MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Aclidinium Bromide | Aclidinium Bromide (LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist. Aclidinium Bromide has the potential for chronic obstructive pulmonary disease (COPD) research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LAS 34273; LAS-W 330. CAS No. 320345-99-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14144. |  |
| Aclimostat | Aclimostat (ZGN-1061) is a potent inhibitor of the MetAP2 enzyme and displays favorable efficacy and safety in preclinical studies. ZGN-1061 produced similar efficacy as beloranib for weight loss, improvements in metabolic parameters in a mouse model of obesity and insulin resistance, and concordant changes in gene transcription in HepG2 cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZGN-1061. CAS No. 2082752-83-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-114196. | |
| Acloproxalap | Acloproxalap is a quinoline-based aldehyde scavenger that can be used in studies of diseases with toxic aldehyde accumulation, such as inflammatory diseases of the eye and skin, respiratory diseases such as pneumonia, organ diseases, and viral infection-related syndromes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ADX-629. CAS No. 1824609-67-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147240. | |
| Ac-Lys-AMC | Ac-Lys-AMC (Hexanamide), also termed MAL, is a fluorescent substrate for histone deacetylase HDACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 156661-42-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-128919. | |
| Ac-Nle-Pro-Nle-Asp-AMC | Ac-Nle-Pro-Nle-Asp-AMC is a specific substrate for 26S proteasome. Ac-Nle-Pro-Nle-Asp-AMC can be used for the 26S proteasome caspase-like activity analysis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 355140-49-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P2016. | |
| Acoltremon | Acoltremon (WS-12; AR-15512) is a potent and selective TRPM8 agonist, the menthol derivative, as a cooling agent. Acoltremon shows analgesic effect, and can be used in chronic neuropathic pain research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: WS-12; AR-15512; AVX-012. CAS No. 68489-09-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-108449. | |
| Aconitic acid | Aconitic acid (NSC 7616) is an organic acid, and can be isolated from seeds of Brassica oleracea var. acephala (kale). Aconitic acid has antifungal activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 7616. CAS No. 499-12-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg. Product ID: HY-W016814A. | |
| Acoramidis | Acoramidis (AG10) is an orally active and selective kinetic stabilizer of WT and V122I-TTR (transthyretin). Acoramidis (AG10) is used in the study for transthyretin amyloidosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AG10. CAS No. 1446711-81-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109165. | |
| Acoramidis hydrochloride | Acoramidis (AG10) hydrochloride is an orally active and selective kinetic stabilizer of WT and V122I-TTR (transthyretin). Acoramidis (AG10) hydrochloride is used in the study for transthyretin amyloidosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AG10 hydrochloride. CAS No. 2242751-53-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109165A. | |
| Acoziborole | Acoziborole (SCYX-7158) is an effective, safe and orally active antiprotozoal agent for the research of human african trypanosomiasis (HAT). In the T. b. brucei S427 strain, the MIC value for SCYX-7158 is 0.6 μg/mL[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SCYX-7158; AN5568. CAS No. 1266084-51-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-19910. | |
| ACP-105 | ACP-105 is an orally available, selective amd potent androgen receptor modulator (SARM), with pEC50s of 9.0 and 9.3 for AR wild type and T877A mutant, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 899821-23-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112256. | |
| ACP3 ligand 1 | ACP3 ligand 1 is a ligand of Acid Phosphatase 3 (ACP3, ACPP). ACP3 ligand 1 interacts with ACP3 expressed on the surface of tumor cells for in vivo pharmaco-delivery applications[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3084148-32-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-176567. | |
| ACP-5862 | ACP-5862 is a major active, circulating, pyrrolidine ring-opened metabolite of Acalabrutinib with an IC50 of 5.0 nM for Bruton tyrosine kinase (BTK). ACP?5862 is a weak time?dependent inactivator of CYP3A4 and CYP2C8. Acalabrutinib is an orally active, irreversible, and highly selective BTK inhibitor, with an IC50 of 3 nM and EC50 of 8 nM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2230757-47-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-135334. | |
| Ac-PAL-AMC | Ac-PAL-AMC is a fluorogenic substrate specific for 20S proteasome LMP2/β1i activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1431362-79-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-123052. | |
| Ac-RFAAKAA-COOH | Ac-RFAAKAA-COOH is a cysteine-containing polypeptide with a reactive lysine residue, and serves as a substrate for covalent modification and chemical reactivity assays. Ac-RFAAKAA-COOH forms stable covalent adducts with isothiocyanates, resulting in peptide depletion over time. Ac-RFAAKAA-COOH acts as a model peptide in direct peptide reactivity assays, where its chemical reactivity is evaluated via fluorescamine-based free amine assays. Ac-RFAAKAA-COOH can be used in studies related to allergic contact dermatitis and skin sensitization[1][2]. Uses: Scientific research. Category: Peptides. CAS No. 845727-63-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P10940. | |
| Acridine Orange 10-Nonyl Bromide | Acridine Orange 10-Nonyl Bromide is a fluorescent probe for cardiolipin (λex: 489 nm, λem: 525 nm). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Nonylacridine orange. CAS No. 75168-11-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0993. | |
| Acridine Orange base | Acridine Orange base is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells in green for detection by fluorescence microscopy. Acridine Orange base fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644), also can be used in cell cycle assays[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 494-38-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-D0952. | |
| Acridine Orange hydrochloride | Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 65-61-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg. Product ID: HY-101879. | |
| Acriflavine | Acriflavine (Acriflavinium chloride) is a fluorescent acridine dye that can be used to label nucleic acid. Acriflavine is an antiseptic agent. Acriflavine is a potent HIF-1 inhibitor that prevents the dimerization of HIF-1α and HIF-1β subunits. Acriflavine inhibits the interaction between monocarboxylate transporter 4 (MCT4) and Basigin. Acriflavine is used in cancer research, such as breast cancer, brain tumor and chronic myeloid leukemia. Acriflavine is a potent papain-like protease (PLpro) inhibitor, which inhibits SARS-CoV-2[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acriflavinium chloride 3,6-Acridinediamine mix. CAS No. 8048-52-0. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-100575. | |
| Acrizanib | Acrizanib (LHA510) is a VEGFR-2 inhibitor, with an IC50 of 17.4 nM for BaF3-VEGFR-2[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LHA510. CAS No. 1229453-99-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109020. | |
| Ac-RLR-AMC | Ac-RLR-AMC (Ac-Arg-Leu-Arg-AMC) is a fluorogenic substrate for the 26S proteasome (Ex/Em: 380/440-460 nm). AMC is released upon cleavage, and its fluorescence can be used to quantify the trypsin-like activity of 26S proteasomes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ac-Arg-Leu-Arg-AMC. CAS No. 929903-87-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-135070. | |
| Acrylodan | Acrylodan, reacted with thiols, is sensitive to the local environmental dipolarity and dynamics within the binding pocket surrounding Cys34[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 86636-92-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-W040230. | |
| ACSL5-IN-2 | ACSL5-IN-2 (Compound B) is an Acyl CoA synthetase 5 (ACSL5) inhibitor. ACSL5-IN-2 can block the conversion of long-chain fatty acids (such as palmitic acid and oleic acid) into acyl-CoA, and intervene in the fatty acid metabolism pathway. ACSL5-IN-2 can inhibit cancer cells growth. ACSL5-IN-2 can be used for the research of cancer and metabolic disease, such as colon cancer and dysfunction-associated Steatohepatitis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3098297-74-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-177705. | |
| ACSL5-IN-3 | ACSL5-IN-3 (page 115 line 11) is an ACSL5 inhibitor. ACSL5-IN-3 can be used for research of tumours, digestive system diseases, and endocrine and metabolic diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3098298-22-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-177850. | |
| ACSS2-IN-2 | ACSS2-IN-2 is an acyl-CoA synthetase short-chain family member 2 (ACSS2) inhibitor. ACSS2-IN-2 can inhibit ACSS2 activity with an IC50 value of 3.8 nM. ACSS2-IN-2 can be used for the research of several diseases, such as viral infection, metabolic disorders, neuropsychiatric diseases, inflammatory/autoimmune conditions and cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2332820-04-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148104. | |
| ACT017 | ACT017 is a Fab fragment of humanized anti-GPVI monoclonal antibody. ACT017 inhibits collagen-induced platelet aggregation. ACT017 has the potential for the research of acute ischemic stroke[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2101829-58-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99644. | |
| ACT-1004-1239 | ACT-1004-1239 is a potent, selective, orally active CXCR7 antagonist with an IC50 value of 3.2 nM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2178049-58-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-142617. | |
| ACT-1016-0707 | ACT-1016-0707 (Compound 49) is an orally active and selective LPA1 receptor antagonist. ACT-1016-0707 can be used for the research of fibrotic diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LPA1 receptor antagonist 2. CAS No. 2569467-78-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138453. | |
| ACT-451840 | ACT-451840 is an orally active, potent and low-toxicity compound, showing activity against sensitive and resistant plasmodium falciparum strains. ACT-451840 targets all asexual blood stages of the parasite, has a rapid onset of action. ACT-451840 behaves in a way similar to artemisinin derivatives, with very rapid onset of action and elimination of parasite. ACT-451840 can be used for the research of malarial[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1984890-99-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111817. | |
| ACT-462206 | ACT-462206 is an orally active and potent dual Orexin 1/Orexin 2 receptor antagonist with IC50s of 60 nM (Orexin 1) and 11 nM (Orexin 2), respectively. ACT-462206 exhibits brain penetration properties, and can be used for insomnia, stress/anxiety-related disorders and addiction research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1361321-96-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101834. | |
| ACT-660602 | ACT-660602 is an orally active antagonist of chemokine receptor (CXCR3) with an IC50 value of 204 nM. ACT-660602 inhibits T-cell migration and shows efficacy in acute lung ingury model. ACT-660602 can be used for autoimmune diseases research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1646267-59-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151096. | |
| Actein | Actein, a triterpene glycoside, shows an inhibitory effect on cancer cells, which is isolated from the rhizomes of Cimicifuga foetida. Actein suppresses cell proliferation, induces autophagy and apoptosis through promoting ROS/JNK activation, and blunting AKT pathway in bladder cancer. Actein has little toxicity in vivo[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18642-44-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6872. | |
| ACTH (11-24) | ACTH (11-24) is an adrenocorticotropic hormone (ACTH) receptor antagonist. ACTH (11-24) is a fragment of adrenocorticotropic and induces cortisol release. ACTH (11-24) can be used for the research of central nervous system[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adrenocorticotropic Hormone (11-24). CAS No. 4237-93-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1558. | |
| ACTH (1-13) | ACTH (1-13) is a 13-aa peptide, with cytoprotective effects in the model of ethanol induced gastric lesions in rats. Uses: Scientific research. Category: Peptides. Alternative Names: Adrenocorticotropic Hormone (1-13). CAS No. 22006-64-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1555. | |
| ACTH (1-16) (human) | ACTH (1-16) (human) (Adrenocorticotropic hormone (1-16)) is an ACTH fragment. ACTH (1-16) (human) improves cardiovascular function and survival in experimental hemorrhagic shock[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adrenocorticotropic hormone (1-16). CAS No. 5576-42-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P3068. | |
| Actinine | Actinine is a metabolic and pro-atherogenic intermediate with oral activity. Actinine acts as a substrate for the yeaW/X microbial enzyme complex to generate trimethylamine (TMA). Actinine accelerates atherosclerosis development in a gut microbe-dependent manner. Actinine can be used for the research of atherosclerosis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: γ-Butyrobetaine; Deoxycarnitine. CAS No. 407-64-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-113270. | |
| Actinomycin X2 (purity≥85%) | Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp., shows strong inhibition of MRSA with a minimum inhibitory concentration (MIC) value of 0.25 μg/mL. Actinomycin X2 can be used for cancer and bacterial infection[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Actinomycin V (purity≥85%). CAS No. 18865-48-0. Pack Sizes: 1 mg. Product ID: HY-125747. | |
| Actinonin | Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Actinonin. CAS No. 13434-13-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113952. | |
| Ac-Trp-Glu-His-Asp-AMC | Ac-Trp-Glu-His-Asp-AMC (AC-WEHD-AMC) is a potent fluorogenic substrate of caspase-1[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AC-WEHD-AMC. CAS No. 189275-74-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4547. | |
| Acumapimod | Acumapimod (BCT197) is an orally active p38 MAP kinase inhibitor, with an IC50 of less than 1 μM for p38α. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BCT197. CAS No. 836683-15-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16715. | |
| Ac-VEID-AFC | Ac-VEID-AFC is a caspase-6 fluorogenic substrate, and can be used in the caspase 6 activity assay[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 210345-01-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5983. | |
| Ac-WLA-AMC | Ac-WLA-AMC is a specific 20S constitutive proteasome β5 fluorogenic substrate[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1104011-59-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-123051. | |
| ACY-1083 | ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor with an IC50 of 3 nM and is 260-fold more selective for HDAC6 than all other classes of HDAC isoforms. ACY-1083 effectively reverses chemotherapy-induced peripheral neuropathy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1708113-43-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111791. | |
| ACY-738 | ACY-738 is a potent, selective and orally-bioavailable HDAC6 inhibitor, with an IC50 of 1.7 nM; ACY-738 also inhibits HDAC1, HDAC2, and HDAC3, with IC50s of 94, 128, and 218 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1375465-91-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19327. | |
| ACY-775 | ACY-775 is a potent and selective inhibitor of the of histone deacetylase 6 (HDAC6) with an IC50 of 7.5?nM[1][2]. ACY775 also inhibits metallo-β-lactamase domain-containing protein?2 (MBLAC2)[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1375466-18-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19328. | |
| ACY-957 | ACY-957 is an orally active and selective inhibitor of HDAC1 and HDAC2, with IC50s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1609389-52-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104008. | |
| Acyclovir | Acyclovir (Aciclovir) is a potent, orally active antiviral agent. Acyclovir has antiherpetic activity with IC50 values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir induces cell cycle perturbation and apoptosis. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Aciclovir; Acycloguanosine. CAS No. 59277-89-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg. Product ID: HY-17422. | |
| Acyclovir-d4 | Acyclovir-d4 is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC50 of 0.85 μM), HSV-2 (IC50 of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination[1][2][3]. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia[4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Aciclovir-d4; Acycloguanosine-d4. CAS No. 1185179-33-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-17422S1. | |
| Acyclovir sodium | Acyclovir (Aciclovir) sodium is a potent, orally active antiviral agent. Acyclovir sodium has antiherpetic activity with IC50 values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir sodium induces cell cycle perturbation and apoptosis. Acyclovir sodium prevents bacterial infections during induction therapy for acute leukaemia[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Aciclovir sodium; Acycloguanosine sodium. CAS No. 69657-51-8. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-17422A. | |
| Acyclovir (Standard) | Acyclovir (Standard) is the analytical standard of Acyclovir. This product is intended for research and analytical applications. Acyclovir (Aciclovir) is a potent, orally active antiviral agent. Acyclovir has antiherpetic activity with IC50 values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir induces cell cycle perturbation and apoptosis. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Aciclovir (Standard); Acycloguanosine (Standard). CAS No. 59277-89-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17422R. | |
| Acyclovir triphosphate sodium (100 mM) | Acyclovir triphosphate (Synonyms: AcycloGTP) sodium is a Acyclovir (HY-17422) derivative that competitively inhibits viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate (dGTP). Acyclovir triphosphate (sodium) (100 mM) is an inhibitor of HIV-1 reverse transcriptase. Acyclovir triphosphate (sodium) (100 mM) causes termination of viral DNA synthesis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AcycloGTP sodium (100 mM). CAS No. 221119-43-3. Pack Sizes: 1 mg (100 mM * 20 μL in water); 5 mg (100 mM * 100 μL in water). Product ID: HY-142028A. | |
| Acyl-CoA oxidase | Acyl-CoA oxidase (ACO) is a peroxisomal catalyst. Acyl-CoA oxidase acts as a key rate-limiting enzyme in the process of peroxisomal fatty acid β-oxidation. Acyl-CoA oxidase participates in lipid catabolism and phytohormone biosynthesis pathways[1]. Uses: Scientific research. Category: Enzymes. Alternative Names: ACO. CAS No. 61116-22-1. Pack Sizes: 100 U; 500 U; 1 KU. Product ID: HY-E70009. | |
| Acyl coenzyme A synthetase | Acyl coenzyme A synthetase (ACS), namely acetyl coenzyme A synthetase, is often used in biochemical research. Acyl coenzyme A synthetase can catalyze the activation of fatty acids by coenzyme A through a two-step thioesterification reaction to produce acyl coenzyme A, and then participate in a variety of anabolic and catabolic lipid metabolism pathways, and participate in the TCA cycle in aerobic respiration[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACS. CAS No. 9013-18-7. Pack Sizes: 100 U. Product ID: HY-P2832. | |
| Ac-YVAD-CHO | Ac-YVAD-CHO (L-709049) is a potent, reversible, specific tetrapeptide interleukin-lβ converting enzyme (ICE) inhibitor with mouse and human Ki values of 3.0 and 0.76 nM. Ac-YVAD-CHO is also a caspase-1 inhibitor. Ac-YVAD-CHO can suppress the production of mature IL-lβ[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-709049. CAS No. 143313-51-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-120019. | |
| Ac-YVAD-cmk | Ac-YVAD-cmk (Caspase-1 Inhibitor II) is a selective caspase-1 (IL-1beta converting enzyme, ICE)) inhibitor with neuroprotective and anti-inflammatory effects. Ac-YVAD-cmk effectively suppresses the expression of IL-1β and IL-18. Ac-YVAD-cmk inhibits pyroptosis in many diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Caspase-1 Inhibitor II. CAS No. 178603-78-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16990. | |
| AD1058 | AD1058 is an orally active, selective, and BBB-permeable inhibitor of ATR (IC50: 1.6 nM). AD1058 exhibits anticancer activity by inhibiting tumor cell proliferation, inducing cell cycle arrest, and promoting apoptosis. AD1058 is suitable for research on advanced malignancies and brain metastases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2907782-78-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159480. | |
| AD-5584 | AD-5584 is an ACSS2 inhibitor with blood-brain permeability. AD-5584 can significantly reduce lipid storage, reduce colony formation, and increase cell death. AD-5584 has antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2306525-79-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161116. | |
| AD80 | AD80, a multikinase inhibitor, inhibits RET, RAF,SRCand S6K, with greatly reduced mTOR activity. Uses: Scientific research. Category: Signaling pathways. CAS No. 1384071-99-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101963. | |
| AD-8007 | AD-8007 is an acetyl CoA synthase 2 (ACSS2) inhibitor that can cross the blood-brain barrier. AD-8007 can significantly reduce lipid storage and cell colony formation in vitro models, and increase tumor cell death. AD-8007 has anti-cancer activity and can be used in the research of breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1497439-74-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161117. | |
| ADA disodium | ADA (disodium) is a buffer salt derived from ADA (adenosine deaminase) and is widely used in biochemical research, especially in the preparation of enzyme buffers. Uses: Scientific research. Category: Signaling pathways. CAS No. 41689-31-0. Pack Sizes: 5 g; 10 g; 25 g; 50 g. Product ID: HY-D0855A. | |
| Adagrasib | Adagrasib (MRTX849) is a potent, orally-available, and mutation-selective covalent inhibitor of KRAS G12C with potential antineoplastic activity. Adagrasib covalently binds to KRAS G12C at the cysteine at residue 12, locks the protein in its inactive GDP-bound conformation, and inhibits KRAS-dependent signal transduction[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MRTX849. CAS No. 2326521-71-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-130149. | |
| Adakitug | Adakitug (BMS-986253) is a CHO-expressed human antibody targeting CXCL8/IL-8. Adakitug contains huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 144.94 kDa. The isotype control for Adakitug can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Adakitug exhibits anti-tumor activity and can be applied in tumor research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-986253; HuMax-IL-8. CAS No. 2231258-73-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990598. | |
| Adalimumab | Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor?α (TNF-α). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anti-Human TNF-alpha, Human Antibody; ABBV-3373 Antibody. CAS No. 331731-18-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P9908. | |
| Adamantane-carboxylic acid | Adamantane-carboxylic acid is a compound with inhibitory activity against microorganisms. Although its specific target has not been clearly defined, it can inhibit Gram-positive bacteria and some Gram-negative bacteria. It forms a 1-monoacylglycerol derivative through a direct reaction with glycidol, and exerts its antibacterial effect by mechanisms such as altering the permeability of the bacterial cell membrane. This compound can be used in the research of antibacterial agents in the food and cosmetic industries to reduce harmful microbial flora and extend the shelf life of products[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 828-51-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 50 g; 100 g; 250 g; 500 g; 1 k g. Product ID: HY-W016473. | |
| ADAMTS-5 Inhibitor | ADAMTS-5 Inhibitor is a potent ADAMTS-5 (aggrecanase-2) inhibitor, with an IC50 of 1.1 μM. ADAMTS-5 Inhibitor shows >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 929634-33-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-114996. | |
| Adapalene | Adapalene (CD271), a third-generation synthetic retinoid, is widely used for the research of acne. Adapalene is a potent RAR agonist, with AC50s of 2.3 nM, 9.3 nM, and 22 nM for RARβ, RARγ, RARα, respectively. Adapalene also inhibits the enzymatic activity of GOT1 in a non-competitive manner. Adapalene exhibits anti-tumor activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CD271. CAS No. 106685-40-9. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg. Product ID: HY-B0091. | |
| Adaphostin | Adaphostin (NSC 680410), the adamantyl ester of AG957, is a potent p210bcr/abl inhibitor (IC50=14 μM). Adaphostin induces apoptosis in T-lymphoblastic human leukemia cell lines (IC50 ranging from 17 to 216 nM). Adaphostin has significant and selective activity against chronic and acute myeloid leukemia cells. Adaphostin increased the level of reactive oxygen species (ROS) within CLL B cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 680410. CAS No. 241127-58-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103275. | |
| Adaptaquin | Adaptaquin is a BBB-penetrable HIF-PHDs inhibitor. Adaptaquin has anti-inflammatory and neuroprotective effects. Adaptaquin can effectively inhibit lipid peroxidation, maintain mitochondrial function, and reduce neuronal death. Adaptaquin can be used in the research of nervous system diseases such as Parkinson's disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 385786-48-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101449. | |
| ADAR1-IN-1 | ADAR1-IN-1 is a potent ADAR1 inhibitor. ADAR1-IN-1 significantly suppressed DU-145 cell proliferation (IC50 = 1.11 μM), clonogenicity, migration, and invasion, arrests cell cycle, and induces apoptosis. ADAR1-IN-1 safely and effectively inhibits tumor growth. ADAR1-IN-1 can be used for the study of prostate cancer (PCa)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2734853-87-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-175243. | |
| Adarotene | Adarotene is an effective apoptosis inducer, which surprisingly produces DNA damage and exhibites a potent antiproliferative activity on a large panel of human tumor cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ST1926. CAS No. 496868-77-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-14808. | |
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