MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Dihydronicotinamide riboside | Dihydronicotinamide riboside is a potent NAD+ concentration enhancer. Dihydronicotinamide riboside modulates targets BAX, PUMA, NQO2, and IκB kinase. Dihydronicotinamide riboside mediates apoptosis, induces pro-oxidant activity, mitochondrial dysfunction, metabolic dysregulation, redox modulation, and pro-inflammatory M1 phenotype induction. Dihydronicotinamide riboside increases intracellular and mitochondrial NAD+ levels, maintains cell survival against NAD+-depleting genotoxins. Dihydronicotinamide riboside can be used for the research of hepatocellular carcinoma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 19132-12-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W614507. |  |
| Dihydrorhodamine 123 | Dihydrorhodamine 123 (DHR 123) is a non-fluorescent reactive oxygen species (ROS) indicator. Dihydrorhodamine 123 is oxidized to fluorescent Rhodamine 123 (HY-D0816) within cells in the presence of reactive oxygen species and it localizes in mitochondria (Ex/Em = 515/536 nm). Uses: Scientific research. Category: Signaling pathways. Alternative Names: DHR 123. CAS No. 109244-58-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-101894. | |
| Dihydrouracil | Dihydrouracil (5,6-Dihydrouracil), a metabolite of Uracil, can be used as a marker for identification of dihydropyrimidine dehydrogenase (DPD)-deficient[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5,6-Dihydrouracil. CAS No. 504-07-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W012926. | |
| Dihydrouracil-13C4,15N2 | Dihydrouracil-13C4,15N2 is the 13C and 15N labeled Dihydrouracil[1]. Dihydrouracil (5,6-Dihydrouracil), a metabolite of Uracil, can be used as a marker for identification of dihydropyrimidine dehydrogenase (DPD)-deficient[2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5,6-Dihydrouracil-13C4,15N2. CAS No. 360769-22-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W012926S. | |
| DiI | DiI is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DiIC18(3). CAS No. 41085-99-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0083. | |
| Dilaurylglycerosulfate sodium | Dilaurylglycerosulfate sodium is a co-emulsifier in the diagnostic test for the determination of lipase. Uses: Scientific research. Category: Signaling pathways. CAS No. 99388-09-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135996A. | |
| Dilazep dihydrochloride | Dilazep dihydrochloride is an inhibitor of adenosine uptake. Dilazep dihydrochloride has cerebral and coronary vasodilating action through enhancement of effect of adenosine. Dilazep dihydrochloride also inhibits the ischemic damage, platelet aggregation, and membrane transport of nucleosides[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 20153-98-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100957. | |
| Dilazep dihydrochloride (Standard) | Dilazep (dihydrochloride) (Standard) is the analytical standard of Dilazep (dihydrochloride). This product is intended for research and analytical applications. Dilazep dihydrochloride is an inhibitor of adenosine uptake. Dilazep dihydrochloride has cerebral and coronary vasodilating action through enhancement of effect of adenosine. Dilazep dihydrochloride also inhibits the ischemic damage, platelet aggregation, and membrane transport of nucleosides[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 20153-98-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100957R. | |
| D-Ile-Pro-Arg p-nitroanilide dihydrochloride | D-Ile-Pro-Arg p-nitroanilide dihydrochloride is a chromogenic peptide substrate of tissue plasminogen activator (tPA)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 96323-41-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-137837. | |
| Dilmapimod | Dilmapimod (SB-681323) is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SB-681323; GW 681323. CAS No. 444606-18-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10404. | |
| Diltiazem | Diltiazem is an orally active L-type Ca2+ channel blocker. Diltiazem shows antihypertensive and antiarrhythmic effects. Diltiazem can be used for the research of cardiac arrhythmia, hypertension, and angina pectoris[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 42399-41-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B0632. | |
| Diltiazem hydrochloride | Diltiazem hydrochloride is a Ca2+ influx inhibitor (slow channel blocker or calcium antagonist). Uses: Scientific research. Category: Signaling pathways. Alternative Names: CRD-401. CAS No. 33286-22-5. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g; 5 g. Product ID: HY-14656. | |
| DIM-3,5-Cl2 | DIM-3,5-Cl2 is an inverse NR4A1/NR4A2 agonist with KD values of 7.7 μM and 12.0 μM for NR4A1 and NR4A2, respectively. DIM-3,5-Cl2 acts as an inverse agonist to downregulate pro-oncogenic and proendometriotic gene products, and as an agonist to enhance NR4A1/2/Sp1/Sp4-mediated CD71 transactivation. DIM-3,5-Cl2 induces ferroptosis via ROS formation, lipoperoxidation, MDA production, and reduced GPX4, SLC7A11 expression. DIM-3,5-Cl2 induces apoptosis via PARP and caspase-3 cleavage, reduced BCL-2 expression, and inhibits cancer cell viability. DIM-3,5-Cl2 can be used for the research of triple negative breast cancer, endometriosis, and colorectal cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2595179-74-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-179528. | |
| Dimaprit dihydrochloride | Dimaprit dihydrochloride is a selective histamine H2 receptor agonist, it also inhibits nNOS with an IC50 of 49 μM. Dimaprit dihydrochloride can stimulate gastric acid secretion[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 23256-33-9. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-B1478. | |
| DIMBOA | DIMBOA, an antibiotic, has antibacterial properties and inhibits bacteria such as Staphylococcus aureus and the mycotoxin-producing fungus Fusarium graminearum (which causes scab). DIMBOA exhibits strong free radical scavenging activity and weak iron(III) ion reducing activity, and has antioxidant activity. DIMBOA inhibits the biosynthesis and accumulation of toxic trichothecenes by affecting the expression of Tri6 and Tri5. DIMBOA reduces plant susceptibility to scab. DIMBOA also exhibits cytotoxicity to plant cells, causing plasmolysis, cell collapse, and cell rupture[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 15893-52-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N7432. | |
| DIMBOA (Standard) | DIMBOA (Standard) is the analytical standard of DIMBOA. This product is intended for research and analytical applications. DIMBOA, an antibiotic, has antibacterial properties and inhibits bacteria such as Staphylococcus aureus and the mycotoxin-producing fungus Fusarium graminearum (which causes scab). DIMBOA exhibits strong free radical scavenging activity and weak iron(III) ion reducing activity, and has antioxidant activity. DIMBOA inhibits the biosynthesis and accumulation of toxic trichothecenes by affecting the expression of Tri6 and Tri5. DIMBOA reduces plant susceptibility to scab. DIMBOA also exhibits cytotoxicity to plant cells, causing plasmolysis, cell collapse, and cell rupture[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 15893-52-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N7432R. | |
| DIM-C-pPhCO2Me | DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1) antagonist. DIM-C-pPhCO2Me induces Apoptosis. DIM-C-pPhCO2Me decreases PAX3-FOXO1A, N-Myc, Rassf4, MyoD1, Grem1, and DAPK1 proteins. DIM-C-pPhCO2Me decreases expression of TXNDC5 and IDH1, induces markers of ER stress (CHOP, ATF4 and p-PERK). DIM-C-pPhCO2Me inhibits renal cell carcinoma, breast cancer. DIM-C-pPhCO2Me can also be used in rhabdomyosarcoma research[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 151358-48-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112056. | |
| DIM-C-pPhOH | DIM-C-pPhOH is a nuclear receptor 4A1 (NR4A1) antagonist. DIM-C-pPhOH inhibits cancer cell growth and mTOR signaling, induce apoptosis and cellular stress. DIM-C-pPhOH reduces cell proliferation with IC50 values of 13.6 μM and 13.0 μM for ACHN cells and 786-O cells, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 151358-47-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112055. | |
| Dimedone | Dimedone (5,5-Dimethylcyclohexane-1,3-dione) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5,5-Dimethylcyclohexane-1,3-dione. CAS No. 126-81-8. Pack Sizes: 10 mM * 1 mL in DMSO; 50 g; 100 g; 250 g; 500 g; 1000 g. Product ID: HY-W015740. | |
| Dimenhydrinate | Dimenhydrinate is an orally active H1-antihistamine consisting of Diphenhydramine (HY-B0303) and 8-Chlorotheophylline. Dimenhydrinate is used to prevent nausea, vomiting, dizziness, and vertigo associated with motion sickness[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 523-87-5. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-B1215. | |
| Dimercaprol | Dimercaprol (2,3-Dimercapto-1-propanol) is an anti-heavy metal-poisoning agent, which exhibits anti-HIV activity. Dimercaprol can be used for the study for arsenic, mercury, gold, lead, antimony, and other toxic metal poisoning[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2,3-Dimercapto-1-propanol; Dithioglycerol. CAS No. 59-52-9. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-B1285. | |
| Dimethoate | Dimethoate is an organophosphate insecticide and acaricide. Dimethoate is an orally active acetylcholinesterase inhibitor. Dimethoate induces reactive oxygen species (ROS). Dimethoate induces DNA damage and cell apoptosis in vivo. Dimethoate affect immune system in mice[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 60-51-5. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-B1946. | |
| Dimethoate (Standard) | Dimethoate (Standard) is the analytical standard of Dimethoate. This product is intended for research and analytical applications. Dimethoate is an organophosphate insecticide and acaricide. Dimethoate is an orally active acetylcholinesterase inhibitor. Dimethoate induces reactive oxygen species (ROS). Dimethoate induces DNA damage and cell apoptosis in vivo. Dimethoate affect immune system in mice. Uses: Scientific research. Category: Signaling pathways. CAS No. 60-51-5. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B1946R. | |
| Dimethyl 2-oxoglutarate | Dimethyl 2-oxoglutarate (Dimethyl α-ketoglutarate) is a cell-permeable derivative of 2-oxoglutarate and tricarboxylic acid cycle metabolite with antioxidant properties. Dimethyl 2-oxoglutarate inhibits Autophagy. Dimethyl 2-oxoglutarate prevents mitochondrial damage and reduces ROS production. Dimethyl 2-oxoglutarate alleviates Carbon tetrachloride (HY-Y0298)-induced liver fibrosis. Dimethyl-2-oxoglutaric acid can be used in the research of diseases such as Alzheimer's disease, diabetes, and cardiomyopathy[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dimethyl α-ketoglutarate. CAS No. 13192-04-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g. Product ID: HY-44134. | |
| Dimethyl 2-oxoglutarate (Standard) | Felypressin (Standard) is the analytical standard of Felypressin. This product is intended for research and analytical applications. Felypressin (PLV-2) is a non-catecholamine vasoconstrictor and a vasopressin 1 agonist. Felypressin is widely used in dental procedures[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dimethyl α-ketoglutarate (Standard). CAS No. 13192-04-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-44134R. | |
| Dimethylamiloride | Dimethylamiloride is a specific antiporter inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1214-79-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg. Product ID: HY-138866. | |
| Dimethyl-bisphenol A | Dimethyl-bisphenol A (DMBPA) is a potent HIF-1α inhibitor. Dimethyl-bisphenol A can decrease Vegfa mRNA expression[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DMBPA. CAS No. 1568-83-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg. Product ID: HY-115746. | |
| Dimethyldioctadecylammonium bromide | Dimethyldioctadecylammonium bromide is a synthetic cationic lipid commonly used in gene delivery and vaccine development. Also known as DODAB or DDAB, it consists of a positively charged ammonium head group and two long hydrophobic tails. These properties make it useful for forming liposomes and other lipid-based nanoparticles that can efficiently deliver genetic material into cells. In addition to its applications in biotechnology, DDAB is also used in surfactants, emulsifiers and fabric softeners. However, due to its potential toxicity and irritation, extreme care should be taken when handling DDAB. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dioctadecyldimethylammonium bromide; DODAB. CAS No. 3700-67-2. Pack Sizes: 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-131119. | |
| Dimethylenastron | Dimethylenastron is a potent kinesin Eg5 inhibitor, with an IC50 of 200 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 863774-58-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19944. | |
| Dimethyl-F-OICR-9429-COOH | Dimethyl-F-OICR-9429-COOH a ligand for WD40 repeat domain protein 5 (WDR5) extracted from patent WO2019246570A1 intermediate 19. Dimethyl-F-OICR-9429-COOH can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2407458-49-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141799. | |
| Dimethyl fumarate | Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 624-49-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 5 g. Product ID: HY-17363. | |
| Dimethyl fumarate-d2 | Dimethyl fumarate-d2 is the deuterium labeled Dimethyl fumarate[1]. Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research[2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 23057-98-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-17363S1. | |
| Dimethyl isophthalate | Dimethyl isophthalate is a kind of biological materials or organic compounds that are widely used in life science research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1459-93-4. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 100 g; 500 g; 1 k g. Product ID: HY-W015028. | |
| Dimethyl itaconate | Dimethyl itaconate induces innate immune memory (trained immunity), and exhibits immunomodulatory property. Dimethyl itaconate inhibits the activation of microglia, reduces the neuroinflammation and synaptic structural damage. Dimethyl itaconate regulates the composition of intestinal flora[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 617-52-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 g. Product ID: HY-W041892. | |
| Dimethyl malonate | Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 108-59-8. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-Y1787. | |
| Dimethyl methylene blue zinc chloride double salt | Dimethyl methylene blue zinc chloride double salt (DMMB) is a cationic dye. Dimethyl methylene blue zinc chloride double salt competitively binds to the active site of the PANI-Benz-Ag nanocomposite with endotoxin, releasing DMMB and increasing the fluorescence intensity. Dimethyl methylene blue zinc chloride double salt can be used as a fluorescent probe for the detection of bacteria (such as E. Coli) endotoxin[1]. Dimethyl methylene blue zinc chloride double salt can be used for the quantification of sulfated glycosaminoglycans[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DMMB. CAS No. 931418-92-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W751238. | |
| Dimethyl silicone oil, viscosity 100 cSt (25 °C) | Dimethyl silicone oil, viscosity 100 cSt (25 °C) (Poly(dimethylsiloxane) (PDMS), viscosity 100 cSt (25 °C); Dimethylsilcone fluid, viscosity 100 cSt (25 °C)) is a transparent, colorless, and inert polydimethylsiloxane liquid with stable properties. Dimethyl silicone oil, viscosity 100 cSt (25 °C) exhibits high dielectric strength and excellent lubrication, cushioning, and thermal conductivity. Dimethyl silicone oil, viscosity 100 cSt (25 °C) can be used in cosmetics, lubricants, and electronics. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Poly(dimethylsiloxane) (PDMS), viscosity 100 cSt (25 °C); Dimethylsilcone fluid, viscosity 100 cSt (25 °C). CAS No. 63148-62-9. Pack Sizes: 25 mL; 50 mL. Product ID: HY-104035E. | |
| Dimethyl succinate | Dimethyl succinate is an orally active cell permeable succinate analogue. Dimethyl succinate can disrupt the TCA cycle by elevating intracellular succinate levels, leading to reduced protein synthesis and impairs myogenic differentiation. Dimethyl succinate can induce apoptosis. Dimethyl succinate can decrease maximal cellular respiration and reserve capacity. Dimethyl succinate can rescue synapse loss in AD. Dimethyl succinate can be used for the researches of metabolic and neurological disease[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 106-65-0. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-Y0808. | |
| Dimethyl sulfone | Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 67-71-0. Pack Sizes: 10 mM * 1 mL in Water; 5 g; 10 g; 50 g; 100 g; 500 g; 1 k g. Product ID: HY-Y1314. | |
| Dimethyl sulfoxide | Dimethyl sulfoxide (DMSO) is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity[1]. Low endotoxin, can be used in various biochemical experiments such as drug dissolution. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DMSO. CAS No. 67-68-5. Pack Sizes: 100 mL; 200 mL; 500 mL. Product ID: HY-Y0320C. | |
| Dimethyl sulfoxide, cryoprotectant vitrification agent | Dimethyl sulfoxide, cryoprotectant vitrification agent (DMSO, cryoprotectant vitrification agent) is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1]. This product has been sterilized and has no endotoxin. It can be used for long-term cell cryopreservation and will not affect the normal growth of cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DMSO, cryoprotectant vitrification agent; Dimethyl sulfoxide vitrification agent. CAS No. 67-68-5. Pack Sizes: 5 mL; 10 mL; 50 mL; 100 mL. Product ID: HY-Y0320D. | |
| Dimethyl sulfoxide (GMP Like) | Dimethyl sulfoxide (DMSO) (GMP Like) is the GMP Like class Dimethyl sulfoxide (HY-Y0320C). Dimethyl sulfoxide is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DMSO (GMP Like). CAS No. 67-68-5. Pack Sizes: 10 mL; 50 mL; 100 mL. Product ID: HY-Y0320GL. | |
| Dimethyl sulfoxide, meets analytical specification of Ch.P. | Dimethyl sulfoxide (DMSO), meets analytical specification of Ch.P. is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties[1][2][3].MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition). Amicrobic, low endotoxin, can be used in various biochemical experiments such as drug dissolution. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DMSO, meets analytical specification of Ch.P. CAS No. 67-68-5. Pack Sizes: 10 mL; 100 mL; 200 mL; 500 mL. Product ID: HY-Y0320. | |
| Dimethyl sulfoxide (Standard) | Dimethyl sulfoxide (Standard) is the analytical standard of Dimethyl sulfoxide. This product is intended for research and analytical applications. Dimethyl sulfoxide (DMSO) is an aprotic solvent that dissolves both polar and nonpolar compounds. Dimethyl sulfoxide has anti-freezing and bacteriostatic properties[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DMSO, meets analytical specification of Ch.P. (Standard). CAS No. 67-68-5. Pack Sizes: 1 mL; 5 mL; 10 mL. Product ID: HY-Y0320R. | |
| Diminazene aceturate | Diminazene aceturate (Diminazene diaceturate) is an anti-trypanosome agent for livestock. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Diminazene diaceturate. CAS No. 908-54-3. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg. Product ID: HY-12404. | |
| DiMNF | DiMNF (3',4'-Dimethoxy-αNF) is a selective aryl hydrocarbon receptor (AHR) modulator. DiMNF is a competitive AHR ligand (IC50 = 21 nM) with apparent antagonistic activity. DiMNF can be used as an anti-inflammatory agent[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3',4'-Dimethoxy-αNF. CAS No. 14756-24-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103222. | |
| Dinaciclib | Dinaciclib (SCH 727965) is a potent inhibitor of CDK, with IC50s of 1 nM, 1 nM, 3 nM, and 4 nM for CDK2, CDK5, CDK1, and CDK9, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SCH 727965. CAS No. 779353-01-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10492. | |
| Dinoprost | Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Prostaglandin F2α; PGF2α. CAS No. 551-11-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12956. | |
| Dinotefuran | Dinotefuran is an orally active and competitive inhibitor and insecticide targeting insect nicotinic acetylcholine receptors (nAChRs). Dinotefuran blocks neural signaling and induces neural dysfunction in insects. Dinotefuran binds to [3H]epibatidine in the neural cord membrane of American cockroach with an IC50 of 890 nM and to [3H]α-bungarotoxin with an IC50 of 36.1 μM. Dinotefuran exhibits knockdown activity (KD50=0.351 nmol/g) and lethal activity (LD50=0.173 nmol/g) against German cockroach. Dinotefuran is mainly used for agricultural pest control, such as field control of piercing-sucking and chewing insects (e.g., aphids, planthoppers), while its environmental toxicological effects (e.g., oxidative stress and reproductive neurotoxicity on earthworms) are also a research focus to assess ecological risks[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MTI-446. CAS No. 165252-70-0. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 1 g. Product ID: HY-B0827. | |
| Di(N-succinimidyl)adipate | Di(N-succinimidyl)adipate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 59156-70-6. Pack Sizes: 250 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-141099. | |
| Dinutuximab | Dinutuximab (APN-311) is a chimeric human-mouse anti-GD2 monoclonal antibody. Dinutuximab can bind to GD2 on the cell surface, triggering antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity, and promoting tumor regression. Dinutuximab can inhibit the growth, invasion, and migration and induce apoptosis of tumor cells. Dinutuximab can be used in the research of tumors such as neuroblastoma and breast cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: APN-311; Ch14.18; MAb-14.18. CAS No. 1363687-32-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9933. | |
| DiO | DiO is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DiOC18(3); 3,3'-Dioctadecyloxacarbocyanine perchlorate. CAS No. 34215-57-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0969. | |
| Dioscin | Dioscin (CCRIS 4123; Collettiside III) is a natural plant-derived steroidal saponin that has good anti-cancer activity against a variety of cancer cells. Dioscin causes DNA damage and induces apoptosis in HeLa and SiHa cells. Dioscin regulates ROS-mediated DNA damage and mitochondrial signaling pathways, exerting anticancer activity[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Collettiside III; CCRIS 4123. CAS No. 19057-60-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0124. | |
| Dioscin (Standard) | Dioscin (Standard) is the analytical standard of Dioscin. This product is intended for research and analytical applications. Dioscin (CCRIS 4123; Collettiside III) is a natural plant-derived steroidal saponin that has good anti-cancer activity against a variety of cancer cells. Dioscin causes DNA damage and induces apoptosis in HeLa and SiHa cells. Dioscin regulates ROS-mediated DNA damage and mitochondrial signaling pathways, exerting anticancer activity[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Collettiside III (Standard); CCRIS 4123 (Standard). CAS No. 19057-60-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0124R. | |
| Diosgenin | Diosgenin, a steroidal saponin, can inhibit STAT3 signaling pathway[1]. Diosgenin is an exogenous activator of Pdia3/ERp57[2]. Diosgenin inhibits aortic atherosclerosis progression by suppressing macrophage miR-19b expression[5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 512-04-9. Pack Sizes: 100 mg; 500 mg. Product ID: HY-N0177. | |
| Diosmetin | Diosmetin is a natural flavonoid which inhibits human CYP1A enzyme activity with an IC50 of 40 μM in HepG2 cell. Uses: Scientific research. Category: Signaling pathways. CAS No. 520-34-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg. Product ID: HY-N0125. | |
| Diosmetin-7-O-β-D-glucopyranoside | Diosmetin-7-O-β-D-glucopyranoside is a natural product that can be isolated from the flowers of Chrysanthemum morifolium. Diosmetin-7-O-β-D-glucopyranoside has potent antiviral and anti-inflammatory activities against SARS-CoV-2 both in vitro (IC50 = 0.74 μM) and in vivo. Diosmetin-7-O-β-D-glucopyranoside has significant anti-thrombotic activity when combined with Pae and 5-HMF at a ratio of 3:4:3 in a zebrafish model[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 20126-59-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N0713. | |
| DiosMetin 7-O-β-D-Glucuronide | DiosMetin 7-O-β-D-Glucuronide is an antioxidant constituent in the fruits of Luffa cylindrical[1]. Uses: Scientific research. Category: Natural products. CAS No. 35110-20-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N6879. | |
| Diosmin | Diosmin is a flavonoid found in a variety of citrus fruits and also an agonist of the aryl hydrocarbon receptor (AhR). Uses: Scientific research. Category: Signaling pathways. CAS No. 520-27-4. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-N0178. | |
| Dipeptide 2 | Dipeptide 2 (N-Valyltryptophan) is an orally active, competitive angiotensin-converting enzyme (ACE) inhibitory peptide with an IC50 of 10.50 μM. Dipeptide 2 reduces intracellular Calcium ions. Dipeptide 2 significantly increases the content of NO, inhibits the production of ET-1, and induces the phosphorylation of eNOS. Dipeptide 2 decreases the systolic and diastolic blood pressure of spontaneously hypertensive rats[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Valyltryptophan; Val-Trp. CAS No. 24587-37-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 25 g. Product ID: HY-118060. | |
| Dipeptide diaminobutyroyl benzylamide diacetate | Dipeptide diaminobutyroyl benzylamide diacetate, a Wagerlin-1-mimicking peptide, is a nAChR antagonist. Dipeptide diaminobutyroyl benzylamide diacetate mimics Waglerin-1 to block neuromuscular junction nicotinic acetylcholine receptors, partially inhibits neuronal signal transduction, and relaxes muscles. Dipeptide diaminobutyroyl benzylamide diacetate reduces appearance of facial wrinkles linked to repeated muscle movement.Dipeptide diaminobutyroyl benzylamide diacetate can be used for the research of mild-to-moderate fine and coarse periocular and perioral wrinkles and periorbital ageing[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 823202-99-9. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-P0102. | |
| Diphenhydramine | Diphenhydramine is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) [1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 58-73-1. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg. Product ID: HY-B0303. | |
| Diphenhydramine hydrochloride | Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 147-24-0. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 500 mg; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-B0303A. | |
| Diphenyl-1-pyrenylphosphine | Diphenyl-1-pyrenylphosphine (DPPP) is a functional organic molecule with both fluorescent properties and metal coordination ability, which is commonly used in materials and coordination chemistry research. Upon exposure to ultraviolet light, Diphenyl-1-pyrenylphosphine undergoes photoinduced phosphorus atom oxidation to form O-DPPP, triggering a transition from aggregation-induced emission (AIE) to aggregation-caused quenching (ACQ). Diphenyl-1-pyrenylphosphine reacts stoichiometrically with lipid hydroperoxides to produce fluorescent diphenyl-1-pyrenylphosphine oxide. Diphenyl-1-pyrenylphosphine can insert into cell membranes to monitor lipid peroxidation processes in living cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DPPP. CAS No. 110231-30-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-118159. | |
| Diphenylcyclopropenone | Diphenylcyclopropenone (Diphencyprone) is a potent hapten acting as a topical immunomodulatory agent, which induces an allergic contact dermatitis. Diphenylcyclopropenone induces an increase of cell-surface thiols in cells of a human monocytic cell line, THP-1. Diphenylcyclopropenone acts on the autoreactive T-lymphocytes within the follicular milieu to induce Apoptosis. Diphenylcyclopropenone can be used for alopecia areata research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Diphencyprone. CAS No. 886-38-4. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-W014605. | |
| Diphenyleneiodonium chloride | Diphenyleneiodonium chloride is a NADPH oxidase (NOX) inhibitor and also functions as a TRPA1 activator with an EC50 of 1 to 3 μM. Diphenyleneiodonium chloride selectively inhibits intracellular reactive oxygen species. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DPI. CAS No. 4673-26-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-100965. | |
| Diphenylterazine | Diphenylterazine (DTZ) is a bioluminescence agent. Diphenylterazine alone yielded very little background, leading to excellent signal-to-background ratios[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DTZ. CAS No. 344940-63-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-111382. | |
| Diphyllin | Diphyllin is an orally active V-ATPase inhibitor (IC50=17 nM) and HIV-1 inhibitor (IC50=0.38 μM). Diphyllin blocks the acidification of osteoclast lysosomes and bone resorption lacunas (IC50=0.6 nM for acid influx inhibition), thereby inhibiting bone resorption. Diphyllin can effectively inhibit osteoclast-mediated bone resorption and has no effect on osteoblastic bone formation. Diphyllin can be used in the research of bone metabolism-related diseases and has the potential to inhibit diseases related to excessive bone resorption[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 22055-22-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2532. | |
| Dipotassium glycyrrhizinate | Dipotassium glycyrrhizinate is a HMGB1 inhibitor, inhibits atopic dermatitis-related gene expression with anti-anti-inflammatory activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glycyrrhizic acid dipotassium; Dipotassium glycyrrhizate. CAS No. 68797-35-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg. Product ID: HY-N0184A. | |
| Dipotassium glycyrrhizinate (Standard) | Dipotassium glycyrrhizinate (Standard) is the analytical standard of Dipotassium glycyrrhizinate. This product is intended for research and analytical applications. Dipotassium glycyrrhizinate is a HMGB1 inhibitor, inhibits atopic dermatitis-related gene expression with anti-anti-inflammatory activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glycyrrhizic acid dipotassium (Standard); Dipotassium glycyrrhizate (Standard). CAS No. 68797-35-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0184AR. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.