MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Temtokibart | Temtokibart (ARGX-112) is a monoclonal antibody and also an IL-22RA1 inhibitor. Temtokibart inhibits the signal transduction of IL-22, IL-20 and IL-24. Temtokibart reduces the expression levels of inflammatory proteins, chemokines, immune cell migration and markers of activated immune pathways. Temtokibart improves the expression of genes related to immunity and epidermal barrier function. Temtokibart is applicable to research on moderate-to-severe atopic dermatitis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ARGX-112; LEO-138559; LP-0145. CAS No. 2639874-57-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990016. |  |
| Temuterkib | Temuterkib (LY3214996) is a highly selective inhibitor of ERK1 and ERK2, with IC50 of 5 nM for both enzymes in biochemical assays. Temuterkib potently inhibits cellular p-RSK1 in BRAF and RAS mutant cancer cell lines. Temuterkib shows potent antitumor activities in cancer models with MAPK pathway alterations. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY3214996. CAS No. 1951483-29-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101494. | |
| Tenapanor | Tenapanor (AZD1722) is a potent and orally active sodium/hydrogen exchanger isoform 3 (NHE3) inhibitor. Tenapanor reduces intestinal phosphate absorption predominantly through reduction of passive paracellular phosphate flux. Tenapanor has the potential for the research of hyperphosphatemia[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD1722; RDX5791. CAS No. 1234423-95-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15991. | |
| Tenapanor hydrochloride | Tenapanor (AZD1722) hydrochloride is a potent and orally active sodium/hydrogen exchanger isoform 3 (NHE3) inhibitor. Tenapanor hydrochloride reduces intestinal phosphate absorption predominantly through reduction of passive paracellular phosphate flux. Tenapanor hydrochloride has the potential for the research of hyperphosphatemia[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD1722 hydrochloride; RDX5791 hydrochloride. CAS No. 1234365-97-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15991A. | |
| Tenatoprazole | Tenatoprazole (TU-199) is an orally active imidazopyridine-based proton pump inhibitor with a prolonged plasma half-life. Tenatoprazole inhibits hog gastric H+/K+-ATPase activity with an IC50 of 6.2 μM. Tenatoprazole blocks the interaction of ubiquitin with the ESCRT-1 factor Tsg101, inhibits production of several enveloped viruses, including EBV[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TU-199. CAS No. 113712-98-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-17421. | |
| Teneligliptin | Teneligliptin (MP-513) hydrobromide hydrate is an orally active and selective dipeptidyl peptidase 4 (DPP-4) inhibitor (IC50s: 0.37 and 0.29 nM for the human and rat DPP-4, respectively). Teneligliptin hydrobromide hydrate improves blood glucose levels and can be used in researches related to type 2 diabetes mellitus[1][2][3][4][5][6][7][8]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MP-513. CAS No. 760937-92-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-14806. | |
| Teneliximab | Teneliximab (BMS-224819) is a chimeric monoclonal antibody, blocks the CD40-CD40L interaction. Teneliximab (BMS-224819) has partial agonist activity resulting in some signaling through CD40 and peripheral B cell depletion[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS 224819; Chi220; Anti-Human CD40 Recombinant Antibody. CAS No. 299423-37-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99321. | |
| Tenidap | Tenidap (CP-66248) is an orally active dual inhibitor of 5-LOX and COX with anti-inflammatory and immunomodulatory properties. Tenidap downregulates the expression of IL-1 receptors in chondrocytes, reduces the release of pro-inflammatory cytokines such as IL-1, IL-6 and TNF-α, and inhibits MMP production and cartilage degradation. Tenidap also blocks bone resorption and leukocyte adhesion to vascular endothelium, interferes with ion and pH changes associated with mouse sperm capacitation, and selectively enhances the activity of hKir2.3 channels (EC50=1.3 μM). Tenidap is applicable to research related to rheumatoid arthritis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP-66248. CAS No. 120210-48-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105028. | |
| Tenifatecan | Tenifatecan (SN2310) is an injectable emulsion composed of vitamin E, a succinate derivative,as well as 7-ethyl-10-hydroxycamptothecin (SN-38, the active metabolite of irinotecan). Tenifatecan (SN2310) possesses anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SN2310. CAS No. 850728-18-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14871. | |
| Teniposide | Teniposide is a podophyllotoxin derivative, acts as a topoisomerase II inhibitor, and used as a chemotherapeutic agent. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VM26. CAS No. 29767-20-2. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13761. | |
| Tenofovir | Tenofovir (GS 1278) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS 1278; PMPA. CAS No. 147127-20-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13910. | |
| Tenofovir alafenamide | Tenofovir alafenamide (GS-7340) is an investigational oral proagent of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS-7340. CAS No. 379270-37-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15232. | |
| Tenofovir alafenamide fumarate | Tenofovir alafenamide fumarate (GS-7340 fumarate) is an investigational oral proagent of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS-7340 fumarate. CAS No. 379270-38-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15232A. | |
| Tenofovir Disoproxil fumarate | Tenofovir Disoproxil fumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tenofovir DF; Bis(POC)-PMPA fumarate; GS 4331 fumarate. CAS No. 202138-50-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13782. | |
| Tenovin-6 | Tenovin-6, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC50s of 21 μM, 10 μM, and 67 μM, respectively. Tenovin-6 also inhibits dihydroorotate dehydrogenase (DHODH)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1011557-82-6. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15510. | |
| Tenovin-6 Hydrochloride | Tenovin-6 Hydrochloride, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 Hydrochloride inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC50s of 21 μM, 10 μM, and 67 μM, respectively. Tenovin-6 Hydrochloride also inhibits dihydroorotate dehydrogenase (DHODH)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1011301-29-3. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15510B. | |
| Tenuazonic acid | Tenuazonic acid is a nonhost-selective mycotoxin belonging to the tetramic acids family. Tenuazonic acid inhibits protein biosynthesis on ribosomes by suppressing the release of new protein. Tenuazonic acid is acutely toxic, and oral LD50 is set between 81-186 mg/kg in rats and mice. Tenuazonic acid blocks electron transport beyond the primary quinone receptor (QA) by interacting with the D1 protein and is a photosystem II (PSII) inhibitor. In addition, Tenuazonic acid has antiviral effects on measles virus, enterovirus, respiratory virus and so on. Tenuazonic acid has an inhibitory effect on skin cancer[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. CAS No. 610-88-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N6715. | |
| Tenuigenin | Tenuigenin is a major active component isolated from the root of the Chinese herb Polygala tenuifolia. Tenuigenin protects against S.aureus-induced pneumonia by inhibiting NF-κB activation. Tenuigenin has anti-inflammatory effect[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Senegenin. CAS No. 2469-34-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg. Product ID: HY-N0802. | |
| Tepilamide fumarate | Tepilamide fumarate (XP-23829; PPC-06) is an oral fumaric acid ester, acts as a proagent ofMonomethyl fumarate (HY-103252), and is used in the research of moderate to severe chronic plaque psoriasis. Tepilamide fumarate can enhance the effectiveness of oncolytic viruses[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XP-23829; PPC-06. CAS No. 1208229-58-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109105. | |
| Teplizumab | Teplizumab (MGA-031) is a Fc receptor non-binding anti-human CD3 monoclonal antibody. Teplizumab reduces the loss of beta-cell function. Teplizumab can be used in the research of type 1 diabetes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MGA-031; PRV-031. CAS No. 876387-05-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P99222. | |
| Tepoditamab | Tepoditamab (MCLA-117) is a full-length human IgG1 bispecific monoclonal antibody that binds to CLEC12A of myeloid cells and CD3 of cytotoxic T cells. Among others, CLEC12A is a myeloid differentiation antigen. Tepoditamab kills AML leukaemia mother cells and AML leukaemia stem cells, induces T cell-mediated proliferative lysis of AML cells. Tepoditamab induces upto 30-fold T-cell expansion. Tepoditamab results in moderate to strong cytokine (IFNγ, IL-6, IL-8, IL-10, and TNFα) and IFNγ release in human whole blood and PBMC, respectively. Tepoditamab can be used in acute myeloid leukaemia (AML) research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MCLA 117. CAS No. 2044679-53-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99390. | |
| Tepotinib | Tepotinib (EMD-1214063) is an orally active and highly selective, reversible, ATP-competitive c-Met inhibitor with an IC50 of 3 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib inhibits c-Met phosphorylation and induces autophagy. Tepotinib has antitumor effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EMD-1214063. CAS No. 1100598-32-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14721. | |
| Tepoxalin | Tepoxalin is an orally active dual inhibitor of Cyclooxygenase/Lipoxygenase, with IC50 values of 4.6 μM (sheep cyclooxygenase), 2.85 μM (rat cyclooxygenase), 0.15 μM (rat 5-lipoxygenase), and 3.0 μM (h12-lipoxygenase), respectively. Tepoxalin inhibits ROS production and NF-κB activation. Tepoxalin suppresses the production of thromboxane B2, leukotriene B4, prostaglandins and cytokines, and blocks platelet aggregation. Tepoxalin exhibits potent anti-inflammatory activity in rats with adjuvant-induced arthritis. Tepoxalin possesses analgesic activity. Tepoxalin shows no ulcerogenic activity within the anti-inflammatory dose range. Tepoxalin can be used in studies related to adjuvant-induced arthritis, skin inflammation and Alzheimer's disease[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 103475-41-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13219. | |
| TEPP-46 | TEPP-46 (ML-265) is a potent and selective pyruvate kinase M2 (PKM2) activator with an AC50 of 92 nM, showing little or no effect on PKM1, PKL and PKR[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ML-265. CAS No. 1221186-53-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-18657. | |
| Teprenone | Teprenone is an anti-ulcer agent, and works as an inducer of heat shock proteins (HSPs). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Geranylgeranylacetone. CAS No. 6809-52-5. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0779. | |
| Teprotumumab | Teprotumumab is an IGF-1 receptor (IGF-1R) blocking human monoclonal antibody. Teprotumumab binds to the ligand binding extracellular α-subunit domain of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab attenuates TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used for thyroid-associated ophthalmopathy research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1036734-93-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99165. | |
| Terameprocol | Terameprocol is an inhibitor targeting the Sp1 transcription factor, which can selectively inhibit the transcription of Sp1-dependent genes. Terameprocol exerts its effects by inhibiting Sp1-mediated gene transcription, such as reducing the expression of genes like CDC2, survivin and HMGB1, thereby arresting the cell cycle, inducing apoptosis, and suppressing the inflammatory response. Terameprocol exhibits anti-proliferative, pro-apoptotic, and anti-inflammatory activities and is currently mainly used in the research of diseases such as cancer and pulmonary arterial hypertension[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EM-1421. CAS No. 24150-24-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10447. | |
| Terazosin | Terazosin is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist. Terazosin works by relaxing blood vessels and the opening of the bladder. Terazosin has the potential for benign prostatic hyperplasia (BPH) and high blood pressure treatment[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 63590-64-7. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0371. | |
| Terbinafine | Terbinafine (TDT 067) is an orally active and potent antifungal agent. Terbinafine is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria[1][2][3]. Terbinafine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TDT 067. CAS No. 91161-71-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg. Product ID: HY-17395A. | |
| Terbinafine hydrochloride | Terbinafine hydrochloride (TDT 067 hydrochloride) is an orally active and potent antifungal agent. Terbinafine hydrochloride is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine hydrochloride also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria[1][2][3]. Terbinafine hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TDT 067 hydrochloride. CAS No. 78628-80-5. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-17395. | |
| Terbutaline | Terbutaline is an orally active β2-adrenergic receptor agonist and an active metabolite of bambuterol[1]. Terbutaline can be used in asthma symptom research[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 23031-25-6. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0802A. | |
| Terbutaline sulfate | Terbutaline sulfate is an orally active β2-adrenergic receptor agonist and an active metabolite of bambuterol[1]. Terbutaline sulfate can be used in asthma symptom research[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Terbutaline hemisulfate. CAS No. 23031-32-5. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B0802. | |
| Terbuthylazine-d9 | Terbuthylazine-d9 is the deuterium labeled Terbuthylazine (HY-B1847). Terbuthylazine is an inhibitor of acetolactate syntase (ALS), is a selective herbicide. Terbuthylazine blocks electron transport in photosystem II via interaction with the D1-protein. Uses: Scientific research. Category: Signaling pathways. CAS No. 1346602-52-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B1847S. | |
| Terbuthylazine (Standard) | Terbuthylazine (Standard) is the analytical standard of Terbuthylazine (HY-B1847). This product is intended for research and analytical applications. Terbuthylazine is an inhibitor of acetolactate syntase (ALS), is a selective herbicide. Terbuthylazine blocks electron transport in photosystem II via interaction with the D1-protein. Uses: Scientific research. Category: Signaling pathways. CAS No. 5915-41-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1847R. | |
| Terevalefim | Terevalefim (ANG-3777), an hepatocyte growth factor (HGF) mimetic, selectively activates the c-Met receptor[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ANG-3777. CAS No. 1070881-42-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137455. | |
| Terfenadine | Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM[1]. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Terfenadine; MDL-991. CAS No. 50679-08-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-B1193. | |
| Teriflunomide | Teriflunomide is the active metabolite of leflunomide, an approved therapy for rheumatoid arthritis. It inhibits pyrimidine synthesis and therefore potently decreases T cell and B cell proliferation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: A77 1726. CAS No. 163451-81-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-15405. | |
| Teriparatide | Teriparatide (Human parathyroid hormone-(1-34)) is a PTH1 receptor agonist. Teriparatide (Human parathyroid hormone-(1-34)) can be used for osteoporosis research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Human parathyroid hormone-(1-34); hPTH (1-34). CAS No. 52232-67-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0059. | |
| Terizidone | Terizidone is an antibacterial agent, and shows bacteriostatic activity. Terizidone can be used in tuberculosis (TB) research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25683-71-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-112324. | |
| Terlipressin diacetate | Terlipressin diacetate is a vasopressin analogue with potent vasoactive properties. Terlipressin diacetate is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin diacetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin diacetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1884420-36-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12554A. | |
| Terminolic acid | Terminolic acid is a pentacyclic triterpene glycoside and antibacterial agent. Terminolic acid can be isolated from Combretum racemosum. Terminolic acid inhibits proinflammatory cytokines by binding to the receptor active sites of IL-1β and IL-6. Terminolic acid reduces IL-8. Terminolic acid has antibacterial activity against Staphylococcus aureus, Escherichia coli and Enterococcus faecalis with MICs ranging from 64 to 256 μg/mL. Terminolic acid is used in colon cancer research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 564-13-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N7652. | |
| Teropavimab | Teropavimab (3BNC117-LS) is a neutralizing antibody against HIV-1. Teropavimab can be used for the research of HIV infection[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3BNC117-LS; GS-5423. CAS No. 2417213-72-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99564. | |
| Terphenyllin | Terphenyllin is a naturally abundant p-terphenyl metabolite isolated from the coral derived fungus Aspergillus candidus, has signi?cant α-glucosidase inhibitory activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 52452-60-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-119821. | |
| Tersolisib | STX-478 (compound 80) is an oral CNS-penetrant allosteric mutant-selective PI3Kα inhibitor. STX-478 shows robust and durable tumor regression and can be used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: STX-478; STX-478-101; LY4064809. CAS No. 2883540-92-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156681. | |
| TERT activator-1 | TERT activator-1 is a small molecule activator of telomerase reverse transcriptase (TERT). TERT activator-1 promotes TERT transcription through the MEK/ERK/AP-1 signaling cascade. TERT activator-1 promotes adult neurogenesis and enhances neuromuscular function. TERT activator-1 reduces cellular senescence and systemic inflammation in aged mice, and can be used in the study of aging[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 666699-46-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-402361. | |
| tert-Butyl (10-aminodecyl)carbamate | tert-Butyl (10-aminodecyl) carbamate (1-Boc-1,10-diaminodecane) is a synthetic intermediate that serves as a PROTAC linker in PROTAC synthesis and other conjugation applications. tert-Butyl (10-aminodecyl) carbamate is an alkane chain with a terminal amine and a Boc-protected amino group. The amine group can react with carboxylic acids, active NHS esters, carbonyl groups (ketones, aldehydes), etc. The Boc group can be deprotected under mild acidic conditions to form a free amine[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-Boc-1,10-diaminodecane. CAS No. 216961-61-4. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-W047688. | |
| tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate | tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate is a PROTAC linker. tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate can be used in the synthesis of PROTAC ER Degrader-12 (HY-160264) and PROTAC AR Degrader-9 (HY-170332)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 236406-55-6. Pack Sizes: 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-30756. | |
| tert-Butyl 2-azaspiro[3.3]heptan-6-ylcarbamate | tert-Butyl 2-azaspiro[3.3]heptan-6-ylcarbamate is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 1118786-85-8. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-20239. | |
| tert-Butyl 2-bromo-7-azaspiro[3.5]nonane-7-carboxylate | tert-Butyl 2-bromo-7-azaspiro[3.5]nonane-7-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 1225276-07-2. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W056572. | |
| tert-Butyl 2-hydroxy-7-azaspiro[3.5]nonane-7-carboxylate | tert-Butyl 2-hydroxy-7-azaspiro[3.5]nonane-7-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 240401-28-9. Pack Sizes: 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W052528. | |
| tert-Butyl 2-(piperidin-4-yl)acetate | tert-Butyl 2-(piperidin-4-yl)acetate is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 180182-07-4. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W067830. | |
| tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate | tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate is a drug intermediate for synthesis of various active compounds. Uses: Scientific research. Category: Signaling pathways. CAS No. 173405-78-2. Pack Sizes: 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-30536. | |
| tert-Butyl 4-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylate | tert-Butyl 4-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 1425970-61-1. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W059361. | |
| tert-Butyl 4-(bromomethyl)benzylcarbamate | tert-Butyl 4-(bromomethyl)benzylcarbamate is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 187283-17-6. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W018070. | |
| tert-Butyl 4-formylpiperidine-1-carboxylate | tert-Butyl 4-formylpiperidine-1-carboxylate is a PROTAC linker and can be used in the synthesis of PROTAC BRM/BRG1 degrader-3 (HY-168251)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 137076-22-3. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-69260. | |
| tert-Butyl 4-(hydroxymethyl)benzylcarbamate | tert-Butyl 4-(hydroxymethyl)benzylcarbamate is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 123986-64-1. Pack Sizes: 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W046402. | |
| tert-butyl (5-bromopentyl)carbamate | tert-butyl (5-bromopentyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 83948-54-3. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-77483. | |
| tert-Butyl 6-(aminomethyl)-2-azaspiro[3.3]heptane-2-carboxylate | tert-Butyl 6-(aminomethyl)-2-azaspiro[3.3]heptane-2-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 1363380-79-3. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W056320. | |
| tert-Butyl 6-formyl-2-azaspiro[3.3]heptane-2-carboxylate | tert-Butyl 6-formyl-2-azaspiro[3.3]heptane-2-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 1440960-67-7. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W056306. | |
| tert-Butyl (6-hydroxyspiro[3.3]heptan-2-yl)carbamate | tert-Butyl (6-hydroxyspiro[3.3]heptan-2-yl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 1000933-99-2. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-34928. | |
| tert-Butyl (8-aminooctyl)carbamate | tert-Butyl (8-aminooctyl)carbamate (1-Boc-1,8-diaminooctane) can be used as a PROTAC linker in the synthesis of PROTACs. tert-butyl (8-aminooctyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-Boc-1,8-diaminooctane. CAS No. 88829-82-7. Pack Sizes: 1 g; 5 g. Product ID: HY-42773. | |
| tert-Butyl 9-amino-3-azaspiro[5.5]undecane-3-carboxylate | tert-Butyl 9-amino-3-azaspiro[5.5]undecane-3-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 1272758-41-4. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W056269. | |
| tert-Butyl cis-4-(hydroxymethyl)cyclohexylcarbamate | tert-Butyl cis-4-(hydroxymethyl)cyclohexylcarbamate is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 223131-01-9. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W063916. | |
| tert-Butyl-DCL | Tert-Butyl-DCL is a PSMA inhibitor. Tert-Butyl-DCL Tert-Butyl-DCL can be used in the research of prostate cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (OtBu)KuE(OtBu)2. CAS No. 1025796-31-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W054292. | |
| tert-Butyl-hexanedioic acid | tert-Butyl-hexanedioic acid is a PROTAC linker. tert-Butyl-hexanedioic acid can be used to synthesize PROTAC molecules, such as PROTAC ERα Degrader-12 (HY-174453)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 52221-07-5. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W088749. | |
| tert-Butyl oct-7-yn-1-ylcarbamate | tert-Butyl oct-7-yn-1-ylcarbamate (N-Boc-oct-7-yn-1-amine) is crosslinker consisting of a propargyl group and a t-Boc protected amine group. The propargyl group reacts with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry reactions. The t-Boc protected amine can be deprotected under mild acidic conditions. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Boc-oct-7-yn-1-amine. CAS No. 1451262-84-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W575291. | |
| tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d8 | tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d8 is the deuterium labeled tert-Butyl piperazine-1-carboxylate[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Boc-piperazine-d8. CAS No. 1126621-86-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg. Product ID: HY-W454945S. | |
| tert-Butyl (trans-4-(hydroxymethyl)cyclohexyl)carbamate | tert-Butyl (trans-4-(hydroxymethyl)cyclohexyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 239074-29-4. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W056082. | |
| Tertiapin-Q | Tertiapin-Q is a highly selective blocker of GIRK1/4 heterodimer and ROMK1 (Kir1.1). Uses: Scientific research. Category: Signaling pathways. CAS No. 910044-56-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1275. | |
| Terutroban sodium | Terutroban (S-18886) sodium is a selective and orally active thromboxane-prostaglandin (TP) receptor antagonist with an IC50 of 16.4 nM. Terutroban sodium inhibits TXA2 and prostaglandin endoperoxide receptors. Terutroban sodium is a potent antithrombotic agent and possesses anti-atherosclerotic and anti-vasoconstrictor properties[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S-18886 sodium. CAS No. 609340-89-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16991A. | |
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