MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| TPO-L | TPO-L is a photoinitiator for the 3D printing of resin that promotes two-photon induced polymerization. The two-photon absorption cross-section spectrum of Lucirin TPO-L shows a maximum of 1.2 GM at 610 nm. Despite its small two-photon absorption cross-section, Lucirin TPO-L exhibits high polymerization quantum yields[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 84434-11-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 g; 500 g. Product ID: HY-W017894. |  |
| TPP-1 | TPP-1 is a potent inhibitor of the PD-1/PD-L1 interaction. TPP-1 binds specifically to PD-L1 with a high affinity (KD=95 nM). TPP-1 inhibits human tumor growth in vivo via reactivating T-cell function[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2426685-25-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P3139. | |
| TPPB | TPPB is a cell-permeable benzolactam-derived protein kinase C (PKC) activator with a Ki of 11.9 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 497259-23-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-12359. | |
| TPPU | TPPU is a soluble epoxide hydrolase (sEH) inhibitor with IC50 values of 37 and 3.7 nM for monkey and human sEH, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1222780-33-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101294. | |
| TP receptor antagonist-3 | TP receptor antagonist-3 (compound 51280) is a potent thromboxane A2 prostanoid (TP) receptor with an IC50 of 15.7 nM against Human TP. TP receptor antagonist-3 can be used for alzheimer's disease, cardiovascular and respiratory diseases, and cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 165537-72-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-176990. | |
| TPT-004 | TPT-004 is a selective and oraly active tryptophan hydroxylases (TPH) inhibitor with IC50s of 77 nM and 16 nM for TPH1 and TPH2, repsectively. TPT-004 exhibits exceptional selectivity for TPH1 compared with other members of the AAAH family. TPT-004 shows efficacy peripheral serotonin attenuation and colorectal tumor growth in mice[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3032648-15-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157014. | |
| TPT-260 Dihydrochloride | TPT-260 Dihydrochloride (NSC55712), a thiophene thiourea derivative, is a retromer complex stabilizer against thermal denaturation (Kd = ~5 μM). TPT-260 Dihydrochloride increases the levels of retromer proteins, shifts amyloid-precursor protein (APP) away from the endosome, and decreases the pathogenic processing of APP. TPT-260 Dihydrochloride inhibits TLR4 upregulation, IKKβ phosphorylation, NF-κB p65 nuclear translocation, and NLRP3 inflammasome formation. TPT-260 Dihydrochloride improves retromer-mediated cargo trafficking, reduces brain infarct area, and decreases amyloid plaque deposition. TPT-260 Dihydrochloride exhibits minimal cytotoxicity to primary microglia at tested concentrations. TPT-260 Dihydrochloride can be used for the research of inflammatory bowel disease, ischemic stroke and Alzheimer's disease[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC55712; TPU-260 Dihydrochloride. CAS No. 2076-91-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13769A. | |
| TR-100 | TR-100 is a small molecule inhibitor of tumor-associated troponin (Tpm). TR-100 affects the interaction of Tpm3.1 with actin filaments by binding to the C-terminal of Tpm3.1, thereby affecting the stability and function of the actin filaments. This mechanism of action allows TR-100 to specifically affect actin filaments in cancer cells without compromising heart muscle function. TR-100 can be used to study the role of Tpm3.1 in cancer cell proliferation and survival and the effects of Tpm3.1 on insulin-stimulated glucose uptake and insulin secretion[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1128165-86-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-124689. | |
| Trabedersen | Trabedersen (AP 12009) is an orally active synthetic antisense phosphorothioate oligodeoxynucleotide that selectively targets human TGFβ2 mRNA. Trabedersen blocks TGFβ2 protein production, enters the nucleus without a transfection vector, and exerts dose-dependent antitumor effects. By reversing TGFβ2-induced immunosuppression and enhancing immune cytotoxicity, Trabedersen exhibits significant antiproliferative, antimigratory, and antimetastatic activities, with favorable safety profiles. Trabedersen is widely used in research related to various solid tumors, including anaplastic astrocytoma, glioblastoma, colorectal tumor, and melanoma[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AP 12009. CAS No. 925681-61-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-142118. | |
| Trabikibart | Trabikibart (CSL311) is a specific inhibitor targeting the βc receptor (CSF2RB) that inhibits signal transduction mediated by GM-CSF, IL-5, and IL-3. Trabikibart exhibits significant anti-inflammatory and anti-edema effects, reduces myeloid cell infiltration, and inhibits inflammatory cell survival. Trabikibart also possesses antiviral immune functions, which alleviate pulmonary inflammation, reverse airway dysfunction and fibrosis, and thereby restore impaired pulmonary function. Trabikibart can be used in research on related diseases such as acute respiratory distress syndrome, viral pneumonia, asthma, and chronic rhinosinusitis with nasal polyps[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CSL311. CAS No. 2643974-98-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990094. | |
| Tracazolate hydrochloride | Tracazolate (ICI 136753) hydrochloride is a potent GABAA receptor modulator. Tracazolate hydrochloride has selectivity for β3 and potentiates α1β1γ2s (EC50=13.2 μM), α1β3γ2 (EC50=1.5 μM). Tracazolate hydrochloride has the potency (EC50) determined by the nature of the third subunit (γ1-3, δ, ε) within the receptor complex. Tracazolate hydrochloride possesses anxiolytic and anticonvulsant activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ICI 136753 hydrochloride. CAS No. 1135210-68-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B1803A. | |
| Tradipitant | Tradipitant (VLY-686) is a neurokinin-1 (NK-1) antagonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VLY-686; LY686017. CAS No. 622370-35-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16732. | |
| Tralokinumab | Tralokinumab (CAT354) is a humanized IgG4 monoclonal antibody that specifically binds to and neutralizes IL-13. Tralokinumab can be used in the research of diseases such as asthma, atopic dermatitis, and pulmonary fibrosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CAT354. CAS No. 1044515-88-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99053. | |
| TRAM-34 | TRAM-34 is a highly selective blocker of intermediate-conductance calcium-activated K+ channel (IKCa1) (Kd=20 nM). Uses: Scientific research. Category: Signaling pathways. CAS No. 289905-88-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13519. | |
| Trametiglue | Trametiglue, a derivative of Trametinib (HY-10999), targets both KSR-MEK and RAF-MEK with unprecedented potency and selectivity via unique interfacial binding interactions[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2666940-97-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153181. | |
| Trametinib | Trametinib (GSK1120212; JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib activates autophagy and induces apoptosis, cross the blood-brain barrier (BBB), used in research related to subarachnoid hemorrhage (SAH)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GSK1120212; JTP-74057. CAS No. 871700-17-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-10999. | |
| Trametinib (DMSO solvate) | Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib (DMSO solvate) activates autophagy and induces apoptosis[1][2]. This product is in solid form, a DMSO solvate, and a stable crystalline form. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GSK-1120212 (DMSO solvate); JTP-74057 (DMSO solvate). CAS No. 1187431-43-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-10999A. | |
| Trametinib (Standard) | Trametinib (Standard) is the analytical standard of Trametinib. This product is intended for research and analytical applications. Trametinib (GSK1120212; JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib activates autophagy and induces apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GSK1120212 (Standard); JTP-74057 (Standard). CAS No. 871700-17-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10999R. | |
| Tramiprosate | Tramiprosate (Homotaurine), an orally active and brain-penetrant natural amino acid found in various species of red marine algae. Tramiprosate binds to soluble Aβ and maintains Aβ in a non-fibrillar form. Tramiprosate is also a GABA analog and possess neuroprotection, anticonvulsion and antihypertension effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Homotaurine; 3-Amino-1-propanesulfonic acid. CAS No. 3687-18-1. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g; 5 g. Product ID: HY-14602. | |
| Tranexamic acid | Tranexamic acid (cyclocapron), a cyclic analog of lysine, is an orally active antifibrinolytic agent. Tranexamic acid attenuates the effects of severe trauma, inhibits urokinase plasminogen activator and ameliorates dry wrinkles. Tranexamic acid can used for the research of hemostasis. Tranexamic acid is a PROTAC linker. Tranexamic acid is used to synthesize PROTACs (e.g. LZ-07 (HY-172590))[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: cyclocapron. CAS No. 1197-18-8. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 5 g; 10 g. Product ID: HY-B0149. | |
| Tranexamic acid-d2-1 | Tranexamic acid-d2-1 is the deuterium labeled Tranexamic acid[1]. Tranexamic acid (Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM[2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2714435-89-7. Pack Sizes: 500 μg; 1 mg. Product ID: HY-B0149S1. | |
| Tranexamic acid (Standard) | Tranexamic acid (Standard) is the analytical standard of Tranexamic acid. This product is intended for research and analytical applications. Tranexamic acid (cyclocapron), a cyclic analog of lysine, is an orally active antifibrinolytic agent. Tranexamic acid attenuates the effects of severe trauma, inhibits urokinase plasminogen activator and ameliorates dry wrinkles. Tranexamic acid can used for the research of hemostasis [1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: cyclocapron (Standard). CAS No. 1197-18-8. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B0149R. | |
| Tranilast | Tranilast (MK-341) acts as an anti-atopic agent. Tranilast suppresses production of prostaglandin D2 (PGD2, IC50= 0.1 mM). Tranilast sodium exhibits anti-inflammatory and immunomodulatory effects[1]. Tranilast sodium antagonizes angiotensin II and inhibits its biological effects in vascular smooth muscle cells[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-341; SB 252218. CAS No. 53902-12-8. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 50 mg; 100 mg. Product ID: HY-B0195. | |
| trans-1,4-Di(bromomethyl)cyclohexane | trans-1,4-Di(bromomethyl)cyclohexane is a drug intermediate for synthesis of various active compounds. Uses: Scientific research. Category: Signaling pathways. CAS No. 57702-84-8. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-47683. | |
| Trans-?2-?Hexenal (Standard) | Trans-2-Hexenal (Standard) is the analytical standard of Trans-2-Hexenal. This product is intended for research and analytical applications. Trans-2-Hexenal can be used for the determination of low-molecular-weight carbonyl compounds which are reactive with biological nucleophiles in biological samples[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E)-2-Hexenal (Standard). CAS No. 6728-26-3. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-128429R. | |
| trans-AUCB | trans-AUCB (t-AUCB) is a potent, orally active and selective soluble epoxide hydrolase (sEH) inhibitor with IC50s of 1.3 nM, 8 nM, 8 nM for hsEH, mouse sEH and rat sEH, respectively. trans-AUCB has anti-glioma activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: t-AUCB. CAS No. 885012-33-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-113974. | |
| trans-C75 | trans-C75 ((±)-C75) is an enantiomer of C75. C75 is a synthetic fatty-acid synthase (FASN) inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-C75. CAS No. 191282-48-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12364A. | |
| trans-Cinnamaldehyde | trans-Cinnamaldehyde can be used to prepare highly polyfunctionalized furan ring by reaction of alkyl isocyanides with dialkyl acetylenedicarboxylate[1]. trans-Cinnamaldehyde can be used to synthesize trans-cinnamaldehyde -β-cyclodextrin complex, an antimicrobial edible coating that increases the shelf life of fresh-cut fruits[2]. Uses: Scientific research. Category: Induced disease models products. CAS No. 14371-10-9. Pack Sizes: 1 g; 5 g. Product ID: HY-W019711. | |
| Trans-Cinnamic acid | trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Trans-3-Phenylacrylic acid. CAS No. 140-10-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-N0610. | |
| trans-Cyclohexane-1,2-diol | trans-Cyclohexane-1,2-diol (TCHD) is a transient dilator of the nuclear pore complex (NPC). By interacting with the hydrophobic core (FG nucleoporin) of the NPC, trans-Cyclohexane-1,2-diol can disrupt the NPC structure and reversibly increase the permeability of the nuclear pore, allowing macromolecules larger than 40 kDa (such as plasmid DNA) to enter the cell nucleus by passive diffusion, thereby enhancing the nuclear import efficiency of non-viral vectors. trans-Cyclohexane-1,2-diol can improve the efficiency of in vitro electrotransfection or lipid-mediated gene transfection, especially significantly increasing gene expression in differentiated airway epithelial cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1460-57-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W010514. | |
| Transfectam | Transfectam is a cationic lipid able to interact with DNA to form complexes that mediate efficient gene transfer into various eukaryotic cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 124050-77-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-143210. | |
| trans-Feruloyl-CoA | trans-Feruloyl-CoA (trans-Feruloyl-coenzyme A) is a derivative of coenzyme A. trans-Feruloyl-CoA also acts as an activated acyl donor involved in the synthesis of cell wall components such as lignin and feruloylated polysaccharides[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: trans-Feruloyl-coenzyme A. CAS No. 142185-30-6. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-CE02017. | |
| Transglutaminase, Streptoverticillium mobaraense | Transglutaminase, Streptoverticillium mobaraense (TG) is an enzyme that forms cross-links between protein molecules. Transglutaminase, Streptoverticillium mobaraense attaches proteins and peptides to small molecules, polymers, surfaces, DNA and other proteins. Transglutaminase, Streptoverticillium mobaraense is widely used in food applications in the meat, fish, dairy and baking industries[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TG. CAS No. 80146-85-6. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-P2962. | |
| Transketolase-IN-1 | Transketolase-IN-1 is a transketolase inhibitor and a herbicide. Transketolase-IN-1 inhibits weed growth and exhibits safety for maize and wheat at specified application rates. Transketolase-IN-1 can be used for the research of weed control in wheat and maize fields[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2763650-87-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-139731. | |
| Transketolase-IN-2 | Transketolase-IN-2 (compound 4w) is a potent Transketolase inhibitor. Transketolase-IN-2 shows strong inhibition of Digitaria sanguinalis and Amaranthus retroflexus (over 90% at 200 mg/L and about 80% at 100 mg/L). Transketolase-IN-2 can be used in studies of weed control[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2757552-21-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151600. | |
| Transketolase-IN-3 | Transketolase-IN-3 is a potent transketolase (TK) inhibitor. Transketolase-IN-3 has herbicidal activity and has inhibitory effects against Digitaria sanguinalis (DS) and Amaranthus retroflexus (AR). Transketolase-IN-3 can be used for the research of herbicides[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2757552-03-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151604. | |
| trans-Latanoprost | trans-Latanoprost (5,6-trans-Latanoprost) is the trans isomer of Latanoprost (HY-B0577). trans-Latanoprost is promising for research of glaucoma and high eye pressure[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (5E)-Latanoprost; 5,6-trans-Latanoprost. CAS No. 913258-34-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135163. | |
| trans-Ned 19 | trans-Ned 19 is a NAADP antagonist and TPC blocker. trans-Ned 19 suppresses the calcium signal and the rat aorta relaxation in response to low histamine concentrations. trans-Ned 19 increases the spontaneous acrosome reaction rate, alleviates anti-CD3 mAb-induced intestinal inflammation, and improves kidney damage in mice with nephrotoxic serum nephritis[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1354235-96-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-103316. | |
| (+)-trans-Permethrin | (+)-trans-Permethrin ((+)-trans-NRDC-143) is a pyrethroid which is synthetic derivative of the natural toxins pyrethrins contained in the flowers of Chrysanthemum species[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-trans-NRDC-143; (1R)-trans-Permethrin. CAS No. 51877-74-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-B0887A. | |
| trans-Platinum(II)diammine dichloride | trans-Platinum(II)diammine dichloride (trans-platinumdiamminedichloride) is a geometric isomer of Cisplatin (HY-17394). Trans-Platinum(II)diammine dichloride is a DNA cross-linking agent that induces significant DNA cross-link damage while exhibiting low cytotoxicity. Trans-Platinum(II)diammine dichloride is useful for studying DNA-protein cross-links[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: trans-platinumdiamminedichloride. CAS No. 14913-33-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W075885. | |
| Transportan | Transportan is an amphipathic cell-penetrating peptide containing 12 functional amino acids from the amino terminus of the neuropeptide galanin and mastoparan in the carboxyl terminus, connected via a lysine. Transportan interacts with galanin receptors and G-proteins, modulates GTPase activity, enters cells via direct translocation and endocytic pathways, accumulates in cytoplasmic, nuclear, and membranous structures, and delivers cargo including peptides, PNAs, proteins, siRNA, and liposomes[1][2][3][4][5][6][7][8][9][10][11][12]. Uses: Scientific research. Category: Peptides. CAS No. 203716-10-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1732. | |
| trans-R-138727 | Trans-R-138727 is the trans isomer of R-138727 (HY-123669). R-138727 is the active metabolite of the antiplatelet agent Prasugrel (HY-15284). R-138727 is an irreversible inhibitor for the platelet receptor P2Y12, and inhibits ADP-induced platelet activation and aggregation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 239466-74-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-123669A. | |
| trans-Sulfo-SMCC | trans-Sulfo-SMCC is a non-cleavable and membrane permeable ADC crosslinker. Uses: Scientific research. Category: Signaling pathways. CAS No. 1286837-77-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126503. | |
| trans-Urocanic acid | trans-urocanic acid (trans-UCA), a natural epidermal constituent, inhibits human natural killer cell (NK) activity in vitro. trans-urocanic acid is active in regulating an immune function[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E)-Urocanic acid; trans-UCA. CAS No. 3465-72-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-113008B. | |
| trans-Vaccenic acid | trans-Vaccenic acid is a naturally occurring trans fatty acid (TFA). trans-Vaccenic acid inhibits nasopharyngeal carcinoma (NPC) cell growth and induces apoptosis through the inhibition of Bad/Akt phosphorylation. trans-Vaccenic acid is a precursor for the synthesis of saturated fatty acid in the rumen and of conjugated Linoleic acid (CLA) at the tissue level. trans-Vaccenic acid exerts hypolipidemic effects in a rat model of obesity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 693-72-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-113427. | |
| trans-Zeatin | trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation. Uses: Scientific research. Category: Signaling pathways. CAS No. 1637-39-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-19700. | |
| trans-Zeatinriboside | trans-Zeatinriboside is a zeatin-type cytokinin and plant growth regulator. trans-Zeatinriboside is produced by the terrestrial filamentous cyanobacterium Nostoc sp. HK-01 and Agrobacterium tumefaciens (including Ti plasmid-dependent and Ti plasmid-independent strains). trans-Zeatinriboside is detectable as a cytokinin component in growing crown galls, and accumulates in large amounts in CHRK1-silenced transgenic tobacco accompanied by pleiotropic developmental abnormalities. trans-Zeatinriboside can be used in studies related to crown galls[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6025-53-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W011151. | |
| trans-Zeatinriboside (Standard) | trans-Zeatinriboside is a type of cytokinin precursor, acts as a major long-distance signalling form in xylem vessels, regulates leaf size and meristem activity-related traits. Uses: Scientific research. Category: Signaling pathways. CAS No. 6025-53-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011151R. | |
| TR antagonist 1 | TR antagonist 1 is a high-affinity thyroid hormone receptor (TR) antagonist with IC50s of 36 and 22 nM for TRα and TRβ, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 500794-88-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111443. | |
| Tranylcypromine hemisulfate | Tranylcypromine (SKF 385) hemisulfate is an irreversible, nonselective monoamine oxidase (MAO) inhibitor used in the treatment of depression. Tranylcypromine hemisulfate is also a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis. Tranylcypromine has antidepressant effects[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SKF 385 hemisulfate. CAS No. 13492-01-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-B1496. | |
| Tranylcypromine hydrochloride | Tranylcypromine hydrochloride (SKF 385 hydrochloride) is an irreversible inhibitor of lysine-specific demethylase 1 (LSD1/BHC110) and monoamine oxidase (MAO). Tranylcypromine hydrochloride inhibits LSD1, MAO A and MAO B with IC50s of 20.7, 2.3 and 0.95 μM, respectively. Tranylcypromine hydrochloride can be used for the research of depression[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SKF 385 hydrochloride. CAS No. 1986-47-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-17447A. | |
| TRAP-1 | TRAP-1 (XJZ-06-462) is a non-covalent regulated induced proximity targeting chimera (RIPTAC) with JQ-1 carboxylic acid (HY-78695) as its target protein ligand. TRAP-1 forms a ternary complex with p53Y220C and BRD4, potently activates p53 transcription, and inhibits the growth and proliferation of tumor cells. TRAP-1 upregulates p21 and other p53 target genes in pancreatic cell lines carrying p53Y220C, and induces cellular senescence and apoptosis. TRAP-1 can be used in cancer research involving p53Y220C-carrying tumors[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XJZ-06-462. CAS No. 3109600-48-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-169369. | |
| TRAP1-IN-1 | TRAP1-IN-1 (compound 35) is a potent and selective inhibitor of TRAP1, a mitochondrial isoform of Hsp90. TRAP1-IN-1 has >250-fold TRAP1 selectivity over Grp94, and disrupts TRAP1 tetramer stability, induces TRAP1 client protein degradation. TRAP1-IN-1 also inhibits mitochondrial complex I of oxidative phosphorylation OXPHOS, disrupts the mitochondrial membrane potential, and enhances glycolysis metabolism[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3031102-94-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155063. | |
| TRAP-6 | TRAP-6 (PAR-1 agonist peptide), a peptide fragment, is a selective protease activating receptor 1 (PAR1) agonist. TRAP-6 activates human platelets via the thrombin receptor. TRAP-6 shows no activity at PAR4[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PAR-1 agonist peptide; Thrombin Receptor Activator Peptide 6. CAS No. 141136-83-6. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0078. | |
| Trastuzumab | Trastuzumab is a humanized IgG1 monoclonal antibody that selectively binds to HER2 with high affinity. Trastuzumab can be used for the research of HER2-positive metastatic breast cancer and gastric cancer[1][2][3]. (Note: The product specifications below only indicate the effective content of Trastuzumab. The component ratio of this product is Trastuzumab : excipients = 1:0.6-1:0.9.). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anti-Human HER2, Humanized Antibody. CAS No. 180288-69-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P9907. | |
| Trastuzumab (anti-HER2) | Trastuzumab (anti-HER2) is a humanized IgG1 monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab (anti-HER2) has the potential for HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastric Cancer research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anti-Human HER2, Humanized Antibody (anti-HER2). CAS No. 180288-69-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P9907A. | |
| Trastuzumab deruxtecan | Trastuzumab deruxtecan (DS-8201a) is an anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate (ADC). Trastuzumab deruxtecan is composed of a humanized anti-HER2 antibody, an enzymatically cleavable peptide-linker, a topoisomerase I inhibitor (a toxin component of Dxd), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E). Trastuzumab deruxtecan can be used for the research of HER2-positive breast cancer and gastric cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: T-DXd; DS-8201; DS-8201a. CAS No. 1826843-81-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-138298A. | |
| Trastuzumab deruxtecan (solution) | Trastuzumab deruxtecan (T-DXd; DS-8201a) (solution) is an anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate (ADC). Trastuzumab deruxtecan is composed of a humanized anti-HER2 antibody, an enzymatically cleavable peptide-linker, a topoisomerase I inhibitor (a toxin component of Dxd), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E). Trastuzumab deruxtecan can be used for the research of HER2-positive breast cancer and gastric cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: T-DXd (solution); DS-8201 (solution); DS-8201a (solution). CAS No. 1826843-81-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-138298. | |
| Trastuzumab duocarmazine | Trastuzumab duocarmazine ((vic)-Trastuzumab duocarmazine) is a HER2-targeting ADC that is recognized and cleaved by histone B in tumor cells and selectively targets tumor cells. Trastuzumab duocarmazine has anti-tumor activity and can be used in cancer research related to uterine and ovarian sarcomas[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (vic)-Trastuzumab duocarmazine. CAS No. 1642152-40-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99547. | |
| Trastuzumab emtansine | Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that incorporates the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1 (HY-19792). Trastuzumab emtansine can be used for the research of advanced breast cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ado-Trastuzumab emtansine; PRO132365; T-DM 1. CAS No. 1018448-65-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P9921. | |
| Trastuzumab emtansine (solution) | Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that incorporates the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1 (derivative of maytansine), and the drug-linker conjugate for ADC is SMCC-DM1 (HY-101070). Trastuzumab emtansine can be used for the research of advanced breast cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ado-Trastuzumab emtansine (solution); PRO132365 (solution); T-DM 1 (solution). CAS No. 1018448-65-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P9921A. | |
| Travoprost | Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Fluprostenol isopropyl ester; AL6221; Flu-Ipr. CAS No. 157283-68-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0584. | |
| Traxoprodil | Traxoprodil (CP101,606) is a potent and selective NMDA antagonist and protect hippocampal neurons with an IC50 of 10 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP101,606. CAS No. 134234-12-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W018061. | |
| Trazodone | Trazodone (AF-1161 free base) is a triazolopyridine derivative that belongs to the class of serotonin receptor antagonists and reuptake inhibitors (SARIs). Trazodone has anti-depressant and anti-insomnious activity. Trazodone exerts antagonistic properties against a1- and a2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AF-1161 free base. CAS No. 19794-93-5. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-B0478A. | |
| Trazodone-d6 hydrochloride | Trazodone-d6 (hydrochloride) is the deuterium labeled Trazodone hydrochloride[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AF-1161-d6. CAS No. 1181578-71-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0478AS. | |
| TRC051384 | TRC051384 is a potent inducer of heat shock protein 70 (HSP70). TRC051384 exhibits protective effects against neuronal trauma via inhibition of necroptosis. TRC051384 can be used for the research of ischemic stroke[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 867164-40-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101712. | |
| Trebananib | Trebananib (2xCon4C) is an Fc fusion peptibody. Trebananib exerts its effects by blocking the binding of angiopoietin 1 (Ang1) and angiopoietin 2 (Ang2) to the TIE2 receptor. Trebananib has anti-angiogenic and anti-tumor activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2xCon4C; AMG 386. CAS No. 894356-79-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99546. | |
| Tregalizumab | Tregalizumab is a humanized anti-human CD4 monoclonal antibody (IgG1 type) that selectively activates the suppressive properties of regulatory T cells (Tregs) in vitro. Tregalizumab can be used in the research of autoimmune diseases (resulting from insufficient Treg activity) and allergies[1][2][3]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: BT-061. CAS No. 1207446-68-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99327. | |
| Trehalose-6,6'-dibehenate | Trehalose-6,6'-dibehenate is an orally active glycolipid. Trehalose-6,6'-dibehenate activates Mincle and inflammasome, inducing IL-1β secretion in a caspase activity-dependent manner. Trehalose-6,6'-dibehenate exerts a Myd88-dependent adjuvant activity. Trehalose-6,6'-dibehenate induces Th-1/Th-17 immune responses[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 66758-35-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-112137. | |
| Trehalose 6,6-dimycolate | Trehalose 6,6'-dimycolate (Cord Factor) is trehalose 6,6'-dimycolate, a cell wall glycolipid of Mycobacterium tuberculosis, which can be used to simulate inflammation and granuloma induced by Mycobacterium tuberculosis (MTB) form. Trehalose 6,6-dimycolate also protects Mycobacterium tuberculosis from macrophage-mediated killing, inhibits efficient antigen presentation, and reduces the development of protective T cell responses[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cord Factor. CAS No. 61512-20-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W145657. | |
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