MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Demethylsuberosin | Demethylsuberosin (7-Demethylsuberosin) is a coumarin compound found in Angelica gigas Nakai. Demethylsuberosin exerts antihypertensive effects by inhibiting the L-type CaV1.2 channel. Demethylsuberosin has antioxidant and anti-inflammatory activities. Demethylsuberosin also exhibits neuroprotective activities against glutamate-induced toxicity in primary cultured rat cortical cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 7-Demethylsuberosin. CAS No. 21422-04-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg. Product ID: HY-N2488. |  |
| Demethylwedelolactone | Demethylwedelolactone is a naturally occurring coumestan isolated from Eclipta alba. Demethylwedelolactone is a potent trypsin inhibitor with an IC50 of 3.0 μM. Demethylwedelolactone suppresses cell motility and cell invasion of breast cancer cell[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6468-55-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2028. | |
| Demethylzeylasteral | Demethylzeylasteral is an orally active triterpenoid compound isolated from Tripterygium wilfordii, which has functions such as anti-inflammatory, anti-tumor, anti fertility, estrogen metabolism regulation, immune suppression, and immune system regulation [1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 107316-88-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg. Product ID: HY-N0587. | |
| Demoxytocin | Demoxytocin is a heterologous cyclic peptide and an analog of Oxytocin (HY-17571). Demoxytocin affects the permeability of cell membranes and increases calcium ion levels in smooth muscle cells, thereby enhancing the contraction of smooth muscle cells. Demoxytocin also stimulates the contraction of uterine smooth muscle. Demoxytocin possesses the functions of oxytocin. Demoxytocin can be used to study labor stimulation in preterm premature rupture of membranes[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 113-78-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2168. | |
| Dencatistat | Dencatistat is a CTP synthetase 1 (b | |
| Dencichine | Dencichin is a non-protein amino acid originally extracted from Panax notoginseng, and can inhibit HIF-prolyl hydroxylase-2 (PHD-2) activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dencichin; ODAP. CAS No. 5302-45-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-N1477. | |
| Denecimig | Denecimig (Mim8) is a factor VIII-mimetic bispecific antibody with micromolar human binding affinity for Factor X and Factor IXa. Denecimig binds Factor X and Factor IXa, localizes both to the phospholipid surface, enhances the Factor IXa-mediated activation of Factor X to Factor Xa, and stimulates the proteolytic activity of Factor IXa via its monovalent anti-Factor IXa arm. Denecimig is applicable to research related to hemophilia A[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mim8. CAS No. 2488745-86-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990060. | |
| Denifanstat | Denifanstat (TVB-2640) is an orally active and potent Fatty Acid Synthase (FASN) inhibitor with an IC50 of 0.052 μM and an EC50 of 0.072 μM. Denifanstat has the potential for fatty liver disease and cancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TVB-2640; FASN-IN-2; ASC-40. CAS No. 1399177-37-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112829. | |
| Denikitug | Denikitug (GS-1811; JTX-1811) is a humanized monoclonal antibody against CCR8 receptor with a KD of 16.8 pM. Denikitug specifically binds to human CCR8, inhibits CCL1-induced downstream CCR8 signaling. Denikitug selectively depletes cells expressing CCR8 via antibody-dependent cellular cytotoxicity (ADCC). Denikitug promotes anti-tumor immunity and can be used for the research of cancer and immunology[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS-1811; JTX-1811. CAS No. 2865822-82-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990914. | |
| Denopamine | Denopamine ((R)-(-)-Denopamine) is an orally active, selective β1-adrenergic agonist. Denopamine prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: suppression of tumor necrosis factor-α production in the heart. Cardiovascular effects[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-(-)-Denopamine; TA-064. CAS No. 71771-90-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119515. | |
| Denosumab | Denosumab is a human monoclonal antibody that targets the protein RANKL. Denosumab binds to the receptor activator of nuclear factor kappa-B ligand (RANKL) and prevents its binding to the RANK receptor (KD of 0.003 nM for human RANKL). Denosumab promotes proliferation and spermatogenesis. Denosumab prevents bone resorption through inhibition of the NF-κB pathway. Denosumab can be used in bone-related studies[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMG-162. CAS No. 615258-40-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9958. | |
| Denosumab (anti-TNFSF11) | Denosumab (anti-TNFSF11) is a human monoclonal antibody that targets the protein RANKL. Denosumab binds to the receptor activator of nuclear factor kappa-B ligand (RANKL) and prevents its binding to the RANK receptor (KD of 0.003 nM for human RANKL). Denosumab promotes proliferation and spermatogenesis. Denosumab prevents bone resorption through inhibition of the NF-κB pathway. Denosumab can be used in bone-related studies[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. CAS No. 615258-40-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9958A. | |
| Deoxycholic acid | Deoxycholic acid (cholanoic acid), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cholanoic acid; Desoxycholic acid. CAS No. 83-44-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-N0593. | |
| Deoxycholic acid-d4 | Deoxycholic acid-d4 is the deuterium labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity. Uses: Scientific research. Category: Signaling pathways. CAS No. 112076-61-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N0593S. | |
| Deoxycholic acid-d5 | Deoxycholic acid-d5 is the deuterium labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity. Uses: Scientific research. Category: Signaling pathways. CAS No. 52840-14-9. Pack Sizes: 2.5 mg. Product ID: HY-N0593S1. | |
| Deoxycholic acid-d6 | Deoxycholic acid-d6 is the deuterium labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cholanoic acid-d6; Desoxycholic acid-d6. CAS No. 2483832-09-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0593S2. | |
| Deoxycholic acid sodium salt | Deoxycholic acid sodium salt (sodium deoxycholate), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sodium deoxycholate. CAS No. 302-95-4. Pack Sizes: 100 mg; 500 mg. Product ID: HY-N0593A. | |
| Deoxycorticosterone | Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor. Deoxycorticosterone is an agonist for O. mykiss mineralocorticoid receptor (rtMR) transcription with EC50 of 0.16 nM[3]. Deoxycorticosterone could acts as an immune stimulator in fish[4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 64-85-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-113414. | |
| Deoxycorticosterone acetate | Deoxycorticosterone acetate (DOCA) is an adrenocortin, acts as a precursor to aldosterone. Deoxycorticosterone acetate is a mineralocorticoid receptor agonist. Deoxycorticosterone acetate can cause severe renal injury, including inflammation, fibrosis, glomerular damage, and proteinuria[1][2]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: 11-Deoxycorticosterone acetate; DOC acetate; Cortexone acetate. CAS No. 56-47-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B1472. | |
| Deoxycorticosterone-d8 | Deoxycorticosterone-d8 is the deuterium labeled Deoxycorticosterone. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 55487-63-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-113414S. | |
| Deoxycorticosterone (Standard) | Deoxycorticosterone (Standard) is the analytical standard of Deoxycorticosterone. This product is intended for research and analytical applications. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor. Uses: Scientific research. Category: Signaling pathways. CAS No. 64-85-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113414R. | |
| Deoxyelephantopin | Deoxyelephantopin, a natural bioactive sesquiterpene lactone from Elephantopus scaber, has shown promising anticancer effects against a broad spectrum of cancers. Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 29307-03-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-N2491. | |
| Deoxygeraniol | Deoxygeraniol, a monoterpenoid, has been reported in Camellia sinensis, Magnolia sieboldii, and Zingiber officinale. It is commonly used as an intermediate in the synthesis of fragrances or flavorings. Uses: Scientific research. Category: Signaling pathways. CAS No. 2609-23-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W711045. | |
| Deoxyguanosine triphosphate trisodium solution (100 mM) | Deoxyguanosine triphosphate (dGTP) trisodium solution (100 mM) is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: dGTP trisodium solution (100 mM); 2'-Deoxyguanosine-5'-triphosphate trisodium solution (100 mM). CAS No. 93919-41-6. Pack Sizes: 28.66 mg (100 mM * 500 μL in Water); 57.31 mg (100 mM * 1 mL in Water). Product ID: HY-W008661. | |
| Deoxynivalenol | Deoxynivalenol, an orally active mycotoxin of the trichothecenes family, crosses the intestinal mucosa by a paracellular pathway through the tight junctions. The Deoxynivalenol transport is not affected by P-glycoprotein (PgP) or multidrug resistance-associated proteins (MRPs) inhibitors[1]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Vomitoxin. CAS No. 51481-10-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N6684. | |
| Deoxyribonuclease II | Deoxyribonuclease II (DNase II) is an endonuclease that hydrolyzes the phosphodiester bonds of deoxyribonucleotides in native and denatured DNA, producing 3' phosphate and 5'-hydroxyl termini. Deoxyribonuclease II works best at acidic pH and is commonly used in biochemical research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DNase II. CAS No. 9025-64-3. Pack Sizes: 5 KU; 40 KU. Product ID: HY-P2863. | |
| Deoxyribonucleic acid sodium, from calf thymus, Type I, fibers | Deoxyribonucleic acid sodium, from calf thymus, Type I, fibers is the sodium salts form of Calf thymus DNA (HY-109517). Calf thymus DNA is a double-stranded template DNA isolated from calf thymus. It can be used to study the interaction between DNA and DNA binding agents, as well as the structure and function of DNA, for DNA quantification and used as a substrate for DNA polymerase analysis, etc?[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ctDNA sodium, Type I, fibers; DNA sodium, from calf thymus, Type I, fibers; Thymonucleic acid sodium, Type I, fibers. CAS No. 73049-39-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153118. | |
| Deoxyribonucleic acid sodium salt from salmon testes | Deoxyribonucleic acid sodium salt from salmon testes (ssstDNA) can be used to make anti-adhesion layers (AALs) for passivating gold plasmonic sensor surfaces[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SS-DNA. CAS No. 438545-06-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-172445. | |
| Deoxyshikonin | Deoxyshikonin increases the expression of VEGF-C and VEGF-A mRNA in HMVEC-dLy, promotes HIF-1α and HIF-1β subunit interaction and binds to specific DNA sequences targeted by HIF. Deoxyshikonin inhibited colorectal cancer (CRC) through the PI3K/Akt/mTOR pathway. Deoxyshikonin has proangiogenesis effect and antitumor activity. Deoxyshikonin is an antibacterial agent against methicillin-resistant S. aureus (MRSA) and S. pneumonia (MIC=17 μg/mL)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 43043-74-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg. Product ID: HY-N2187. | |
| Deoxytopsentin | Deoxytopsentin (compound 5) is a marine bisindole alkaloid and also a MRSA pyruvate kinase inhibitor. Deoxytopsentin exists in sponges. Deoxytopsentin exhibits antibacterial activity against methicillin-resistant Staphylococcus aureus strains in vitro[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 112515-42-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N15451. | |
| Deoxyvasicinone | Deoxyvasicinone is an alkaloid compound isolated from plants[1]. Uses: Scientific research. Category: Natural products. Alternative Names: 9-Oxodeoxypeganine; Pegenone. CAS No. 530-53-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N3735. | |
| Depatuxizumab | Depatuxizumab is a brain-penetrant and humanized tumor-specific anti EGFR monoclonal antibody. Depatuxizumab inhibits the growth of xenograft models of mutant EGFRvIII and wild-type EGFR. Depatuxizumab can be used for research on cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABT-806. CAS No. 1471999-69-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99849. | |
| Depatuxizumab mafodotin | Depatuxizumab mafodotin (ABT-414) is an antibody-drug conjugate (ADC). Depatuxizumab mafodotin specifically targets the epidermal growth factor receptor (EGFR). Depatuxizumab mafodotin can be used in the study of glioma, head and neck squamous cell carcinoma, non-small cell lung cancer, epidermoid carcinoma of the skin, and squamous cell carcinoma of the tongue[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABT-414. CAS No. 1585973-65-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132259. | |
| Depemokimab | Depemokimab (GSK-3511294) is a long-acting anti-IL-5 monoclonal antibody. Depemokimab can be used for research of asthma[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GSK-3511294. CAS No. 2243274-14-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99850. | |
| Dephospho-CoA | Dephospho-CoA is a key intermediate in the biosynthesis of coenzyme A (CoA), which is catalyzed to form CoA by GTP-dependent Dephospho-CoA kinase (DPCK). Dephospho-CoA completes the final synthetic step of CoA via phosphorylation and participates in energy metabolism and cellular signal transduction. Dephospho-CoA can be used in studies involving cancer (e.g., regulation of cell proliferation) and metabolic diseases (e.g., mitochondrial dysfunction)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3633-59-8. Pack Sizes: 5 mg. Product ID: HY-137899. | |
| DEPMPO | cDEPMPO is a potent anticancer proagent. High concentrations of DEPMPO spin-trap the ·OH radical together with aryl radicals arising from one-electron reduced BTO (benzotriazine 1,4-di-N-oxide) compounds[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 157230-67-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120976. | |
| Dequalinium Chloride | Dequalinium chloride is an Apamin (HY-P0256)-sensitive potassium channel selective blocker. Dequalinium chloride is a cationic, lipophilic mitochondrial poison. Dequalinium chloride is also an antagonist pf α7 nAChR, and an anti-microbial antiseptic agent with a broad bactericidal and fungicidal activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 522-51-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0567. | |
| Derazantinib | Derazantinib (ARQ-087) is an ATP competitive and orally activeFGFR inhibitor (IC50s: 1.8 nM for FGFR2, 4.5 nM for FGFR1 and 3 nM). Derazantinib inhibits FGFR phosphorylation. Derazantinib inhibits tumor growth in multiple xenograft models[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ARQ-087. CAS No. 1234356-69-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19981. | |
| Derenofylline | Derenofylline (SLV 320) is a potent, selective and orally active adenosine A1 receptor antagonist, with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively. Derenofylline suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SLV 320. CAS No. 251945-92-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14858. | |
| Dermaseptin | Dermaseptin, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 136212-91-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0263. | |
| Dermatan sulphate sodium | Dermatan sulphate sodium is an oral active glycosaminoglycan and thrombin inactivator with antithrombotic activity. It selectively catalyzes the heparin cofactor II-mediated inactivation of thrombin without interacting with antithrombin III. Dermatan sulphate sodium promotes stem cell differentiation, exhibits high bioavailability, and alleviates pulmonary fibrosis injury induced by Bleomycin (HY-108345). Dermatan sulphate sodium can be used in research related to cardiovascular diseases, inflammation, and stem cell differentiation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 54328-33-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N8278. | |
| Dermorphin | Dermorphin is a natural heptapeptide μ-opioid receptor (MOR) agonist found in amphibian skin. Inhibition of neuropathic pain[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 77614-16-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P0244. | |
| Derquantel | Derquantel, a spirocyclic anthelmintic, is a competitive, orally active nicotinic acetylcholine receptor (nAChR) antagonist. Derquantel inhibits ACh-induced depolarization with an IC50 of 0.22 μM. By selectively antagonizing nAChRs on the somatic muscles of nematodes, Derquantel causes flaccid paralysis of muscles, thereby dislodging parasites from the host's gastrointestinal tract. Derquantel is applicable to research related to Haemonchus contortus infection and Ascaris suum infection[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-00520904. CAS No. 187865-22-1. Pack Sizes: 5 mg. Product ID: HY-125159. | |
| Dersimelagon | Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist with EC50 values of 8.16, 3.91, 1.14 and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m) and rat (r) MC1R, respectively. Dersimelagon shows good affinity for hMC1R and hMC4R with Ki values of 2.26, 32.9 nM, respectively. Dersimelagon can be used for the research of skin pigmentation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MT-7117. CAS No. 1835256-48-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-109114. | |
| Deruxtecan | Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MC-GGFG-DXD. CAS No. 1599440-13-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13631E. | |
| Deruxtecan 2-hydroxypropanamide | Deruxtecan 2-hydroxypropanamide is a highly stable Deruxtecan (HY-13631E) analog that specifically binds to receptors highly expressed in tumor cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2577204-16-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153891. | |
| Deruxtecan analog 2 | Deruxtecan analog 2 (example 9 P3) is a Deruxtecan (HY-13631E) analog. Deruxtecan analog 2 is a agent-linker conjugate composed of Camptothecin (HY-16560) and a linker. Camptothecin (CPT) is a Topo I inhibitor with antineoplastic activity against colorectal, breast, lung and ovarian cancers. Deruxtecan analog 2 can be used for the preparation anti-FGFR2 ADC[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1599440-10-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128979. | |
| Deruxtecan (GMP) | Deruxtecan (GMP) (MC-GGFG-DXD (GMP)) is Deruxtecan (HY-13631E) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MC-GGFG-DXD (GMP). CAS No. 1599440-13-7. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-13631EG. | |
| D-Erythro-dihydrosphingosine | D-Erythro-dihydrosphingosin directly inhibits cytosolic phospholipase A2α (cPLA2α) activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sphinganine (d18:0). CAS No. 764-22-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W019838. | |
| D-Erythrose 4-phosphate sodium | D-Erythrose 4-phosphate sodium is a phosphate sodium of the simple sugar Erythrose. Erythritol is actually converted into D-Erythrose 4-phosphate that involves three isomerases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 103302-15-4. Pack Sizes: 1 mg. Product ID: HY-N7386A. | |
| D-Erythrose (50% in water) | D-Erythrose is a four-carbon sugar classified as an aldose. D-Erythrose has unique chemical properties that make it an important intermediate in various metabolic pathways, especially in the biosynthesis of amino acids and nucleotides. It also plays a role in the pentose phosphate pathway, which generates reducing equivalents for biosynthetic reactions and cellular defense against oxidative damage. Uses: Scientific research. Category: Signaling pathways. CAS No. 583-50-6. Pack Sizes: 100 mg; 250 mg. Product ID: HY-116956. | |
| D-erythro-Sphingosine | D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Erythrosphingosine; erythro-C18-Sphingosine; trans-4-Sphingenine. CAS No. 123-78-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-101047. | |
| D-erythro-Sphingosine-d7 | D-erythro-Sphingosine-d7 is the deuterium labeled D-erythro-Sphingosine. D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Erythrosphingosine-d7; erythro-C18-Sphingosine-d7; trans-4-Sphingenine-d7. CAS No. 1246304-34-6. Pack Sizes: 500 μg. Product ID: HY-101047S. | |
| Desacetyl bisacodyl | Desacetyl bisacodyl is the active metabolite of the laxative bisacodyl. Desacetyl bisacodyl induces epithelial Cl(-) secretion in rat colon and rectum. Desacetyl bisacodyl evokes several effects at the colon or rectum, including increased mucus and chloride secretion[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 603-41-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131637. | |
| Desamino lenalidomide-CH2NH2 hydrochloride | Desamino lenalidomide-CH2NH2 hydrochloride is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-CH2NH2 hydrochloride can be linked to a target protein ligand via a linker to form a PROTAC. Uses: Scientific research. Category: Signaling pathways. CAS No. 2248702-12-5. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W584677. | |
| Desamino lenalidomide-pinacolborane | Desamino lenalidomide-pinacolborane is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-pinacolborane can be linked to a target protein ligand via a linker to form a PROTAC. Uses: Scientific research. Category: Signaling pathways. CAS No. 2291363-98-7. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W244728. | |
| Desamino lenalidomide-Pip hydrochloride | Desamino lenalidomide-Pip hydrochloride is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC. Uses: Scientific research. Category: Signaling pathways. CAS No. 2291360-60-4. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W594189. | |
| [Des-Arg9]-Bradykinin acetate | [Des-Arg9]-Bradykinin acetate is a Bradykinin B1 receptor agonist that displays selectivity for B1 over B2 receptors. Uses: Scientific research. Category: Signaling pathways. CAS No. 23827-91-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0298A. | |
| (Des-Asp1,Ile8)-Angiotensin II | (Des-Asp1,Ile8)-Angiotensin II is a peptide related to angiotensin II. (Des-Asp1,Ile8)-Angiotensin II can be used for studying the interaction between angiotensin II and its receptors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 52498-25-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P11363. | |
| Deschloroclozapine | Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist, with blood-brain barrier permeability. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively. [11C]-Deschloroclozapine is developed as a promising PET tracer for DREADD imaging[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1977-7-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-42110. | |
| Desfesoterodine | Desfesoterodine (PNU-200577) is a potent and selective muscarinic receptor (mAChR) antagonist with a KB and a pA2 of 0.84 nM and 9.14, respectively[1]. Desfesoterodine is a major pharmacologically active metabolite of Tolterodine (PNU-200583; HY-A0024) and Fesoterodine (HY-70053)[2][3]. Desfesoterodine improves cerebral infarction induced detrusor overactivity in rats[4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PNU-200577; 5-Hydroxymethyl Tolterodine. CAS No. 207679-81-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-76569. | |
| des-?Gln14-?Ghrelin | des-Gln14-Ghrelin is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca2+]i in CHO-GHSR62 cells, with an EC50 of 2.4 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 293735-04-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1366. | |
| (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH | (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (Surfagon, Mwt 1167.34 Da) is an agonist of gonadotropin-releasing hormone (GnRH). (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH can be used as an internal standard for the LC-MS analysis of leuprorelide acetate. (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH has potential applications in biochemical analysis and fertility[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Surfagon. CAS No. 52435-06-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0048. | |
| Desglymidodrine | Desglymidodrine (ST 1059), the active metabolite of Midodrine(HY-12749), is a selective α1-adrenoceptor agonist. Desglymidodrine is an effective arterial and venous vasoconstrictor and can be used to regulate blood pressure[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ST 1059. CAS No. 3600-87-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-114794. | |
| [Des-His1,Glu9]-Glucagon amide | [Des-His1,Glu9]-Glucagon amide is a potent and peptide antagonist of the glucagon receptor, with a pA2 of 7.2. [Des-His1,Glu9]-Glucagon amide is potentially useful in the study of the pathogenesis of diabetes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 110084-95-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1143. | |
| Deshydroxyethoxy ticagrelor | Deshydroxyethoxy ticagrelor (AR-C124910) is a metabolite of Ticagrelor (HY-10064) with antimicrobial and antiplatelet activities against MRSA[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AR-C124910. CAS No. 220347-05-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-78542. | |
| Desidustat | Desidustat is an orally active HIF hydroxylase inhibitor. Desidustat can be used for the research of various disorders including anemia of different types and conditions associated with ischemia/hypoxia[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZYAN1. CAS No. 1616690-16-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103227. | |
| Desipramine hydrochloride | Desipramine hydrochloride is a first-generation tricyclic antidepressant. Desipramine hydrochloride selectively binds to norepinephrine transporter and blocks neuronal norepinephrine reuptake. Desipramine hydrochloride activates MAPK signaling via ERK1/2, JNK, and p38, represses NF-κB and AP-1 activity, and induces apoptosis via ROS elevation, mitochondrial membrane potential reduction, and intracellular calcium increase. Desipramine hydrochloride also shows anyi-inflammatory activity, inhibiting TNF-α production. Desipramine hydrochloride can be used for the research of hepatocellular cancer, inflammation, and neurological diseases[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 58-28-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-B1272. | |
| Desisopropylatrazine-d5 | Desisopropylatrazine-d5 is the deuterium labeled Desisopropylatrazine[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1189961-78-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-146604S. | |
| Deslanoside | Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation. Deslanoside inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations [1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Deacetyllanatoside C; Desacetyllanatoside C. CAS No. 17598-65-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-A0154. | |
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