MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| PYR-41 | PYR-41 is a selective and cell permeable inhibitor of ubiquitin-activating enzyme E1 with an IC50 of < 10 μM, with little activity at E2 and E3. Uses: Scientific research. Category: Signaling pathways. CAS No. 418805-02-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13296. |  |
| Pyr6 | Pyr6 is a selective store operated calcium entry (SOCE) inhibitor with an IC50 of 0.49 μM. Pyr6 displays 37-fold higher potency for RBL SOCE than for TRPC3 ROCE[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide. CAS No. 245747-08-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-12504. | |
| Pyraclostrobin | Pyraclostrobin is a highly effective and broad-spectrum strobilurin fungicide. Pyraclostrobin can induce oxidative DNA damage, mitochondrial dysfunction and autophagy through the activation of AMPK/mTOR signaling. Pyraclostrobin can be used to control crop diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 175013-18-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-N6626. | |
| Pyranine | Pyranine (HPTS; Solvent Green 7) is a cell-impermeant pH-sensitive fluorescent indicator. Pyranine acts as a class of fluorescent chemosensor for the Cu+ ion. Pyranine is used as a coloring agent, biological stain, optical detecting reagent, and pH indicator (Ex/Em = 450/510 nm)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HPTS; Solvent Green 7. CAS No. 6358-69-6. Pack Sizes: 500 mg; 1 g. Product ID: HY-D0023. | |
| Pyranose oxidase, Coriolus sp. | Pyranose oxidase, Coriolus sp. is an oxidoreductase targeting monosaccharides (e.g., D-glucose, D-galactose). Pyranose oxidase, Coriolus sp. is promising for research of biosensors (glucose, 1,5-anhydroglucitol detection) and biofuel cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 37250-80-9. Pack Sizes: 1 KU. Product ID: HY-P2889. | |
| Pyrantel pamoate | Pyrantel pamoate (Pyrantel embonate) is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel pamoate can cause spasmodic muscle paralysis in parasites. Pyrantel pamoate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyrantel embonate. CAS No. 22204-24-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-12640. | |
| Pyr-Arg-Thr-Lys-Arg-AMC TFA | Pyr-Arg-Thr-Lys-Arg-AMC TFA is a AMC peptide, and a fluorescent substrate. Pyr-Arg-Thr-Lys-Arg-AMC TFA can be used to detect the activity of specific proteases, such as Furin, Trypsin, and Thrombin[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1255501-99-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P4349A. | |
| Pyrazinamide | Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyrazinecarboxamide; Pyrazinoic acid amide. CAS No. 98-96-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 50 g; 100 g; 250 g; 500 g; 1 k g. Product ID: HY-B0271. | |
| Pyrazinamide-d3 | Pyrazinamide-d3 is deuterium labeled Pyrazinamide. Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyrazinecarboxamide-d3; Pyrazinoic acid amide-d3. CAS No. 1432059-16-9. Pack Sizes: 1 mg. Product ID: HY-B0271S. | |
| Pyrazine-2,3,5,6-tetracarboxylic acid | Pyrazine-2,3,5,6-tetracarboxylic acid (Pyrazinetetracarboxylic acid) is a metal-organic framework (MOF). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyrazinetetracarboxylic acid. CAS No. 43193-60-8. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W025580. | |
| Pyrazoloacridine | Pyrazoloacridine (NSC 366140), an intercalating agent with anti-cancer activity, inhibits the activity of topoisomerases 1 and 2. Pyrazoloacridine (NSC 366140) exhibits an IC50 of 1.25 μM in K562 myeloid leukemia cells for 24 h treatment[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 366140; PD 115934. CAS No. 99009-20-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108969. | |
| Pyrene 1,3,6,8-tetracarboxylic acid | Pyrene 1,3,6,8-tetracarboxylic acid is a metal-organic framework (MOF). Uses: Scientific research. Category: Signaling pathways. CAS No. 861023-19-0. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W112104. | |
| Pyrene maleimide | Pyrene maleimide is a polyaromatic fluorescent hydrocarbon with a termininal maleimide group. The maleimide group will react with a thiol group to form a covalent bond. Uses: Scientific research. Category: Signaling pathways. CAS No. 1869968-64-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-D1364. | |
| Pyrethrin II | Pyrethrin II is an orally active insecticidal ester of chrysanthemum acid found in Chrysanthemum cinerariifolium and C. coccineum Willd., an active constituent of pyrethrum extract with low mammalian toxicity. Pyrethrin II exhibits antiparasitic activity. Pyrethrin II can be used for the research of allergic contact dermatitis and parasitic infections[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 121-29-9. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-108170. | |
| Pyribencarb | Pyribencarb is a benzylcarbamate-type fungicide, which is active against a wide range of plant pathogenic fungi. Pyribencarb is a potent Qo inhibitor of cytochrome b. Pyribencarb is especially active against Botrytis cinerea and Sclerotinia sclerotirum[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 799247-52-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W020043. | |
| Pyridalyl | Pyridalyl (S 1812) is an insecticides against Lepidoptera and Thrips. Pyridalyl is less toxic to some beneficial arthropods, and non-target organisms, such as mammals and fish, and thus be utilized in integrated pest management and resistance management[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S 1812. CAS No. 179101-81-6. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-119779. | |
| Pyridine-3,5-dicarboxylic acid | Pyridine-3,5-dicarboxylic acid is a drug intermediate that can be used to construct new metal-organic framework materials[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 499-81-0. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 50 g; 100 g; 500 g; 1 k g. Product ID: HY-W002000. | |
| Pyridinium bisretinoid A2E TFA | Pyridinium bisretinoid A2E (A2E) TFA is a fluorophore that can be isolated from lipofuscin in the retinal pigment epithelium (RPE). Pyridinium bisretinoid A2E TFA is an initiator of blue-light-induced apoptosis. Photoactivation of Pyridinium bisretinoid A2E TFA mediates autophagy and the production of reactive oxygen species. Pyridinium bisretinoid A2E TFA can be used in the study of retinal degenerative diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: A2E TFA; N-retinylidene-N-retinylethanolamine TFA. CAS No. 1821308-73-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134928A. | |
| Pyridone 6 | Pyridone 6 is a pan-JAK inhibitor, which potently inhibits the JAK kinase family, with IC50s of 1 nM for JAK2 and TYK2, 5 nM for JAK3, and 15 nM for JAK1, while displaying significantly weaker affinities (130 nM to >10 mM) for other protein tyrosine kinases. Uses: Scientific research. Category: Signaling pathways. CAS No. 457081-03-7. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14435. | |
| Pyridostatin hydrochloride | Pyridostatin (RR82) hydrochloride is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin hydrochloride promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin hydrochloride targets the proto-oncogene Src. Pyridostatin hydrochloride reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RR82 hydrochloride. CAS No. 1781882-65-2. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15176A. | |
| Pyridostatin TFA | Pyridostatin (RR82) TFA is a G-quadruplex (G4) inducer/stabilizer with a Kd of 490 nM. Pyridostatin TFA also acts as an inhibitor of Zika virus (ZIKV) NS2B-NS3 protease, with an IC50 of 11.0 μM. Pyridostatin TFA interacts with G-quadruplex structures, regulates the expression of SRC and SUB1, and induces replication- and transcription-dependent DNA damage, growth arrest, and genomic instability. Pyridostatin TFA exhibits antiproliferative and antiviral activities. Pyridostatin TFA can be used in studies related to breast cancer, cervical cancer, and Zika virus infection[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RR82 TFA. CAS No. 1472611-44-1. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15176B. | |
| Pyridostigmine bromide | Pyridostigmine bromide is an orally active cholinesterase (ChE) inhibitor that can be used in cardiovascular disease research[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 101-26-8. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B0207A. | |
| Pyridoxal | Pyridoxal is a neuroprotectant. Pyridoxal is one of the main forms of vitamin B6. Pyridoxal is phosphorylated by pyridoxal kinase to pyridoxal phosphate (HY-B1744). Pyridoxal is oxidized by the liver to 4-pyridoxic acid (HY-113493) and excreted in the urine. Pyridoxal has shown promise in the study of carpal tunnel syndrome (CTS)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyridoxaldehyde. CAS No. 66-72-8. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-107469. | |
| Pyridoxal 5'-?phosphate monohydrate | Pyridoxal 5'-phosphate monohydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate monohydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5?phosphate (PNP) and pyridoxamine 5?phosphate (PMP)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyridoxal phosphate monohydrate. CAS No. 41468-25-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-W011727A. | |
| Pyridoxal isonicotinoyl hydrazone | Pyridoxal isonicotinoyl hydrazone is an orally active and lipophilic iron-specific chelator that acts as a non-competitive inhibitor of ferrochelatase (FECH) by binding iron ions. Pyridoxal isonicotinoyl hydrazone disrupts heme biosynthesis, leading to reduced FECH stability and increased protoporphyrin IX (PPIX) accumulation. Pyridoxal isonicotinoyl hydrazone is promising for research of iron-overload diseases (e.g., β-thalassemia)[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 737-86-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114758. | |
| Pyridoxal phosphate | Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyridoxal 5-phosphate; Pyridoxyl phosphate. CAS No. 54-47-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 1 g. Product ID: HY-B1744. | |
| Pyridoxal Phosphate-d3 | Pyridoxal Phosphate-d3 is the deuterium labeled Pyridoxal 5'-phosphate. Pyridoxal 5'-phosphate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5?phosphate (PNP) and pyridoxamine 5-phosphate (PMP)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyridoxal 5'-phosphate-d3. CAS No. 1354560-58-9. Pack Sizes: 500 μg; 1 mg. Product ID: HY-W011727S. | |
| Pyridoxal phosphate (Standard) | Pyridoxal phosphate (Standard) is the analytical standard of Pyridoxal phosphate. This product is intended for research and analytical applications. Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyridoxal 5-phosphate (Standard); Pyridoxyl phosphate (Standard). CAS No. 54-47-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1744R. | |
| Pyridoxal (Standard) | Pyridoxal (Standard) is the analytical standard of Pyridoxal. This product is intended for research and analytical applications. Pyridoxal is a neuroprotectant. Pyridoxal is one of the main forms of vitamin B6. Pyridoxal is phosphorylated by pyridoxal kinase to pyridoxal phosphate (HY-B1744). Pyridoxal is oxidized by the liver to 4-pyridoxic acid (HY-113493) and excreted in the urine. Pyridoxal has shown promise in the study of carpal tunnel syndrome (CTS)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyridoxaldehyde (Standard). CAS No. 66-72-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107469R. | |
| Pyridoxamine 5-phosphate | Pyridoxamine 5-phosphate is the active form of vitamin B6 bound to phosphoric acid. Pyridoxamine 5-phosphate is the aminated form of Pyridoxal 5'-?phosphate monohydrate (HY-W011727A) and as co-factor of a variety of enzymes central metabolite, potent antioxidant, vitamin B6 vitamer and enzyme substrate. Pyridoxamine 5-phosphate can be interconverted with pyridoxal 5'-phosphate hydrate[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 529-96-4. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg. Product ID: HY-B1746. | |
| Pyridoxamine-d3 dihydrochloride | Pyridoxamine-d3 (dihydrochloride) is the deuterium labeled Pyridoxamine dihydrochloride[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1173023-45-4. Pack Sizes: 500 μg; 1 mg. Product ID: HY-141923S. | |
| Pyridoxine | Pyridoxine (Pyridoxol) is one of the components of vitamin B6. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyridoxol. CAS No. 65-23-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-B1328. | |
| Pyridoxine-d2 hydrochloride | Pyridoxine-d2 (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride. Pyridoxine hydrochloride is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyridoxol-d2 hydrochloride; Vitamin B6-d2 hydrochloride. CAS No. 5027-82-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0682S1. | |
| Pyridoxine-d3 hydrochloride | Pyridoxine-d3 (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride. Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyridoxol-d3 hydrochloride; Vitamin B6-d3 hydrochloride. CAS No. 1189921-12-7. Pack Sizes: 500 μg; 1 mg. Product ID: HY-N0682S. | |
| Pyridoxine hydrochloride | Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitamin B6 hydrochloride. CAS No. 58-56-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-N0682. | |
| Pyridoxylamine | Pyridoxylamine is an advanced glycation end production (AGEs) and lipoxidation end products (ALEs) inhibitor, to protect against diabetes-induced retinal vascular lesions. Uses: Scientific research. Category: Signaling pathways. CAS No. 85-87-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-B1745. | |
| Pyrimethamine | Pyrimethamine (Pirimecidan) is a potent, orally active dihydrofolate reductase (DHFR) inhibitor. Pyrimethamine is an antimalarial agent. Pyrimethamine affects the nucleoprotein metabolism of malarial parasites by interference in the folic-folinic acid systems and affects cell division by inhibiting the conversion of dihydrofolate to tetrahydrofolate[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pirimecidan; Pirimetamin; RP 4753. CAS No. 58-14-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-18062. | |
| Pyrimethanil | Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops[1]. Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 53112-28-0. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B2033. | |
| Pyrintegrin | Pyrintegrin is an β1-integrin agonist and a 2,4-disubstituted pyrimidine that promotes embryonic stem cells survival. Pyrintegrin enhances cell-extracellular matrix (ECM) adhesion-mediated integrin signaling. Pyrintegrin can be used as a podocyte-protective agent and has robustly adipogenic[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1228445-38-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13306. | |
| Pyripyropene A | Pyripyropene A is an orally active, potent and selective sterol O-acyltransferase 2 (SOAT2)/acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) inhibitor, with an IC50 of 0.07 μM. Pyripyropene A attenuates hypercholesterolemia and atherosclerosis in vivo[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 147444-03-9. Pack Sizes: 250 μg; 500 μg. Product ID: HY-117832. | |
| Pyrithiamine hydrobromide | Pyrithiamine hydrobromide is a thiamine metabolic inhibitor that can act as a substrate for thiamine pyrophosphokinase. Pyrithiamine hydrobromide can be used in the research of nervous system diseases [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 534-64-5. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122273. | |
| Pyrithione | Pyrithione is an inhibitor of membrane transport processes in fungi. Pyrithione is a potent antibiotic aspergillic acid. Pyrithion incubated Penicillium mycelia would have a marked decrease in the activities of a variety of independently regulated transport systems[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1121-30-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1747. | |
| Pyrogallol (Standard) | Pyrogallol (Standard) is the analytical standard of Pyrogallol. This product is intended for research and analytical applications. Pyrogallol is a polyphenol compound, which has anti-fungal and anti-psoriatic properties. Pyrogallol is a reductant that is able to generate free radicals, in particular superoxide anions. Uses: Scientific research. Category: Signaling pathways. CAS No. 87-66-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1579R. | |
| Pyronaridine tetraphosphate | Pyronaridine tetraphosphate is an orally active Mannich base anti-malarial agent. Pyronaridine tetraphosphate is active against P. falciparum and Echinococcus granulosus infection[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 76748-86-2. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-14749A. | |
| Pyronin Y | Pyronin Y (Pyronine G) is a cationic dye that intercalates RNA and has been used to target cell structures including RNA, DNA and organelles. Pyronin Y forms fluorescent complexes with double-stranded nucleic acids (especially RNA) enabling semi-quantitative analysis of cellular RNA. Pyronin Y can be used to identify specific RNA subspecies of ribonuclear proteins complexes in live cells[1][2][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyronine G; C.I. 45005. CAS No. 92-32-0. Pack Sizes: 100 mg; 200 mg. Product ID: HY-D0971. | |
| Pyropheophorbide-a | Pyropheophorbide-a (Ppa) is a photosensitizer used in photodynamic therapy (PDT) for tumors. Pyropheophorbide-a exhibits phototoxic effects on tumor cells, such as cervical cancer cells, and also has anti-lipogenesis activity. Pyropheophorbide-a shows potential for research in the fields of cancer and age-related macular degeneration (AMD). Pyropheophorbide-a derivatives also demonstrate inhibitory activity against tumor cells[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 24533-72-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128973. | |
| Pyrotinib | Pyrotinib (SHR-1258) is a potent and selective EGFR/HER2 dual inhibitor with IC50s of 13 and 38 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SHR-1258. CAS No. 1269662-73-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-104065. | |
| Pyrotinib dimaleate | Pyrotinib dimaleate (SHR-1258 dimaleate) is a potent and selective EGFR/HER2 dual inhibitor with IC50s of 13 and 38 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SHR-1258 dimaleate. CAS No. 1397922-61-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104065B. | |
| Pyroxamide | Pyroxamide is a potent inhibitor of histone deacetylase 1 (HDAC1) with an ID50 of 100 nM. Pyroxamide can induce apoptosis and cell cycle arrest in leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 382180-17-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13216. | |
| Pyroxasulfone | Pyroxasulfone is a broad-spectrum pyrazole Herbicide. Pyroxasulfone is effective against a variety of annual grass weeds and some broadleaf weeds. Pyroxasulfone causes reduced plant height, decreased above-ground dry weight and yield loss in pinto beans and red Mexican beans[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 447399-55-5. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-136633. | |
| Pyrrolidinedithiocarbamate ammonium | Pyrrolidinedithiocarbamate ammonium (Ammonium pyrrolidinedithiocarbamate) is a selective and blood-brain barrier (BBB) permeable NF-κB inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ammonium pyrrolidinedithiocarbamate; PDTC ammonium; APDC. CAS No. 5108-96-3. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-18738. | |
| Pyrroline-5-carboxylate sodium | Pyrroline-5-carboxylate sodium is a key intermediate in proline anabolism and catabolism. Pyrroline-5-carboxylate sodium plays important roles in plant defense against pathogen invasion, as well as in redox regulation, nucleotide synthesis and other processes in animal cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 72978-16-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138354A. | |
| Pyrrolnitrin | Pyrrolnitrin is an antibiotic isolated from Pseudomonas pyrrocinia. Pyrrolnitrin shows a broad spectrum of antibiotic activity against fungi, yeast and gram-positive bacteria[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1018-71-9. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-133704. | |
| Pyrroloquinoline quinone | Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PQQ; Methoxatin. CAS No. 72909-34-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-100196. | |
| Pyrroloquinoline quinone disodium salt | Pyrroloquinoline quinone disodium salt, a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone disodium salt is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone disodium salt is an essential nutrient for mammals and is important for immune function[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PQQ disodium salt; Methoxatin disodium salt. CAS No. 122628-50-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100196A. | |
| Pyrroloquinoline quinone (Standard) | Pyrroloquinoline quinone (Standard) is the analytical standard of Pyrroloquinoline quinone. This product is intended for research and analytical applications. Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PQQ (Standard); Methoxatin (Standard). CAS No. 72909-34-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100196R. | |
| Pyrromethene 650 | Pyrromethene 650 (PM650) is a green-fluorescent polar tracer dye. It is used for investigations of membrane fusion, lysis, and gap-junctional communication and to detect volume changes in cells or liposomes. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PM650. CAS No. 157410-23-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W248583. | |
| Pyrrophenone | Pyrrophenone is a potent and specific cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 value of 4.2 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 341973-06-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-111376. | |
| Pyrrothiogatain | Pyrrothiogatain is a transcription factor GATA3 inhibitor with an IC50 of 54.7 μM. Pyrrothiogatain inhibits the DNA-binding activity of GATA3 and inhibits the T helper 2 (Th2) cell differentiation and expression of Th2 cytokines. Pyrrothiogatain shows anti-infection effect by inhibiting ACE2 expression. Pyrrothiogatain can be used for the researches of inflammation, immunology, infection and cancer, such as colon cancer and SARS-CoV-2 infection[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 477888-48-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138113. | |
| Pyruvate Carboxylase-IN-1 | Pyruvate Carboxylase-IN-1 (compound 37) is a potent pyruvate carboxylase inhibitor with antiproliferative activity. The IC50 values ??of pyruvate carboxylase-IN-1 against PC in cell lysates and cells are 0.204 and 0.104 μM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 70205-50-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-142684. | |
| Pyruvate Carboxylase-IN-5 | Pyruvate Carboxylase-IN-5 (compound 6m) is a pyruvate carboxylase inhibitor with high selectivity and permeability. Pyruvate carboxylase is a mitochondrial enzyme that catalyzes the carboxylation of pyruvate to oxaloacetate, a process that plays an important role in maintaining steady-state levels of Krebs cycle intermediates, which are precursors for the synthesis of biomacromolecules such as amino acids, fatty acids, and glucose[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3047101-14-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163771. | |
| Pyruvate decarboxylase | Pyruvate decarboxylase (PDC) is an enzyme that catalyses the decarboxylation of pyruvic acid to acetaldehyde. Pyruvate decarboxylase catalyses the non-oxidative conversion of pyruvate (or other 2-oxo acids) to acetaldehyde and CO2[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PDC. CAS No. 9001-4-1. Pack Sizes: 20 U; 100 U. Product ID: HY-P2796. | |
| Pyruvate Oxidase, Microorganisms | Pyruvate Oxidase, Microorganisms (PoxB) is a peripheral membrane enzyme, isolated from microorganisms. Pyruvate oxidase catalyzes the oxidative decarboxylation of pyruvate to acetyl phosphate, carbon dioxide and water. Pyruvate oxidase is an important enzyme in bacterial metabolism and is often used in biochemical research[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PoxB. CAS No. 9001-96-1. Pack Sizes: 100 U. Product ID: HY-P2891. | |
| Pyruvic acid | Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acetylformic acid. CAS No. 127-17-3. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 5 g; 10 g; 25 g; 50 g. Product ID: HY-Y0781. | |
| Pyruvic acid-13C3 sodium | Sodium 2-oxopropanoate-13C3 is the 13C-labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sodium 2-oxopropanoate-13C3; Acetylformic acid-13C3 sodium. CAS No. 142014-11-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W015913S. | |
| Pyruvic acid sodium | Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sodium 2-oxopropanoate; Acetylformic acid sodium. CAS No. 113-24-6. Pack Sizes: 10 mM * 1 mL in Water; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W015913. | |
| Pyruvic aldehyde (40%w/w in water) | Pyruvic aldehyde (40%w/w in water) is a cell stabilizer. Pyruvic aldehyde (40%w/w in water) can be used for stabilization of cells, such as erythrocytes. Pyruvic aldehyde (40%w/w in water) can be efficiently catalyzed to Lactic acid (HY-B2227) by a Lewis acid catalyst[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 78-98-8. Pack Sizes: 1 mL; 5 mL. Product ID: HY-W020014. | |
| Pyrvinium pamoate | Pyrvinium pamoate is an FDA-approved antihelmintic agent that inhibits WNT pathway signaling. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyrvinium embonate. CAS No. 3546-41-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0293. | |
| PYZD-4409 | PYZD-4409 is a specific inhibitor of the ubiquitin-activating enzyme UBA1 with an IC50 of 20 μM (cell-free enzymatic assay). PYZD-4409 induces cell death in malignant cells and preferentially inhibits the clonogenic growth of primary acute myeloid leukemia cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 423148-78-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13297. | |
| PZ-128 | PZ-128 (P1pal-7), a cell-penetrating lipopeptide pepducin, is a first-in-class, specific and reversible protease-activated receptor-1 (PAR1) antagonist. PZ-128 targets the cytoplasmic surface of PAR1 and interrupts signaling to internally-located G (PAR1-G) proteins. PZ-128 has antiplatelet, anti-metastatic, anti-angiogenic and anticancer effects[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: P1pal-7. CAS No. 371131-16-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107146. | |
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