MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Remdesivir nucleoside monophosphate | Remdesivir nucleoside monophosphate is a metabolite of Remdesivir (HY-104077). Remdesivir is a nucleoside analogue with effective antiviral activity. Remdesivir can inhibit the synthesis of viral DNA or RNA. Remdesivir can be used for the research of infection, such as SARS-CoV and MHV infection[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1911578-74-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-44358. |  |
| Remibrutinib | Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood[1]. Remibrutinib has the potential for Chronic urticaria (CU) treatment[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LOU064. CAS No. 1787294-07-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-128757. | |
| Remlifanserin | Remlifanserin (ACP-204) is a highly selective 5-HT2A inverse agonist. Remlifanserin is applicable to research related to Alzheimer's disease psychosis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACP-204. CAS No. 2289704-13-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159831. | |
| Remodelin | Remodelin is an orally active and selective inhibitor of acetyltransferase NAT10. Remodelin inhibits NAT10 activitity and slows DNA replication and suppresses growth of prostate cancer cells. Remodelin inhibits the growth of prostate cancer and hepatocellular carcinoma in xenograft model. Remodelin enhances the healthspan in hutchinson-gilford progeria syndrome (HGPS) mouse model[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 949912-58-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16706. | |
| Remodelin hydrobromide | Remodelin hydrobromide is an orally active and selective inhibitor of acetyltransferase NAT10. Remodelin hydrobromide inhibits NAT10 activitity and slows DNA replication and suppresses growth of prostate cancer cells. Remodelin hydrobromide inhibits the growth of prostate cancer and hepatocellular carcinoma in xenograft model. Remodelin hydrobromide enhances the healthspan in hutchinson-gilford progeria syndrome (HGPS) mouse model[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1622921-15-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-16706A. | |
| Remogliflozin | Remogliflozin is a potent and selective inhibitor of SGLT2 (sodium-glucose cotransporter 2) with Kis of 12.4 and 26 nM for human and rat SGLT2, respectively. Remogliflozin is the active form of Remogliflozin etabonate(HY-14945)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Remogliflozin A. CAS No. 329045-45-6. Pack Sizes: 5 mg. Product ID: HY-13414. | |
| Remternetug | Remternetug (LY3372993) is a monoclonal antibody that targets pyroglutamylated amyloid β fibrils (N3pG-Aβ). Remternetug specifically binds to N3pG-Aβ, thereby clearing amyloid plaques in the brain and reducing amyloid burden. Remternetug can be used in research related to Alzheimer's disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY3372993. CAS No. 2571940-41-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990078. | |
| Rencofilstat | Rencofilstat (CRV431) is an orally active pan-cyclophilin inhibitor with IC50 values of 2.5 nM, 3.1 nM, 2.8 nM, 7.3 nM for Cyp A, CypB, Cyp D and Cyp G, respectively. Rencofilstat reduces fibrosis and tumor growth in models of chronic liver disease. Rencofilstat can be used for the study of nonalcoholic steatohepatitis (NASH), hepatocellular carcinoma and viral hepatitis-induced liver disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CRV431. CAS No. 1383420-08-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-135644. | |
| Rennin | Rennin, also known as Chymosin, is a pepsin-related proteolytic enzyme synthesized by cells in the stomach of certain animals that efficiently converts liquid milk into a semi-solid, allowing it to remain in the stomach for longer. The natural substrate of Rennin is K-casein, which is specifically cleaved at the peptide bond between amino acid residues 105 and 106, phenylalanine and methionine, and is widely used in cheese production[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EC 3.4.23.4. CAS No. 9001-98-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P2810. | |
| Rentosertib | Rentosertib (INS018 055) (compound 112) is the orally active TNIK and MAP4K4 inhibitor with IC50 values of 12-120, 12-120 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: INS018_055; TNIK&MAP4K4-IN-2. CAS No. 2828567-39-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-160623. | |
| Renvistobart | Renvistobart is an immunoglobulin G1-κ, anti-[Homo sapiens TIGIT (T cell immunoreceptor with Ig domain and ITIM, VSIG9, VSTM3)] Homo sapiens monoclonal antibody[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-986207; ONO-4686. CAS No. 2725062-35-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990079. | |
| Reozalimab | Reozalimab is a bispecific antibody targeting to PD-1/PD-L1. Reozalimab mediates antibody-dependent cell cytotoxicity in cancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY3434172; IBI-318. CAS No. 2445259-99-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9996. | |
| Repaglinide | Repaglinide is an insulin secretagogue for the treatment of type-2 diabetes mellitus[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AG-EE 623ZW. CAS No. 135062-02-1. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-15209. | |
| Repaglinide-d5 | Repaglinide-d5 is deuterium labeled Repaglinide. Repaglinide is an insulin secretagogue for the treatment of type-2 diabetes mellitus[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AG-EE 623ZW d5. CAS No. 1217709-85-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15209S. | |
| Reparixin | Reparixin is a non-competitive allosteric inhibitor of the chemokine receptors CXCR1 and CXCR2 activation with IC50s of 1 and 100 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Repertaxin; DF 1681Y. CAS No. 266359-83-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15251. | |
| Reparixin L-lysine salt | Reparixin L-lysine salt is an allosteric inhibitor of chemokine receptor 1/2 (CXCR1/2) activation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Repertaxin L-lysine salt. CAS No. 266359-93-7. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-15252. | |
| Repotrectinib | Repotrectinib (TPX-0005) is a potent ROS1 (IC50=0.07 nM) and TRK (IC50=0.83/0.05/0.1 nM for TRKA/B/C) inhibitor. Repotrectinib potently inhibits WT ALK (IC50=1.01 nM). Repotrectinib has anti-cancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TPX-0005. CAS No. 1802220-02-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103022. | |
| Reproterol | Reproterol is a selective β2-adrenoceptor agonist and cAMP phosphodiesterase (PDE) inhibitor. Reproterol inhibits adenylate cyclase-induced phosphodiesterase activity. Reproterol inhibits histamine release from mast cells. Reproterol is applicable to research related to asthma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 54063-54-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-135490. | |
| RepSox | RepSox (E-616452) is a potent and selective transforming growth factor-beta receptor I/activin like kinase 5 (TGF-β-RI/ALK5) inhibitor. RepSox inhibits ALK5 autophosphorylation with an IC50 value of 4 nM. RepSox can be used for the research of obesity and associated metabolic diseases such as type 2 diabetes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E-616452; SJN 2511. CAS No. 446859-33-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13012. | |
| RepSox (GMP) | RepSox (E-616452) (GMP) is a RepSox (HY-13012) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. RepSox is a potent and selective TGF-β-RI/ALK5 inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E-616452 (GMP); SJN 2511 (GMP). CAS No. 446859-33-2. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-13012G. | |
| RESA peptide | RESA peptide is a substrate peptide of β-adrenergic receptor kinase (βARK). RESA peptide serves as a substrate for βARK-mediated phosphorylation, and its N-terminal acidic residues enhance phosphorylation efficiency and substrate binding capacity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 133699-13-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P11765. | |
| Resatorvid | Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor. Resatorvid inhibits NO, TNF-α and IL-6 production with IC50s of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy and plays pivotal role in various inflammatory diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAK-242; CLI-095. CAS No. 243984-11-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11109. | |
| Resazurin sodium | Resazurin sodium (Diazoresorcinol sodium) is a non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin sodium is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin sodium can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Diazoresorcinol sodium. CAS No. 62758-13-8. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-111391. | |
| Resazurin sodium, indicator | Resazurin (Diazoresorcinol) sodium, indicator is a non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin sodium, indicator is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin sodium, indicator can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Diazoresorcinol sodium, indicator. CAS No. 62758-13-8. Pack Sizes: 1 g; 5 g. Product ID: HY-111391A. | |
| Reserpine | Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2). Uses: Scientific research. Category: Induced disease models products. CAS No. 50-55-5. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-N0480. | |
| Reserpine (Standard) | Reserpine (Standard) is the analytical standard of Reserpine. This product is intended for research and analytical applications. Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2). Uses: Scientific research. Category: Signaling pathways. CAS No. 50-55-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0480R. | |
| Resibufogenin | Resibufogenin is an orally active anticancer agent. Resibufogenin can be extracted from toad venom. Resibufogenin blocks signaling pathways such as PI3K/Akt, NF-κB, AP-1, activates GSK-3β, and regulates cyclin D1. Resibufogenin can activate central neurons. Resibufogenin has anti-inflammatory activity. Resibufogenin has anti-tumor effects on a variety of tumors such as multiple myeloma, renal cancer, colorectal cancer, pancreatic cancer, and glioma[1][2][3][4][5][6][7][8][9]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bufogenin; Recibufogenin. CAS No. 465-39-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-N0815. | |
| Resigratinib | Resigratinib (KIN-3248) is an irreversible and orally active covalent inhibitor of FGFR1-4 that effectively inhibits wild-type and drug-resistant mutations (such as FGFR2 V565F, FGFR3 V555M). Resigratinib covalently binds to the Cys492 site of FGFR, blocks the FGFR signaling pathway, inhibits tumor cell proliferation and induces apoptosis. Resigratinib can be used for the study of FGFR2/3-driven solid tumors (such as cholangiocarcinoma and bladder cancer)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KIN-3248. CAS No. 2750709-91-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156632. | |
| Resiniferatoxin | Resiniferatoxin ((+)-Resiniferatoxin), is a selective agonist of transient receptor potential vanilloid 1 (TRPV1) receptor agonist. Resiniferatoxin can be isolated from the Euphorbia resinifera plant. Resiniferatoxin eliminates TRPV1+ primary sensory afferents and blunt cardiac sympathetic afferent reflex for a relatively long period[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-Resiniferatoxin. CAS No. 57444-62-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2333. | |
| Resiquimod | Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α. Uses: Scientific research. Category: Induced disease models products. Alternative Names: R848; S28463. CAS No. 144875-48-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-13740. | |
| Resiquimod-d5 | Resiquimod-d5 is deuterium labeled Resiquimod. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R848-d5; S28463-d5. CAS No. 2252319-44-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-13740S. | |
| Resiquimod (GMP) | Resiquimod (R848) (GMP) is Resiquimod (HY-13740) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist. Resiquimod (GMP) can induce human mMDSC to mature into inflammatory macrophages[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R848 (GMP); S28463 (GMP). CAS No. 144875-48-9. Pack Sizes: 10 mg; 50 mg. Product ID: HY-13740G. | |
| Reslizumab | Reslizumab (Sch 55700) is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma. Reslizumab is effective in neutralizing the function of IL-5. Reslizumab has high binding affinity for human IL-5, with KD values of 109 pM and 4.3 pM in the the Biacore surface plasmon resonance and Kinetic Exclusion Assay, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sch 55700; CDP-835; JES1-39D10. CAS No. 241473-69-8. Pack Sizes: 1 mg; 2 mg. Product ID: HY-P9949. | |
| Resmetirom | Resmetirom (MGL-3196) is a highly selective and orally active thyroid hormone receptor β (THR-β) agonist with an EC50 value of 0.21 μM. Resmetirom can be used for the study of noncirrhotic nonalcoholic steatohepatitis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MGL-3196; VIA-3196. CAS No. 920509-32-6. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-12216. | |
| Resminostat | Resminostat (RAS2410; 4SC-201) is a potent inhibitor of HDAC1, HDAC3 and HDAC6, with mean IC50 values of 42.5, 50.1, 71.8 nM, respectively, and shows less potent activities against HDAC8, with an IC50 of 877 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RAS2410; 4SC-201. CAS No. 864814-88-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14718. | |
| Resminostat hydrochloride | Resminostat hydrochloride is a potent inhibitor of HDAC1, HDAC3 and HDAC6, with mean IC50 values of 42.5, 50.1, 71.8 nM, respectively, and shows less potent activities against HDAC8, with an IC50 of 877 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RAS2410 hydrochloride; 4SC-201 hydrochloride. CAS No. 1187075-34-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14718A. | |
| Resolvin D2 | Resolvin D2 is a metabolite of docosahexaenoic acid (DHA), with anti-inflammatory, anti-infective activities. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Resolvin D2 is a remarkably potent inhibitor of TRPV1 (IC50 = 0.1 nM) and TRPA1 (IC50 = 2 nM) in primary sensory neurons[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RvD2. CAS No. 810668-37-2. Pack Sizes: 25 μg (265.6 μM * 250 μL in Ethanol); 50 μg (265.6 μM * 500 μL in Ethanol). Product ID: HY-121636. | |
| Resolvin E1 | Resolvin E1 (RvE1), a potent endogenous pro-resolving mediator of inflammation, is derived from omega-3 fatty acid eicosapentaenoic acid (EPA). Resolvin E1 is endogenously biosynthesized from EPA in the presence of Aspirin during the spontaneous resolution phase of acute inflammation, where specific cell-cell interactions occur. Resolvin E1 possesses unique counterregulatory actions that inhibit polymorphonuclear leukocyte (PMN) transendothelial migration. Resolvin E1 also acts as a potent inhibitor of leukocyte infiltration, dendritic cell migration, and IL-12 production[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RvE1. CAS No. 552830-51-0. Pack Sizes: 10 μg (285.3 μM * 100 μL in Ethanol); 25 μg (285.3 μM * 250 μL in Ethanol). Product ID: HY-114041. | |
| (R)-Esomeprazole | (R)-Esomeprazole ((R)-Omeprazole; (+)-Omeprazole) is an orally active cytochrome P450 2C19, CYP3A4, and CYP2C9-related metabolic modulator. (R)-Esomeprazole can be used in studies of digestive system diseases and compound metabolic interactions[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-Omeprazole; (+)-Omeprazole. CAS No. 119141-89-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Z2667. | |
| Resorufin | Resorufin (NSC 12097) is a highly fluorescent pink dye. Resorufin shows favorable properties such as water solubility, red-shifted absorption/emission signals. Resorufin is used for the detection of ROS/RNS and a second analyte[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 12097. CAS No. 635-78-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-123533. | |
| Resorufin sodium salt | Resorufin sodium salt (NSC 12097) is a highly fluorescent pink dye. Resorufin sodium salt shows favorable properties such as water solubility, red-shifted absorption/emission signals. Resorufin sodium salt is used for the detection of ROS/RNS and a second analyte[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 12097 sodium salt. CAS No. 34994-50-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-123533A. | |
| Resugosbart | Resugosbart is an anti-SOST human IgG4 κ monoclonal antibody[1]. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003). Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: SHR-1222. CAS No. 2647412-09-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P990696. | |
| Resveratrol | Resveratrol (trans-Resveratrol; SRT501) is a CNS-penetrant natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator[1][2][3][4][8]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor[5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model[6]. Resveratrol increases production of NO in endothelial cells[7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: trans-Resveratrol; SRT501. CAS No. 501-36-0. Pack Sizes: 10 mM * 1 mL in DMSO; 200 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-16561. | |
| Resveratrol (Standard) | Resveratrol (Standard) is the analytical standard of Resveratrol. This product is intended for research and analytical applications. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator[1][2][3][4]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor[5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model[6]. Resveratrol increases production of NO in endothelial cells[7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: trans-Resveratrol (Standard); SRT501 (Standard). CAS No. 501-36-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16561R. | |
| Retagliptin | Retagliptin (SP2086) is a selective, competitive and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. Retagliptin can be used for type 2 diabetes mellitus (T2DM) research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SP2086. CAS No. 1174122-54-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112668A. | |
| Retagliptin phosphate | Retagliptin phosphate (SP2086 phosphate) is a selective, competitive and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. Retagliptin phosphate can be used for type 2 diabetes mellitus (T2DM) research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SP2086 phosphate. CAS No. 1256756-88-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112668. | |
| Retapamulin | Retapamulin (SB-275833) is a topical antibiotic that binds Staphylococcus aureus and E. coli ribosomes with a Kd of 3 nM. Retapamulin can be used in researches of atopic dermatitis and prostate cancer[1][2][8]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SB-275833. CAS No. 224452-66-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17010. | |
| Retaspimycin Hydrochloride | Retaspimycin Hydrochloride is a potent inhibitor of Hsp90 with EC50s of 119 nM for both Hsp90 and Grp9. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IPI-504. CAS No. 857402-63-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10210. | |
| Retatrutide | Retatrutide (LY3437943) is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide binds human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide can be used for the research of obesity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY3437943. CAS No. 2381089-83-2. Pack Sizes: 1 mg. Product ID: HY-P3506. | |
| Reticuline | Reticuline shows anti-inflammatory effects through JAK2/STAT3 and NF-κB signaling pathways. Reticuline inhibits mRNA expressions of TNF-α, and IL-6 and reduces the phosphorylation levels of JAK2 and STAT3[1]. Reticuline exhibits cardiovascular effects[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 485-19-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1356. | |
| (±)-Reticuline | (±)-Reticuline (compound 3f) is a natural product obtained from Peumus boldus Molina. (±)-Reticuline can be used to synthesize S-Reticuline[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1699-46-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-135489. | |
| Retifanlimab | Retifanlimab is an anti-programmed cell death protein 1 (anti-PD-1) monoclonal antibody (mAb). Retifanlimab can be used for the research of gastroesophageal adenocarcinoma (GEA)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: INCMGA-00012; MGA-012. CAS No. 2079108-44-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99941. | |
| Retinoic acid | Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Vitamin A acid; all-trans-Retinoic acid; ATRA. CAS No. 302-79-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-14649. | |
| Retinoic acid-d5 | Retinoic acid-d5 is the the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitamin A acid-d5; all-trans-Retinoic acid-d5; ATRA-d5. CAS No. 78996-15-3. Pack Sizes: 500 μg; 1 mg. Product ID: HY-14649S4. | |
| Retinoic acid (GMP) | Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitamin A acid (GMP); all-trans-Retinoic acid (GMP); ATRA (GMP). CAS No. 302-79-4. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-14649G. | |
| Retinoic acid (Standard) | Retinoic acid (Standard) is the analytical standard of Retinoic acid. This product is intended for research and analytical applications. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitamin A acid (Standard); all-trans-Retinoic acid (Standard); ATRA (Standard). CAS No. 302-79-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-14649R. | |
| Retinyl acetate | Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Retinol acetate; Vitamin A acetate. CAS No. 127-47-9. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-N0679. | |
| Retinyl acetate (Standard) | Retinyl acetate (Standard) is the analytical standard of Retinyl acetate. This product is intended for research and analytical applications. Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Retinol acetate (Standard); Vitamin A acetate (Standard). CAS No. 127-47-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0679R. | |
| Retinyl palmitate | Retinyl palmitate is an ester of Retinol and is the major form of vitamin A found in the epidermis. Retinyl palmitate has been widely used in researches of pharmaceutical and cosmetic formulations[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitamin A palmitate; Retinol palmitate. CAS No. 79-81-2. Pack Sizes: 10 mM * 1 mL in Ethanol; 100 mg. Product ID: HY-B1384. | |
| Retosiban | Retosiban (GSK221149A) is a potent, selective, and orally active oxytocin receptor antagonist (Ki (hOT) = 0.65 nM, Ki (rOT) = 4.1 nM) with no detectable agonist activity. Retosiban has nanomolar affinity for the oxytocin receptor with >1400-fold selectivity over the closely related vasopressin receptors. Retosiban inhibits spontaneous and induces uterine contractions. Retosiban can be studied in research for preterm labour[1][2][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GSK 221149; GSK 221149A. CAS No. 820957-38-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14778. | |
| RETRA | RETRA is a RIPK1/RIPK3/MLKL and p73 activator. RETRA mediates plasma membrane disruption, induces ROS accumulation, triggers early mitochondrial hyperpolarization, and synergistically drives necroptosis. RETRA inhibits cancer cells carrying mutant p53 via a p73-dependent salvage pathway. RETRA can be used in research related to cervical cancer and cancers with mutant p53[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1036069-26-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108636. | |
| Retro-2 | Retro-2 is a selective inhibitor of retrograde protein trafficking at the endosome-trans-Golgi network interface. Retro-2 is an ebolavirus (EBOV) infection inhibitor with an EC50 of 12.2 μM in HeLa cells. Retro-2 induces cell autophagy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1201652-50-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122571. | |
| Retro-2 cycl | Retro-2 cycl (RN 1-001) is a retrograde transport inhibitor with antiviral activity. Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudoviruses, with an IC50 of 54 μM and 160 μM respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RN 1-001. CAS No. 1429192-00-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114698. | |
| RET V804M-IN-1 | RET V804M-IN-1 (compound 5) is a wt-RET -selective inhibitors of RETV804M kinase, with an IC50 of 20 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2414909-94-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136534. | |
| Reuterin | Reuterin is a broad-spectrum antimicrobial agent active against Gram positive and Gram negative bacteria, as well as yeasts, moulds and protozoa. Reuterin is produced by specific strains of Lactobacillus reuteri during anaerobic metabolism of glycerol. Reuterin also demonstrates potent antimicrobial activity against a broad panel of human and poultry meat campylobacter spp. Isolates[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3-Hydroxypropionaldehyde; 3-Hydroxypropanal. CAS No. 2134-29-4. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N8461. | |
| REV7/REV3L-IN-1 | REV7/REV3L-IN-1 is a REV7/REV3L interaction inhibitor with an IC50 of 78 μM. REV7/REV3L-IN-1 binds directly to REV7 and inhibits its interaction with REV3L. REV7/REV3L-IN-1 inhibits interstrand crosslink repair in cells. REV7/REV3L-IN-1 chemosensitizes cancer cells to Cisplatin (HY-17394). REV7/REV3L-IN-1 can be used in cervical cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1979192-13-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100468. | |
| Revefenacin | Revefenacin (TD-4208; GSK1160724) is a potent mAChR antagonist; has a high affinity on M3 receptor with a Ki of 0.18 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TD-4208; GSK1160724. CAS No. 864750-70-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15851. | |
| Reversan | Reversan (CBLC4H10) inhibits drug efflux mediated by P-glycoprotein (Pgp) and multidrug resistance protein 1 (MRP1), and exhibits oral activity. Reversan shows activity against glioblastoma multiforme and neuroblastoma models[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CBLC4H10. CAS No. 313397-13-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107643. | |
| Reverse T3 | Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine[1]. Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3,5,3-Triiodothyronine. CAS No. 5817-39-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W010696. | |
| Reverse T3 (Standard) | Reverse T3 (Standard) is the analytical standard of Reverse T3. This product is intended for research and analytical applications. Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine[1]. Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3,5,3-Triiodothyronine (Standard). CAS No. 5817-39-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W010696R. | |
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