MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Dipotassium hydrogen phosphate | Dipotassium hydrogen phosphate is a salt. Dipotassium hydrogen phosphate can enhance the lipase production of Rhizopous oligosporous in neutral pH phosphate buffer. Dipotassium hydrogen phosphate can be used as a pharmaceutical excipient, such as a pH adjuster, a buffer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 7758-11-4. Pack Sizes: 10 mM * 1 mL in Water; 50 g; 100 g; 250 g; 500 g. Product ID: HY-W019883. |  |
| Dipotassium tetrachloroplatinate | Dipotassium tetrachloroplatinate (Potassium tetrachloroplatinate (?)) is an important reagent for the preparation of other platinum coordination complexes. Dipotassium tetrachloroplatinate acts as a radiosensitizer to enhance the killing effect of hyperthermia. Dipotassium tetrachloroplatinate serves as a catalyst. Dipotassium tetrachloroplatinate exhibits antitumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Potassium tetrachloroplatinate(?). CAS No. 10025-99-7. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-112030. | |
| Dipropetryn | Dipropetryn (GS 16068) is a compound that inhibits algal photosynthesis and toxin production. It can reduce the photosynthetic activity and pigment content of Karenia, reduce the levels of unsaturated fatty acids, reactive oxygen and hemolytic toxins, and regulate the expression of related proteins. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS 16068; Sancap; Cotofor. CAS No. 4147-51-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-B1977. | |
| Diprotin A | Diprotin A (Ile-Pro-Ile) is an inhibitor of dipeptidyl peptidase IV (DPP-IV)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ile-Pro-Ile. CAS No. 90614-48-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-111174. | |
| Diprovocim | Diprovocim is a potent TLR1/TLR2 agonist. Diprovocim elicits full agonist activity in human THP-1 cells (EC50=110 pM). Diprovocim stimulates the release of TNF-α from mouse macrophages (EC50=1.3 nM). Diprovocim activates downstream MAPK and NF-κB signaling pathway. Diprovocim displays strong adjuvant activity in mice, particularly abetting cellular immune responses[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2170867-89-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123942. | |
| Dipsacoside B | Dipsacoside B is a major bioactive saponin, which can be used as a marker. Uses: Scientific research. Category: Natural products. CAS No. 33289-85-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0266. | |
| Dipyridamole | Dipyridamole is an orally active phosphodiesterase (PDE) inhibitor. Dipyridamole also is an antiplatelet agent used in secondary prophylaxis against stroke. Dipyridamole can induce cancer cell-specific apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 58-32-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B0312. | |
| Diquafosol tetrasodium | Diquafosol tetrasodium is a P2Y2 receptor agonist that stimulates fluid and mucin secretion on the ocular surface, as a topical treatment of dry eye disease. Uses: Scientific research. Category: Signaling pathways. Alternative Names: INS365. CAS No. 211427-08-6. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0606. | |
| DiR | DiR is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cy7 DiC18. CAS No. 100068-60-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1048. | |
| Diranersen | Diranersen (IONIS-MAPTRx) is an antisense oligonucleotide that targets the human MAPT gene to inhibit the production of tau protein. Diranersen can be used in research related to Alzheimer's disease and tauopathies[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IONIS-MAPTRx; BIIB080; ISIS 814907. CAS No. 2304711-06-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132582. | |
| Direct Blue 1 | Direct Blue 1 (Chicago Sky Blue 6B) is a complex dye for background autofluorescence in immunofluorescence histochemistry. Direct Blue 1 is a potent and competitive VGLUT inhibitor. Direct Blue 1 can inhibit the Aβ-binding small molecule PrP ligand. Direct Blue 1 has anti-inflammatory activity[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Chicago Sky Blue 6B. CAS No. 2610-5-1. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg. Product ID: HY-D0939. | |
| Direct Red 80 | Direct Red 80 (Sirius Red) is a polyazo dye used principally in staining methods for collagen and amyloid. Direct Red 80 does not release benzidine upon degradation and is safer than many traditional direct dyes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sirius Red. CAS No. 2610-10-8. Pack Sizes: 1 g. Product ID: HY-D0333. | |
| Diridavumab | Diridavumab is a monoclonal anti-HA stalk antibody. Diridavumab stabilizes the prefusion HA structure and prevents pH-dependent fusion of cellular and viral membranes in endosomes. Diridavumab can be used in research of H2 influenza virus[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CR6261. CAS No. 1393659-46-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99853. | |
| Diroximel fumarate | Diroximel fumarate (ALKS 8700) is an orally-active and well-tolerated monomethyl fumarate (MMF) proagent in a controlled-release formulation. Diroximel fumarate is considered as active equivalent to its active metabolite dimethyl fumarate (DMF). Diroximel fumarate has a favorable safety and efficacy profile, has the potential for the study of multiple sclerosis (MS). Diroximel fumarate is a Nrf2 activator that alleviate MGO-induced pain hypersensitivity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALKS 8700; BIIB098. CAS No. 1577222-14-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100375. | |
| DiSC3(5) | DiSC3(5) is a fluorescent probe commonly used as a tracer dye to evaluate mitochondrial membrane potential. The excitation/emission wavelength of DiSC3(5) is up to 622/670 nm. DiSC3(5) can inhibit the respiratory system associated with mitochondrial NAD, and the IC50 value is 8 μM. DiSC3(5) in the presence of Na+/K+-ATPase inhibitor ouabain 2 can induce membrane hyperpolarization of Ehrlich ascites tumor cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 53213-94-8. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-D0085. | |
| Disitamab | Disitamab (RC48-0) is a humanized monoclonal antibody targeting HER2. Disitamab can be used in the synthesis of antibody-drug conjugates (ADCs), Disitamab vedotin (HY-P9985)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RC48-0. CAS No. 2185868-98-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99854. | |
| Disitamab vedotin | Disitamab vedotin (RC48) is an antibody-drug conjugate (ADC) comprising a monoclonal antibody against human epidermal growth factor receptor 2 (HER2) conjugated via a cleavable linker to the cytotoxic agent Monomethyl auristatin E (MMAE) (HY-15162), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E). Disitamab vedotin enhances antitumor immunity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RC48. CAS No. 2136633-23-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9985. | |
| Disodium carbamyl phosphate | Disodium carbamyl phosphate is an antisickling agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 72461-86-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-160120. | |
| Disodium phosphate | Disodium phosphate is commonly used as a food additive, buffer and laboratory reagent. Disodium phosphate has unique chemical properties that make it an important ingredient in the manufacture of fertilizers, detergents and water treatment products. Additionally, it is used in various medical applications such as osmotic laxatives and electrolyte replacement solutions. Uses: Scientific research. Category: Signaling pathways. CAS No. 7558-79-4. Pack Sizes: 10 mM * 1 mL in Water; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-Y0308. | |
| Disodium succinate | Disodium succinate is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Disodium succinate is an intermediate product of the tricarboxylic acid cycle. Disodium succinate is an important platform chemical. Disodium succinate can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 150-90-3. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W015410. | |
| D-Isoleucine | D-Isoleucine is a selective competitive activator of the Asc-1 antiporter (Ki=0.98 mM). D-Isoleucine promotes the release of D-serine and glycine by binding to the Asc-1 protein on the neuronal cell membrane, and enhances NMDA receptor-dependent synaptic plasticity. D-Isoleucine can be used in the study of neurodegenerative diseases (such as Alzheimer's disease and schizophrenia). D-Isoleucine also acts as a non-classical D-amino acid, interferes with bacterial peptidoglycan synthesis, and inhibits the formation of Staphylococcus aureus biofilm, and has potential antibacterial application value[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-Isoleucine. CAS No. 319-78-8. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-I1070. | |
| Disopyramide | Disopyramide (Dicorantil) is a class IA antiarrhythmic agent with efficacy in ventricular and atrial arrhythmias. Disopyramide blocks the fast inward sodium current of cardiac muscle and prolongs the duration of cardiac action potentials. Disopyramide inhibits HERG encoded potassium channels. Disopyramide also exhibits complex protein binding, and has a potent negative inotropic action[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dicorantil; SC-7031. CAS No. 3737-9-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12533. | |
| Disoxaril | Disoxaril (WIN-51711) is an antivirus agent with activity against poliovirus types 1 and 2. Disoxaril inserts into the hydrophobic interior of virus capsid protein VP1 to stabilize virion conformation, inhibits poliovirus uncoating, and prevents viral RNA release and synthesis. Disoxaril can be used for the research of poliovirus infection[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: WIN-51711. CAS No. 87495-31-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111233. | |
| Displurigen | Displurigen (NSC375009) disrupts human embryonic stem cell pluripotency by targeting HSPA8. Displurigen inhibits ATPase activity of HSP70 (IC50 = 225 μM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC375009. CAS No. 96156-26-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111002. | |
| Distearoylphosphatidylserine sodium | Distearoylphosphatidylserine sodium is an anionic phospholipid with stearic acid tails (18:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DSPS sodium. CAS No. 321595-13-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W440986. | |
| Disuccinimidyl suberate Crosslinker | Disuccinimidyl suberate Crosslinker is an amine-reactive bifunctional protein crosslinker. Disuccinimidyl suberate Crosslinker enables stable protein-protein, peptide, and biomolecule conjugation. Uses: Scientific research. Category: Signaling pathways. CAS No. 68528-80-3. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-W019543. | |
| Disuccinimidyl sulfoxide | Disuccinimidyl sulfoxide (DSSO) is a sulfoxide-containing crosslinker targeting amino groups that can be cleaved by MS, and it is suitable for model peptides, proteins, and multisubunit protein complexes. Disuccinimidyl sulfoxide contains two symmetric collision-induced dissociation (CID)-cleavable sites, enabling the identification of DSSO-crosslinked peptides based on different fragmentation patterns[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DSSO. CAS No. 1351828-03-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-123740. | |
| Disufenton sodium | Disufenton sodium (NXY-059) scavenges free radicals, reduces ischemic damage and exhibits neuroprotective effects[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NXY-059. CAS No. 168021-79-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13244. | |
| Disulfiram | Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells. Disulfiram, a copper ion carrier,?with?Cu2+ increases intracellular ROS levels and induces cuproptosis[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tetraethylthiuram disulfide; TETD. CAS No. 97-77-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0240. | |
| Disulfiram (Standard) | Disulfiram (Standard) is the analytical standard of Disulfiram. This product is intended for research and analytical applications. Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells. Disulfiram?+?Cu2+ increases intracellular ROS levels triggering apoptosis of ovarian cancer stem cells[1-6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tetraethylthiuram disulfide (Standard); TETD (Standard). CAS No. 97-77-8. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0240R. | |
| Ditercalinium chloride | Ditercalinium chloride is an anticancer agent. Ditercalinium chloride inhibits human DNA polymerase gamma activity. Ditercalinium chloride can deplete mitochondrial DNA in both mouse and human cells. Ditercalinium chloride is a potential ligand against the COMMD10-AP3S1 fusion protein[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC335153. CAS No. 74517-42-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-19587. | |
| Di-tert-butyl dicarbonate | Di-tert-butyl dicarbonate (tBOC) is a covalent modification agent for hydroxyl groups (-OH) on the chitosan molecular chain. Di-tert-butyl dicarbonate selectively modifies chitosan and stabilizes the material structure through hydrophobic encapsulation. Di-tert-butyl dicarbonate reacts with the -OH groups of chitosan to form a hydrophobic layer, and in conjunction with triethylamine (TEA), removes trifluoroacetic acid (TFA) salts produced during the electrospinning process, preserving the nanofiber structure and high porosity of the membrane, and improving the material's cytocompatibility and mineralization-promoting ability. Di-tert-butyl dicarbonate can be used in research in the field of guided bone regeneration (GBR)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 24424-99-5. Pack Sizes: 100 g; 500 g. Product ID: HY-Y1353. | |
| Dithranol | Dithranol (Anthralin) is an anthraquinone derivative, with potent anti-psoriatic effects. Dithranol can inhibit DNA replication and repair[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anthralin. CAS No. 1143-38-0. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-B0738. | |
| Diuron | Diuron is an orally active phenylurea herbicide. Diuron inhibits photosynthesis in plants by blocking the formation of ATP and NADH. Diuron increases the production of ROS. Diuron increases expression of p53 in certain cell lines. Diuron has herbicidal activity against annual and perennial broadleaf weeds and grass weeds. Diuron promotes DMBA/BBN-induced bladder cancer. Diuron can be used in breast cancer research[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 330-54-1. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0860. | |
| Divarasib | Divarasib (GDC-6036) is an orally active, selective KRASG12C inhibitor with an IC50 of <0.01 μM. Divarasib covalently binds Cys12 in GDP-bound KRASG12C, occupies the switch II pocket, blocks GTP binding and SOS-mediated reactivation, and inhibits oncogenic KRAS signaling. Divarasib induces tumor shrinkage and robust tumor growth inhibition in KRASG12C-positive models and cancer cells. Divarasib can be used for the research of non-small cell lung cancer, colorectal adenocarcinoma, pancreatic ductal adenocarcinoma, and other KRASG12C-mutated solid tumors[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GDC-6036. CAS No. 2417987-45-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145928. | |
| Divarasib adipate | Divarasib (GDC-6036) adipate is an orally active, selective KRASG12C inhibitor with an IC50 of <0.01 μM. Divarasib adipate covalently binds Cys12 in GDP-bound KRASG12C, occupies the switch II pocket, blocks GTP binding and SOS-mediated reactivation, and inhibits oncogenic KRAS signaling. Divarasib adipate induces tumor shrinkage and robust tumor growth inhibition in KRASG12C-positive models and cancer cells. Divarasib adipate can be used for the research of non-small cell lung cancer, colorectal adenocarcinoma, pancreatic ductal adenocarcinoma, and other KRASG12C-mutated solid tumors[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GDC-6036 adipate. CAS No. 2762240-36-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145928B. | |
| DiZHSeC | DiZHSeC is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 2230724-46-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D1032. | |
| Dizocilpine | Dizocilpine (MK-801), a potent anticonvulsant, is a selective and non-competitive NMDA receptor antagonist, with a Kd of 37.2 nM in rat brain membranes. Dizocilpine acts by binding to a site located within the NMDA associated ion channel and thus prevents Ca2+ flux[1][2]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: MK-801. CAS No. 77086-21-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15084B. | |
| (-)-Dizocilpine maleate | (-)-Dizocilpine maleate ((-)-MK-801 maleate) is a less active (-)-enantiomer of Dizocilpine. (-)-Dizocilpine maleate is a selective and non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist with a Ki of 211.7 nM. (-)-Dizocilpine maleate has antidepressant effects[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-MK-801 maleate. CAS No. 121917-57-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15084A. | |
| Dizocilpine maleate | Dizocilpine maleate (MK-801 maleate) is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes. Uses: Scientific research. Category: Induced disease models products. Alternative Names: (+)-MK 801 Maleate. CAS No. 77086-22-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15084. | |
| DJ001 | DJ001 is a highly specific, selective and non-competitive protein tyrosine phosphatase-σ (PTPσ) inhibitor with an IC50 of 1.43 μM. DJ001 displays no inhibitory activity against other phosphatases, with only modest inhibitory activity against Protein Phosphatase 5. DJ001 promotes promote hematopoietic stem cell regeneration[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2161305-12-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133146. | |
| D-JNKI-1 | D-JNKI-1 (AM-111) is a highly potent and cell-permeable peptide inhibitor of JNK. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AM-111; XG-102. CAS No. 1445179-97-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0069. | |
| DK2403 | DK2403 (compound 25) is a MAP2K7 inhibitor (IC50= 0.01 μM). DK2403 can effectively inhibit MAP2K7 without significantly disrupting the larger kinase group and can be used to study childhood T-cell acute lymphoblastic leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2902651-64-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-171178. | |
| DK3 | DK3 is a potent and selective estrogen-related receptor alpha (ERRα) agonist[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1187568-16-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143227. | |
| DKFZ-748 | DKFZ-748 is a selective HDAC10 inhibitor (pIC50=7.66), and shows anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2490709-68-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151590. | |
| D-Kynurenine | D-kynurenine, a metabolite of D-tryptophan, can serve as the bioprecursor of kynurenic acid (KYNA) and 3-hydroxykynurenine. D-Kynurenine is an agonist for G protein-coupled receptor, GPR109B. D-Kynurenine is a substrate in a fluorometric assay of D-amino acid oxidase. D-kynurenine promotes epithelial-to-mesenchymal transition via activating aryl hydrocarbon receptor (AHR)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 13441-51-5. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg. Product ID: HY-W014502. | |
| DL-01 formic | DL-01 formic is a drug-linker conjugates for ADC that can be used for the synthesis of ADCs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2964513-44-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-155870A. | |
| DL-3-Phenyllactic acid-d3 | DL-3-Phenyllactic acid-d3 is a deuterated labeled DL-3-Phenyllactic acid[1]. DL-3-Phenyllactic acid is a broad-spectrum antimicrobial compound. Uses: Scientific research. Category: Signaling pathways. CAS No. 490034-49-6. Pack Sizes: 500 μg; 1 mg. Product ID: HY-W017162S. | |
| DL-Allylglycine | DL-Allylglycine (2-Aminopent-4-enoic acid) is a glutamate decarboxylase (GAD) inhibitor. DL-Allylglycine significantly increases mouse brain ornithine decarboxylase (ODC) activity and decreases S-adenosyl-L-methionine decarboxylase (SAM-DC) activity. DL-Allylglycine causes a marked decrease in brain GABA concentration. DL-Allylglycine has convulsant activity that can be used in studies to induce epileptic seizures[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Aminopent-4-enoic acid. CAS No. 7685-44-1. Pack Sizes: 10 mM * 1 mL in Water; 5 g; 10 g; 25 g; 100 g. Product ID: HY-W023493. | |
| DL-α-(Difluoromethyl)arginine | DL-α-(Difluoromethyl)arginine is an potent, enzyme-activated and irreversible arginine decarboxylases inhibitor. DL-α-(Difluoromethyl)arginine blocks the arginine decarboxylase activity of E.coli and Pseudomonas aeruginosa in vivo[1]. Uses: Scientific research. Category: Peptides. CAS No. 69955-43-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-134161. | |
| DL-alpha-Tocopherol | DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DL-α-Tocopherol. CAS No. 10191-41-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-W020044. | |
| DL-α-Tocopherol acetate | DL-α-Tocopherol acetate is a vitamin E derivative which is often included in the formulations of enteral nutrition. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vitamin E acetate. CAS No. 52225-20-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-B1278A. | |
| DL-alpha-Tocopherol (Standard) | DL-alpha-Tocopherol (Standard) is the analytical standard of DL-alpha-Tocopherol. This product is intended for research and analytical applications. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DL-α-Tocopherol (Standard). CAS No. 10191-41-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W020044R. | |
| DL-AP4 | DL-AP4 (2-Amino-4-phosphonobutyric acid) is a glutamate antagonist. DL-AP4 behaves as a competitive inhibitor of glutamate binding with an apparent Kd of 66 μM. DL-AP4 can be used for the research of central nervous system and visual system[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Amino-4-phosphonobutyric acid. CAS No. 6323-99-5. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg. Product ID: HY-100743. | |
| DL-AP5 | DL-AP5 (2-APV) is a competitive NMDA (N-methyl-D-aspartate) receptor antagonist. DL-AP5 shows significantly antinociceptive activity. DL-AP5 specifically blocks on channels in the rabbit retina[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-APV; DL-2-Amino-5-phosphonovaleric acid. CAS No. 76326-31-3. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100714. | |
| DL-AP5 sodium | DL-AP5 (2-APV) sodium is a competitive NMDA (N-methyl-D-aspartate) receptor antagonist. DL-AP5 sodium shows significantly antinociceptive activity. DL-AP5 sodium specifically blocks on channels in the rabbit retina[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-APV sodium; DL-2-Amino-5-phosphonovaleric acid sodium. CAS No. 1303993-72-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-100714C. | |
| DL-β-Hydroxybutyryl coenzyme A lithium | DL-β-Hydroxybutyryl coenzyme A lithium is an intermediate in the fermentation of butyric acid and the metabolism of lysine and tryptophan, and is produced from β-hydroxybutyric acid by short-chain-CoA synthase[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 103404-51-9. Pack Sizes: 1 mg. Product ID: HY-134426. | |
| DL-Buthionine-(S,R)-sulfoximine | DL-Buthionine-(S,R)-sulfoximine is a potent inhibitor of glutamylcysteine synthetase biosynthesis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Buthionine sulfoximine; BSO. CAS No. 5072-26-4. Pack Sizes: 10 mM * 1 mL in Water; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-106376. | |
| DL-Cystine-d6 | DL-Cystine-d6 is the deuterium labeled DL-Cystine (HY-W013940). DL-Cystine is a cysteine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 352431-53-9. Pack Sizes: 1 mg; 10 mg. Product ID: HY-W013940S1. | |
| DL-Dipalmitoylphosphatidylcholine | DL-Dipalmitoylphosphatidylcholine (DL-DPPC) is a biochemical reagent. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DL-DPPC. CAS No. 2644-64-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W718223. | |
| DL-Dithiothreitol | DL-Dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. When DL-Dithiothreitol is oxidized, it forms a stable six-membered ring with an internal disulfide bond[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DTT; rel-(2R,3R)-1,4-Dimercapto-2,3-butanediol. CAS No. 3483-12-3. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-15917. | |
| DL-Dithiothreitol-d6 | DL-Dithiothreitol-d6 is the deuterated form of DL-Dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. DL-dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DTT-d6. CAS No. 850153-85-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-15917S2. | |
| D-Leucine-d10 | D-Leucine-d10 is the deuterium labeled D-Leucine. D-Leucine is a more potent anti-seizure agent than L-leucine. D-leucine potently terminates seizures even after the onset of seizure activity. D-leucine, but not L-leucine, reduces long-term potentiation but had no effect on basal synaptic transmission in vitro[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-Leucine-d10. CAS No. 271247-12-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-Y0378S. | |
| DL-Gabaculine hydrochloride | DL-Gabaculine hydrochloride is a neurotoxin that irreversibly inhibits bacterial pyridoxal phosphate linked γ-aminobutyric acid-α-ketoglutaric acid transaminase with a Ki of 2.86 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 59556-17-1. Pack Sizes: 1 mg. Product ID: HY-15377. | |
| DL-Glyceraldehyde 3-phosphate | DL-Glyceraldehyde 3-phosphate is an intermediate in several metabolic pathways, including glycolysis and gluconeogenesis. DL-Glyceraldehyde 3-phosphate is a potent inhibitor of the growth of E. coli. DL-Glyceraldehyde 3-phosphate is a competitive inhibitor of the acyltransferase[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 591-59-3. Pack Sizes: 5 mg (294 mM * 100 μL in Water); 10 mg (294 mM * 200 μL in Water). Product ID: HY-113054. | |
| DL-Histidine-d3 | DL-Histidine-d3 is the deuterium labeled DL-Histidine. Uses: Scientific research. Category: Signaling pathways. CAS No. 344299-50-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W010209S2. | |
| DL-Homocysteine | DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain. DL-Homocysteine is correlated with Vitamin B12, renal functions and folate levels, affects the cross-sectional cognition indirectly through white matter microstructural integrity[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 454-29-5. Pack Sizes: 10 mM * 1 mL in Water; 100 mg. Product ID: HY-W040821. | |
| DL-Homocysteine-d4 | DL-Homocysteine-d4 is the deuterium labeled DL-Homocysteine. DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 416845-90-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W010347S. | |
| DLinDMA | DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 871258-12-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-112757. | |
| DLin-KC2-DMA | DLin-KC2-DMA is an ionisable cationic lipid (pKa?6) that is virtually non-toxic to antigen presenting cells (APCs). DLin-KC2-DMA produces significant siRNA-mediated gene silencing of GAPDH, when binds to lipid nanoparticles (LNP). DLin-KC2-DMA can be used in siRNA delivery studies[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1190197-97-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112758. | |
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