MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| N,N-Dimethylacetamide | N,N-Dimethylacetamide (DMAc) is an organic solvent with blood-brain transmissibility and an FDA-approved drug excipient. N, N-dimethylacetamide exerts anti-inflammatory activity by inhibiting the NF-κB signaling pathway. N, N-dimethylacetamide can be used in studies of weight gain caused by a high-fat diet and neuroinflammation in Alzheimer's disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DMAc. CAS No. 127-19-5. Pack Sizes: 100 mL; 10 mM * 1 mL in DMSO; 250 mL; 500 mL. Product ID: HY-W042416. |  |
| N,N-Dimethylglycine | N,N-Dimethylglycine (Dimethylglycine), a natural N-methylated glycine, is a nutrient supplement and acts as an NMDAR glycine site partial agonist. N,N-Dimethylglycine is a methyl donor that can improve immunity, act as an antioxidant to prevent oxidative stress, and scavenge excess free radicals. N,N-Dimethylglycine has antidepressant-like and surfactant effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dimethylglycine; DMG; N-Methylsarcosine. CAS No. 1118-68-9. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 5 g. Product ID: HY-Y0511. | |
| N,N-Dimethylglycine-d6 hydrochloride | N,N-Dimethylglycine-d6 (Dimethylglycine-d6) hydrochloride is the deuterium labeled N,N-Dimethylglycine hydrochloride (HY-W001158). N,N-Dimethylglycine (Dimethylglycine) hydrochloride, a natural N-methylated glycine, is a nutrient supplement and acts as an NMDAR glycine site partial agonist. N,N-Dimethylglycine hydrochloride is a methyl donor that can improve immunity, act as an antioxidant to prevent oxidative stress, and scavenge excess free radicals. N,N-Dimethylglycine hydrochloride has antidepressant-like and surfactant effects[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dimethylglycine-d6 hydrochloride; DMG-d6 hydrochloride; N-Methylsarcosine-d6 hydrochloride. CAS No. 347840-03-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W001158S. | |
| N,N'-Dimethylhydrazine dihydrochloride | N,N'-Dimethylhydrazine (1,2-Dimethylhydrazine) dihydrochloride is a tumor inducer that induces colon tumors in rodents[1][2]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: 1,2-Dimethylhydrazine dihydrochloride. CAS No. 306-37-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-W460407. | |
| N,N'-Dinitrosopiperazine | N,N'-Dinitrosopiperazine (1,4-Dinitrosopiperazine; DNP) is a carcinogen with specificity for nasopharyngeal epithelium and facilitates NPC metastasis. N,N'-Dinitrosopiperazine regulates multiple signaling pathways through protein phosphorylation, including LYRIC at serine 568[1]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: 1,4-Dinitrosopiperazine; DNP. CAS No. 140-79-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136433. | |
| N,N'-(Ethane-1,2-diyl)bis(2-bromoacetamide) | N,N'-(Ethane-1,2-diyl)bis(2-bromoacetamide) is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 4960-81-0. Pack Sizes: 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W614943. | |
| N-Nitrosoanatabine | (R,S)-N-Nitrosoanatabine (N-NAT) is a tobacco-specific nitrosamine (TSNA) that has been found in tobacco, tobacco products, and electronic cigarettes. The (S) enantiomer comprises approximately 80% of the N-NAT found in commercial and research cigarettes and smokeless tobacco.3 Unlike other TSNAs, N-NAT is not carcinogenic in rats when administered at doses of 1, 3, and 9 mmol/kg. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-NAT; N'-Nitrosoanatabine. CAS No. 887407-16-1. Pack Sizes: 1 mg. Product ID: HY-145476. | |
| N-Nitrosodibutylamine-d18 | N-Nitrosodibutylamine-d18 is the deuterium labeled N-Nitrosodibutylamine[1]. N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Nitroso-di-n-butylamine-d18. CAS No. 1219798-82-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-131113S. | |
| N-Nitrosodiethylamine | N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Diethylnitrosamine; DEN; DENA. CAS No. 55-18-5. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-N7434. | |
| N-Nitroso-N-methylurea | N-Nitroso-N-methylurea (NMU;MNU;NMH) is a potent carcinogen, mutagen and teratogenand. N-Nitroso-N-methylurea is a direct-acting alkylating agent that interacts with DNA. N-Nitroso-N-methylurea targets multiple animal organs to cause various cancer and/or degenerative disease. N-Nitroso-N-methylurea is also a precursor in the synthesis of diazomethane[1][2][3][4]. Uses: Scientific research. Category: Induced disease models products. CAS No. 684-93-5. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 2 g; 5 g. Product ID: HY-34758. | |
| N-Nitrosonornicotine | N-Nitrosonornicotine is a tobacco-specific nitrosamine that has carcinogenic and mutagenic activity, and it can induce micronuclei in C3A cells. N-Nitrosonornicotine can form DNA adducts[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (2S)-N'-Nitrosonornicotine. CAS No. 16543-55-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W683760. | |
| NNK | NNK is a nicotine-nitrosated derivative. NNK simultaneously stimulates Bcl2 phosphorylation exclusively at Ser70 and c-Myc at Thr58 and Ser62 through activation of both ERK1/2 and PKCα[1]. NNK induces survival and proliferation of human lung cancer cells. NNK can be used for lung cancer mice model structure[2]. Uses: Scientific research. Category: Induced disease models products. CAS No. 64091-91-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-126477. | |
| N,N'-Methylenebisacrylamide | N,N'-Methylenebisacrylamide (Bisacrylamide) is an orally active acrylamide dimer and crosslinker. N,N'-Methylenebisacrylamide increases CYP2E1, P53, cleaved caspase-3. N,N'-Methylenebisacrylamide promotes hepatic cancer. N,N'-Methylenebisacrylamide changes sperm abnormality rate and sperm count. N,N'-Methylenebisacrylamide decreases the number of various cells in the blood as well as induces liver and testicular damage. N,N'-Methylenebisacrylamide is used to prepare polyacrylamide gel[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bisacrylamide; MBA; Methylenebisacrylamide; N,N-Methylenebisacrylamide. CAS No. 110-26-9. Pack Sizes: 10 mM * 1 mL in DMSO; 50 g; 100 g. Product ID: HY-D0848. | |
| NNMTi | NNMTi is a potent nicotinamide N-methyltransferase (NNMT) inhibitor (IC50=1.2 μM) and selectively binds to the NNMT substrate-binding site residues[2]. NNMTi promotes myoblast differentiation in vitro and enhances fusion and regenerative capacity of muscle stem cells (muSCs) in aged mice[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 42464-96-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131042. | |
| N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate | N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate (TCFH) is a powerful coupling and derivatizing reagent for ester prodrug synthesis. N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate can be used for antitumor drugs before medicine research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TCFH. CAS No. 94790-35-9. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 50 g; 100 g; 500 g; 1 k g. Product ID: HY-W011556. | |
| N,N,N,N-Tetramethyl-p-phenylenediamine | N,N,N,N-Tetramethyl-p-phenylenediamine is an electron-donating aromatic diamine with a low ionization potential. N,N,N,N-Tetramethyl-p-phenylenediamine is a classic electron donor model compound for photochemical electron transfer studies[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 100-22-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g. Product ID: HY-W021358. | |
| N,N',N''-Triacetylchitotriose | N,N',N''-Triacetylchitotriose is a competitive Lysozyme inhibitor. N,N',N''-Triacetylchitotriose inhibits the activity of lysozyme. N,N',N''-Triacetylchitotriose reduces the fusion rate between lysozyme-conjugated liposomes and erythrocyte ghosts, and decreases the equilibrium fusion rate[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 38864-21-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-135072. | |
| N-Nonyldeoxynojirimycin | N-Nonyldeoxynojirimycin (NN-DNJ) is a deoxynojirimycin derivative with a hydrophobic long chain. N-Nonyldeoxynojirimycin is an orally active inhibitor of acid α-glucosidase (IC50: 0.42 μM) and α-1,6-glucosidase (IC50: 8.4 μM). N-Nonyldeoxynojirimycin has activities of inhibiting glycogen breakdown, anti-virus and anti-tumor. N-Nonyldeoxynojirimycin also has insecticidal effects, with an LD50 of 5 mM for adults of Bemisia tabaci[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NN-DNJ; Nonyl-DNJ. CAS No. 81117-35-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107532. | |
| NO2A-Azide trihydrochloride | NO2A-Azide (trihydrochloride)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Azide (trihydrochloride) can be used for conjugation of peptides and radionuclides. Uses: Scientific research. Category: Signaling pathways. CAS No. 2435782-92-4. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W717800A. | |
| Nobiletin | Nobiletin is a poly-methoxylated flavone from the citrus peel that improves memory loss. Nobiletin is a retinoid acid receptor-related orphan receptors (RORs) agonist. Nobiletin can reduce reactive oxygen species (ROS) levels in differentiated C2C12 myotubes and has anti-inflammation and anti-cancer properties, including anti-angiogenesis, anti-proliferation, anti-metastasis and induced apoptosis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 478-01-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0155. | |
| N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane | N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane is a powerful silylating reagent and can be utilized in chromatography research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25561-30-2. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 100 g; 500 g. Product ID: HY-123798. | |
| Nocardamine | Nocardamine (Deferrioxamine E)is an iron carrier/Iron chelator with antimicrobial activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Desferrioxamine E; Nocardamin. CAS No. 26605-16-3. Pack Sizes: 1 mg. Product ID: HY-124452. | |
| Nociceptin | Nociceptin, a heptadecapeptide, is the endogenous ligand of the nociceptin receptor, acting as a potent anti-analgesic. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Orphanin FQ. CAS No. 170713-75-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0183. | |
| Nocodazole | Nocodazole (Oncodazole) is a rapidly-reversible inhibitor of microtubule. Nocodazole binds to β-tubulin and disrupts microtubule assembly/disassembly dynamics, which prevents mitosis and induces apoptosis in tumor cells. Nocodazole inhibits Bcr-Abl. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Oncodazole; R17934. CAS No. 31430-18-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13520. | |
| Nocodazole (Standard) | Nocodazole (Standard) is the analytical standard of Nocodazole. This product is intended for research and analytical applications. Nocodazole (Oncodazole) is a rapidly-reversible inhibitor of microtubule. Nocodazole binds to β-tubulin and disrupts microtubule assembly/disassembly dynamics, which prevents mitosis and induces apoptosis in tumor cells. Nocodazole inhibits Bcr-Abl. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Oncodazole (Standard); R17934 (Standard). CAS No. 31430-18-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13520R. | |
| N-Octanoyl-L-homoserine lactone | N-Octanoyl-L-homoserine lactone is an autoinducer. It mainly serves as a key inter- and intra-species communication medium or "signal molecule" in Gram-negative bacteria. N-Octanoyl-L-homoserine lactone microparticles exhibit adjuvant potential when used in combination with various particulate vaccines[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: C8-HSL. CAS No. 147852-84-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124237A. | |
| n-Octyl β-D-glucopyranoside | n-Octyl-β-d-glucopyranoside is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins. n-Octyl-β-d-glucopyranoside can completely inhibit cavitation-induced cell lysis in vitro[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 29836-26-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-116285. | |
| NODAGA-RGD | NODAGA-RGD is a peptide that can be radiolabeled and used as a radiotracer for positron emission tomography (PET) diagnosis[1]. Uses: Scientific research. Category: Peptides. CAS No. 1321510-77-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10734. | |
| N,O-Dimethylhydroxylamine hydrochloride | N,O-Dimethylhydroxylamine hydrochloride is a biochemical reagent used as a terminal protecting group in oligosaccharide synthesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6638-79-5. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 100 g; 500 g. Product ID: HY-41074. | |
| NOD-IN-1 | NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors, NOD1 and NOD2, with IC50 of 5.74 μM and 6.45 μM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 132819-92-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100691. | |
| Nodinitib-1 | Nodinitib-1 (ML130;CID-1088438) is a NOD1 inhibitor with an IC50 of 0.56 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ML130; CID-1088438. CAS No. 799264-47-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18639. | |
| Nodulisporic acid A | Nodulisporic acid A (Compound 1a) is an insecticidal agent. Nodulisporic acid A can isolated from fermentations of Nodulisporium sp. Nodulisporic acid A has a potent insecticidal activity against the larvae of the blowfly and mosquito with LC50s of 0.5 and 0.3 ppm against A. aegypti and L. seracata, respectively. Nodulisporic acid A can be used for the development of insecticide[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 163120-03-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N16433. | |
| Nogapendekin alfa (his tag) | Nogapendekin alfa (his tag), a soluble protein subunit of a human interleukin (IL)-15 variant, is a superagonist of IL-15. Nogapendekin alfa (his tag) promotes the proliferation and viability of immune cells. Nogapendekin alfa (his tag) combines with Inbakicept (HY-P99661) at a ratio of 2:1, to form N-803 (Nogapendekin alfa inbakicept), an IL-15 cytokine antibody fusion protein. N-803 reduces tumor burden by activation of NK cells and CD8+ T cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IL-15N72D. CAS No. 1622189-43-8. Pack Sizes: 10 μg; 50 μg; 100 μg; 250 μg; 500 μg; 1 mg. Product ID: HY-P99759. | |
| Nolavetbart | Nolavetbart is an anti-Canlupfam IL31RA IgG2 κ monoclonal antibody[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VTQ-2101. CAS No. 2750248-93-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990713. | |
| N-Oleoyldopamine | N-Oleoyldopamine (OLDA) is an orally active TRPV1 activator and 5-LOX inhibitor with blood-brain barrier permeability. N-Oleoyldopamine excites histaminergic neurons in the tuberomammillary nucleus via a dopamine receptor mechanism, a process independent of TRPV1 and cannabinoid receptors. On one hand, N-Oleoyldopamine promotes the release of insulin and glucose-dependent insulinotropic polypeptide through a GPR119-dependent pathway to improve glucose tolerance; on the other hand, N-Oleoyldopamine improves left ventricular function and reduces myocardial infarction size by triggering the release of substance P and calcitonin gene-related peptide. N-Oleoyldopamine is used in studies related to glycemic abnormalities and myocardial ischemia-reperfusion injury[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OLDA. CAS No. 105955-11-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-108448. | |
| N-Oleoyl glycine | N-Oleoyl glycine is a lipoamino acid, which stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte. Uses: Scientific research. Category: Signaling pathways. CAS No. 2601-90-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-113204. | |
| Nω-Propyl-L-arginine | Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-omega-Propyl-L-arginine. CAS No. 137361-05-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102062. | |
| Nω-Propyl-L-arginine hydrochloride | Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) hydrochloride is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine hydrochloride displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-omega-Propyl-L-arginine hydrochloride. CAS No. 2321366-46-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102062A. | |
| Nomifensine | Nomifensine ((±)-Nomifensine) is a potent norepinephrine (NE) and dopamine (DA) reuptake inhibitor. Nomifensine inhibits uptake of NE, DA and 5-HT in rat brain synaptosomes, with IC50 values of 6.6 nM, 48 nM and 830 nM, and Ki values of 4.7 nM, 26 nM and 4000 nM, respectively. Nomifensine has antidepressant and analgesic effects. Nomifensine is used in neurodegenerative diseases, compound addiction, and pain research[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Nomifensine; Nomifensin. CAS No. 24526-64-5. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-B1110. | |
| Nomifensine maleate | Nomifensine ((±)-Nomifensine) maleate is a potent norepinephrine (NE) and dopamine (DA) reuptake inhibitor. Nomifensine maleate inhibits uptake of NE, DA and 5-HT in rat brain synaptosomes, with IC50 values of 6.6 nM, 48 nM and 830 nM, and Ki values of 4.7 nM, 26 nM and 4000 nM, respectively. Nomifensine maleate has antidepressant and analgesic effects. Nomifensine maleate is used in neurodegenerative diseases, compound addiction, and pain research[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Nomifensine maleate; Nomifensin maleate. CAS No. 32795-47-4. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-B1110A. | |
| Nomilin | Nomilin is a limonoid compound obtained from the extracts of citrus fruits. Nomilin is an anti-obesity and anti-hyperglycemic agent [1][2]. Uses: Scientific research. Category: Natural products. CAS No. 1063-77-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0547. | |
| Nonactin | Nonactin is a macrotetrolide antibiotic and mitochondrial uncoupler with antibacterial, insecticidal, and acaricidal activities. Nonactin acts as an ionophore for monovalent cations, including K+, and NH4+, and it can also inhibit the surface expression of endogenous HSP60. In addition, Nonactin can induce apoptosis in β-catenin mutant tumor cells and has anti-tumor activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ammonium ionophore I. CAS No. 6833-84-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N6790. | |
| Nonanoylcarnitine | Nonanoylcarnitine is a metabolite associated with chronic environmental exposure to polycyclic aromatic hydrocarbons (PAH) and fragmented QRS waves in acute myocardial infarction. Nonanoylcarnitine can be used as a potential biomarker for the metabolic outcome of PAH exposure and the prognosis of acute myocardial infarction[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: C9 carnitine. CAS No. 151109-67-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N11222. | |
| Nootkatone | Nootkatone, a neuroprotective agent from Vitis vinifera, has antioxidant and anti-inflammatory effects[1]. Nootkatone improves cognitive impairment in lipopolysaccharide-induced mouse model of Alzheimer's disease[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-Nootkatone. CAS No. 4674-50-4. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-N2195. | |
| Norartocarpetin | Norartocarpetin is a tyrosinase inhibitor. Norartocarpetin has strong tyrosinase inhibitory activity with an IC50 value of 0.47 μM. Norartocarpetin as an antibrowning agent can be used for the research of food systems. Norartocarpetin also has a significant anticancer activity in lung carcinoma cells (NCI-H460) with an IC50 value of 22 μM. Norartocarpetin has antiproliferative effects are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion in human lung carcinoma cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 520-30-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N10503. | |
| Norathyriol | Norathyriol (Mangiferitin) is a natural metabolite of Mangifera. Norathyriol inhibits α-glucosidase in a noncompetitive manner with an IC50 of 3.12?μM[1]. Norathyriol inhibits PPARα, PPARβ, and PPARγ with IC50s of 92.8 μM, 102.4 μM, and 153.5 μM, respectively[2]. Antioxidant, anticancer, antimicrobial, anti-inflammatory, anti-bacterial activities. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mangiferitin. CAS No. 3542-72-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N1029. | |
| nor-Binaltorphimine | nor-Binaltorphimine (Norbinaltorphimine; NorBNI) is a selective, long-acting competitive antagonist of the κ-opioid receptor. nor-Binaltorphimine blocks κ-opioid receptor-mediated analgesic effects, and inhibits butorphanol-induced changes in κ-opioid receptor binding kinetics, desensitization and down-regulation. nor-Binaltorphimine suppresses specific opioid withdrawal symptoms, precipitates withdrawal behaviors in butorphanol-dependent rats, and serves as a molecular probe for studying κ-opioid receptor-agonist interactions. nor-Binaltorphimine is applicable to research related to neurological disorders such as pain[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Norbinaltorphimine; NorBNI. CAS No. 105618-26-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-117040. | |
| Norbinaltorphimine dihydrochloride | Norbinaltorphimine dihydrochloride (nor-Binaltorphimine dihydrochloride; nor-BNI dihydrochloride) is a selective, long-acting competitive antagonist of the κ-opioid receptor. Norbinaltorphimine dihydrochloride blocks κ-opioid receptor-mediated analgesic effects, and inhibits butorphanol-induced changes in κ-opioid receptor binding kinetics, desensitization and down-regulation. Norbinaltorphimine dihydrochloride suppresses specific opioid withdrawal symptoms, precipitates withdrawal behaviors in butorphanol-dependent rats, and serves as a molecular probe for studying κ-opioid receptor-agonist interactions. Norbinaltorphimine dihydrochloride is applicable to research related to neurological disorders such as pain[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: nor-Binaltorphimine dihydrochloride; nor-BNI dihydrochloride. CAS No. 113158-34-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-100903. | |
| Norcaesalpinin E | Norcaesalpinin E, a C-17-norcassane-type diterpene found in Caesalpinia crista, is a Plasmodium falciparum growth inhibitor with an IC50 of 90 nM. Norcaesalpinin E induces dose-dependent growth inhibition of Plasmodium falciparum. Norcaesalpinin E can be used for the research of malaria[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 854038-96-3. Pack Sizes: 1 mg. Product ID: HY-N7583. | |
| Norcholic acid | Norcholic acid is a normal minorbile C23 bile acid having four side chain and exsits in human urine and meconium. Norcholic acid can become prominent under certain pathological conditions. Norcholic acid is efficiently absorbed from intestine and quickly excreted into the bile but not into urine[1]. Uses: Scientific research. Category: Natural products. CAS No. 60696-62-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N9457. | |
| Nordihydrocapsaicin | Nordihydrocapsaicin, an analog of Capsaicin (HY-10448), is an orally active compound with pungent properties and anti-cancer activities, which is found in fresh and processed peppers. Nordihydrocapsaicin can cause a burning sensation when consumed[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 28789-35-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0449. | |
| Norepinephrine | Norepinephrine (Levarterenol; L-Noradrenaline) is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors[1][2][3][4]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Levarterenol; L-Noradrenaline. CAS No. 51-41-2. Pack Sizes: 100 mg; 500 mg. Product ID: HY-13715. | |
| Norepinephrine bitartrate monohydrate | Norepinephrine (Levarterenol; L-Noradrenaline) bitartrate monohydrate is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors[1][2][3][4]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Levarterenol bitartrate monohydrate; L-Noradrenaline bitartrate monohydrate. CAS No. 108341-18-0. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-13715B. | |
| Norepinephrine hydrochloride | Norepinephrine (Levarterenol; L-Noradrenaline) hydrochloride is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors[1][2][3][4]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Levarterenol hydrochloride; L-Noradrenaline hydrochloride. CAS No. 329-56-6. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg. Product ID: HY-13715A. | |
| Norepinephrine (Standard) | Norepinephrine (Standard) is the analytical standard of Norepinephrine. This product is intended for research and analytical applications. Norepinephrine (Levarterenol; L-Noradrenaline) is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Levarterenol (Standard); L-Noradrenaline (Standard). CAS No. 51-41-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13715R. | |
| Norepinephrine tartrate | Norepinephrine (Levarterenol; L-Noradrenaline) tartrate is a potent adrenergic receptor (AR) agonist. Norepinephrine tartrate activates α1, α2, β1 receptors[1][2][3][4]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Levarterenol tartrate; L-Noradrenaline tartrate. CAS No. 51-40-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-13715C. | |
| Norethisterone enanthate | Norethisterone enanthate is a long-acting parenteral progestogen. Norethisterone enanthate is orally active[1][2][3]. Norethisterone enanthate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Norigest. CAS No. 3836-23-5. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-A0285. | |
| Noreugenin | Noreugenin is a phenolic compound found in Calea uniflora Less. Noreugenin inhibits myeloperoxidase activity and reduces levels of proinflammatory cytokines IL-1β and IL-17A levels in LPS (HY-D1056)-induced murine pleurisy model. Noreugenin reduces apoptosis and necrosis. Noreugenin reduces lipid peroxidation, and antioxidant enzyme (CAT, SOD, GST) activity. Noreugenin exhibits anti-inflammatory and antioxidant effects. Noreugenin can be used for the research of inflammatory conditions, such as pleurisy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1013-69-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N3029. | |
| Norfloxacin | Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase. Uses: Scientific research. Category: Induced disease models products. Alternative Names: MK-0366. CAS No. 70458-96-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 5 g; 10 g. Product ID: HY-B0132. | |
| Norfluoxetine | Norfluoxetine is the active metabolite of antidepressant Fluoxetine (HY-B0102). Norfluoxetine is a selective inhibitor for serotonin uptake[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 83891-03-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135556. | |
| Norfluoxetine hydrochloride | Norfluoxetine hydrochloride is an active N-demethylated metabolite of Fluoxetine. Fluoxetine is a selective serotonin (5-HT) reuptake inhibitor that is metabolized to Norfluoxetine hydrochloride by cytochrome P450 (CYP) 2D6, CYP2C19, and CYP3A4. Norfluoxetine hydrochloride inhibits 5-HT uptake and inhibits CaV3.3 T current (IC50 = 5 μM). Norfluoxetine hydrochloride has anticonvulsant activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 57226-68-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W011235. | |
| Norflurazon | Norflurazon (SAN 9789) is a bleaching herbicide. Norflurazon can block carotenoid biosynthesis by inhibiting phytoene desaturase activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SAN 9789. CAS No. 27314-13-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-114849. | |
| Norgestimate | Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive[1][2]. Norgestimate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 35189-28-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W013172. | |
| Norgestimate metabolite Norelgestromin | Norgestimate metabolite Norelgestromin (17-Deacetyl norgestimate) is a metabolite of Norgestimate (HY-W013172). Norgestimate metabolite Norelgestromin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 17-Deacetyl norgestimate; 17-Deacylnorgestimate. CAS No. 53016-31-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-G0018. | |
| Norgestomet | Norgestomet is a compound with progesterone receptor agonist activity. The synthetic product has high purity and agonist activity on the progesterone receptor, while its 17β-isomer is inactive. Uses: Scientific research. Category: Signaling pathways. CAS No. 25092-41-5. Pack Sizes: 500 μg. Product ID: HY-121677. | |
| Norgestrel-d6 | Norgestrel-d6 is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives. Norgestrel-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2376035-98-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0257S1. | |
| Norharmane | Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC50 values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Norharman; β-Carboline. CAS No. 244-63-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-W008566. | |
| Noribogaine hydrochloride | Noribogaine hydrochloride is an orally active, blood-brain barrier permeable SERT inhibitor (IC50=50-300 nM) and hERG channel blocker. Noribogaine hydrochloride enhances serotonergic transmission, activates the κ-opioid receptor (OPRK) G protein signaling pathway and inhibits β-arrestin recruitment. Meanwhile, Noribogaine hydrochloride blocks the μ-opioid receptor (OPRM) signaling pathway as well as ion channels associated with cardiac repolarization. Noribogaine hydrochloride induces neuritogenesis, upregulates GDNF mRNA expression, and modulates opioid tolerance. Noribogaine hydrochloride reduces alcohol-seeking behavior in experimental animals, and is widely used in studies related to depression, addiction, alcoholism, and cardiotoxicity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 110514-35-7. Pack Sizes: 500 μg; 1 mg. Product ID: HY-136832. | |
| Normetanephrine | Normetanephrine is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Hypertension[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Normetanephrine; DL-Normetanephrine. CAS No. 97-31-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-113517. | |
| Normetanephrine-d3 hydrochloride | Normetanephrine-d3 (hydrochloride) is the deuterium labeled Normetanephrine hydrochloride. Normetanephrine ((±)-Normetanephrine) hydrochloride is the O-methylated metabolite of norepinephrine (NE)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Normetanephrine-d3 hydrochloride; DL-Normetanephrine-d3 hydrochloride; (Rac)-Normetanephrine-d3 hydrochloride. CAS No. 1085333-97-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W008794S. | |
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