MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Insulin aspart | Insulin aspart (B28Asp) is a rapid-acting h-Insulin (HY-P0035) analog. Insulin aspart induces a faster hypoglycemic effect. Insulin aspart can be used in diabetes-related research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: B28Asp; B28-Asp-insulin; INA-X 14; Insulin X 14. CAS No. 116094-23-6. Pack Sizes: 100 U; 300 U. Product ID: HY-108767. |  |
| Insulin β Chain Peptide (15-23) | Insulin β Chain Peptide (15-23) is one of the earliest antigenic epitopes to which CD8 T-cells respond[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 247044-67-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2511. | |
| Insulin(cattle) | Insulin cattle is a two-chain polypeptide hormone produced in vivo in the pancreatic β cells. Insulin cattle has often been used as growth supplement in culturing cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 11070-73-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1156. | |
| Insulin degludec | Insulin degludec is an ultra-long-acting form of insulin used for the research of hyperglycemia caused by type 1 and type 2 dabetes. Insulin degludec shows binding efficiency with an IC50 value of 19.59 nM for insulin receptor. Insulin degludec can be used for the research of type 1 and type 2 diabetes[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 844439-96-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108743. | |
| Insulin Detemir | Insulin Detemir is an artificial insulin, shows effect on controlling blood sugar levels. Insulin Detemir stimulates GLP-1 secretion as a consequence of enhanced Gcg expression by a mechanism involving activation of Akt- and/or extracellular signal-regulated kinase (ERK)-dependent-cat and CREB signaling pathways. Insulin Detemir can be used for type 2 diabetes research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 169148-63-4. Pack Sizes: 100 U; 300 U. Product ID: HY-109556. | |
| Insulin efsitora alfa | Insulin efsitora alfa (LY-3209590) is a selective agonist of insulin receptor (IR). Insulin efsitora alfa is a fusion protein composed of human IR agonists fused with the crystallizable (Fc) domain of human immunoglobulin G2 (IgG2) fragment, with a molecular weight of 64.1 kDa. Insulin efsitora alfa is well tolerated and has potential applications in diabetes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY-3209590. CAS No. 2131038-11-2. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P99665. | |
| Insulin glargine | Insulin glargine is a long-acting insulin analog. Insulin glargine has the effect of lowering blood sugar and can be used in the research of diabetes. In addition, high doses of Insulin glargine can promote the proliferation of bladder cancer cells[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 160337-95-1. Pack Sizes: 100 U; 300 U. Product ID: HY-108719. | |
| Insulin glulisine | Insulin glulisine (HMR 1964) is a rapid-acting insulin analog whose pharmacokinetic and pharmacodynamic properties mimic physiological insulin secretion in humans, with a rapid onset of action. Insulin glulisine controls hyperglycemia. Insulin glulisine is applicable to research related to type 1 diabetes and type 2 diabetes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HMR 1964. CAS No. 207748-29-6. Pack Sizes: 100 U. Product ID: HY-109555. | |
| Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of glucose. Insulin (human) can be used for the diabetes mellitus[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 11061-68-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-P0035. | |
| Insulin icodec | Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1188379-43-2. Pack Sizes: 1 mL. Product ID: HY-P4070. | |
| Insulin solution (human) | Insulin solution (human) is a polypeptide hormone that regulates the level of glucose. Insulin solution (human) can be used for the diabetes mellitus[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 11061-68-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0035A. | |
| Insulin (swine) | Insulin (swine) is an orally active insulin derived from pigs. Insulin (swine) when administered orally acts as an antigen to reduce the severity of pancreatic lymphocyte infiltration, but has no metabolic effect on blood glucose levels. Insulin (swine) increases glucose oxidation, stimulates lipogenesis, and lowers blood glucose levels. Insulin (swine) can be used in diabetes research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 12584-58-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3479. | |
| INT | INT (Iodonitrotetrazolium chloride) is a biochemical reagent mainly used in the iodonitrotetrazolium chloride (INT) colorimetric method to assess the metabolic activity of cells and the activity of enzymes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Iodonitrotetrazolium chloride; p-Iodonitrotetrazolium Violet. CAS No. 146-68-9. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-15920. | |
| INT-767 | INT-767 is a dual farnesoid X receptor (FXR)/TGR5 agonist with mean EC50s of 30 and 630 nM, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1000403-03-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12434. | |
| INT-777 | INT-777 is a potent TGR5 agonist with an EC50 of 0.82 μM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S-EMCA. CAS No. 1199796-29-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15677. | |
| Integrin antagonist 27 | Integrin antagonist 27 (Compound 27) is a small molecule integrin αvβ3 antagonist with an affinity of 18 nM. Integrin antagonist 27 can be combined with Paclitaxel (HY-B0015) to selectively target αvβ3-positive metastatic cancer cells. Integrin antagonist 27 is used as an anticancer agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 593274-97-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18668. | |
| Intepirdine | Intepirdine (SB742457) is a highly selective 5-HT6 receptor antagonist with pKi of 9.63; exhibits >100-fold selectivity over other receptors. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SB-742457; GSK-742457; RVT-101. CAS No. 607742-69-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14339. | |
| Intermedin (human) | Intermedin (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1]. Uses: Scientific research. Category: Peptides. CAS No. 1188922-20-4. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P4723. | |
| Intetumumab | Intetumumab (CNTO 95) is a human monoclonal antibody targeting αv integrin, with a Kd value of 1-24 nM. Through high-affinity binding to αv integrin, Intetumumab inhibits its interaction with extracellular matrix proteins (such as vitronectin and fibronectin), thereby blocking the downstream focal adhesion kinase signaling pathway. This further inhibits the adhesion, migration and invasion of tumor cells as well as the proliferation of vascular endothelial cells, promotes cell apoptosis, and exerts anti-tumor and anti-angiogenic effects. Intetumumab can be used in research related to head and neck cancer, non-small cell lung cancer and uterine serous papillary carcinoma[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CNTO 95; Anti-Human CD51 Recombinant Antibody. CAS No. 725735-28-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99296. | |
| Intralipid 20% | Intralipid 20% is a safe fat emulsion that can be used as a nutritional supplement. Intralipid 20% effectively inhibits the opening of the mitochondrial permeability transition pore, effectively protecting the heart from ischaemia-reperfusion injury and has some potential to modulate the innate immune response[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 68890-65-3. Pack Sizes: 1 mL; 5 mL; 10 mL; 50 mL; 100 mL. Product ID: HY-131370B. | |
| Inulin | Inulin is an orally active prebiotic targeting the intestinal microbiota, selectively promoting the proliferation and activity of beneficial bacteria such as bifidobacteria and lactic acid bacteria, and playing a role in regulating the intestinal microecology. The functions of Inulin include: Fermentation by probiotics in the colon to produce short-chain fatty acids (such as butyrate and propionate), lowering the intestinal pH and inhibiting the overgrowth of harmful bacteria; Enhancing the intestinal barrier function and reducing endotoxin translocation; Directly scavenging free radicals (such as superoxide free radicals, hydroxyl free radicals) and activating antioxidant enzymes (SOD, CAT) to reduce oxidative stress. Inulin can also be used in the study of intestinal diseases (constipation, IBD), metabolic syndrome (diabetes, obesity) and liver damage by regulating glucose and lipid metabolism (such as reducing triglycerides, improving insulin sensitivity) and immune response (enhancing NK cell activity, inhibiting inflammatory factors) | |
| Inulinase | Inulinase is expressed in various microorganisms, including yeasts, fungi, mesophilic bacteria. Inulinase can be used to produce inulooligosaccharides from inulin and inulin-containing materials. Inulinase produced by yeast has hydrolysing capability towards sucrose, inulin, levan type fructans exo-wise[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9025-67-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-P3261. | |
| Inupadenant | Inupadenant is an orally active, highly selective A2A receptor antagonist. Inupadenant can not cross BBB. Inupadenant can enhance the humoral immune response and has anti-tumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EOS-850. CAS No. 2246607-08-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137442. | |
| Invertase, baker's yeast (S. cerevisiae) | Invertase, baker's yeast (S. cerevisiae) is a major enzyme present in plants and microorganisms, is often used in biochemical studies. Invertase catalyzes the hydrolysis of the disaccharide sucrose into glucose and fructose[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: β-D-Fructofuranosidase. CAS No. 9001-57-4. Pack Sizes: 250 mg; 500 mg; 1 g. Product ID: HY-P2979. | |
| INX-315 | INX-315 is an orally active and selective CDK2 inhibitor that induces cell cycle arrest in the G1 phase. INX-315 reduces CDK2 substrate phosphorylation and inhibits tumor growth in a dose-dependent manner in xenograft mouse models. INX-315 may be used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2745060-92-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-162001. | |
| INY-03-041 | INY-03-041 is a potent, highly selective and PROTAC-based pan-AKT degrader consisting of the ATP-competitive AKT inhibitor Ipatasertib (HY-15186) conjugated to Lenalidomide (HY-A0003, Cereblon ligand). INY-03-041 inhibits AKT1, AKT2 and AKT3 with IC50s of 2.0, 6.8 and 3.5 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2503017-97-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-133120. | |
| INY-05-040 | INY-05-040 is an AKT degrader that can selectively and quickly degrade all three AKT isoforms. INY-05-040 exhibits anti-cancer activity. INY-05-040 can inhibit downstream signaling and cell proliferation in 288 cancer cell lines. INY-05-040 can suppress AKT signaling and induces the stress mitogen-activated protein kinase (MAPK) c-Jun N-terminal kinase (JNK). INY-05-040 is effective for breast cancer lines with a low-baseline activation of stress MAPK pathway. INY-05-040 can be studied for anti-cancer research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2503018-29-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-160469. | |
| Inz-5 | Inz-5 is a fungal-selective mitochondrial cytochrome bc1 inhibitor. Inz-5 impairs fungal virulence and prevents the evolution of agent resistance[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1585214-21-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121721. | |
| Iodipamide | Iodipamide (Adipiodone) is an ionic iodinated contrast agent. Iodipamide is used for diagnostic imaging to visualize the bile ducts and gallbladder during X-ray examinations[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adipiodone. CAS No. 606-17-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1292. | |
| Iodixanol | Iodixanol is an iodine-containing non-ionic radiocontrast agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 92339-11-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-B1426. | |
| Iodoacetamide-PEG3-azide | Iodoacetamide-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Iodoacetamide-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1594986-04-5. Pack Sizes: 100 mg; 250 mg. Product ID: HY-140857. | |
| Iodocholine iodide | Iodocholine iodide is a non-toxic, metabolizable "green" catalyst that can catalyze the free radical polymerization of functional polymers. Iodocholine iodide is also the non-radioactive iodide of Carbon-11 choline. C-11 Choline can be used in PET imaging and non-informative bone scintigraphy, CT or MRI to monitor various types of cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 28508-22-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-W130177. | |
| Iohexol | Iohexol is a non-ionic, water-soluble contrast agent used as a reference marker for the determination of glomerular filtration rate (GFR) at the level of renal function. Iohexol can be used for contrast in myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 66108-95-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B0594. | |
| Iohexol-d5 | Iohexol-d5 is deuterium labeled Iohexol. Iohexol is a radiographic contrast agent and can be applied for myelography, computerized tomography?(cisternography, ventriculography) and MicroCT imaging in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 928623-33-0. Pack Sizes: 1 mg. Product ID: HY-B0594S. | |
| Iomeprol | Iomeprol is a nonionic X-ray contrast agent with low osmotic pressure, stable chemical properties, and can withstand high temperature sterilization. Iomeprol can be widely used in vascular, body cavity, and gastrointestinal angiography examinations[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 78649-41-9. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-150137. | |
| Ionizable lipid-1 | Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2055939-68-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156630. | |
| Ionomycin | Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SQ23377. CAS No. 56092-81-0. Pack Sizes: 1 mg (14.1 mM * 100 μL in Ethanol); 5 mg (14.1 mM * 500 μL in Ethanol); 10 mg (14.1 mM * 1 mL in Ethanol); 25 mg (14.1 mM * 2.5 mL in Ethanol); 50 mg (14.1 mM * 5 mL in Ethanol). Product ID: HY-13434. | |
| Ionomycin calcium | Ionomycin calcium (SQ23377 calcium) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin calcium (SQ23377 calcium) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin calcium (SQ23377 calcium) also induces the activation of protein kinase C (PKC)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SQ23377 calcium. CAS No. 56092-82-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13434A. | |
| Ionox 330 | Ionox 330 (Tris-BHT Mesitylene) is a phenolic antioxidant in a variety of chemical and biological products. Ionox 330 can be used primarily as an antioxidant for polyalkenes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tris-BHT Mesitylene. CAS No. 1709-70-2. Pack Sizes: 25 g; 100 g; 500 g. Product ID: HY-120388. | |
| Iopamidol | Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: B-15000; SQ-13396. CAS No. 60166-93-0. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0684. | |
| Iopromide | Iopromide is a non-ionic, monomeric, iodine-based contrast medium for intravascular administration. Uses: Scientific research. Category: Signaling pathways. CAS No. 73334-07-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-B1362. | |
| Iotalamic acid | Lotalamic acid (Iothalamic acid) is a contrast agent. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Iothalamic acid. CAS No. 2276-90-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1053. | |
| Ioversol | Ioversol (MP-328) is a nonionic iodinated contrast medium (CM) that is used during a CT scan or x-ray in animal experiment. Ioversol does not damage the blood-brain barrier (BBB) in animal[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MP-328. CAS No. 87771-40-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1410. | |
| IOX1 | IOX1, a chemical probe, is a potent broad?spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases. IOX1 inhibits KDM4C, KDM4E, KDM2A, KDM3A and KDM6B with IC50 values of 0.6 μM, 2.3 μM, 1.8 μM, 0.1 μM and 1.4 μM, respectively[1][2]. IOX1 also inhibits ALKBH5[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5852-78-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-12304. | |
| IOX2 | IOX2, a chemical probe, is a specific prolyl hydroxylase-2 (PHD2) inhibitor with IC50 of 22 nM. IOX2 regulates platelet function and arterial thrombosis by upregulating HIF-1α expression and inhibiting ROS production. IOX2 can be used in the study of thrombotic diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 931398-72-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15468. | |
| IOX4 | IOX4 is a selective HIF prolyl-hydroxylase 2 (PHD2) inhibitor with an IC50 value of 1.6 nM, induces HIFα in cells and in wildtype mice with marked induction in the brain tissue. IOX4 competes with and displaces 2-oxoglutarate (2OG) at the active site of PHD2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1154097-71-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120110. | |
| IP3RPEP6 | IP3RPEP6 is an IP3R competitive inhibitor. IP3RPEP6 has the IC50 values of 9.0 μM, 3.9 μM and 4.3 μM for IP3R1, IP3R2 and IP3R3, respectively. IP3RPEP6 does not affect the Ryanodine receptor and Cx43 hemichannels. IP3RPEP6 regulates calcium signaling within cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3061802-23-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P10849. | |
| IP7e | IP7e is a potent, brain-penetrant and orally active Nurr1 activator with an EC50 value of 3.9 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 500164-74-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110274. | |
| IPA-3 | IPA-3 is a selective non-ATP competitive PAK1 inhibitor with IC50 of 2.5 μM, and shows no inhibition to group II PAKs (PAKs 4-6). Uses: Scientific research. Category: Signaling pathways. CAS No. 42521-82-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15663. | |
| iPAF1C | iPAF1C is a inhibitor of the polymerase-associated factor 1 complex (PAF1C) with specific targeting to the PAF1 binding groove of CTR9 (a key subunit of PAF1C). iPAF1C disrupts PAF1C assembly by interfering with the PAF1-CTR9 interaction. iPAF1C selectively impairs BRD4-mediated recruitment of PAF1 to chromatin at hypoxia-responsive genes and inhibits RNA polymerase II (RNAPII) pause release. iPAF1C increases the population of HIV-1 NL4.3 Nef-IRES-GFP infected primary human CD4+T cells in a dose-dependent manner. PAF1C can be used for the study of infection and diseases associated with abnormal hypoxic adaptation (e.g., cancers, neurological disorders)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 950403-60-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160267. | |
| Ipafricept | Ipafricept (OMP-54F28; FZD8-Fc) is a first class recombinant fusion protein with the extracellular part of the human frizzled-8 receptor fused to a human IgG1 Fc fragment that binds Wnt ligands, which blocks Wnt signaling. Ipafricept reduces tumor growth and results in a decrease in both liver and lung metastases combined with Gemcitabine (HY-17026) in pancreatic cancer mouse models. Ipafricept shows solid tumor inhibition activity with well tolerance, such as desmoid tumor, germ cell cancer, ovarian cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OMP-54F28; FZD8-Fc. CAS No. 1391727-24-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99667. | |
| Ipatasertib | Ipatasertib (GDC-0068) is an orally active, highly selective and ATP-competitive pan-Akt inhibitor with IC50 values of 5, 18, 8 nM for Akt1/2/3, respectively. Ipatasertib synchronously activates FoxO3a and NF-κB through inhibition of Akt leading to p53-independent activation of PUMA. Ipatasertib also induces apoptosis in cancer cells and inhibits tumor growth in xenograft mouse models[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GDC-0068; RG7440. CAS No. 1001264-89-6. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15186. | |
| Ipatasertib dihydrochloride | Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive pan-Akt inhibitor with IC50s of 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GDC-0068 dihydrochloride; RG-7440 dihydrochloride. CAS No. 1396257-94-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15186A. | |
| Iperoxo | Iperoxo is a potent superagonist of muscarinic acetylcholine receptor (mAChR) that activates M1, M2 and M3 receptors with pEC50 of 9.87, 10.1 and 9.78. Iperoxo can be used for direct probing activation-related conformational transitions of muscarinic receptors when labeled with tritium[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 247079-84-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-122743. | |
| Ipflufenoquin | Ipflufenoquin is an insecticide with the potential to control primary infection with apple scab. Ipflufenoquin should be applied between half an inch of green and fruit set[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1314008-27-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134338. | |
| IPI-9119 | IPI-9119 is an orally active, selective and irreversible FASN inhibitor with an IC50 of 0.3 nM in vitro biochemical assay. IPI-9119 inhibits tumor growth of castration-resistant prostate cancer (CRPC) xenografts mouse models[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1346564-56-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124628. | |
| Ipilimumab | Ipilimumab is a fully human monoclonal antibody IgG1κ that blocks the inhibitory receptor cytotoxic T lymphocyte antigen 4 (CTLA-4) on T cells. Ipilimumab can be used in unresectable or metastatic melanoma (MM) studies[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MDX-010; BMS-734016. CAS No. 477202-00-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P9901. | |
| Ipivivint | Ipivivint (Compound 38) is an orally active and potent CDC-like kinase (CLK) inhibitor with EC50 of 1 nM and 7 nM for CLK2 (human) and CLK3 (human), respectively. Ipivivint also inhibits the Wnt pathway (EC50=13 nM) and tyrosine phosphorylation-regulated kinase 1A (human) (EC50=5 nM)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1481617-15-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137443. | |
| IPN60090 | IPN-60090 is an orally active and highly selective inhibitor of glutaminase 1 (GLS1; IC50=31 nM), with no activity observed against GLS-2. IPN-60090 exhibits excellent physicochemical and pharmacokinetic properties in vivo. IPN-60090 can be used for solid tumors research, such as lung and ovarian cancers[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1853164-83-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103671. | |
| IPR-803 | IPR-803 is a potent inhibitor of the uPAR·uPA protein-protein interaction (PPI). IPR-803 binds directly to uPAR with sub-micromolar affinity. IPR-803 displays anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 892243-35-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111192. | |
| Ipragliflozin | Ipragliflozin (ASP1941) is an orally active and selective SGLT2 inhibitor with IC50s of 7.38 and 1876 nM, 6.73 and 1166 nM, 5.64 and 1380 nM for human SGLT2 and SGLT1, rat SGLT2 and SGLT1, mouse SGLT2 and SGLT1, respectively. Antidiabetic agent[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASP1941. CAS No. 761423-87-4. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-14894. | |
| Ipriflavone | Ipriflavone is a synthetic isoflavone derivative used to suppress bone resorption. Uses: Scientific research. Category: Signaling pathways. CAS No. 35212-22-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-N0094. | |
| Iprodione (Standard) | Iprodione (Standard) is the analytical standard of Iprodione. This product is intended for research and analytical applications. Iprodione is an orally active diformimide fungicide. Iprodione can specifically cause oxidative damage by producing free radicals (ROS). Iprodione is also an antiandrogen agent that delays adolescent development in rats and reduces sexual behavior and reproductive ability in rats[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 36734-19-7. Pack Sizes: 10 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B1978R. | |
| Ipsapirone | Ipsapirone (TVX Q 7821) is an anxiolytic compound and a 5-HT1A receptor partial agonist. Ipsapirone (TVX Q 7821) also exhibits 5-HT1A receptor antagonistic effect, and only at high doses it can also produce an inhibitory effect on 5-HT2 and the α1-adrenergic function[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TVX Q 7821 free base. CAS No. 95847-70-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19686. | |
| (±)-Ipsdienol | (±)-Ipsdienol is a sex pheromone with an inducing effect on male spruce beetles (Dendroctonus rufipennis Kirby), which can be isolated from the subspecies of spruce beetles (Ips tridens Mannerheim)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 14434-41-4. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg. Product ID: HY-W613915. | |
| Iptacopan | Iptacopan (LNP023) is an effective and orally-active highly selective factor B inhibitor with an IC50 value of 10 nM and KD of 7.9 nM. Iptacopan exerts a proximal effect in the complement cascade reaction, preventing the destruction (hemolysis) of red blood cells in PNH and the damage of renal cells in IgAN and C3G. Iptacopan can be used for the study of complement-mediated diseases, particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LNP023. CAS No. 1644670-37-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-127105. | |
| Iptacopan hydrochloride | Iptacopan (LNP023) hydrochloride is an effective and orally-active highly selective factor B inhibitor with an IC50 value of 10 nM and KD of 7.9 nM. Iptacopan hydrochloride exerts a proximal effect in the complement cascade reaction, preventing the destruction (hemolysis) of red blood cells in PNH and the damage of renal cells in IgAN and C3G. Iptacopan hydrochloride can be used for the study of complement-mediated diseases, particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LNP023 hydrochloride. CAS No. 1646321-63-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-127105A. | |
| IPTG | IPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon, and it is therefore used to induce protein expression where the gene is under the control of the lac operator. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Isopropyl β-D-thiogalactoside. CAS No. 367-93-1. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-15921. | |
| Iptriazopyrid | Iptriazopyrid (NC-656) is an azole carboxamide herbicide targeting 4-hydroxyphenylpyruvate dioxygenase (HPPD) with a Ki value of 24.3 nM for Arabidopsis HPPD and 33.3 nM for rice HPPD. Iptriazopyrid blocks plastoquinone and carotenoid synthesis, leading to weed chlorosis and death. Iptriazopyrid is promising for research of controlling weeds such as Echinochloa crus-galli in paddy fields[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NC-656. CAS No. 1994348-72-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-174423. | |
| IR-1048 | IR-1048 is a nitroreductase (NTR)-responsive near-infrared fluorescence (NIR)/photoacoustic (PA) imaging probe and photothermal agent. IR-1048 is coupled with a nitroimidazole group to form IR-1048-MZ. IR-1048-MZ is catalytically reduced by NTR in a hypoxic environment, restoring strong near-infrared absorption and fluorescence emission (NIR II window), while activating the photothermal effect. IR-1048 relies on NTR-mediated electron transfer to relieve intramolecular fluorescence quenching, achieving specific imaging and photothermal ablation of tumor hypoxic areas. IR-1048 is mainly used for high-contrast NIR II/photoacoustic imaging and photothermal therapy research and tumor diagnosis of the tumor hypoxic microenvironment[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S01448. CAS No. 155613-98-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-D1450. | |
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