MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| CP-24879 hydrochloride | CP-24879 (hydrochloride) is a potent, selective and combined delta5D/delta6D inhibitor. CP-24879 (hydrochloride) can significantly reduce intracellular lipid accumulation and inflammatory injury in hepatocytes. CP-24879 (hydrochloride) exhibits superior antisteatotic and anti-inflammatory actions in fat-1 and ω-3-treated hepatocytes, and can be used for non-alcoholic steatohepatitis research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10141-51-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115319. |  |
| CP26 | CP26 is a small molecule inhibitor of protein dislocation from the ER lumen to the cytosol. CP26 targets the Hrd1 complex, inhibits ERAD, and induces ER stress[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 500285-30-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-49116. | |
| CP-312 | CP-312 is a potent Heme Oxygenase-1 (HO-1) inducer. CP-312 protects hiPSC-CM viability by targeting the antioxidant response network through induction of HMOX1 expression. CP-312 protects human iPSC-derived cardiomyocytes from oxidative stress[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 895470-67-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124815. | |
| CP-31398 dihydrochloride | CP-31398 dihydrochloride stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1217195-61-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18343A. | |
| CP-316819 | CP-316819 (GPi 819) is a blood-brain barrier permeable glycogen phosphorylase inhibitor. CP-316819 inhibits hepatic glycogenolysis, safely reduces blood glucose in type 2 diabetes, and rarely induces hypoglycemia. CP-316819 increases brain glycogen reserves, protects neurons, alleviates hypoglycemic brain injury, and inhibits excessive platelet activation, exerting both neuroprotective and vasculoprotective effects. CP-316819 can be used in research related to hypoglycemia, thrombosis, autoimmune inflammatory diseases, and type 2 diabetes[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GPi 819. CAS No. 186392-43-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108615. | |
| CP 339818 hydrochloride | CP 339818 hydrochloride is a non-peptide Kv1.3 channel (IC50 = 200 nM) and Kv1.4 channel blocker. CP 339818 hydrochloride inhibits HCN channel with IC50s of 18.9 μM and 43.4 μM against HCN1 and HCN4 (high Cl-). CP 339818 hydrochloride has significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels. CP 339818 hydrochloride selectively blocked Kv1.3, thereby inhibiting the activation process of human T cells. CP 339818 hydrochloride can be used to study the physiological functions of HCN and Kv channels[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 478341-55-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108574. | |
| CP-346086 | CP-346086 is a potent and orally active microsomal triglyceride transfer protein (MTP) inhibitor, with an IC50 of 2.0 nM for human and rodent MTP. CP-346086 can lower plasma cholesterol and triglycerides in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 186390-48-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113955. | |
| CP-409092 hydrochloride | CP-409092 hydrochloride is a partial agonist of GABAA receptor, with anti-anxiety activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 225240-86-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101639A. | |
| CP-466722 | CP-466722 is a rapidly reversible inhibitor of ATM, with an IC50 of 0.41 μM, and has no effects on PI3K or closely related PI3K-like protein kinase (PIKK) family members. Uses: Scientific research. Category: Signaling pathways. CAS No. 1080622-86-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-11002. | |
| CP-471474 | CP-471474 is an orally active and pan MMP inhibitor, with IC50 values of 1170 nM (MMP-1), 0.7 nM (MMP-2), 16 nM (MMP-3), 13 nM (MMP-9) and 0.9 nM (MMP-13), respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 210755-45-6. Pack Sizes: 1 mg. Product ID: HY-W011085. | |
| CP-506 mesylate | CP-506 (compound 26) mesylate is an anticancer compound and a substrate for nitroreductase and CYP oxidoreductases. CP-506 has anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2227304-19-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-149769A. | |
| CP-547632 | CP-547632 is an orally active, ATP-competitive and potent VEGFR-2 and FGF kinases inhibitor with IC50s of 11 nM and 9 nM, respectively. CP-547632 is selective for VEGFR2 and bFGF over EGFR, PDGFRβ, and related tyrosine kinases (TKs). CP-547632 has antitumor efficacy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 252003-65-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13302. | |
| CP5V | CP5V is a PROTAC connected by ligands for von Hippel-Lindau and CDK, which specifically degrades Cdc20 by linking Cdc20 to the VHL/VBC complex for ubiquitination followed by proteasomal degradation. CP5V induces mitotic inhibition and suppresses cancer cell proliferation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2509359-75-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-130257. | |
| CP-609754 | CP-609754 (LNK-754) is a potent and reversible farnesyltransferase inhibitor with potential anticancer activity.The IC50 for inhibiting farnesylation of recombinant human H-Ras is 0.57 ng/mL and recombinant K-Ras is 46 ng/mL[1]. CP-609754 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LNK-754; OSI-754. CAS No. 1190094-64-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16373. | |
| CP-640186 | CP-640186 is an orally active and cell-permeable Acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA. CP-640186 can also stimulate muscle fatty acid oxidation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 591778-68-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15259. | |
| CP-640186 hydrochloride | CP-640186 hydrochloride is an orally active and cell-permeable Acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA. CP-640186 hydrochloride can also stimulate muscle fatty acid oxidation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 591778-70-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15259A. | |
| CP-673451 | CP-673451 is a potent and selective inhibitor of PDGFR with IC50s of 10 and 1 nM for PDGFRα and PDGFRβ, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 343787-29-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12050. | |
| CP681301 | CP681301 is a potent CDK5 inhibitor. CP681301 shows antiproliferative activity. CP681301 decreases the expression of CD133, OLIG2, SOX2, KI67, pCDK5 protein level in GSCs (Glioma stem cells). CP681301 reduces self-renewal in mouse glioma xenografts. CP681301 shows anti-tumor activity in Drosophila[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 865317-32-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-150082. | |
| CP-775146 | CP-775146 is a selective PPARα agonist (Ki of 24.5 nM) that binds strongly to the PPARα ligand. CP-775146 has no observable affinity for PPARβ and PPARγ.CP-775146 shows hypolipidemic activity. CP-775146 efficiently alleviates obesity-induced liver damage, prevents lipid accumulation by activating the liver fatty acid β-oxidation pathway[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 702680-17-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108571. | |
| CP-809101 hydrochloride | CP-809101 hydrochloride is a potent and highly selective 5-HT2C receptor agonist, with pEC50s of 9.96, 7.19 and 6.81 M for human 5HT2C, 5HT2B and 5HT2A receptor. CP-809101 hydrochloride inhibits conditioned avoidance responding in rats and antagonizes both PCP (phencyclidine hydrochloride)- and d-amphetamine-induced hyperactivity. CP-809101 hydrochloride also reduces food and nicotine dependence in rats, can be used in studies of antipsychotic and nicotine dependence[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1215721-40-6. Pack Sizes: 10 mM * 1 mL in Water; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15543A. | |
| CP-91149 | CP-91149 is a GP (glycogen phosphorylase) inhibitor. CP-91149 promotes glycogen resynthesis, but not its overaccumulation. CP-91149 has the potential for Type II (insulin-dependent) diabetes study[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 186392-40-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13525. | |
| CP94253 hydrochloride | CP94253 hydrochloride is an orally active, brain-penetrant and selective 5-HT1B receptor agonist with an Ki of 2 nM. CP94253 hydrochloride induces antidepressant-like effects, waking enhancement, sleep inhibition, increased sleep latency, hyperlocomotion, and suppressed aggressive behavior. CP94253 hydrochloride can be used for the research of depression and heightened aggressive behavior[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 845861-39-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103151. | |
| CP-96,345 | CP-96,345 is a specific, highly potent, and orally active tachykinin and substance P receptor non-peptide inhibitor. CP-96,345 prevents the drop in blood pressure evoked by substance P and neurokinin A. CP-96,345 can be used for researching neurogenic inflammation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 132746-60-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108482. | |
| CPA inhibitor | CPA inhibitor (Compound 5) (Carboxypeptidase inhibitor) is an orally active competitive carboxypeptidase A (CPA) inhibitor with a Ki value of 0.32 μM. CPA inhibitor blocks the activity of carboxypeptidase A3 (CPA3). CPA activator activates the Wnt/Lrp6/β-catenin signaling pathway. CPA inhibitor reduces epithelial damage. CPA inhibitor is applicable to research related to inflammatory bowel disease, including ulcerative colitis and Crohn's disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Carboxypeptidase inhibitor. CAS No. 223532-02-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-70005. | |
| CPD-10 | CPD-10 is a potent CCND1 and CDK4 PROTAC degrader. CPD-10 exhibits anti-proliferative effects on tumor cells and can also induce apoptosis. CPD-10 can be used for the study of breast cancer and lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3055471-57-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-168660. | |
| CPD-1224 | CPD-1224 is an orally effective ALK inhibitor, a derivative of an ALK inhibitor that connects to the cereblon ligand. CPD-1224 targets the EML4-ALK oncogenic fusion protein and degrades both ALK and the mutant forms L1196M/G1202R. CPD-1224 can slow down tumor growth[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2891620-68-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153386. | |
| CPD-39 | CPD-39 is a potent and orally active CCND1 and CDK4 heterobifunctional PROTAC degrader. CPD-39 shows anti-proliferation. (Pink: ligand for target protein (HY-50767); black: linker (HY-20240); Blue: E3 ligase ligand (HY-168667))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3055472-38-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-168664. | |
| CPDA | CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 1415834-63-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18685. | |
| CPG-52364 | CPG-52364 (compound 2) is a TLR9 antagonist. CPG-52364 inhibits the HEK293-hTLR9 cell with an IC50 value of 4.6 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1093135-60-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-120538. | |
| C-Phycocyanin | C-phycocyanin (C-PC) is a protein pigment which is also widely used as an excellent nutrient supplement for human beings. Uses: Scientific research. Category: Signaling pathways. Alternative Names: C-PC. CAS No. 11016-15-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1025. | |
| CPI1 | CPI1 is a multidrug resistance protein 1 (MRP1) inhibitor with a Ki value of 100 nM. CPI1 binds to the same substrate-binding site as leukotriene C4, stabilizes MRP1 in an apo-like inward-facing conformation, blocks the conformational changes required for ATP hydrolysis and substrate transport, and inhibits the ATPase activity of human and bovine MRP1. CPI1 serves as a tool for investigating the substrate transport mechanism of MRP1. CPI1 is applicable to research related to cancer multidrug resistance[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3085809-95-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P10856. | |
| CPI-1612 | CPI-1612 is a highly potent, orally active EP300/CBP histone acetyltransferase (HAT) inhibitor with an IC50 of 8.1 nM for EP300 HAT. CPI-1612 has an anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2374971-81-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136285. | |
| CPI-203 | CPI-203 is a novel potent, selective and cell permeable inhibitor of BET bromodomain, with an IC50 value of appr 37 nM (BRD4 α-screen assay). Uses: Scientific research. Category: Signaling pathways. CAS No. 1446144-04-2. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15846. | |
| CPI-455 | CPI-455 is a specific, pan-KDM5 inhibitor with an IC50 of 10 nM for KDM5A. CPI-455 mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1628208-23-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100421. | |
| CPI-455 hydrochloride | CPI-455 hydrochloride is a specific, pan-KDM5 inhibitor with an IC50 of 10 nM for KDM5A. CPI-455 hydrochloride mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2095432-28-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-100421A. | |
| CPI-637 | CPI-637 is a selective and potent CBP/EP300 bromodomain inhibitor with IC50 values of 0.03 μM, 0.051 μM and 11.0 μM for CBP, EP300 and BRD4 BD-1, respectively, and an EC50 of 0.3 μM for CBP[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1884712-47-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100482. | |
| CPK20 | CPK20 is a potent and highly selective KCNT1 channel blocker, and CPK20 can be used in the study of epilepsy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2397708-22-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162549. | |
| CPL304110 | CPL304110 is a potent, orally active and selective inhibitor of fibroblast growth factor receptors FGFR (1-3), with IC50 values of 0.75 nM, 0.5 nM, and 3.05 nM for FGFR (1-3), respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1627826-19-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-131908. | |
| CPM | CPM is a maleimide derivative, acting as a blue fluorescent thiol-reactive dye (excitation/emission maxima of 387/463 nm)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 76877-33-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0069. | |
| CPN-219 | CPN-219, a next-generation hexapeptidic NMUR2 agonist, achieves a dose-dependent and selective activation of NMUR2 with an EC50 value of 2.2 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2240202-02-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3030. | |
| CPPG | CPPG ((RS)-CPPG) is a potent group II/III mGlu receptors antagonist. CPPG exhibits some selectivity (approximately 20 fold) for group III (IC50=2.2 nM) over group II (IC50=46.2 nM) mGlu receptors in the rat cerebral cortex. CPPG has weak effects at group I mGlu receptors[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (RS)-CPPG. CAS No. 183364-82-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-101333. | |
| CPS2 | CPS2 is a first-in-class, highly potent, selective and irreversible PROTAC CDK2 degrader (IC50= 24 nM). CPS2 can be used for the research of acute myeloid leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2756741-90-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141680. | |
| (±)-CPSI-1306 | (±)-CPSI-1306 is an orally available antagonist of macrophage migration inhibitory factor (MIF). Uses: Scientific research. Category: Signaling pathways. CAS No. 1309793-47-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110095. | |
| CPT-157633 | CPT-157633, a difluoro-phosphonomethyl phenylalanine derivative, and is a PTP1B inhibitor. CPT-157633 prevents binge drinking-induced glucose intolerance[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 888213-72-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111469. | |
| CPTH2 | CPTH2 is a potent histone acetyltransferase (HAT) inhibitor. CPTH2 selectively inhibits the acetylation of histone H3 by Gcn5. CPTH2 induces apoptosis and decreases the invasiveness of a clear cell renal carcinoma (ccRCC) cell line through the inhibition of acetyltransferase p300 (KAT3B)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 357649-93-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W013274. | |
| CPUY192018 | CPUY192018 is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, with an IC50 of 0.63 μM. CPUY192018 exhibits anti-inflammatory and antioxidant activities. CPUY192018 can activate the Nrf2-dependent antioxidant pathway and inhibit the NF-κB-related inflammatory response. CPUY192018 can be used in the research of inflammation-related diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1567836-15-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120371. | |
| CPYPP | CPYPP is a DOCK2-Rac1 interaction inhibitor. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner with an IC50 of 22.8 μM. CPYPP also inhibits DOCK180 and DOCK5 and less inhibits DOCK9[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 310460-39-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110100. | |
| CQ211 | CQ211 is a potent and selective RIOK2 inhibitor with a Kd of 6.1 nM. CQ211 exhibits potent proliferation inhibition activity against multiple cancer cell lines[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2648986-65-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-147655. | |
| CQ627 | CQ627 is a molecular glue targeting the degradation of RIOK2. It effectively induces the degradation of RIOK2 in the MOLT4 leukemia cell line via the ubiquitin-proteasome system (UPS) by recruiting the E3 ubiquitin ligase RNF126, with a DC50 value of 410 nM. CQ627 dose-dependently induces apoptosis in MOLT4 leukemia cells, blocks their cell cycle in the G2/M phase, and exhibits antiproliferative activities in various cancer cell lines. CQ627 also demonstrates in vivo anticancer activity in a MOLT4 xenograft mouse model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3093767-34-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-170574. | |
| CQ-Lyso | CQ-Lyso is a lysosome-targeting chromenoquinoline. CQ-Lyso is a fluorescent probe for measuring the pH of lysosomes in living cells using only single wavelength excitation. CQ-Lyso can visualize the dynamic pH changes in lysosomes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2089438-23-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D2119. | |
| CR-1-31-B | CR-1-31-B is a synthetic rocaglate and a potent eIF4A inhibitor. CR-1-31-B exhibits powerful inhibitory effects over eIF4A by perturbing the interaction between eIF4A and RNA, sequentially impeding initiation during protein synthesis. CR-1-31-B perturbs association of Plasmodium falciparum eIF4A (PfeIF4A) with RNA. CR-1-31-B induces apoptosis of neuroblastoma and gallbladder cancer cells[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1352914-52-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-136453. | |
| CR-8020 | CR-8020 is a human IgG1 antibody that targets influenza A virus H3N2. CR-8020 binds to hemagglutinin (HA) of H3N2 strains with IC50s of 3.36 nM and 0.06 nM for A/Brisbane/10/2007 and A/Wyoming/3/2003, respectively. The isotype control for CR-8020 can refer to Human IgG1 kappa, Isotype Control (HY-P99001)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1422526-93-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991054. | |
| CRAMP (mouse) | CRAMP (mouse) is an antibacterial peptide and a functional homolog of LL-37. CRAMP (mouse) exhibits potent antibacterial activity against Gram-negative bacteria. The complex formed by CRAMP (mouse) and CpG can activate macrophages to secrete TNF-α. CRAMP (mouse) plays a key role in wound healing, immune regulation and maintenance of intestinal homeostasis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 376364-36-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P4855. | |
| CRANAD-2 | CRANAD-2 is a specific near-infrared (NIR) fluorescent probe for detecting Aβ plaques (unbound to Aβ: Ex=640 nm; Em=805 nm; after binding: Em=715 nm). CRANAD-2 penetrates the blood-brain barrier and has high affinity for Aβ aggregates, with a Kd value of 38 nM. CRANAD-2 is applicable to research related to Alzheimer's disease and neurodegenerative diseases[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1193447-34-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-103242. | |
| CRANAD-28 | CRANAD-28 is a robust fluorescent compound for visualization of amyloid beta plaques[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1623747-97-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-123495. | |
| CRBN-6-5-5-VHL | CRBN-6-5-5-VHL is a potent and selective von Hippel-Lindau-based cereblon (CRBN) degrader with a DC50 value of 1.5 nM. CRBN-6-5-5-VHL has almost no effect on the degradation of the neo-substrates IKZF1 and IKZF3. (Pink: VHL ligand (HY-125845); Blue: E3 Ligase ligand (HY-10984); Black: linker (HY-403544))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2362575-45-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136262. | |
| CRBN ligand-109 | CRBN ligand-109 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC. Uses: Scientific research. Category: Signaling pathways. CAS No. 2758533-77-4. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W440247. | |
| CRBN ligand-394 | CRBN ligand-394 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-394 can be linked to a target protein ligand via a linker to form a PROTAC. Uses: Scientific research. Category: Signaling pathways. CAS No. 2641512-77-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W886316. | |
| CRBN ligand-397 | CRBN ligand-397 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-397 can be linked to a target protein ligand via a linker to form a PROTAC. Uses: Scientific research. Category: Signaling pathways. CAS No. 2736511-32-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W998293. | |
| CRBN ligand-47 | CRBN ligand-47 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC. Uses: Scientific research. Category: Signaling pathways. CAS No. 3059455-81-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-170108. | |
| CRBN ligand-547 | CRBN ligand-547 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-547 can be linked to a target protein ligand via a linker to form a PROTAC. Uses: Scientific research. Category: Signaling pathways. CAS No. 2446913-88-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W593975. | |
| CRBN ligand-774 | CRBN ligand-774 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-774 can be linked to a target protein ligand via a linker to form a PROTAC. Uses: Scientific research. Category: Signaling pathways. CAS No. 2888604-15-5. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W883939. | |
| CRBN ligand-880 | CRBN ligand-880 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-880 can be linked to a target protein ligand via a linker to form a PROTAC. Uses: Scientific research. Category: Signaling pathways. CAS No. 1267337-47-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-24538. | |
| CRCD2 | CRCD2 is a small molecule NT5C2 nucleotidase inhibitor with enhanced 6-mercaptopurine cytotoxic activity. CRCD2 can effectively reverse 6-mercaptopurine resistance caused by mutations in the NT5C2 gene or non-genetic activation mechanisms. CRCD2 combined with 6-mercaptopurine can enhance its cytotoxic activity in NT5C2 wild-type leukemia, showing its potential in the treatment of acute lymphoblastic leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 941185-83-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-167710. | |
| C-Reactive Protein (CRP) (174-185) | C-Reactive Protein (CRP) is an anti-pneumococcal plasma protein that can serve as an inflammatory marker. C-Reactive protein can protect mice from pneumococcal infection by activating complement. C-Reactive protein can inhibit the activation of caspase-3/9 through the CD64/AKT/mTOR pathway, thereby promoting chemotherapy resistance in mice with tongue squamous cell carcinoma[1][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 147516-85-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1823. | |
| Creatinase, Actinobacteria | Creatinase, Actinobacteria (Creatine amidohydrolase) is a hydrolase that catalyzes the hydrolysis of creatine into sarcosine and urea, and plays an important role in the enzymatic determination of creatinine concentration[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Creatine amidohydrolase. CAS No. 37340-58-2. Pack Sizes: 1 KU; 5 KU; 10 KU. Product ID: HY-P2893. | |
| Creatinase, microorganism | Creatine amidinohydrolase, microorganism is a hydrolytic enzyme that catalyzes the hydrolysis of creatine into creatinine and urea, playing a crucial role in the measurement of creatinine concentration. Creatine amidinohydrolase, microorganism can be used in the development of biosensors for measuring serum creatinine levels[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Creatine amidinohydrolase, microorganism. CAS No. 37340-58-2. Pack Sizes: 1 KU; 5 KU. Product ID: HY-P2893B. | |
| Creatine | Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain. Uses: Scientific research. Category: Signaling pathways. CAS No. 57-00-1. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 5 g. Product ID: HY-W010388. | |
| Creatine-d3 | Creatine-d3 is the deuterium labeled Creatine (HY-W010388)[1]. Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 143827-19-4. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg. Product ID: HY-W010388S1. | |
| Creatine-d3 hydrate | Creatine-d3 (hydrate) is a deuterium labeled Creatine hydrate. Creatine hydrate is pivotal in energy metabolism of muscle and brain cells, both in physiological and in pathological conditions[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 284664-86-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W010388AS. | |
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