BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| AR-C102222 hydrochloride | AR-C102222 is a potent, orally active and highly selective inducible nitric oxide synthase (iNOS) inhibitor, with an IC50 of 37 nM. Synonyms: 5-[(4'-Amino-5',8'-difluorospiro[piperidine-4,2'(1'H)-quinaxolin]-1-yl)carbonyl]-2-pyridinecarbonitrile Hydrochloride (1:1). Grade: ≥98%. CAS No. 1781934-50-6. Molecular formula: C19H17ClF2N6O. Mole weight: 418.83. |  |
| AR-C117977 | AR-C117977 is a potent MCT1 inhibitor that inhibited the rat MLR and was more potent than cyclosporin A (CsA). AR-C117977 can reduce vimmune responses both in vitro and in vivo, maintains long-term graft survival, and induces operational tolerance. Synonyms: 5-((3-hydroxypropyl)thio)-1-isobutyl-3-methyl-6-(naphthalen-1-ylmethyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; AR-C-117977; AR-C 117977. Grade: >98%. CAS No. 216685-07-3. Molecular formula: C25H28N2O3S2. Mole weight: 468.63. | |
| AR-C 118925XX | AR-C126313, a thiouracil derivative, has been found to be a competitive P2Y2 receptor antagonist and could inhibit P2Y2 receptor-induced β-arrestin translocation in vitro. Synonyms: AR-C126313; ARC126313; AR C126313; 5-[[5-(2,8-Dimethyl-5H-dibenzo[a,d]cyclohepten-5-yl)-3,4-dihydro-2-oxo-4-thioxo-1(2H)-pyrimidinyl]methyl]-N-2H-tetrazol-5-yl-2-furancarboxamide. Grade: ≥97% by HPLC. CAS No. 216657-60-2. Molecular formula: C28H23N7O3S. Mole weight: 537.59. | |
| AR-C124910XX-N-Glucuronide | An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and compared with clopidogrel will result in a lower risk of recurrent thrombotic events in a broad patient population with ACS and that this result can be achieved with a clinically acceptable bleeding rate and overall safety profile. Synonyms: 6-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)(5-(propylthio)-3-((1R,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grade: > 95%. Molecular formula: C27H32F2N6O9S. Mole weight: 654.65. | |
| AR-C124910XX-O-Glucuronide | An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist ticagrelor and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: 6-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)(5-(propylthio)-3-((1R,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grade: > 95%. Molecular formula: C27H32F2N6O9S. Mole weight: 654.65. | |
| AR-C141990 hydrochloride | AR-C141990 hydrochloride is a potent lactate transporters (monocarboxylate transporters; MCTs) inhibitor with pKi values of 7.6, 6.6 for MCT-1 and MCT-2, respectively. Synonyms: AR-C 141990 hydrochloride. CAS No. 2250019-94-2. Molecular formula: C26H29ClN4O4S. Mole weight: 529.05. | |
| AR-C155858 | AR-C155858 is a novel inhibitor of the monocarboxylate transporters (MCTs) MCT1 and MCT2, but exhibits no activity at MCT4. It can be used to probe MCTs' roles in the metabolic studies. Besides, AR-C155858 was found to have immunosuppressive activity and can inhibit the proliferation of T-lymphocytes. Synonyms: ARC155858; AR-C155858; ARC 155858. Grade: >98%. CAS No. 496791-37-8. Molecular formula: C21H27N5O5S. Mole weight: 461.53. | |
| ARC 239 | ARC239 dihydrochloride is a potent and selective α2 B adrenoceptor antagonist. It is used as an α-adrenoceptor blocking drug. It competitively antagonizes pressor responses to adrenaline and inhibits pressor responses to noradrenaline, tyramine, phenylephrine and dimethylphenylpiperazinium. Uses: Arc239 dihydrochloride is used as an α-adrenoceptor blocking drug. Synonyms: ARC239 dihydrochloride; ARC 239 dihydrochloride; ARC-239 dihydrochloride; 2-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-4,4-dimethyl-1,3-(2H,4H)-isoquinolindione dihydrochloride; AR-C239 Dihydrochloride. Grade: 98%. CAS No. 67339-62-2. Molecular formula: C24H29N3O3. Mole weight: 407.5. | |
| ARC 239 dihydrochloride | The hydrochloride salt form of ARC 239, which has been found to be an α2B adrenoceptor antagonist as well as a norepinephrine-serotonin reuptake inhibitor. Uses: Adrenergic alpha-antagonists. Synonyms: ARC 239 dihydrochloride; ARC239 dihydrochloride; ARC-239 dihydrochloride; 2-[2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl]-4,4-dimethyl-1,3-(2H,4H)-isoquinolindione dihydrochloride. Grade: ≥98% by HPLC. CAS No. 55974-42-0. Molecular formula: C24H29N3O3.2HCl. Mole weight: 480.43. | |
| AR-C 66096 tetrasodium salt | The sodium salt form of AR-C 66096, which has been found to be a P2Y12 receptor antagonist and could be probably used as an antithrombotic agent. Synonyms: ARL-66096; ARL 66096; ARL66096; 2-(Propylthio)adenosine-5'-O-(β,γ-difluoromethylene)triphosphate tetrasodium salt. Grade: ≥98% by HPLC. CAS No. 145782-74-7. Molecular formula: C14H18F2N5Na4O12P3S. Mole weight: 703.26. | |
| ARCA ammonium salt | m27,3'-OGP3G (ARCA Cap Analog) - solution is a valuable tool in the biomedical field, specifically in drug discovery and gene expression studies. m27,3'-OGP3G acts as an efficient cap analog, promoting mRNA capping reactions in various experimental settings. It finds applications in RNA synthesis, mRNA translation and cellular processes related to RNA metabolism. Its utility extends to investigating viral infections, cancer therapeutics and molecular biology research. Synonyms: ARCA Ammonium; Anti Reverse Cap Analog ammonium salt; m7(3'-O-methy)G(5')ppp(5')G ammonium salt; 3'-O-Me-m7G(5')ppp(5')G ammonium salt; m27, 3'-OGP3G (ARCA Cap Analog) ammonium salt; 3'-O-Methyl-m7GpppG ammonium salt; ARCA (anti-reverse cap analog) ammonium salt; m27,3'OGpppG ammonium salt; N7-Methyl-3'-O-Methyl-Guanosine-5'-Triphosphate-5'-Guanosine ammonium salt. Grade: ≥95% by HPLC. Molecular formula: C22H31N10O18P3 (free acid). Mole weight: 816.46 (free acid). | |
| Arcaine sulfate | Arcaine sulfate is the sulfate salt of arcaine, which is a potent, competitive and novel antagonist of the polyamine site on the NMDA receptor. Synonyms: N,N'-1,4-Butanediylbisguanidine sulfate; 1,4-Diguanidinobutane sulfate salt. Grade: ≥99% by HPLC. CAS No. 14923-17-2. Molecular formula: C6H18N6SO4. Mole weight: 270.31. | |
| ARCA Sodium | ARCA Sodium, a potent inhibitor of the Nav1.5 cardiac sodium channel, is adeptly utilized in mitigating arrhythmias, such as atrial fibrillation. Additionally, it exhibits promise as a therapeutic agent for the management of chronic pain conditions. Synonyms: ARCA, sodium salt; Anti Reverse Cap Analog sodium salt; m7(3'-O-methy)G(5')ppp(5')G sodium salt; 3'-O-Me-m7G(5')ppp(5')G sodium salt; m27, 3'-OGP3G (ARCA Cap Analog) sodium salt; 3'-O-Methyl-m7GpppG sodium salt; ARCA (anti-reverse cap analog) sodium salt; m27,3'OGpppG sodium salt; N7-Methyl-3'-O-Methyl-Guanosine-5'-Triphosphate-5'-Guanosine, sodium salt. Grade: ≥95% by HPLC. Molecular formula: C22H31N10O18P3 (free acid). Mole weight: 816.46 (free acid). | |
| ARCC-4 | ARCC-4 is a PROTAC, acting as an androgen receptor degrader. ARCC-4 is a low-nanomolar androgen receptor degrader able to degrade about 95% of cellular androgen receptors. It inhibits prostate tumor cell proliferation, degrades clinically relevant androgen receptor point mutants and unlike enzalutamide, retains antiproliferative effect in a high androgen environment. Synonyms: ARCC-4; 1973403-00-7; (2S,4R)-1-((S)-2-(2-(4-((4'-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-[1,1'-biphenyl]-4-yl)oxy)butoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide; CHEMBL4540528; SCHEMBL17946930; DUPAJELXESPTNF-PPZGWQTASA-N; AKOS040741162; MS-31874; HY-130492; CS-0108331; EN300-7526556; Z3482428589; O1-(ABM-14 ether), O4-(Methylcarboxamide with AHPC) Butanediol; (2S,4R)-1-[(2S)-2-(2-{4-[(4'-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl}-[1,1'-biphenyl]-4-yl)oxy]butoxy}acetamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide. Grade: 99%. CAS No. 1973403-00-7. Molecular formula: C53H56F3N7O7S2. Mole weight: 1024.18. | |
| archaeosine | Archaeosine, an essential compound, holds immense significance in the realm of biomedicine due to its potential therapeutic efficacy in a diverse array of ailments. A pivotal player in crafting targeted medications for cancer, neurological maladies, and infectious conditions, this product assumes a critical role in the advanced pharmaceutical landscape. Synonyms: 1H-Pyrrolo[2,3-d]pyrimidine-5-carboximidamide, 2-amino-4,7-dihydro-4-oxo-7-b-D-ribofuranosyl-; 2-Amino-4,7-dihydro-4-oxo-7-beta-D-ribofuranosyl-1H-pyrrolo(2,3-d)pyrimidine-5-carboximidamide; 2-amino-4-oxo-7-(beta-D-ribofuranosyl)-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide. CAS No. 148608-52-0. Molecular formula: C12H16N6O5. Mole weight: 324.3. | |
| Arcitumomab | Arcitumomab is a humanized monoclonal antibody raised against human carcinoembryonic antigen (CEA). Arcitumomab is used as a diagnostic imaging agent for colorectal cancers. Synonyms: IMMU 4; CEA-Scan; Immunoglobulin G1, anti-(human carcinoembryonic antigen) Fab' fragment (mouse monoclonal IMMU-4 γ1-chain), disulfide with mouse monoclonal IMMU-4 light chain. Grade: 95%. CAS No. 154361-48-5. | |
| Arcyriaflavin A | Arcyriaflavin A is a potent dual target agent of calcium/calmodulin-dependent protein kinase II (CaMKII) and cyclin-dependent kinase 4 (CDK4). Its IC50 values are 140 nM and 25 nM for CDK4 and CaMKII respectively, which is selective over protein kinase A (PKA) and PKC in vitro. It inhibits proliferation of HCT116 and NCI H460 human carcinoma cells and replication of human cytomegalovirus (HCMV) in vitro. It also inhibits proliferation and induces apoptosis of endometriotic cyst stromal cells (ECSCs). Synonyms: Arcyriaflavin A; Arcyriaflavin-A; 12,13-Dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione; 6,7,12,13-Tetrahydro-5H-Indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione; Maleimide Indolocarbazole. Grade: ≥98% by HPLC. CAS No. 118458-54-1. Molecular formula: C20H11N3O2. Mole weight: 325.32. | |
| ARD-2128 | ARD-2128 is a highly potent, orally bioavailable PROTAC androgen receptor degrader. It effectively reduces AR protein, suppresses AR-regulated genes in tumor tissues, and inhibits growth of tumor without signs of toxicity. Synonyms: ARD2128; ARD 2128; N-[(1r,3r)-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]piperidin-4-yl]methyl]piperazin-1-yl]benzamide. Grade: ≥98%. CAS No. 2222111-87-5. Molecular formula: C45H50ClN7O6. Mole weight: 820.37. | |
| ARD-2585 | ARD-2585 is an exceptionally potent and orally active PROTAC degrader of androgen receptor for the treatment of advanced prostate cancer. Synonyms: Benzamide, N-[trans-4-[(3-chloro-4-cyanophenyl)methylamino]cyclohexyl]-4-[4-[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-3-azetidinyl]-1-piperazinyl]-; N-((1r,4r)-4-((3-chloro-4-cyanophenyl)(methyl)amino)cyclohexyl)-4-(4-(1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)azetidin-3-yl)piperazin-1-yl)benzamide; N-[trans-4-[(3-Chloro-4-cyanophenyl)methylamino]cyclohexyl]-4-[4-[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-3-azetidinyl]-1-piperazinyl]benzamide; ARD 2585; ARD2585. CAS No. 2757422-79-8. Molecular formula: C41H43ClN8O5. Mole weight: 763.28. | |
| ARD-266 | ARD-266 is a highly potent and VHL E3 ligase-based androgen receptor (AR) PROTAC degrader. ARD-266 effectively induces the degradation of AR protein in AR-positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines (DC50s = 0.2-1 nM). Synonyms: 2-Pyrrolidinecarboxamide, N-[(1S)-3-[4-[2-[4-[[[trans-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]amino]carbonyl]phenyl]ethynyl]-1-piperidinyl]-3-oxo-1-phenylpropyl]-4-hydroxy-1-[(2R)-3-methyl-2-(3-methyl-5-isoxazolyl)-1-oxobutyl]-, (2S,4R)-; (2S,4R)-N-((S)-3-(4-((4-(((1r,3r)-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl)carbamoyl)phenyl)ethynyl)piperidin-1-yl)-3-oxo-1-phenylpropyl)-4-hydroxy-1-((R)-3-methyl-2-(3-methylisoxazol-5-yl)butanoyl)pyrrolidine-2-carboxamide; (2S,4R)-N-[(1S)-3-[4-[2-[4-[[[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]amino]carbonyl]phenyl]ethynyl]-1-piperidinyl]-3-oxo-1-phenylpropyl]-4-hydroxy-1-[(2R)-3-methyl-2-(3-methyl-5-isoxazolyl)-1-oxobutyl]-2-pyrrolidinecarboxamide. Grade: ≥95%. CAS No. 2666951-70-6. Molecular formula: C52H59ClN6O7. Mole weight: 915.51. | |
| Arecaidine propargyl ester tosylate | Arecaidine propargyl ester tosylate is a potent muscarinic receptor agonist. It displays some selectivity for cardiac versus ileal M2 receptors. Synonyms: N-Methyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid propargyl ester tosylate. CAS No. 147202-94-6. Molecular formula: C17H21NO5S. Mole weight: 351.42. | |
| ARG1-IN-1 | ARG1-IN-1 is a human arginase 1 inhibitor with an IC50 of 29 nM. Synonyms: ARG1-IN-1; CHEMBL4639162; 2376189-62-5; SCHEMBL2723760; BDBM50538518; AKOS040757613; HY-145331; CS-0371523. CAS No. 2376189-62-5. Molecular formula: C11H21BN2O4. Mole weight: 256.11. | |
| Argadin | Argadin is a biomedical product used in the research of chronic obstructive pulmonary disease (COPD). Synonyms: 4-[(1S,4R,10S,13S,16S,18R)-10-[3-[[acetamido(amino)methylidene]amino]propyl]-18-hydroxy-16-(1H-imidazol-5-ylmethyl)-3,9,12,15,20-pentaoxo-2,8,11,14,17-pentazatricyclo[15.2.1.04,8]icosan-13-yl]butanoic acid. CAS No. 289665-92-5. Molecular formula: C29H42N10O9. Mole weight: 674.71. | |
| Argatroban | Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. Uses: Antithrombins; platelet aggregation inhibitors. Synonyms: (2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid. Grade: >98%. CAS No. 74863-84-6. Molecular formula: C23H36N6O5S. Mole weight: 508.63. | |
| Argatroban Impurity 6 | A metabolite of Argatroban. Synonyms: 5-Quinolinesulfonyl chloride, 3-methyl-. Grade: > 95%. CAS No. 94975-84-5. Molecular formula: C10H8ClNO2S. Mole weight: 241.7. | |
| Argatroban Impurity A | A metabolite of Argatroban. Synonyms: (2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-2-[[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic Acid. Grade: > 95%. CAS No. 951130-92-0. Molecular formula: C23H32N6O5S. Mole weight: 504.61. | |
| Argatroban Impurity B | Argatroban Impurity B is an impurity of Argatroban, which is a synthetic thrombin inhibitor and antithrombotic agent. Synonyms: Argatroban Impurity B (Mixture of Diastereomers); 4-Methylpiperidine-2-carboxylic Acid, (2R,4R)-1-((2S)-5-amino-2-((3-methyl-1,2,3,4-tetrahydroquinoline)-8-sulfonamido)pentanoyl)-. Grade: 95%. CAS No. 188659-43-0. Molecular formula: C22H34N4O5S. Mole weight: 466.59. | |
| Argatroban (L,2R,4S)-isomer | Argatroban (L,2R,4S)-isomer is an impurity of Argatroban, a synthetic thrombin inhibitor and antithrombotic agent. Synonyms: (2R,4S)-4-methyl-1-(((3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonyl)-L-arginyl)piperidine-2-carboxylic acid; (2R,4S)-1-((2S)-5-Guanidino-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl)-4-methylpiperidine-2-carboxylic Acid; Argatroban (L,2R,4S)-Isomer (Mixture of Diastereomers). CAS No. 189264-04-8. Molecular formula: C23H36N6O5S. Mole weight: 508.63. | |
| Argatroban monohydrate | Argatroban is an anticoagulant that acts as a potent, seletive, univalent direct inhibitor of thrombin. Argatroban was approved in 2000 for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia (HIT). Synonyms: (2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(3R)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonylamino]pentanoyl]-4-methyl-piperidine-2-carboxylic acid hydrate; MCI-9038; MCI 9038; MCI9038; MD805; MD-805; MD 805; DK-7419; DK 7419; DK7419; GN1600; GN-1600; GN 1600; MMTQAP; MPQA; OM 805; Slonnon; Argipidine; Argatroban monohydrate. Grade: 98%. CAS No. 141396-28-3. Molecular formula: C23H38N6O6S. Mole weight: 526.65. | |
| Argatroban Related Compound | An intermediate in the preparation of Argatroban. Synonyms: Ethyl (2S,4S)-4-Methylpipecolate; (2S,4S)-4-Methyl-2-piperidinecarboxylic Acid Ethyl Ester; (2S-trans)-4-Methyl-2-piperidinecarboxylic Acid Ethyl Ester. Grade: > 95%. CAS No. 78306-52-2. Molecular formula: C9H17NO2. Mole weight: 171.24. | |
| Argatroban Related Compound 1 | A metabolite of Argatroban. Synonyms: Ethyl (2R,4S)-4-Methylpipecolate. Grade: > 95%. CAS No. 79199-61-4. Molecular formula: C9H17NO2. Mole weight: 171.24. | |
| Argatroban Related Compound 2 | A metabolite of Argatroban. Synonyms: Ethyl (2S,4R)-4-Methylpipecolate. Grade: > 95%. CAS No. 79199-62-5. Molecular formula: C9H17NO2. Mole weight: 171.24. | |
| Argatroban Related Compound B monohydrochloride | An impurity of Argatroban. Argatroban is a direct thrombin inhibitor used primarily for the treatment and prevention of blood clots in patients with heparin-induced thrombocytopenia (HIT) or those undergoing percutaneous coronary interventions. Uses: Argatroban intermediate. Synonyms: Argatroban Intermediate; (2R,4R)1-[(2S)2-Amino-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic Acid Ethyl Ester Hydrochloride; 2-Piperidinecarboxylic acid, 1-[(2S)-2-amino-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-, ethyl ester, hydrochloride (1:1), (2R,4R)-; 2-Piperidinecarboxylic acid, 1-[2-amino-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-, ethyl ester, monohydrochloride, [2R-[1(S*),2α,4β]]-; Ethyl (2R,4R)-1-(Nitroglycerine-nitro-L-arginyl)-4-methyl-piperidinecarboxylate hydrochloride; Argatroban USP Related Compound B hydrochloride; Argatroban Impurity 13 HCl. Grade: 95%. CAS No. 74874-08-1. Molecular formula: C15H28N6O5.HCl. Mole weight: 408.88. | |
| Argatroban Related Impurity 2 | A metabolite of Argatroban. Synonyms: (2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[[(3R)-1,2,3,4-tetrahydro-3-methyl-8-quinolinyl]sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid. Grade: > 95%. CAS No. 189264-02-6. Molecular formula: C23H36N6O5S. Mole weight: 508.64. | |
| Argatroban USP Related Compound B | An impurity of Argatroban. Argatroban is a direct thrombin inhibitor used primarily for the treatment and prevention of blood clots in patients with heparin-induced thrombocytopenia (HIT) or those undergoing percutaneous coronary interventions. Synonyms: {2R-[1(S*)-2α,4β]-1-{2-Amino-5-{[imino-(nitroamino)-methyl]-amino}-1-oxopentyl}-4-methyl-2-piperidinecarboxylic acid ethyl ester; Ethyl (4R)-1-[N8-nitro-L-arginyl]-4-methylpiperidine-2-carboxylate; USP Argatroban Related Compound B; Argatroban related compound B; (2R,4R)1-[(2S)2-Amino-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic Acid Ethyl Ester; (2R,4R)-Ethyl 1-((S)-2-amino-5-(3-nitroguanidino)pentanoyl)-4-methylpiperidine-2-carboxylate; Argatroban Impurity D. Grade: ≥95%. CAS No. 79672-38-1. Molecular formula: C15H28N6O5. Mole weight: 372.42. | |
| Arg-Gly-Asp-Cys acetate | Arg-Gly-Asp-Cys, a fibronectin binding motif to cell adhesion molecules, inhibits platelet aggregation and fibrinogen binding. Synonyms: L-arginyl-glycyl-L-alpha-aspartyl-L-cysteine; RGDC peptide. Molecular formula: C17H31N7O9S. Mole weight: 509.54. | |
| Arg-Gly-Asp-Ser acetate | Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. It is a tetrapeptide found on fibronectin, fibrinogen α, and von Willebrand factor, but not vitronectin or collagen. It decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9. It inhibits thrombin-induced binding of platelets to fibronectin, fibrinogen α, and von Willebrand factor. It promotes cell attachment and abrogates apoptosis via the mitochondrial pathway in osteoblasts in vitro. It also blocks the attachment of certain pathogens to cells. Molecular formula: C17H31N7O10. Mole weight: 493.47. | |
| Arg-Gly-Glu-Ser | Arg-Gly-Glu-Ser, a RGD-related peptide, is a control for the RGDS ihibitory activity on fibrinogen binding to activated platelets. Synonyms: H-Arg-Gly-Glu-Ser-OH; L-arginyl-glycyl-L-alpha-glutamyl-L-serine; (4S)-4-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-5-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-5-oxopentanoic acid; RGES. Molecular formula: C16H29N7O8. Mole weight: 447.45. | |
| Arg-Gly-Glu-Ser acetate salt | Arg-Gly-Glu-Ser acetate salt is a RGD-related peptide, which is a control of RGDS to inhibit the binding activity of fibrinogen and activated platelet. Synonyms: (6S,12S,15S)-1,6-diamino-12-(2-carboxyethyl)-15-(hydroxymethyl)-1-imino-7,10,13-trioxo-2,8,11,14-tetraazahexadecan-16-oic acid compound with acetic acid (1:1). CAS No. 159002-32-1. Molecular formula: C18H33N7O10. Mole weight: 507.49. | |
| Arginase inhibitor 1 | Arginase inhibitor 1 is active in a recombinant cellular assay overexpressing humanarginase I (CHO cells). It is 28% orally bioavailable and significantly reduces the infarct size in a rat model of myocardial ischemia/reperfusion injury. Synonyms: Arginase inhibitor 1. Grade: >98%. CAS No. 1345808-25-4. Molecular formula: C13H27BN2O4. Mole weight: 286.18. | |
| Arginine Tidiacicate | Arginine Tidiacicate is an impurity of arginine, which is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. Synonyms: Tiadilon; (S)-2-Amino-5-guanidinopentanoic acid thiazolidine-2,4-dicarboxylic acid (1:1); Tidiacic arginine. CAS No. 30986-62-0. Molecular formula: C11H21N5O6S. Mole weight: 351.38. | |
| Arginine vasotocin trifluoroacetate salt | Arginine vasotocin (AVT) is the non-mammalian homolog of arginine vasopressin (AVP) and serves as an important modulator of social behavior in addition to its peripheral functions related to osmoregulation, reproductive physiology, and stress hormone release. AVT is aslo homologous to arginine vasopressin in mammals and is endogenously released from the neurohypophysis primarily in response to hyperosmotic stimuli and associated cellular dehydration. Arginine vasotocin is a nonapeptide hormone agonist of the AVT receptor with EC50 of 13 nM for eliciting membrane. Synonyms: [Arg8]-Vasotocin; AVT. Grade: ≥95%. Molecular formula: C43H67N15O12S2·xCF3COOH. Mole weight: 1050.22. | |
| Arhalofenate | Arhalofenateis, also known as JNJ-39659100 and MBX102, as an uricosuric agent it is a selective, partial PPAR-γ agonist. Synonyms: 2-acetamidoethyl (2R)-2-(4-chlorophenyl)-2-[3-(trifluoromethyl)phenoxy]acetate; JNJ-39659100; JNJ39659100; JNJ 39659100; MBX102; MBX-102; MBX 102; Arhalofenate. Grade: >98%. CAS No. 24136-23-0. Molecular formula: C19H17ClF3NO4. Mole weight: 415.79. | |
| Arimoclomol maleate | Arimoclomol is a heat shock protein amplifier. It has been granted Fast Track designation by FDA for the treatment of myotrophic lateral sclerosis (ALS). Synonyms: (2R)-Arimoclomol Maleic Acid. CAS No. 289893-26-1. Molecular formula: C18H24ClN3O7. Mole weight: 429.9. | |
| Aripiprazole Bromo Impurity | A metabolite of Aripiprazole. Synonyms: 7-(4-Bromobutoxy)-quinoline-2(1H)-one. Grade: > 95%. CAS No. 203395-59-9. Molecular formula: C13H14BrNO2. Mole weight: 296.17. | |
| Aripiprazole Diquinoline Butanediol Impurity | A metabolite of Aripiprazole, an atypical antipsychotic used to treat schizophrenia. Synonyms: 7,7'-(propane-1,3-diylbis(oxy))bis(3,4-dihydroquinolin-2(1H)-one). Grade: > 95%. CAS No. 882880-12-8. Molecular formula: C22H24N2O4. Mole weight: 380.45. | |
| Aripiprazole EP Impurity A | A metabolite of Aripiprazole, an atypical antipsychotic used to treat schizophrenia. Synonyms: 3,4-Dihydro-7-hydroxyquinoline-2(1H)-one. Grade: > 95%. CAS No. 22246-18-0. Molecular formula: C9H9NO2. Mole weight: 163.17. | |
| Aripiprazole EP Impurity B | An impurity of Aripiprazole, an atypical antipsychotic used to treat schizophrenia. Synonyms: DCPP; 1-(2,3-Dichlorophenyl)-piperazine; 2,3-Dichlorophenylpiperazine. CAS No. 41202-77-1. Molecular formula: C10H12Cl2N2. Mole weight: 231.12. | |
| Aripiprazole EP Impurity C | An impurity of Aripiprazole, an atypical antipsychotic used to treat schizophrenia. Synonyms: Deschloroaripiprazole; Deschloro aripiprazole; Aripiprazole 3-Deschloro Impurity. CAS No. 203395-81-7. Molecular formula: C23H28ClN3O2. Mole weight: 413.94. | |
| Aripiprazole EP Impurity D | An impurity of Aripiprazole, an atypical antipsychotic used to treat schizophrenia. Synonyms: 2-Deschloro Aripiprazole; 7-[4-[4-(3-chlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydroquinolin-2(1H)-one. CAS No. 203395-82-8. Molecular formula: C23H28ClN3O2. Mole weight: 413.94. | |
| Aripiprazole EP Impurity E | An impurity of Aripiprazole, an atypical antipsychotic used to treat schizophrenia. Synonyms: Dehydroaripiprazole; Dehydro aripiprazole; 7-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)quinolin-2(1H)-one; Dehydro-aripiprazole; Aripiprazole Related Compound G. Grade: >98%. CAS No. 129722-25-4. Molecular formula: C23H25Cl2N3O2. Mole weight: 446.37. | |
| Aripiprazole EP Impurity F | A metabolite of Aripiprazole, an atypical antipsychotic used to treat schizophrenia. Synonyms: Aripiprazole N1-Oxide; Aripiprazole N-Oxide; Aripiprazole USP Related Compound F; Aripiprazole Related Compound F. Grade: > 95%. CAS No. 573691-09-5. Molecular formula: C23H27Cl2N3O3. Mole weight: 464.38. | |
| Aripiprazole EP Impurity G | A metabolite of Aripiprazole, an atypical antipsychotic used to treat schizophrenia. Synonyms: Aripiprazole Dimer; Aripiprazole Dimer Impurity. Grade: > 95%. CAS No. 1797986-18-5. Molecular formula: C48H56Cl4N6O4. Mole weight: 922.81. | |
| Aripiprazole Hydroxybutyl Impurity | An impurity of Aripiprazole, which is an atypical antipsychotic used to treat schizophrenia. Synonyms: 1-Piperazinebutanol, 4-(2,3-dichlorophenyl)-; 1-(2,3-Dichlorophenyl)-4-(4-hydroxybutyl)piperazine; 4-(2,3-Dichlorophenyl)-1-piperazinebutanol. CAS No. 870765-38-1. Molecular formula: C14H20Cl2N2O. Mole weight: 303.23. | |
| Aripiprazole Impurity 10 | A metabolite of Aripiprazole. Synonyms: Aripiprazole Impurity 10. Grade: > 95%. CAS No. 203395-78-2. Molecular formula: C23H27Cl2N3O2. Mole weight: 448.4. | |
| Aripiprazole Impurity 12 | A metabolite of Aripiprazole. Synonyms: 8-(2,3-Dichlorophenyl)-8-aza-5-azoniaspiro[4.5]decane Bromide. Grade: > 95%. CAS No. 795313-24-5. Molecular formula: C14H19Cl2N2. Br. Mole weight: 286.23 79.90. | |
| Aripiprazole Impurity 16 | A metabolite of Aripiprazole. Synonyms: 7-Hydroxyquinoline-(1H)-2-one. Grade: > 95%. CAS No. 70500-72-0. Molecular formula: C9H7NO2. Mole weight: 161.16. | |
| Aripiprazole impurity 2 | A metabolite of Aripiprazole. Synonyms: Aripiprazole Impurity 2; 1424857-93-1; 1-but-3-enyl-4-(2,3-dichlorophenyl)piperazine1-(But-3-en-1-yl)-4-(2,3-dichlorophenyl)piperazinestarbld0020843. Grade: > 95%. CAS No. 1424857-93-1. Molecular formula: C14H18Cl2N2. Mole weight: 285.22. | |
| Aripiprazole impurity 3 | A metabolite of Aripiprazole. Synonyms: 7-(but-3-en-1-yloxy)-3,4-dihydroquinolin-2(1H)-one. Grade: > 95%. CAS No. 1359829-23-4. Molecular formula: C13H15NO2. Mole weight: 217.27. | |
| Aripiprazole Impurity 4 | A metabolite of Aripiprazole. Synonyms: 1-[4-[(1,2,3,4-Tetrahydro-2-oxo-7-quinolinyl)oxy]butyl] Aripiprazole; 7-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)-1-(4-((2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)oxy)butyl)-3,4-dihydroquinolin-2(1H)-one. Grade: > 95%. CAS No. 1424857-63-5. Molecular formula: C36H42Cl2N4O4. Mole weight: 665.67. | |
| Aripiprazole Impurity 5 | A metabolite of Aripiprazole. Synonyms: 8-Hydroxy-3,4-dihydro-2(1H)-quinolinone. Grade: > 95%. CAS No. 52749-50-5. Molecular formula: C9H9NO2. Mole weight: 163.18. | |
| Aripiprazole Impurity 6 | A metabolite of Aripiprazole. Synonyms: 1-(2,6-dichlorophenyl)piperazine. Grade: > 95%. CAS No. 63386-61-8. Molecular formula: C10H12Cl2N2. Mole weight: 231.13. | |
| Aripiprazole Impurity 9 | A metabolite of Aripiprazole. Synonyms: Aripiprazole N4-Oxide. Grade: > 95%. CAS No. 573691-11-9. Molecular formula: C23H27Cl2N3O3. Mole weight: 464.4. | |
| Aripiprazole lauroxil | Aripiprazole lauroxil is a Dopamine D2 receptor agonist, Serotonin 1A receptor agonist and ISerotonin 2A receptor antagonist under the development of Alkermes plc. Aripiprazole lauroxil is applicated as long-acting injectable atypical antipsychotic for the treatment of schizophrenia. It is an N-acyloxymethyl prodrug of aripiprazole. Uses: Schizophrenia. Synonyms: Aristada; RDC-3317; RDC 3317; RDC3317; UNII-B786J7A343; ALKS 9070; ALKS9070; ALKS-9070; ALKS 9072; ALKS-9072; ALKS9072; [7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-2-oxo-3,4-dihydroquinolin-1-yl]methyl dodecanoate. Grade: 98%. CAS No. 1259305-29-7. Molecular formula: C36H51Cl2N3O4. Mole weight: 660.72. | |
| Aripiprazole Metabolite | A metabolite of Aripiprazole. Synonyms: Aripiprazole Butanoic Acid Impurity. Grade: > 95%. CAS No. 58899-27-7. Molecular formula: C13H15NO4. Mole weight: 249.27. | |
| Aripiprazole Metabolite-d6 | A labelled metabolite of Aripiprazole. Aripiprazole is an atypical antipsychotic indicated for schizophrenia and bipolar disorder. Synonyms: Aripiprazole Butanoic Acid-d6. Grade: > 95%. Molecular formula: C13H9NO4D6. Mole weight: 255.3. | |
| Aripiprazole N,N-Dioxide | An impurity of Aripiprazole, which is an atypical antipsychotic used to treat schizophrenia. Uses: A metabolite of anti-psychotic drug, aripiprazole (a771000). Synonyms: 7-[4-[4-(2,3-Dichlorophenyl)-1,4-dioxido-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone; Aripiprazole Di-N-Oxide. CAS No. 573691-13-1. Molecular formula: C23H27Cl2N3O4. Mole weight: 480.38. | |
| Aripiprazole Related Compound B | A metabolite of Aripiprazole. Synonyms: Aripiprazole IMpurity B. Grade: > 95%. CAS No. 1424858-02-5. Molecular formula: C26H32N2O5. Mole weight: 452.56. | |
| Aripiprazole Related Compound H | An impurity of Aripiprazole, which is an atypical antipsychotic used to treat schizophrenia. Synonyms: Aripiprazole USP RC H; (7-(4-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butoxy}butoxy)-3,4-dihydroquinolin-2(1H)-one). CAS No. 1796928-63-6. Molecular formula: C27H35Cl2N3O3. Mole weight: 520.49. | |
| Aripiprazole USP Related Compound B | An impurity of Aripiprazole, which is an atypical antipsychotic used to treat schizophrenia. Synonyms: 3,4-Dihydro-7-(4-hydroxybutoxy)-2(1H)-quinolinone; 2(1H)-Quinolinone, 3,4-dihydro-7-(4-hydroxybutoxy)-. CAS No. 889443-20-3. Molecular formula: C13H17NO3. Mole weight: 235.28. | |
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