3][4][5][6][7][8]. Uses: Scientific research. Category: Signaling pathways. CAS No. 118-42-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W031727R. | |
| Hydroxychloroquine sulfate | Hydroxychloroquine sulfate (HCQ sulfate) is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine sulfate is efficiently inhibits SARS-CoV-2 infection in vitro[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HCQ sulfate. CAS No. 747-36-4. Pack Sizes: 10 mM * 1 mL in Water; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B1370. | |
| Hydroxycitric acid | Hydroxycitric acid is an orally active, multi-target, multi-bioactive organic acid. activates Nrf2 and its downstream molecule GPX4, increases glutathione levels, and thereby inhibits ferroptosis. Hydroxycitric acid activates the Nrf2/Keap1 and ACLY/NF-κB signaling pathways, upregulates the activities of antioxidant enzymes such as superoxide dismutase, reduces MDA content, thereby alleviating oxidative stress and renal tubular epithelial cell apoptosis, and improves pulmonary vascular and right ventricular remodeling. Hydroxycitric acid activates both the AMPK and mTORC1/S6K pathways, triggers the unfolded protein response, arrests the cancer cell cycle, and induces DNA fragmentation[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6205-14-7. Pack Sizes: 50 mg; 100 mg. Product ID: HY-N1437. | |
| Hydroxycitric acid tripotassium | Tripotassium hydroxycitrate is an orally active, multi-target, multi-bioactive organic acid. Tripotassium hydroxycitrate activates Nrf2 and its downstream molecule GPX4, increases glutathione levels, and thereby inhibits ferroptosis. Tripotassium hydroxycitrate activates the Nrf2/Keap1 and ACLY/NF-κB signaling pathways, upregulates the activities of antioxidant enzymes such as superoxide dismutase, reduces MDA content, thereby alleviating oxidative stress and renal tubular epithelial cell apoptosis, and improves pulmonary vascular and right ventricular remodeling. Tripotassium hydroxycitrate activates both the AMPK and mTORC1/S6K pathways, triggers the unfolded protein response, arrests the cancer cell cycle, and induces DNA fragmentation[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 232281-44-6. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg. Product ID: HY-W338584. | |
| Hydroxy-Dynasore | Hydroxy Dynasore (Dyngo-4a), a structural mimetic analog of Dynasore (HY-15304), is an improved, less cytotoxic and versatile dynamin inhibitor with IC50 values ??of 0.38 μM and 2.3 μM for brain recombinant dynamin I and recombinant mouse dynamin II, respectively. Hydroxy Dynasore inhibits dynamin-dependent transferrin endocytosis with an IC50 of 5.7 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dyngo-4a. CAS No. 1256493-34-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13863. | |
| Hydroxyethyl starch (Mw 110-150 kDa) | Hydroxyethyl starch (Mw 110-150 kDa) is a biochemical reagent used in drug delivery and other research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9005-27-0. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-W145519A. | |
| Hydroxyethyl starch (MW170-230 kDa) | Hydroxyethyl starch (MW170-230 kDa) is a type of hydroxyethyl starch with a molecular weight of 170-230 kDa. A medium-molecular-weight hydroxyethyl starch (HES 200/0.62) exhibits minimal intravascular hydrolysis. The rapidly degradable medium-molecular-weight Hydroxyethyl starch 200/0.5 causes almost no coagulation disorders and improves hemorheological parameters[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9005-27-0. Pack Sizes: 25 g; 50 g; 100 g; 500 g; 1 k g. Product ID: HY-W145519. | |
| Hydroxyfasudil | Hydroxyfasudil is a ROCK inhibitor, with IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HA-1100. CAS No. 105628-72-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13911. | |
| Hydroxyflutamide | Hydroxyflutamide (HFT) is the active metabolite of Flutamide (HY-B0022) and exhibits oral activity. Hydroxyflutamide is a potent androgen receptor antagonist with an IC50 of 700 nM. Hydroxyflutamide can affect embryonic development and reproductive tract development in mice. Additionally, Hydroxyflutamide can enhance the efficacy of Bacillus Calmette-Guérin (BCG) to better inhibit the progression of bladder cancer. Hydroxyflutamide can be used in research related to tumors and reproductive diseases[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HFT. CAS No. 52806-53-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W013272. | |
| Hydroxyisohexyl 3-cyclohexene carboxaldehyde | Hydroxyisohexyl 3-cyclohexene carboxaldehyde is a hapten probe[1]. Uses: Scientific research. Category: Induced disease models products. CAS No. 31906-04-4. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg. Product ID: HY-W035214. | |
| Hydroxy Itraconazole | Hydroxy Itraconazole (R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R-63373. CAS No. 112559-91-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12772. | |
| Hydroxylamine hydrochloride | Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms, such as ammonium oxidizing bacteria (AOB), ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox). Hydroxylamine hydrochloride impacts NO and N2O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5470-11-1. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-Y0882. | |
| Hydroxylapatite (<50 nm) | Hydroxylapatite (Hydroxyapatite) (<50 nm) is a natural form of calcium phosphate and is the main mineral component of bones and teeth. Hydroxylapatite (<50 nm) can stimulate the expression and secretion of collagen in primary human dermal fibroblasts. Hydroxylapatite (<50 nm) has good biocompatibility, bioactivity, and bone conductivity, making it suitable for targeted drug or nucleic acid delivery. Hydroxylapatite (<50 nm) can be used in research on osteoarthritis, gout, and atherosclerosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hydroxyapatite (<50 nm). CAS No. 1306-06-5. Pack Sizes: 500 mg; 1 g. Product ID: HY-D0835A. | |
| Hydroxynaphthol Blue | Hydroxynaphthol Blue is an azo dye and serves as a metal indicator. Hydroxynaphthol Blue binds to specific metal ions to form stable complexes with distinct color and fluorescence properties. Hydroxynaphthol Blue is used for the visual monitoring of isothermal nucleic acid amplification results. A visible color difference appears between positive and negative nucleic acid amplification reactions, allowing result discrimination by the naked eye without opening the reaction tube[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 63451-35-4. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 250 mg; 1 g. Product ID: HY-D1247. | |
| Hydroxy-PEG2-acid | Hydroxy-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1334286-77-9. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-124380. | |
| Hydroxy-PEG4-(CH2)2-Boc | Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 191). Hydroxy-PEG4-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 518044-32-1. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 100 g. Product ID: HY-W039178. | |
| Hydroxyphenyl Fluorescein | Hydroxyphenyl Fluorescein (HPF) is a stable ROS fluorescent probe dye. Hydroxyphenyl Fluorescein has stronger specificity and stability than H2DCFDA (HY-D0940). Hydroxyphenyl Fluorescein can produce strong green fluorescence through hydroxyl radical reaction with intracellular peroxynitroso. Hydroxyphenyl Fluorescein can be applied for fluorescence microscopy, high-throughput imager, luciferase microplate reader or flow cytometry. Ex/Em=490/515 nm[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HPF; 3'-p-(Hydroxyphenyl) fluorescein. CAS No. 359010-69-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111330. | |
| Hydroxyphenyl Fluorescein (solution) | Hydroxyphenyl Fluorescein (HPF) (solution) is a stable ROS fluorescent probe dye. Hydroxyphenyl Fluorescein has stronger specificity and stability than H2DCFDA (HY-D0940). Hydroxyphenyl Fluorescein can produce strong green fluorescence through hydroxyl radical reaction with intracellular peroxynitroso. Hydroxyphenyl Fluorescein can be applied for fluorescence microscopy, high-throughput imager, luciferase microplate reader or flow cytometry. Ex/Em=490/515 nm[1].Solvent and concentration: DMSO: 10 mM. Uses: Scientific research. Category: Signaling pathways. CAS No. 359010-69-8. Pack Sizes: 50 μL; 100 μL. Product ID: HY-DY1035. | |
| Hydroxyphenyllactic acid | Hydroxyphenyllactic acid is an antifungal metabolite. Uses: Scientific research. Category: Signaling pathways. CAS No. 306-23-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113219. | |
| Hydroxyphenyllactic acid (Standard) | Hydroxyphenyllactic acid (Standard) is the analytical standard of Hydroxyphenyllactic acid. This product is intended for research and analytical applications. Hydroxyphenyllactic acid is an antifungal metabolite. Uses: Scientific research. Category: Signaling pathways. CAS No. 306-23-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-113219R. | |
| Hydroxypinacolone retinoate | Hydroxypinacolone retinoate (HPR) is a retinol derivative, which binds directly with retinoic acid receptors (RARs). Hydroxypinacolone retinoate, when used in combination with Retinyl propionate, can be used in anti-skin aging research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HPR. CAS No. 893412-73-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-W442049. | |
| Hydroxy-PP-Me | Hydroxy-PP-Me is a selective CBR1 inhibitor with an IC50 of 759 nM. Hydroxy-PP-Me can inhibit serum starvation-induced apoptosis. Hydroxy-PP-Me can enhance the cytotoxic effects of Daunorubicin (HY-13062A) and As2O3 on tumor cells. Hydroxy-PP-Me can be used in the research of cancer such as leukemia[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 833481-77-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156694. | |
| Hydroxyproline | Hydroxyproline (DL-Hydroxyproline) is a non-essential amino acid and one of the main components of collagen tissue. Hydroxyproline can be used in research on endocrine and metabolic diseases, as well as genetic diseases and malformations. Hydroxyproline can also serve as a biomarker[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DL-Hydroxyproline. CAS No. 6912-67-0. Pack Sizes: 10 mM * 1 mL in Water; 250 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W343900. | |
| Hydroxypropylmethyl cellulose acetate succinate (Mw:20-100 kDa) | Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) is a cosolvent for preparing SDDs of low-solubility agents. Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) exhibits no acute/subchronic/chronic toxicity in rats, with oral activity and LD50 >2.5 g/kg[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 71138-97-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152927. | |
| Hydroxypyruvic acid phosphate lithium | Hydroxypyruvic acid phosphate lithium serves as a crucial metabolic intermediate in the biosynthesis of L-Serine (HY-N0650), being formed from the conversion of the glycolytic intermediate 3-phosphoglycerate through the action of 3-phosphoglycerate dehydrogenase. Uses: Scientific research. Category: Signaling pathways. CAS No. 2080296-02-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W552257A. | |
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