MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| RB-3 | RB-3, a polycomb repressive complex 1 (PRC1) inhibitor, binds to RING1B-BMI1f, with a Kd of 2.8 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2396639-11-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139514. |  |
| (R)-Baclofen | (R)-Baclofen (Arbaclofen) is a selective GABAB receptor agonist[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Arbaclofen; STX209. CAS No. 69308-37-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-17354. | |
| (R)-b-Aminoisobutyric acid | (R)-β-Aminoisobutyric acid is a β-amino acid. (R)-β-Aminoisobutyric acid boosts myeloperoxidase microbicidal activity against susceptible microorganisms. (R)-β-Aminoisobutyric acid can be used for the research of bacterial infections[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2140-95-6. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W023331. | |
| (R)-BAY-85-8501 | (R)-BAY-85-8501 is the less active Enantiomer of BAY-85-8501. BAY-85-8501 is a selective and potent inhibitor of Human Neutrophil Elastase (HNE), with an IC50 of 65 pM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2446175-39-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19908B. | |
| (R)-(+)-Bay-K-8644 | (R)-(+)-Bay-K-8644 is a calcium channel inhibitor. (R)-(+)-Bay-K-8644 inhibits Ba2+ currents (IBa) (IC50=975 nM). Uses: Scientific research. Category: Signaling pathways. CAS No. 98791-67-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15125. | |
| RBC8 | RBC8 is a selective and allosteric RALA and RALB inhibitor. RBC8 stabilizes the inactive GDP-bound state of Ral, preventing its activation. RBC8 promotes the phosphorylation of proteins related to the MAPK/JNK pathway. RBC8 has the activity of inhibiting tumor cell proliferation, migration and invasion. RBC8 is used in the study of various cancers such as lung cancer, gastric cancer, and multiple myeloma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 361185-42-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12873. | |
| (R)-Benpyrine | (R)-Benpyrine is the isomer of Benpyrine (HY-133807), and can be used as an experimental control. Benpyrine is a highly specific and orally active TNF-α inhibitor with a KD value of 82.1 μM. Benpyrine tightly binds to TNF-α and blocks its interaction with TNFR1, with an IC50 value of 0.109 μM. Benpyrine has the potential for TNF-α mediated inflammatory and autoimmune disease research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2637243-08-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133807B. | |
| Rbin-2 | Rbin-2 is a potent, reversible and selective inhibitor of Midasin (Mdn1), an enzyme belonging to the AAA+ (ATPases associated with diverse cellular activities) protein family. Rbin-2 inhibits eukaryotic ribosome biogenesis and is a powerful probe for the eukaryotic ribosome assembly[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2032282-97-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100817. | |
| RBN012759 | RBN012759 is a potent, selective and orally active inhibitor of PARP14, with an IC50 of <3 nM. RBN012759 displays 300-fold selectivity over the monoPARPs and 1000-fold selectivity over the polyPARPs. RBN012759 decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2360851-29-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136979. | |
| RBN012811 | RBN012811 is a highly selective PROTAC-based PARP14 degrader. RBN012811 forms a ternary complex with cereblon by binding to the NAD+ site of PARP14, and mediates the specific degradation of PARP14 via the ubiquitin-proteasome pathway (IC50=10 nM). RBN012811 effectively depletes endogenous PARP14 in various cell lines and primary human macrophages, thereby downregulating IL-10 production and IFN-β mRNA levels, increasing phosphorylated STAT1 levels to enhance inflammatory signaling, and inhibiting interferon-induced ADPr condensate formation. RBN012811 also modulates viral replication, exhibiting increased HSV1 replication while reducing VSV replication. RBN012811 has important application value in research related to cancer and viral infections[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2569517-30-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-173679. | |
| RBN-2397 | RBN-2397 is a potent, accross species and orally active NAD+ competitive inhibitor of PARP7 (IC50<3 nM). RBN-2397 selectively binds to PARP7 (Kd=0.001 μM) and restores IFN signaling. RBN-2397 has the potential for the study of advanced or metastatic solid tumors[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2381037-82-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136174. | |
| RBN-3143 | RBN-3143 is a potent and NAD+-competitive catalytic PARP14 inhibitor with an IC50 value of 4 nM. RBN-3143 inhibits PARP14-mediated ADP-ribosylation and stabilizes PARP14 in cell lines. RBN-3143 can be used in research of lung inflammation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2360853-16-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150207. | |
| RBP4 inhibitor 1 | RBP4 inhibitor 1 (compound 43b) is a potent and orally active retinol-binding protein 4 (RBP4) inhibitor with IC50s of 28 nM and 110 nM for human and mouse RBP4. RBP4 inhibitor 1 has a potent and long-lasting blood RBP4-level-reducing effect in mice[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1198180-03-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143793. | |
| RBPJ Inhibitor-1 | RBPJ Inhibitor-1 (RIN1), the first RBPJ inhibitor, blocks the functional interaction of RBPJ with SHARP. RBPJ Inhibitor-1 (RIN1) inhibits NOTCH-dependent tumor cell proliferation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RIN1. CAS No. 2682114-39-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137471. | |
| (R)-BPO-27 | (R)-BPO-27, the R enantiomer of BPO-27, is a potent, orally active and ATP-competitive CFTR inhibitor with an IC50 of 4 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1415390-47-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19778. | |
| RC-3095 TFA | RC-3095 TFA is a selective bombesin/gastrin releasing peptide receptor (GRPR) antagonist[1]. RC-3095 TFA exerts protective effects by reducing gastric oxidative injury in the arthritic mice[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1217463-61-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0107A. | |
| (R)-Capivasertib | (R)-Capivasertib ((R)-AZD5363) is the R-enantiomer of Capivasertib (HY-15431)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-AZD5363. CAS No. 1143532-51-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15431A. | |
| (R)-Carvedilol | (R)-Carvedilol ((R)-BM 14190) is the orally active R-isomer of Carvedilol (HY-B0006). (R)-Carvedilol has α-receptor blocking activity but no β-receptor blocking activity. (R)-Carvedilol inhibits spontaneous Ca2+ waves. (R)-Carvedilol inhibits stress-induced ventricular tachycardia and delays the development of UV-induced skin tumors and reduces their malignancy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-BM 14190. CAS No. 95093-99-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0006C. | |
| RCB16007 | RCB16007 is a Yellow Fever Virus (YFV) Inhibitor. RCB16007 inhibits the West Nile virus (EC50: 7.9 μM, CC50: 17 μM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2952530-26-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157023. | |
| (R)-CDK2 degrader 6 | (R)-CDK2 degrader 6 is the R-enantiomer of CDK2 degrader 6 (HY-176444), a cereblon-based molecular glue degrader of CDK2 with a DC50 of 27 nM. (R)-CDK2 degrader 6 induces ubiquitination and proteasomal degradation of CDK2 by bridging cereblon and CDK2. (R)-CDK2 degrader 6 is applicable for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3083777-50-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-176444A. | |
| (R)-CE3F4 | (R)-CE3F4 is a potent and selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1), with an IC50 of 4.2 μM, with 10-fold selectivity for Epac1 over Epac2 (IC50, 44 μM). (R)-CE3F4 is more potent than racemic CE3F4 and (S)-CE3F4[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1593478-56-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108539A. | |
| (R)-cGAS-IN-4 | (R)-cGAS-IN-4 (Compound 77A*) is the R-enantiomer of cGAS-IN-4 (HY-170362). cGAS-IN-4 is an orally active inhibitor for cyclic GMP-AMP synthase (cGAS)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2987886-48-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-170362A. | |
| RCM-1 | RCM-1 is a forkhead box M1 (FOXM1) inhibitor with an EC50 of 0.72 μM in U2OS cells. RCM-1 blocks the nuclear localization and increased the proteasomal degradation of FOXM1. RCM-1 can be used for asthma and other chronic airway diseases research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 339163-65-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19979. | |
| (R)-CPP | (R)-CPP is a highly potent NMDA receptor antagonist[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 126453-07-4. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-100814. | |
| (R)?-?CR8 | (R)-CR8, a second-generation analog of Roscovitine, is a potent CDK1/2/5/7/9 inhibitor. (R)-CR8 inhibits CDK1/cyclin B (IC50=0.09 μM), CDK2/cyclin A (0.072 μM), CDK2/cyclin E (0.041 μM), CDK5/p25 (0.11 μM), CDK7/cyclin H (1.1 μM), CDK9/cyclin T (0.18 μM) and CK1δ/ε (0.4 μM). (R)-CR8 induces apoptosis and has neuroprotective effect[1][2]. (R)-CR8 acts as a molecular glue degrader that depletes cyclin K[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CR8, (R)-Isomer. CAS No. 294646-77-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18340. | |
| (R)-CR8 trihydrochloride | (R)-CR8 (CR8) trihydrochloride, a second-generation analog of Roscovitine, is a potent CDK1/2/5/7/9 inhibitor. (R)-CR8 trihydrochloride inhibits CDK1/cyclin B (IC50=0.09 μM), CDK2/cyclin A (0.072 μM), CDK2/cyclin E (0.041 μM), CDK5/p25 (0.11 μM), CDK7/cyclin H (1.1 μM), CDK9/cyclin T (0.18 μM) and CK1δ/ε (0.4 μM). (R)-CR8 trihydrochloride induces apoptosis and has neuroprotective effect[1][2]. (R)-CR8 trihydrochloride acts as a molecular glue degrader that depletes cyclin K[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CR8, (R)-Isomer trihydrochloride. CAS No. 1786438-30-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18340A. | |
| RD0392 | RD0392 (Compound 5) is a competitive tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitor (IC50=1.3 nM). RD0392 is promising for research of neurodegenerative diseases like Alzheimers[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1287651-83-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-176723. | |
| (R)-DOI hydrochloride | (R)-DOI hydrochloride is a selective 5HT2A receptor agonist. (R)-DOI hydrochloride has anti-inflammatory, anti-oxidative stress, and lysosomal function-improving effects. (R)-DOI hydrochloride can be used for the researches of inflammation and neurological disease, such as Alzheimer's disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 82864-02-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137572. | |
| Real Thiol | Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 2280796-90-7. Pack Sizes: 1 mg. Product ID: HY-108715. | |
| ReAsH-EDT2 | ReAsH-EDT2 is a red fluorescent dye that marks proteins. ReAsH-EDT2 is a membrane-permeable biarsenical compound that binds covalently to tetracysteine sequences which allows the protein to be imaged. ReAsH-EDT2 can be used for protein localization and trafficking. (λex=530 nm, λem=592 nm)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 438226-89-2. Pack Sizes: 100 μg; 250 μg. Product ID: HY-130533. | |
| Rebamipide | Rebamipide (OPC12759) is an orally active gastroprotective agent that enhances the production of endogenous PGs (especially intragastric PGE2) by inducing COX-2 expression, thereby protecting the gastric mucosa from injury. Rebamipide exerts anti-proliferative activity against gastric cancer cells. Rebamipide can be used in studies of mucosal protection, gastroduodenal ulcer, gastritis and gastric cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OPC12759; Proamipide. CAS No. 90098-04-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B0360. | |
| Rebamipide impurity 1 | Rebamipide impurity 1 is an impurity of Rebamipide (HY-B0360). Uses: Scientific research. Category: Signaling pathways. CAS No. 90098-05-8. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-Z0629. | |
| Rebastinib | Rebastinib (DCC-2036) is an orally active, non-ATP-competitive Bcr-Abl inhibitor for Abl1WT and Abl1T315I with IC50s of 0.8 nM and 4 nM, respectively. Rebastinib also inhibits SRC, KDR, FLT3, and Tie-2, and has low activity to seen towards c-Kit. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DCC-2036. CAS No. 1020172-07-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13024. | |
| Rebaudioside B | Rebaudioside B is the minor constituent isolated from the leaves of Stevia rebaudiana Bertoni. Rebaudioside B tastes about 150 times sweeter than sucrose. Rebaudioside B can hydrolysis to steviol[1][2]. Uses: Scientific research. Category: Natural products. CAS No. 58543-17-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N6808. | |
| Rebaudioside C | Rebaudioside C (Dulcoside B) is an orally effective natural sweetener that cannot pass the blood-brain barrier and selectively binds to human sweet taste receptors (TAS1R2/TAS1R3). The sweetness of Rebaudioside C is about 20-30 times that of sucrose, and its sweetness activity depends on the C-16/C-17 double bond structure and specific aglycones. The glycoside structure in the Rebaudioside C molecule can bind to the sweet taste receptor, activate the taste signal transduction pathway, and produce sweetness perception[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dulcoside B. CAS No. 63550-99-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0467. | |
| Rebaudioside D | Rebaudioside D is an orally active sweetener that targets and activates FXR, modulates Acetyl-CoA Carboxylase, and inhibits 3-hydroxy-3-methylglutaryl-CoA reductase. Rebaudioside D regulates bile acid homeostasis and lipid metabolism, reduces the synthesis rates of fatty acids and cholesterol, and exerts multiple effects including anti-adipogenesis, hepatoprotection, anti-steatosis, gut microbiota modulation, enhancement of secondary bile acid metabolism, anti-endotoxin activity, regulation of bile acid transport, and inhibition of bile acid efflux. Rebaudioside D also reduces body weight gain, visceral fat accumulation, hepatic triglyceride and cholesterol accumulation, hepatic lipid peroxidation, and decreases the circulating level of lipopolysaccharide-binding protein. Rebaudioside D additionally enhances the secondary bile acid metabolic pathway of intestinal bacteria, upregulates the gene expression of ileal organic solute transporter α, and downregulates the gene expression of hepatic bile salt export pump. Rebaudioside D does not affect glucose homeostasis, alter total caloric intake or fecal energy excretion, induce weight gain, exacerbate obesity, promote hepatic steatosis, impair brown adipose tissue function, nor change skeletal muscle metabolism-related proteins. Rebaudioside D can be used in diet-induced obesity and obesity-related research[1][2]. Uses: Scientific research. Category: Signaling pathways. | |
| Rebaudioside M | Rebaudioside M, a glycoside of the ent-kaurene diterpenoid aglycone, is a non-calorie sweetener isolated from Stevia rebaudiana. Rebaudioside M has antidiabetics, antihypertension, anti-inflammatory, antioxidant, anticaries and anticancer benefits. Rebaudioside M is more than 350 times sweeter than sucrose. Rebaudioside M can be used in food and beverage [1][2][3][4][5][6]. Uses: Scientific research. Category: Natural products. CAS No. 1220616-44-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6833. | |
| Reboxetine mesylate | Reboxetine mesylate (FCE20124 mesylate) is a potent, selective, and specific noradrenaline reuptake inhibitor (NARI) for the research of depression. Reboxetine mesylate inhibits the uptake of norepinephrine, with a Ki of 8 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FCE20124 mesylate; PNU155950E mesylate. CAS No. 98769-84-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14560C. | |
| Recoflavone | Recoflavone (DA-6034 (free acid)), a synthetic derivative of the flavonoid Eupatilin (HY-N0783), is orally active. Recoflavone can inhibit the NF-κB pathway and induce [Ca(2+)]i increase in epithelial cells. Recoflavone exhibits activities such as anti-inflammation, anti-tumor effects, protection of gastric and intestinal mucosa, and promotion of secretion in the ocular surface and salivary glands. Recoflavone can be used for the research of diseases such as dry eye, gastric injury, and intestinal injury[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DA-6034 free acid. CAS No. 203191-10-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106449. | |
| Recombinant DNase I (RNase-free) | Recombinant DNase I (RNase-free) is a recombinant deoxyribonuclease that degrades DNA. Recombinant DNase I is essential for limiting inflammatory responses and maintaining homeostasis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9003-98-9. Pack Sizes: 200 U; 500 U; 1 KU. Product ID: HY-108882A. | |
| Recombinant enterokinase | Recombinant enterokinase (rEK) is a serine protease and functions as the physiological activator of trypsinogen. Recombinant enterokinase plays a role of turning trypsinogen to its active form trypsin[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: rEK. CAS No. 9014-74-8. Pack Sizes: 100 U. Product ID: HY-E70202. | |
| Recombinant Kex2 protease | Recombinant Kex2 protease is a membrane-bound, Ca2+-dependent serine protease. Recombinant Kex2 protease specifically recognize and cleave the carboxyl-terminal peptide bonds of dibasic amino acids[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 99676-46-7. Pack Sizes: 1 mg. Product ID: HY-E70200. | |
| Recombinant myokinase, Rabbit muscle | Recombinant myokinase, Rabbit muscle (Myokinase), is a phosphotransferase enzyme, is often used in biochemical studies. Recombinant myokinase, Rabbit muscle catalyzes the interconversion of adenosine phosphates. Recombinant myokinase, Rabbit muscle monitors phosphate nucleotide levels inside the cell, it plays an important role in cellular energy homeostasis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Myokinase; Adk. CAS No. 9013-2-9. Pack Sizes: 1 KU. Product ID: HY-P2952. | |
| Recombinant Proteinase K (DNase & RNase free, animal free) | Recombinant Proteinase K (Protease K) (DNase & RNase free, animal free) is a nonspecific serine protease that is useful for general digestion of proteins. Proteinase K (DNase & RNase free, animal free) is active in the presence of SDS or urea and over a wide range of pH (4-12), salt concentrations, and temperatures. Proteinase K (DNase & RNase free, animal free) can be use for promoting methods of viral nucleic acid extraction, and detection. This product is of molecular biology grade, free of animal-derived ingredients, and is recombinantly purified from yeast[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Recombinant Protease K (DNase & RNase free, animal free). CAS No. 39450-01-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-108717A. | |
| Recombinant Trypsin Solution | Recombinant Trypsin Solution is an animal-free trypsin solution used to digest cells or tissues. Recombinant Trypsin Solution has high stability at room temperature and gentle digestion, and can be used to digest weakly adherent cells or stem cells under low serum or serum-free culture conditions. Compared with traditional trypsin digestion solution, Recombinant Trypsin Solution does not contain any animal-derived ingredients, is gentle and effective, and can replace the application of animal-derived trypsin in cell digestion[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9002-7-7. Pack Sizes: 20 mL; 100 mL. Product ID: HY-129047B. | |
| RECQL5-IN-1 | RECQL5-IN-1 (Compound 4a) acts as an orally effective RECQL5 inhibitor (targeting both enzymatic and nonenzymatic domain). RECQL5-IN-1 is a potent inhibitor of RECQL5 helicase activity (IC50=46.3 nM), stabilizes the interaction between RECQL5-RAD51 proteins, causes RAD51 aggregation and homologous recombination repair (HRR) inhibition, thereby exhibiting selective cytotoxicity in RECQL5-expressing cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2718170-45-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145685. | |
| Redafamdastat | Redafamdastat (PF-04457845), a chemical probe, is a highly efficacious and selective FAAH inhibitor with IC50 values is 7.2±0.63 nM and 7.4±0.62 nM for hFAAH and rFAAH, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-04457845. CAS No. 1020315-31-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14376. | |
| Redaporfin | Redaporfin (LUZ11) acts as a potent photosensitizer. Redaporfin causes direct antineoplastic effects as well as indirect immune-dependent destruction of malignant lesions[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LUZ11; F2BMet. CAS No. 1224104-08-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-17644. | |
| (R)-Edelfosine | (R)-Edelfosine ((R)-ET-18-OCH3) is a ether lipid analog with anti-HIV and antineoplastic activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-ET-18-OCH3. CAS No. 77286-66-9. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg. Product ID: HY-108610. | |
| Refametinib | Refametinib (BAY 869766; RDEA119) is an orally available, potent, non-ATP-competitive, selective, allosteric MEK1/MEK2 inhibitor with IC50s of 19 nM and 47 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY 869766; RDEA119. CAS No. 923032-37-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14691. | |
| Refanezumab | Refanezumab (GSK249320) is a brain-penetrant IgG1-type humanized monoclonal antibody directed against myelin-associated glycoprotein (MAG). Refanezumab binds to MAG and blocks MAG-mediated inhibition of axonal regeneration. Refanezumab has the potential for the enhancement of recovery of function poststroke[1][2]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: GSK249320. CAS No. 1233953-61-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99403. | |
| Regadenoson | Regadenoson (CVT-3146) is a selective A2A adenosine receptor agonist and vasodilator that increases coronary blood flow, can be used in study of myocardial perfusion imaging. Regadenoson also increases the permeability of the blood-brain barrier (BBB) in rodents, can be used to study increased delivery of agents to the human CNS[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CVT-3146. CAS No. 313348-27-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0168. | |
| Regorafenib | Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Regorafenib shows very robust antitumor and antiangiogenic activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY 73-4506. CAS No. 755037-03-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10331. | |
| Regorafenib Hydrochloride | Regorafenib Hydrochloride (BAY 73-4506 hydrochloride) is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY 73-4506 hydrochloride. CAS No. 835621-07-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13308. | |
| Regorafénib N-oxyde (M2) | Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 835621-11-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-I0678. | |
| Regrelor disodium | Regrelor disodium (INS 50589) is a platelet P2Y12 receptor antagonist. Regrelor disodium is a well-tolerated, reversible ADP competitive antagonist. Regrelor disodium inhibits cell proliferation. Regrelor disodium can be used in inflammation-related research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: INS50589. CAS No. 676251-22-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-123490. | |
| Rehmannic acid | Rehmannic acid (lantadene A) is a compound isolated from Lantana camara. Rehmannic acid shows considerable in vitro antioxidant, free radical scavenging capacity activities in a dose dependant manner. Rehmannic acid is a promising candidate for use as an antioxidant and hepatoprotective agent[1][2]. Uses: Scientific research. Category: Natural products. Alternative Names: Lantadene A. CAS No. 467-81-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1521. | |
| Relacatib | Relacatib (SB-462795) is a novel, potent, and orally active inhibitor of human cathepsins K, L, and V with Ki values of 41 pM, 68 pM, and 53 pM, respectively. Relacatib inhibits endogenous cathepsin K in situ in human osteoclasts and human osteoclast-mediated bone resorption with IC50 values of 45 nM and 70 nM, respectively. Relacatib inhibits bone resorption in vitro in human tissue as well as in cynomolgus monkeys in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SB-462795. CAS No. 362505-84-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-10294. | |
| Relamorelin TFA | Relamorelin (RM-131) TFA, a pentapeptide ghrelin analog, is a selective ghrelin/growth hormone secretagogue receptor (GHSR) agonist with a Ki of 0.42 nM for GHS-1a receptor. Relamorelin TFA is centrally penetrant. Relamorelin TFA increases growth hormone levels and accelerates gastric emptying. Relamorelin TFA has the potential for cachexia, gastroparesis, and gastric/intestinal dysmobility disorders research[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RM-131 TFA; BIM-28131 TFA. CAS No. 2863659-22-5. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19884B. | |
| Relatlimab | Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC50 value of 0.67 nM and LAG-3/FGL1 interaction with an IC50 value of 0.019 nM. Relatlimab can be used in research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-986016. CAS No. 1673516-98-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99156. | |
| (rel)-β-Tocopherol | (rel)-β-Tocopherol is a relative configuration of β-Tocopherol. β-Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 148-03-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113068. | |
| Reldesemtiv | Reldesemtiv (CK-2127107) is a selective, orally active and next-generation fast skeletal muscle troponin activator (FSTA). Reldesemtiv selectively activates fast skeletal myofibrils with an EC50 of 3.4 μM. Reldesemtiv increases exercise performance in a heart failure model[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CK-2127107. CAS No. 1345410-31-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109121. | |
| Relebactam | Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases and KPC) and class C (AmpC) enzymes. Relebactam shows antibacterial activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-7655. CAS No. 1174018-99-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16752. | |
| Relebactam (Standard) | Relebactam (Standard) is the analytical standard of Relebactam. This product is intended for research and analytical applications. Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases and KPC) and class C (AmpC) enzymes. Relebactam shows antibacterial activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-7655 (Standard). CAS No. 1174018-99-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16752R. | |
| (rel)-ML-SI3 | (rel)-ML-SI3 is one of the active ingredients of ML-SI3 (HY-139426) (another component is (cis)-ML-SI3) that targets three isoforms of TRPML. (rel)-ML-SI3 is an inhibitor of TRPML1 and TRPML3 (IC50=3.1 μM/28.5 μM), and a potent activator of TRPML2 (EC50=3.3 μM)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: trans-ML-SI3. CAS No. 2108567-79-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139426A. | |
| Relugolix | Relugolix (TAK-385)?is a potent, orally active, nonpeptidic gonadotropin-releasing hormone (GnRH) antagonist. Relugolix possesses high affinity and potent antagonistic activity for human receptor (binding IC50=0.33 nM) and monkey receptor (IC50=0.32 nM) compared with TAK-013 (HY-100209)[1]. Relugolix is used for the study of sex-hormone-dependent diseases, such as including endometriosis, uterine fibroids and prostate cancer et al[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAK-385. CAS No. 737789-87-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16474. | |
| Relutrigine | Relutrigine (PRAX-562) is an orally active inhibitor of persistent sodium channel. Relutrigine potently and preferentially inhibits persistent INa induced by ATX-II (Nav 1.5 activator) or the SCN8A mutation N1768D with IC50 values of 141 nM and 75 nM, respectively. Relutrigine exhibits potent use-dependent block and reduces neuronal intrinsic excitability. Relutrigine has effective anticonvulsant activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PRAX-562. CAS No. 2392951-29-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148792. | |
| rel-VU6021625 | rel-VU6021625 is the relative configuration of VU6021625 (HY-160440A). VU6021625 is a potent and selective mAChR M4 antagonist with IC50 values of 0.44 nM and 57 nM for human M4, rat M4, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2307718-96-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-160440. | |
| REM127 | REM127 is a small molecule compound capable of modulating calcium homeostasis in cells and possesses neuroprotective effects. REM127 can restore the calcium homeostasis imbalance in cellular models caused by pathological accumulation of tau protein. REM127 can efficiently cross the blood-brain barrier, and it has the potential to rescue synaptic and cognitive deficits in Alzheimer's disease animal models, as well as to slow down the progression of amyloid-beta and tau protein pathologies. REM127 can be used for research in neurodegenerative diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1417823-67-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-162566. | |
| Remdesivir | Remdesivir (GS-5734) is a nucleoside analogue with effective antiviral activity. Remdesivir can inhibit the synthesis of viral DNA or RNA. Remdesivir can be used for the research of infection, such as SARS-CoV and MHV infection[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS-5734. CAS No. 1809249-37-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-104077. | |
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