MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Amodiaquine | Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Amodiaquin. CAS No. 86-42-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1322A. |  |
| Amodiaquine dihydrochloride | Amodiaquine dihydrochloride (Amodiaquin dihydrochloride), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor with a Ki of 18.6 nM. Amodiaquine dihydrochloride is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Amodiaquin dihydrochloride. CAS No. 69-44-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-B1322B. | |
| Amodiaquine dihydrochloride dihydrate | Amodiaquine dihydrochloride dihydrate (Amodiaquin dihydrochloride dihydrate), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine dihydrochloride dihydrate is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Amodiaquin dihydrochloride dihydrate. CAS No. 6398-98-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-B1322. | |
| Amonafide | Amonafide is a topoisomerase II inhibitor and DNA intercalator that induces apoptotic signaling by blocking the binding of Topo II to DNA. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AS1413. CAS No. 69408-81-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10982. | |
| Amotosalen hydrochloride | Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens. Light-activated Amotosalen binds and permanently crosslinks DNA, preventing replication and thus stopping proliferation of donor T cells. Amotosalen can be used for the study of blood system pathogen reduction technology and graft-versus-host disease (GVHD)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S-59. CAS No. 161262-45-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107004A. | |
| Amoxapine | Amoxapine (CL-67772) is a norepinephrine reuptake blocker and a 5-HT2/5-HT3 antagonist. Amoxapine can be used for the research of depression. Amoxapine has antibacterial activity. Amoxapine can enhance the killing effect of macrophages on mycobacterium by inducing autophagy, while protecting the cells from death[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CL-67772. CAS No. 14028-44-5. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 500 mg. Product ID: HY-B0991. | |
| Amoxicillin | Amoxicillin (Amoxycillin) is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Amoxycillin. CAS No. 26787-78-0. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-B0467A. | |
| Amoxicillin-clavulanate potassium | Amoxicillin-clavulanate potassium is an antibiotic. Amoxicillin-clavulanate potassium has the potential for the research of various bacterial infection[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 74469-00-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135532. | |
| Amoxicillin-d4 | Amoxicillin-d4 is a deuterium labeled Amoxicillin. Amoxicillin is an antibiotic with good oral absorption and broad spectrum antimicrobial activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Amoxycillin d4. CAS No. 2673270-36-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0467S. | |
| Amoxicillin sodium | Amoxicillin (Amoxycillin) sodium is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin sodium inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Amoxycillin sodium. CAS No. 34642-77-8. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0467. | |
| Amoxicillin trihydrate | Amoxicillin (Amoxycillin) trihydrateis an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin trihydrateis inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Amoxycillin trihydrate. CAS No. 61336-70-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0467B. | |
| AMPA-IN-3 | AMPA-IN-3 is an AMPA receptor inhibitor. AMPA-IN-3 inhibits TARP J2-dependent AMPA receptor activity with a pIC50 value of 10.7. A AMPA-IN-3 can be used for the research of neurological disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2034182-75-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-175443. | |
| AMPA receptor modulator-10 | AMPA receptor modulator-10 (Compound 9a) is an orally active AMPA receptor (AMPAR) positive allosteric modulator. AMPA receptor modulator-10 exhibits potent activity (pEC50 = 5.0) on the GluA2 subtype of AMPAR, significantly enhancing glutamate-induced calcium influx and current responses. AMPA receptor modulator-10 can reverse the memory impairment induced by Scopolamine (HY-N0296) and enhance cognitive function. AMPA receptor modulator-10 can be used for the research of neurological disease, such as schizophrenia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 620940-01-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-177873. | |
| AMPC | AMPC is a potent and effective TFF3 inhibitor. AMPC inhibits cell proliferation, survival, oncogenicity, and CSC-like behaviour in TFF3-positive CMS4 CRC cells. AMPC acts as a potential anti-cancer agent alone or in combination with 5-FU, and can be used for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2254434-33-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139065. | |
| AMPD2 inhibitor 1 | AMPD2 inhibitor 1 is an adenosine monophosphate deaminase 2 (AMPD2) inhibitor, used in the research of sugar craving, salt craving, umami craving, and addictions including agent, tobacco, nicotine and alcohol addictions. Uses: Scientific research. Category: Signaling pathways. CAS No. 2139356-35-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103673. | |
| AMP-Deoxynojirimycin | AMP-Deoxynojirimycin (AMP-DNM) is a potent ceramide glucosyltransferase and GCase 2 inhibitor. AMP-Deoxynojirimycin also is a GlcCer biosynthesis inhibitor[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMP-DNM. CAS No. 216758-20-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114615. | |
| Amphotericin B | Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death. Uses: Scientific research. Category: Signaling pathways. CAS No. 1397-89-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-B0221. | |
| Ampicillin | Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-(-)-α-Aminobenzylpenicillin. CAS No. 69-53-4. Pack Sizes: 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-B0522. | |
| Ampicillin-d5 | Ampicillin-d5 is the deuterium labeled Ampicillin. Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1426173-65-0. Pack Sizes: 5 mg. Product ID: HY-B0522S. | |
| Ampicillin sodium | Ampicillin sodium (D-(-)-α-Aminobenzylpenicillin sodium salt) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-(-)-α-Aminobenzylpenicillin sodium salt. CAS No. 69-52-3. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0522A. | |
| AMPK activator 4 | AMPK activator 4 is a potent AMPK activator without inhibition of mitochondrial complex I. AMPK activator 4 selectively activates AMPK in the muscle tissues. AMPK activator 4 dose-dependently improves glucose tolerance in normal mice, and significantly lowers fasting blood glucose level and ameliorates insulin resistance in db/db diabetic mice. Anti-hyperglycemic effect[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2493239-46-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131334. | |
| AMPK-IN-3 | AMPK-IN-3 (compound 67) is a potent and selective AMPK inhibitor with IC50s of 60.7, 107 and 3820 nM for AMPK (α2), AMPK (α1) and KDR, respectively. AMPK-IN-3 inhibits AMPK does not affect cell viability or cause significant cytotoxicity in K562 cells. AMPK-IN-3 can be used in study of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2417674-27-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151361. | |
| AMPK-IN-4 | AMPK-IN-4 (compound 19) is a potent inhibitor of (AMPK(α1) and AMPK(α2) with IC50s of 393 nM and 141 nM, respectively. AMPK-IN-4 plays an important role in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 873077-70-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155943. | |
| Ampkinone | Ampkinone is an indirect AMP-activated protein kinase (AMPK) activator. Uses: Scientific research. Category: Signaling pathways. CAS No. 1233082-79-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg. Product ID: HY-12831. | |
| AMP-PCP disodium | AMP-PCP disodium is an ATP analogue and can bind to Hsp90 N-terminal domain with a Kd value of 3.8 μM. AMP-PCP disodium binding favors the formation of the active homodimer of Hsp90[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 7414-56-4. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg. Product ID: HY-106723A. | |
| AMP-PNP tetralithium | AMP-PNP (Adenylyl-imidodiphosphate) tetralithium is a non-hydrolyzable ATP analog. AMP-PNP tetralithium binds to ATP binding sites competely but is not hydrolyzed by enzymes, providing stable experimental conditions for studying ATP-dependent processes. AMP-PNP tetralithium can also be used to study enzyme activity, kinase regulation, DNA/RNA metabolism, ion channel function, and protein complex assembly[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenylyl-imidodiphosphate tetralithium. CAS No. 72957-42-7. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg. Product ID: HY-128933. | |
| Amprenavir | Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.09 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VX-478. CAS No. 161814-49-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17430. | |
| AMPTX-1 | AMPTX-1 is a selective, orally active, covalent reversible BRD9 molecular glue degrader with a DC50 of 0.05 nM. AMPTX-1 selectively recruits BRD9 to the E3 ligase DCAF16. AMPTX-1 forms a ternary complex with BRD9 and a reversible covalent adduct with Cys58 on the surface of DCAF16. AMPTX-1 mediates BRD9 degradation via the proteasome and Cullin RING E3 ligase pathways. AMPTX-1 can be used in the research of solid tumors and hematological malignancies[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3033019-04-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-172615. | |
| Ampyrone | Ampyrone (4-Aminophenazone; 4-Aminoantipyrine) is a reversible and low-damage optical clearing agent and non-selective COX inhibitor based on UV absorption properties. Ampyrone can improve the optical transmittance of mouse skin and other tissues. Ampyrone can induce tissue refractive index matching by enhancing UV absorption, reduce light scattering, and achieve tissue transparency in vivo. Ampyrone reduces the synthesis of prostaglandin PGE2, thereby exerting anti-inflammatory, analgesic and antipyretic effects. Ampyrone inhibits DNA damage, cell apoptosis and immune cell phagocytosis induced by Doxorubicin (HY-15142A) and Cisplatin (HY-17394), etc., and participates in the regulation of toxicity in tumor chemotherapy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Aminophenazone. CAS No. 83-07-8. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-B1398. | |
| Amrecibart | Amrecibart is an anti-coagulation factor 11 human IgG4 κ monoclonal antibody. Recommend Isotype Controls: Human IgG4 kappa, Isotype Control (HY-P99003)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: REGN-9933. CAS No. 3008610-20-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991117. | |
| Amredobresib | Amredobresib (BI894999) is an orally active BET inhibitor. Amredobresib inhibits the binding of BRD4-BD1 and BRD4-BD2 bromodomains to acetylated histones with IC50 values of 5 nM and 41 nM, respectively. Amredobresib exhibits anticancer activity against acute myeloid leukemia (AML) and NUT cancer[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BI894999. CAS No. 1610044-98-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145550. | |
| AMS-17 | AMS-17 is a potent NLRP3 inhibitor, inhibiting microglia activation in vitro and in vivo. AMS-17 also inhibits cytokines such as caspase-1, TNF-α, IL-1β and inducible nitric oxide synthase (iNOS) in N9 cells. AMS-17 can be used for researching inflammation-associated neurological disorders, such as vascular dementia (VaD)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3019885-78-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146765. | |
| Amsacrine | Amsacrine (m-AMSA; acridinyl anisidide) is an inhibitor of topoisomerase II, and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: m-AMSA; acridinyl anisidide. CAS No. 51264-14-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13551. | |
| Amsacrine hydrochloride | Amsacrine hydrochloride (m-AMSA hydrochloride; acridinyl anisidide hydrochloride) is an inhibitor of topoisomerase II, and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: m-AMSA hydrochloride; acridinyl anisidide hydrochloride. CAS No. 54301-15-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-13551A. | |
| AMTB hydrochloride | AMTB hydrochloride is a selective TRPM8 channel blocker. AMTB hydrochloride inhibits icilin-induced TRPM8 channel activation with a pIC50 of 6.23. AMTB hydrochloride can be used for the research of the overactive bladder and painful bladder syndrome. AMTB hydrochloride is a non-selective inhibitor of voltage-gated sodium channels (NaV)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 926023-82-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-100345. | |
| AMT-NHS | AMT-NHS is an RNA-protein crosslinker. AMT-NHS is composed of a psoralen derivative and an N-hydroxysuccinimide ester group which react with RNA bases and primary amines of protein, respectively. AMT-NHS can penetrate into living yeast cells and crosslink Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different crosslinking patterns and targets both single- and double-stranded regions of RNA. AMT-NHS can be used for capturing diverse RNA-protein interactions in cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2925268-86-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150014. | |
| Amustaline dihydrochloride | Amustaline (S-303) dihydrochloride, a nucleic acid-targeted alkylator, is an efficient pathogen inactivation agent for blood components containing red blood cells. Amustaline dihydrochloride has three components: an acridine anchor (an intercalator that targets nucleic acids non-covalently), an effector (a bis-alkylator group that reacts with nucleophiles), and a linker (a small flexible carbon chain containing a labile ester bond that hydrolyzes at neutral pH to yield non-reactive breakdown products)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S-303 dihydrochloride. CAS No. 210584-54-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106991A. | |
| AMXT-1501 | AMXT-1501 is a Bacterial agent and polyamine transport system inhibitor. AMXT-1501 targets membrane phospholipids and exhibits antibacterial activity against a variety of Gram-positive and Gram-negative multidrug-resistant bacteria. AMXT-1501 inhibits capsular biosynthesis in Streptococcus pneumoniae. AMXT-1501 targets ornithine decarboxylase and polyamines to inhibit the proliferation of neuroblastoma cells. AMXT-1501 in combination with DFMO (HY-B0744) induces Apoptosis in neuroblastoma cells. AMXT-1501 is applicable to research related to multidrug-resistant bacterial infections, pneumococcal infections, Streptococcus pneumoniae infections, and neuroblastoma[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 441022-64-6. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124617. | |
| AMXT-1501 tetrahydrochloride | AMXT-1501 tetrahydrochloride is a Bacterial agent and polyamine transport system inhibitor. AMXT-1501 tetrahydrochloride targets membrane phospholipids and exhibits antibacterial activity against a variety of Gram-positive and Gram-negative multidrug-resistant bacteria. AMXT-1501 tetrahydrochloride inhibits capsular biosynthesis in Streptococcus pneumoniae. AMXT-1501 tetrahydrochloride targets ornithine decarboxylase and polyamines to inhibit the proliferation of neuroblastoma cells. AMXT-1501 tetrahydrochloride in combination with DFMO (HY-B0744) induces Apoptosis in neuroblastoma cells. AMXT-1501 tetrahydrochloride is applicable to research related to multidrug-resistant bacterial infections, pneumococcal infections, Streptococcus pneumoniae infections, and neuroblastoma[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2444815-84-1. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124617A. | |
| AMY-101 | AMY-101 (Cp40), a peptidic inhibitor of the central complement component C3 (KD = 0.5 nM), inhibits naturally occurring periodontitis in non-human primates (NHPs). AMY-101 (Cp40) exhibits a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cp40. CAS No. 1427001-89-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1717. | |
| AMY-101 TFA | AMY-101 TFA (Cp40 TFA), a peptidic inhibitor of the central complement component C3 (KD = 0.5 nM), inhibits naturally occurring periodontitis in non-human primates (NHPs). AMY-101 (Cp40) exhibits a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cp40 TFA. CAS No. 1789738-04-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1717A. | |
| Amygdalin | Amygdalin is a plant glucoside isolated from the stones of rosaceous fruits, such as apricots, peaches, almond, cherries, and plums. Uses: Scientific research. Category: Natural products. CAS No. 29883-15-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg. Product ID: HY-N0190. | |
| Amylin (8-37), rat | Amylin (8-37), rat is a truncated analog of native Amylin that selectively inhibits insulin-related glucose uptake and glycogen deposition in muscle tissue. Amylin (8-37), rat is a weak amylin receptor (AMY) antagonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Amylin (8-37) (mouse, rat). CAS No. 138398-61-5. Pack Sizes: 500 μg; 5 mg. Product ID: HY-P1473. | |
| Amylin, amide, human | Amylin, amide, human, a 37-amino acid polypeptide, is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. Amylin, amide, human inhibits glucagon secretion, delays gastric emptying, and acts as a satiety agent[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DAP amide, human. CAS No. 122384-88-7. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P1070. | |
| Amylin, amide, rat | Amylin, amide, rat is a potent and high affinity ligand of Amylin receptor AMY1 and AMY3 receptors and variably of AMY2 receptors; binding studies are generally used for the latter receptor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Amylin (rat). CAS No. 124447-81-0. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P1464. | |
| AMZ30 | AMZ30 is selective protein phosphatase methylesterase-1(PME-1) inhibitor with IC50s of 600 nM and 3.5 μM in human cell lysates and in HEK 293T cells, respectively. AMZ30 shows >100-fold selectivity relative to other serine hydrolases. AMZ30 reduces the demethylated form of PP2A in living cells. AMZ30 attenuates muscle cell differentiation. AMZ30 increases the resistance of U87MG and U251MG glioblastoma cells to t-BHP-induced oxidative stress. AMZ30can be used for the study of glioblastoma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1313613-09-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-12833. | |
| AN11251 | AN11251 is a potent and oral active anti-Wolbachia agent with potential for treatment of onchocerciasis and lymphatic filariasis, with EC50 values of 1.5 nM in LDW1 cell lines and 15 nM in C6/36 cell lines[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2130750-59-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-111543. | |
| AN-3485 | AN-3485 is a benzoxaborole analogue and an orally active antagonist of the Toll-like pathway. AN-3485 can inhibit TLR-mediated inflammatory cytokine secretion and has significant anti-inflammatory activity. In addition, AN-3485 also has certain anti-tumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1213827-99-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18325. | |
| AN3661 | AN3661, a potent antimalarial lead compound, targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue subunit 3 (PfCPSF3). AN3661 inhibits Plasmodium falciparum laboratory-adapted strains (mean IC50=32 nM), Ugandan field isolates (mean ex vivo IC50=64 nM), and murine P. berghei and P. falciparum infections[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1268335-33-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-128204. | |
| AN5777 | AN5777 is a GSPT1 degrader. AN5777 significantly reduces GSPT1 through the ubiquitin-proteasome system. AN5777 induces G1 block and Apoptosis. AN5777 has antitumor activity [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 491586-42-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161696. | |
| AN7973 | AN7973 is the 6-carboxamide benzoxaborole, blocks intracellular parasite development and inhibits Cryptosporidium growth. AN7973 is orally active, possesses favorable safety, stability, and PK parameters, and is an exciting agent candidate for treating cryptosporidiosis. Uses: Scientific research. Category: Signaling pathways. CAS No. 1620899-32-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128337. | |
| ANA-12 | ANA-12 is a potent and selective TrkB antagonist with IC50s of 45.6 nM and 41.1 μM for the high and low affinity sites, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 219766-25-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-12497. | |
| Anabasine | Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-Anabasine; (+)-Anabasine. CAS No. 494-52-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1532. | |
| Anacardic Acid | Anacardic Acid, extracted from cashew nut shell liquid, is a histone acetyltransferase inhibitor, inhibits HAT activity of p300 and PCAF, with IC50s of ?8.5 μM and ?5 μM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hydroginkgolic acid; Ginkgolic Acid C15:0. CAS No. 16611-84-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2020. | |
| Anacardic acid triene | Anacardic acid triene is an ester product. Uses: Scientific research. Category: Signaling pathways. CAS No. 103904-73-0. Pack Sizes: 500 μg; 1 mg. Product ID: HY-126738. | |
| Anacetrapib | Anacetrapib is a potent CETP inhibitor, with IC50s of 7.9±2.5 nM and 11.8±1.9 nM for rhCETP and C13S CETP mutant, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-0859. CAS No. 875446-37-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12090. | |
| Anagliptin | Anagliptin (SK-0403) is a highly selective, potent, orally active inhibitor of dipeptidyl peptidase 4 (DPP-4), with an IC50 of 3.8 nM, and less selective at DPP-8 and DDP-9 with IC50s of 68 nM and 60 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SK-0403. CAS No. 739366-20-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14877. | |
| Anagrelide | Anagrelide is a potent inhibitor of phosphodiesterase type III (PDE3) (IC50=36?nM). Anagrelide, an imidazoquinazoline derivative, acts as an inhibitor of platelet aggregation. Anagrelide inhibits bone marrow megakaryocytopoiesis. Anagrelide decreases gastrointestinal stromal tumor (GIST) cell proliferation and promotes their apoptosis in vitro. Anagrelide is a platelet-lowering agent and plays in the antithrombopoietic action[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 68475-42-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0523. | |
| Anagrelide hydrochloride | Anagrelide hydrochloride (BL4162A) is a potent inhibitor of phosphodiesterase type III (PDE3) (IC50=36?nM). Anagrelide hydrochloride, an imidazoquinazoline derivative, acts as an inhibitor of platelet aggregation. Anagrelide hydrochloride inhibits bone marrow megakaryocytopoiesis. Anagrelide hydrochloride decreases gastrointestinal stromal tumor (GIST) cell proliferation and promotes their apoptosis in vitro. Anagrelide hydrochloride is a platelet-lowering agent and plays in the antithrombopoietic action[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BL4162A. CAS No. 58579-51-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0523A. | |
| Anagyrine | Anagyrine ((-)-Anagyrine) is a quinolizidine alkaloid that has been found in Lupinus albus. Anagyrine binds to muscarinic and nicotinic acetylcholine receptors with IC50 values of 132 and 2096 μM respectively. Anagyrine is a potent and effective desensitizer of nAChR, and Anagyrine can directly, without metabolism, desensitize nAChR[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Anagyrine; Monolupine; Rhombinine. CAS No. 486-89-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-121027. | |
| Anamorelin | Anamorelin (RC-1291) is an orally active Ghrelin receptor agonist with an EC50 of 0.74 nM. Anamorelin can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin can be used in the research of anorexia and cancer cachexia[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RC-1291; ONO-7643. CAS No. 249921-19-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14734. | |
| Anamorelin hydrochloride | Anamorelin (RC-1291) hydrochloride is an orally active Ghrelin receptor agonist with an EC50 of 0.74 nM. Anamorelin hydrochloride can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin hydrochloride can be used in the research of anorexia and cancer cachexia[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RC-1291 hydrochloride; ONO-7643 hydrochloride. CAS No. 861998-00-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14734A. | |
| Anandamide | Anandamide is an endocannabinoid. Anandamide modulates both neuronal and immune functions through two protein-coupled cannabinoid receptors (CB1 and CB2). Anandamide can activate numerous other receptors like PPARS, TRPV1, and GPR18/GPR55. Anandamide also has potential anti-fungal and anti-inflammatory activities. Anandamide can be used for the research of Alzheimers disease (AD) and ulcerative colitis[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AEA; Arachidonoyl ethanolamide. CAS No. 94421-68-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10863. | |
| Anandamide-d4 | Anandamide-d4 (AEA-d4) is the deuterium labeled Anandamide. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AEA-d4; Arachidonoyl ethanolamide-d4. CAS No. 946524-40-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-110072S. | |
| Anandamide-d8 | Anandamide-d8 is a deuterated labeled Anandamide[1]. Anandamide is an endocannabinoid. Anandamide modulates both neuronal and immune functions through two protein-coupled cannabinoid receptors (CB1 and CB2). Anandamide can activate numerous other receptors like PPARS, TRPV1, and GPR18/GPR55. Anandamide also has potential anti-fungal and anti-inflammatory activities. Anandamide can be used for the research of Alzheimers disease (AD) and ulcerative colitis[2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AEA-d8. CAS No. 924894-98-4. Pack Sizes: 500 μg (2.81 mM * 500 μL in Methyl acetate). Product ID: HY-10863S. | |
| Anastrozole | Anastrozole is a potent, highly selective aromatase inhibitor, which inhibits human placental aromatase with an IC50 of 15 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZD1033. CAS No. 120511-73-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14274. | |
| Anatibant hydrochloride | Anatibant (LF 16-0687; XY-2405) hydrochloride is a selective non-peptide bradykinin B2 receptor antagonist. Anatibant hydrochloride binds to the human, rat and guinea-pig recombinant B2 receptor with Ki values of 0.67 nM, 1.74 nM and 1.37 nM, respectively. Anatibant hydrochloride crosses the blood-brain barrier (BBB). Anatibant hydrochloride can be used in research on brain damage diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LF 16-0687 hydrochloride; XY-2405 hydrochloride. CAS No. 209788-45-4. Pack Sizes: 1 mg. Product ID: HY-121156A. | |
| ANAT inhibitor-2 | ANAT inhibitor-2 is a ANAT inhibitor for canavan disease, with an IC50 value of 20 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1048244-34-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139630. | |
| Anbenitamab | Anbenitamab (KN-026) is a bispecific antibody simultaneously targeting extracellular domains II and IV of human HER2. Anbenitamab blocks both ligand-dependent and ligand-independent HER2 signaling pathways. Anbenitamab mediates antibody-dependent cellular cytotoxicity (ADCC) via FcγIIIa binding. Ambrinitumab can be used in research for lung cancer, HER2-positive metastatic breast cancer (MBC), gastric cancer, and gastroesophageal junction cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KN-026. CAS No. 2367012-88-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99437. | |
| Andecaliximab | Andecaliximab is a recombinant chimeric IgG4 monoclonal antibody (mAb) targets matrix metalloproteinase 9 (MMP9). Andecaliximab shows the antifibrotic efficacy in idiopathic pulmonary fibrosis mouse models. Andecaliximab can be used for the research of gastric adenocarcinoma and idiopathic pulmonary fibrosis (IPF)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anti-MMP9 Reference Antibody (andecaliximab). CAS No. 1518996-49-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99351. | |
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