A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Cell-permeable. A slow, tight binding and highly selective inhibitor of iNOS (inducible nitric oxide synthase/NOS II) (Kd ≤7nM). In contrast, inhibition of nNOS and eNOS is weaker and rapidly reversible with K? values of 2 and 50uM respectively. Inhibits tumor growth in vivo. Prevents circulatory failure but not organ injury induced by endotoxin. Displays protective effects in oxygen-deprived brain slices. Group: Biochemicals. Alternative Names: N- (3- (Aminomethyl) benzyl) acetamidine 2HCl. Grades: Highly Purified. CAS No. 214358-33-5. Pack Sizes: 5mg, 25mg. US Biological Life Sciences.
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1400W Dihydrochloride
1400W dihydrochloride is the dihydrochloride form of 1400W (HY-18730). 1400W is a slow, tight binding, and highly selective inducible nitric-oxide synthase (iNOS) inhibitor, with a Kd value ≤ 7 nM. 1400W inhibits iNOS induction in microglial cells, and reduces generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex, and improving the spatial memory dysfunction caused by acute hypobaric hypoxia-reoxygenation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 214358-33-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18731.
1-[4-[(1,2,3,4-Tetrahydro-2-oxo-7-quinolinyl)oxy]butyl] Aripiprazole is a synthetic impurity of the drug aripiprazole (A771000). Aripiprazole is a novel atypical antipsychotic drug used in the treatment of schizophrenia. Aripiprazole Impurity 4. Group: Biochemicals. Grades: Highly Purified. CAS No. 1424857-63-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C36H42Cl2N4O4, Molecular Weight: 665.65. US Biological Life Sciences.
Aggregation-induced emission luminogens (AIEgen) were tailored to detect biological thiols. Maleimide is attached to the TPE core, giving TPE-Thiol.16. The reaction is inspired by the fast and efficient thiolene click reaction between maleimide and thiols, TPE-Thiol is not emissive in both solution and aggregated states, due to the photo-induced electron transfer from TPE to maleimide. However, reaction with thiol groups can interrupt the electron transfer process and turn-on the emission of TPE. TPE-Thiol can be used for labelling of protein carrying cysteine residues in the physiological media and poly(acrylamide) gel electrophoresis assays. Alternative Names: TPE-Thiol. CAS No. 1245606-71-6. Mole weight: 441.52. SMILES: CC(C=C1)=CC=C1/C(C2=CC=CC=C2)=C(C3=CC=CC=C3)/C4=CC=C(N5C(C=CC5=O)=O)C=C4. InChI: 1S/C31H23NO2/c1-22-12-14-25(15-13-22)30(23-8-4-2-5-9-23)31(24-10-6-3-7-11-24)26-16-18-27(19-17-26)32-28(33)20-21-29(32)34/h2-21H,1H3/b31-30+,CIMVFJJQFXGASK-NVQSTNCTSA-N.
14,15-Dehydro-21-acetyl Fluocinolone Acetonide is an intermediate in the synthesis of 14,15-Dehydro Fluocinolone Acetonide (D230135); an impurity of Fluocinolone Acetonide (F455800) which is a glucocorticoid and anti-inflammatory agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C26H30F2O7, Molecular Weight: 492.51. US Biological Life Sciences.
A derivative of Triamcinolone acetonide. A corticosteroid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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14,15-Dehydro budesonide
14,15-Dehydro budesonide. Group: Biochemicals. Alternative Names: (11b,16a)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4,14-triene-3,20-dione. Grades: Highly Purified. CAS No. 131918-64-4. Pack Sizes: 10mg, 20mg, 50mg, 100mg, 250mg. Molecular Formula: C25H32O6. US Biological Life Sciences.
Worldwide
14,15-Dehydro Fluocinolone Acetonide
14,15-Dehydro Fluocinolone Acetonide is an impurity of Fluocinolone Acetonide (F455800); a glucocorticoid and anti-inflammatory agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C24H28F2O6, Molecular Weight: 450.47. US Biological Life Sciences.
Worldwide
14,15-Dehydro Flurandrenolide
14,15-Dehydro Flurandrenolide is an impurity of Flurandrenolide (F598650), a glucocorticoid; antipsoriatic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C24H31FO6, Molecular Weight: 434.5. US Biological Life Sciences.
Worldwide
14,15-dehydro Leukotriene B4
14,15-dehydro Leukotriene B4 is an LTB4 receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 114616-11-4. Pack Sizes: 25ug, 50ug. Molecular Formula: C20H32O4, Molecular Weight: 336.47. US Biological Life Sciences.
Worldwide
14,15-Dehydro leukotriene B4
14,15-Dehydro leukotriene B4 is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. Synonyms: 14,15-dehydro LTB4; 5S,12R-dihydroxy-6Z,8E,10E-eicosatrien-14-ynoic acid. Grade: ≥97%. CAS No. 114616-11-4. Molecular formula: C20H30O4. Mole weight: 334.5.
14,15-Dehydro Triamcinolone Acetonide
14,15-Dehydro Triamcinolone Acetonide is a derivative of Triamcinolone acetonide. A corticosteroid. Group: Biochemicals. Grades: Highly Purified. CAS No. 1260149-96-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
14,15-Leukotriene C4
14,15-Leukotriene C4 is an acute inflammatory mediator. Group: Biochemicals. Grades: Highly Purified. CAS No. 75290-60-7. Pack Sizes: 25ug, 50ug. Molecular Formula: C30H47N3O9S, Molecular Weight: 625.77. US Biological Life Sciences.
Worldwide
14,15-Leukotriene E4
14,15-Leukotriene E4 is a Leukotriene that increases vascular permeability of human endothelial cell monolayers. Group: Biochemicals. Grades: Highly Purified. CAS No. 1000852-57-2. Pack Sizes: 25ug, 50ug. Molecular Formula: C23H37NO5S, Molecular Weight: 439.61. US Biological Life Sciences.
14:1 cholesteryl-d7 ester. Alternative Names: cholesteryl-d7 myristoleate. CAS No. 2342574-68-7. Purity: >99%. Product ID: ALCFA2342574687. Molecular formula: C41H63D7O2. Mole weight: 602.04. Alfa Chemistry - ISO 9001:32057 Certified.
1-[4-(1H-Imidazol-1-yl)phenyl]ethanamine
1-[4-(1H-Imidazol-1-yl)phenyl]ethanamine. Group: Biochemicals. Grades: Highly Purified. CAS No. 704877-65-6. Pack Sizes: 25mg, 50mg. Molecular Formula: C11H13N3, Molecular Weight: 187.24. US Biological Life Sciences.
Worldwide
1-(4-((2,4-dimethylphenyl)thio)phenyl)piperazine
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well as a Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: Vortioxetine impurity S; Piperazine, 1-[4-[(2,4-dimethylphenyl)thio]phenyl]-; Vonoprazan Impurity 08. CAS No. 1815608-51-5. Molecular formula: C18H22N2S. Mole weight: 298.45.
An intermediate in the syntheis of a metabolite of the anti-cancer drug Tamoxifen. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
An impurity of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. Synonyms: 1-(4-(2-Hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazol-5-yl)ethanone; 1227626-50-7; 1-[5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]ethanone. CAS No. 1227626-50-7. Molecular formula: C44H42N6O2. Mole weight: 686.84.
An impurity of Metoprolol, a β1 selective aryloxypropanolamine andrenergic antagonist. It is used in the treatment of a variety of cardiovascular disorder. Synonyms: Metoprolol Impurity 16. Grade: ≥95%. CAS No. 1416440-64-6. Molecular formula: C15H22O5. Mole weight: 282.33.
1-(4-(2-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide is used in the preparation of antiulcer agents, specifically 4-Substituted 2-guanidinothiazoles, which are reversible, competitive, and selective inhibitors of gastric H+,K+-ATPase. It is also used in the preparation of guanidinothiazole derivatives as Maillard reaction inhibitors and antioxidants. Group: Biochemicals. Grades: Highly Purified. CAS No. 123310-81-6. Pack Sizes: 500mg, 1g. Molecular Formula: C11H12N4OS; HBr, Molecular Weight: 248.31. US Biological Life Sciences.
1-(4-(2-methyl-6-oxopiperidin-1-yl)phenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one is an impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 1-[4-(2-Methyl-6-oxo-1-piperidinyl)phenyl]-3-(4-morpholinyl)-5,6-dihydro-2(1H)-pyridinone; 2(1H)-Pyridinone, 5,6-dihydro-1-[4-(2-methyl-6-oxo-1-piperidinyl)phenyl]-3-(4-morpholinyl)-. CAS No. 2098457-93-1. Molecular formula: C21H27N3O3. Mole weight: 369.46.
1-[4-(2-Phenylethyl)benzyl]naphthalene
1-[4-(2-Phenylethyl)benzyl]naphthalene. Alternative Names: 1-[4-(2-PHENYLETHYL)BENZYL]NAPHTHALENE;1-[4-(2-PHENETHYL)BENZYL]NAPHTHALENE;Phenylethylbenzylnaphthalene;1-(4-Phenethylbenzyl)naphthalene;2-Phenyl-1-[4-(1-naphthylmethyl)phenyl]ethane;4-(1-Naphthylmethyl)-(1,1'-ethylenebisbenzene);4-(1-Naphthylmethyl)bib. CAS No. 127833-53-8. Product ID: ACM127833538. Molecular formula: C25H22. Mole weight: 322.44. Alfa Chemistry - ISO 9001:32057 Certified.
1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(4-nitrophenyl)piperazine is an intermediate in the synthesis of derivatives of Itraconazole (I937500), an orally active antimycotic and antifungal compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 1437468-92-2. Pack Sizes: 10mg, 100mg. Molecular Formula: C29H28Cl2N6O5. US Biological Life Sciences.
1-[4-[3-[4-(4-Fluoro-2-hydroxybenzoyl)-1-piperidinyl]propoxy]-3-methoxyphenyl]-ethanone is a metabolite of Iloperidone (I267200) Combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Antipsychotic. Group: Biochemicals. Grades: Highly Purified. CAS No. 170170-50-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C24H28FNO5, Molecular Weight: 429.48. US Biological Life Sciences.
Worldwide
1,4:3,6-Dianhydro-2,5-di-O-ethyl-D-glucitol
1,4:3,6-Dianhydro-2,5-di-O-ethyl-D-glucitol. CAS No. 30915-81-2. Molecular formula: C10H18O4. Mole weight: 202.25.
1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol
1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol is a man-made entity applied in the research of kidney dysfunctions, ocular ailments, and cerebral edema alike. Synonyms: 1,4:3,6-Dianhydrosorbitol 2,5-dimethyl ether; 2,5-Di-O-methyl-1,4:3,6-dianhydro-D-glucitol; Isosorbide dimethyl ether; Dimethyl isosorbide. CAS No. 5306-85-4. Molecular formula: C8H14O4. Mole weight: 174.19.
1,4:3,6-Dianhydro-2,5-di-O-methyl-D-Iditol
1,4:3,6-Dianhydro-2,5-di-O-methyl-D-Iditol, a widely utilized chemical compound in the synthesis of insulin and several other medicinal compounds, possesses anti-diabetic and anti-inflammatory properties. Scientific research has explored its potential in managing diabetes and associated pathologies. Molecular formula: C8H14O4. Mole weight: 174.19.
1,4:3,6-Dianhydro-2,5-di-O-methyl-L-mannitol
1,4:3,6-Dianhydro-2,5-di-O-methyl-L-mannitol, a derivative of sugar alcohol, is known to serve as an essential cryoprotectant in the biopharmaceutical industry owing to its potential to enhance cell viability and maintain optimal functionality during the process of freezing and thawing. Its utility in preserving tissues and cells for research and transplantation purposes cannot be ignored due to its demonstrated utility and efficiency in this regard. Molecular formula: C8H14O4. Mole weight: 174.19.
1,4:3,6-Dianhydro-2-O-acetyl-D-glucitol
1,4:3,6-Dianhydro-2-O-acetyl-D-glucitol is an innovative compound specialized in the study of therapeutic solutions for diabetes. As a glucose regulator, it has an unparalleled ability to significantly improve insulin sensitivity and effectively alleviate postprandial hyperglycemia. This remarkable compound has been extensively present in a myriad of pharmaceutics and therapeutic interventions meticulously designed to optimize blood sugar control in individuals afflicted with diabetes. Synonyms: Isosorbide-2-acetate. CAS No. 13042-39-2. Molecular formula: C8H12O5. Mole weight: 188.18.
1,4:3,6-Dianhydro-2-O-methyl-D-glucitol
1,4:3,6-Dianhydro-2-O-methyl-D-glucitol, a remarkable and formidable sugar substitute that effectively avoids elevating blood sugar levels. This fantastic substitute is extensively used in preparing diabetic foods. Furthermore, it boasts the potential to deliver therapeutic benefits in the treatment of various conditions like neurodegenerative ailments and certain forms of cancer. Its virtues and properties are certainly not to be ignored nor underestimated. CAS No. 6941-54-4. Molecular formula: C7H12O4. Mole weight: 160.17.
1,4:3,6-Dianhydro-D-iditol
Isomaltitol, alternatively called 1,4:3,6-dianhydro-D-iditol, is a sugar substitute widely used in the food industry due to its low calorie count and low glycemic index, both of which make it a viable option for individuals with diabetes. This compound also has shown promise as a therapeutic agent for the treatment of ailments like hypertension and obesity, and as such, has piqued the interest of the scientific community. Synonyms: D-Isoidide. CAS No. 28948-16-5. Molecular formula: C6H10O4. Mole weight: 146.14.
1,4:3,6-Dianhydro-D-mannitol
1,4:3,6-Dianhydro-D-mannitol is a reagent used in the synthesis of new isomannide-based peptidomimetic as human tissue kallikrein 1 inhibitor using Ugi multicomponent reaction. It also functions as a chiral ligand for stereoselective synthesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 641-74-7. Pack Sizes: 1g, 5g. Molecular Formula: C6H10O4, Molecular Weight: 146.139999999999. US Biological Life Sciences.
Worldwide
1,4:3,6-Dianhydro-D-sorbitol 98+%
1,4:3,6-Dianhydro-D-sorbitol 98+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 652-67-5. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
1,4:3,6-Dianhydrogalactitol
2-Hydroxymethylene-4,6-anhydro-galactopyranose, or 1,4:3,6-Dianhydrogalactitol, is a promising antineoplastic molecule with demonstrated efficacy against diverse cancers, such as those afflicting the brain, prostate, and breast tissue. Its chemo-preventive, cytotoxic, and apoptotic functions render it a potent impetus in caspase-3 pathways, effectively preventing malignant cells from proliferating and promoting their programmed death. The multifaceted potential of 1,4:3,6-Dianhydrogalactitol presents a compelling vehicle for cancer treatment that warrants continued exploration. CAS No. 915288-38-9. Molecular formula: C6H10O4. Mole weight: 146.14.
1,4:3,6-Dianhydroiditol
1,4:3,6-Dianhydroiditol, also known as Dianhydrogalactitol, is used in research of chemotherapeutic agent targeting certain brain cancers. This alkylating agent can inhibit the replication of DNA, hence slowing growth and reproduction of cancer cells. Synonyms: L-Isoidide; (3S,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diol; Isoidide; 1,4:3,6-Dianhydro-L-iditol; Iditol, 1,4:3,6-dianhydro-. CAS No. 5627-19-0. Molecular formula: C6H10O4. Mole weight: 146.14.
1,4:3,6-Dianhydro-L-mannitol
1,4:3,6-Dianhydro-L-mannitol is colloquially referred to as Isosorbide, functioning predominantly as a nitrate-induced vasodilator. CAS No. 1394295-11-4. Molecular formula: C6H10O4. Mole weight: 146.14.
1-(4-(3-Bromophenyl)thiazol-2-yl)guanidine Hydrobromide is used in synthetic preparation of guanidinothiazoles as T-type calcium channel blockers. Group: Biochemicals. Grades: Highly Purified. CAS No. 1006032-17-2. Pack Sizes: 500mg, 1g. Molecular Formula: C10H9BrN4S; x HBr, Molecular Weight: 297.178090999999. US Biological Life Sciences.
One of the impurities of Dacomitinib. Dacomitinib, aslo known as PF-299 and PF-00299804 or PF299804, is an orally bioavailable, highly selective, second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor (EGFR) family of tyrosine kinases (ErbB family) with potential antineoplastic activity. Synonyms: 2-Pyrrolidinone, 1-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-5-hydroxy-; Dacomitinib Impurity WYQJ. Grade: ≥95%. CAS No. 2190490-31-2. Molecular formula: C19H16ClFN4O3. Mole weight: 402.81.
1-(4-(3-Chlorophenyl)thiazol-2-yl)guanidine Hydrobromide is used in the preparation of antiulcer agents, specifically 4-Substituted 2-guanidinothiazoles, which are reversible, competitive, and selective inhibitors of gastric H+,K+-ATPase. Also used in the preparation of substituted (thiazolylamino) tetra hydropyridopyrimidine derivatives useful as platelet aggregation inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 123310-66-7. Pack Sizes: 500mg, 1g. Molecular Formula: C10H9ClN4S; HBr, Molecular Weight: 252.728091. US Biological Life Sciences.
1-[4-(3-Hydroxypropoxy)-3-methoxyphenyl]-ethanone is an intermediate used to prepare Iloperidone derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 207298-39-3. Pack Sizes: 100mg, 250mg. Molecular Formula: C12H16O4, Molecular Weight: 224.25. US Biological Life Sciences.
1-[4-(3-Hydroxypropoxy)-3-methoxyphenyl]-ethanone-d3 is 1-[4-(3-Hydroxypropoxy)-3-methoxyphenyl]-ethanone (H952135) which is an intermediate used to prepare Iloperidone derivatives. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C12H13D3O4, Molecular Weight: 227.27. US Biological Life Sciences.
1-(4-(3-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide shows antiulcer activity. Also used in the preparation of other antiulcer agents such as 4-Substituted 2-guanidinothiazoles which are reversible, competitive, and selective inhibitors of gastric H+,K+-ATPase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg, 1g. Molecular Formula: C11H12N4OS; HBr, Molecular Weight: 248.31. US Biological Life Sciences.