MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Acetamiprid | Acetamiprid is a neonicotinoid insecticide used worldwide. Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist, and is shown to be associated with neuromuscular and reproductive disorders[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 135410-20-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-B0823. |  |
| Acetazolamide | Acetazolamide is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX. Acetazolamide has diuretic, antihypertensive and anti-gonococcal activities[1][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 59-66-5. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B0782. | |
| Acetazolamide impurity 2 | Acetazolamide impurity 2 (NSC 231656) is an impurity of Acetazolamide. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 231656. CAS No. 60320-32-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W168956. | |
| Acetazolamide sodium | Acetazolamide sodium is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX. Acetazolamide sodium has diuretic, antihypertensive and anti-gonococcal activities[1][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1424-27-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B0782A. | |
| Acetic acid-13C2 sodium | Acetic acid-13C2 is a stable isotope labeled compound with biomarker and metabolic tracking activity. Acetic acid-13C2 is often used in biochemical research for the analysis of metabolic pathways. Acetic acid-13C2 is also used in medical imaging and compound development to improve the understanding of biological processes. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anhydrous sodium acetate-13C2. CAS No. 56374-56-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W749209. | |
| Acetoacetic acid | Acetoacetic acid is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Acetoacetic acid induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes. Acetoacetic acid can be used to study metabolic diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 541-50-4. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-112540. | |
| Acetobromo-α-D-galactose | Acetobromo-α-D-galactose is a brominating agent, serving as an important intermediate in the synthesis of various glycosides and oligosaccharides[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3068-32-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W028813. | |
| Acetobromo-α-D-glucuronic acid methyl ester, 98% | Acetobromo-α-D-glucuronic acid methyl ester, 98% is a glucuronosyl donor. Acetobromo-α-D-glucuronic acid methyl ester, 98% is applicable to the synthesis of other compounds[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acetobromo-alpha-D-glucuronic acid methyl ester, 98%. CAS No. 21085-72-3. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W008125. | |
| Acetohexamide | Acetohexamide is an orally active first-generation sulfonylurea agent used in research related to type 2 diabetes and cancer. Acetohexamide exerts reductase activity in human erythrocytes. Acetohexamide stimulates the pancreas to secrete insulin. Acetohexamide inhibits ATP-sensitive potassium channels in the β cells of the pancreas. Acetohexamide can inhibit the formation of circular chemorepellent induced defects (CCIDs) in lymphendothelial cell (LEC) monolayers. Acetohexamide inhibits markers of epithelial-to-mesenchymal-transition and migration. Acetohexamide suppresses the synthesis of 12(S)-HETE. Acetohexamide can potentiate hypoglycaemic action[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 968-81-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B0881. | |
| Acetosyringone | Acetosyringone is a phenolic compound from wounded plant cells, enables virA gene which encodes a membrane-bound kinase to phosphorylate itself and activate the virG gene product, which stimulates the transcription of other vir genes and itself[1]. Acetosyringone enhances efficient Dunaliella transformation of Agrobacterium strains[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2478-38-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 1 g. Product ID: HY-W009884. | |
| Acetyl-6-formylpterin | Acetyl-6-formylpterin (Ac-6-FP) is a hapten that covalently binds to MR1 through residue Lys43 of the protein, resulting in protein upregulation. Acetyl-6-formylpterin (Ac-6-FP) can be used in the study of inflammation[1]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Ac-6-FP. CAS No. 29769-49-1. Pack Sizes: 10 mM * 1 mL in DMF; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124004. | |
| Acetyl-Calpastatin(184-210)(human) | Acetyl-Calpastatin(184-210)(human) is a potent, selective and reversible calpain inhibitor with Ki values of 0.2 nM and 6 μM for μ-calpain and cathepsin L, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 123714-50-1. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1081. | |
| (±)-Acetylcarnitine chloride | (±)-Acetylcarnitine chloride (Acetyl dl-carnitine chloride) is a weak cholinergic agonist with cholinergic properties. (±)-Acetylcarnitine chloride is an important intermediate in lipid metabolism[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acetyl dl-carnitine chloride. CAS No. 2504-11-2. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100907. | |
| Acetylcellulose | Acetylcellulose is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cellulose monoacetate. CAS No. 9004-35-7. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-W133892. | |
| Acetylcholine chloride | Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent and BBB-permeable cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs)[1][2]. Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACh chloride. CAS No. 60-31-1. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-B0282. | |
| Acetylcholine chloride (Standard) | Acetylcholine (chloride) (Standard) is the analytical standard of Acetylcholine (chloride). This product is intended for research and analytical applications. Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent and BBB-permeable cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs)[1][2]. Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACh chloride (Standard). CAS No. 60-31-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0282R. | |
| Acetylcholine-d4 chloride | Acetylcholine-d4 (chloride) is the deuterium labeled Acetylcholine chloride. Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent and BBB-permeable cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs)[1][2]. Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACh-d4 chloride. CAS No. 344298-94-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0282S. | |
| Acetylcholinesterase, Electric eel | Acetylcholinesterase, Electric eel is a cholinergic enzyme that is mainly found in neuromuscular junctions and cholinergic chemical synapses and is often used in biochemical research. Acetylcholinesterase, Electric eel can catalyze the decomposition or hydrolysis of acetylcholine and some other choline esters that act as neurotransmitters into acetic acid and choline. The main function of Acetylcholinesterase, Electric eel is to terminate neuronal transmission and signal conduction between synapses to prevent ACh diffusion and activation of nearby receptors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9000-81-1. Pack Sizes: 500 U. Product ID: HY-P2860A. | |
| Acetylcholinesterase, Fly head | Acetylcholinesterase, Fly head (ACHE; EC 3.1.1.7) is a cholinergic enzyme mainly found in neuromuscular junctions and cholinergic type chemical synapses used in biochemical research. Acetylcholinesterase, Fly head catalyzes the breakdown or hydrolysis of acetylcholine and some other choline esters that act as neurotransmitters into acetate and choline. Acetylcholinesterase, Fly head's main role is to terminate neuronal transmission and signaling between synapses to prevent ACh spread and activation of nearby receptors[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACHE; EC 3.1.1.7. CAS No. 9000-81-1. Pack Sizes: 50 mg; 100 mg; 200 mg. Product ID: HY-P2860. | |
| Acetyl-CoA synthetase | Acetyl-CoA synthetase (ACS) is a key enzyme that catalyzes the conversion of acetate to acetyl-CoA (Ac-CoA). Acetyl-CoA synthetase catalyzes the formation of thioester bonds between coenzyme A and carboxylic acids, while simultaneously hydrolyzing ATP into AMP and pyrophosphate[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACS. CAS No. 9012-31-1. Pack Sizes: 5 mg. Product ID: HY-P2827. | |
| Acetyl coenzyme A lithium | Acetyl-coenzyme A (Acetyl-CoA) lithium is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A lithium, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A lithium is also a key precursor of lipid synthesis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acetyl-CoA lithium. CAS No. 32140-51-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113596A. | |
| Acetyl coenzyme A trilithium | Acetyl-coenzyme A (Acetyl-CoA) trilithium is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A trilithium regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A trilithium is also a key precursor of lipid synthesis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acetyl-CoA trilithium. CAS No. 75520-41-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-114293A. | |
| Acetyl Coenzyme A trisodium | Acetyl-coenzyme A (Acetyl-CoA) trisodium is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A trisodium, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A trisodium is also a key precursor of lipid synthesis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acetyl-CoA trisodium. CAS No. 102029-73-2. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113596. | |
| Acetylcysteine | Acetylcysteine (N-Acetylcysteine) is a mucolytic agent that can cross the blood-brain barrier, which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine ??is the most stable form of cysteine ??during drug delivery and can be used in disulfidptosis studies[1][2][3][4][5][6][7][8]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Acetylcysteine; N-Acetyl-L-cysteine; NAC. CAS No. 616-91-1. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-B0215. | |
| Acetylcysteine-d3 | Acetylcysteine-d3 is the deuterium labeled Acetylcysteine. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies[1][2][3][4][5][6][7][8]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Acetylcysteine-d3; N-Acetyl-L-cysteine-d3; NAC-d3. CAS No. 131685-11-5. Pack Sizes: 5 mg. Product ID: HY-B0215S. | |
| Acetyl decapeptide-3 | Ac-Decapeptide is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient[1]. Uses: Scientific research. Category: Peptides. CAS No. 935288-50-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P3047. | |
| Acetyldigitoxin | Acetyldigitoxin (Digitoxin 3'''-Acetate) is a cardiac glycoside. Acetyldigitoxin can come from the leaves of Digitalis species. Acetyldigitoxin reduces the heart rate and can be used for cardiac failure rasearch[1][2]. Uses: Scientific research. Category: Natural products. Alternative Names: Digitoxin 3'''-Acetate. CAS No. 1111-39-3. Pack Sizes: 1 mg. Product ID: HY-16022. | |
| Acetylene-linker-Val-Cit-PABC-MMAE | Acetylene-linker-Val-Cit-PABC-MMAE (LCB14-0602) consists the ADCs linker (Acetylene-linker-Val-Cit-PABC) and potent tubulin inhibitor (MMAE). Acetylene-linker-Val-Cit-PABC-MMAE (LCB14-0602) is a agent-linker conjugate for ADC. Acetylene-linker-Val-Cit-PABC-MMAE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LCB14-0602. CAS No. 1411977-95-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19812. | |
| Acetyl hexapeptide-1 acetate | Acetyl hexapeptide-1 (Melitane) acetate is a biomimetic peptide that mimics the activity of α-melanocyte-stimulating hormone (α-MSH). Acetyl hexapeptide-1 acetate can regulate muscle contraction, thereby reducing facial expression lines. Acetyl hexapeptide-1 acetate is one of the components of anti-aging skin care essences targeting dynamic wrinkles. Acetyl hexapeptide-1 acetate can be used in studies related to mild photo-aged facial skin and premature graying of hair[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Melitane acetate. CAS No. 2828433-36-7. Pack Sizes: 50 mg; 100 mg. Product ID: HY-P5220A. | |
| Acetylisoniazid | Acetylisoniazid is a primary Isoniazid (HY-B0329) metabolite mediated by N-acetyltransferase (NAT). Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AcINH. CAS No. 1078-38-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100048. | |
| Acetyl-L-carnitine | Acetyl-L-carnitine (O-Acetyl-L-carnitine; ALCAR) is an orally active mitochondrial energy metabolism regulator and neuroprotectant that can penetrate the blood-brain barrier. Acetyl-L-carnitine selectively enters cells and the brain through the organic cation transporter OCTN2. Acetyl-L-carnitine can participate in fatty acid β-oxidation, promote acetylcholine synthesis, regulate mitochondrial function and inhibit oxidative stress as an acetyl donor. Acetyl-L-carnitine exerts its activity by enhancing energy metabolism, protecting neurons and improving synaptic plasticity. Acetyl-L-carnitine is mainly used in the study of neurodegenerative diseases and metabolic disorder-related diseases such as neonatal hypoxic-ischemic brain damage, Alzheimer's disease, and depression[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: O-Acetyl-L-carnitine; ALCAR. CAS No. 3040-38-8. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-113218. | |
| Acetyl-L-carnitine-d3 hydrochloride | Acetyl-L-carnitine-d3 (O-Acetyl-L-carnitine-d3) hydrochloride is the deuterium labeled Acetyl-L-carnitine hydrochloride (HY-B0762). Acetyl-L-carnitine (O-Acetyl-L-carnitine; ALCAR) hydrochloride is an orally active mitochondrial energy metabolism regulator and neuroprotectant that can penetrate the blood-brain barrier. Acetyl-L-carnitine hydrochloride selectively enters cells and the brain through the organic cation transporter OCTN2. Acetyl-L-carnitine hydrochloride can participate in fatty acid β-oxidation, promote acetylcholine synthesis, regulate mitochondrial function and inhibit oxidative stress as an acetyl donor. Acetyl-L-carnitine hydrochloride exerts its activity by enhancing energy metabolism, protecting neurons and improving synaptic plasticity. Acetyl-L-carnitine hydrochloride is mainly used in the study of neurodegenerative diseases and metabolic disorder-related diseases such as neonatal hypoxic-ischemic brain damage, Alzheimer's disease, and depression[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: O-Acetyl-L-carnitine-d3 hydrochloride. CAS No. 1334532-17-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0762S. | |
| Acetyl-L-carnitine hydrochloride | Acetyl-L-carnitine (O-Acetyl-L-carnitine; ALCAR) hydrochloride is an orally active mitochondrial energy metabolism regulator and neuroprotectant that can penetrate the blood-brain barrier. Acetyl-L-carnitine hydrochloride selectively enters cells and the brain through the organic cation transporter OCTN2. Acetyl-L-carnitine hydrochloride can participate in fatty acid β-oxidation, promote acetylcholine synthesis, regulate mitochondrial function and inhibit oxidative stress as an acetyl donor. Acetyl-L-carnitine hydrochloride exerts its activity by enhancing energy metabolism, protecting neurons and improving synaptic plasticity. Acetyl-L-carnitine hydrochloride is mainly used in the study of neurodegenerative diseases and metabolic disorder-related diseases such as neonatal hypoxic-ischemic brain damage, Alzheimer's disease, and depression[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: O-Acetyl-L-carnitine hydrochloride; ALCAR hydrochloride. CAS No. 5080-50-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-B0762. | |
| Acetyl phosphate lithium potassium | Acetyl phosphate lithium potassium is an endogenous metabolic product. Acetyl phosphate lithium potassium is a key substance in bacterial metabolic regulation, particularly in Lysine acetylation, and plays an important role in bacterial responses to environmental stress and adaptive reactions[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 94249-01-1. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128730. | |
| Acetyl podocarpic acid anhydride | Acetyl podocarpic acid anhydride is a potent, semisynthetic liver X receptor(LXR) agonist derived from extracts of the mayapple. Acetyl podocarpic acid anhydride has the potential to be useful for the prevention and research of atherosclerosis, especially in the context of low HDL levels[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acetylpodocarpic dimer; APD. CAS No. 344327-48-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-125772. | |
| Acetylshikonin | Acetylshikonin is an oral active anti-cancer, anti-inflammatory, antioxidant, anti-fertility, antibacterial, and neuroprotective agent. Acetylshikonin is a inhibitor of acetylcholinase (AChE) (IC50=34.6 μM) and nonselective cytochrome P450. Acetylshikonin can induce Apoptosis and Autophagy in cancer cells. Acetylshikonin regulates blood glucose, liver fat metabolism, and renal fibrosis, and is used in the study of diabetes, diabetic nephropathy (DN), obesity, and nonalcoholic fatty liver disease (NAFLD)[1][2][3][4][5][6][7][8][9]. Uses: Scientific research. Category: Signaling pathways. CAS No. 24502-78-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2181. | |
| Acetylthiocholine iodide | Acetylthiocholine iodide can be used as a substrate for certain enzymes, such as cholinesterase, etc., and can be used to determine the activity level of these enzymes. In addition, the compound is used in some medical research, for example in the fields of neuroscience and organ physiology. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S-Acetylthiocholine iodide; ATCh iodide. CAS No. 1866-15-5. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g. Product ID: HY-D0904. | |
| Acetyl zingerone | Acetyl zingerone is an analog of Zingerone (HY-14621). Acetyl zingerone downregulates the expression of ROS metabolism-related genes, fibroblast senescence-related genes, keratinocyte differentiation-related genes, and IL-17A target genes. Acetyl zingerone inhibits the activities of MMP-1, MMP-3, and MMP-12, as well as the activation of NLRP3 inflammasome, pyroptosis (pyroptosis), ferroptosis (ferroptosis), cartilage destruction, and UVA-induced cyclobutane pyrimidine dimer formation. Acetyl zingerone upregulates the expression of collagen, proteoglycan, extracellular matrix glycoprotein, Notch pathway, and GPX4 gene, activates Nrf2 and HO-1, induces extracellular matrix synthesis and PINK1/Parkin-mediated mitophagy (mitophagy), and promotes chondrocyte survival. Acetyl zingerone alleviates the progression of osteoarthritis in mice. Acetyl zingerone can be used in research related to skin aging, inflammatory skin diseases, osteoarthritis, melanoma, and non-melanoma skin cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 30881-23-3. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-164826. | |
| Ac-Exatecan | Ac-Exatecan is acetylation-modified Exatecan (HY-13631). Exatecan is a common toxin component in ADC preparation (ADC cytotoxin) and an inhibitor of DNA topoisomerase I (IC50 = 2.2 μM). Exatecan has antitumor activity. Exatecan can be used as a payload for ADC. Exatecan is effective against P-glycoprotein mediated multi-drug resistant cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2922852-48-8. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-79490. | |
| Ac-FLTD-CMK | Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1 (IC50 of 46.7 nM), caspases-4 (IC50 of 1.49 μM), caspases-5 (IC50 of 329 nM), and caspases-11 , but not the apoptotic caspases such as caspase-3[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2376255-48-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-111675. | |
| Ac-Gly-BoroPro | Ac-Gly-BoroPro is a selective FAP inhibitor with a Ki of 23 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 886992-99-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-101801. | |
| ACH-000143 | ACH-000143 is a potent and orally active melatonin receptor agonist, with EC50 values of 0.06 nM and 0.32 nM for MT1 and MT2, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2225836-30-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138626. | |
| AChE-IN-23 | AChE-IN-23 (compound 3h) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 48.3 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6297-14-9. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-W077226. | |
| Ac-H-FluNox | Ac-H-FluNox is an acetylated cell-compatible prodrug of H-FluNox (HY-D2339). Ac-H-FluNox undergoes intracellular hydrolysis of its acetyl group by esterases to generate H-FluNox, which then undergoes a deoxygenation reaction with labile heme to form a fluorescent product. Ac-H-FluNox detects fluctuations of labile heme in living cells, acute labile heme release upon nitric oxide stimulation, and accumulation of labile heme following inhibition of heme export proteins[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2897614-60-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-D2869. | |
| ACHM-025 | ACHM-025 is a prodrug, which is selectively activated by AKR1C3 to a nitrogen mustard DNA alkylating agent. ACHM-025 can be used for the research of cancer, such as leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2377718-85-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-172314. | |
| ACHN-975 TFA | ACHN-975 TFA is a selective LpxC inhibitor and exhibits a subnanomolar LpxC inhibitory activity. ACHN-975 TFA is against a wide range of gram-negative bacterias with low MIC values (≤1 μg/mL)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1410809-37-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19936A. | |
| ACHP Hydrochloride | ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an IC50 of 8.5 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IKK-2 Inhibitor VIII. CAS No. 406209-26-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13060. | |
| AChRα(97-116) | AChRα(97-116) is a synthetic peptide corresponding to the 97-116 region of the rat acetylcholine receptor α-subunit, and also an inducer of autoimmune diseases. AChRα(97-116) can be used in studies related to experimental autoimmune myasthenia gravis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 663154-30-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5766. | |
| Achyranthoside D | Achyranthoside D is a triterpene saponin from Achyranthes root[1]. Uses: Scientific research. Category: Natural products. CAS No. 168009-91-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N7952. | |
| ACI-19626 | ACI-19626 (TDP-43-IN-2) is a TDP-43 aggregation inhibitor that can be used in the research of neurodegenerative diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TDP-43-IN-2. CAS No. 3033951-93-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163575. | |
| Acid Ceramidase-IN-1 | Acid Ceramidase-IN-1 is orally active and blood-brain barrier penetrant acid ceramidase (AC, ASAH-1) inhibitor (hAC IC50=0.166 μM). Acid Ceramidase-IN-1 reduces AC activity, accumulates ceramide species (Cer (d18:0/16:0), Cer (d18:1/16:0)), and decreases sphingosine levels. Acid Ceramidase-IN-1 can be used for the study of severe neurological lysosomal storage diseases (LSDs) such as Gauchers disease (GD) and Krabbes disease (KD)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2415225-30-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141866. | |
| Acid orange 7 | Acid Orange 7 (Orange II; D&C Orange NO. 4) is an azo dye widely used in the textile, food and cosmetic industries. Acid Orange 7 is mainly used as a colorant by combining with fibers and other substances through azo bonds. Acid Orange 7 has a maximum absorption wavelength at 484-485 nm, and the concentration is measured using a UV-visible spectrophotometer. Acid Orange 7 is difficult to degrade and has a certain degree of toxicity. It is often used to study various sewage treatment technologies and photocatalytic degradation reactions, and to evaluate the removal effects of different treatment methods on organic pollutants[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Orange II; D&C Orange NO. 4. CAS No. 633-96-5. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg. Product ID: HY-N1442. | |
| Acid-PEG4-C2-Boc | Acid-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the inhibition of mTOR[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1835759-85-7. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-23167. | |
| Acid Red 94 sodium | Acid Red 94 sodium, a synthetic fluorescein derivative, is a deep red dye primarily composed of 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. It is widely used as an ophthalmic diagnostic agent to detect dry or damaged cells on the ocular surface. Acid Red 94 sodium exhibits antitumor activity and can inhibit Friend Leukemia Virus (FLV) infection through photodynamic action. Additionally, Acid Red 94 sodium can inhibit Aβ aggregation through light irradiation. Acid Red 94 sodium holds potential for use in cancer, viral infections, and neurodegenerative disease research[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 632-69-9. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-D0214. | |
| Acid Red sodium | Acid Red is a class of synthetic dyes commonly used in the textile, paper and ink industries. They are in the category of acid dyes, which means they are water soluble and have acidic properties. Acid Red dye produces bright, vibrant colors that don't fade easily, but are not as durable as some other dyes. They can be used to dye a wide variety of fibers including wool, silk and nylon, as well as paper and leather. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acid Violet 19; Acid fuchsin sodium. CAS No. 3244-88-0. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 50 g; 100 g. Product ID: HY-D0854. | |
| Acid Yellow 9 monosodium salt | Acid Yellow 9 monosodium salt is an azo dye, degraded by Pseudomonas fluorescens as sole source of carbon, nitrogen and energy for the bacterium[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hydrogen 4-aminoazobenzene-3,4'-disulphonate sodium salt. CAS No. 74543-21-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-D0705. | |
| Ac-IEPD-AFC | Ac-IEPD-AFC is a substrate of Granzyme B[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1135417-31-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1092. | |
| Ac-IEPD-CHO | Ac-IEPD-CHO is a reversible granzyme B inhibitor with a Ki of 80 nM[1]. Ac-IEPD-CHO is also a caspase-8 inhibitor[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 352520-90-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10149. | |
| Ac-?IETD-?CHO | Ac- IETD- CHO is a potent, reversible inhibitor of granzyme B and caspase-8. Ac- IETD- CHO inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failure. Ac- IETD- CHO also inhibits cytotoxic T lymphocytes induced cell death[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 191338-86-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-113963. | |
| Acifluorfen-methyl | Acifluorfen-methyl is an inhibitor of the heme and chlorophyll biosynthetic enzyme protoporphyrinogen oxidase (Protox). Acifluorfen-methyl is a photobleaching herbicide[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 50594-67-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147365. | |
| Acipimox | Acipimox (K-9321), a nicotinic acid analogue, is an antilipolytic compound. Acipimox stimulates leptin releas, inhibits lipolysis and suppresses systemic levels of free fatty acids (FFAs) and improves insulin sensitivity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: K-9321. CAS No. 51037-30-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0283. | |
| Acitretin | Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. Acitretin also can be used for the research of Alzheimers disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 10-1670. CAS No. 55079-83-9. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0107. | |
| Acivicin | Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AT-125; U-42126. CAS No. 42228-92-2. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg. Product ID: HY-W016586. | |
| Acivicin hydrochloride | Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AT-125 hydrochloride; U-42126 hydrochloride. CAS No. 161922-40-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W016586A. | |
| Ac-KQKLR-AMC TFA | Ac-KQKLR-AMC TFA is a substrate peptide of Cathepsin S fluorescently labeled with AMC (Ex/Em=354 nm/442 nm). Ac-KQKLR-AMC TFA can be used to measure Cathepsin S activity)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cathepsin S substrate TFA. CAS No. 2237216-84-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P5378A. | |
| Aclacinomycin A | Aclacinomycin A (Aclarubicin) is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A is an inhibitor of topoisomerase I and II. Aclacinomycin A inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Aclarubicin. CAS No. 57576-44-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N2306. | |
| Ac-LEHD-AFC | Ac-LEHD-AFC is a fluorescent substrate for caspase-9, can be used to assess the activity of caspase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 210345-03-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1093. | |
| Ac-LEHD-AMC | Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 292633-16-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1652. | |
| Ac-LEHD-pNA | Ac-LEHD-pNA is a biological active peptide. (Caspase-9 substrate; pNA (4-nitroaniline)-derived caspase substrates are widely used for the colorimetric detection of various caspase activities. Cleavage of pNA peptides by caspases generates pNA that is monitored colorimetrically at ~405 nm. pNA has maximum absorption around 408 nm.). Uses: Scientific research. Category: Peptides. CAS No. 921771-40-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P5348. | |
| Ac-LEVD-CHO | Ac-LEVD-CHO is a caspase-4 inhibitor. Ac-LEVD-CHO is a peptide with the sequence of Ac-Leu-Glu-Val-Asp-al[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 402832-01-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-136727. | |
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