A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
J10-1 is a hapten small molecule. J10-1 accelerates peptide exchange in MHC class II molecules in an HLA-DM-independent manner, and its effect is not affected by the polymorphism of the P1 pocket of MHC class II molecules. J10-1 enhances the processes of peptide dissociation, peptide binding and peptide association of MHC class II molecules on the surface of B cells. J10-1 can be used for research on immunoregulation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1069110-72-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157269.
J 104129 Fumarate
Potent M3 muscarinic receptor antagonist that displays ~ 120-fold selectivity over M2 receptors (Ki values are 4.2, 19 and 490nM for human M3, M1 and M2 receptors respectively). Exhibits >250-fold bronchial selectivity; inhibits ACh-induced bronchoconstriction but not ACh-induced bradycardia (KB values are 3.3 and 170 nM for rat trachea M3 and rat right atria M2 receptors respectively). Group: Biochemicals. Alternative Names: (α R) -α -Cyclopentyl-α -hydroxy-N- [1- (4-methyl-3-pentenyl) -4-piperidinyl] benzeneacetamide Fumarate; (α R) -α -Cyclopentyl-α -hydroxy-N- [1- (4-methyl-3-pentenyl) -4-piperidinyl] benzeneacetamide (2E)-2-Butenedioate (1:1) (salt) (9CI). Grades: Highly Purified. CAS No. 257603-40-0. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?; (C?H?O?), Molecular Weight: 500.63. US Biological Life Sciences.
Worldwide
J 113863
J 113863. Group: Biochemicals. Grades: Purified. CAS No. 353791-85-2. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences.
Worldwide
J-113863
J-113863 is a potent and selective CCR1 antagonist with IC50 values of 0.9 nM and 5.8?nM for human and mouse CCR1 receptors, respectively. J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptors. Anti-inflammatory effect[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 353791-85-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103360.
J14
J14 is a reversible sulfiredoxin inhibitor with an IC50 of 8.1 μM. J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1043854-13-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135008.
J-2156
J-2156 is a somatostatin receptor type 4 agonist. Synonyms: J 2156; J-2156 TFA salt. CAS No. 848647-56-3. Molecular formula: C24H28N4O4S. Mole weight: 468.57.
J-2156
J-2156 is a high potent, selective somatostatin receptor type 4 (SST4 receptor) agonist with IC50s of 0.05 nM and 0.07 nM for human and rat SST4 receptors, respectively. J-2156 is used for the relief of mechanical allodynia and mechanical hyperalgesia in the ipsilateral hindpaws in rats[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 848647-56-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111615.
J-2156 TFA
J-2156 TFA is a high potent, selective somatostatin receptor type 4 (SST4 receptor) agonist with IC50s of 0.05 nM and 0.07 nM for human and rat SST4 receptors, respectively. J-2156 TFA has anti-inflammatory activity and it is used for the relief of mechanical allodynia and mechanical hyperalgesia in the ipsilateral hindpaws in rats[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2387505-73-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111615A.
J51
Band gap: 1.99 eV. Alternative Names: Poly[(5,6-difluoro-2-octyl-2H-benzotriazole-4,7-diyl)-2,5-thiophenediyl[4,8-bis[5-(2-hexyldecyl)-2-thienyl]benzo[1,2-b:4,5-b']dithiophene-2,6-diyl]-2,5-thiophenediyl]. CAS No. 1393529-03-7. Molecular formula: (C72H93F2N3S6)n.
j-8 Hydrochloride
j-8 Hydrochloride. Alternative Names: (N-8-AMINOOCTYL)-5-IODO-1-NAPHTHALENESULFONAMIDE HCL;J-8 HYDROCHLORIDE;J-8;N-(8-Aminooctyl)-5-iodo-1-naphthalenesulfonamide hydrochloride. CAS No. 187937-24-2. Product ID: ACM187937242. Molecular formula: C18H25IN2O2S.HCl. Mole weight: 496.83. Alfa Chemistry - ISO 9001:32057 Certified.
J9Z38
J9Z38 is a metabolite of Cyantraniliprole (HY-12779), a broad-spectrum agrochemical insecticide belonging to the anthranilic diamide insecticide class. Cyantraniliprole effectively controls the growth of various pests on fruits, vegetables, cereals and other crops. Thus, J9Z38 is a key indicator for indirect detection and evaluation of Cyantraniliprole residue levels[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1414864-34-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160758.
JA2
JA2 is an inhibitor of metalloendopeptidase 24.15 that can potentiate the hypotensive response to bradykinin in rat[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 277333-45-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-164704.
JA310
JA310, a chemical probe, is a highly selective MST3 kinase inhibitor. JA310 has high cellular potency against MST3 with an EC50 value of 106 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3022928-90-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-160211.
JAB-2485
JAB-2485 is an orally active and selective Aurora kinase A (AURKA) inhibitor with an IC50 value of 0.327 nM. JAB-2485 exhibits inhibitory activity against various tumor cell lines such as neuroblastoma, triple-negative breast cancer, small cell lung cancer, and epithelial ovarian cancer. JAB-2485 can induce cell cycle arrest and apoptosis in tumor cells. JAB-2485 has antitumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2899209-55-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-157396.
JAB-3068
JAB-3068 (SHP2-IN-6) is a potent SHP2 inhibitor, extracted from patent WO2017211303A1, compound 7, has an IC50 of 25.8 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SHP2-IN-6. CAS No. 2169223-48-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131132.
Jacaric acid
Jacaric acid. Alternative Names: 8(Z),10(E),12(Z)-Octadecatrienoic Acid. CAS No. 28872-28-8. Purity: >95.0%. Product ID: FFC-AR-28872288. Molecular formula: C18H30O2. Mole weight: 278.43. IUPAC Name: (8Z,10E,12Z)-octadeca-8,10,12-trienoic acid. Alfa Chemistry - ISO 9001:32057 Certified.
Jaceosidin
Jaceosidin is a flavonoid isolated from Artemisia vestita, induces apoptosis in cancer cells, activates Bax and down-regulates Mcl-1 and c-FLIP expression[1]. Jaceosidin exhibits anti-cancer[2], anti-inflammatory activities, decreases leves of inflammatory markers, and suppresses COX-2 expression and NF-κB activation[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18085-97-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0831.
Jaceosidin
Jaceosidin is a natural flavonoid isolated from the herbs of Artemisia arctica. Jaceosidin exhibits the activities of anti-oxidative, anti-inflammatory and anti-neuroinflammation. Uses: Anti-oxidative, anti-inflammatory, anti-neuroinflammation. Synonyms: 5,7-dihydroxy-2-(4-hydroxy-3-methoxy-phenyl)-6-methoxy-chromen-4-one. Grade: >98%. CAS No. 18085-97-7. Molecular formula: C17H14O7. Mole weight: 330.29.
Jaceosidin
Jaceosidin. Group: Biochemicals. Grades: Plant Grade. CAS No. 18085-97-7. Pack Sizes: 10mg. Molecular Formula: C17H14O7, Molecular Weight: 330.29. US Biological Life Sciences.
Worldwide
Jaceosidin impurity 1
Jaceosidin impurity 1. Uses: For analytical and research use. CAS No. 1404192-74-0. Molecular formula: C17H16O8. Mole weight: 348.31. Catalog: APB1404192740.
Jaceosidin impurity 2
Jaceosidin impurity 2. Uses: For analytical and research use. CAS No. 7084-24-4. Molecular formula: C21H21ClO11. Mole weight: 484.84. Catalog: APB7084244.
Jacid urea sodium salt
Jacid urea sodium salt. CAS No. 110392-53-5. Product ID: ACM110392535. Alfa Chemistry - ISO 9001:32057 Certified.
Jacobine impurity 1
Jacobine impurity 1. Uses: For analytical and research use. CAS No. 38710-25-7. Molecular formula: C18H25NO7. Mole weight: 367.4. Catalog: APB38710257.
Jacobine impurity 2
Jacobine impurity 2. Uses: For analytical and research use. Molecular formula: C18H22D3NO6. Mole weight: 354.42. Catalog: APB12289.
Jadomycin B
Jadomycin B is an angucyclic natural product produced by Streptomyces venezuelae ISP5230. It exhibits antimicrobial, antitumor activity and inhibits aurora-B kinase and DNA cleaving. It was also shown to be effective against a variety of staphylococci. Synonyms: 1-(sec-butyl)-12-((4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-7-hydroxy-5-methyl-8H-benzo[b]oxazolo[3,2-f]phenanthridine-2,8,13(1H,3aH)-trione; 8H-Benzo(b)oxazolo(3,2-f)phenanthridine-2,8,13(1H,3aH)-trione, 12-((2,6-dideoxyhexopyranosyl)oxy)-7-hydroxy-5-methyl-1-(1-methylpropyl)-. Grade: ≥98% by HPLC. CAS No. 149633-99-8. Molecular formula: C30H31NO9. Mole weight: 549.6.
JAG-1, scrambled
It is a scrambled sequence of JAG-1, and it is commonly used as a negative control. Synonyms: Arg-Cys-Gly-Pro-Asp-Cys-Phe-Asp-Asn-Tyr-Gly-Arg-Tyr-Lys-Tyr-Cys-Phe; Jagged-1, scrambled. Grade: ≥95%. CAS No. 402941-23-5. Molecular formula: C93H127N25O26S3. Mole weight: 2107.35.
JAG-1, scrambled TFA
JAG-1, scrambled TFA is a scrambled sequence of JAG-1 (188-204), and it is commonly used as a negative control. Synonyms: H-Arg-Cys-Gly-Pro-Asp-Cys-Phe-Asp-Asn-Tyr-Gly-Arg-Tyr-Lys-Tyr-Cys-Phe-OH.TFA; L-arginyl-L-cysteinyl-glycyl-L-prolyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-alpha-aspartyl-L-asparagyl-L-tyrosyl-glycyl-L-arginyl-L-tyrosyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-phenylalanine trifluoroacetic acid. Grade: ≥95%. Molecular formula: C95H128F3N25O28S3. Mole weight: 2221.37.
Jagged-1 (188-204)
Jagge-1 (188-204) is the Jagge-1 (JAG-1) protein fragment. JAG1, a Notch ligand, is highly expressed in cultured and primary multiple myeloma (MM) cells and induces the maturation of monocyte derived dendritic cells. Synonyms: L-Arginine, L-cysteinyl-L-α-aspartyl-L-α-aspartyl-L-tyrosyl-L-tyrosyl-L-tyrosylglycyl-L-phenylalanylglycyl-L-cysteinyl-L-asparaginyl-L-lysyl-L-phenylalanyl-L-cysteinyl-L-arginyl-L-prolyl-; JAG-1(188-204); Cys-Asp-Asp-Tyr-Tyr-Tyr-Gly-Phe-Gly-Cys-Asn-Lys-Phe-Cys-Arg-Pro-Arg. Grade: ≥95%. CAS No. 219127-21-6. Molecular formula: C93H127N25O26S3. Mole weight: 2107.35.
Jagged-1 (188-204)
Jagged-1 (188-204) is a fragment of the Jagged-1 (JAG-1) protein with Notch agonist activity. JAG-1 is a Notch ligand highly expressed in cultured and primary multiple myeloma (MM) cells. JAG-1 induces maturation of monocyte-derived human dendritic cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 219127-21-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1846.
Jagged-1 (188-204) TFA
Jagged-1 (188-204) TFA is a fragment of the Jagged-1 (JAG-1) protein with Notch agonist activity. JAG-1 is a Notch ligand that is highly expressed in cultured and primary multiple myeloma (MM) cells and can induce monocyte-derived human dendritic cells to mature. Synonyms: H-Cys-Asp-Asp-Tyr-Tyr-Tyr-Gly-Phe-Gly-Cys-Asn-Lys-Phe-Cys-Arg-Pro-Arg-OH.TFA; L-Cysteinyl-L-α-aspartyl-L-α-aspartyl-L-tyrosyl-L-tyrosyl-L-tyrosylglycyl-L-phenylalanylglycyl-L-cysteinyl-L-asparaginyl-L-lysyl-L-phenylalanyl-L-cysteinyl-L-arginyl-L-prolyl-L-arginine TFA salt; JAG 1 TFA salt; JAG 1 peptide TFA salt. Grade: ≥95%. Molecular formula: C95H128F3N25O28S3. Mole weight: 2221.42.
JAK1/2 ligand 1
JAK1/2 ligand 1 is the ligand of JAK1/2 and can be used for the synthesis of PROTACs, such as JAK1/2 Ligand-Linker Conjugates 1 (HY-179716)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1026028-96-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-179716.
JAK1-IN-13
JAK1-IN-13 (compound 36b) is an orally active, potent and highly selective inhibitor of JAK1 with an IC50 of 0.044 nM. JAK1-IN-13 significantly decreases STAT3 phosphorylation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2778330-90-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-161015.
JAK2-IN-7 is a selective JAK2 inhibitor with IC50s of 3, 11.7, and 41 nM for JAK2, SET-2, and Ba/F3V617F cells, respectively. JAK2-IN-7 possesses >14-fold selectivity over JAK1, JAK3, FLT3. JAK2-IN-7 stimulates cell cycle arrest in the G0/G1 phase and induces tumor cellapoptosis. Antitumor activities[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2593402-36-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131906.
JAK2 JH2 binder-1
JAK2 JH2 binder-1 (compound 11) is a potent and selective JAK2 JH2 binder, with a Kd of 37.1 nM. JAK2 JH2 binder-1 has the potential for various myeloproliferative neoplasms research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2923309-41-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-146186.
JAK2 JH2 Tracer
JAK2 JH2 Tracer (Tracer 5) is a fluorescent probe for JAK2 JH2 domain, with a Kd value of 0.2 μM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2101955-00-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-102055.
JAK2/TYK2-IN-1
JAK2/TYK2-IN-2 is a potent and selective TYK2 inhibitor with IC50 values of 9 and 157 nM for TYK2 and JAK2, respectively. JAK2/TYK2-IN-2 has anti-inflammatory activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2613434-12-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143884.
A cell-permeable phenyl-indolyl maleimide compound that acts as a potent, ATP-binding site targeting and reversible inhibitor of GSK-3b, JAK3, PKCa and PKCth (IC50=3, 8, 13 and 68nM, respectively) with excellent selectivity over 40-kinases, including JAK1, JAK2 and Tyk2 (IC50=1.017, 2.55 and 8.055uM, respectively). Shown to efficiently block interleukin stimulated STAT5 phosphorylation and T cell costimulation (IC50=0.525, 1.294 and 0.689uM in IL15-MO7, IL2-CTLL and TCR/CD28-Jurkat cells, respectively). Group: Biochemicals. Grades: Highly Purified. CAS No. 1260181-14-3. Pack Sizes: 5mg. Molecular Formula: C??H??F?N?O?, Molecular Weight: 526.5. US Biological Life Sciences.
A cell-permeable steroidal-purinethione that targets JAK3 kinase domain and selectively inhibits JAK3, but not JAK1, JAK2, or TYK2, activity and effectively blocks the constitutive Jak3 and STAT5 phosphorylations (complete inhibition at 10uM) in BaF3-JAK3V674A and BLNK-/- BKO84 culltures. Shown to prevent the JAK3-dependent survival of L540, BaF3-JAK3WT, BaF3-JAK3V674A, and BLNK-/- BKO84 cells (by 40%, 50%, 57%, and 85%, respectively; 20uM; 72 h), while exhibiting no effect against the JAK3-independent growth in DU145, HDLM-2, and MDA-MB-468 cultures. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
JAK-IN-20
JAK-IN-20 is a potent, pan and orally active JAK inhibitor with an IC50s of 7 nM, 5 nM, 14 nM for JAK1, JAK2, JAK3, respectively. JAK-IN-20 shows excellent pharmacokinetics and displays anti-inflammatory efficacy in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1654776-91-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-143444.
JAK-IN-5 hydrochloride
JAK-IN-5 hydrochloride is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2751323-21-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111471A.
JAK Inhibitor I
JAK Inhibitor I. Group: Biochemicals. Alternative Names: 2-(1,1-Dimethylethyl)-9-fluoro-3,6-dihydro-7H-benz[h]-imidaz[4,5-f]isoquinolin-7-one; DBI; Merck-5; Pyridone 6; DBI. Grades: Highly Purified. CAS No. 457081-03-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C18H16FN3O. US Biological Life Sciences.
Worldwide
JAK Inhibitor I (P6, DBI, (2-(1,1-Dimethylethyl)-9-fluoro-3,6-dihydro-7H-benz[h]-imidaz[4,5-f]isoquinolin-7-one, Pyridone 6, JAK1 Inhibitor I, JAK3 Inhibitor VII, JAK2 Inhibitor I)
A potent, reversible, cell-permeable, and ATP-competitive inhibitor of Janus protein tyrosine kinases (JAKs). Displays potent inhibitory activity against JAK1 (IC50=15nM for murine JAK1), JAK2 (IC50=1nM), JAK3 (Ki=5nM), and Tyk2 (IC50=1nM). Inhibits other kinases at much higher concentrations. Shown to inhibit IL2- and IL4-dependent proliferation of CTLL cells and block the phosphorylation of STAT5; and further induce growth inhibition of multiple myeloma cells expressing activated JAKs and STAT3, unlike AG 490. A 10mM solution of JAK Inhibitor I in DMSO is also available. Group: Biochemicals. Grades: Highly Purified. CAS No. 457081-03-7. Pack Sizes: 500ug, 1mg. US Biological Life Sciences.
Worldwide
JAK-STAT Compound Library
A unique collection of 256 JAK/STAT signaling targeted compounds for high throughput and high content screening; - Effective tool for studying the JAK/STAT targets; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L3700. Categories: JAK-STAT Compounds Libraries.
JalapeNo Pepper, Mesquite Smoked
JalapeNo Pepper, Mesquite Smoked. Group: Molecular Biology. Alternative Names: Chipotle Pepper. Grades: Molecular Biologist Grade. CAS No. Pack Sizes: 14g. US Biological Life Sciences.
Worldwide
Jalapinolic acid
Jalapinolic acid. Alternative Names: 11-Hydroxyhexadecanoic acid. CAS No. 502-75-0. Purity: >98.0%. Product ID: FFC-AR-502750. Molecular formula: C16H32O3. Mole weight: 272.42. IUPAC Name: 11-hydroxyhexadecanoic acid. Alfa Chemistry - ISO 9001:32057 Certified.
Jamaicin impurity 1
Jamaicin impurity 1. Uses: For analytical and research use. Molecular formula: C2113CH15D3O6. Mole weight: 382.39. Catalog: APB12290.
Janelia Fluor® 549 TFA
Janelia Fluor® 549 TFA (JF549 TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm[1]. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JF549 TFA. CAS No. 2245946-45-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-131022.
Janelia Fluor® 646, SE
Janelia Fluor 646, SE (JF646, SE) is a red fluorescent dye can be used in cellular imaging[1]. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JF646, SE; JF646, NHS. CAS No. 1811539-59-9. Pack Sizes: 1 mg; 2 mg; 5 mg; 10 mg. Product ID: HY-130735.
Janelia Fluor® 646, Tetrazine
Janelia Fluor 646, Tetrazine (JF646, Tetrazine) a red fluorescent dye that contains a tetrazine group. JF646, Tetrazine can be used in cellular imaging[1]. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JF646, Tetrazine. CAS No. 2042192-00-5. Pack Sizes: 200 μg; 500 μg; 1 mg. Product ID: HY-138659.
Janex 1
Janex 1. Group: Biochemicals. Alternative Names: 4-(4'-Hydroxyphenyl)amino-6,7-dimethoxyquinazoline; WHI-P 131. Grades: Highly Purified. CAS No. 202475-60-3. Pack Sizes: 5mg. Molecular Formula: C16H15N3O3, Molecular Weight: 297.31. US Biological Life Sciences.
Worldwide
JANEX-1
JANEX-1 (WHI-P131) is a potent and specific JAK3 inhibitor (estimated Ki=2.3 μM). JANEX-1 (WHI-P131) shows potent JAK3-inhibitory activity (IC50 of 78 μM), does not inhibit JAK1 and JAK2. Uses: Scientific research. Category: Signaling pathways. Alternative Names: WHI-P131; Jak3 inhibitor I. CAS No. 202475-60-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-15508.
Janthinocin A
It is produced by the strain of Janthinobacterium lividum. Janthinocin A has strong activity of anti-gram-positive bacteria and moderate anti-gram-negative bacteria, and has strong inhibitory effect on drug-resistant staphylococcus such as penicillin, tetracycline, erythromycin, methicillin and gentamicin. CAS No. 131086-52-7. Molecular formula: C57H84N12O16. Mole weight: 1193.34.
Janthinocin B
It is produced by the strain of Janthinobacterium lividum. Janthinocin B has strong activity of anti-gram-positive bacteria and moderate anti-gram-negative bacteria, and has strong inhibitory effect on drug-resistant staphylococcus such as penicillin, tetracycline, erythromycin, methicillin and gentamicin. Synonyms: 8-(alpha,beta-Didehydro-beta-hydroxytryptophan)janthinocin A; Janthinocin A, 8-(alpha,beta-didehydro-beta-hydroxytryptophan)-. CAS No. 131086-53-8. Molecular formula: C57H82N12O16. Mole weight: 1191.33.
Janthitrem B
It is a tremorgenic mycotoxin produced by the strain of Penicillium Janthinellum. Synonyms: 34-deoxy-34,35-didehydro-janthitrem E; (2R,3R,4bS,6aS,9S,9aR,15bS,15cR,17aS)-10,10,12,12,15b,15c-hexamethyl-2-(prop-1-en-2-yl)-2,3,5,6,6a,7,9,9a,10,12,15,15b,15c,16,17,17a-hexadecahydro-4bH-chromeno[5',6':6,7]indeno[1,2-b]pyrano[4',3':3,4]cyclopenta[1,2-f]indole-3,4b,9-triol; 4bH-Pyrano[2'',3'':5',6']benz[1',2':6,7]indeno[1,2-b]pyrano[4',3':3,4]cyclopent[1,2-f]indole-3,4b,9-triol,2,3,5,6,6a,7,9,9a,10,12,15,15b,15c,16,17,17a-hexadecahydro-10,10,12,12,15b,15c-hexamethyl-2-(1-methylethenyl)-, (2R,3R,4bS,6aS,9S,9aR,15bS,15cR,17aS)-. CAS No. 73561-90-7. Molecular formula: C37H47NO5. Mole weight: 585.77.
Metformin hydrochloride mixture with sitagliptin phosphate is an AMP-activated protein kinase stimulant. It is also a CD26 antigen inhibitor, Gluconeogenesis inhibitor, and Glucose modulator. Category: Active pharmaceutical ingredients. CAS No. 1011232-08-8. Product ID: API1011232088. Molecular formula: C20H30ClF6N10O5P. Mole weight: 670.93.
Janus green B
Janus green B. Group: Biochemicals. Grades: Highly Purified. CAS No. 2869-83-2. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C30H31ClN6. US Biological Life Sciences.
Worldwide
Janus Green B
Janus Green B. Uses: For analytical and research use. Alternative Names: 3-Diethylamino-7-(4-dimethylaminophenylazo)-5-phenylphenazinium chloride; Diazin Green S. CAS No. 2869-83-2. Molecular formula: C30H31ClN6. Mole weight: 511.06. Catalog: APB2869832.
Janus Green B Certified ≥60% (Dye content)
Janus Green B Certified ≥60% (Dye content). Group: Biochemicals. Grades: Certified Dye. Pack Sizes: 5g, 25g, 100g, 250g. US Biological Life Sciences.
Worldwide
Janus green B (C.I. 11050)
5g Pack Size. Group: Stains & Indicators. Formula: C30H31ClN6. CAS No. 2869-83-2. Prepack ID 58328236-5g. Molecular Weight 511.06. See USA prepack pricing.
Japonicin-1 is an antibacterial peptide isolated from Rana japonica (Japanese brown frog). It has activity against Gram-negative bacteria Escherichia coli and Gram-positive bacteria Staphylococcus aureus. Synonyms: Phe-Phe-Pro-Ile-Gly-Val-Phe-Cys-Lys-Ile-Phe-Lys-Thr-Cys. Grade: 95.4%. Molecular formula: C82H118N16O16S2. Mole weight: 1648.
Japonicin-1CDYa
Japonicin-1CDYa is an antibacterial peptide isolated from Rana dybowskii. It has activity against gram-negative bacteria and gram-positive bacteria. Synonyms: Phe-Phe-Pro-Leu-Ala-Leu-Leu-Cys-Lys-Val-Phe-Lys-Lys-Cys. Molecular formula: C82H127N17O15S2. Mole weight: 1655.15.
Japonicin-1Npa
Japonicin-1Npa is an antibacterial peptide isolated from Nanorana parkeri. Synonyms: Phe-Leu-Leu-Phe-Pro-Leu-Met-Cys-Lys-Ile-Gln-Gly-Lys-Cys. Grade: 97.3%.
Japonicin-1Npb
Japonicin-1Npb is an antibacterial peptide isolated from Nanorana parkeri. Synonyms: Phe-Val-Leu-Pro-Leu-Val-Met-Cys-Lys-Ile-Leu-Arg-Lys-Cys. Grade: 95.8%.
Japonicin-2
Japonicin-2 is an antibacterial peptide isolated from Rana japonica (Japanese brown frog). It has activity against Gram-negative bacteria Escherichia coli and Gram-positive bacteria Staphylococcus aureus. Synonyms: Phe-Gly-Leu-Pro-Met-Leu-Ser-Ile-Leu-Pro-Lys-Ala-Leu-Cys-Ile-Leu-Leu-Lys-Arg-Lys-Cys. Grade: 95.6%. Molecular formula: C110H191N27O23S3. Mole weight: 2356.
jararhagin
Hemorrhagic endopeptidase from the venom of the jararaca snake (Bothrops jararaca). The 52-kDa enzyme contains a disintegrin domain. In peptidase family M12 (astacin family). Group: Enzymes. Synonyms: HF2-proteinase; JF1. Enzyme Commission Number: EC 3.4.24.73. CAS No. 160477-79-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4357; jararhagin; EC 3.4.24.73; 160477-79-2; HF2-proteinase; JF1. Cat No: EXWM-4357.