MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| α,β-Methylene-ATP trisodium | α,β-Methylene-ATP trisodium is an agonist of P2X1 and P2X3 receptors and can cross the blood-brain barrier. α,β-Methylene-ATP trisodium can trigger a reflex pressor response by activating P2X receptors in peripheral muscles and the central locus coeruleus (LC); this effect can be blocked by the P2X antagonist PPADS (HY-108960). α,β-Methylene-ATP trisodium also activates noradrenergic neurons in the central locus coeruleus, mediating antinociceptive effects; this effect can be attenuated by the locus coeruleus damaging agent DSP-4 (HY-103210/HY-121602). α,β-Methylene-ATP trisodium can be used to study the pathological mechanisms of neuropathic pain, cardiovascular reflex regulation, and antinociceptive effects of the central nervous system[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1343364-54-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-108652. |  |
| alpha-Boswellic acid | alpha-Boswellic acid (α-Boswellic acid) is an orally active pentacyclic triterpenoid compound that can be extracted from frankincense. alpha-Boswellic acid has anti-inflammatory and antitumor activities. alpha-Boswellic acid can be used in Alzheimer's disease (AD) research[1][2][3]. Uses: Scientific research. Category: Natural products. Alternative Names: α-Boswellic acid. CAS No. 471-66-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N0611. | |
| α-Bungarotoxin | α-Bungarotoxin is a competitive antagonist at nicotinic acetylcholine receptors (nAChRs). α-Bungarotoxin, a selective α7 receptor blocker, blocks α7 currents with an IC50 of 1.6 nM and has no effects on α3β4 currents at concentrations up to 3 μM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 11032-79-4. Pack Sizes: 500 μg; 1 mg. Product ID: HY-P1264. | |
| α-Carotene | α-Carotene, a precursor of vitamin A, is used as an anti-metastatic agent or as an adjuvant for anti-cancer agents. α-Carotene is isolated from yellow-orange and dark-green vegetables[1][2]. Uses: Scientific research. Category: Natural products. CAS No. 7488-99-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-113462. | |
| α-Casozepine | α-Casozepine is an orally effective anxiolytic that binds to the benzodiazepine site of the GABAA receptor in bovine samples with an IC50 of 88 μM. α-Casozepine exerts anxiolytic and anti-stress effects on cats exposed to unfamiliar environments and dogs undergoing road transport. α-Casozepine exhibits significant anxiolytic activity in rats. α-Casozepine can be used in studies related to fear, anxiety and stress[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 117592-45-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P2602. | |
| α-CGRP (human) | α-CGRP (human) (Calcitonin gene-related peptide) is a regulatory neuropeptide of 37 amino acids. α-CGRP (human) is widely distributed in the central and peripheral nervous system. α-CGRP (human) is a potent vasodilator and has inotropic and chronotropic effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Calcitonin gene-related peptide. CAS No. 90954-53-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1071. | |
| α-CGRP (mouse, rat) | α-CGRP (mouse, rat), a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP (mouse, rat) can lead to a fall in blood pressure and an increase in heart rate by peripheral administration, also relax colonie smooth muscle. α-CGRP (mouse, rat) has the potential in cardiovascular, pro-inflammatory, migraine and metabolic studies[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CGRP (83-119), mouse, rat. CAS No. 83651-90-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P0203. | |
| α-Cyclodextrin | α-Cyclodextrin (α-CD) is a soluble fiber derived from corn. α-Cyclodextrin can deplete sphingolipids and phospholipids from cell membranes. α-Cyclodextrin interacts with tubulin. α-Cyclodextrin improves defenses against SARS-CoV-2 infection. α-Cyclodextrin enhances the anticancer efficacy of Crcumin (HY-N0005) against breast, lung and cervical cancer. α-Cyclodextrin has beneficial effects on body weight and blood lipids[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10016-20-3. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B1513. | |
| alpha-Cyperone (Standard) | alpha-Cyperone (Standard) is the analytical standard of alpha-Cyperone. This product is intended for research and analytical applications. alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD. Uses: Scientific research. Category: Signaling pathways. Alternative Names: α-Cyperone (Standard); (+)-α-Cyperone (Standard). CAS No. 473-08-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0710R. | |
| α-Demethylnaproxen | α-Demethylnaproxen is the major metabolite of Nabumetone (HY-B0559), Nabumetone is an orally active COX-2 inhibitor with anti-inflammatory activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 23981-47-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-W086896. | |
| α-D-Galactose pentaacetate | α-D-Galactose pentaacetate (Pentaacetyl-α-D-galactopyranose) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pentaacetyl-α-D-galactopyranose. CAS No. 4163-59-1. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g; 50 g; 100 g; 500 g. Product ID: HY-W106550. | |
| Alphadolone acetate | Alphadolone acetate (Alfadolone acetate) is a steroid agent that can suppress or relieve pain, with antinociception[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Alfadolone acetate; GR 2/1574. CAS No. 23930-37-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-108068. | |
| α-Eleostearic acid | α-Eleostearic acid (cis-Eleostearic acid), a conjugated linolenic acid, is an apoptosis inducer. α-Eleostearic acid is also a ferroptosis inducer. α-Eleostearic acid exhibits antioxidant and antitumor activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: cis-Eleostearic acid. CAS No. 506-23-0. Pack Sizes: 1 mg (35.92 mM * 100 μL in Methanol). Product ID: HY-27787. | |
| Alpha-Estradiol | Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Alfatradiol; Epiestradiol; Epiestrol. CAS No. 57-91-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0141A. | |
| α-ethyl 2C-D hydrochloride | α-ethyl 2C-D (BL-3912) hydrochloride is a phenethylamine and amphetamine compound. In drug discrimination studies, α-ethyl 2C-D hydrochloride can serve as a reference standard for MDMA [1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BL-3912; alpha-EH DOM. CAS No. 54690-19-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W725213. | |
| α-Factor Mating Pheromone, yeast | α-Factor Mating Pheromone, yeast is a tridecapeptide secreted by S. cerevisiae α cells via Ste2p receptor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mating Factor α. CAS No. 59401-28-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1482. | |
| α-Fluoromethylhistidine dihydrochloride | α-Fluoromethylhistidine dihydrochloride is an orally active histidine decarboxylase inhibitor. α-Fluoromethylhistidine dihydrochloride depletes histamine in enterochromaffin-like (ECL) cells, reduces the number and volume density of secretory vesicles in ECL cells, and does not affect histamine storage in mast cells. α-Fluoromethylhistidine dihydrochloride abolishes Omeprazole (HY-B0113)-induced vacuolization of ECL cells and decreases gastrin-induced histamine efflux from ECL cells. α-Fluoromethylhistidine dihydrochloride does not alter the granular characteristics of ECL cells, omeprazole-induced hypertrophy of ECL cells, gastrin-induced pancreastatin-like immunoreactivity efflux, nor does it affect gastric acid secretion induced by histamine or vagal stimulation. α-Fluoromethylhistidine dihydrochloride inhibits basal and gastrin-stimulated gastric acid secretion, reduces acid output induced by gastrin+IBMX (HY-12318), but does not directly affect acid generation in isolated parietal cells[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 81839-27-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-115822. | |
| α-Galactosidase, Aspergillus niger | α-Galactosidase, Aspergillus niger (EC 3.2.1.22), that is, α-galactosidase, is a glycoside hydrolase that widely exists in animals, plants and microorganisms, and is often used in biochemical research. α-Galactosidase catalyzes the hydrolysis of α-1,6-linked terminal galactose residues, including galactooligosaccharides, galactomannans, and galactolipids. Catalyzes many catabolic processes including cleavage of glycoproteins, glycolipids and polysaccharides[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EC 3.2.1.22. CAS No. 9025-35-8. Pack Sizes: 5 g; 10 g. Product ID: HY-P2871. | |
| α-Galactosylceramide | α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. α-Galactosylceramide is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide plus CD1d binds the NKT cell TCR (T cell antigen receptor)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: α-GalCer; KRN7000. CAS No. 158021-47-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-102022. | |
| α-Glucosidase, bacillus stearothermophilus | α-Glucosidase, bacillus stearothermophilus is a carbohydrase enzyme that catalyzes the release of α-glucose molecules. α-Glucosidase, bacillus stearothermophilus retains exoglycosidases, which hydrolyze α-glucosidic linkage at the nonreducing end of a substrate[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9001-42-7. Pack Sizes: 500 U; 1 KU. Product ID: HY-P2802A. | |
| α-Glucosidase, Yeast | α-Glucosidase, Yeast (α-D-Glucosidase, Yeast), a carbohydrate hydrolyzing enzyme, catalyzes the liberation of α-glucose from the non-reducing end of the substrate. α-Glucosidase can facilitate the absorption of glucose by the small intestine. Inhibition of α-Glucosidase is an effective management of non-insulin-dependent diabetes mellitus (NIDDM)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: α-D-Glucosidase, Yeast. CAS No. 9001-42-7. Pack Sizes: 100 U; 500 U. Product ID: HY-P2802. | |
| α-Glucosylrutin | α-Glucosylrutin, a flavonoid, is a potent antioxidant with free radical scavenging activity. α-Glucosylrutin reduces MMP-1 gene expression, protein expression, and enzyme activity, and reduces MMP-2 protein expression and enzyme activity in UVA-irradiated human dermal fibroblasts. α-Glucosylrutin prevents oxidative stress-induced intracellular tyrosine residue phosphorylation and counteracts intracellular thiol level depletion in human skin cells. α-Glucosylrutin is effective in the prevention of dermatologic diseases in which oxidative stress is of pathogenetic relevance, e.g. in polymorphous light eruption (PLE). α-Glucosylrutin can be used for the research of UV-induced skin photodamage/photoaging[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 130603-71-3. Pack Sizes: 10 mM * 1 mL in Water; 50 mg; 100 mg; 500 mg. Product ID: HY-164159. | |
| Alpha-Guanosine | Alpha-Guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 15398-66-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-154536. | |
| alpha-Hederin | alpha-Hederin (α-Hederin), a monodesmosidic triterpenoid saponin, exhibits promising antitumor potential against a variety of human cancer cell lines. alpha-Hederin could inhibit the proliferation and induce apoptosis of gastric cancer accompanied by glutathione decrement and reactive oxygen species generation via activating mitochondrial dependent pathway[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: α-Hederin. CAS No. 27013-91-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0255. | |
| α-Helical CRF(9-41) | α-Helical CRF(9-41) is a competitive CRF2 receptor antagonist with KB of ~100 nM. α-Helical CRF(9-41) is also a partial agonist of CRF1 receptor with an EC50 of 140 nM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 90880-23-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1294. | |
| α-Humulene | α-Humulene is a main constituent of Tanacetum vulgare L. (Asteraceae) essential oil with anti-inflammation (IC50=15±2 μg/mL). α-Humulene inhibits COX-2 and iNOS expression[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Humulene; α-Caryophyllene. CAS No. 6753-98-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-N6968. | |
| α-Hydroxyglutaric acid | α-Hydroxyglutaric acid (2-Hydroxyglutarate) is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Hydroxyglutarate; 2-Hydroxyglutaric acid; 2-Hydroxypentanedioic acid. CAS No. 2889-31-8. Pack Sizes: 5 mg (67.52 mM * 0.5mL in Ethanol); 10 mg (67.52 mM * 1mL in Ethanol); 25 mg (67.52 mM * 2.5mL in Ethanol). Product ID: HY-113038B. | |
| α-Hydroxyglutaric acid-13C5 disodium | α-Hydroxyglutaric acid-13C5 (sodium) is the 13C labeled α-Hydroxyglutaric acid sodium[1]. α-Hydroxyglutaric acid (2-Hydroxyglutarate) sodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid sodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Hydroxyglutarate-13C5 disodium; 2-Hydroxyglutaric acid-13C5 disodium; 2-Hydroxypentanedioic acid-13C5 disodium. CAS No. 2482467-23-0. Pack Sizes: 1 mg. Product ID: HY-113038AS. | |
| α-Hydroxyglutaric acid-d4 disodium | α-Hydroxyglutaric acid-d4 (disodium) is the deuterium labeled α-Hydroxyglutaric acid disodium[1]. α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Hydroxyglutarate-d4 disodium; 2-Hydroxyglutaric acid-d4 disodium; 2-Hydroxypentanedioic acid-d4 disodium. CAS No. 2483831-91-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113038AS1. | |
| α-Hydroxyglutaric acid disodium | α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Hydroxyglutarate disodium; 2-Hydroxyglutaric acid disodium; 2-Hydroxypentanedioic acid disodium. CAS No. 40951-21-1. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113038A. | |
| α-Ketoglutaric acid disodium dihydrate | α-Ketoglutaric acid disodium dihydrate, an important dicarboxylic acid, is an intermediate in the tricarboxylic acid cycle (TCC) and amino acid metabolism. α-Ketoglutaric acid disodium dihydrate can be used as building block chemical for the chemical synthesis of heterocycles, dietary supplement, component of infusion solutions and wound healing compounds, or as main component of new elastomers with a wide range of interesting mechanical and chemical properties[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1282616-74-3. Pack Sizes: 10 mM * 1 mL in Water; 10 g; 25 g; 50 g; 100 g; 500 g. Product ID: HY-W802699. | |
| α-Lactalbumin | α-Lactalbumin is a globular whey protein that exists in milk. α-Lactalbumin binds Ca2+, Mg2+, Mn2+, Na+, K+ and Zn2+ ions; among these, Ca2+ binding enhances protein stability, while Zn2+ binding reduces stability and induces aggregation. α-Lactalbumin forms amyloid fibrils, amorphous aggregates, nanoparticles and nanotubes depending on external conditions. α-Lactalbumin exhibits bactericidal and antiviral activities. α-Lactalbumin has anxiolytic and antidepressant activities, and its effects are enhanced under stress conditions[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9051-29-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-NP009. | |
| α-Linolenic acid | α-Linolenic acid (ALA (free base); C18:3 (9Z,12Z,15Z) (free base); C18:3 n-3 (free base)) is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALA free base; C18:3 (9Z,12Z,15Z) free base; C18:3 n-3 free base. CAS No. 463-40-1. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-N0728. | |
| α-Linolenic acid-13C18 | α-Linolenic acid-13C18 is the 13C labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 287111-28-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0728S3. | |
| α-Linolenic acid-d14 | α-Linolenic acid-d14 is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1622944-40-4. Pack Sizes: 100 μg (3.42 mM * 100 μL in Ethanol); 1 mg; 5 mg. Product ID: HY-N0728S2. | |
| α-Lipoic Acid | α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation[1][2][3]. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells[4]. α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Thioctic acid; (±)-α-Lipoic acid; DL-α-Lipoic acid. CAS No. 1077-28-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-N0492. | |
| α-Lipoic Acid-d5 | α-Lipoic Acid-d5 is the deuterium labeled α-Lipoic Acid. α-Lipoic Acid is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation[1][2][3]. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells[4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Thioctic acid-d5; (±)-α-Lipoic acid-d5; DL-α-Lipoic acid-d5. CAS No. 1189471-66-6. Pack Sizes: 5 mg. Product ID: HY-N0492S. | |
| α-Lipoic acid-NHS | α-Lipoic acid-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DL-α-Lipoic acid-NHS. CAS No. 40846-94-4. Pack Sizes: 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-141336. | |
| α-Lipoic Acid sodium | α-Lipoic Acid (Thioctic acid) sodium is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid sodium inhibits NF-κB-dependent HIV-1 LTR activation[1][2][3]. α-Lipoic Acid sodium induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells[4]. α-Lipoic Acid sodium can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Thioctic acid sodium; (±)-α-Lipoic acid sodium; DL-α-Lipoic acid sodium. CAS No. 2319-84-8. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-N0492A. | |
| alpha-Mangostin | alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: α-Mangostin. CAS No. 6147-11-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0328. | |
| α-Mannosidase | α-Mannosidase is a hydrolytic enzyme targeting mannose-containing glycoproteins or glycolipids. α-Mannosidase is promising for research of inherited α-mannosidosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9025-42-7. Pack Sizes: 1 mg. Product ID: HY-P2950. | |
| α-Methyl-DL-aspartic acid | α-Methyl-DL-aspartic acid is a specific inhibitor of argininosuccinate synthase (ASS), and also is the rate-limiting enzyme for the recycling of 1-citrulline to 1-arginine[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2792-66-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W142119. | |
| α-Methyl-p-tyrosine | α-Methyl-p-tyrosine is a competitive inhibitor of tyrosine hydroxylase, which converts tyrosine into DOPA. α-Methyl-p-tyrosine is also an orally active inhibitor of catecholamine synthesis, inhibiting the hydroxylation of tyrosine into DOPA. α-Methyl-p-tyrosine can be used in research related to epilepsy, glaucoma, cancer, and other related diseases[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 658-48-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-33549. | |
| α-MSH | α-MSH (α-Melanocyte-Stimulating Hormone), an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: α-Melanocyte-Stimulating Hormone. CAS No. 581-05-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0252. | |
| α-MSH (11-13) acetate | α-MSH (11-13) (ACTH-(11-13)) acetate is a C-terminal tripeptide of α-MSH that can cross the blood-brain barrier. α-MSH (11-13) acetate exhibits antipyretic, anti-inflammatory, and antibacterial activities. α-MSH (11-13) acetate also exerts neuroprotective effects after traumatic brain injury by inhibiting excessive activation of microglia and reducing neuronal apoptosis. α-MSH (11-13) acetate can be used in research related to traumatic brain injury, fever, and bacterial infections[1][2][3]. Uses: Scientific research. Category: Peptides. Alternative Names: ACTH-(11-13) acetate; Lys-Pro-Val acetate; H-Lys-Pro-Val-OH acetate. CAS No. 2828433-34-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129724A. | |
| α-MSH TFA | α-MSH (α-Melanocyte-Stimulating Hormone) TFA, an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH TFA is a post-translational derivative of pro-opiomelanocortin (POMC)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: α-Melanocyte-Stimulating Hormone TFA. CAS No. 171869-93-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0252A. | |
| α-Muricholic acid | α-Muricholic acid is the most abundant primary bile acid in rodents[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2393-58-0. Pack Sizes: 1 mg. Product ID: HY-115433. | |
| α-NAD | α-NAD (α-Nicotinamide Adenine Dinucleotide) serves as a substrate for reninase, functions as an analog of β-NAD, affects the kinetics of NAD-dependent enzymes, and also plays a critical role as a cofactor in mitochondrial redox reactions[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: α-Nicotinamide Adenine Dinucleotide. CAS No. 7298-93-3. Pack Sizes: 5 mg. Product ID: HY-B0445B. | |
| Alpha-Naphthoflavone | Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. IC 50 and K I value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 604-59-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125833. | |
| Alpha-Naphthoflavone (Standard) | Alpha-Naphthoflavone (Standard) is the analytical standard of Alpha-Naphthoflavone. This product is intended for research and analytical applications. Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. IC 50 and K I value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 604-59-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125833R. | |
| α-Naphtholbenzein | α-Naphtholbenzein (p-Naphtolbenzein) is a dye. α-Naphtholbenzein can be used as a pH indicator. α-Naphtholbenzein is commonly used in experiments such as acid-base neutralization reactions, titration, and pH measurement[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: p-Naphtolbenzein. CAS No. 145-50-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-125457. | |
| α-NETA | α-NETA is a potent and noncompetitive choline acetyltransferase (ChA) inhibitor with an IC50 of 9 μM. α-NETA is a potent ALDH1A1 (IC50=0.04 μM) and chemokine-like receptor-1 (CMKLR1) antagonist. α-NETA weakly inhibits cholinesterase (ChE; IC50=84 μM) and acetylcholinesterase (AChE; IC50=300 μM). α-NETA has anti-cancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 115066-04-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138097. | |
| α-Phellandrene | α-Phellandrene (alpha-Phellandrene) is an orally active monoterpenoid and insecticide. α-Phellandrene can be isolated from plant essential oils. α-Phellandrene induces Apoptosis and Autophagy. α-Phellandrene promotes cAMP signaling pathway and increases NO production. α-Phellandrene has anti-inflammatory and anticancer (sarcoma) activities. α-Phellandrene shows insecticidal activity against Lucilia cuprina L3. α-Phellandrene reduces mechanical hyperalgesia[1][2][3][4][5][6][7][8][9][10][11]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: alpha-Phellandrene. CAS No. 99-83-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g. Product ID: HY-121615. | |
| (αR)-Cyclopropaneacetamide-Exatecan | (αR)-Cyclopropaneacetamide-Exatecan (SHR169265) is a DNA Topoisomerase I inhibitor with enhanced membrane permeability (with an IC50 of 1.34 μM against the human DNA Topoisomerase I). (αR)-Cyclopropaneacetamide-Exatecan exerts cytotoxic effects by inhibiting the enzymatic activity of Topoisomerase I, and this anticancer effect is independent of the expression level of HER2. (αR)-Cyclopropaneacetamide-Exatecan is an ADC Cytotoxin derived from Exatecan (HY-13631), which can be used in research related to advanced cancers such as breast cancer, gastric cancer, colorectal cancer and non-small cell lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SHR169265. CAS No. 2414254-37-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156617A. | |
| α-Rhamnosidase | α-Rhamnosidase is a glycoside hydrolase. α-Rhamnosidase is able to finish the enzymatic de-glycosylation of many nature flavone glycosides[1]. Uses: Scientific research. Category: Enzymes. Alternative Names: α-L-Rhamnosidase. CAS No. 37288-35-0. Pack Sizes: 1 KU. Product ID: HY-E70104. | |
| α-Santalol | α-Santalol (cis-α-Santalol), a naturally occurring sesquiterpene, is an orally active anticancer agent and apoptosis inducer. α-Santalol activates caspase-3 to drive apoptotic processes. >α-Santalol induces apoptosis, decreases cell viability, and causes PARP cleavage in human prostate cancer cells. α-santalol inhibits Akt/Survivin pathway to induce cell death. α-Santalol can be used for the research of prostate cancer and diabetes mellitus[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: cis-α-Santalol. CAS No. 115-71-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N11908. | |
| α-Solanine | α-solanine, a bioactive component and one of the major steroidal glycoalkaloids in Solanum nigrum, has been observed to inhibit growth and induce apoptosis in cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 20562-02-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N6602. | |
| α-Synuclein 4554W | α-Synuclein 4554W is an inhibitor of α-Synuclein (aSyn) aggregation with associated toxicity. α-Synuclein 4554W consists of GIVNGVKA sequences, previously identified through intracellular library screening. α-Synuclein 4554W reduces fibril formation of aSyn mutants assocaited with Parkinsons disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2243207-00-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5082. | |
| α-Synuclein aggregate binder 1 | α-Synuclein aggregate binder 1 (Compound C05-05) is a specific binder for α-synuclein aggregates and can inhibit α-synuclein aggregation. α-Synuclein aggregate binder 1 can be used as a fluorescent probe (excitation wavelength 900 nm, detection wavelength 500-550 nm) for optical imaging, and can also inhibit α-synuclein fibril formation by blocking the aggregation process. α-Synuclein aggregate binder 1 can be used for positron emission tomography (PET) imaging after being labeled with 18F. α-Synuclein aggregate binder 1 can be used for visual diagnosis of brain lesions and mechanism research of neurodegenerative diseases such as Parkinson's disease and Lewy body dementia[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1565797-17-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160116. | |
| (±)-α-Tocopherol acetate | (±)-α-Tocopherol acetate ((±)-Vitamin E acetate), is a orally active synthetic form of vitamin E. (±)-α-Tocopherol acetate is the ester of acetic acid and α-tocopherol. (±)-α-Tocopherol acetate can be used for the research of the susceptibility of farmed fish to infectious diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Vitamin E acetate. CAS No. 7695-91-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-B1278B. | |
| (±)-α-Tocopherol acetate (Standard) | (±)-α-Tocopherol acetate (Standard) is the analytical standard of (±)-α-Tocopherol acetate. This product is intended for research and analytical applications. (±)-α-Tocopherol acetate ((±)-Vitamin E acetate), is a orally active synthetic form of vitamin E. (±)-α-Tocopherol acetate is the ester of acetic acid and α-tocopherol. (±)-α-Tocopherol acetate can be used for the research of the susceptibility of farmed fish to infectious diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Vitamin E acetate (Standard). CAS No. 7695-91-2. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B1278BR. | |
| α-Tocopherol-d6 acetate | α-Tocopherol-d6 (acetate) is the deuterium labeled D-α-Tocopherol acetate. D-α-Tocopherol acetate (D-Vitamin E acetate) can be hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 143731-16-2. Pack Sizes: 1 mg. Product ID: HY-B1278S1. | |
| α-Tocopherol phosphate | α-Tocopherol phosphate is an antioxidant that protects against long-wave UVA1 induced cell death and scavenge UVA1 induced ROS in a skin cell model. α-Tocopherol phosphate exhibits angiogenesis-promoting activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: alpha-Tocopherol phosphate; TocP; vitamin E phosphate. CAS No. 38976-17-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16686. | |
| α-Tocotrienol | α-Tocotrienol is an isoform of vitamin E and found in vegetables, fruits, seeds, nuts, grains, and oils. Vitamin E plays a role as an antioxidant, in lowering cholesterol and other lipids, as a neuroprotective and anticancer agent, and in cardiovascular disease protection. Uses: Scientific research. Category: Signaling pathways. CAS No. 58864-81-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129459. | |
| αvβ1 integrin-IN-1 | αvβ1 integrin-IN-1 (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1689540-62-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100445. | |
| αvβ5 integrin-IN-1 | αvβ5 integrin-IN-1 (Compound 12) is a selective αvβ5 inhibitor (pIC50 = 8.2). αvβ5 integrin-IN-1 exhibits 800-fold selectivity for αvβ5 versus αvβ3[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2615912-33-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145363. | |
| αVβ8-IN-1 | αVβ8-IN-1 is a αVβ8 integrin inhibitor. αVβ8-IN-1 has been shown to inhibit the growth of tumors such as EMT6, CT26, KPC, and TKCC-10. αVβ8-IN-1 can be used in research related to idiopathic pulmonary fibrosis (IPF), non-specific interstitial pneumonia (NSIP), and tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3048440-55-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-164360. | |
| α-Viniferin | α-Viniferin is an anti-inflammatory compound from Caragana chamlagu root[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-α-Viniferin. CAS No. 62218-13-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2854. | |
| α-Vitamin E | α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-α-Tocopherol; D-α-Tocopherol. CAS No. 59-02-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 1 g; 5 g; 10 g; 25 g; 50 g. Product ID: HY-N0683. | |
| α-Vitamin E-d6 | α-Vitamin E-d6 is the deuterium labeled α-Vitamin E[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-α-Tocopherol-d6; D-α-Tocopherol-d6. CAS No. 113892-08-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7148S. | |
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