BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| AR03 | AR03 is a specific inhibitor of apurinic/apyrimidinic (AP) endonuclease 1 (APE1). Synonyms: BMH-23; BMH 23; BMH23; AR03; AR 03; AR-03; 2,4,9-trimethylbenzo[b][1,8]naphthyridin-5-amine. Grade: 99%. CAS No. 510721-85-4. Molecular formula: C15H15N3. Mole weight: 237.3. |  |
| AR-?08 | AR-08 is an agonist of α2-adrenergic receptor undergone in phase II clinical trials by Arbor Pharmaceuticals for the treatment of attention deficit and hyperactivity disorder (ADHD). Synonyms: AR-08; AR ?08; AR?08; 6-(4,5-dihydro-1H-imidazol-2-ylamino)-7-methyl-3H-benzimidazole-4-carbonitrile; 1H-Benzimidazole-7-carbonitrile, 5-[(4,5-dihydro-1H-imidazol-2-yl)amino]-4-methyl-; 6-[(4,5-Dihydro-1H-imidazol-2-yl)amino-]-7-methyl-1H-benzimidazole-4-carbonitrile. CAS No. 226081-74-9. Molecular formula: C12H12N6. Mole weight: 240.26. | |
| AR12456 | AR12456 is a trapidil derivative. It could protect against serum hyperlipidemia in guinea pigs. It has a strong antilipidemic action in guinea pigs fed a cholesterol-rich diet. Uses: Ar12456 could protect against serum hyperlipidemia and has a strong antilipidemic action. Synonyms: AR 12456; AR-12456; AR12456; Ethanol,2-[[5-(diethylamino)[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]hexylamino]-; AR-12456; 2-[[5-(Diethylamino)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]-hexylamino]ethanol; 2-[(4-Diethylamino-1,5,7,9-tetrazabicyclo[4.3.0]nona-2,4,6,8-tetraen-2 -yl)-hexyl-amino]ethanol. Grade: >98 %. CAS No. 100557-06-0. Molecular formula: C17H30N6O. Mole weight: 334.47. | |
| AR12463 | AR12456 is a trapidil derivative. It protects against serum hyperlipidemia in guinea pigs. It has a strong antilipidemic action in guinea pigs fed a cholesterol-rich diet. Uses: Ar12456 could protect against serum hyperlipidemia and has a strong antilipidemic action. Synonyms: AR 12463; AR-12463; AR12463; Ethanol,2-[pentyl[5-(1-piperidinyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino]-; 2-[Pentyl-(5-piperidin-1-yl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)amino]ethanol; 2-[N-Pentyl-N-[[5-piperidino[1,2,4]triazolo[1,5-a]pyrimidin]-7-yl]amino]ethanol. Grade: >98 %. CAS No. 100557-04-8. Molecular formula: C17H28N6O. Mole weight: 332.45. | |
| AR-12 Hydrochloride | OSU 03012, a Phenanthren derivative, has been found to be a PDPK1 inhibitor that could probably be an effctive antitumor agent. It is still under Phase I trail for solid-tumour. IC50: 5 μM. Synonyms: OSU-03012; AR-12; AR 12; AR12; OSU 03012; OSU03012; PDK1 inhibitor AR-12; 2-amino-N-[4-[5-phenanthren-2-yl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]acetamide. Grade: 98%. CAS No. 1471979-81-3. Molecular formula: C26H19F3N4O. Mole weight: 460.46. | |
| AR17048 | AR17048 is used as a potential antirheumatic drug. Uses: Ar17048 is used as a potential antirheumatic drug. Synonyms: AR-17048; AR 17048; 2-Phenyl-4-(beta-dimethylaminoethyl)-6-methyl-2,3-dihydro-1,4-benzoxazin-3-one. Grade: 98%. CAS No. 65792-35-0. Molecular formula: C19H22N2O2. Mole weight: 310.39. | |
| AR 231453 | AR231453 is a potent and selective small molecule agonist of GPR119 that enhances glucose-dependent insulin secretion and glucagon-like peptide 1 (GLP-1) release. It is Antidiabetic agent. Synonyms: AR231453; AR-231453; AR 231453; AR-231,453; AR231,453; AR231,453. Grade: >98%. CAS No. 733750-99-7. Molecular formula: C21H24FN7O5S. Mole weight: 505.52. | |
| AR 244555 | AR 244555 is an inverse agonist of Mas G-protein signaling (IC50 values 186 and 348 nM in human and rat inositol phosphatase (IP) Gq coupling assays respectively). AR 244555 inhibited inositol 1,4,5-trisphosphate accumulation in AdMas-infected cells and attenuated the sarcomeric organization and cell enlargement observed in Mas overexpressing myocytes. AR 244555 caused an increase in coronary flow in rat hearts without causing arrhythmias, and provides protection from ischemia-reperfusion injury if administered either before ischemia or immediately before reperfusion. Synonyms: AR244555; AR 244555; AR-244555; (1'-but-3-enyl-5-chlorospiro[2H-indole-3,4'-piperidine]-1-yl)-(2,6-difluorophenyl)methanone. Grade: 99%. CAS No. 858350-62-6. Molecular formula: C23H23ClF2N2O. Mole weight: 416.89. | |
| AR-42 | AR-42 is an orally available, broad-spectrum deactylation inhibitor of both histone and non-histone proteins which play an important role in the regulation of gene expression, cell growth and survival. In preclinical studies, AR-42 has demonstrated greater potency and activity in solid and liquid tumors when compared to vorinostat and other deacetylase inhibitors. AR-42 is currently being studied in an investigator-initiated Phase I/IIa clinical study in adult patients with relapsed or refractory multiple myeloma, chronic lymphocytic leukemia or lymphoma. Synonyms: HDAC-42; HDAC42; HDAC 42; OSU-HDAC-42; OSU HDAC 42; AR-42; AR42; AR 42. Grade: 98%. CAS No. 935881-37-1. Molecular formula: C18H20N2O3. Mole weight: 312.37. | |
| AR 420626 | AR 420626 ,a FFA3 agonist, has been found to be expressed in adipose tissue, the gastrointestinal tract, and the peripheral nervous system, and it is involved in SCFA-dependent energy regulation. Synonyms: AR-420626; AR 420626; AR420626. N-(2,5-Dichlorophenyl)-4-(furan-2-yl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxamide. Grade: ≥98% by HPLC. CAS No. 1798310-55-0. Molecular formula: C21H18Cl2N2O3. Mole weight: 417.29. | |
| AR-7 | AR-7, also known as Atypical retinoid 7, was developed as a highly potent and selective enhancer of the chaperone-mediated autophagy (CMA) through antagonizing RARα. AR-7 was suggested to be used at 5-20 μM final concentration in vitro and in cellular assays. Synonyms: 7-Chloro-3-(p-tolyl)-2H-benzo[b][1,4]oxazine; AR 7; AR7; Atypical retinoid 7. CAS No. 80306-38-3. Molecular formula: C15H12ClNO. Mole weight: 257.71. | |
| AR709 | AR709 is a novel diaminopyrimidine antibiotic. It is currently in development for treatment of community-acquired upper and lower respiratory tract infections. It showed excellent activity against both drug-susceptible and multidrug-resistant pneumococci. Uses: Ar709 is currently in development for treatment of community-acquired upper and lower respiratory tract infections. Synonyms: AR-709; AR 709; 1H-Indole-2-carboxamide, 5-chloro-3-((4-((2,4-diamino-5-pyrimidinyl)methyl)-6,7-dimethoxy-2-benzofuranyl)methyl)-N,N-dimethyl-. Grade: 98%. CAS No. 663214-64-0. Molecular formula: C27H27ClN6O4. Mole weight: 535.00. | |
| AR-A014418 | AR-A014418 is an ATP-competitive inhibitor of glycogen synthase kinase 3β (GSK-3β), a serine/threonine protein kinase involved in multiple diseases including Alzheimer's disease and type 2 diabetes. Synonyms: SN 4521; SN4521; SN-4521; AR-A 014418; AR-A014418; AR-A-014418; AR-AO-14418; GSK-3beta Inhibitor VIII; 1-[(4-methoxyphenyl)methyl]-3-(5-nitro-1,3-thiazol-2-yl)urea. Grade: ≥ 98%. CAS No. 487021-52-3. Molecular formula: C12H12N4O4S. Mole weight: 308.312. | |
| ara-Adenosine-5'-monophosphate (ara-AMP) | ara-Adenosine-5'-monophosphate (ara-AMP) is an adenosine monophosphate analog with antiviral and possibly antineoplastic properties. It inhibits DNA polymerase and also acts as a chain terminator in DNA replication. Synonyms: Vidarabine monophosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 29984-33-6. Molecular formula: C10H14N5O7P (free acid). Mole weight: 347.22 (free acid). | |
| ara-Adenosine-5'-triphosphate | ara-Adenosine-5'-triphosphate (ara-ATP) is an adenosine triphosphate analog with an antiviral property that inhibits cleavage and polyadenylation reactions by interacting with the ATP-binding site on poly(A) polymerase. Synonyms: Araadenosine-5'-Triphosphate; Vidarabine triphosphate; Ara-ATP. Grade: ≥ 95% by HPLC. CAS No. 3714-60-1. Molecular formula: C10H16N5O13P3 (free acid). Mole weight: 507.18 (free acid). | |
| Arabinan | Arabinan is an intriguing biopolymer procured from plants including gum arabic and diverse fruits. It has profound immunomodulatory and anticancer attributes. CAS No. 11078-27-6. | |
| Arabinaric acid | Arabinaric acid is the illustrious biochemical compound, used for studying an assortment of diseases, encompassing the cancer. Synonyms: Glutaric acid, arabino-trihydroxy-; Lyxaric acid. CAS No. 6703-5-5. Molecular formula: C5H8O7. Mole weight: 180.11. | |
| Arabinofuranosyl-2,6-diamino-purine | Arabinofuranosyl-2,6-diamino-purine, a potent antiviral agent, is indicated for the prevention and treatment of viral infections such as herpes simplex, varicella-zoster virus, and hepatitis B. This drug acts by impeding synthesis of viral DNA, effectively suppressing replication of the virus. Recommended for intravenous administration, Arabinofuranosyl-2,6-diamino-purine is particularly useful in immunocompromised patients, especially those suffering from HIV/AIDS, who are at greater risk of succumbing to viral infections. Synonyms: 2,6-diaminopurine arabinoside; 9-(β-D-Arabinofuranosyl)-2,6-diaminopurine. Grade: ≥ 99%. Molecular formula: C10H14N6O4. Mole weight: 282.25. | |
| Arabinofuranosyl-6-benzylamino-purine | Arabinofuranosyl-6-benzylamino-purine is a highly antiviral compound, finding extensive applications in a wide range of ailments including leukemia and solid tumors. Thus, it standing as an invaluable compound for scientific investigations and the development of pharmaceutical interventions within the dynamic realm of compound. Synonyms: 6-Benzylaminopurine arabinoside; 9-(β-D-Arabinofuranosyl)-6-benzylaminopurine. Grade: ≥ 99%. Molecular formula: C17H19N5O4. Mole weight: 357.36. | |
| Arabinofuranosylcytosine-5'-triphosphate (triethylammonium salt form) | The triethylammonium salt form of Ara-CTP. Ara-CTP is a nucleotide that can be used as an antimetabolic agent to inhibit the synthesis of DNA. Synonyms: Ara-CTP (triethylammonium salt form); Cytosine arabinoside triphosphate triethylammonium; Arabinosylcytosine triphosphate triethylammonium; Arabinofuranosylcytosine triphosphate triethylammonium; Cytosine arabinoside 5'-triphosphate triethylammonium; Arabinosylcytosine 5'-triphosphate triethylammonium. Grade: ≥ 90% by HPLC, Concentration ~ 12 mM. Molecular formula: C9H16N3O14P3.C6H15N. Mole weight: 483.159 (free acid). | |
| Arabinofuranosyl-guanine (ara-G) | Arabinofuranosyl-guanine (ara-G) is an inhibitor of DNA synthesis used as an antimetabolic and antineoplastic agent. Synonyms: Arabinosylguanine; 2-Amino-9-β-D-arabinofuranosyl-1,9-dihydro-6H-purin-6-one; 2-Amino-6-hydroxy-9-(β-D-arabinofuranosyl)purine; 9-β-D-Arabinofuranosylguanine; Araguanosine; Guanine arabinoside; NSC 76352; ara-Guanosine; A 4233; Arabinoguanosine. Grade: ≥98% by HPLC. CAS No. 38819-10-2. Molecular formula: C10H13N5O5. Mole weight: 283.24. | |
| Arabinofuranosyl-hypoxanthine (ara-HX) | Arabinofuranosyl-hypoxanthine is a prodrug of Vidarabine for improving the oral bioavailability, which is an antiviral drug. It is an antimetabolic nucleoside that inhibits Streptococcus pyogenes and other bacteria, as well as zirconium oxide, pulmonary vasodilation, squamous cell carcinoma, and rate constant. Uses: Antiviral agents. Synonyms: Arabinofuranosyl-hypoxanthine; Arabino inosine; 9-β-D-Arabinofuranosyl-1,9-dihydro-6H-purin-6-one; Hypoxanthine, 9-β-D-arabinofuranosyl-; 9-β-D-Arabinofuranosylhypoxanthine; Ara-H; Arabinosylhypoxanthine; Arainosine; Hypoxanthine arabinoside; NSC 405122; 9-(β-D-Arabinofuranosyl)-hypoxanthine. Grade: ≥98%. CAS No. 7013-16-3. Molecular formula: C10H12N4O5. Mole weight: 268.22. | |
| Arabinofuranosyl-isoguanine | Arabinofuranosyl-isoguanine is a nucleoside analog used as an antiviral drug to treat herpes simplex virus type 1 and 2 infections. It works by inhibiting viral DNA synthesis, thus preventing the virus from replicating and spreading. Synonyms: 9-(β-D-Arabinofuranosyl)-isoguanine. Grade: ≥ 98%. Molecular formula: C10H13N5O5. Mole weight: 283.24. | |
| Arabinoisocytidine | Arabinoisocytidine: A pioneering compound widely utilized in the biomedical sector due to its remarkable potential in combating diverse viral infections and cancers. With its role as a nucleoside analog, Arabinoisocytidine showcases commendable antiviral and antitumor properties by obstructing viral DNA replication and instigating apoptosis within malignant cells. Synonyms: 2-Amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one; 2'beta-Hydroxy-2'-deoxy-2-amino-2-deoxo-2,3-didehydrouridine; NSC 529488; 2-Amino-1-(β-D-arabinofuranosyl)-4(1H)-pyrimidinone. Grade: ≥95%. CAS No. 10212-30-3. Molecular formula: C9H13N3O5. Mole weight: 243.22. | |
| Arabinosyluridine-5'-triphosphate (triethylammonium salt form) | An impurity of UTP. UTP is a pyrimidine nucleoside triphosphate as a substrate in the biosynthesis of RNA. Synonyms: Ara-UTP (triethylammonium salt form); Arabinofuranosyluridine triphosphate triethylammonium; 2'ara-UTP triethylammonium. Grade: 95%. Molecular formula: C9H15N2O15P3.C6H15N. Mole weight: 484.144 (free acid). | |
| Arabinoxylan | Arabinoxylan is a form of the hemicellulose xylan found in both the primary and secondary cell walls of plants. Arabinoxylan is a multifaceted and significant natural polysaccharide that shows great potential in the biomedical field. Its scientifically proven anti-inflammatory abilities, combined with its unmatched antioxidant properties, make it a valuable asset in alleviating countless conditions. Synonyms: Opti'flor; P-WAXYM; Xyloarabinan. CAS No. 9040-27-1. | |
| ara-cAMP | ara-cAMP is an analogue of cAMP, the second messenger. It is commonly used in receptor mapping studies and negative controls. Synonyms: Arabinoadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. CAS No. 32465-18-2. Molecular formula: C10H11N5O6P·Na. Mole weight: 351.2. | |
| Arachidonoyl-2'-fluoroethylamide | Arachidonoyl-2'-fluoroethylamide (2-fluoro AEA) is an analog of anandamide in which the alcohol of the ethanolamide group has been removed and replaced with a fluorine atom. Arachidonoyl 2'-fluoroethylamide is a CB1 receptor agonist with Ki of 26.7 nM for CB1 and Ki of 908 nM for CB2. The in vivo activity of 2-fluoro AEA is enhanced much less than the binding affinity, because the analog remains a good substrate for FAAH. Synonyms: 2'-fluoro AEA; 2'-fluoro Anandamide. Grade: ≥98%. CAS No. 166100-37-4. Molecular formula: C22H36FNO. Mole weight: 349.5. | |
| Arachidonoyl amide | Arachidonamide (AEA) is a weak cannabinoid CB1 and CB2 agonist. Arachidonamide was hydrolyzed by FAAH more effectively than AEA but exhibited significantly weaker binding to the human CB1 receptor with a Ki of 9.6 μM. AEA also inhibits rat glial gap junction cell-cell communication by 90% at a concentration of 20 μM. Arachidonamide are found to be the best substrates for anandamide amidohydrolase (AAH) with relative rates of hydrolysis about twice that of anandamide. Synonyms: Arachidonamide; Arachidonic acid amide; 5Z,8Z,11Z,14Z-eicosatetraenamide. Grade: ≥98%. CAS No. 85146-53-8. Molecular formula: C20H33NO. Mole weight: 303.5. | |
| Arachidonoyl cyclopropylamide | Arachidonoyl cyclopropylamide (ACPA) is a potent and selective cannabinoid (CB) receptor 1 agonist with Ki values of 2.2 nM for CB1 receptors and 715 nM for CB2 receptors. ACPA inhibits forskolin-induced cAMP accumulation, increases binding of GTPγS to cerebellar membranes, inhibits electrically-evoked contractions of mouse vas deferens and production of hypothermia in mice. Synonyms: ACPA. Grade: ≥98%. CAS No. 229021-64-1. Molecular formula: C23H37NO. Mole weight: 343.6. | |
| Arachidonoyl-N-methyl amide | Anandamide (N-arachidonylethanolamine, AEA) is a brain lipid that binds to cannabinoid receptors with high affinity and mimics the psychoactive effects of plant-derived cannabiniod drugs, which is a fatty acid neurotransmitter derived from the non-oxidative metabolism of eicosatetraenoic acid (arachidonic acid), an essential omega-6 fatty acid. Anandamide inhibits the specific binding of [3H]-HU-243 to synaptosomal membranes with a Ki value of 52 nM. Arachidonoyl-N-methyl amide is an analog of anandamide that binds to the human central cannabinoid (CB1) receptor with a Ki of 60 nM. It inhibits rat glial gap junction cell-cell communication 100% at a concentration of 50 μM. Synonyms: (5Z,8Z,11Z,14Z)-N-methyl-5,8,11,14-Eicosatetraenamide; N-Methylarachidonamide; (all-Z)-N-methyl-5,8,11,14-Eicosatetraenamide. Grade: ≥98%. CAS No. 156910-29-1. Molecular formula: C21H35NO. Mole weight: 317.5. | |
| Arachidonoyl serinol | Arachidonoyl Serinol is an amide bond-containing analogue of 2-arachidonoylglycerol, which exhibited weak CB1 receptor agonistic activity. 2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain. It is a product of increased inositol phospholipid metabolism. Replacement of the sn-2 oxygen in the glycerol moiety of 2-AG with a nitrogen atom gives arachidonoyl serinol. Arachidonoyl serinol is much more stable than 2-AG. Synonyms: N-arachidonoyl dihydroxypropylamine; 183718-70-9; AA dihydroxypropylamine; (5Z,8Z,11Z,14Z)-N-(1,3-dihydroxypropan-2-yl)icosa-5,8,11,14-tetraenamide; CHEMBL141463; Arachidonoyl Serinol; N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-(1,3-dihydroxy-propyl-2-amine); 5,8,11,14-Eicosatetraenamide,N-[2-hydroxy-1-(hydroxymethyl)ethyl]-, (5Z,8Z,11Z,14Z)-; N-[(2-Hydroxy-1-hydroxymethyl)ethyl]-5Z,8Z,11Z,14Z-eicosatetraenamide; Arachidonoylserinol; CHEBI:183197; QHELXIATGZYOIB-DOFZRALJSA-N; HMS3649C07; BDBM50054465; LMFA08020072; SR-01000946557; SR-01000946557-1; (5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid (2-hydroxy-1-hydroxymethyl-ethyl)-amide. Grade: ≥98%. CAS No. 183718-70-9. Molecular formula: C23H39NO3. Mole weight: 377.6. | |
| Arachidonyl serotonin | Arachidonyl serotonin is a dual target agent of transient receptor potential vanilloid-type I (TRPV1) antagonist and fatty acid amide hydrolase (FAAH) inhibitor, which is responsible for inactivation of anandamide and other endogenous cannabinoids. Its IC50 values are 37-40 nM and 5.6 μM for TRPV1 and FAAH respectively. It inhibits the FAAH activity isolated from mouse neuroblastoma cells with an IC50 value of 12 μM. It is a very tight binding, competitive inhibitor of FAAH. It does not inhibit cPLA2 and is essentially devoid of cannabimimetic activity. It was shown to be present in the ileum and jejunum of the gastrointestinal tract and modulate glucagon-like peptide-1 (GLP-1) secretion. It displays strong analgesic activity against both acute and chronic peripheral pain in rodents. Synonyms: AA-5HT; AA5HT; AA 5HT; N-arachidonoyl-serotonin; Arachidonoyl serotonin; N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-5Z,8Z,11Z,14Z-eicosatetraenamide; AA-5HT; AA5HT; N-arachidonoyl-serotonin; N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-5,8,11,14-eicosatetraenamide; (5Z,8Z,11Z,14Z)-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)icosa-5,8,11,14-tetraenamide. CAS No. 187947-37-1. Molecular formula: C30H42N2O2. Mole weight: 462.67. | |
| Ara-CTP | ara-Cytidine-5'-triphosphate (ara-CTP) is an inhibitor of DNA synthesis, DNA ligases and polymerases that is used for the treatment of acute myeloid leukemia. Uses: Nucleic acid synthesis inhibitors. Synonyms: 1-β-D-arabinofuranosylcytosine TP; Aracytidine-5'-Triphosphate; ara-Cytidine-5'-triphosphate; Arabinofuranosylcytosine triphosphate; 4-Amino-1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-arabinofuranosyl]-2(1H)-pyrimidinone; 1-β-D-Arabinofuranosylcytosine 5'-triphosphate; 1-β-D-Arabinosylcytosine triphosphate; 1-β-Arabinofuranosylcytosine 5'-triphosphate; Ara-C triphosphate; Arabinosylcytosine 5'-triphosphate; AraCTP; Cytosine arabinoside 5'-triphosphate; Cytosine β-D-arabinofuranoside-5'-triphosphate. Grade: ≥90% by AX-HPLC. CAS No. 13191-15-6. Molecular formula: C9H16N3O14P3. Mole weight: 483.16. | |
| ara-Cytidine-5'-diphosphate (ara-CDP) | Ara-Cytidine-5'-diphosphate (ara-CDP), an innovative nucleotide analog, plays a crucial role in the realm of anti-cancer therapy by thwarting DNA synthesis and triggering apoptosis in cancer cells. Known for its efficacy in treating acute myeloid leukemia and non-Hodgkin lymphoma, this compound is available in several formats and can be delivered through both oral and injection routes. Its versatile therapeutic potential has revolutionized cancer treatment paradigms by novelly combining precise cellular targeting with extensive delivery options. Synonyms: Cytarabine diphosphate; Cytidine-arabinofuranoside-5'-diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C9H15N3O11P2 (free acid). Mole weight: 403.17 (free acid). | |
| Ara-F-NAD+ | Ara-F-NAD+ is an arabino analogue of NAD+. It is a potent, slow-binding CD38 NADase inhibitor, with a Ki of 169 nM. Synonyms: nicotinamide 2'-deoxy-2'-fluororibofuranosyl adenine dinucleotide. CAS No. 133575-27-6. Molecular formula: C21H26FN7O13P2. Mole weight: 665.42. | |
| Ara-GTP | Ara-GTP serves as an antimetabolite for targeted cancer treatment. Its mechanism of action involves the interruption of DNA synthesis as well as the initiation of cell death in fast-replicating cancerous cells. With its specificity towards leukemia and lymphoma, it successfully hinders the generation of new malignant cells by inhibiting crucial DNA precursors. Synonyms: Araguanosine-5'-Triphosphate. Grade: ≥95% by AX-HPLC. Molecular formula: C10H16N5O14P3. Mole weight: 523.1. | |
| Araguspongin B | Araguspongin B is a compound isolated from Pacific basin sponges. It shows notable vasodilatory properties. Araguspongin B antagonizes the calcium-releasing action of inositol 1,4,5-trisphosphate at the receptor level with an IC50 value of 0.6 μM in cerebral microsomes. It is nearly as potent as xestospongin C as an antagonist of the IP3 receptor. Grade: ≥90%. CAS No. 123000-02-2. Molecular formula: C28H50N2O2. Mole weight: 446.7. | |
| Aranciamycin A | Aranciamycin A is an anthracyclic antibiotic originally isolated from Streptomyces. It is active against M. bovis and B. subtilis (MICs = 30 and 7.5 μM, respectively) but not S. aureus, E. coli, P. aeruginosa, or C. albicans (MICs = >30 μM for all). Synonyms: (8R,10S)-10-[(6-deoxy-2-O-methyl-alpha-L-mannopyranosyl)oxy]-7,8,9,10-tetrahydro-1,8,11-trihydroxy-8-methyl-5,12-naphthacenedione. Grade: >95%. CAS No. 960622-70-2. Molecular formula: C26H28O10. Mole weight: 500.49. | |
| Aranidipine | Aranidipine is a calcium channel blocker with long-lasting antihypertensive effects. By blocking calcium channels, it reduces peripheral vascular resistance, which is a significant determinant of arterial blood pressure. Synonyms: 2,6-Dimethyl-4-(2-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylic acid methyl 2-oxopropyl ester; MPC-1304; Sapresta; 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-methyl 5-(2-oxopropyl) ester. Grade: 99%. CAS No. 86780-90-7. Molecular formula: C19H20N2O7. Mole weight: 388.37. | |
| Arasertaconazole | Arasertaconazole is the (R)-enantiomer of Sertaconazole, an imidazole antifungal agent that inhibits the synthesis of ergosterol, an essential cell wall component of fungi. Synonyms: (R)-Sertaconazole; 1-[(2R)-2-[(7-Chlorobenzo[b]thien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-Imidazole. Grade: > 95%. CAS No. 583057-48-1. Molecular formula: C20H15Cl3N2OS. Mole weight: 437.78. | |
| Arasertaconazole-d3 | Isotope labelled arasertaconazole. Arasertaconazole is the (R)-enantiomer of sertaconazole, Sertaconazole is an antifungal medication of the imidazole class. It is available as a cream to treat skin infections. Grade: > 95%. Molecular formula: C20H12Cl3N2OSD3. Mole weight: 440.8. | |
| ara UTP | Ara UTP, a potent nucleotide analog known for its excellent substrate activity towards RNA polymerases, has garnered significant research interest in the field of medical science. Its diverse applicability ranges from elucidating RNA editing and splicing mechanisms to synthesizing modified RNA molecules, thus serving as an invaluable tool for researchers. Furthermore, the promising antiviral activity of Ara UTP has been explored as a potential therapeutic option for hepatitis C virus infections, opening up new avenues for clinical intervention. Synonyms: 1-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-arabinofuranosyl]-2,4(1H,3H)-pyrimidinedione; 1-β-D-Arabinofuranosyluracil-5'-triphosphate; Ara-UTP; ara-UTP; Uracil arabinoside triphosphate; arabinofuranosyluridine triphosphate. Grade: ≥95%. CAS No. 60102-52-5. Molecular formula: C9H15N2O15P3. Mole weight: 484.14. | |
| Ara-UTP sodium salt | Ara-UTP can be used as an antiviral nucleotide. Synonyms: 1-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-arabinofuranosyl]-2,4(1H,3H)-pyrimidinedione sodium salt; 1-β-D-Arabinofuranosyluracil-5'-triphosphate sodium salt; ara UTP sodium salt; Uracil arabinoside triphosphate sodium salt; arabinofuranosyluridine triphosphate sodium salt. Grade: ≥90% by AX-HPLC. Molecular formula: C9H15N2O15P3 (free acid). Mole weight: 484.14 (free acid). | |
| ARB-272572 | ARB-272572 is a potent and selective PD-L1 inhibitor with an IC50 value of 400 pM. Synonyms: PD-L1 inhibitor compound A; N,N'-(2,2'-Dimethylbiphenyl-3,3'-diyl)bis(5-((2-hydroxyethylamino)methyl)picolinamide). Grade: 99%. CAS No. 2368182-63-0. Molecular formula: C32H36N6O4. Mole weight: 568.67. | |
| Arbaclofen placarbil | Arbaclofen placarbil is a prodrug of R-baclofen. It is a GABA B receptor agonist. Arbaclofen was being developed as a potential treatment for patients with GERD and spasticity due to multiple sclerosis. However, development was terminated because of unsuccessful results in phase III clinical trials. Uses: Gerd;spasticity. Synonyms: XP19986; XP-19986; XP 19986; Arbaclofen placarbil; (R)-3-(4-chlorophenyl)-4-((((S)-1-(isobutyryloxy)-2-methylpropoxy)carbonyl)amino)butanoic acid. Grade: 98%. CAS No. 847353-30-4. Molecular formula: C19H26ClNO6. Mole weight: 399.87. | |
| Arbidol Impurity 1 | Arbidol Impurity 1 is an impurity of Arbidol, a medicinal agent for treating viral infections. Synonyms: Demethyl Arbidol; 1130901-04-0. CAS No. 1130901-04-0. Molecular formula: C21H23BrN2O3S. Mole weight: 463.39. | |
| Arbidol Impurity 10 | Arbidol Impurity 10 is an impurity of Arbidol, a medicinal agent for treating viral infections. CAS No. 1312943-26-2. Molecular formula: C15H14Br3NO4. Mole weight: 511.99. | |
| Arbidol Impurity 11 | Arbidol Impurity 11 is an impurity of Arbidol, a medicinal agent for treating viral infections. CAS No. 1312943-27-3. Molecular formula: C15H14Br3NO4. Mole weight: 511.99. | |
| Arbidol Impurity 12 | Arbidol Impurity 12 is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C15H15Br2NO4. Mole weight: 433.09. | |
| Arbidol Impurity 13 | Arbidol Impurity 13 is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C13H13Br2NO3. Mole weight: 391.05. | |
| Arbidol Impurity 14 | Arbidol Impurity 14 is an impurity of Arbidol, a medicinal agent for treating viral infections. CAS No. 1332614-17-1. Molecular formula: C21H23BrN2O3S. Mole weight: 463.39. | |
| Arbidol Impurity 2 | Arbidol Impurity 2 is an impurity of Arbidol, a medicinal agent for treating viral infections. Synonyms: 25900-97-4; Arbidol Impurity 2; Oprea1_017206; Oprea1_800726; SCHEMBL12567455. CAS No. 25900-97-4. Molecular formula: C22H26N2O3S. Mole weight: 398.52. | |
| Arbidol Impurity 3 | Arbidol Impurity 3 is an impurity of Arbidol, a medicinal agent for treating viral infections. CAS No. 958450-23-2. Molecular formula: C22H23BrN2O3S. Mole weight: 475.40. | |
| Arbidol Impurity 4 | Arbidol Impurity 4 is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C20H20BrNO3S. Mole weight: 434.35. | |
| Arbidol Impurity 6 | Arbidol Impurity 6 is an impurity of Arbidol, a medicinal agent for treating viral infections. CAS No. 2107765-51-3. Molecular formula: C13H15NO3. Mole weight: 233.26. | |
| Arbidol Impurity 7 | Arbidol Impurity 7 is an impurity of Arbidol, a medicinal agent for treating viral infections. Synonyms: 5-Acetoxy-6-bromo-2-bromomethyl-1-methyl-1H-indole-3-carboxylic acid, ethyl ester. Grade: 98 %. CAS No. 110543-98-1. Molecular formula: C15H15Br2NO4. Mole weight: 433.09. | |
| Arbidol Impurity 9 | Arbidol Impurity 9 is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C15H16BrNO4. Mole weight: 354.20. | |
| Arbidol Impurity A | Arbidol Impurity A is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C20H21BrN2O3S. Mole weight: 449.36. | |
| Arbidol Impurity B | 6-bromo-1,2,4-trimethyl-1H-indol-5-ol is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C11H12BrNO. Mole weight: 254.12. | |
| Arbidol Impurity C | Arbidol Impurity C is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C12H13BrN2O2. Mole weight: 297.15. | |
| Arbidol Impurity D | Arbidol Impurity D is an impurity of Arbidol, a medicinal agent for treating viral infections. Synonyms: 1,2,3,4-tetramethyl-1H-indol-5-ol. Molecular formula: C12H15NO. Mole weight: 189.25. | |
| Arbidol Impurity E | Arbidol Impurity E is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C12H13Br2NO. Mole weight: 347.05. | |
| Arbidol Impurity F HCl | Arbidol Impurity F HCl is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C20H22BrClN2O3S. Mole weight: 485.82. | |
| Arbidol Impurity I | A Impurity of Arbidol. Synonyms: ethyl 6,7-dibromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylthio)methyl)-1H-indole-3-carboxylate. Grade: > 95%. CAS No. 153633-10-4. Molecular formula: C22H24Br2N2O3S. Mole weight: 556.32. | |
| Arbidol Impurity J | Arbidol Impurity J is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C16H20Br2N2O3. Mole weight: 448.15. | |
| Arbidol Sulfone | A Impurity of Arbidol. Synonyms: 6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylsulfonyl)methyl]-1H-indole-3-carboxylic Acid Ethyl Ester. Grade: > 95%. CAS No. 151455-32-2. Molecular formula: C22H25BrN2O5S. Mole weight: 509.42. | |
| Arbidol Sulfoxide | A Impurity of Arbidol. Synonyms: 6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylsulfinyl)methyl]-1H-indole-3-carboxylic Acid Ethyl Ester. Grade: > 95%. CAS No. 151455-33-3. Molecular formula: C22H25BrN2O4S. Mole weight: 493.42. | |
| Arbutamine | Arbutamine is β-adrenergic receptor originated by SICOR. It is a cardiac stimulant. Arbutamine is a synthetic catecholamine with positive chronotropic and inotropic properties and be applicated in echocardiography and diagnostic coronary angiography. Arbutamine can bind to and activate β-1 adrenergic receptors in the myocardium, so it can increase heart rate and force of myocardial contraction. Arbutamine is an approved drug for the treatment of Coronary artery disease. Uses: Coronary artery disease. Synonyms: Genesa; Arbutaminum; Arbutamina; UNII-B07L15YAEV; CHEBI:50580; ; 125251-66-3(Hydrochloride); 4-[(1R)-1-hydroxy-2-[4-(4-hydroxyphenyl)butylamino]ethyl]benzene-1,2-diol. Grade: 98%. CAS No. 128470-16-6. Molecular formula: C18H23NO4. Mole weight: 317.38. | |
| AR-C 102222 | AR-C 102222 has been found to be an iNOS inhibitor and show antinociceptive and anti-inflammatory activity in rodent pain models. Synonyms: AR-C 102222; AR C 102222; ARC 102222; ARC102222; 5-[(4'-Amino-5',8'-difluorospiro[piperidine-4,2'(1'H)-quinaxolin]-1-yl)carbonyl]-2-pyridinecarbonitrile hydrochloride. Grade: ≥98% by HPLC. CAS No. 253771-21-0. Molecular formula: C19H16F2N6O.HCl. Mole weight: 418.83. | |
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