MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| D-Galactose | D-Galactose is a natural aldohexose and C-4 epimer of glucose. Uses: Scientific research. Category: Induced disease models products. Alternative Names: D-(+)-Galactose. CAS No. 59-23-4. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-N0210. |  |
| D-Galactose-13C | D-Galactose-13C is the 13C labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-(+)-Galactose-13C. CAS No. 70849-30-8. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-N0210S. | |
| D-Galactose-13C6 | D-Galactose-13C6 is the C13 labeled D-Galactose (HY-N0210). D-Galactose is a natural aldohexose and C-4 epimer of glucose[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-(+)-Galactose-13C6. CAS No. 74134-89-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0210S16. | |
| D-Galactose-6-O-sulfate sodium salt | D-Galactose-6-O-sulfate sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-Galactose-6-O-sulphate sodium salt. CAS No. 125455-62-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W145673. | |
| D-Galacturonic acid | D-Galacturonic acid (D-galUA), as the main component of pectin, is abundantly present in plants. The carboxyl group of D-Galacturonic acid can bind to metal cations. D-Galacturonic acid plays an important role in the food industry, pharmaceutical field, and heavy metal removal, among other aspects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-galUA. CAS No. 685-73-4. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g. Product ID: HY-B1827A. | |
| DGAT1-IN-1 | DGAT1-IN-1 is a diacylglycerol O-acyltransferase 1 (DGAT1) inhibitor with a human IC50 of <10 nM and a mouse IC50 of <50 nM. DGAT1-IN-1 is applicable to the research of obesity-related diseases, type 2 diabetes and diabetes-related diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1449779-49-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12425. | |
| DGAT1-IN-3 | DGAT1-IN-3 is a potent, selective and orally bioavailable inhibitor of DGAT-1, with IC50s of 38 nM for human DGAT-1 and 120 nM for rat DGAT-1. DGAT1-IN-3 could be used to research of obesity, dyslipidemia, and metabolic syndrome[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 939375-07-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16434. | |
| DGDG | DGDG, a chloroplast lipid, is a bilayer-forming lipid. DGDG is important for photosynthesis, and can be used for drug delivery[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 63142-69-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-143693. | |
| D-Glucamine, 98% | D-Glucamine, 98% (1-Amino-1-deoxy-D-glucitol, 98%) is an amino sugar derivative that serves as an excipient in pharmaceutical formulations. D-Glucamine, 98% also acts as a substrate for studies investigating sugar transporter pathways[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-Amino-1-deoxy-D-glucitol, 98%. CAS No. 488-43-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W016445. | |
| D-Glucosamine 6-phosphate | D-Glucosamine 6-phosphate is an endogenous metabolite that can be synthesized by glutamine fructose-6-phosphate amidotransferase (GFAT). D-Glucosamine 6-phosphate can be used for the research of diabetes mellitus[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glucosamine-6-phosphate; D-GlcN-6-P. CAS No. 3616-42-0. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N11848. | |
| D-Glucose | D-Glucose is the naturally occurring form of glucose and the most abundant monosaccharide. D-Glucose is a critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic or abiotic stress response[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glucose; D-(+)-Glucose; Dextrose. CAS No. 50-99-7. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0389. | |
| D-Glucose-13C | D-Glucose-13C is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glucose-13C; D-(+)-Glucose-13C; Dextrose-13C. CAS No. 101615-88-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-B0389S10. | |
| D-Glucose-13C6 | D-Glucose-13C6 is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose-13C6 can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glucose-13C6; D-(+)-Glucose-13C6; Dextrose-13C6. CAS No. 110187-42-3. Pack Sizes: 10 mM * 1 mL in Water; 50 mg; 100 mg; 250 mg; 1 g; 5 g; 10 g. Product ID: HY-B0389A. | |
| D-Glucose-18O | D-Glucose-18O is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glucose-18O; D-(+)-Glucose-18O; Dextrose-18O. CAS No. 3343-70-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-B0389S29. | |
| D-Glucose 6-phosphate | D-Glucose 6-phosphate is a key central node metabolite in glucose metabolism. It serves as the initiating metabolite for glycolysis and the pentose phosphate pathway, as well as a substrate for glycogen synthesis. D-Glucose 6-phosphate acts as a metabolic stress signal, which activates the mTOR pathway to promote protein synthesis, especially when phosphoglucose isomerase (PGI) is inhibited, thereby participating in cardiac remodeling processes. D-Glucose 6-phosphate can be used in research related to non-insulin-dependent diabetes mellitus and heart failure[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 56-73-5. Pack Sizes: 25 mg (1 M * 96 μL in Water); 50 mg (1 M * 192 μL in Water); 100 mg (1 M * 384 μL in Water). Product ID: HY-112537. | |
| D-Glucose 6-phosphate disodium salt | D-Glucose-6-phosphate disodium salt is a glucose sugar phosphorylated at the hydroxy group on carbon 6[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3671-99-6. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-128374. | |
| D-Glucose-d4 | D-Glucose-d4 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molec. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glucose-d4; D-(+)-Glucose-d4; Dextrose-d4. CAS No. 478529-49-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0389S24. | |
| D-Glucose-d7 | D-Glucose-d77 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glucose-d7; D-(+)-Glucose-d7; Dextrose-d7. CAS No. 66034-51-3. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-B0389S6. | |
| D-Glucose (Standard) | D-Glucose (Standard) is the analytical standard of D-Glucose. This product is intended for research and analytical applications. D-Glucose is the naturally occurring form of glucose and the most abundant monosaccharide. D-Glucose is a critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic or abiotic stress response[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glucose (Standard); D-(+)-Glucose (Standard); Dextrose (Standard). CAS No. 50-99-7. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-B0389R. | |
| D-Glucuronic acid lactone (Standard) | D-Glucuronic acid lactone (Standard) is the analytical standard of D-Glucuronic acid lactone. This product is intended for research and analytical applications. D-Glucuronic acid lactone is an endogenous metabolite. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-Glucurono-6,3-lactone (Standard); D-Glucurono-γ-lactone (Standard); D-Glucuronolactone (Standard); Dicurone (Standard); Glucoxy (Standard); Glucurolactone (Standard); Glucurone (Standard). CAS No. 32449-92-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-41982R. | |
| D-Glucuronic acid (Standard) | D-Glucuronic acid (Standard) is the analytical standard of D-Glucuronic acid. This product is intended for research and analytical applications. D-Glucuronic acid is a major component of many anti-inflammatory proteoglycans, which can promote embryonic development and inhibit cell aggregation. After being metabolized into ethyl glucuronide (HY-113093), D-Glucuronic acid activates Toll-like receptor 4 (TLR4), causing pain. D-Glucuronic acid and its derivative glucurono-lactone can serve as liver detoxifiers for human health prevention, and its derivatives also possess anti-tumor activity[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6556-12-3. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N6612R. | |
| D-Glyceraldehyde 3-phosphate | D-Glyceraldehyde 3-phosphate (Triose phosphate) is a common molecule in living organisms and is an important intermediate in glycolysis and gluconeogenesis, as well as a sugar product of the Calvin cycle. D-Glyceraldehyde 3-phosphate is involved in the biosynthesis of tryptophan and thiamin. D-Glyceraldehyde 3-phosphate is released as aldehyde by aldolase or triose phosphate isomerase. D-Glyceraldehyde 3-phosphate forms adducts with thiols[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Triose phosphate. CAS No. 591-57-1. Pack Sizes: 1 mg (58.80 mM * 100 μL in Water); 5 mg (58.80 mM * 500 μL in Water); 10 mg (58.80 mM * 1 mL in Water). Product ID: HY-151223. | |
| D-Glyceric acid calcium hydrate | D-Glyceric acid calcium hydrate is an endogenous metabolite present in urine that can be used for the research of primary hyperoxaluria type I and glutaric acidemia type 2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6000-41-5. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W584173. | |
| D-Glyceric acid sodium | D-Glyceric acid sodium is the sodium form of D-Glyceric acid (HY-139070A). D-Glyceric acid is an endogenous metabolite present in urine that can be used for the research of primary hyperoxaluria type I and glutaric acidemia type 2[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 109175-64-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-139070A. | |
| DGY-06-116 | DGY-06-116 is an irreversible covalent, selective Src inhibitor with an IC50 of 3nM. DGY-06-116 inhibits FGFR1 with an IC50 of 8340 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2556836-50-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136605. | |
| DGY-09-192 | DGY-09-192 is a PROTAC FGFR1/2 degrader (FGFR1: DC50 = 4.35 nM; FGFR2: DC50 = 70 nM). DGY-09-192 preferentially degrades wild-type FGFR1/2 and multiple FGFR2 fusion proteins (including FGFR2-PHGDH and FGFR2-OPTN). DGY-09-192 suppresses downstream FGFR signaling (reducing phosphorylation of FRS2 Y196 and ERK1/2 T202/Y204) in vitro and vivo. DGY-09-192 can be used for the study of FGFR-driven cancers. (Pink: FGFR1/2 ligand (HY-160013), Blue: VHL Ligand (HY-112078), Black: Linker (HY-W020017))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2504949-52-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-165298. | |
| DHC-156 | DHC-156 is a selective Brachyury small molecule downmodulator. DHC-156 can be used for chordoma research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3115269-32-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157964. | |
| DHEA | DHEA (Prasterone) is one of the most abundant steroid hormones. DHEA (Prasterone) mediates its action via multiple signaling pathways involving specific membrane receptors and via transformation into androgen and estrogen derivatives (e.g., androgens, estrogens, 7α and 7β DHEA, and 7α and 7β epiandrosterone derivatives) acting through their specific receptors. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Prasterone; Dehydroisoandrosterone; Dehydroepiandrosterone. CAS No. 53-43-0. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-14650. | |
| DHEA (Standard) | DHEA (Prasterone) (Standard) is the analytical standard of DHEA. This product is intended for research and analytical applications. DHEA is a steroid hormone[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Prasterone (Standard); Dehydroisoandrosterone (Standard); Dehydroepiandrosterone (Standard). CAS No. 53-43-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14650R. | |
| DHICA | DHICA (5,6-Dihydroxyindole-2-carboxylic acid) is an eumelanin building block, GPR35 agonist and melanin synthesis intermediate. DHICA activates GPR35, triggering dynamic mass redistribution and β-arrestin translocation. DHICA interacts with DNA and interferes with Fpg activity. DHICA promotes the generation of single-strand breaks in plasmid DNA. DHICA increases the activity and expression levels of SOD and Catalase. DHICA is applicable to research related to skin cancer and colon cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5,6-Dihydroxyindole-2-carboxylic acid. CAS No. 4790-8-3. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-W018158. | |
| (D-His2,D-Trp6)-LHRH | (D-His2,D-Trp6)-LHRH ((D-His2)-Triptorelin) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (D-His2)-Triptorelin. CAS No. 321709-34-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P4534. | |
| (-)-DHMEQ | (-)-DHMEQ (Dehydroxymethylepoxyquinomicin) is a potent, selective and irreversible NF-κB inhibitor that covalently binds to a cysteine residue. (-)-DHMEQ inhibits nuclear translocation of NF-κB and shows anti-inflammatory and anticancer activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dehydroxymethylepoxyquinomicin. CAS No. 287194-40-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14645. | |
| DHPG | DHPG is the agonist for mGluR 1/5 (EC50 for mGluR 1 is 60 nM) that activates the phospholipase C (PLC) pathway, and leads ultimately to the activation of protein kinase C (PKC)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (RS)-3,5-DHPG. CAS No. 146255-66-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12598A. | |
| DHQZ 36 | DHQZ 36 is a potent inhibitor of retrograde trafficking. DHQZ 36 inhibits Leishmania amazonensis infection in macrophages with an EC50 of 13.63 μM. DHQZ 36 has potent anti-parasite activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1542098-94-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-123601. | |
| DHTP | DHTP is a kinesin-13 family of microtubule depolymerases selective allosteric inhibitor that inhibits kinesin-13 ATPase activity and microtubule depolymerization activity. DHTP inhibits Kif2a and MCAK with IC50 values of 1.2 μM and 4.6 μM, respectively, and does not inhibit other kinesin families. DHTP modulates microtubule dynamics in cells, leading to less dynamic microtubules. DHTP links kinesin-13 overexpression to cancer and Paclitaxel (HY-B0015) resistance. DHTP can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1620225-37-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-177898. | |
| Dhurrin | Dhurrin is a cyanogenic glucoside isolated from Sorghum[1]. Uses: Scientific research. Category: Natural products. CAS No. 499-20-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N8433. | |
| DHX9-IN-1 | DHX9-IN-1 is an inhibitor of ATP-dependent RNA helicase A (DHX9). Its EC50 value is 1.41 μM. DHX9-IN-1 has anti-tumor activity and can be used in colorectal cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2973747-89-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-156782. | |
| DHX9-IN-3 | DHX9-IN-3 (Compound 621) is an inhibitor of ATP-dependent RNA helicase A (DHX9). DHX9-IN-3 has an IC50 of 8.7 nM for anti-proliferation in LS411N cells. DHX9-IN-3 can be used in the study of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2973401-57-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160007. | |
| DHX9-IN-5 | DHX9-IN-5 (compound 277) is a RNA helicase DHX9 inhibitor with an IC50 of 4.3 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2973398-17-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-160009. | |
| DHX9-IN-9 | DHX9-IN-9 (509) is a RNA helicase DHX9 inhibitor, with an EC50 of 0.0177 μM in DHX9 cellular target engagement. Used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2973400-46-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157604. | |
| D-I03 | D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 μM. D-I03 specifically inhibits RAD52-dependent single-strand annealing (SSA) and D-loop formation with IC50s of 5 μM and 8 μM, respectively. D-I03 suppresses growth of BRCA1- and BRCA2-deficient cells and inhibits formation of damage-induced RAD52 foci, but does not effect on RAD51 foci induced by Cisplatin[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 688342-78-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-124691. | |
| DI-1859 | DI-1859 is a potent, selective and covalent inhibitor of DCN1. DI-1859 inhibits neddylation of cullin 3 in cells at low nanomolar concentrations. DI-1859 induces a robust increase of NRF2 protein, a CRL3 substrate, in mouse liver and effectively protects mice from acetaminophen-induced liver damage[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2247061-09-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145733. | |
| Di(1H-pyrrol-2-yl)methane | Di(1H-pyrrol-2-yl)methane (Dipyrrolylmethane) is a metal-organic framework (MOF). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dipyrrolylmethane. CAS No. 21211-65-4. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W017510. | |
| Di-4-ANEPPDHQ | Di-4-ANEPPDHQ is a polarity-sensitive membrane probe with a doubly positive charge that can be used to visualize membrane microdomains in living Arabidopsis cells. Di-4-ANEPPDHQ produces a fluorescence spectrum shift by changing the polarity of the lipid environment after embedding into the cell membrane, thereby quantifying the degree of lipid accumulation. The excitation wavelength of Di-4-ANEPPDHQ is 488 nm, and the emission wavelengths are 560 nm and 650 nm in the liquid ordered and disordered phases, respectively. Di-4-ANEPPDHQ is often used for fluorescence imaging studies of membrane microstructure, lipid order, and membrane tension response in living cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 797785-10-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-D1428. | |
| Di-4-ANEPPDHQ (solution) | Di-4-ANEPPDHQ (solution) is a polarity-sensitive membrane probe with a doubly positive charge that can be used to visualize membrane microdomains in living Arabidopsis cells. Di-4-ANEPPDHQ produces a fluorescence spectrum shift by changing the polarity of the lipid environment after embedding into the cell membrane, thereby quantifying the degree of lipid accumulation. The excitation wavelength of Di-4-ANEPPDHQ is 488 nm, and the emission wavelengths are 560 nm and 650 nm in the liquid ordered and disordered phases, respectively. Di-4-ANEPPDHQ is often used for fluorescence imaging studies of membrane microstructure, lipid order, and membrane tension response in living cells[1][2][3].Solvent and concentration: DMSO: 5 mM. Uses: Scientific research. Category: Signaling pathways. CAS No. 797785-10-5. Pack Sizes: 50 μL; 100 μL. Product ID: HY-DY1089. | |
| DI-591 | DI-591 is a potent, high-affinity and cell-permeable inhibitor of the DCN1-UBC12 interaction. DI-591 binds to DCN1 and DCN2 with Ki values of 12?nM and 10.4 nM, respectively and has no appreciable binding to DCN3, DCN4, and DCN5 proteins. DI-591 selectively inhibits neddylation of cullin 3 but has no or minimal effect on neddylation of other cullin family members[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2245887-38-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124602. | |
| DI-82 | DI-82 is a potent deoxycytidine kinase (dCK) inhibitor with an IC50app of 27.8 nM and Kiapp of 9.2 nM. DI-82 has antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1638148-50-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-136499. | |
| Di-8-ANEPPS | Di-8-ANEPPS is a naphthylstyryl voltage-sensitive dye, shifting both their fluorescence excitation and emission spectra upon changes in Vm. Uses: Scientific research. Category: Signaling pathways. CAS No. 157134-53-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-101891. | |
| diABZI-4 | diABZI-4 is a STING activator and broad-spectrum antiviral agent with immunostimulatory activity. diABZI-4 triggers the TBK1-IRF3 and NF-κB signaling cascades by inducing STING oligomerization, thereby promoting the production of type I/III interferons and various proinflammatory cytokines. diABZI-4 exhibits broad-spectrum antiviral activity and effectively inhibits the replication of influenza A virus, SARS-CoV-2, herpes simplex virus, and other viruses. diABZI-4 also activates lymphocytes and macrophages to provide significant pre- and post-exposure protection in viral disease models. diABZI-4 can be used to study COVID-19, respiratory viral infections, and related immunopathological mechanisms[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2138299-65-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-168034. | |
| diABZI-C2-NH2 | diABZI-C2-NH2, an active analogue containing a primary amine functionality, is a STING agonist[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2137975-93-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137320. | |
| diABZI STING agonist-1 | diABZI STING agonist-1 is a tautomerism of diABZI STING agonist-1 tautomerism (HY-112921). diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2138299-33-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112921A. | |
| diABZI STING agonist-1 (tautomerism) | diABZI STING agonist-1 tautomerism is a tautomerism of diABZI STING agonist-1 (HY-112921A). diABZI STING agonist-1 tautomerism is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2138498-18-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-112921. | |
| diABZI STING agonist-1 trihydrochloride | diABZI STING agonist-1 (trihydrochloride) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 2138299-34-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112921B. | |
| diABZI-V/C-DBCO | diABZI-V/C-DBCO is a STING agonist with an EC50 of 1.47 nM. diABZI-V/C-DBCO activates the STING pathway, induces the production of IFN-I, and stimulates the secretion of IFN-β. diABZI-V/C-DBCO serves as a substrate for cathepsin B, and releases active diABZI-amine via cathepsin B-mediated cleavage. In an orthotopic mouse model of breast cancer, diABZI-V/C-DBCO increases serum IFN-β levels and the frequency of granzyme B+ CD8+ T cells. diABZI-V/C-DBCO is applicable to research related to triple-negative breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3035557-60-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-162874. | |
| Diacetolol-d7 | Diacetolol-d7 is a deuterium labeled Diacetolol. Diacetolol is the major metabolite of Acebutolol. Diacetolol is a β-adrenoceptor blocking and anti-arrhythmic agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1346604-19-0. Pack Sizes: 1 mg. Product ID: HY-100635S. | |
| Diadenosine pentaphosphate pentasodium | Diadenosine pentaphosphate pentasodium is an agonist and negative modulator of the P2X1 receptor, an endogenous vasoactive purine dinucleotide that can be isolated from platelets. Diadenosine pentaphosphate pentasodium mediates negative regulation of dendrite growth and number by activating homologous and heterologous P2X1 receptors, which triggers a transient and moderate increase in intracellular calcium levels within dendritic growth cones. Diadenosine pentaphosphate pentasodium is widely present in secretory vesicles such as platelets, chromaffin cells and brain synaptosomes, and exhibits selective activity on dendrite growth of cultured hippocampal neurons, inhibiting only dendrite growth without affecting axon growth. Diadenosine pentaphosphate pentasodium has a weaker ability to compete with RcCHAD for binding to polyP than short-chain polyPs[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4097-4-5. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg. Product ID: HY-113273A. | |
| Diallate | Diallate is thiocarbamate herbicide. Diallate can produce mutagenic responses in the mouse lymphoma assay in the presence of metabolic activation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2303-16-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W774905. | |
| Diallyl Trisulfide | Diallyl Trisulfide is an orally active anticancer agent that can be isolated from garlic. Diallyl Trisulfide has the ability to induce apoptosis and exhibits anticancer, anti-inflammatory, antioxidant, and antibacterial activities. Diallyl Trisulfide can be used to study a variety of cancers, including liver, colon and prostate cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2050-87-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-117235. | |
| Diaminobiotin | Diaminobiotin is a biotin analog. Diaminobiotin can increase the transcriptional activity of IL-2 and IL-2R genes in Jurkat cells. Diaminobiotin does not affect the abundance of holocarboxylase and the activity of propionyl-CoA carboxylase in Jurkat cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 22342-46-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W048444. | |
| Dianemycin | Dianemycin (Nanchangmycin free acid), a polyether antibiotic produced by Streptomyces nanchangensis NS3226, inhibits gram-positive bacteria[1]. Nanchangmycin is a broad spectrum antiviral active against Zika virus[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Nanchangmycin free acid. CAS No. 35865-33-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-100528A. | |
| Dianicline dihydrochloride | Dianicline dihydrochloride is a α4β2 nicotinic acetylcholine receptor partial agonist, a class of agents that includes varenicline and cytisine for smoking cessation. Dianicline dihydrochloride increases cessation rates in a dose-dependent manner[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 292634-27-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-110241. | |
| Diazaborine | Diazaborine is an inhibitor for enoyl-acyl carrier protein (enoyl ACP) in an NAD+-dependent manner. Diazaborine exhibits antibacterial activity, MIC for E. coli and K. pneumoniae is 25 and 3.12 μg/mL[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 22959-81-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119749. | |
| Diaziquone | Diaziquone (NSC 182986), an aziridinylbenzoquinone, is a DNA alkylating agent. Diaziquone shows a broad antitumor activity against numerous transplantable murine tumors including curative activity against several intracerebrally implanted tumors. Diaziquone crosses the blood brain barrier[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 182986. CAS No. 57998-68-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-119969. | |
| DiAzKs hydrochloride | DiAzKs (H-L-Photo-lysine) hydrochloride is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs hydrochloride can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs hydrochloride acts as a UV light-activated photo-crosslinking probe[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: H-L-Photo-lysine hydrochloride. CAS No. 2421187-79-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0853A. | |
| Diazo Biotin-PEG3-alkyne | Diazo Biotin-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Diazo Biotin-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1884349-58-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-140925. | |
| Diazoxide | Diazoxide (Sch-6783) is an ATP-sensitive potassium channel activator, has the potential for hyperinsulinism treatment. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sch-6783; SRG-95213. CAS No. 364-98-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-B1140. | |
| Diazoxide (Standard) | Diazoxide (Standard) is the analytical standard of Diazoxide. This product is intended for research and analytical applications. Diazoxide (Sch-6783) is an ATP-sensitive potassium channel activator, has the potential for hyperinsulinism treatment. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sch-6783 (Standard); SRG-95213 (Standard). CAS No. 364-98-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1140R. | |
| DiBAC4(3) | DiBAC4(3) is a voltage-sensitive fluorescent dye (λex=490 nm, λem=505 nm). DiBAC4(3) can be used to measure cell membrane potential. Uses: Scientific research. Category: Signaling pathways. CAS No. 70363-83-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-101892. | |
| DiBAC4(5) | DiBaC4(5) is a fluorescent voltage-sensitive dye that can be used to monitor the transmembrane potentials when Papain-dissociated retinal cells from adult zebrafish were exposed to GABAergic ligands. DiBaC4(5) is a potential-sensitive fluorescence dye[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 63560-89-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D1092. | |
| DIBAC-GGFG-NH2CH2-Dxd | DIBAC-GGFG-NH2CH2-Dxd (compound LP4), a Camptothecin (HY-16560) derivative, is a linker-payload of protein-agent conjugates[1]. Dxd (HY-13631D) can be used as a payload for the antibody-coupling drug ADC (DS-8201a).DIBAC-GGFG-NH2CH2-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2758875-01-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147363. | |
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