MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Cynaroside (Standard) | Cynaroside (Standard) is the analytical standard of Cynaroside. This product is intended for research and analytical applications. Cynaroside (Luteolin 7-glucoside) is a flavonoid compound that exhibits anti-oxidative capabilities. Cynaroside is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 32 nM. Cynaroside also is a promising inhibitor for H2O2-induced apoptosis, has cytoprotection against oxidative stress-induced cardiovascular diseases. Cynaroside also has antibacterial, antifungal and anticancer activities, antioxidant and anti-inflammatory activities[1][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Luteolin 7-glucoside (Standard); Luteolin 7-O-β-D-glucoside (Standard). CAS No. 5373-11-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0540R. |  |
| CYP3cide | CYP3cide (PF-4981517) is a potent, selective and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4). The IC50 values for Midazolam 1-hydroxylase activity are 0.03 μM, 17 μM, and 71 μM for CYP3A4, CYP3A5, and CYP3A7, respectively. CYP3cide can be used to distinguish the contributions of CYP3A4 versus CYP3A5 on agent metabolism[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-4981517. CAS No. 1390637-82-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18642. | |
| Cypate | Cypate, a cyanine dye, is a near infrared (NIR) fluorescent probe for in vivo tumor imaging[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 95837-47-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-D1719. | |
| Cyprodinil | Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CGA-219417. CAS No. 121552-61-2. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-116214. | |
| Cyproheptadine | Cyproheptadine is a potent and orally active 5-HT2A receptor antagonist, with antidepressant and antiserotonergic effects. Cyproheptadine has antiplatelet and thromboprotective activities. Cyproheptadine can be used for the research of thromboembolic disorders[1][2]. Uses: Scientific research. Category: Induced disease models products. CAS No. 129-03-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1622. | |
| Cyproheptadine hydrochloride | Cyproheptadine hydrochloride is a potent and orally active 5-HT2A receptor antagonist, with antidepressant and antiserotonergic effects. Cyproheptadine hydrochloride has antiplatelet and thromboprotective activities. Cyproheptadine hydrochloride can be used for the research of thromboembolic disorders[1][2]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Cyproheptadine HCl. CAS No. 969-33-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-B0366A. | |
| Cyproterone acetate | Cyproterone acetate is an anti-androgen (IC50=7.1 nM) and progestogen synthetic steroid. Cyproterone acetate has affinity with progesteron and with glucocorticoidal receptors[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 427-51-0. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 500 mg. Product ID: HY-13604. | |
| Cypyrafluone | Cypyrafluone is a 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor that prevents the homogentisic acid (HGA) production. Cypyrafluone can control weed in wheat fields[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Huanbifucaotong. CAS No. 1855929-45-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W725385. | |
| Cys-Gly-Tyr-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Gly-Gly | Cys-Gly-Tyr-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Gly-Gly is a13-mer synthetic peptide containing seven amino acids homologous to SV40 T antigen. Cys-Gly-Tyr-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Gly-Gly is capable of inducing nuclear transport[1]. Uses: Scientific research. Category: Peptides. CAS No. 104914-40-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3827. | |
| Cys-LT7 | Cys-LT7 is a transferrin receptor (TfR)-targeting peptide ligand. Cys-LT7 binds to a TfR site distinct from endogenous transferrin, mediates conjugated Doxorubicin (HY-15142A) delivery to TfR-overexpressed tumor cells, and exhibits low toxicity to TfR-low-expressed normal cells. Cys-LT7 is an L-configuration peptide susceptible to proteolytic enzymes, leading to poor biostability in peptide-drug conjugates. Cys-LT7 can be used for the research of glioblastoma, hepatocellular carcinoma, lung carcinoma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1254540-73-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P11099. | |
| Cys-McMMAF | Cys-McMMAF is the released payload of AlMcMMAF, an anti-5T4 humanized A1 antibody conjugated to the microtubule disrupting MMAF (HY-15579) via a maleimidocaproyl linker. Cys-McMMAF has antitumor efficacy in two tumor mouse models (H1975 and MDA-MB-361-DYT2 models)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1160590-05-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150233. | |
| Cys-MC-VC-PAB-MMAE | Cys-MC-VC-PAB-MMAE consists a cleavable ADC linker (Cys-MC-VC-PAB) and a potent tubulin inhibitor (MMAE). Cys-MC-VC-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3051855-32-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-171822. | |
| Cysmethynil | Cysmethynil is an Icmt inhibitor(IC50 = 2.4 μM). Cysmethynil inhibites RAS membrane binding and EGF signal transduction. Cysmethynil prevents the cells in the G1 phase and induces autophagy. Cysmethynil inhibits PC3 cells proliferation, has synergistic effect with Paclitaxel (HY-B0015) and Doxorubicin (HY-15142A). Cysmethynil has anti-tumor effects and can be used for solid tumor (such as prostate cancer et al.) research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 851636-83-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16160. | |
| Cys-Penetratin | Cys-Penetratin is a cysteine-containing cell-penetrating peptide with sequence CRQIKIWFQNRRMKWKK. Cys-Penetratin can Cys-Penetratin can be used for the research for the research of drug delivery[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 209323-98-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4093. | |
| Cystamine | Cystamine is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active transglutaminase (Tgase) inhibitor. Cystamine also has inhibition activity for caspase-3 with an IC50 value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD) [1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 51-85-4. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-124476. | |
| Cystamine dihydrochloride | Cystamine (dihydrochloride) is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active transglutaminase (Tgase) inhibitor. Cystamine also has inhibition activity for caspase-3 with an IC50 value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD) [1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 56-17-7. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W020050. | |
| Cystathionine-γ-lyase-IN-1 | Cystathionine-γ-lyase-IN-1 is a selective cystathionine γ-lyase (CSE) enzyme inhibitor with an IC50 of 6.3 μM[1]. Cystathionine-γ-lyase-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2165706-30-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136211. | |
| Cysteamine-d4 hydrochloride | Cysteamine-d4 (hydrochloride) is the deuterium labeled Cysteamine hydrochloride. Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Aminoethanethiol-d4 hydrochloride; 2-Mercaptoethylamine-d4 hydrochloride. CAS No. 1219805-04-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-77591S. | |
| Cysteamine hydrochloride | Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant. Uses: Scientific research. Category: Induced disease models products. Alternative Names: 2-Aminoethanethiol hydrochloride; 2-Mercaptoethylamine hydrochloride. CAS No. 156-57-0. Pack Sizes: 10 g; 25 g; 50 g; 100 g. Product ID: HY-77591. | |
| Cysteamine hydrochloride (Standard) | Cysteamine (hydrochloride) (Standard) is the analytical standard of Cysteamine (hydrochloride). This product is intended for research and analytical applications. Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Aminoethanethiol hydrochloride (Standard); 2-Mercaptoethylamine hydrochloride (Standard). CAS No. 156-57-0. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-77591R. | |
| Cysteine peptide | Cysteine peptide is a tyrosinase inhibitor with skin-whitening, antioxidant and multi-regulatory activities. Cysteine peptide inhibits enzyme activity and blocks melanin transport, effectively reducing UV-B-induced skin erythema and pigmentation. Cysteine peptide synergistically maintains skin health by quenching ROS, resisting oxidative stress and promoting pheomelanin production. Cysteine peptide safely prevents daily ultraviolet damage and supports moderate sun exposure for vitamin D synthesis. Cysteine peptide also acts as a plant signaling factor to regulate vegetative growth, development and stress resistance responses[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 845727-64-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P10533. | |
| Cysteinylglycine | Cysteinylglycine (L-Cysteinylglycine; Cys-Gly) is a dipeptide formed by the peptide bond linkage between cysteine (Cysteine) and glycine (Glycine). Cysteinylglycine is an important metabolic intermediate in the human body, mainly derived from the degradation of glutathione (GSH). Cysteinylglycine reduces ferric iron to ferrous iron, drives the redox cycle of iron, generates reactive oxygen species (ROS), stimulates oxidative reactions, induces lipid peroxidation of human plasma LDL lipoproteins, and causes oxidative damage to DNA bases. Cysteinylglycine can be used as a biomarker to evaluate ischemic heart disease, breast cancer and other conditions[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-Cysteinylglycine; Cys-Gly; H-Cys-Gly-OH. CAS No. 19246-18-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113110. | |
| Cysteinylglycine (Standard) | Cysteinylglycine (Standard) is the analytical standard of Cysteinylglycine. This product is intended for research and analytical applications. Cysteinylglycine is a dipeptide formed by the peptide bond linkage between cysteine (Cysteine) and glycine (Glycine). Cysteinylglycine is an important metabolic intermediate in the human body, mainly derived from the degradation of glutathione (GSH). Cysteinylglycine reduces ferric iron to ferrous iron, drives the redox cycle of iron, generates reactive oxygen species (ROS), stimulates oxidative reactions, induces lipid peroxidation of human plasma LDL lipoproteins, and causes oxidative damage to DNA bases. Cysteinylglycine can be used as a biomarker to evaluate ischemic heart disease, breast cancer and other conditions[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-Cysteinylglycine (Standard); Cys-Gly (Standard); H-Cys-Gly-OH (Standard). CAS No. 19246-18-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113110R. | |
| Cys-V5 Peptide | Cys-V5 Peptide, a tag peptide, is the V5 Peptide with an N-terminal cysteine. Cys-V5 Peptide can be used to label proteins[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 922704-46-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5969. | |
| CYT296 | CYT296 is a target chromatin de-condensation compound. CYT296 can improve the induction of induced pluripotent stem cell (iPSCs) mediated by defined factors (OSKM) and induce an open chromatin state in Mouse Embryonic Fibroblast (MEFs) to facilitate somatic cell reprogramming. CYT296 can be used for cell replacement therapies and drug screening research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1799392-31-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-141591. | |
| Cytarabine | Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV. Cytarabine shows anti-orthopoxvirus activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cytosine β-D-arabinofuranoside; Cytosine Arabinoside; Ara-C. CAS No. 147-94-4. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-13605. | |
| Cytarabine hydrochloride | Cytarabine hydrochloride, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine hydrochloride has antiviral effects against HSV. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cytosine β-D-arabinofuranoside hydrochloride; Cytosine Arabinoside hydrochloride; Ara-C hydrochloride. CAS No. 69-74-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-13605A. | |
| Cytarabine (Standard) | Cytarabine (Standard) is the analytical standard of Cytarabine. This product is intended for research and analytical applications. Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV. Cytarabine shows anti-orthopoxvirus activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cytosine β-D-arabinofuranoside (Standard); Cytosine Arabinoside (Standard); Ara-C (Standard). CAS No. 147-94-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13605R. | |
| Cytidine | Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cytosine β-D-riboside; Cytosine-1-β-D-ribofuranoside. CAS No. 65-46-3. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B0158. | |
| Cytidine 5'-diphosphate trisodium salt (Standard) | Cytidine 5'-diphosphate (trisodium salt) (Standard) is the analytical standard of Cytidine 5'-diphosphate (trisodium salt). This product is intended for research and analytical applications. Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CDP (Standard). CAS No. 34393-59-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W008915R. | |
| Cytidine 5'-monophosphate | Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5'-Cytidylic acid; 5'-CMP. CAS No. 63-37-6. Pack Sizes: 10 mM * 1 mL in Water; 1 g; 5 g. Product ID: HY-W009162. | |
| Cytidine 5-monophosphate-13C9,15N3 dilithium | Cytidine 5-monophosphate-13C9,15N3 (5'-Cytidylic acid-13C9,15N3 dilithium; 5'-CMP-13C9,15N3) dilithium is 13C and 15N-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5'-Cytidylic acid-13C9,15N3 dilithium; 5'-CMP-13C9,15N3 dilithium. CAS No. 2483830-57-3. Pack Sizes: 1 mg (100 mM in 28.82 μL Tris HCl * H2O buffer pH=7.5). Product ID: HY-W009162S5. | |
| Cytidine-5'-triphosphate | Cytidine 5-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5-triphosphate from uridine 5-triphosphate (UTP). Cytidine 5-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cytidine triphosphate; 5'-CTP. CAS No. 65-47-4. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-125818. | |
| Cytidine-5'-triphosphate disodium | Cytidine-5'-triphosphate (Cytidine triphosphate; 5'-CTP) disodium is a nucleoside triphosphate, that is invovled in biosynthesis of DNA, RNA and lipid. Cytidine triphosphate synthase can catalyze the formation of cytidine 5-triphosphate from uridine 5-triphosphate (UTP). Cytidine 5-triphosphate disodium is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cytidine triphosphate disodium; 5'-CTP disodium. CAS No. 36051-68-0. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W013100. | |
| Cytisinicline | Cytisinicline (Cytisine) is an alkaloid. Cytisinicline (Cytisine) is a partial agonist of α4β2 nAChRs[1], and partial to full agonist at β4 containing receptors and α7 receptors[2]. Has been used medically to help with smoking cessation[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cytisine; Sophorine; Baptitoxine. CAS No. 485-35-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-N0175. | |
| Cytisinicline (Standard) | Cytisinicline (Standard) is the analytical standard of Cytisinicline. This product is intended for research and analytical applications. Cytisinicline (Cytisine) is an alkaloid. Cytisinicline (Cytisine) is a partial agonist of α4β2 nAChRs[1], and partial to full agonist at β4 containing receptors and α7 receptors[2]. Has been used medically to help with smoking cessation[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cytisine (Standard); Sophorine (Standard); Baptitoxine (Standard). CAS No. 485-35-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0175R. | |
| Cytochalasin A | Cytochalasin A is a cell-permeable fungal toxin that is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50=3 μM) and inhibits actin polymerization and interferes with microtubule assembly by reacting with sulfhydryl groups. Antibiotic and fungicidal activitives[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 14110-64-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N6773. | |
| Cytochalasin B | Cytochalasin B is a cell-permeable mycotoxin binding to the barbed end of actin filaments, disrupting the formation of actin polymers, with Kd value of 1.4-2.2 nM for F-actin. Cytochalasin B blocks cell migration. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Phomin. CAS No. 14930-96-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-16928. | |
| Cytochalasin C | Cytochalasin C is a cell-permeable fungal toxin and induces the formation of nuclear rodlets. Cytochalasin C is 10 times less toxic in mice than is cytochalasin D[1][2][3]. Uses: Scientific research. Category: Natural products. CAS No. 22144-76-9. Pack Sizes: 1 mg. Product ID: HY-N6774. | |
| Cytochalasin D | Cytochalasin D (Zygosporin A) is a potent actin polymerization inhibitor, could be derived from fungus. Cytochalasin D has cell-permeable activity. Cytochalasin D inhibits the G-actin-cofilin interaction by binding to G-actin. Cytochalasin D also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells. Cytochalasin D can reduce exosome release, in turn reducing the amount of survivin present in the tumour environment. Cytochalasin D induces phosphorylation and cytoplasmic retention of Yap[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Zygosporin A; NSC 209835. CAS No. 22144-77-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N6682. | |
| Cytochrome C | Cytochrome C is a multi-functional enzyme involving in life and death decisions of the cell. Cytochrome C is essential in mitochondrial electron transport and intrinsic type II apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9007-43-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-125857. | |
| Cytochrome C (bovine heart) | Cytochrome C (bovine heart) is composed of 104 amino acids and is a nuclear-encoded mitochondrial protein. Cytochrome C (bovine heart) acts as an effective ROS scavenger, but when combined with the cofactor p66Shc, it promotes the generation of ROS to initiate apoptosis. Cytochrome C (bovine heart) can act as a single electron carrier[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9007-43-6. Pack Sizes: 50 mg; 100 mg; 200 mg. Product ID: HY-125857C. | |
| Cytochrome C (equine heart) | Cytochrome C (equine heart) is composed of 104 amino acids and is a nuclear-encoded mitochondrial protein. Cytochrome C (equine heart) is involved in mitochondrial electron transport and intrinsic type II apoptosis. Cytochrome C (equine heart) can act as a single electron carrier[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9007-43-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125857A. | |
| Cytosine | Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging. Cytosine can be used in cancer research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 71-30-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 5 g; 10 g; 25 g; 50 g; 100 g; 250 g; 500 g; 1000 g. Product ID: HY-I0626. | |
| Cytosine-13C,15N2 | Cytosine-13C,15N2 is the 13C and 15N labeled Cytosine[1]. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging[2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 181517-10-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-I0626S1. | |
| Cytosine-d2 | Cytosine-d2 is the deuterium labeled Cytosine[1]. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging[2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 106391-24-6. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-I0626S2. | |
| Cytosporone B | Cytosporone B (Csn-B; Dothiorelone G) is a naturally occurring nuclear orphan receptor Nur77/NR4A1 agonist with an EC50 of 0.278 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Csn-B; Dothiorelone G. CAS No. 321661-62-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2148. | |
| CYY292 | CYY292 is an FGFR1 inhibitor that specifically targets the FGFR1/AKT/Snail pathway in GBM cells. CYY292 dose-dependently inhibits cancer cell proliferation, epithelial-mesenchymal transition, stemness, invasion, and migration in vitro[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2644673-04-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162153. | |
| CZ415 | CZ415 is a potent and highly selective mTOR inhibitor with a pIC50 of 8.07. CZ415 inhibits mTORC1 and mTORC2 protein complex. Uses: Scientific research. Category: Signaling pathways. CAS No. 1429639-50-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100222. | |
| D13-9001 | D13-9001 is a potent AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) inhibitor with the KD values of 1.15 μM and 3.57 μM in E. coli and P. aeruginosa, respectively[1]. D13-9001 exhibits antibiotic activities[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 957471-96-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124819. | |
| D159687 | D159687 is a selective PDE4D inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1155877-97-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15444. | |
| D-3263 hydrochloride | D-3263 hydrochloride is an enteric-coated, orally bioavailable (transient receptor potential melastatin member 8) TRPM8 agonist. Uses: Scientific research. Category: Signaling pathways. CAS No. 1008763-54-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16162A. | |
| D-(-)-3-Phosphoglyceric acid disodium | D-(-)-3-Phosphoglyceric acid (3-Phospho-D-glyceric acid) disodium is an important intermediate in the enzyme-catalyzed glycolysis process. D-(-)-3-Phosphoglyceric acid disodium competitively inhibits yeast enolase (enolase). D-(-)-3-Phosphoglyceric acid disodium can regulate the activity of phosphoglycerate dehydrogenase (PHGDH) to modulate p53 protein and apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3-Phospho-D-glyceric acid disodium. CAS No. 80731-10-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141412. | |
| D4476 | D4476 is a potent, selective and cell-permeable inhibitor of casein kinase 1(CK1) with an IC50 value of 0.3 μM in vitro. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Casein Kinase I Inhibitor. CAS No. 301836-43-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10324. | |
| D4-abiraterone | D4-abiraterone is a major metabolite of abiraterone. D4-abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid-5a-reductase (SRD5A) and also an antagonist of androgen receptor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Δ4-Abiraterone; CB-7627; Abiraterone D4A metabolite. CAS No. 154229-21-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-109619. | |
| D574-0246 | D574-0246 is a dual-activity inhibitor of OXCT1, inhibiting both the ketolytic and succinyltransferase activities of OXCT1. D574-0246 reduces substrate-specific (LACTB K284) and global protein succinylation and decreases OXCT1 ketolytic activity in HepG2 cells. D574-0246 inhibits the viability of HCC cells (IC50: 16.49 μM in PLC cells, 6.656 μM in HepG2 cells). D574-0246 exerts anti-tumor efficacy in nude mice bearing OXCT1-overexpressing HepG2 xenograft tumors. D574-0246 can be used for the study of hepatocellular carcinoma (HCC)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: iOXCT1. CAS No. 1269110-12-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-178018. | |
| D5D-IN-326 | D5D-IN-326 is a selective, orally active delta-5 desaturase (D5D) inhibitor, with IC50s of 72 and 22 nM for rat and human D5D in enzymic and cell-based assays, respectively, has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and decreases body weight in diet-induced obese C57BL/6J mice[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1236767-85-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117427. | |
| D609 | D609, an antitumoural xanthate, is a specific and competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor with a Ki of 6.4 μM. D609 is an antioxidative protector and has antiviral and anti-inflammatory activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 83373-60-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-70072. | |
| D75-4590 | D75-4590, a pyridobenzimidazole derivative and a β-1,6-glucan synthesis inhibitor, possesses antifungal activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 384376-42-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134655. | |
| D927 | D927 (DS11252927) is an orally active glucose transporter type 4 (GLUT4) translocation activator with an EC50 of 0.14 μM. D927 enhances the binding affinity of PI3Kα catalytic subunit p110α to canonical RAS proteins (KRAS4A, KRAS4B) and RRAS, RRAS2, MRAS. D927 activates the PI3Kα-AKT pathway (increasing phosphorylation of AKT, p70S6 kinase) without affecting the RAF-ERK1/2 pathway. D927 improves hyperglycemia in type 1 and type 2 diabetes mice model. D927 can be used for the study of glucose homeostasis disorders and diabetes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DS11252927. CAS No. 2253733-37-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128574. | |
| DA-023 | DA-023 (Compound 4) is a selective positive allosteric modulator (PAM) of EAAT2 with an EC50 value of 1 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2585643-97-4. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg. Product ID: HY-162454. | |
| DA 3003-2 | DA 3003-2 is a potent and selectively Cdc25 inhibitor. DA 3003-2 shows antiproliferative activity. DA 3003-2 induces cell cycle arrest at the G2/M phase and increases the expression of P-tyr15 Cdc2. DA 3003-2 has the potential for the research of prostate cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC663285. CAS No. 383907-47-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-118798. | |
| DA-7867 | DA-7867 is an antibacterial compound with activity against a wide range of bacteria, including drug-resistant bacteria. DA-7867 shows promising antibacterial activity against some clinically important pathogens, including drug-resistant bacteria. It is an amide analog of Tedizolid (HY-14855), reflecting the potential use of tetrazoles in the development of new antibacterial agents[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 380382-38-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-117742. | |
| Dabcyl acid | Dabcyl acid (Dabcyl) is a nonfluorescent chromophore and a quencher. Dabcyl acid can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DABCYL; Para-methyl red. CAS No. 6268-49-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 25 g. Product ID: HY-D1045. | |
| Dabigatran | Dabigatran (BIBR 953), an oral anticoagulant, is a reversible, potent, competitive direct thrombin inhibitor (Ki=4.5 nM). Dabigatran (BIBR 953) also inhibits thrombin-induced platelet aggregation (IC50=10 nM)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIBR 953; BIBR 953ZW. CAS No. 211914-51-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10163. | |
| Dabigatran etexilate | Dabigatran etexilate (BIBR 1048) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin). Dabigatran etexilate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIBR 1048. CAS No. 211915-06-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10274. | |
| Dabigatran etexilate mesylate | Dabigatran etexilate mesylate (BIBR 1048MS) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin). Dabigatran etexilate mesylate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIBR 1048MS; Dabigatran etexilate methanesulfonate. CAS No. 872728-81-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-10274A. | |
| Dabigatran ethyl ester | Dabigatran ethyl ester is an inhibitor of ribosyldihydronicotinamide dehydrogenase (NQO2) and thrombin. Dabigatran ethyl ester inhibits NADH-dependent metabolism of mitomycin C mediated by purified recombinant human NQO2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 429658-95-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17378. | |
| Dabogratinib | Dabogratinib (TYRA-300) is an orally active, selective FGFR3 inhibitor with an IC50 of 11 nM. Dabogratinib exhibits antitumor activity against urothelial carcinoma and solid tumors. Dabogratinib downregulates the FGFR3 and ERK1/2 signaling pathways, and induces tumor growth inhibition and regression in FGFR3-altered xenograft models. Dabogratinib promotes chondrocyte proliferation and differentiation, drives endochondral bone formation and overall body growth, partially restores long bone proportions, and improves craniofacial and spinal morphology. Dabogratinib can be used for the research of metastatic urothelial carcinoma, achondroplasia and hypochondroplasia[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TYRA-300. CAS No. 2800223-30-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159642. | |
| Dabrafenib | Dabrafenib (GSK2118436A) is an ATP-competitive inhibitor of Raf with IC50s of 5 nM and 0.6 nM for C-Raf and B-RafV600E, respectively[4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GSK2118436A; GSK2118436. CAS No. 1195765-45-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-14660. | |
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