BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| BO3482 | BO3482, a dithiocarbamate carbapenem, inhibits the growth of methicillin-resistant Staphylococci (MRS) (MIC90= 6.25 mg/mL) and has a dithiocarbamate chain at the C-2 position of 1beta-methyl-carbapenem. Synonyms: BO3482; BO 3482; BO-3482; (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-3-[2-hydroxyethyl(methyl)carbamothioyl]sulfanyl-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; sodium. CAS No. 198013-53-5. Molecular formula: C14H20N2NaO5S2. Mole weight: 383.44. |  |
| Bobcat339 hydrochloride | Bobcat339 is a selective cytosine-based TET enzyme inhibitor with IC50 of 33 μM and 73 μM for TET1 and TET2, respectively. It does not inhibit the DNA methyltransferase DNMT3a. Synonyms: Bobcat339 HCl. CAS No. 2436747-44-1. Molecular formula: C16H13Cl2N3O. Mole weight: 334.2. | |
| Boc5 | Boc5, a non-peptide glucagon-like peptide-1 (GLP-1R) receptor agonist. Synonyms: 1,3-Bis[[4-(Tert-Butoxy-Carbonylamino)Benzoyl]Amino]-2,4-Bis[3-Methoxy-4-(Thiophene-2-Carbonyloxy)-Phenyl]Cyclobutane-1,3-Dicarboxylic Acid. Grade: ≥98% by HPLC. CAS No. 917569-14-3. Molecular formula: C54H52N4O16S2. Mole weight: 1077.1. | |
| Boc-AEVD-CHO trifluoroacetate salt | Boc-AEVD-CHO is an inhibitor of caspase-8 (Ki = 1.6 nM) that also inhibits caspase-1, -3, -6, and -9 (Kis = <12, 42, 52, and 48 nM, respectively). It inhibits apoptosis induced by the aneugen nocodazole in isolated human peripheral blood mononuclear cells (PBMCs) at concentration of 300 μM. Synonyms: Boc-Ala-Glu-Val-Asp-CHO. Grade: ≥95%. Molecular formula: C22H36N4O10·xCF3COOH. Mole weight: 516.54. | |
| Boc-Baclofen | Boc-Baclofen is the protect form of Baclofen, which is a specific GABA-B receptor agonist with muscle relaxant effect. Synonyms: 4-((tert-butoxycarbonyl)amino)-3-(4-chlorophenyl)butanoic acid. Grade: 98%. CAS No. 78131-30-3. Molecular formula: C15H20ClNO4. Mole weight: 313.78. | |
| Boc-D-Pen(pMeBzl)-OH | Boc-D-Pen(pMeBzl)-OH is a derivative of D-Penicillamine, which is a penicillin metabolite used in the treatment of Wilson's disease, Cystinuria, Scleroderma and arsenic poisoning. Synonyms: D-Valine, N-[(1,1-dimethylethoxy)carbonyl]-3-[[(4-methylphenyl)methyl]thio]-; (S)-2-((tert-butoxycarbonyl)amino)-3-methyl-3-((4-methylbenzyl)thio)butanoic acid; Boc-D-Pen(Mbzl)-OH; N-α-t-Butoxycarbonyl-S-(p-methylbenzyl)-D-penicillamine; N-α-t-Butoxycarbonyl-S-(p-methylbenzyl)-β,β-dimethyl-D-cysteine; 3-[(4-Methylbenzyl)sulfanyl]-N-{[(2-methyl-2-propanyl)oxy]carbonyl}valine; Boc-S-4-methylbenzyl-D-penicillamine; Boc-β,β-Dimethyl-D-Cys(mbzl)-OH. Grade: 95%. CAS No. 115962-34-0. Molecular formula: C18H27NO4S. Mole weight: 353.48. | |
| Boceprevir | An NS3 serine protease inhibitor of hepatitis C virus, for the treatment of HCV infection. Synonyms: EBP 520; EBP-520; EBP520; SCH-503034; SCH503034; SCH 503034 trade name: Victrelis. Grade: 0.98. CAS No. 394730-60-0. Molecular formula: C27H45N5O5. Mole weight: 519.687. | |
| Boc-γ-L-Ser(Bn)-PNA-A(Z)-OH | Boc-γ-L-Ser(Bn)-PNA-A(Z)-OH is an esteemed compound extensively employed in the biomedical sector, harboring the capacity for diverse ailment research concerning cancer, neurological disorders and viral infections. Synonyms: Boc-Gamma-L-Ser(Bn)-PNA-A(Cbz)-OH; Glycine, N-[(2R)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-3-(phenylmethoxy)propyl]-N-[[6-[[(phenylmethoxy)carbonyl]amino]-9H-purin-9-yl]acetyl]-. CAS No. 909867-01-2. Molecular formula: C32H37N7O8. Mole weight: 647.69. | |
| Boc-γ-L-Ser(Bn)-PNA-C(Z)-OH | Boc-γ-L-Ser(Bn)-PNA-C(Z)-OH is an innovative biomedical compound, functioning as a peptide nucleic acid (PNA) monomer. This compound proves efficacious in gene therapy and the development of antisense drugs. Synonyms: Boc-Gamma-L-Ser(Bn)-PNA-C(Cbz)-OH; Glycine, N-[(2R)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-3-(phenylmethoxy)propyl]-N-[[2-oxo-4-[[(phenylmethoxy)carbonyl]amino]-1(2H)-pyrimidinyl]acetyl]-. CAS No. 909867-00-1. Molecular formula: C31H37N5O9. Mole weight: 623.66. | |
| Boc-γ-L-Ser(Bn)-PNA-G(Z)-OH | Boc-γ-L-Ser(Bn)-PNA-G(Z)-OH is an indispensable element in the biomedical realm, usecd in the study of maladies and contagions. Synonyms: Boc-Gamma-L-Ser(Bn)-PNA-G(Cbz)-OH; Glycine, N-[[1,6-dihydro-6-oxo-2-[[(phenylmethoxy)carbonyl]amino]-9H-purin-9-yl]acetyl]-N-[(2R)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-3-(phenylmethoxy)propyl]-. CAS No. 909866-99-5. Molecular formula: C32H37N7O9. Mole weight: 663.69. | |
| Boc-γ-L-Ser(Bn)-PNA-T-OH | Boc-γ-L-Ser(Bn)-PNA-T-OH is a biomedical compound, facilitating the development and adaptation of personalized oncological remedies, genetic disorder research and infectious ailment conques. Synonyms: Boc-Gamma-L-Ser(Bn)-PNA-T-OH; Glycine, N-[[3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl]acetyl]-N-[(2R)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-3-(phenylmethoxy)propyl]-. CAS No. 909866-98-4. Molecular formula: C24H32N4O8. Mole weight: 504.54. | |
| Bocidelpar | A modulator of peroxisome proliferator-activated receptor delta (PPAR-δ) that improves mitochondrial function. Synonyms: ASP0367; MA-0211; Hexanoic acid, 3-methyl-6-[2-[[5-methyl-2-[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl]methyl]phenoxy]-, (3R)-. Grade: 98%. CAS No. 2095128-20-2. Molecular formula: C25H27F3N2O3. Mole weight: 460.49. | |
| Boc-L-Ornithine Methyl Ester HCl | An impurity of L-ornithine, which has an antifatigue effect in increasing the efficiency of energy consumption and promoting the excretion of ammonia. Synonyms: Boc-L-Ornithine Methyl Ester HCl; methyl (2S)-5-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoate. Grade: > 95%. CAS No. 748150-93-8. Molecular formula: C11H22N2O4. HCl. Mole weight: 283.31. | |
| Bococizumab | Bococizumab is a humanized monoclonal antibody binding to proprotein convertase subtilisin/kexin type 9 (PCSK9), which reduces LDL cholesterol (LDL-C) levels. Bococizumab may be used as a potential drug for the treatment of hypercholesterolemia. Synonyms: PF-04950615; PF 04950615; PF04950615. CAS No. 1407495-02-6. | |
| Boc-Oxytocin | Boc-Oxytocin is an impurity of Oxytocin, which is a mammalian neurohypophysial hormone used as a vasodilator agent. Synonyms: tert-butyl ((4R,7S,10S,13S,16S,19R)-7-(2-amino-2-oxoethyl)-4-((S)-2-(((S)-1-((2-amino-2-oxoethyl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carbonyl)-10-(3-amino-3-oxopropyl)-13-((S)-sec-butyl)-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl)carbamate. CAS No. 6390-51-8. Molecular formula: C48H74N12O14S2. Mole weight: 1107.31. | |
| Boc-Saxagliptin | An impurity of saxagliptin. Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of type II diabetes. Synonyms: N-[(1S)-2-[(1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hex-2-yl]-1-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-2-oxoethyl]-Carbamic Acid 1,1-Dimethylethyl Ester; Saxagliptin Impurity 16. Grade: > 95%. CAS No. 709031-43-6. Molecular formula: C23H33N3O4. Mole weight: 415.54. | |
| Boc-Trp-Met-Asp-Phe-NH2 | Boc-Trp-Met-Asp-Phe-NH2 refers to Tetragastrin, which has been modified with a BOC (tert-Butyloxycarbonyl) group. The BOC group is a commonly used amino protecting group in organic synthesis, especially in peptide synthesis. Tetragastrin itself is the C-terminal tetrapeptide of gastrin, with the sequence H-Trp-Met-Asp-Phe-NH2. Tetragastrin stimulates gastric secretion and acts as a Cholecystokinin (CCK-4) receptor agonist. It is known for its gastric mucosal protective effects and is used to improve symptoms of hypochlorhydria or gastric atony, as well as in the treatment of atrophic gastritis. Synonyms: BOC-Tetragastrin; 4-7-Cholecystokinin-7 (swine), N-[(1,1-dimethylethoxy)carbonyl]-; Alaninamide, N-carboxy-L-tryptophyl-L-methionyl-L-aspartylphenyl-, N-tert-butyl ester, L-; N-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide; (tert-Butoxycarbonyl)tetragastrin; Boc-CCK-4; Boc-WMDF-NH2; N-tert-Butoxycarbonyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-phenylalaninamide. Grade: ≥95%. CAS No. 5235-21-2. Molecular formula: C34H44N6O8S. Mole weight: 696.81. | |
| BODIPY FL C12-galactocerebroside | BODIPY FL C12-galactocerebroside is an experimental compound, enabling the exploration of intricate phenomena regarding cell membrane dynamics and lipid trafficking. As an illuminating fluorogenic compound, it possesses the remarkable ability to precisely mark sphingolipids and glycosphingolipids. Synonyms: N-(4,4-Difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-3-dodecanoyl)sphingosyl 1-b-D-galactopyranoside; Boron, [5-[(3,5-dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-N-[(1S,2R,3E)-1-[(β-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecenyl]-1H-pyrrole-2-dodecanamidato]difluoro-, (T-4)-. CAS No. 217189-44-1. Molecular formula: C47H78BF2N3O8. Mole weight: 861.95. | |
| Bofelisimer | Bofelisimer is an immunomodulator. Synonyms: Nα-{[(2-ambo-2,3-dihydroxypropyl)sulfanyl]acetyl}-Nω-(2,5,8,11-tetraoxatridecan-13-yl)poly[N6-{[(2-ambo-2,3-dihydroxypropyl)sulfanyl]acetyl}-L-lysine-co-N6-{[(4-oxo-4-{[2-(4-{[3-O-(3-O-sulfo-β-D-glucopyranuronosyl)-β-D-galactopyranosyl]oxy}phenyl)ethyl]amino}butyl)sulfanyl]acetyl}-L-lysine (~0.65:0.35)]-ω-amide. CAS No. 2485035-32-1. Molecular formula: [(C11H20N2O4S)x(C32H47N3O18S2)y]n(C14H29NO7S). | |
| Bohemine | Bohemine, structurally similar to Olomoucine and Roscovitine, is a 2,6,9-trisubstituted purine derivative that inhibits cyclin-dependent kinases (CDKs) and exhibits anticancer activity. Synonyms: 3-[[6-(benzylamino)-9-propan-2-ylpurin-2-yl]amino]propan-1-ol; 6-benzylamino-2-(3-hydroxypropylamino)-9-isopropylpurine; bohemine. Grade: ≥97%. CAS No. 189232-42-6. Molecular formula: C18H24N6O. Mole weight: 340.42. | |
| Bola Sophorolipids | Bola sophorolipids are a type of glycolipid that feature a bolaamphiphilic structure, where the molecule has two hydrophobic tails connected by a hydrophilic sophorolipid head group. They are synthesized by certain yeast species and consist of a sophorose (a disaccharide) esterified with long-chain fatty acids. The bolaamphiphilic nature of bola sophorolipids gives them unique properties, such as the ability to self-assemble into micelles or vesicles, making them useful in various applications, including drug delivery, cosmetics, and as surfactants in industrial processes. Synonyms: 2b-O-b-D-glucopyranosyl-b-D-glucopyranosyl; 17-L-([2b-O-b-D-glucopyranosyl-b-D-glucopyranosyl]-oxy)-cis-9-octadecenoate. Molecular formula: C42H74O23. Mole weight: 947.02. | |
| Bombesin acetate | Bombesin is a neuropeptide with many biological effects such as hormone release, activation of pancreatic enzyme secretion, inhibition of gastric emptying, and modulation of gastric acid secretion. It binds to the gastrin-releasing peptide receptor (GRPR) in rat pancreatic acinar cells (Ki = 1.88 nM), and also to frog bombesin receptor subtype 4 (BB4) in CHO cells overexpressing the receptor (Ki = 1.7 nM). Synonyms: Bombesin, acetate (1:x); H-Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 acetate salt; L-pyroglutamyl-L-glutaminyl-L-arginyl-L-leucyl-glycyl-L-asparagyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valyl-glycyl-L-histidyl-L-leucyl-L-methioninamide acetate salt; Glp-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2.xCH3CO2H. Grade: ≥95%. CAS No. 1222319-87-0. Molecular formula: C71H110N24O18S.xC2H4O2. Mole weight: 1619.85 (free base). | |
| Bombinakinin-GAP | Bombinakinin-GAP is a bioactive bradykinin-related peptide that reduces 60% food intake following i.c.v. administration in rats. Synonyms: BOMBINAKININ-GAP; 573671-91-7; AKOS024457065; Bombinakinin M Gene Associated Peptide. CAS No. 573671-91-7. Molecular formula: C145H219N39O39S3. Mole weight: 3228.75. | |
| Bombinakinin M | Bombinakinin M is a potent bradykinin receptor agonist with selectivity for mammalian arterial smooth muscle bradykinin receptors, displaying ~ 50-fold greater potency than bradykinin. Synonyms: Maximakinin. CAS No. 509151-65-9. Molecular formula: C100H159N31O24. Mole weight: 2179.55. | |
| Bomedemstat | Bomedemstat, an orally active and irreversible lysine-specific histone demethylase 1 (LSD1) inhibitor with antineoplastic activity, can be used to study acute myeloid leukemia (AML), myelodysplastic syndrome, and myelofibrosis (MF). Synonyms: IMG-7289; Benzamide, N-((1S)-4-(((1R,2S)-2-(4-fluorophenyl)cyclopropyl)amino)-1-((4-methyl-1-piperazinyl)carbonyl)butyl)-4-(1H-1,2,3-triazol-1-yl)-; N-((S)-5-((1R,2S)-2-(4-fluorophenyl)cyclopropylamino)-1-(4-methylpiperazin-1-yl)-1-oxopentan-2-yl)-4-(1H-1,2,3-triazol-1-yl)benzamide. CAS No. 1990504-34-1. Molecular formula: C28H34FN7O2. Mole weight: 519.61. | |
| Bometolol Hydrochloride | Bometolol is a beta-adrenergic blocking drug. Synonyms: 5-[3-[2-(3,4-dimethoxyphenyl)ethylamino]-2-hydroxypropoxy]-8-(2-oxopropoxy)-3,4-dihydro-1H-quinolin-2-one; hydrochloride. CAS No. 65023-16-7. Molecular formula: C25H33ClN2O7. Mole weight: 508.99. | |
| BOMIN-1 | Synthetic, a selective irreversible inhibitor of carboxylesterases. Synonyms: 2-Ethoxy-3H-1,4,2lambda5-benzodioxaphosphinine 2-oxide. Grade: 95 % ( TLC). CAS No. 4081-22-5. Molecular formula: C9H11O4P. Mole weight: 214.16. | |
| BOMIN-2 | Synthetic, a selective irreversible inhibitor of carboxylesterases. Synonyms: 2-Propoxy-3H-1,4,2lambda5-benzodioxaphosphinine 2-oxide. Grade: 95 % (TLC). CAS No. 110606-96-7. Molecular formula: C10H13O4P. Mole weight: 228.18. | |
| BOMIN-3 | Synthetic, a selective irreversible inhibitor of carboxylesterases. Synonyms: 2-Butoxy-2-oxo-3H-1,4,2-benzodioxaphosphorine. Grade: 95 % (TLC). CAS No. 110606-97-8. Molecular formula: C11H15O4P. Mole weight: 242.21. | |
| Bonaphthone | Bonafton is an antiviral agent. Synonyms: 6-bromonaphthalene-1,2-dione; 6954-48-9; Bonaphthone; Bonafton; 6-Bromo-1,2-naphthoquinone; 6-BROMO-1,2-NAPHTHALENEDIONE; Bonaphthon; 1,2-Naphthalenedione, 6-bromo-; 1,2-NAPHTHOQUINONE, 6-BROMO-; 6-bromo-1,2-dihydronaphthalene-1,2-dione; TX6H0Q18AM; NSC-37564; 6-Brom-1,2-naphthochinon; NSC 37564; BRN 1944551; BROMNAPHTOQUINONE; UNII-TX6H0Q18AM; 4-07-00-02422 (Beilstein Handbook Reference); SCHEMBL2525185; CHEMBL4303595; DTXSID30219800; MXWZRRPNVLCHMY-UHFFFAOYSA-N; BDBM442806; BROMNAPHTOQUINONE [WHO-DD]; ALBB-014892; NSC37564; MFCD00464116; STK028617; AKOS001632647; HY-W269306; LS-04730; UA 13082; DB-317968; CS-0314608; EU-0038136; CS-004/04003052; BRD-K34149328-001-01-3; BRD-K34149328-001-02-1. Grade: ≥95%. CAS No. 6954-48-9. Molecular formula: C7H7NO2. Mole weight: 137.14. | |
| Bongkrekic acid | Bongkrekic acid is an acid-labile toxin produced by Pseudomonas cocoveneans. Uses: Anti-bacterial agents. Synonyms: (2E,4Z,6R,8Z,10E,14E,17S,18E,20Z)-20-(Carboxymethyl)-6-methoxy-2,5,17-trimethyl-2,4,8,10,14,18,20-docosaheptaenedioic Acid; (-)-Bongkrekic Acid; BA; Flavotoxin A. Grade: ≥98%. CAS No. 11076-19-0. Molecular formula: C28H38O7. Mole weight: 486.60. | |
| BoNT-IN-1 | BoNT-IN-1 is a potent inhibitor of Botulinum neurotoxin A light chain (IC50 = 0.9 uM). Uses: A potent inhibitor of botulinum neurotoxin a light chain. Synonyms: MDK-3033; MDK3033; MDK 3033; BoNT IN 1; BoNT-IN-1; BoNT Inhibitor 1; 2-Methyl-7-{[(4-methyl-2-pyridinyl)amino](2-nitrophenyl)methyl}-8-quinolinol. Grade: ≥95%. CAS No. 694443-03-3. Molecular formula: C23H20N4O3. Mole weight: 400.43. | |
| Bopindolol fumarate | Bopindolol fumarate is an orally active antagonist of β-adrenoceptors (ARs) with partial agonist activity. Bopindolol fumarate is also a prodrug of pindolol and can be used for essential and renovascular hypertension research. Synonyms: Sandonorm; (±)-Bopindolol fumarate. CAS No. 79125-22-7. Molecular formula: C27H32N2O7. Mole weight: 496.55. | |
| Bopindolol malonate | Bopindolol is a non-selective, potent and long-acting β-adrenergic receptor antagonist. It demonstrates inhibition of H2O2-induced lipid peroxdiation. Bopindolol malonate slowly dissociates into the active metabolites 4-(3-tert-butylamino-2-hydroxypropoxy)-2-methyl indole and 4-(3-tert-butylaminopropoxy)-2-carboxyl indole which both demonstrate potent β1-adrenoceptor blocking activity. Formulations containing bopindolol have been used to treat essential and renovascular hypertension. Uses: Adrenergic beta-antagonists. Synonyms: Bopindolol Malonate; AC1LCS45; SCHEMBL348872; CTK8F8315; HE393689; LS-120081; D01794; Wandonorm. Grade: ≥98%. CAS No. 82857-38-3. Molecular formula: C23H28N2O3·C3H4O4. Mole weight: 484.5. | |
| BOP sodium salt | BOP is a dual α9β1/α4β1 integrin inhibitor preferentially mobilizes HSCs and progenitors. Synonyms: N-(Benzenesulfonyl)-L-prolyl-L-O-(1-pyrrolidinylcarbonyl)tyrosine sodium salt. Grade: ≥98% by HPLC. CAS No. 1947348-42-6. Molecular formula: C25H28N3O7SNa. Mole weight: 537.56. | |
| Bornaprine | Bornaprine is an anticholinergic used as an antiparkinsonian agent. Uses: Muscarinic antagonists. Synonyms: 2-Phenylbicyclo[2.2.1]heptane-2-carboxylic acid 3-(diethylamino)propyl ester; 3-(Diethylamino)propyl 2-phenyl-2-norbornanecarboxylate; Sormodren. Grade: > 95%. CAS No. 20448-86-6. Molecular formula: C21H31NO2. Mole weight: 329.49. | |
| Boron Ascorbate | Boron Ascorbate is a biomedical compound commonly used in the research of arthritand other inflammatory conditions. It combines the benefits of boron and ascorbic acid, exhibiting antioxidant and anti-inflammatory properties. Synonyms: tris((R)-2-((S)-1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-yl) borate. Molecular formula: C18H21BO18. Mole weight: 536.16. | |
| Bortezomib-d15 | Bortezomib, sold under the brand name Velcade among others, is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma. Bortezomib is a dipeptide boronic acid derivative that reversibly inhibits the 20S proteasome with Ki of 0.6 nM. It binds the β5-subunit of the 20S proteasome and selectively inhibits chymotryptic activity. Bortezomib blocks the degradation of tumor-suppressing and proapoptotic proteins to induce cell cycle arrest and apoptosis in cancer cell lines. New studies show that bortezomib may potentially help recover from vincristine treatment in treating acute lymphoblastic leukemia, when replacing vincristine in the process. Synonyms: LDP-341-d5; MG-341-d5; PS-341-d5. Grade: ≥99% atom D. Molecular formula: C57H54D15B3N12O9. Mole weight: 1113.76. | |
| Bortezomib Impurity 10 | Bortezomib Impurity 10 is an impurity of bortezomib, a drug used in the biomedical industry for therapy purposes. Bortezomib is a potent anticancer drug mainly used in the therapy of multiple myeloma. Synonyms: 2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris-. Grade: > 95%. CAS No. 390800-88-1. Molecular formula: C57H69B3N12O9. Mole weight: 1098.69. | |
| Bortezomib Impurity 12 | Bortezomib Impurity 12 is an impurity of Bortezomib. Synonyms: (R)-Hydroperoxy Des(boric Acid) Bortezomib; N-((S)-1-(((R)-1-Hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide; 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1R)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-. Grade: > 95%. CAS No. 886979-78-8. Molecular formula: C19H24N4O4. Mole weight: 372.43. | |
| Bortezomib Impurity 13 | Bortezomib Impurity 13 is an impurity of Bortezomib, a pharmaceutical agent primarily indicated in the therapy of multiple myeloma and mantle cell lymphoma. Synonyms: 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-; N-((S)-1-(((S)-1-hydroperoxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide. Grade: > 95%. CAS No. 886979-81-3. Molecular formula: C19H24N4O4. Mole weight: 372.43. | |
| Bortezomib Impurity 4 | Bortezomib Impurity 4 is an impurity of Bortezomib. Synonyms: N(1-(3-Methylbutanamido) N(1-Des(boric Acid)) Bortezomib; (S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. Grade: > 95%. CAS No. 862894-96-0. Molecular formula: C19H22N4O3. Mole weight: 354.41. | |
| Bortezomib Impurity 7 | An impurity of Bortezomib. Bortezomib is a proteasome inhibitor primarily used in the treatment of multiple myeloma (MM) and mantle cell lymphoma (MCL). Synonyms: (R)-(3-Methyl-1-(pyrazine-2-carboxamido)butyl)boronic acid; Bortezomib Related Compound A. Grade: ≥95%. Molecular formula: C10H16BN3O3. Mole weight: 237.07. | |
| Bortezomib Impurity 9 | Bortezomib Impurity 9 is an impurity of Bortezomib and a tripeptide boronic acid proteasome inhibitor used as an antitumor agent. Synonyms: N-(2-Pyrazinylcarbonyl)-L-phenylalanyl-N-[(1R)-1-borono-3-methylbutyl]-L-phenylalaninamide ; ((R)-3-Methyl-1-((S)-3-phenyl-2-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanamido)butyl)boronic Acid. Grade: > 95%. CAS No. 1194235-41-0. Molecular formula: C28H34BN5O5. Mole weight: 531.42. | |
| Bortezomib Impurity B | Bortezomib Impurity B is used for the synthesis of Bortezomib. Synonyms: N-(2-pyrazinylcarbonyl)-L-phenylalanine; 3-Phenyl-2-[(pyrazine-2-carbonyl)amino]propionic Acid; (S)-3-Phenyl-2-(pyrazine-2-carbonylamino)propanoic Acid. Grade: 98% by HNMR. CAS No. 114457-94-2. Molecular formula: C14H13N3O3. Mole weight: 271.28. | |
| Bortezomib Impurity F | Bortezomib Impurity F is used for the synthesis of Bortezomib. Synonyms: 3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid Methyl Ester; N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester; N-(2-Pyrazinylcarbonyl)-L-phenylalanine Methyl Ester. Grade: > 95%. CAS No. 73058-37-4. Molecular formula: C15H15N3O3. Mole weight: 285.31. | |
| Bortezomib Impurity G | Bortezomib Impurity G is an impurity of the acclaimed drug Bortezomib, a drug tailored towards the affliction of multiple myeloma. Synonyms: (S)-Hydroxy Des(boric Acid) Bortezomib; N-[(1S)-2-[[(1S)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-Pyrazinecarboxamide. Grade: > 95%. CAS No. 289472-81-7. Molecular formula: C19H24N4O3. Mole weight: 356.43. | |
| Bortezomib Impurity H | Bortezomib Impurity H is an impurity of Bortezomib, a therapeutic agent for treating multiple myeloma and mantle cell lymphoma. Synonyms: (S)-N-(1-(isopentylaMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide. Grade: > 95%. CAS No. 1446194-56-4. Molecular formula: C19H24N4O2. Mole weight: 340.43. | |
| Bortezomib Impurity (R,R-Isomer) | Bortezomib Impurity (R,R-Isomer) is a diastereomer of Bortezomib. Synonyms: (1R,2R)-Bortezomib; B-[(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid; [(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid. Grade: 98% by HPLC. CAS No. 1132709-15-9. Molecular formula: C19H25BN4O4. Mole weight: 384.25. | |
| Bortezomib Impurity (R,S-Isomer) | Bortezomib Impurity (R,S-Isomer) is a diastereomer of Bortezomib. Synonyms: (1S,2R)-Bortezomib; B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid; N-(2-Pyrazinecarbonyl)-D-phenylalanine-D-leucine boronic anhydride. Grade: > 95%. CAS No. 1132709-16-0. Molecular formula: C19H25BN4O4. Mole weight: 384.25. | |
| Bortezomib Pinanediol Ester | Bortezomib-pinanediol is a prodrug of Bortezomib and a proteasome inhibitor. Synonyms: N-((S)-1-(((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide; (1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate; Bortezomib Pinanediol Impurity. Grade: 97+%. CAS No. 205393-22-2. Molecular formula: C29H39BN4O4. Mole weight: 518.46. | |
| Bortezomib USP Impurity G | Bortezomib USP Impurity G is an isomer of Bortezomib. It has been demonstrated to inhibit serine proteases shown to lower cellular Aβ concentrations, associated with Alzheimer's or hypertension. Synonyms: (1S,2S)-Bortezomib; ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid. Grade: 95%. CAS No. 1132709-14-8. Molecular formula: C19H25BN4O4. Mole weight: 384.243. | |
| Bortezomib USP Related Compoud B | Bortezomib USP Related Compoud B is an impurity of the acclaimed drug Bortezomib, which is a drug tailored towards the affliction of multiple myeloma. Synonyms: Bortezomib Amide Impurity; N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide; N-[(1S)-2-amino-2-oxo-1-(phenylmethyl)ethyl]pyrazinecarboxamide; (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. Grade: 98% by HPLC. CAS No. 289472-80-6. Molecular formula: C14H14N4O2. Mole weight: 270.29. | |
| Borussertib | Borussertib is a covalent-allosteric Akt inhibitor with IC50 of 0.8 nM. Borussertib displays antitumor activity in combination with the MEK inhibitor trametinib in patient-derived xenograft models and provides a starting point for further pharmacokinetic/dynamic optimization. CAS No. 1800070-77-2. Molecular formula: C36H32N6O3. Mole weight: 596.68. | |
| BOS172722 | BOS172722 is a potent and selective monopolar spindle 1 (MPS1) checkpoint inhibitor with IC50 of 11 nM. Synonyms: BOS-172722; BOS 172722; N2-(2-Ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine. CAS No. 1578245-44-9. Molecular formula: C24H30N8O. Mole weight: 446.55. | |
| Bosentan | Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively. Synonyms: Ro 47-0203. Grade: >98%. CAS No. 147536-97-8. Molecular formula: C27H29N5O6S. Mole weight: 551.61. | |
| Bosentan hydrate | Bosentan inhibits the presser response to big ET-1 both after i.v. and oral administration, with a long duration of action and no intrinsic agonist activity. Synonyms: Ro 47-0203; Ro 470203; Ro470203; Ro-470203. Grade: >98%. CAS No. 157212-55-0. Molecular formula: C27H29N5O6S.H2O. Mole weight: 569.63. | |
| Bosentan Impurity D | Bosentan Impurity D is an impurity of Bosentan. Synonyms: O-Deshydroxyethyl Bosentan; N-[1,6-Dihydro-5-(2-methoxyphenoxy)-6-oxo[2,2'-bipyrimidin]-4-yl]-4-(1,1-dimethylethyl)benzenesulfonamide; 4-tert-Butyl-N-[6-hydroxy-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide. Grade: > 95%. CAS No. 174227-14-6. Molecular formula: C25H25N5O5S. Mole weight: 507.57. | |
| Bosentan Related Compound 1 | Bosentan Related Compound 1 is an exquisite biomedical concoction used in the research of the complex ailment known as pulmonary arterial hypertension. Functioning as a highly discerning antagonist of the endothelin receptor, it proficiently curbs the constriction. Synonyms: 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine; Bosentan Related Compound D; 4,6-Dichloro-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)pyrimidine; Bosentan Related Compound D USP. Grade: > 95%. CAS No. 150728-13-5. Molecular formula: C15H10Cl2N4O2. Mole weight: 349.18. | |
| Bosentan Related Compound 2 | Bosentan Related Compound 2 is an intermediate as well as a degradation impurity of the endothelin receptor antagonist Bosentan. Synonyms: 4-tert-Butylbenzenesulfonamide; 4-(1,1-Dimethylethyl)benzenesulfonamide; p-tert-butyl-Benzenesulfonamide; NSC 9911. Grade: > 95%. CAS No. 6292-59-7. Molecular formula: C10H15NO2S. Mole weight: 213.30. | |
| Bosentan Related Compound 3 | Bosentan Related Compound 3 is an intermediate of Bosentan. Synonyms: N-[6-Chloro-5-(2-methoxyphenoxy)-(2,2-bipyrimidine)4-4-yl]-(1,1-dimethylethyl)-benzenesulfonamide; 4-tert-Butyl-N-[6-chloro-5-(2-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzeneSulfonamide. Grade: > 95%. CAS No. 150727-06-3. Molecular formula: C25H24ClN5O4S. Mole weight: 526.02. | |
| Bosentan Related Compound C | Bosentan Related Compound C is an impurity of Bosentan. Synonyms: N,N'-[1,2-Ethanediylbis[oxy[5-(2-methoxyphenoxy)[2,2'-bipyrimidine]-6,4-diyl]]]bis[4-(1,1-dimethylethyl)-benzenesulfonamide; 1,2-Bis({6-[4-(tert-butyl)phenylsulfonamido]-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl}oxy)ethane; Bosentan dimer. Grade: > 95%. CAS No. 1097263-60-9. Molecular formula: C52H52N10O10S2. Mole weight: 1041.18. | |
| Bosutinib | Bosutinib (SKI-606) is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM, respectively. Synonyms: 3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-; 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile; Bosulif; KIN 001-160; SK 606; SKI 606; SKI606; SK-I606. Grade: >98%. CAS No. 380843-75-4. Molecular formula: C26H29Cl2N5O3. Mole weight: 530.45. | |
| Bosutinib Isomer | Bosutinib Isomer is an isomer of Bosutinib. Synonyms: 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile; Bosutinib isomer 4; PF-06651481; PF-06651481-00. Grade: > 95%. CAS No. 1391063-17-4. Molecular formula: C26H29Cl2N5O3. Mole weight: 530.46. | |
| Bosutinib monohydrate | Bosutinib hydrate is a Src/Abl inhibitor used in the treatment of chronic myeloid leukemia (CML), a type of cancer that affects the blood and bone marrow. Bosutinib is a tyrosine kinase inhibitor that works by blocking the activity of BCR-ABL, a protein that promotes the growth of abnormal leukemia cells in patients with CML. BCR-ABL is formed as a result of a genetic abnormality known as the Philadelphia chromosome. It is indicated for the treatment of adults with newly diagnosed chronic phase CML as well as CML that is resistant or intolerant to prior therapy, including imatinib. Synonyms: Bosutinib hydrate; 3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-, hydrate (1:1); 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile hydrate; Bosulif hydrate; KIN 001-160 hydrate; SK 606 hydrate; SKI 606 hydrate. Grade: 98%. CAS No. 918639-08-4. Molecular formula: C26H29Cl2N5O3.H2O. Mole weight: 548.46. | |
| Bosutinib N-oxide | Bosutinib N-oxide is an impurity of Bosutinib, a BCR-ABL and src tyrosine kinase inhibitor used as an antineoplastic agent. Synonyms: 3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-4-oxido-1-piperazinyl)propoxy]-. Grade: 95%. CAS No. 2468737-96-2. Molecular formula: C26H29Cl2N5O4. Mole weight: 546.4. | |
| BP-1-102 | BP-1-102 is a potent and selective STAT3 inhibitor. BP-1-102 inhibits the expression of genes including c-Myc, Cyclin D1, Bcl-xL, Survivin, VEGF, and Krüppel-like factor 8, which is related to the STAT3-mediated breast tumor growth and migration. Synonyms: 4-(N-(4-cyclohexylbenzyl)-2-(2,3,4,5,6-pentafluoro-N-methylphenylsulfonamido)acetamido)-2-hydroxybenzoic acid. Grade: >98%. CAS No. 1334493-07-0. Molecular formula: C29H27F5N2O6S. Mole weight: 626.595. | |
| BP 554 | BP 554 is a selective 5-HT1A agonist. Synonyms: Piperazine, 1-[3-(1,3-benzodioxol-5-yloxy)propyl]-4-phenyl-; 1-(3-(Benzo[d][1,3]dioxol-5-yloxy)propyl)-4-phenylpiperazine; BP554; BP-554; LASSBio 670; 1-(3-(3,4-Methylenedioxyphenoxy)propyl)-4-phenylpiperzine. Grade: ≥95%. CAS No. 82900-57-0. Molecular formula: C20H24N2O3. Mole weight: 340.42. | |
| BP 554 maleate | BP 554 maleate is a selective 5-HT1A agonist. Synonyms: Piperazine, 1-[3-(1,3-benzodioxol-5-yloxy)propyl]-4-phenyl-, (2Z)-2-butenedioate (1:1); 1-(3-(Benzo[d][1,3]dioxol-5-yloxy)propyl)-4-phenylpiperazine maleate; 1-[3-(3,4-methylenedioxyphenoxy)propyl]-4-phenylpiperazine maleate. Grade: ≥99% by HPLC. CAS No. 1221401-95-1. Molecular formula: C20H24N2O3.C4H4O4. Mole weight: 456.48. | |
| BP 897 | BP 897, a potent and partial dopamine D3 receptor agonist and a weak D2 receptor antagonist, has a high affinity for the dopamine D3 receptor (Ki = 0.92 nM) and a 70 times lower affinity for the D2 receptor (Ki = 61 nM). It shows selective inhibition of cocaine-seeking behavior. Uses: Dopamine agonists. Synonyms: 2-Naphthalenecarboxamide, N-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-; BP-897; BP897; N-[4-(4-(2-Methoxyphenyl)piperazinyl)butyl]-2-naphthamide; N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide. CAS No. 192384-87-5. Molecular formula: C26H31N3O2. Mole weight: 417.54. | |
Our database is helping our users find suppliers everyday.
