MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Isocyclosporin A | Isocyclosporin A is a degradation product of the immunosuppressant Cyclosporin A[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 59865-16-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129072. |  |
| Isodeoxycholic acid | Isodeoxycholic acid (7α,12α-Dihydroxycholanoic acid) is a 3β-hydroxylated secondary bile acid. Isodeoxycholic acid is produced by epimerization of deoxycholic acid by intestinal bacteria. Isodeoxycholic acid is detectable in feces, mainly existing as saponifiable conjugates with long-chain fatty acids. Isodeoxycholic acid participates in the regulation of intestinal physiology[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 7α,12α-Dihydroxycholanoic acid. CAS No. 566-17-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-W399297. | |
| Isodeoxyelephantopin | Isodeoxyelephantopin is a sesquiterpene lactone isolated from Elephantopus scaber. Isodeoxyelephantopin induces ROS generation, suppresses NF-κB activation. Isodeoxyelephantopin also modulates LncRNA expression and exhibit activities against breast cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 38927-54-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2585. | |
| Isodiospyrin | Isodiospyrin, a natural dimeric naphthoquinone, is a human DNA topoisomerase I (Topoisomerase) inhibitor. Isodiospyrin can prevent both DNA relaxation and kinase activities of human topoisomerase I. Isodiospyrin shows anticancer, antibacterial and antifungal activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 20175-84-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N3488. | |
| Isoescin IA | Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. Isoescin IA has anti-HIV-1 protease activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 219944-39-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0556. | |
| Isoescin IB | Isoescin IB is an isomer of Escin IB. Isoescin IB and Escin IB are the chief active ingredients in escin[1]. Uses: Scientific research. Category: Natural products. CAS No. 219944-46-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0557. | |
| Isoferulic acid (Standard) | Isoferulic acid (Standard) (3-Hydroxy-4-methoxycinnamic acid (Standard)) is the analytical standard of Isoferulic acid (HY-N0761). This product is intended for research and analytical applications. Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is an orally active cinnamic acid derivative. Isoferulic acid exhibits hypoglycemic, antiviral, and antioxidant activities. Isoferulic acid can also inhibit fructose- and glucose-mediated protein glycation. Isoferulic acid can be used in the research of diseases such as diabetes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3-Hydroxy-4-methoxycinnamic acid (Standard). CAS No. 537-73-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0761R. | |
| Isoflurane | Isoflurane is a volatile anaesthetic. Isoflurane diminishs the effect of ROS activity. Isoflurane suppresses respiration. Isoflurane enables rapid anesthesia induction and emergence. Isoflurane protects against noise-induced hearing loss and tissue damage in mice. Isoflurane protects against renal ischemia and reperfusion injury and modulates leukocyte infiltration[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 26675-46-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-A0134. | |
| Isoforskolin | Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Coleonol B. CAS No. 64657-21-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6927. | |
| Isoginkgetin | Isoginkgetin is a pre-mRNA splicing inhibitor inhibitor. Isoginkgetin also inhibits activities of both Akt, NF-κB and MMP-9. Isoginkgetin inhibits the activity of the 20S proteasome, induces apoptosis and activates autophagy[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 548-19-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2117. | |
| Isoglobotriaose | Isoglobotriaose (Gala-3Galb-4Glc) is a glycosphingolipid found in mammalian tissues. Isoglobotriaose is an analogue of Globotriaose, the ganglioside derivatives of them locate in difference position of small intestine, isoglobotriaosylceramide is restricted to the nonepithelial residue, while globotriaosylceramide is in both compartments[1][2]. Uses: Scientific research. Category: Natural products. Alternative Names: Gala-3Galb-4Glc. CAS No. 41744-59-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N10526. | |
| (+)-Isolariciresinol | (+)-Isolariciresinol ((+)-Cyclolariciresinol) is a lignan that can be isolated from the roots of Bursera tonkinensis Guillaum and the needles of Pinus densiflora[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-Cyclolariciresinol. CAS No. 548-29-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-14579. | |
| Isoliensinine | Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from the seed embryo of Nelumbo nucifera, with anti-oxidant and anti-inflammatory and anti-cancer activities. Isoliensinine induces apoptosis in triple-negative human breast cancer cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6817-41-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0770. | |
| Isoliquiritigenin | Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza uralensis Fisch., which inhibits aldose reductase with an IC50 of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC50 of 24.7 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GU17; ISL; Isoliquiritigen; SJ000286237. CAS No. 961-29-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-N0102. | |
| Isolithocholic acid | Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3β-Hydroxy-5β-cholanic acid; 3-Epilithocholic acid; β-Lithocholic acid. CAS No. 1534-35-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0172B. | |
| Isolongifolene | Isolongifolene ((-)-Isolongifolene) is a tricyclic sesquiterpene isolated from Murraya koenigii. Isolongifolene attenuates Rotenone-induced oxidative stress, mitochondrial dysfunction and apoptosis through the regulation of PI3K/AKT/GSK-3β signaling pathways. Isolongifolene has antioxidant, anti-inflammatory, anticancer and neuroprotective properties[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Isolongifolene. CAS No. 1135-66-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N7363. | |
| Isolugrandoside | Isolugrandoside is a nature product. Isolugrandoside can be isolated from Digitalis davisiana Heywood[1]. Uses: Scientific research. Category: Natural products. CAS No. 221660-27-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N12084. | |
| Isomalt | Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Palatinitol. CAS No. 64519-82-0. Pack Sizes: 10 mM * 1 mL in Water; 1 g; 5 g; 10 g. Product ID: HY-N7393. | |
| Isomaltose | Isomaltose (6-O-α-D-Glucopyranosyl-D-glucose) is a glucose disaccharide. Isomaltose induces G-CSF secretion via heat-induced oxidative polymerization of glucose groups into high-molecular-weight compounds. Isomaltose modulates cecal bacterial cluster structure in mice. Isomaltose exhibits low glycemic index, slow hydrolysis, and prebiotic properties. Isomaltose reduces in vivo Cryptosporidium parvum colonization in neonatal mice. Isomaltose can be used for the research of Cryptosporidium parvum infection[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6-O-α-D-Glucopyranosyl-D-glucose; D-Isomaltose. CAS No. 499-40-1. Pack Sizes: 10 mM * 1 mL in Water; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N3018. | |
| Isomaltotriose | Isomaltotriose is a sugar from enzymic hydrolyzates of the dextran from Leuconostoc mesenteroides NRRL B-512[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3371-50-4. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0913A. | |
| Isomaltulose hydrate | Isomaltulose hydrate is an endogenous metabolite. Uses: Scientific research. Category: Signaling pathways. CAS No. 343336-76-5. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-128739. | |
| Isomannide | Isomannide (1,4:3,6-Dianhydromannitol) is a common intermediate compound and derivative of Isosorbide (HY-B1469). Some derivatives of isomannide have potent inhibitory effects on KLK5 and KLK7. Isomannide can be used in the research of HCV infection and KLK5/KLK7-related diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,4:3,6-Dianhydromannitol. CAS No. 641-74-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 50 g; 100 g; 500 g. Product ID: HY-W013827. | |
| Isomogroside V | Isomogroside V is a sweetener, which extracted from Siraitia grosvenorii (Swingle). Uses: Scientific research. Category: Natural products. CAS No. 1126032-65-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N6815. | |
| Isomyosmine | Isomyosmine is a nitrate reductase inhibitor. Isomyosmine is a nicotine related alkaloid present in solanecea plants containing nicotine. Isomyosmine can be used for research of inflammation and age-related disorders[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MyMD-1. CAS No. 53844-46-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W701069. | |
| Isoniazid | Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: INH; Isonicotinic acid hydrazide; Isonicotinic hydrazide. CAS No. 54-85-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-B0329. | |
| Isoniazid-d4 | Isoniazid-d4 is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: INH-d4; Isonicotinic acid hydrazide-d4; Isonicotinic hydrazide-d4. CAS No. 774596-24-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0329S. | |
| Isoniazid (Standard) | Isoniazid (Standard) is the analytical standard of Isoniazid. This product is intended for research and analytical applications. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: INH (Standard); Isonicotinic acid hydrazide (Standard); Isonicotinic hydrazide (Standard). CAS No. 54-85-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0329R. | |
| Isookanin | Isookanin can be used for the research of various illnesses including cancers, skin rashes, snake and insects bites, diabetes mellitus, diarrhoea. Isookanin acts as an anti-viral agent against HSV and varicella-zoster virus (VZV). Antioxidant activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1036-49-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N7677. | |
| Iso-Olomoucine | Iso-olomoucine is an inactive stereoisomer of the CDK5 inhibitor olomoucine with IC50 >1 mM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 101622-50-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-112382. | |
| Iso-OMPA | Iso-OMPA (Tetraisopropyl pyrophosphoramide) is a selective inhibitor of the irreversible butyrylcholinesterase (BuChE). Iso-OMPA enhances soman toxicity in rats associated with the inhibition of plasma carboxylesterase (CarbE)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tetraisopropyl pyrophosphoramide. CAS No. 513-00-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131922. | |
| Isoorientin | Isoorientin is a potent inhibitor of COX-2 with an IC50 value of 39 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Homoorientin. CAS No. 4261-42-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0767. | |
| Isopimpinellin | Isopimpinellin, an orally active compound isolated from Glomerella cingulata. Isopimpinellin blocks DNA adduct formation and skin tumor initiation by 7,12-dimethylbenz[a]anthracene. Isopimpinellin possesses anti-leishmania effect[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 482-27-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0769. | |
| Isoprenaline | Isoprenaline is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 7683-59-2. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108353. | |
| Isoprenaline hydrochloride | Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma[1][2][3][4][5][6]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Isoproterenol hydrochloride. CAS No. 51-30-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 1 g; 5 g. Product ID: HY-B0468. | |
| Isopropyl unoprostone | Isopropyl unoprostone (Unoprostone isopropyl ester), an analogue of a prostaglandin metabolite, is a potent large conductance Ca2+-activated K+ (BK) channels activator. Isopropyl unoprostone has antiglaucoma effects, lowering intraocular pressure (IOP) by increasing aqueous humour outflow. Isopropyl unoprostone can improve retinal sensitivity and the protection of central retinal sensitivity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Unoprostone isopropyl ester; UF-021. CAS No. 120373-24-2. Pack Sizes: 1 mg (23.55 mM * 100 μL in Methyl acetate). Product ID: HY-109545. | |
| (-)-Isoproterenol hydrochloride | (-)-Isoproterenol (Levisoprenalinel) hydrochloride is the R-isomer of Isoproterenol. (-)-Isoproterenol hydrochloride can reduce the cleavage of caspase 3 and TNFα levels in retinal endothelial cells (REC). (-)-Isoproterenol hydrochloride can be used for the study of diabetic retinopathy[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Levisoprenaline hydrochloride; Proternol L hydrochloride. CAS No. 5984-95-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-B1670A. | |
| (-)-Isopulegol | (-)-Isopulegol is prepared directly from the treatment of essential oil of citronella under solid supported acid catalysis and solvent-free microwave assisted ene-cyclisation. (-)-Isopulegol shows high activity in reacting with carbonyl compounds. (-)-Isopulegol can be used for antiviral activity research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 89-79-2. Pack Sizes: 10 g; 25 g; 50 g; 100 g. Product ID: HY-121206. | |
| Isoquercitrin | Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway[1]. Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Isoquercetin; Quercetin 3-glucoside. CAS No. 482-35-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N1445. | |
| Isoquercitrin (Standard) | Isoquercetin (Standard) is the analytical standard of Isoquercetin. This product is intended for research and analytical applications. Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway[1]. Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Isoquercetin (Standard); Quercetin 3-glucoside (Standard). CAS No. 482-35-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1445R. | |
| Isoquinoline-5-sulfonic acid (Standard) | Isoquinoline-5-sulfonic acid (Standard) is the analytical standard of Isoquinoline-5-sulfonic acid. This product is intended for research and analytical applications. Uses: Scientific research. Category: Signaling pathways. CAS No. 27655-40-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-W014447R. | |
| Isorhamnetin | Isorhamnetin is a flavonoid compound extracted from the Chinese herb Hippophae rhamnoides L. Isorhamnetin suppresses skin cancer through direct inhibition of MEK1 and PI3K. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3'-Methylquercetin. CAS No. 480-19-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0776. | |
| Isorhamnetin-3-O-glucoside | Isorhamnetin-3-O-glucoside is an orally active natural compound. Isorhamnetin 3-O-glucoside increases P-ERK, ERK, P-Akt (Ser473), P-PI3K, and PDX-1. Isorhamnetin 3-O-glucoside downregulates C/EBPα and inhibits lipase. Isorhamnetin 3-O-glucoside reduces lipids and inhibits obesity[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5041-82-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0777. | |
| Isorhapontigenin | Isorhapontigenin is an orally active dietary polyphenol. Isorhapontigenin acts as a potent antioxidant that reduces the production of reactive oxygen species (ROS). Isorhapontigenin promotes the binding of JUN to the AP-1 site on the SESN2 promoter, induces SESN2 transcription, triggers MAPK8-dependent JUN activation, and upregulates the expression of PPAR-α, PGC-1α and CPT-1A to facilitate fatty acid oxidation. Isorhapontigenin induces autophagy, apoptosis and preadipocyte differentiation; it inhibits tumor growth, cell invasion, NF-κB transcriptional activity, the PI3K/Akt signaling pathway, STAT1 phosphorylation and MMP-2 expression. Isorhapontigenin alleviates oxidative stress, inflammatory cytokine release and triglyceride accumulation; it increases intracellular ATP levels and promotes Nrf2 nuclear translocation. Isorhapontigenin improves insulin sensitivity in adipose tissue and glucose tolerance, and reduces postprandial blood glucose, insulin and free fatty acid levels. Isorhapontigenin is applicable to research on bladder cancer, liver injury, chronic obstructive pulmonary disease, acute lung injury and type 2 diabetes[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 32507-66-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N2593. | |
| Isorhoifolin | Isorhoifolin is a flavonoid glycoside from Hemistepta lyrata. Isorhoifolin displays an anti-leakage effect[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 552-57-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N3460. | |
| Isosakuranetin | Isosakuranetin is a flavanone flavonoid which can be found in the fruit of Citrus bergamia. Isosakuranetin is a TRPM3 blocker[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 480-43-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N2131. | |
| Isoschaftoside | Isoschaftoside, a C-glycosylflavonoid from Desmodium uncinatum root exudate, can inhibit the growth of germinated S. hermonthica radicles. Isoschaftoside reduces reactive oxygen species (ROS) and induces proliferation in senescent cells. Isoschaftoside activates autophagy. Isoschaftoside can be used for anti-tumor, anti-inflammatory, antioxidant, antihypertensive, hepatoprotective and nematicidal study[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 52012-29-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1458. | |
| Isoscutellarein | Isoscutellarein is a flavonoid compound that can be isolated from Wissadula periplocifolia (L.) C. Presl (Malvaceae)[1]. Uses: Scientific research. Category: Natural products. Alternative Names: 8-Hydroxyapigenin. CAS No. 41440-05-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N8363. | |
| Isosilybin A | Isosilybin A is a PPARγ agonist that can be isolated from silymarin. Isosilybin A activates extrinsic and intrinsic pathways of apoptosis through targeting of the Akt-NF-kB-AR axis. Isosilybin A can relieve the inflammatory response in the rosacea model via inhibiting Erk and p38 signaling pathways and M1 macrophage polarization, with its targets related to RELA and VEGFA. Isosilybin A has anti-prostate cancer (PCA) activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 142796-21-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-N7043. | |
| Isosilybin B | Isosilybin B is a flavonolignan. Isosilybin B can be isolated from Silybum marianum. Isosilybin B can regulate cell cycle-related proteins (e.g., reduce cyclins (D3, D1, A, E), Cdk4, Cdk2, Cdc25A), and activate Caspases (Caspase-9 and Caspase-3). Isosilybin B can promote Apoptosis, reduce androgen receptor (AR) and PSA. Isosilybin B has anticancer activity against prostate cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 142796-22-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7045. | |
| Isosorbide dinitrate | Isosorbide dinitrate (ISDN) is an NO donor that prevents LV remodeling and degradation of cardiac function following myocardial infarction (MI)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ISDN. CAS No. 87-33-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B1409. | |
| Isosorbide mononitrate | Isosorbide mononitrate (Isosorbide-5-mononitrate) is an orally active nitric acid compound used for angina pectoris by dilating blood vessels and lowering blood pressure. Isosorbide mononitrate increases the viability and proliferation of HUVECs by decreasing Apoptosis and elevated the expressions of vedf, kdrl, pdgfr in zebrafish embryos. Isosorbide mononitrate is promising for research of heart failure and coronary heart disease[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Isosorbide-5-mononitrate. CAS No. 16051-77-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B0642. | |
| Isosorbide mononitrate (Standard) | Isosorbide mononitrate (Standard) is the analytical standard of Isosorbide mononitrate. This product is intended for research and analytical applications. Isosorbide mononitrate (Isosorbide-5-mononitrate) is a nitric acid compound used for angina pectoris by dilating blood vessels and lowering blood pressure. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Isosorbide-5-mononitrate (Standard). CAS No. 16051-77-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0642R. | |
| Isostearic acid | Isostearic acid is a unique fatty acid. Isostearic acid promotes IL-1 release and Apoptosis. Isostearic acid has potent inflammatory properties. Isostearic acid can be used in pharmaceutical, personal care, and cosmetic applications[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2724-58-5. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W127433. | |
| Isosulfan blue | Isosulfan blue is a blue dye for the identification of lymph vessels during lymphangiography. Isosulfan blueis is used during sentinel lymph node biopsies in breast cancer. Isosulfan blue is possible to have an allergic reaction during breast cancer operations[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 68238-36-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107967. | |
| Isotachysterol 3 | Isotachysterol 3 is an analog of 1,25-dihydrox Vitamin D3. Isotachysterol 3 stimulates intestinal calcium transport and bone calcium mobilization in anephric rats[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 22350-43-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-130704. | |
| Isotanshinone IIA | Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 20958-15-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6650. | |
| Isotetrandrine | Isotetrandrine is a bioactive component in Stephania tetrandra[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 477-57-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6045. | |
| Isotretinoin | Isotretinoin (13-cis-Retinoic acid) is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 13-cis-Retinoic acid. CAS No. 4759-48-2. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-15127. | |
| Isovaleric acid | Isovaleric acid is an oral active short-chain fatty acid that inhibits osteoclast differentiation by stimulating AMPK phosphorylation and promotes colonic smooth muscle relaxation by activating the cAMP/PKA pathway. Isovaleric acid can be used in research on skeletal diseases (such as osteoporosis) and intestinal disorders[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 503-74-2. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W012980. | |
| Isovalerylcarnitine | Isovalerylcarnitine is a metabolite of leucine. Isovalerylcarnitine can specifically activate calpain in human neutrophils. Isovalerylcarnitine inhibits tumor cell proliferation and induces apoptosis. Elevated circulating levels of Isovalerylcarnitine are negatively correlated with reduced lung cancer risk[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 31023-24-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-113221. | |
| Isovanillin | Isovanillin is an aldehyde oxidase inhibitor[1]. Antispasmodic activities[2]. Antidiarrheal activities[3]. Uses: Scientific research. Category: Natural products. Alternative Names: 3-Hydroxy-4-methoxybenzaldehyde. CAS No. 621-59-0. Pack Sizes: 5 g; 10 g; 25 g; 50 g; 100 g; 250 g; 500 g; 1000 g. Product ID: HY-I0637. | |
| Isovitexin | Isovitexin is a flavonoid isolated from passion flower, Cannabis and, and the palm, possesses anti-inflammatory and anti-oxidant activities; Isovitexin acts like a JNK1/2 inhibitor and inhibits the activation of NF-κB. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Saponaretin; Homovitexin. CAS No. 38953-85-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0773. | |
| Isovitexin 2''-O-arabinoside | Isovitexin 2''-O-arabinoside is a flavonoid in plantlets of Avena sativa L.[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 53382-71-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N5114. | |
| Isoxaflutole | Isoxaflutole (Merlin) is the inhibitor for HPPD that blocks benzoquinone biosynthesis, and results in the bleaching of weeds. Isoxaflutole can be used as herbicide[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Merlin; RP-201772. CAS No. 141112-29-0. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116139. | |
| Isoxanthohumol | Isoxanthohumol is an orally active flavonoid compound. Isoxanthohumol has biological activities such as anti-tumor, anti-inflammatory, antioxidant, antiviral, antifungal, and inhibition of adipogenesis. Isoxanthohumol can induce apoptosis, autophagy, and migration of tumor cells. Isoxanthohumol is active against viruses such as HSV, BVDV, CMV, and Rhino. Isoxanthohumol can be used for the research of tumors, metabolic, and inflammatory diseases[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 521-48-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2584A. | |
| ISPA-28 | ISPA-28 is a specific plasmodial surface anion channel (PSAC) antagonist. ISPA-28 binds directly and reversibly to CLAG3[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1006335-39-2. Pack Sizes: 5 mg. Product ID: HY-109987. | |
| Ispinesib | Ispinesib is a specific inhibitor of kinesin spindle protein (KSP), with a Ki app of 1.7 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SB-715992; CK-0238273. CAS No. 336113-53-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50759. | |
| Ispronicline | Ispronicline (TC-1734), an orally active, brain-selective α4β2 nicotine acetylcholine receptor (nAChR) partial agonist, has shown memory-enhancing properties in rodents and a good tolerability profile. Ispronicline binds to the α4β2 nAChR with high affinity (Ki=11 nM) and is highly selective to other nAChRs such as α7 nAChR and α3β4 nAChR[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TC-1734; ACD3480. CAS No. 252870-53-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10063. | |
| Isradipine | Isradipine (PN 200-110) is an orally active and blood-brain barrier permeability L-type calcium channel blocker. Isradipine, as a powerful peripheral vasodilator, is a dihydropyridine calcium antagonist with selective actions on the heart as well as the peripheral circulation. Isradipine is a potentially viable neuroprotective agent for Parkinson's disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PN 200-110. CAS No. 75695-93-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0233. | |
| ISRIB | ISRIB is a brain-penetrant inhibitor of integrated stress response (ISR). Persistent activation of the ISR has been linked to the development of several neurological disorders as ISR represses translation through inhibiting eIF2B. ISRIB inhibits the ISR by promoting the nucleotide exchange activity of eIF2B and recovering the translation, and thus can be used for neurological disorders research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 548470-11-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12495A. | |
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