MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Adavivint | Adavivint (SM04690; Lorecivivint) is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SM04690; Lorecivivint. CAS No. 1467093-03-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109049. |  |
| Adavosertib | Adavosertib (AZD-1775; MK-1775) is a potent Wee1 inhibitor with an IC50 of 5.2 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD1775; MK-1775. CAS No. 955365-80-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-10993. | |
| ADDA 5 hydrochloride | ADDA 5 hydrochloride is a partial non-competitive inhibitor of cytochrome c oxidase (CcO), with IC50s of 18.93 μM and 31.82 μM for purified CcO from human glioma and bovine heart, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 473268-46-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-U00448. | |
| Adecatumumab | Adecatumumab (Anti-Human EPCAM Recombinant Antibody; MT201) is a full human monoclonal antibody of the IgG1 isotype, targeting human EpCAM. Adecatumumab is expressed in almost all adenocarcinomas, and its activity is not dependent of K-Ras status[1][2]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: MT 201; Anti-Human EPCAM Recombinant Antibody. CAS No. 503605-66-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99278. | |
| Adenine | Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis[1][2][3]. Uses: Scientific research. Category: Induced disease models products. CAS No. 73-24-5. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 25 g. Product ID: HY-B0152. | |
| Adenine-13C | Adenine-13C is the 13C labeled Adenine[1]. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis[2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenine-8-C13; 9H-Purin-6-amine-8-13C. CAS No. 86967-48-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0152S1. | |
| Adenine hemisulfate | Adenine hemisulfate (6-Aminopurine hemisulfate), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hemisulfate acts as a chemical component of DNA and RNA. Adenine hemisulfate also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis[1][2]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: 6-Aminopurine hemisulfate; Vitamin B4 hemisulfate. CAS No. 321-30-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g. Product ID: HY-B0152B. | |
| Adenosine | Adenosine (Adenine riboside), a ubiquitous and BBB-permeable endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenine riboside; D-Adenosine. CAS No. 58-61-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-B0228. | |
| Adenosine-13C10 | Adenosine-13C10 (Adenine riboside-13C10; D-Adenosine-13C10) is 13C-labeled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenine riboside-13C10; D-Adenosine-13C10. CAS No. 1887761-94-5. Pack Sizes: 1 mg; 10 mg. Product ID: HY-B0228S13. | |
| Adenosine-13C5 | Adenosine-13C5 is the 13C labeled Adenosine[1]. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation[2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenine riboside-13C5; D-Adenosine-13C5. CAS No. 159496-13-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-B0228S1. | |
| Adenosine-15N5 | Adenosine-15N5 (Adenine riboside-15N5; D-Adenosine-15N5) is the 15N labled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenine riboside-15N5; D-Adenosine-15N5. CAS No. 168566-57-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0228S11. | |
| Adenosine 2',3'-cyclic phosphate sodium | Adenosine 2',3'-cyclic phosphate sodium is a 2',3'-cyclic purine nucleotide. Adenosine 2',3'-cyclic phosphate sodium is deaminated by the adenosine deaminase. Adenosine 2',3'-cyclic phosphate sodium can be degrade to 2'-AMP and 3'-AMP[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 37063-35-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg. Product ID: HY-W011256. | |
| Adenosine-2'-monophosphate | Adenosine-2'-monophosphate (2'-AMP) is converted by extracellular 2,3'-CAMP. Adenosine-2'-monophosphate is further metabolized to extracellular adenosine (a mechanism called the extracellular 2,3-cAMP-adenosine pathway). Adenosine-2'-monophosphate inhibits LPS-induced TNF-α and CXCL10 production via A2A receptor activation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2'-AMP; Adenosine 2'-phosphate; AMP 2'-phosphate. CAS No. 130-49-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-124151. | |
| Adenosine 2'-PEG-Biotin | Adenosine 2'-PEG-Biotin is a biochemical reagent derived from adenosine. Adenosine 2'-PEG-Biotin regulates cell signaling pathways by mimicking the effects of endogenous adenosine and binding to its receptors. Adenosine 2'-PEG-Biotin can be used in the research of bioprobes, biosensors and diagnostic reagents[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 362028-97-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-D2361. | |
| Adenosine 3',5'-diphosphate disodium | Adenosine 3',5'-diphosphate disodium is an endogenous purine nucleotide. Adenosine 3',5'-diphosphate disodium acts as an inhibitor of bovine adrenal estrogen sulfotransferase (EST) with a Ki value of 7.0 μM. It also serves as an indispensable specific cofactor for the pregnenolone-binding protein (PBP) steroid-binding complex, with an EC50 value of 1.5 μM in guinea pigs[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 75431-54-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-137243. | |
| Adenosine 5'-diphosphate | Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenosine diphosphate; ADP. CAS No. 58-64-0. Pack Sizes: 10 mM * 1 mL in Water; 100 mg. Product ID: HY-W010918. | |
| Adenosine 5'-diphosphate dicyclohexylammonium | Adenosine 5'-diphosphate dicyclohexylammonium is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate dicyclohexylammonium induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 102029-87-8. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-D0882. | |
| Adenosine 5'-diphosphate disodium | Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenosine diphosphate disodium; ADP disodium. CAS No. 16178-48-6. Pack Sizes: 5 g; 10 g. Product ID: HY-D0199. | |
| Adenosine 5-diphosphoribose | Adenosine 5-diphosphoribose (ADP ribose) is a nicotinamide adenine nucleotide (NAD+) metabolite. Adenosine 5-diphosphoribose is the most potent and primary intracellular Ca2+-permeable cation TRPM2 channel activator. Adenosine 5-diphosphoribose also can enhance autophagy[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ADP ribose. CAS No. 20762-30-5. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100973. | |
| Adenosine 5-diphosphoribose sodium | Adenosine 5-diphosphoribose sodium (ADP ribose sodium) is a nicotinamide adenine nucleotide (NAD+) metabolite. Adenosine 5-diphosphoribose sodium is the most potent and primary intracellular Ca2+-permeable cation TRPM2 channel activator. Adenosine 5-diphosphoribose sodium also can enhance autophagy[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ADP ribose sodium. CAS No. 68414-18-6. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100973A. | |
| Adenosine 5-diphosphoribose sodium (Standard) | Adenosine 5-diphosphoribose (sodium) (Standard) is the analytical standard of Adenosine 5-diphosphoribose (sodium). This product is intended for research and analytical applications. Adenosine 5-diphosphoribose sodium (ADP ribose sodium) is a nicotinamide adenine nucleotide (NAD+) metabolite. Adenosine 5-diphosphoribose sodium is the most potent and primary intracellular Ca2+-permeable cation TRPM2 channel activator. Adenosine 5-diphosphoribose sodium also can enhance autophagy[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ADP ribose sodium (Standard). CAS No. 68414-18-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100973AR. | |
| Adenosine 5'-monophosphate disodium | Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4578-31-8. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W011012. | |
| Adenosine 5'-monophosphate monohydrate | Adenosine 5'-monophosphate monohydrate is an adenosine A1 receptor agonist. Adenosine 5'-monophosphate monohydrate has significant antiviral activity against HSV-1 and HSV-2[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5'-AMP monohydrate. CAS No. 18422-05-4. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-A0181A. | |
| Adenosine 5-monophosphoramidate sodium | Adenosine 5-monophosphoramidate sodium is an adenosine derivative and can be used as an intermediate for nucleotide synthesis. Adenosine 5-monophosphoramidate has a significant effect on the accumulation of cyclic AMP[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 102029-68-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N7517. | |
| Adenosine 5'-triphosphate-13C10,15N5 ammonium solution (100 mM) | Adenosine 5'-triphosphate-13C10,15N5 (ammonium) is the 13C and 15N labeled Adenosine 5'-triphosphate ammonium[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2483830-25-5. Pack Sizes: 50 μL; 100 μL. Product ID: HY-150709S. | |
| Adenosine 5'-triphosphate(ATP)-d4 ammonium solution (100 mM) | Adenosine 5'-triphosphate(ATP)-d4 (ammonium salt) is the deuterium labeled Adenosine 5'-triphosphate(ATP) ammonium salt[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2483831-82-7. Pack Sizes: 20 μL; 100 μL; 200 μL. Product ID: HY-150770S. | |
| Adenosine-d1 | Adenosine-d is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenine riboside-d1; D-Adenosine-d. CAS No. 109923-50-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0228S. | |
| Adenosine-d2 | Adenosine-d2 is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenine riboside-d2; D-Adenosine-d2. CAS No. 82741-17-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-B0228S6. | |
| Adenosine deaminase, Calf Spleen | Adenosine deaminase, Calf Spleen is an enzyme that catalyzes the irreversible deamination of adenosine and 2'-deoxyadenosine to inosine and 2'-deoxyinosine, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RnADA, Calf Spleen. CAS No. 9026-93-1. Pack Sizes: 250 U. Product ID: HY-114175A. | |
| Adenosine deaminase, microorganism | Adenosine deaminase (RnADA) (EC 3.5.4.4) is an enzyme that catalyzes the irreversible deamination of adenosine and 2'-deoxyadenosine to inosine and 2'-deoxyinosine, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RnADA. CAS No. 9026-93-1. Pack Sizes: 250 U. Product ID: HY-114175. | |
| Adenosine dialdehyde | Adenosine dialdehyde, a purine nucleoside analogue, is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM)[1]. Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo and can be used for the cancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 34240-05-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-123055. | |
| Adenosine monophosphate | Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMP. CAS No. 61-19-8. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-A0181. | |
| Adenosine N1-oxide | Adenosine N1-oxide is an oral active anti-inflammatory agent, and can be isolated from royal jelly. Adenosine N1-oxide promotes osteogenic and adipocyte differentiation[1][2]. Uses: Scientific research. Category: Natural products. CAS No. 146-92-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-102082. | |
| Adenosyl-(3?5)-uridine sodium | Adenosyl-(3→5)-uridine (ApU) sodium is a nucleotide, which is composed of an adenine base and a uracil sugar molecule through a 3'-5' phosphodiester bond. Adenosyl-(3→5)-uridine (ApU) sodium participates in the biological processes, such as gene expression regulation, signal transduction, and protein synthesis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ApU sodium. CAS No. 43150-64-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164770A. | |
| Adenosylcobalamin | Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B12 which is a cofactor for methylmalonyl CoA mutase[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Coenzyme B12; Cobamamide; AdoCbl. CAS No. 13870-90-1. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-112790. | |
| Adenosylcobalamin (Standard) | Adenosylcobalamin (Standard) is the analytical standard of Adenosylcobalamin. This product is intended for research and analytical applications. Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B12 which is a cofactor for methylmalonyl CoA mutase[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Coenzyme B12 (Standard); Cobamamide (Standard); AdoCbl (Standard). CAS No. 13870-90-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112790R. | |
| Adenosylhomocysteinase | Adenosylhomocysteinase (SAHH; AHCY) is a highly conserved enzyme. Adenosylhomocysteinase reversible catalyzes S-adenosylhomocysteine (SAH) to adenosine and L-homocysteine. The serum exosomal Adenosylhomocysteinase level can be used as a prognostic biomarker in HBV-LC patients[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SAHH; AHCY. CAS No. 9025-54-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-149048. | |
| Adenylosuccinic acid | Adenylosuccinic acid (Adenylosuccinate; Aspartyl adenylate) is a purine ribonucleoside monophosphate and plays a role in nucleotide cycle metabolite. Adenylosuccinic acid can be converted into fumaric acid through adenylosuccinate lyase. Adenylosuccinic acid has the potential for the study of duchenne muscular dystrophy(DMD)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenylosuccinate; Aspartyl adenylate. CAS No. 19046-78-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-127137. | |
| Adenylyl cyclase type 2 agonist-1 | Adenylyl cyclase type 2 agonist-1 (Compound 73) is a potent agonist of adenylyl cyclase type 2 (AC2) with the EC50 of 90 nM. Adenylyl cyclase type 2 agonist-1 inhibits expression of Interleukin-6, making it a potential lead compound against respiratory diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2414908-52-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-146356. | |
| Aderamastat | Aderamastat (FP-025) is an orally active, selective MMP-12 inhibitor. Aderamastat provides protection against house dust mite (HDM)-sensitized allergic asthma. Aderamastat can be used in the research of respiratory diseases, including chronic inflammatory airway diseases and pulmonary fibrosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FP-025. CAS No. 877176-23-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156963. | |
| Aderbasib | Aderbasib (INCB007839) is a potent, orally active and target specific low nanomolar hydroxamate-based inhibitor of ADAM10 and ADAM17. Aderbasib exhibits robust antineoplastic activity and can be used for cancer research, including diffuse large B-cell non-Hodgkin lymphoma, HER2+ breast cancer, gliomas, et al[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: INCB007839; INCB7839. CAS No. 791828-58-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10293. | |
| Adezkibart | Adezkibart is a human monoclonal antibody immunosuppressant targeting the human FMS-like tyrosine kinase 3 ligand (FLT3LG). Adezkibart is found in the Chinese hamster ovary cell line CHO-K1, which binds to FLT3LG to block the relevant signaling pathway, inhibits the immune response, and exerts immunosuppressive activity. Adezkibart is promising for research of immune-related diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2921564-55-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991114. | |
| Adezmapimod | Adezmapimod (SB 203580) is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. Adezmapimod inhibits LCK, GSK3β and PKBα with IC50s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod can inhibit p38 MAPK and lead to the inhibition of downstream HSP27 phosphorylation. Adezmapimod does not disrupt JNK activity and is an autophagy and mitophagy activator[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SB 203580; RWJ 64809. CAS No. 152121-47-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10256. | |
| Adezmapimod hydrochloride | Adezmapimod (SB 203580; RWJ 64809) hydrochloride is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. Adezmapimod hydrochloride inhibits LCK, GSK3β and PKBα with IC50s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod hydrochloride does not disrupt JNK activity and is an autophagy and mitophagy activator[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SB 203580 hydrochloride; RWJ 64809 hydrochloride. CAS No. 869185-85-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-10256A. | |
| Adezmapimod hydrochloride (Standard) | Adezmapimod (hydrochloride) (Standard) is the analytical standard of Adezmapimod (hydrochloride). This product is intended for research and analytical applications. Adezmapimod (SB 203580; RWJ 64809) hydrochloride is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. Adezmapimod hydrochloride inhibits LCK, GSK3β and PKBα with IC50s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod hydrochloride does not disrupt JNK activity and is an autophagy and mitophagy activator[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SB 203580 hydrochloride (Standard); RWJ 64809 hydrochloride (Standard). CAS No. 869185-85-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10256AR. | |
| Adezmapimod (Standard) | Adezmapimod (Standard) is the analytical standard of Adezmapimod. This product is intended for research and analytical applications. Adezmapimod (SB 203580) is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. Adezmapimod inhibits LCK, GSK3β and PKBα with IC50s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod can inhibit p38 MAPK and lead to the inhibition of downstream HSP27 phosphorylation. Adezmapimod does not disrupt JNK activity and is an autophagy and mitophagy activator[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SB 203580 (Standard); RWJ 64809 (Standard). CAS No. 152121-47-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10256R. | |
| ADH-1 | ADH-1, an N-cadherin antagonist, inhibits N-cadherin mediated cell adhesion. Uses: Scientific research. Category: Signaling pathways. CAS No. 229971-81-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13541. | |
| ADH-1 trifluoroacetate | ADH-1 trifluoroacetate is an N-cadherin antagonist, which inhibits N-cadherin mediated cell adhesion. Uses: Scientific research. Category: Signaling pathways. CAS No. 1135237-88-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13541A. | |
| ADH-503 | ADH-503 ((Z)-Leukadherin-1 choline) is an orally active and allosteric CD11b agonist. ADH-503 leads to the repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhances dendritic cell responses[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (Z)-Leukadherin-1 choline. CAS No. 2055362-74-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15701B. | |
| Adhesamine | Adhesamine, dumbbell-shaped molecule, activates MAPK/FAK pathway. Adhesamine promotes adhesion and growth of mammalian cells. Adhesamine accelerates the differentiation and improves the survival of mice hippocampal neurons in primary culture[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 462605-73-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-122672. | |
| ADHP | ADHP is a fluorogenic peroxidase substrate (λex=530 nm, λem=590 nm). Uses: Scientific research. Category: Signaling pathways. Alternative Names: 10-Acetyl-3,7-dihydroxyphenoxazine. CAS No. 119171-73-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101880. | |
| Adibelivir | Adibelivir (IM-250) is an orally active helicase-primase inhibitor. Adibelivir is effective against HSV infection and reduces reactivation of latent HSV. Adibelivir inhibits HSV-1 infection in Vero cells (IC50: ~20 nM). Adibelivir can be used for the study of recurrent herpes disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IM-250. CAS No. 2305750-23-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150306. | |
| Adimanebart | ARGX-119 is a first-in-class humanized agonist monoclonal antibody specific for muscle-specific kinase (MuSK). ARGX-119 can be used for the study of neuromuscular diseases. The isotype control for ARGX-119 can refer to Human IgG1 lambda1, Isotype Control (HY-P99992)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ARGX-119. CAS No. 2966023-63-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P991066. | |
| Adintrevimab | Adintrevimab (ADG 20) is a human IgG1 monoclonal SARS-CoV (SARS-CoV) antibody. Adintrevimab inhibits SARS-CoV-2 variants and other SARS-like coronaviruses with pandemic potential[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ADG 20. CAS No. 2516243-54-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99423. | |
| Adipic acid-13C6 | Adipic acid-13C6 (Hexanedioic acid-13C6) is the 13C labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hexanedioic acid-13C6. CAS No. 942037-55-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W017522S1. | |
| AdipoRon | AdipoRon is an orally active adiponectin receptor (AdipoR) agonist, binding to AdipoR1 and AdipoR2 with Kds of 1.8 and 3.1 μM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 924416-43-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 1 g. Product ID: HY-15848. | |
| AdipoRon hydrochloride | AdipoRon hydrochloride is an orally active and specific AdipoR agonist, binding to AdipoR1 and AdipoR2, with Kds of 1.8 and 3.1 μM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1781835-20-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110164. | |
| ADL-5747 | ADL-5747 is a selective and orally active agonist of the δ-opioid receptor (DOR). By binding to the δ-opioid receptors, ADL-5747 activates these receptors, thereby playing a role in pain management pathways. ADL-5747 can be used for research into pain management mechanisms[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 850176-30-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-14157. | |
| ADL-5859 hydrochloride | ADL-5859 hydrochloride (compound 20) is a selective and orally active δ opioid receptor (DOR) agonist with an Ki and an EC50 value of 0.84 and 20 nM, respectively. ADL-5859 hydrochloride also shows inhibitory activity to hERG channel with an IC50 value of 78 μM. ADL-5859 hydrochloride can be used for the research of pain[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 850173-95-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13044. | |
| Adomeglivant | Adomeglivant (LY2409021) is a potent, selective glucagon receptor (GluR) allosteric antagonist. Adomeglivant is widely used in the research for type 2 diabetes mellitus[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY2409021. CAS No. 1488363-78-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19904. | |
| ADP-β-S trilithium | ADP-β-S (Adenosine 5'-(β-thiodiphosphate)) trilithium is a non-hydrolyzable ADP analog and a P2Y12 receptor agonist. ADP-β-S trilithium activates the P2Y12 receptor in microglia, thereby triggering downstream inflammatory signaling pathways. ADP-β-S trilithium activates P2Y purinergic receptors in rat pancreatic β cells and enhances glucose-induced insulin secretion. ADP-β-S trilithium can be used in the research of diseases such as inflammation and diabetes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenosine 5'-β-thiodiphosphate trilithium. CAS No. 73536-95-5. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg. Product ID: HY-134353B. | |
| Adrafinil | Adrafinil (CRL 40028) is an orally active vigilance promoting agent. Adrafinil enhances central noradrenergic transmission, improves spontaneous activity, exploratory behavior, discriminative learning ability and response motivation, but impairs visuospatial working memory. Adrafinil antagonizes Prazosin (HY-B0193)-induced hypoactivity and hypothermia, exerts anticonvulsant effects, and induces sustained enhancement of high-frequency electrocortical activity. Adrafinil can be used for research on decreased alertness and specific cognitive deficits[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CRL 40028. CAS No. 63547-13-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17549. | |
| Adrenochrome | Adrenochrome (Adraxone) is an oxidation product of Epinephrine. Adrenochrome is a potent coronary constricting agent in the rat heart. Adrenochrome can be used for neurological disorder research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adraxone. CAS No. 54-06-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116513. | |
| Adrenocorticotropic hormone | Adrenocorticotropic hormone (ACTH; Adrenocorticotrophic hormone) is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone stimulates cortisol secretion from the adrenal cortex via the hypothalamic-pituitary-adrenal (HPA) axis. Adrenocorticotropic hormone regulates cortisol and androgen production. Adrenocorticotropic hormone can promote the development of spermatogenesis. Adrenocorticotropic hormone can relieve acute inflammation in gout models by inhibiting the polarization of macrophages to M1 type, inhibiting ROS and proinflammatory factor production and protecting mitochondrial function. Adrenocorticotropic hormone can be used for the researches of inflammation, endocrinology, metabolic disease, such as gout and nephrotic syndrome[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACTH; Adrenocorticotrophic hormone. CAS No. 9002-60-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-106373. | |
| Adrenocorticotropic hormone (1-39), rat | Adrenocorticotropic hormone (1-39), rat is a potent melanocortin 2 (MC2) receptor agonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACTH(1-39), rat. CAS No. 77465-10-2. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1477. | |
| Adrenocorticotropic Hormone (ACTH) (1-39), human | Adrenocorticotropic Hormone (ACTH) (1-39), human is a melanocortin receptor agonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-39-Corticotropin (human). CAS No. 12279-41-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1211. | |
| Adrenomedullin (1-50), rat | Adrenomedullin (1-50), rat is a 50 amino acid peptide, which induces a selective arterial vasodilation via activation of CGRP1 receptor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adrenomedullin (rat). CAS No. 161383-47-7. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P1534. | |
| Adrenomedullin (AM) (13-52), human | Adrenomedullin (AM) (13-52), human is a 40 amino acid peptide, which acts as an endothelium-dependent vasodilator agent. Uses: Scientific research. Category: Peptides. CAS No. 154765-05-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1457. | |
| Adrenomedullin (AM) (1-52), human | Adrenomedullin (AM) (1-52), human is a 52-amino acid peptide, which affects cell proliferation and angiogenesis in cancer. Uses: Scientific research. Category: Peptides. Alternative Names: Human adrenomedullin-(1-52)-NH2. CAS No. 148498-78-6. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1455. | |
| Adrenomedullin (AM) (22-52), human | Adrenomedullin (AM) (22-52), human, an NH2 terminal truncated adrenomedullin analogue, is an adrenomedullin receptor antagonist, and also antagonizes the calcitonin generelated peptide (CGRP) receptor in the hindlimb vascular bed of the cat[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 22-52-Adrenomedullin (human). CAS No. 159899-65-7. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P1471. | |
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