MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Cinrebafusp alfa | Cinrebafusp alfa (PRS 343) is a high affinity CD137/HER2 bispecfic anticalin-based drug. Cinrebafusp alfa binds to recombinant human HER2 (Kd=0.3 nM) and human monomeric CD137 (4-1BB; Kd=5 nM). Cinrebafusp alfa facilitates T-cell costimulation by tumor-localized, HER2-dependent 4-1BB clustering and activation, further enhancing T-cell receptor-mediated activity and leading to tumor destruction. Cinrebafusp alfa has the potential for HER2+ solid tumors research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PRS 343. CAS No. 2218515-90-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99605. |  |
| Cinromide | Cinromide is an anticonvulsant agent. Cinromide inhibits epithelial neutral amino acid transporter B0AT1 (SLC6A19) with an IC50 of 0.5 μM[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: trans-3-Bromo-N-ethylcinnamamide. CAS No. 58473-74-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-B1274. | |
| Cintirorgon | Cintirorgon (LYC-55716) is a first-in-class, selective and orally bioavailable RORγ agonist. Cintirorgon (LYC-55716) modulates gene expression of RORγ expressing T lymphocyte immune cells, resulting in enhanced effector function, as well as decreased immunosuppression, resulting in decreased tumor growth, and improved survival[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LYC-55716. CAS No. 2055536-64-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104037. | |
| Cipargamin | Cipargamin (NITD609) is an potent antimalarial compound, with an IC50 of appr 1 nM against P. falciparum. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NITD609; KAE609. CAS No. 1193314-23-6. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14430. | |
| Cipepofol | Cipepofol (Ciprofol), a novel 2,6-disubstituted phenol derivative, is a positive allosteric modulator and direct agonist of the GABAA receptor. Cipepofol can cause the central nerve inhibition and promote sleep based on the structural modification of Propofol (HY-B0649). Cipepofol can activate the sirtuin1 (Sirt1)/Nrf2 pathway. Cipepofol protects the heart against Isoproterenol (ISO; HY-B0468)-induced myocardial infarction by reducing cardiac oxidative stress, inflammatory response and cardiomyocyte apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ciprofol; HSK3486. CAS No. 1637741-58-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116152. | |
| Ciprofloxacin | Ciprofloxacin (Bay-09867) is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin has anti-proliferative activity and induces apoptosis. Ciprofloxacin is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bay-09867. CAS No. 85721-33-1. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-B0356. | |
| Ciprofloxacin-13C3,15N monohydrochloride | Ciprofloxacin-13C3,15N (Bay-09867-13C3,15N) monohydrochloride is 13C- and 15N-labeled Ciprofloxacin (monohydrochloride) (HY-B0356A)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bay-09867-13C3,15N monohydrochloride. CAS No. 2483830-12-0. Pack Sizes: 1 mg. Product ID: HY-B0356AS1. | |
| Ciprofloxacin-d8 hydrochloride | Ciprofloxacin-d8 (hydrochloride) is the deuterium labeled Ciprofloxacin. Ciprofloxacin (Bay-09867) hydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bay-09867-d8 hydrochloride. CAS No. 1216659-54-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0356S. | |
| Ciprofloxacin hydrochloride monohydrate | Ciprofloxacin (Bay-09867) hydrochloride monohydrate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin hydrochloride monohydrate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin hydrochloride monohydrate has anti-proliferative activity and induces apoptosis. Ciprofloxacin hydrochloride monohydrate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bay-09867 hydrochloride monohydrate. CAS No. 86393-32-0. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-B0356B. | |
| Ciprofloxacin monohydrochloride | Ciprofloxacin (Bay-09867) monohydrochloride is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin monohydrochloride induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin monohydrochloride has anti-proliferative activity and induces apoptosis. Ciprofloxacin monohydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bay-09867 monohydrochloride. CAS No. 93107-08-5. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-B0356A. | |
| Ciprofloxacin (Standard) | Ciprofloxacin (Standard) is the analytical standard of Ciprofloxacin. This product is intended for research and analytical applications. Ciprofloxacin (Bay-09867) is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin has anti-proliferative activity and induces apoptosis. Ciprofloxacin is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bay-09867 (Standard). CAS No. 85721-33-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B0356R. | |
| Cirazoline hydrochloride | Cirazoline hydrochloride (LD 3098 hydrochloride) is a potent competitive full α1A-adrenergic receptor (α1A-AR) agonist (Ki=120 nM) and only a partial agonist at α1B-AR (Ki= 960 nM) and α1D-AR (Ki=660 nM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LD 3098 hydrochloride. CAS No. 40600-13-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101300. | |
| Cirsilineol | Cirsilineol, a natural flavone compound, selectively inhibits IFN-γ/STAT1/T-bet signaling in intestinal CD4+ T cells. Cirsilineol has potent immunosuppressive and anti-tumor properties. Cirsilineol significantly ameliorates trinitro-benzene sulfonic acid (TNBS)-induced T-cell-mediated experimental colitis in mice[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 41365-32-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-119347. | |
| Cirsiliol | Cirsiliol is a potent and selective 5-lipoxygenase inhibitor and a competitive low affinity benzodiazepine receptor ligand. Uses: Scientific research. Category: Signaling pathways. CAS No. 34334-69-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110399. | |
| Cirsimaritin | Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors, with antidepressant, anxiolytic and antinociceptive activities. Uses: Scientific research. Category: Signaling pathways. CAS No. 6601-62-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N6648. | |
| Cirsiumaldehyde | Cirsiumaldehyde can be isolated from the roots of Anemone altaica[1]. Uses: Scientific research. Category: Natural products. CAS No. 7389-38-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W357642. | |
| Cirtociclib | Cirtociclib (BLU-222) is an orally active and highly selective CDK2 inhibitor. Cirtociclib disrupts Rb signaling and causes G1 arrest and apoptosis in CCNE1-amplified endometrial cancer cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BLU-222. CAS No. 2888704-84-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160701. | |
| Cirtuvivint | Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor. Cirtuvivint can be used for solid tumors research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SM08502. CAS No. 2143917-62-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137435. | |
| cis-5-Dodecenoic acid | cis-5-Dodecenoic acid is an inhibitor of COX-I and COX-II with anti-inflammatory activity. cis-5-Dodecenoic acid reduces prostaglandin synthesis by inhibiting COX enzyme activity and is involved in the fatty acid -β oxidative metabolic pathway. The metabolic rate of cis-5-Dodecenoic acid is significantly lower than that of saturated fatty acids. cis-5-Dodecenoic acid can be used in the research of anti-inflammation, fatty acid metabolism mechanisms and related physiological and pathological processes[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2430-94-6. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-N8469. | |
| cis-7,10,13,16-Docosatetraenoic acid methyl ester | cis-7,10,13,16-Docosatetraenoic acid methyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 13487-42-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W127370. | |
| (+)-cis-Abienol | (+)-cis-Abienol (Compound Z-abienol), a diterpenoid, can be isolated from leaves of tobacco. (+)-cis-Abienol inhibits hyphal growth of P. nicotianae[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (Z)-Abienol. CAS No. 17990-16-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-121999. | |
| Cisapride | Cisapride (R 51619) is an orally active 5-HT4 receptor agonist with an EC50 value of 140 nM. Cisapride is a hERG blocker with an IC50 value of 9.4 nM. Cisapride is a gastroprokinetic agent that stimulates gastrointestinal motor activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R 51619; (±)-Cisaprid. CAS No. 81098-60-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14149. | |
| Cisatracurium besylate | Cisatracurium besylate (51W89) is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 51W89 besylate; Cisatracurium besilate. CAS No. 96946-42-8. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg. Product ID: HY-13596. | |
| cis,cis-Muconic acid | cis,cis-Muconic acid is a dicarboxylic acid produced by Saccharomyces cerevisiae. cis,cis-Muconic acid shows pH-dependent toxicity against Saccharomyces cerevisiae CEN.PK113-7D. cis,cis-Muconic acid can be used as intermediate for the production of various plastics and polymers[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1119-72-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-W000800. | |
| cis-Epoxysuccinic acid | cis-Epoxysuccinic acid is a succinate receptor (SUCNR1/GPR91) agonist. cis-Epoxysuccinic acid inhibits cAMP levels with an EC50 value of 2.7 μM. cis-Epoxysuccinic acid can be used for the research of cardiovascular system[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 16533-72-5. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-125791. | |
| cis-MZ 1 | cis-MZ 1 is a cis isomer of meso-zeaxanthin, a xanthophyll carotenoid component of total zeaxanthin measured in serum and egg yolks.cis-MZ 1 is a triphenyltin benzoate that adopts either a tetrahedral monomeric structure (I) or a trans-SnR3O2 polymeric structure (III), with structure determined by a balance of steric and electronic factors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1797406-72-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-107425A. | |
| Cisplatin | Cisplatin (CDDP) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy[1][2][3]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: cis-Platinum; CDDP; cis-Diaminodichloroplatinum. CAS No. 15663-27-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-17394. | |
| cis-Tonghaosu | cis-Tonghaosu is one of the chemical components of German chamomile (Matricaria chamomilla L.) essential oil[1]. Uses: Scientific research. Category: Natural products. CAS No. 4575-53-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N12732. | |
| Citalopram | Citalopram is a racemate mixture of the active S(+)-enantiomer (Escitalopram; HY-14258) and R(-)-enantiomer. Citalopram is an orally active selective serotonin reuptake inhibitor (SSRI). Citalopram is an antidepressant and enhances serotoninergic neurotransmission[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 59729-33-8. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-121203. | |
| Citalopram hydrobromide | Citalopram hydrobromide is a selective serotonin reuptake inhibitor (SSRI), with blood-brain barrier permeability. Citalopram hydrobromide inhibits 5-HT uptake into synaptosomes with an IC50 of 1.8 nM. Citalopram hydrobromideinhibits the 5-HT uptake in rabbit blood platelets with an IC50 of 14 nM. Antidepressant effect[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Citalopram hydrobromide; Lu 10-171. CAS No. 59729-32-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1287. | |
| Citarinostat | Citarinostat (ACY241) is a second generation potent, orally active and high-selective HDAC6 inhibitor with an IC50 of 2.6 nM (IC50s of 35 nM, 45 nM, 46 nM and 137 nM for HDAC1, HDAC2, HDAC3 and HDAC8, respectively). Citarinostat has anticancer effects[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACY241. CAS No. 1316215-12-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15994. | |
| CITCO | CITCO, an imidazothiazole derivative, is a selective Constitutive androstane receptor (CAR) agonist. CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49?nM over pregnane X receptor (PXR), and no activity on other nuclear receptors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 338404-52-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103244. | |
| Citicoline | Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline inhibits reactive oxygen species (ROS) and apoptosis. Citicoline can be used for neurological disease and hearing loss study[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cytidine diphosphate-choline; CDP-Choline; Cytidine 5'-diphosphocholine. CAS No. 987-78-0. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B0739. | |
| Citicoline sodium | Citicoline sodium is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline sodium inhibits reactive oxygen species (ROS) and apoptosis. Citicoline sodium can be used for neurological disease and hearing loss study[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cytidine diphosphate-choline sodium; CDP-Choline sodium; Cytidine 5'-diphosphocholine sodium. CAS No. 33818-15-4. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg. Product ID: HY-B0739A. | |
| Citicoline (Standard) | Citicoline (Cytidine diphosphate-choline) (Standard) is the analytical standard of Citicoline. This product is intended for research and analytical applications. Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline inhibits reactive oxygen species (ROS) and apoptosis. Citicoline can be used for neurological disease and hearing loss study. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cytidine diphosphate-choline (Standard); CDP-Choline (Standard); Cytidine 5'-diphosphocholine (Standard). CAS No. 987-78-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0739R. | |
| Citraconic acid | Citraconic acid (Methylmaleic acid) is an orally active inhibitor targeting the NLRP3 inflammasome and Keap1-Nrf2 pathway. Citraconic acid reduces reactive oxygen species (ROS) generation by inhibiting succinate dehydrogenase (SDH) activity. Citraconic acid also modifies the conformation of Keap1 protein, relieves its inhibition of Nrf2, promotes antioxidant gene expression, and inhibits NLRP3 activation and the release of pro-inflammatory factors such as IL-1β and IL-18. Citraconic acid has anti-inflammatory and antioxidant activities, can reduce oxidative stress and cell pyroptosis, improve tissue damage, and can be used for the research of inflammation-related diseases such as acute renal ischemia-reperfusion injury. Citraconic acid is an isomer of Itaconic acid (HY-Y052)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Methylmaleic acid. CAS No. 498-23-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 5 g; 10 g; 25 g; 50 g. Product ID: HY-113298. | |
| Citral | Citral is an orally active monoterpene compound in lemon grass essential oil and a natural ALDH1A inhibitor, which can induce apoptosis and cycle arrest in breast cancer cell lines, and has analgesic, anti-injurious and anti-inflammatory effects[2][3]. Uses: Scientific research. Category: Induced disease models products. CAS No. 5392-40-5. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-N7083. | |
| Citrate synthase | Citrate synthase is responsible for catalyzing the first reaction of the citric acid cycle: the condensation of acetyl-CoA and oxaloacetate to form citrate. Citrate synthase is localized within eukaryotic cells in the mitochondrial matrix[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9027-96-7. Pack Sizes: 250 U; 500 U; 1000 U. Product ID: HY-P2739. | |
| Citreorosein | Citreorosein is a natural product that can be isolated from Xanthoria parietina[1]. Uses: Scientific research. Category: Natural products. Alternative Names: ω-Hydroxyemodin; NSC 624612. CAS No. 481-73-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N3592. | |
| Citric acid | Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 77-92-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg; 1 g; 2 g; 5 g. Product ID: HY-N1428. | |
| Citric acid-13C6 | Citric acid-13C6 is the 13C-labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 287389-42-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N1428S1. | |
| Citric acid-d4 | Citric acid-d4 is the deuterium labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 147664-83-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1428S. | |
| Citric acid monohydrate | Citric acid monohydrate is a natural preservative and food tartness enhancer. Citric acid monohydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid monohydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid monohydrate is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5949-29-1. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g; 50 g; 100 g. Product ID: HY-N1428A. | |
| Citric acid trisodium | Citric acid trisodium (Sodium citrate) is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sodium citrate; Trisodium citrate anhydrous. CAS No. 68-04-2. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B2201. | |
| Citrus red 2 | Citrus red 2 (CI Solvent red 80) is a synthetic dye with coloring power and antioxidant activity. Citrus red 2 can be used in food and cosmetics to provide a bright color to the product. Citrus red 2 is also used as a reference substance for testing and analysis in certain situations. Uses: Scientific research. Category: Signaling pathways. Alternative Names: C.I. Solvent red 80. CAS No. 6358-53-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-W775174. | |
| Ciwujianoside C3 | Ciwujianoside C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax henryi Harms. Ciwujianoside C3 has anti-inflammatory effect and can reinforces object recognition memory[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 114906-74-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N4134. | |
| Cixutumumab | Cixutumumab (IMC-A12) is a human anti-IGF-1R monoclonal antibody with high affinity that inhibits ligand-dependent receptor activation and downstream signaling. Cixutumumab also mediates the internalization and degradation of IGF-IR. Cixutumumab shows broad-spectrum anti-tumour activity and can be used in studies of cancers such as lung cancer, malignancies, leukaemia, non-small cell lung cancer and prostate cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMC-A12; NSC742460. CAS No. 947687-12-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99189. | |
| Cizutamig | Cizutamig (CND-106) is a bispecific T-cell engager targeting BCMA and CD3. Cizutamig exhibits immunostimulatory and anti-tumor activities. Cizutamig can be used in research related to relapsed or refractory multiple myeloma and systemic lupus erythematosus[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CND-106; EMB-06. CAS No. 2919209-65-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990980. | |
| CJ-13,610 | CJ-13,610, a nonredox-type 5-LO inhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of exogenous AA with an IC50 of about 70 nM[1]. PMNL: polymorphonuclear leukocytes; AA: arachidonic acid. Uses: Scientific research. Category: Signaling pathways. CAS No. 179420-17-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106200. | |
| CJ28 | CJ28 is a cortisol biosynthesis inhibitor that significantly inhibits basal and stimulated cortisol production in human adrenal carcinoma cell lines. CJ28 exhibits inhibitory effects by reducing steroidogenesis and de novo cholesterol biosynthesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3047118-54-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-157528. | |
| CK156 | CK156, a chemical probe, is a highly selective death-associated protein kinase (DAPK) inhibitor with IC50s of 182 nM,34 μM, and 39 μM in the DRAK1 NanoBRET assay for DRAK1, CK2a1, and CK2a2, respectively. CK156 can be used for the research of autoimmune and inflammatory diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2910938-59-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149006. | |
| CK1-IN-2 | CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor with an IC50 values of 123, 19.8, 26.8, 74.3 nM for CK1a, CK1d, CK1e, p38a, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1383376-92-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153866. | |
| CK2 inhibitor 2 | CK2 inhibitor 2 is a potent, selective and orally active inhibitor of CK2, with an IC50 of 0.66 nM. CK2 inhibitor 2 shows high selectivity for Clk2 (IC50=32.69 nM)/CK2. CK2 inhibitor 2 exhibits favorable antiproliferative and antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2641079-92-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132175. | |
| CK-636 | CK-636 is a cell permeable inhibitor of Arp2/3 complex, that could inhibit actin polymerization, with IC50 values of 4 μM, 24 μM and 32 μM for human, fission yeast and bovine, respectively. CK636 blocks cell migration. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CK-0944636. CAS No. 442632-72-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-15892. | |
| CK-666 | CK-666 is a cell-permeable actin-related protein Arp2/3 complex inhibitor (IC50=12 μM). CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 442633-00-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16926. | |
| CK-869 | CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor, with an IC50 of 7 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 388592-44-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16927. | |
| CK-963 | CK-963 is an activator for cardiac troponin (cTnC) with Ki of 11.5 μM. CK-963 exhibits activity in enhancing cardiac contractility in Sprague-Dawley rats[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2851991-63-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-162345. | |
| CKI-7 | CKI-7 is a potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC50 of 6 μM and a Ki of 8.5 μM. CKI-7 is a selective Cdc7 kinase inhibitor. CKI-7 also inhibits SGK, ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). CKI-7 has a much weaker effect on casein kinase II and other protein kinases[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1177141-67-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W011109. | |
| CKI-7 free base | CKI-7 free base is a potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC50 of 6 μM and a Ki of 8.5 μM. CKI-7 free base is a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK, ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). CKI-7 free base has a much weaker effect on casein kinase II and other protein kinases[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 120615-25-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133028. | |
| c-Kit-IN-5-1 | c-Kit-IN-5 is potent inhibitor of c-Kit, with IC50s of 22 nM and 16 nM in kinase assay and cell assay, respectively. c-Kit-IN-5 shows more than 200-fold selectivity for c-Kit over KDR, p38, Lck, and Src. c-Kit-IN-5 also exhibits desirable pharmacokinetic properties[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1003311-62-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-18302. | |
| CKK-E12 | CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based research. CKK-E12 is highly selective toward liver parenchymal cell in vivo. Uses: Scientific research. Category: Signaling pathways. CAS No. 1432494-65-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134781. | |
| CKS-17 | CKS-17 is a synthetic retroviral envelope peptide. CKS-17 has the highly conserved amino acid sequences occurring within the transmembrane envelope protein of many animal and human retroviruses. CKS-17 acts as an immunomodulatory epitope and exhibits suppressive properties for numerous immune functions[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 99273-04-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3051. | |
| CL075 | CL075 (3M002) is a selective TLR8 agonist with immunomodulating properties. CL075 triggers a MyD88-dependent signaling pathway to elicit production of inflammatory cytokines and type I interferons (IFNs) via activation of NF-κB and IRF7, respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3M002. CAS No. 256922-53-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117066. | |
| CL097 | CL097, a potent TLR7 and TLR8 agonist, induces pro-inflammatory cytokines in macrophages[1]. CL097 induces NADPH oxidase priming, resulting in an increase of the fMLF-stimulated ROS production[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1026249-18-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128799. | |
| CL097 hydrochloride | CL097, a potent TLR7 and TLR8 agonist, induces pro-inflammatory cytokines in macrophages[1]. CL097 induces NADPH oxidase priming, resulting in an increase of the fMLF-stimulated ROS production[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2990770-48-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-128799A. | |
| CL-197 | CL-197 is an orally active and long-acting purine anti-HIV nucleoside reverse transcriptase inhibitor (NRTI). CL-197 has potential effect on the research of viral, oncological and cerebrovascular diseases[1]. CL-197 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1030595-07-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148191. | |
| CL264 | CL264 is a TLR7-specific agonist for innate immune signals research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1510712-69-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135905. | |
| CL2A-SN-38 | CL2A-SN-38 is a agent-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody agent conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A-SN-38 uses hydrolyzable linker to deliver active agents within tumor cells and in the tumor microenvironment, resulting in bystander effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1279680-68-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128946. | |
| CL2-SN-38 | CL2-SN-38 is a cleavable linker-based agent-Linker conjugate, it can conjugate with the anti-Trop-2-humanized antibody hRS7. CL2-SN-38 can be used for the reasearch of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1036969-20-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126350. | |
| CL 316243 | CL316243 is a highly potent selective β3-adrenoceptor agonist with a EC50 of 3 nM, but is an extremely poor to β1/2- receptors[1].CL316243 is a effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate[2]. CL316243 has the potential for the treatment obesity, diabetes and urge urinary incontinence[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 138908-40-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116771A. | |
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