MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| DC661 | DC661 is a potent palmitoyl-protein thioesterase 1 (PPT1) inhibitor, inhibits autophagy, and acts as an anti-lysosomal agent. Anti-cancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1872387-43-3. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-111621. |  |
| DC_AC50 | DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones). Inhibiting intracellular copper chaperones as a means of reducing/preventing acquired chemotherapy resistance[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 497061-48-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-107636. | |
| DCAF15 ligand-1 | DCAF15 ligand-1 (compound 9) is a ligand for the E3 ligase DCAF15. DCAF15 ligand-1 can be used in the synthesis of IBG1 (HY-153459)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2098346-67-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-W037495. | |
| DCAF1 binder 1 | DCAF1 binder 1 is a selective for the CRL4 DCAF1 E3 ligase complex. DCAF1 binder 1 is a ligands for E3 Ligase, involving in targeted protein degradation (TPD)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3053860-67-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149934. | |
| DCAP | DCAP is a broad-spectrum antibiotic targeting the membranes of both Gram-positive and Gram-negative bacteria. DCAP blocks autophagy at the late stages by preventing autophagolysosome maturation and interrupting the autophagic flux[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VU0607402. CAS No. 500015-20-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-136068. | |
| D-Carnitine | D-Carnitine is an orally available isomer of the essential nutrient L-carnitine that promotes long-chain fatty acid transport into the mitochondrial matrix for beta-oxidation. D-Carnitine has antiparasitic activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 541-14-0. Pack Sizes: 10 mM * 1 mL in Water; 250 mg; 1 g. Product ID: HY-W012550. | |
| D-Cateslytin | D-Cateslytin is an antimicrobial peptide that exhibits potent inhibition activity against Candida albicans (MIC = 2.9 μM). D-Cateslytin can rapidly enter C. albicans, and shows no cytotoxicity to human gingival fibroblasts, and is stable in saliva. D-Cateslytin can be used for research on Candida albicans related diseases, such as oral candidosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3002053-77-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P11170. | |
| dCBP-1 | dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP based on Cereblon ligand. dCBP-1 is exceptionally potent at killing multiple myeloma cells and ablates oncogenic enhancer activity driving MYC expression[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2484739-25-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134582. | |
| DCC-3116 | DCC-3116 is an orally active ULK1/2 inhibitor. DCC-3116 can inhibit autophagy in lung cancer cells by inhibiting KRASG12C signaling, thereby inhibiting the proliferation of lung cancer cells and exerting anti-cancer effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2543673-19-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-160699. | |
| DC-Chol hydrochloride | DC-Chol hydrochloride is a cationic lipid. DC-Chol hydrochloride could inhibit Aβ40 fibril formation under appropriate experimental conditions. DC-Chol hydrochloride strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner. DC-Chol hydrochloride induces the production of Th1 (IL-2 and IFN-γ) and Th2 (IL-5) cytokines. DC-Chol hydrochloride can enhance the body's immune response to antigens. DC-Chol hydrochloride is used as a gene delivery vector. DC-Chol hydrochloride can be used in research in areas such as hepatitis B vaccines to improve vaccine immunity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DC-Cholesterol hydrochloride. CAS No. 166023-21-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-137131. | |
| DCEBIO | DCEBIO is a small/medium conductance calcium-activated potassium (SKCa/IKCa) channel opener and primary neuron signal blocker. It hyperpolarizes the membrane potential of C2C12 myoblasts by activating IKCa channels, thereby promoting myogenic differentiation. The specific biological activity of DCEBIO is manifested in increased myotube formation, enhanced myosin heavy chain II protein levels and myogenin mRNA levels. DCEBIO can be applied in the field of muscle research, especially in muscle-related degenerative diseases such as sarcopenia[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 60563-36-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102052. | |
| D-(+)-Cellotriose | D-(+)-Cellotriose (Cellotriose) is an oligosaccharide, it is an intermediate in the enzyme hydrolysis of cellulose[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cellotriose. CAS No. 33404-34-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W14549. | |
| DCEM1 | DCEM1 binds to heat shock protein 60 (HSP60) and inhibits the interaction of HSP60 with ClpP, thereby blocking the mitochondrial unfolded protein response. DCEM1 inhibits β-catenin expression and ATP production in PC-3 and TKO cells. DCEM1 can be used in prostate cancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 878949-21-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-171616. | |
| dCeMM1 | dCeMM1 is a RBM39 glue degrader. dCeMM1 shows functions by re-directing the activity of the CRL4DCAF15 ligase. dCeMM1 decreases the expression of RBM39 levels in WT KBM7 cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 118719-16-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-W133627. | |
| dCeMM2 | dCeMM2 (Compound 2) is a molecular glue-type degrader that targets cyclin K. dCeMM2 induces ubiquitination and degradation of cyclin K by prompting an interaction of CDK12-cyclin K with a CRL4B ligase complex[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 296771-07-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144971. | |
| dCeMM4 | dCeMM4 (Compound 5) is a molecular glue degrader. dCeMM4 induces ubiquitination and degradation of cyclin K by prompting an interaction of CDK12-cyclin K with a CRL4B ligase complex[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1281683-44-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144977. | |
| DCG04 | DCG04 is a multivalent ligand for the mannose-6-phosphate receptor. DCG-04 is an activity-based probe for cysteine cathepsins, and can be used for labelling numerous cysteine cathepsins in cell and tissue lysates[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 314263-42-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-101779. | |
| DCG-IV | DCG-IV is a potent agonist of group II mGluRs with EC50s of 0.35 and 0.09 μM for mGlu2R and mGlu3R, reapectively. DCG-IV is also a competitive antagonist at group I (IC50: mGlu1R/5R=389/630 μM) and III receptors (IC50: mGlu4R/6R/7R/8R= 22.5/39.6/40.1/32 μM). DCG-IV has anticonvulsive and neuroprotective effects[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 147782-19-2. Pack Sizes: 1 mg. Product ID: HY-101335. | |
| DCIP sodium | DCIP sodium is a blue dye commonly used in various biochemical and biotechnological applications as an indicator of redox reactions. DCIP sodium has unique chemical properties that change color according to the oxidation state of the substance being tested. It is commonly used in enzyme assays, such as measuring the activity of succinate dehydrogenase, or in protein quantification methods, such as the Lowry assay. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dichlorophenylindophenol sodium; DCPIP sodium; Indochlorophenol sodium. CAS No. 620-45-1. Pack Sizes: 1 g; 5 g. Product ID: HY-D0018. | |
| dCK1α-2 | dCK1α-2 is an orally active CK1α molecular glue degrader that targets p53 pathway-related targets. dCK1α-2 exhibits anti-tumor efficacy in mouse models and can increase the expression of p53-related genes.[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LC-05-004. CAS No. 3085297-83-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169347. | |
| D-Cl-amidine hydrochloride | D-Cl-amidine hydrochloride is a potent and highly selective PAD1 inhibitor. D-Cl-amidine is well-torelated with no significant toxicity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2985338-61-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100574D. | |
| DC-LC3in-D5 | DC-LC3in-D5 acts as an autophagy inhibitor by attenuating LC3B lipidation. DC-LC3in-D5 binds with LC3B. DC-LC3in-D5 disrupts the LC3B-LBP2 interaction with an IC50 of 200 nM. DC-LC3in-D5 may contribute to anti-HCV or combination researchs in cancer through inhibiting autophagy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2868312-73-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141882. | |
| DCLK1-IN-1 | DCLK1-IN-1 is a selective, oral bioavailability in vivo-compatible chemical probe of the doublecortin like kinase 1 (DCLK1 kinase) domain. DCLK1-IN-1 inhibits DCLK1 and DCLK2 kinases (IC50: DCLK1=9.5/57.2 nM and DCLK2=31/103 nM in binding and kinase assay, respectively). DCLK1-IN-1 shows low toxicity, and can investigate DCLK1 biology and establish its role in cancer, like DCLK1+ pancreatic ductal adenocarcinoma (PDAC)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2222635-15-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135985. | |
| DCM-ONOO | DCM-ONOO is a near-infrared two-photon fluorescence probe specifically designed for real-time monitoring of the dynamic fluctuations of peroxynitrite (ONOO?) in epilepsy models. DCM-ONOO exhibits excellent optical properties, with a single photon excitation (Ex) of 520 nm; a single photon emission (Em) of 685 nm; a two-photon excitation of 820 nm; and a Stokes shift of 165 nm. When DCM-ONOO is combined with ONOO?, it shifts from 460 nm to 512 nm, and only generates a significant fluorescence response to ONOO?. DCM-ONOO has been successfully applied to rat epilepsy models[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2759816-87-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D2968. | |
| DCPIB | DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels (VRAC). DCPIB voltage-dependently activates potassium channels TREK1 and TRAAK, and inhibits TRESK, TASK1 and TASK3 (IC50s: 0.14, 0.95, 50.72 μM, respectively). DCPIB is also a selective blocker of swelling-induced chloride current (ICl,swell), with an IC50 of 4.1 μM. DCPIB is a useful tool for investigating structure-function studies of K2P channels[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 82749-70-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103371. | |
| DCTA monohydrate | DCTA monohydrate is an organic acid. DCTA refers to N,N,N',N' -tetraacetic acid, which has a strong chelating ability. DCTA monohydrate can be used as a chelating agent and coordination reagent for metal ions. DCTA monohydrate, for example, forms stable complexes with many metal ions, including calcium, magnesium and zinc. DCTA modified with ethylene glycol is selective to calcium ions in the presence of magnesium ions[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 125572-95-4. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 100 g. Product ID: HY-W013178. | |
| DCVJ | DCVJ (9-(2,2-Dicyanovinyl)julolidine), a molecular rotor and unique fluorescent dye, binds to tubulin and actin, and increases its fluorescence intensity drastically upon polymerization. DCVJ also binds to phospholipid bilayers and increases its fluorescence intensity. DCVJ can detect the kinetic process of degranulation of mast cells (Absorption/emission=489/505 nm)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 9-(2,2-Dicyanovinyl)julolidine. CAS No. 58293-56-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1425. | |
| D-Cycloserine | D-Cycloserine is an antibiotic which targets sequential bacterial cell wall peptidoglycan biosynthesis enzymes, with blood-brain barrier permeability. D-Cycloserine is a partial NMDA agonist that can improve cognitive functions. D-Cycloserine can be used for multidrug-resistant tuberculosis research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 68-41-7. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0030. | |
| DCZ0415 | DCZ0415, a potent TRIP13 inhibitor, impairs nonhomologous end joining repair and inhibits NF-κB activity. DCZ0415 induces anti-myeloma activity in vitro, in vivo, and in primary cells derived from drug-resistant myeloma patients[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2242470-43-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 1 g. Product ID: HY-130603. | |
| DCZ5418 | DCZ5418 is an inhibitor of TRIP13. DCZ5418 has anti-multiple myeloma activity in vitro and in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2883709-99-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157331. | |
| DD-03-156 | DD-03-156 is a potent and selective degrader of CDK17 and LIMK2. The selectivity and potency of DD-03-156 is exquisite and makes an advanced starting point for the development of a chemical probe for the degradation of CDK17 (Blue: VHL ligand (HY-112078), Black: linker HY-124380 (HY-124380)?Pink: BRAF inhibitor (HY-14660))[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S,R,S)-AHPC-Me-PEG2-dabrafenib. CAS No. 2769753-69-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137346. | |
| DD-03-171 | DD-03-171 is a PROTAC BTK degrader. DD-03-171 inhibits mantle cell lymphoma (MCL) cell proliferation (IC50 = 5.1 nM) and prolongs the survival of mice bearing a lymphoma PDX model by degrading BTK, IKFZ1, and IKFZ3. DD-03-171 also inhibits platelet function and thrombosis. (Pink: BTK ligand 9 (HY-168292); Black: linker (HY-28875); Blue: Thalidomide-NH-CH2-COOH (HY-131717))[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2366132-45-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122830. | |
| DD202-114 | DD202-114 is a potent and selective GLP1R agonist. DD202-114 inhibits hERG with an IC50 of 15.9 μM. DD202-114 exhibits strong CYP2C8 inhibition with an IC50 of 0.22 μM. DD202-114 promotes cAMP accumulation. DD202-114 reduces blood glucose levels and food intake. DD202-114 has the potential to be used in the study of type 2 diabetes mellitus (T2DM) and obesity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2886728-09-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-163996. | |
| DDAO | DDAO is a promising near-infrared (NIR) red fluorescent probewith tunable excitation wavelength (600-650nm) and longemission wavelength(λem=656nm). DDAO can de desiged for detection of the activities of different enzymes such asβ-galactosidase,sulfatase, proteinphosphatase2A,carboxylesterase 2, humanalbumin andesterases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 118290-05-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114879. | |
| ddATP trisodium solution (100 mM) | ddATP (2',3'-Dideoxyadenosine 5'-triphosphate) trisodium, an active metabolite of 2',3'-dideoxyinosine, is a chain-elongating inhibitor of DNA polymerase. ddATP trisodium can be used for Sanger method for DNA sequencing and research of virus infection[1][2][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2',3'-Dideoxyadenosine 5'-triphosphate trisodium. CAS No. 72029-21-1. Pack Sizes: 100 μL; 200 μL; 500 μL; 1 mL. Product ID: HY-128036B. | |
| DDD85646 | DDD85646 (IMP-366) is an orally active of trypanosoma brucei N-myristoyltransferase (TbNMT IC50=2 nM; hNMT IC50=4 nM). The enzyme N-myristoyltransferase (NMT) is a potential agent target for human African trypanosomiasis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMP-366. CAS No. 1215010-55-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103056. | |
| Dde Biotin-PEG4-azide | Dde Biotin-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Dde Biotin-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1802907-93-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-140916. | |
| D-Desthiobiotin | D-Desthiobiotin is a biotin derivative. D-Desthiobiotin increases testosterone. D-Desthiobiotin is used in affinity chromatography and protein chromatography, also can be used for protein and cell labeling, detection and isolation[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dethiobiotin. CAS No. 533-48-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-128699. | |
| DDL-357 | DDL-357 is a potent secreted clusterin enhancer. DDL-357 reduces phospho-tau in brain and improves memory in the murine 3xTg-AD model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3077900-08-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-176438. | |
| DDMS | DDMS (Dibromo-dodecenyl-methylsulfimide) is a selective 20-HETE production inhibitor. DDMS attenuates the vasodilatory response to sodium nitroprusside (SNP)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dibromo-dodecenyl-methylsulfimide. CAS No. 206052-03-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121188. | |
| DDO-2213 | DDO-2213 is an orally active and potent WDR5-MLL1 inhibitor, with an IC50 of 29 nM and a Kd value of 72.9 nM for the WDR5 protein. DDO-2213 selectively inhibits MLL (mixed lineage leukemia) histone methyltransferase activity and the proliferation of MLL translocation-harboring cells. DDO-2213 can be used for MLL fusion leukemia research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2378768-36-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153331. | |
| DDO-2728 | DDO-2728 (compound 19) is a selective AlkB homologue 5 (ALKBH5) inhibitor with an IC50 of 2.97 μM. DDO-2728 increases the abundance of N6 methyladenosine (m6A) modifications, inducing cell apoptosis and cycle arrest. DDO-2728 suppresses tumor growth in the MV4 11 xenograft model with favorable safety profile, shows the potential of targeting ALKBH5 in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3029515-97-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155489. | |
| DDO-5936 | DDO-5936 is a potent and specific Hsp90-Cdc37 PPI inhibitor. DDO-5936 can be used for the research of colorectal cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2355377-13-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139301. | |
| DDR1-IN-1 | DDR1-IN-1 is a potent and selective DDR1 receptor tyrosine kinase inhibitor with an IC50 of 105 nM; 4-fold less potent for DDR2 (IC50 = 413 nM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1449685-96-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13979. | |
| DDR1-IN-4 | DDR1-IN-4 (Compound 2.45) is a selective and potent Discoidin Domain Receptor 1 (DDR1) autophosphorylation inhibitor, with IC50 values of 29 nM and 1.9 μM for DDR1 and DDR2, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2125676-13-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114173. | |
| DDR1-IN-6 | DDR1-IN-6 is a selective Discoidin Domain Receptor family, member 1 (DDR1) inhibitor with an IC50 of 9.72 nM. DDR1-IN-6 inhibits auto-phosphorylation DDR1b (Y513) with an IC50 of 9.7 nM. DDR1-IN-6 has anti-cancer activity[1]. DDR1-IN-6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2416021-47-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133670. | |
| DDR2-IN-1 | DDR2-IN-1 is potent DDR2 inhibitor with an IC50 of 26 nM. DDR2-IN-1, compound 129, can be used for osteoarthritis research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1573053-23-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112545. | |
| DDX3-IN-2 | DDX3-IN-2 is an active DEADbox polypeptide 3 (DDX3) inhibitor with an IC50 value of 0.3 μM. DDX3-IN-2 shows a broad spectrum of antiviral activity. DDX3-IN-2 has the potential to overcome HIV resistance[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1919828-81-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121969. | |
| Deacetylasperulosidic Acid | Deacetylasperulosidic Acid is an orally active antioxidant. Deacetylasperulosidic Acid exerts a definite in vivo antioxidant effect and alleviates oxidative stress injury by enhancing SOD activity. In atopic dermatitis models, Deacetylasperulosidic Acid corrects Th2-skewed immune imbalance and reduces allergy-related factors; in immunosuppression models, it activates cellular immunity, enhances NK cell activity and IL-2 production. Deacetylasperulosidic Acid can be used in the research of atopic dermatitis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 14259-55-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-N0594. | |
| Deacylketoconazole | Deacylketoconazole (N-Deacetylketoconazole; R-39519) is an orally active metabolite of Ketoconazole (HY-B0105). Deacylketoconazole exhibits antifungal and antibacterial activity. Deacylketoconazole is cytotoxic in rats hepatocyte[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Deacetylketoconazole; R-39519. CAS No. 67914-61-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129315. | |
| DEAE-Cellulose | DEAE-Cellulose (Diethylaminoethyl cellulose), a common biopolymer derivative. DEAE-Cellulose is a weakly basic cellulose anion exchanger[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Diethylaminoethyl cellulose. CAS No. 9013-34-7. Pack Sizes: 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W046325. | |
| DEAE-dextran, MW 500000 hydrochloride | DEAE-dextran, MW 500000 hydrochloride (DEAE-dextran, MW 500000 hydrochloride, from bacterial (Leuconostoc mesenteroides)) is a high-molecular-weight positively charged polymer that significantly enhances the uptake of viral RNA by tissue culture cells. When employed in the delivery system for "tumor immunity" RNA-splenocyte transfer, DEAE-dextran can markedly extend the lifespan of tumor-bearing animals, comparable to that of actively immunized animals. Furthermore, DEAE-dextran serves as a complexing agent for nucleic acids, forming composite particles with DNA/RNA for extensive applications in gene delivery. Additionally, DEAE-dextran can be utilized as a coating for liposomes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DEAE-dextran, MW 500000 hydrochloride, from bacterial (Leuconostoc mesenteroides); Diethylaminoethyl-dextran, MW 500000 hydrochloride. CAS No. 9064-91-9. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-159067. | |
| Deapi-platycodin D3 | Deapi-platycodin D3 is a triterpenoid saponin from the roots of Platycodon grandiflorum[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 67884-05-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N3520. | |
| Debio 0932 | Debio 0932 (CUDC-305) is an orally active HSP90 inhibitor, with IC50s of 100 and 103 nM for HSP90α and HSP90β, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CUDC-305. CAS No. 1061318-81-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13469. | |
| Debrisoquin hemisulfate | Debrisoquin (Isocaramidine) hemisulfate is a TMPRSS2 inhibitors that inhibits SARS-CoV-2 entry into human lung cell line by a TMPRSS2-depedent manner, with an IC50 of 22μM. Debrisoquin hemisulfate can be used for antiviral research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Debrisoquine hemisulfate; Isocaramidine hemisulfate; Ro 5-3307/1 hemisulfate. CAS No. 581-88-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1624A. | |
| Decaethylene glycol | Decaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HO-PEG10-OH. CAS No. 5579-66-8. Pack Sizes: 1 g; 5 g. Product ID: HY-141232. | |
| Decanoic acid | Decanoic acid is a key component of the medium-chain triglyceride (MCT) found in coconut oil. Decanoic acid is a brain-penetrant and non-competitive inhibitor of AMPA receptor showing antiseizure activity in rats. Decanoic acid reduces tyrosinase activity and inhibits melanosome maturation. Decanoic acid suppresses the phosphorylation of c-Met and induced apoptosis in hepatocellular carcinoma (HCC) cells by inhibiting the expression of various oncogenic proteins, which is promising for research in the field of mTORC1 signaling, HCC and epilepsy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 334-48-5. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-W015309. | |
| Decanoic acid sodium | Decanoic acid sodium, also known as Decanoic acid sodium, is a salt of the fatty acid capric acid. It is easily soluble in water and has a slightly soapy smell. Decanoic acid sodium acts as a penetration enhancer, which means it increases the absorption and bioavailability of drugs across biological membranes, including the intestinal epithelium and the blood-brain barrier. This property makes it useful in pharmaceutical formulations to improve drug delivery and effectiveness. Furthermore, Decanoic acid sodium has potential applications in food preservatives and cosmetics due to its antibacterial properties. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sodium decanoate; Sodium caprate. CAS No. 1002-62-6. Pack Sizes: 10 mM * 1 mL in Water; 5 g; 25 g. Product ID: HY-115340. | |
| Decanoylcarnitine | Decanoylcarnitine is a fatty ester lipid and an acylcarnitine derivative, which is a metabolite associated with impaired fatty acid metabolism in the elderly population[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1492-27-9. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-113069. | |
| Decanoyl coenzyme A | Decanoyl coenzyme A (Decanoyl CoA) is a primer for the fatty acid elongation system in Mycobacterium smegmat[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Decanoyl-coa. CAS No. 1264-57-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-137868. | |
| Decanoyl-L-carnitine-d3 chloride | Decanoyl-L-carnitine-d3 (chloride) is the deuterium labeled Decanoyl-L-carnitine chloride[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2483831-87-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-132949S. | |
| Decanoyl-RVKR-CMK | Decanoyl-RVKR-CMK (DecRVKRcmk) inhibits over-expressed gp160 processing and HIV-1 replication[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DecRVKRcmk. CAS No. 150113-99-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-107760. | |
| Decapeptide-12 | Decapeptide-12, a small oligopeptide, is a tyrosinase inhibitor that interacts with C-terminal residue of tyrosinase (Kd: 61.1 μM). Decapeptide-12 is a competitive inhibitor of mushroom tyrosinase (IC50: 40 μM). Decapeptide-12 also increases transcription of SIRT. Decapeptide-12 reduces melanin content in melanocytes. Decapeptide-12 is used for the research of melanogenesis, senescence, inflammation [1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 137665-91-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0096. | |
| Decernotinib | Decernotinib is a potent, orally active JAK3 inhibitor, with Kis of 2.5, 11, 13 and 11 nM for JAK3, JAK1, JAK2, and TYK2, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VX-509; VRT-831509. CAS No. 944842-54-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12469. | |
| Decitabine | Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-Aza-2'-deoxycytidine; 5-AZA-CdR; NSC 127716. CAS No. 2353-33-5. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg; 1 g; 2 g. Product ID: HY-A0004. | |
| Decitabine (Standard) | Decitabine (Standard) is the analytical standard of Decitabine. This product is intended for research and analytical applications. Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-Aza-2'-deoxycytidine (Standard); 5-AZA-CdR (Standard); NSC 127716 (Standard). CAS No. 2353-33-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0004R. | |
| Decoglurant | Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3. Decoglurant is developed as an antidepressant[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RO4995819. CAS No. 911115-16-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16766. | |
| Decoyinine | Decoyinine is a selective inhibitor of GMP synthetase (GMPS). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Angustmycin A. CAS No. 2004-4-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-101835. | |
| Decursin | Decursin ((+)-Decursin) is a potent anti-tumor agent. Decursin also is a cytotoxic agent and a potent protein kinase C activator. Decursin induces apoptosis and cell cycle arrest at G1 phase. Decursin decreases the expression of CDK2, CDK4, CDK6, cyclin D1 protein at 48 h. Decursin inhibits cell proliferation and migration. Decursin shows anti-tumor, anti-inflammatory and analgesic activities[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-Decursin. CAS No. 5928-25-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18981. | |
| (-)-Decursinol | (-)-Decursinol (Aegelinol; (-)-Smyrinol) is a natural pyranocoumarin compound tant can be isolated from the roots of Apiaceae plants such as Ferulago campestris. (-)-Decursinol inhibits both Gram-positive bacteria (Staphylococcus aureus ATCC 13709, Enterococcus faecalis ATCC 14428) and Gram-negative bacteria (Salmonella typhii ATCC 19430, Enterobacter cloacae ATCC 10699, Enterobacter aerogenes ATCC 13048) with minimum inhibitory concentrations (MIC) ranging from 16 to 64 μg/mL. (-)-Decursinol possesses antioxidant activity. (-)-Decursinol can be used for the study of bacterial infections[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Aegelinol; (-)-Smyrinol. CAS No. 21860-31-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W923644. | |
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