A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Y-1005 is a quinone antibiotic isolated from Fusiform yeast stiain BY1. It is effective against gram-positive and -negative bacteria, as well as yeast. Molecular formula: C16H16O6. Mole weight: 304.29.
Y 134
Y 134. Group: Biochemicals. Grades: Purified. CAS No. 849662-80-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Y15
Y15 is a potent and specific inhibitor of focal adhesion kinase (FAK) that inhibits its autophosphorylation activity, decreases the viability of cancer cells, and blocks tumor growth. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FAK Inhibitor 14. CAS No. 4506-66-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-12444.
Y16
Y16 is a specific inhibitor of Leukemia-associated Rho guanine nucleotide exchange factor (LARG) with a Kd value of 76 nM. Y16 is active in blocking the interaction of LARG and related G-protein-coupled Rho GEFs with RhoA. Y16 shows no detectable effect on other diffuse B-cell lymphoma (Dbl) family Rho GEFs, Rho effectors, or a RhoGAP[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 429653-73-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-12649.
Y1693
Y1693 is an orally active RANKL inhibitor with a Kd of 5.03 μM for hRANKL. Y1693 inhibits the activation of the downstream c-fos/NFATc1 signaling pathway by blocking its interaction with RANK. Y1693 significantly inhibits RANKL-induced osteoclast differentiation, F-actin ring formation and bone resorptive activity, while downregulating the mRNA and protein expressions of TRAP, cathepsin K, c-fos and NFATc1. Y1693 shows no obvious cytotoxicity to bone marrow-derived macrophages and osteoclast precursor cells, and exhibits favorable ADME properties. Y1693 improves ovariectomy-induced osteoporosis in mice and reverses ligation-induced periodontal alveolar bone loss. Y1693 is applicable to research related to osteoporosis and periodontal diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2812381-74-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-182757.
Y-20XP
Y-20XP.
Y-25130 hydrochloride
Y-25130 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 123040-16-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Y-25X
Y-25X.
Y-26763
Y-26763. Group: Biochemicals. Grades: Purified. CAS No. 127408-31-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Y-27152
Y-27152. Group: Biochemicals. Grades: Purified. CAS No. 127408-30-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Y-27632
Y-27632 is a ROCK inhibitor with Ki values of 220 nM and 300 nM for ROCK1 and ROCK2, respectively. Y-27632 exerts anti-inflammatory and immunomodulatory effects in systemic lupus erythematosus models by inhibiting the ROCK/NF-κB pathway. Y-27632 enhances autophagy by inhibiting the AKT/mTOR pathway, thereby inducing apoptosis apoptosis in oral squamous cell carcinoma. Y-27632 induces the formation of tunneling nanotubes in ARPE-19 cells and significantly enhances mitochondrial transfer through these channels. Y-27632 promotes neurite outgrowth in PC12 cells by activating the Rac1/NOX1/ROS/AKT/PAK1 signaling cascade[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 146986-50-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10071.
Y-27632 is a selective ROCK1 and ROCK2 inhibitor with a Ki of 140 nM and 300nM in a cell-free assay, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK. Group: Inhibitors. CAS No. 146986-50-7. Pack Sizes: 5mg. Product ID: S6390. Formula: C14H21N3O. Smiles: CC(N)C1CCC(CC1)C(=O)NC2=CC=NC=C2. Storage Conditions: 3 years -20°C powder? 2 years -80°C in solvent.
A labeled Rho kinase inhibitor (ROCK) for the treatment of ischemia-reperfusion disorders. Group: Biochemicals. Alternative Names: trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinyl-cyclohexanecarboxamide-d4 Dihydrochloride Monohydrate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Y-27632 dihydrochloride
Y-27632 dihydrochloride is an orally active and ATP-competitive ROCK (Rho-kinase) inhibitor (ROCK-I Ki=220 nM; ROCK-II Ki=300 nM). Y-27632 dihydrochloride shows antiepileptic effects[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 129830-38-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10583.
Y-27632 Dihydrochloride
Y-27632 is a selective inhibitor of Rho-associated coiled-coil forming protein serine/threonine kinase (ROCK) family of protein kinases that selectively competes with ATP for binding to the catalytic site. It is reported to diminish dissociation-induced apoptosis, increase cloning efficiency, and facilitate subcloning after gene transfer in human embryonic stem cells (hES). Group: Biochemicals. Alternative Names: trans-4- [ (1R) -1-Aminoethyl] -N-4-pyridinylcyclohexane carboxamide Dihydrochloride; (+) - (R) -trans-4- (1-aminoethyl) -N- (4-pyridyl) cyclohexanecarboxamide Dihydrochloride; (+) -trans-N- (4-Pyridyl) -4- [ (R) -1-aminoethyl] cyclohexanecarboxamide Dihydrochloride. Grades: Highly Purified. CAS No. 129830-38-2. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C??H??N?O; 2(HCl), Molecular Weight: 320.3. US Biological Life Sciences.
Worldwide
Y-27632 Dihydrochloride
Y-27632 2HCl is a selective ROCK1 and ROCK2 inhibitor with a Ki of 140 nM and 300nM in a cell-free assay, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK. Group: Inhibitors. CAS No. 129830-38-2. Pack Sizes: 2mg. Product ID: S1049. Formula: C14H21N3O.2HCl. Smiles: CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl. Storage Conditions: 3 years-20°C powder.
United States; Europe
Y-27632 dihydrochloride (GMP)
Y-27632 dihydrochloride (GMP) is the GMP level of Y-27632 dihydrochloride (HY-10583). GMP guidelines are used to produce Y-27632 dihydrochloride (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. Y-27632 dihydrochloride is an orally active and ATP-competitive ROCK (Rho-kinase) inhibitor with antiepileptic effect[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 129830-38-2. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-10583G.
Y-27632 dihydrochloride (Standard)
Y-27632 dihydrochloride (Standard) is the analytical standard of Y-27632 dihydrochloride. Y-27632 dihydrochloride is an orally active and ATP-competitive ROCK (Rho-kinase) inhibitor (ROCK-I Ki=220 nM; ROCK-II Ki=300 nM). Y-27632 dihydrochloride shows antiepileptic effects[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 129830-38-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10583R.
Y-29794 oxalate
Y-29794 oxalate. Group: Biochemicals. Grades: Purified. CAS No. 146794-84-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Y-320 is a potent, orally active phenylpyrazoleanilide immunomodulator. Y-320 inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM. Y-320 enhances TP53, DMD, and COL17A1 PTC readthrough by G418 and increases cellular protein levels and protein synthesis. Y-320 concomitants use of with a low dose of Paclitaxel (HY-B0015) significantly sensitized multidrug resistance (MDR) tumors by inducing G2/M phase arrest and apoptosis. Y-320 can be used for research of rheumatoid arthritis (RA) and cancer[1][2][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 288250-47-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15898.
Y-33075
Y-33075 is a selective ROCK inhibitor derived from Y-27632, and is more potent than Y-27632, with an IC50 of 3.6 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Y-39983 free base. CAS No. 199433-58-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10067.
Y-33075 dihydrochloride
Y-33075 dihydrochloride is a selective ROCK inhibitor with an IC50 of 3.6 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 173897-44-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10069.
Y3Al5O12 nanopowder
Y3Al5O12 nanopowder. Purity: 99+%.
Yacon powder
Yacon powder is a brown powder, using fresh yacon, maximize the retention of nutrients. It has a fresh, vivid yacon unique flavor. Easy to use, mellow taste. Group: Others. Yacon powder. Cat No: EXTC-148.
yadanziolide A
Yadanziolide A is extracted from seeds of Brucea javanica. It has strong antiviral activity. Synonyms: yadanziolide A; 95258-14-3; (1R,2R,3R,6R,8S,12S,13S,14R,15R,16S,17R)-2,3,12,15,16-Pentahydroxy-17-(hydroxymethyl)-9,13-dimethyl-5,18-dioxapentacyclo[12.5.0.01,6.02,17.08,13]nonadec-9-ene-4,11-dione; CHEMBL2037039; HY-N4210; AKOS040760154; AC-34985; DA-61914; MS-27518; CS-0032442; G18579; (1R,2R,3R,6R,8S,12S,13S,14R,15R,16S,17R)-2,3,12,15,16-pentahydroxy-17-(hydroxymethyl)-9,13-dimethyl-5,18-dioxapentacyclo[12.5.0.0(1),?.0(2),(1)?.0?,(1)(3)]nonadec-9-ene-4,11-dione. Grade: 98.0%. CAS No. 95258-14-3. Molecular formula: C23H30O9. Mole weight: 450.5.
Yadanziolide C
Yadanziolide C is extracted from the seeds of Brucea javanica. It could induce differentiation with cultured HL-60 promyelocytic leukemia cells. Synonyms: (+)-13,20-Epoxy-1α,11β,12α,14,15β-pentahydroxypicrasa-3-ene-2,16-dione. Grade: 96.5%. CAS No. 95258-12-1. Molecular formula: C20H26O9. Mole weight: 410.41.
Yadanzioside A
Yadanzioside A is extracted from the seeds of Brucea javanica. It is a biochemical chemical and shows antileukemic activity. Synonyms: methyl dihydroxy-dimethyl-(3-methylbutanoyloxy)-dioxo-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-[?]carboxylate; (11beta,12alpha,15beta)-13,20-Epoxy-2-(beta-D-glucopyranosyloxy)-11,12-dihydroxy-15-(3-methyl-1-oxobutoxy)-3,16-dioxo-picras-1-en-21-oic acid methyl ester; Picras-1-en-21-oic acid, 13,20-epoxy-2-(beta-D-glucopyranosyloxy)-11,12-dihydroxy-15-((3-methyl-1-oxobutoxy)-3,16-dioxo-, methyl ester, (11-beta,12-alpha,15-beta)-. Grade: 98.0%. CAS No. 95258-15-4. Molecular formula: C32H44O16. Mole weight: 684.68.
Yadanzioside F
Yadanzioside F is extracted from the seeds of Brucea javanica. It is a biochemical chemical and shows antileukemic activity. Synonyms: Picras-1-en-21-oic acid, 15-(acetyloxy)-11,12-dihydroxy-3,16-dioxo-13,20-epoxy-2-(beta-D-glucopyranosyloxy)-, methyl ester, (11-beta,12-alpha,15-beta)-. Grade: 98.0%. CAS No. 95258-11-0. Molecular formula: C29H38O16. Mole weight: 642.60.
Yadanzioside I
Yadanzioside I is extracted from the seeds of Brucea javanica. It has strong antiviral activity. Synonyms: Yadanzioside I; 99132-95-3; AKOS040762515; DA-68760; B0005-267620. Grade: 96.0%. CAS No. 99132-95-3. Molecular formula: C29H38O16. Mole weight: 642.6.
Yadanzioside K
Yadanzioside K is extracted from the seeds of Brucea javanica. Synonyms: Picras-3-en-21-oicacid, 15-[[(2E)-4-(acetyloxy)-3,4-dimethyl-1-oxo-2-pentenyl]oxy]-13,20-epoxy-3-(b-D-glucopyranosyloxy)-11,12-dihydroxy-2,16-dioxo-, methyl ester, (11b,12a,15b)- (9CI). Grade: 97.0%. CAS No. 101559-98-2. Molecular formula: C36H48O18. Mole weight: 768.76.
Yadanzioside M
Yadanzioside M is extracted from the seeds of Brucea javanica. It has antitumor activity. Synonyms: Methyl benzoyloxy-dihydroxy-dimethyl-dioxo-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-[?]carboxylate; Picras-1-en-21-oic acid, 15-(benzoyloxy)-13,20-epoxy-2-(beta-D-glucopyranosyloxy)-11,12-di- hydroxy-3,16-dioxo-, methyl ester, (11beta,12alpha,15beta)-. Grade: 97.0%. CAS No. 101559-99-3. Molecular formula: C34H40O16. Mole weight: 704.68.
Yaddle1
Yaddle1 is an agonist of the mechano-activated ion channel (Piezo1) with a half-maximal effective concentration (MEC50) of 0.40 μM. Yaddle1 can significantly trigger Ca2+ inflow in T cells and induce T cell activation response. Yaddle1 can be used in the study of vaccine adjuvants[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3041134-13-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162501.
Yam Extract
Yam extract contains diosgenin, which has anti-fatigue, anti-inflammatory, anti-stress. Yam extract is antispasmodic, and could be helpful for nausea of pregnant women (morning sickness), spasmodic hiccough and asthma. Group: Others. Mole weight: 414.63. Wild Yam Extract; Rhizoma Dioscoreae. Cat No: EXTC-017.
Yamogenin
Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes. Yamogenin is a steroidal saponin that can be obtained from plant species with in vitro cytotoxicity, antioxidant, and antimicrobial properties. Yamogenin induces cell death via the extrinsic and intrinsic way of apoptosis. Yamogenin inhibits protein denaturation with an IC50 of 1421.92 μg/mL. Yamogenin can be studied in research on gastric cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Neodiosgenin. CAS No. 512-06-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2078.
Yamogenin
Yamogenin is a sapogenin compound found in the plant amber fenugreek, with steroid framework, that maintains antidiabetogenic activity. They also provide framework for the synthesis of a potential inhibitor of metallo- β-lactamase-1 which is a major target in the treatment of diseases involving gram-negative bacteria. Group: Biochemicals. Alternative Names: (22R,25S)-(20α)-Spirost-5-en-3 β-ol; Jamogenin; NSC 226132; (25S)-Spirost-5-en-3 β-ol; Neodiosgenin; (3 β,25S)-Spirost-5-en-3-ol. Grades: Highly Purified. CAS No. 512-06-1. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Yangonin
A lactone isolated from the Kava plant (Piper methysticum). Group: Biochemicals. Alternative Names: 4-Methoxy-6-[(1E)-2-(4-methoxyphenyl)ethenyl]-thoxy-α-pyrone. Grades: Highly Purified. CAS No. 500-62-9. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Yangonin
Yangonin exhibits affinity for the human recombinant cannabinoid CB1 receptor with an IC50 and a Ki of 1.79 μM and 0.72 μM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 500-62-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N0919.
Yangonin-d3
Yangonin-d3. Group: Biochemicals. Alternative Names: 4-Methoxy-6-[(1E)-2-(4-methoxyphenyl)ethenyl]-. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C16H15D3O4. US Biological Life Sciences.
Worldwide
YAP Antibody [C6K11]
YAP,YAP1. Group: Antibodies. Alternative Names: YAP,YAP1. Pack Sizes: 20uL. Product ID: F0366. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years.
United States; Europe
yapsin 1
In peptidase family A1 of pepsin, and weakly inhibited by pepstatin. Can partially substitute for kexin in a deficient strain of yeast. The homologous product of the Mkc7 gene (Saccharomyces cerevisiae) has similar catalytic activity and has been termed yapsin 2. Group: Enzymes. Synonyms: yeast aspartic protease 3; Yap3 gene product (Saccharomyces cerevisiae). Enzyme Commission Number: EC 3.4.23.41. CAS No. 205132-58-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4278; yapsin 1; EC 3.4.23.41; 205132-58-7; yeast aspartic protease 3; Yap3 gene product (Saccharomyces cerevisiae). Cat No: EXWM-4278.
YAP/TAZ inhibitor-1
YAP/TAZ inhibitor-1 is a YAP/TAZ inhibitor extracted from patent WO2017058716A1, Compound 1, has an IC50 of <0.100 μΜ in firefly luciferase assay[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2093565-23-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111429.
YAP/TAZ inhibitor-2
YAP/TAZ inhibitor-2 is a potent and orally active TEAD-YAP/TAZ inhibitor with an EC50 value of 3 nM. YAP/TAZ inhibitor-2 shows anti-proliferative activity. YAP/TAZ inhibitor-2 shows antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2762617-31-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147322.
YAP-TEAD-IN-1
YAP-TEAD-IN-1 is a potent and competitive inhibitor of?YAP-TEAD interaction (IC50=25 nM). YAP-TEAD-IN-1 is a 17mer peptide and shows a higher the binding affinity to TEAD1 (Kd=15 nM) than YAP (50-171) (Kd=40 nM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1659305-78-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2244.
YAP-TEAD Inhibitor 1
YAP-TEAD Inhibitor 1 is a potent inhibitor of YAP-TEAD interaction with IC50 value of 25 nM. Synonyms: YAP-TEAD-IN-1; YAP-TEAD (Peptide 17). Grade: 98%. CAS No. 1659305-78-8. Molecular formula: C93H144ClN23O21S2. Mole weight: 2019.86.
YAP-TEAD Inhibitor 1 (Peptide 17)
YAP-TEAD Inhibitor 1 (Peptide 17) is a YAP-TEAD protein-protein interaction inhibitor which has potential usage in treatment of YAP-involved cancers with IC50 of 25 nM. Group: Inhibitors. CAS No. 1659305-78-8. Pack Sizes: 1mg. Product ID: S8164. Formula: C93H144ClN23O21S2. Smiles: CCCCC1NC(=O)C(CCCCN)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC(C)C)NC(=O)C(CCSSCC(NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(C)NC(=O)C3CCCN3C1=O)C(=O)NC(CCCCN)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)NC(CCC(O)=O)C(N)=O)NC(=O)C(C. Storage Conditions: 2 years -80 in solvent.
It is an antifungal antibiotic produced by the strain of Streptomyces sp. TP-A0356. Its anti-fungal activity against Aspergillus fumigatus, Aspergillus flavus, Aspergillus Niger, Candida albicans and Cryptococcus neoformans is stronger than Amphotericin B and Etraconazole (MIC is 0.0039-0.0156 μg/mL). It also has strong cytotoxicity to P388, HeLa, HEL and other tumor cells (IC50 is 0.01-0.33 μg/mL). Synonyms: (+)-yatakemycin; Ethanethioic acid, S-(6-(((7bR,8aS)-1,2,4,5,8,8a-hexahydro-2-((6-hydroxy-5-methoxy-1H-indol-2-yl)carbonyl)-4-oxocyclopropa(c)pyrrolo(3,2-e)indol-6-yl)carbonyl)-3,6,7,8-tetrahydro-5-hydroxy-4-methoxybenzo(1,2-b:4,3-b')dipyrrol-2-yl) ester. CAS No. 606136-98-5. Molecular formula: C35H29N5O8S. Mole weight: 679.70.
Yatein
Yatein. CAS No. 40456-50-6. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
YB-0158
YB-0158 (Wnt pathway inhibitor 2) is a reverse-turn peptidomimetic and a potent colorectal cancer stem cell (CSC) targeting agent. YB-0158 disrupts Sam68-Src interactions and induces apoptosis in CRC cells. Anti-cancer activities[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Wnt pathway inhibitor 2. CAS No. 1144043-83-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136541.
YC-001
YC-001 is an inverse agonist and antagonist of rod opsin. YC-001 reversibly binds rod opsin and stabilizes the rod opsin structure. YC-001 protects mice from bright light-induced retinal degeneration. YC-001 has the potential for the research of retinal degeneration[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 748778-73-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124717.
YC-1 (Lificiguat)
Lificiguat (YC-1) is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase(sGC) and an inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alpha). Group: Inhibitors. CAS No. 170632-47-0. Pack Sizes: 10mg. Product ID: S7958. Formula: C19H16N2O2. Smiles: C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=N2)C4=CC=C(O4)CO. Storage Conditions: 2 years -80 in solvent.
United States; Europe
YD2
Alfa Chemistry offers YD2 products for various research purposes. Please contact us by email if you do not find the specification you are looking for on this page. Alternative Names: [5-[Bis(4-hexylphenyl)amino]-15-[2-(4-carboxyphenyl)ethynyl]-10,20-bis(3,5-di-tert-butylphenyl)porphyrinato]zinc(II). CAS No. 1201915-91-4. Molecular formula: C81H89N5O2Zn. Mole weight: 1230.02. Purity: >97.0%(T)(HPLC). IUPAC Name: zinc;4-[2-[10,20-bis(3,5-ditert-butylphenyl)-15-(4-hexyl-N-(4-hexylphenyl)anilino)porphyrin-22,24-diid-5-yl]ethynyl]benzoic acid. SMILES: CCCCCCC1=CC=C(C=C1)N(C2=CC=C(C=C2)CCCCCC)C3=C4C=CC(=N4)C(=C5C=CC(=C(C6=NC(=C(C7=CC=C3[N-]7)C8=CC(=CC(=C8)C(C)(C)C)C(C)(C)C)C=C6)C#CC9=CC=C(C=C9)C(=O)O)[N-]5)C1=CC(=CC(=C1)C(C)(C)C)C(C)(C)C.[Zn+2]. InChI: InChI=1S/C81H90N5O2.Zn/c1-15-17-19-21-23-53-27-34-63(35-28-53)86(64-36-29-54(30-37-64)24-22-20-18-16-2)76-72-45-43-70(84-72)74(57-47-59(78(3,4)5)51-60(48-57)79(6,7)8)68-41-39-66(82-68)65(38-31-55-25-32-56(33-26-55)77(87)88)67-40-42-69(83-67)75(71-44-46-73(76)85-71)58-49-61(80(9,10)11)52-62(50-58)81(12,13)14;/h25-30,32-37,39-52H,15-24H2,1-14H3,(H2-,82,83,84,85,87,88);/q-1;/p-1.
YD23
YD23 is a selective SMARCA2 PROTAC degrader with DC50 values of 64 nM and 297 nM in H1792 cells and H1975 cells. YD23 induces degradation of SMARCA2, which is synthetic lethal to SMARCA4. YD23 reduces chromatin accessibility only in SMARCA4 deficient cells, including cell cycle and cell growth regulatory genes. YD23 selectively inhibits growth of SMARCA4 mutant lung cancer cells. YD23 has potent tumor growth inhibitory activity in SMARCA4-mutant xenografts. YD23 can be used for the study of non-small cell lung cancer (NSCLC)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2951015-29-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153361.
YD54 is a PROTAC based SMARCA2 degrader with a DC50 of 3.5 nM (Red: SMARCA2 degrader (HY-44012B), black: linker, Blue: E3 ligase ligand)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2951015-30-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-168221.
YDR1
YDR1 is a potent PROTAC SMARCA2 degrader, with the DC50 of 7.7 nM. YDR1 plays an important role in SMARCA4 mutant cancers(Sturcture Note:(Blue: Cereblon ligand (HY-W087383), Black: linker?Pink: SMARCA2 ligand (HY-44012B))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2951015-31-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-168215.
YE 120
YE 120. Group: Biochemicals. Grades: Highly Purified. CAS No. 383124-82-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
YE6144
YE6144 free base is a selective prototypical interferon regulatory factor 5 (IRF5) inhibitor. YE6144 free base suppresses the disease course and is especially effective in remission maintenance in a mouse model of systemic lupus erythematosus (SLE). YE6144 free base can be used for SLE research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3065657-02-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-150095.
Yeast Beta Glucan (1,3/1,6) 70% & 85%
Yeast Beta Glucan (1,3/1,6) 70% & 85%.
CA, FL & NJ
Yeast extract
100g Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: N/A. CAS No. 8013-1-2. Prepack ID 35752308-100g. See USA prepack pricing.
Yeast extract
1kg Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: N/A. CAS No. 8013-1-2. Prepack ID 35752308-1kg. See USA prepack pricing.
Yeast extract
Yeast extract is a concentrate of the soluble components of yeast, especially Saccharomyces cerevisiae. Yeast extract is rich in nutritional components such as partially hydrolyzed proteins, free amino acids, B vitamins, and minerals. As a food ingredient, Yeast extract has both nutritional and flavoring properties. Yeast extract can also promote wound healing[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 8013-1-2. Pack Sizes: 50 g; 100 g. Product ID: HY-153126.
Yeast Extract Polar
Yeast Extract Polar. Alternative Names: Yeast Polar Lipid Extract (S. cerevisiae). Product ID: ALCFA00002. Alfa Chemistry - ISO 9001:32057 Certified.