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| Product | Description | |
|---|---|---|
| M1001 | M1001 Inhibitor. Uses: Scientific use. Product Category: T7802. CAS No. 874590-32-6. |  |
| M-110 | M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases with a preference for PIM-3 (IC50=47 nM). M-110 inhibits PIM-1 and PIM-2 with similar IC50s of 2.5 μM. M-110 inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1395048-49-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12830. |  |
| M1145 | M1145, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 shows more than 90-fold higher affinity for GAL2 over GAL1 (Ki=587 nM) and a 76-fold higher affinity over GalR3 (Ki=497 nM). M1145 has an additive effect on the signal transduction of galanin[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1172089-00-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1135. | |
| M 1145 | M 1145. Group: Biochemicals. Grades: Purified. CAS No. 1172089-00-7. Pack Sizes: 500ug. US Biological Life Sciences. |  Worldwide |
| M-13-1 | It is an anthracycline antibiotic derived from Nocardia brasiliensis IFM-0075. Alternative Names: 4,11-Dihydroxy-2,8-dimethyl-7-methoxynaphthacene-5,12-dione. Molecular formula: C21H16O5. Mole weight: 348.35. |  |
| M190S | M109S is a novel small molecule protecting cells from mitochondria-dependent apoptosis both in vitro and in vivo. M109S has the potential to become a research tool for studying cell death mechanisms and to develop therapeutics targeting mitochondria-dependent cell death pathway. M109S has orally bioactivity with excellent brain permeability[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2578300-07-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156168. | |
| m1-Nitrodienamine | m1-Nitrodienamine. CAS No. 113418-72-7. Purity: 95% (TLC, NMR, IR). Product ID: ACM113418727. Molecular formula: C12H20N2O2. Mole weight: 224 Da. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| M-230B | M-230B is originally isolated from Myxococcus xanthus M516E. It has anti-gram-negative and weak anti-gram-positive activity. Molecular formula: C35H59NO8. Mole weight: 621.84. | |
| M 24 | M 24 is the first selective AT2 receptor agonist (Ki 0.4nM and 10.000 nM for AT2 and AT1 respectively). M 24 effects against endothelial inflammation and leukocyte adhesion both in vitro and in vivo. Alternative Names: M 24; M24; M-24; butyl N-[3-[4-(imidazol-1-ylmethyl)phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylcarbamate. Grades: 98%. CAS No. 477775-14-7. Molecular formula: C23H29N3O4S2. Mole weight: 475.62. | |
| M-2420 | M-2420 is a fluorescent substrate for β-secretase sites containing Swedish mutations in amyloid precursor protein (APP). Alternative Names: Methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl. Grades: ≥95%. CAS No. 310427-95-3. Molecular formula: C70H91N15O27. Mole weight: 1574.56. | |
| M 25 | M 25. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| M2698 | M2698 (MSC2363318A) is an orally active, ATP competitive, selective p70S6K and Akt dual-inhibitor with IC50s of 1 nM for p70S6K, Akt1 and Akt3. M2698 can cross the blood-brain barrier and has anti-cancer activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MSC2363318A. CAS No. 1379545-95-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100501. | |
| m27,3'-OGP3G (ARCA Cap Analog) | m27,3'-OGP3G (ARCA Cap Analog), renowned for its exceptional properties, is a cap analog. Its omnipresence is felt in various research arenas, permeating the realms of mRNA structure investigation, protein interactions exploration and viral replication mechanism elucidation. Alternative Names: mG(5')ppp(5')G; P-(5'-(3'-O-methyl)-7-methyl-guanosyl), P-(5'-(guanosyl))triphosphate; Guanosine 5'-(tetrahydrogen triphosphate), 7-methyl-3'-O-methyl-, inner salt, P''→5'-ester with guanosine; 3'-O-Methyl-m7GpppG; ARCA; ARCA (anti-reverse cap analog); m27,3'OGpppG; N7-Methyl-3'-O-Methyl-Guanosine-5'-Triphosphate-5'-Guanosine. Grades: ≥95% by HPLC. CAS No. 400806-46-4. Molecular formula: C22H31N10O18P3. Mole weight: 816.46. | |
| M300 Tool Steel Powder | M300 is an age hardenable martensitic tool steel with exceptional mechanical properties, specifically a high tensile strength and hardness. It is easily heat treated with superior mechanical properties being achieved after age hardening. |  |
| M-31850 | M-31850 is a potent, selective and competitive β-hexosaminidase (Hex) inhibitor with IC50s of 6.0 μM and 3.1 μM for human HexA and human HexB, respectively. M-31850 also competitively inhibits β-N-acetyl-D-hexosaminidase OfHex2 with a Ki of 2.5 μM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 281224-40-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104050. | |
| m32.2.7GP3G (Trimethylated Cap Analog) | m32.2.7GP3G (Trimethylated Cap Analog) is an indispensable compound of paramount significance, meticulously employed for the purpose of synthesizing mRNA molecules. By judiciously interweaving this cap analog within the process of mRNA transcription, it bestows a marked amplification in translational efficiency, stability and the intricate realm of translation initiation. Alternative Names: G(5')ppp(5')G; P; -(5'-2,2,7-trimethyl-guanosyl) P; -(5'-(guanosyl))triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 123212-20-4. Molecular formula: C23H33N10O18P3(free acid). Mole weight: 830.49 (free acid). | |
| M3258 | M3258 is an orally bioavailable, potent, reversible and highly selective immunoproteasome subunit LMP7 (β5i) inhibitor. M3258 exerts high biochemical (IC50=3.6 nM) and cellular (IC50=3.4 nM) potency against the LMP7 subunit. M3258 shows strong antitumor efficacy in multiple myeloma xenograft models. M3258 leads to a significant and prolonged suppression of tumor LMP7 activity and ubiquitinated protein turnover and the induction of apoptosis in multiple myeloma cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2285330-15-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111790. | |
| M344 | M344 (D 237) is an inhibitor of histone deacetylase (IC50=100 nM) and an inducer of terminal cell fifferentiation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D 237; MS 344. CAS No. 251456-60-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13506. | |
| M344 | M344 is a potent HDAC inhibitor, which can also induce expression of the pro-apoptotic genes, Puma and Bax, together with the morphological features of apoptosis, in MCF-7 cells. Alternative Names: M 344; M-344; Histone Deacetylase Inhibitor III. Grades: >98%. CAS No. 251456-60-7. Molecular formula: C16H25N3O3. Mole weight: 307.39. | |
| M344 | An amide analog of Trichostatin A that potently Inhibits histone deacetylases (IC50 = 40 nM for rat liver HDAC and IC50 = 100 nM for maize HDAC). Induces differentiation and inhibits proliferation (~2uM) of murine erythroleukemia cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 251456-60-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| M 344 | M 344. Group: Biochemicals. Grades: Purified. CAS No. 251456-60-7. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| M351-0056 | M351-0056 is the agonist for the immune checkpoint protein VISTA, that reduces the secretion of VISTA-induced cytokines, promotes the T-cell proliferation induced by VISTA, and exhibits immunomodulatory activity. M351-0056 ameliorates Imiquimod (HY-B0180)-induced psoriatic dermatitis in mouse models[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1189495-81-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169853. | |
| M3541 | M3541 is a potent, ATP-competitive and selective ATM inhibitor with an IC50 of 0.25 nM. M3541 shows remarkable selectivity against other protein kinases. M3541 suppresses double-strand breaks (DSB) repair and has antitumor activities[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1360628-91-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-160096. | |
| m-3M3FBS | m-3M3FBS. Group: Biochemicals. Grades: Purified. CAS No. 200933-14-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| m-3M3FBS | m-3M3FBS is a potent phospholipase C (PLC) activator. m-3M3FBS stimulates superoxide generation in human neutrophils, upregulates intracellular calcium concentration, and stimulates inositol phosphate generation in various cell lines. m-3M3FBS induces monocytic leukemia cell apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 200933-14-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19619. | |
| M3N2 (Man-3) Glycan, 2-AA labelled | M3N2 (Man-3) Glycan, 2-AA labelled is a biologically significant oligosaccharide mainly used in biomedical research. It's frequently applied in glycan profiling for diagnostics and therapeutic applications, particularly in cancer and inflammatory disease studies. Alternative Names: M3N2 N-linked oligosaccharide; Trimannosyl core; Trimannosyl chitobiose. | |
| M40 | M40. Group: Biochemicals. Grades: Purified. CAS No. 143896-17-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| M40 | M40 is a potent, non-selective antagonist of galanin receptor, and has no effect on chow or fat intake. Alternative Names: M 40; M-40; H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2; L-Alaninamide, glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-; Glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-alaninamide; M 40 (peptide). Grades: ≥95%. CAS No. 143896-17-7. Molecular formula: C95H146N22O24. Mole weight: 1980.31. | |
| M40 acetate | M40 acetate is a potent, non-selective antagonist of galanin receptor, and has no effect on chow or fat intake. Alternative Names: H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2.CH3CO2H; glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparagyl-L-seryl-L-alanyl-glycyl-L-tyrosyl-L-leucyl-L-leucyl-glycyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-alaninamide acetic acid; M 40 acetate. Grades: ≥95%. Molecular formula: C96H149N23O26. Mole weight: 2041.38. | |
| M435-1279 | M435-1279 is a UBE2T inhibitor. M435-1279 inhibits the Wnt/β-catenin signaling pathway hyperactivation through blocking UBE2T-mediated degradation of RACK1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1359431-16-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141891. | |
| M-4365 A1 | It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 A1 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics. Molecular formula: C31H53NO8. Mole weight: 567.75. | |
| M-4365 G1 | It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 G1 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics. And it also has a certain anti-Gram-negative bacteria activity. Molecular formula: C31H53NO7. Mole weight: 551.75. | |
| M-4365 G2 | It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 G2 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics. Alternative Names: SCHEMBL192993. Molecular formula: C31H51NO8. Mole weight: 565.74. | |
| M443 | M443 is an irreversible and specific inhibitor of MRK, with an IC50<125 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1820684-31-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112274. | |
| M47 | M47 is a molecular glue that selectively destabilizes Cryptochrome 1 (CRY1) and increases degradation of the CRY1 in the nucleus. M47 enhances apoptosis in Ras-transformed P53-deficient mouse skin fibroblast lines and enhances life span in p53 knockout mice. M47 can be used in research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 890808-56-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148764. | |
| M4K-2009 | M4K-2009 is an orally bioactive ALK2 inhibitor with an IC50 of 13 nM. M4K-2009 exerts comparable inhibitory potency against wild-type and mutant ALK2G328V, ALK2R206H, and ALK2R258G. M4K-2009 exhibits moderate off-target inhibitory activity against hERG potassium channels. M4K-2009 can be used in studies related to diffuse intrinsic pontine glioma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2600795-07-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149591. | |
| M4K2163 dihydrochloride | M4K2163 dihydrochloride is a potent, selective, blood-brain barrier (BBB) permeable activin receptor-like kinase-2 (ALK2) inhibitor, with an IC50 of 19 nM. M4K2163 dihydrochloride can be used in the research of diffuse intrinsic pontine glioma (DIPG)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2863635-04-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155939. | |
| M4K2234 | M4K2234, a chemical probe, is an orally active, highly selective inhibitor of ALK1 and ALK2 with IC50 values of 7 nM and 14 nM, respectively. M4K2234 specifically blocks BMP signaling by inhibiting the phosphorylation of SMAD1/5/8. M4K2234 inhibits BMP7-stimulated reporter gene activity (IC50 = 16 nM). M4K2234 can be used for the investigation of ALK1/2-mediated biological processes and related diseases such as diffuse midline glioma (DMG) and fibrodysplasia ossificans progressiva (FOP)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2421141-51-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148234. | |
| M5N36 | M5N36 is a potent and selective Cdc25C inhibitor with IC50 values of 0.15, 0.19, 0.06 μM for Cdc25A, Cdc25B, Cdc25C, respectively. M5N36 shows anti-proliferative activity and increases the expression of p-CDK1 and p-CDK2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2832887-40-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132578. | |
| M617 | M617. Group: Biochemicals. Grades: Purified. CAS No. 860790-38-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| M617 | M617 is a selective galanin receptor 1 (GAL1) agonist, with Kis of 0.23 and 5.71 nM for GAL1 and GAL2, respectively. M617, acting through its central GAL1, can promote GLUT4 expression and enhance GLUT4 content in the cardiac muscle of type 2 diabetic rats[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 860790-38-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1131. | |
| M65 | M65 is a potent and specific antagonist of PAC1 receptor. Alternative Names: PAC1 Receptor Antagonist M65; H-Cys-Asp-Ala-Thr-Cys-Gln-Phe-Arg-Lys-Ala-Ile-Asp-Asp-Cys-Gln-Lys-Gln-Ala-His-His-Ser-Asn-Val-Pro-Gly-Asn-Ser-Val-Phe-Lys-Glu-Cys-Met-Lys-Gln-Lys-Lys-Lys-Glu-Phe-Lys-Ala-NH2 (Disulfide bridge: Cys1-Cys5, Cys14-Cys32). Grades: ≥95%. CAS No. 1872440-65-7. Molecular formula: C205H326N64O61S5. Mole weight: 4823.57. | |
| M6766 | M6766 is a selective endoplasmic reticulum oxidoreductase 1α (ERO1α) inhibitor with an IC50 of 1.4 μM and a KD of 1.1 μM. M6766 also inhibits ERO1β with an IC50 of 7.2 μM. M6766 binds to the flavin adenine dinucleotide-binding pocket in ERO1α. M6766 inhibits granule secretion, αIIbβ3 integrin activation, Ca2+ mobilization, and platelet aggregation. M6766 can be used for the research of neurological disease, such as ischemic stroke[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 696628-90-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-175593. | |
| M68(Cetearyl Glucoside & Cetearyl Alcohol) | M68(Cetearyl Glucoside & Cetearyl Alcohol). CAS No. 246159-33-1. Product ID: CI-GU-0251. Alfa Chemistry - ISO 9001:32057 Certified. | |
| M700F048 | M700F048 is a major plant metabolite of fungicide Fluxapyroxad[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2056235-51-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-111741. | |
| M701 | M701 is a T-cell engager bispecific humanized antibody targeting epithelial cell adhesion molecule (EpCAM) and cluster of differentiation 3 (CD3). M701 binds to EpCAM on tumor cells and CD3 on T cells, thereby linking the two cell populations to achieve targeted cytotoxicity and T cell-mediated cytotoxicity. M701 is applicable to research related to advanced epithelial solid tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2933295-42-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991526. | |
| m7(3'OMeG)(5')pp-1-imidazol | m7(3'OMeG)(5')pp-1-imidazol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 2089461-53-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-172307. | |
| m7(3'OMeG)(5')ppp(5')(2'OMeA)pG ammonium salt | Used for in vitro transcription of 5'-capped mRNA to produce a Cap 1 structure. EZ Cap reagent AG 3'OMe should be used with the specific starting sequence 5'AG 3'. Alternative Names: (3'-OMe-m7G)(5')ppp(5')(2'-OMeA)pG ammonium salt; 3'Ome-m7GpppAmpG ammonium salt; Guanosine, 7-methyl-3'-O-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt, ammonium salt; m7(3'OMeG)(5')ppp(5')(2'OMeA)pG ammonium salt; CAP GAG (3'OMe) ammonium salt. Grades: ≥97% by HPLC. Molecular formula: C33H45N15O24P4 (free acid). Mole weight: 1159.71 (free acid). | |
| m7(3'OMeG)(5')ppp(5')(2'OMeG)pG | EZ Cap Reagent GG (3'OMe) is a co-transcription capping reagent. Alternative Names: EZ Cap Reagent GG (3' OMe) for co-transcriptional capping of mRNA; EZ Cap Reagent GG (3' OMe); GGG(3'OMe); m7(3'OMeG)ppp(2'OMeG)pG. Grades: ≥95% by AX-HPLC. CAS No. 2089461-54-9. Molecular formula: C33H45N15O25P4. Mole weight: 1175.69. | |
| m7-3'OMe-GDP | A 5'cap analog used for co-transcriptional capping of mRNA. Alternative Names: m7-3'-OMe-GDP. Molecular formula: C12H19N5O11P2 (free acid). Mole weight: 471.25 (free acid). | |
| M7594_0037 | M7594_0037 is a potent inhibitor of human peptide deformylase (HsPDF) that has anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 774551-07-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-122097. | |
| m7G(5')ppp(5')(2'OMeA)pG | Used for in vitro transcription of 5'-capped mRNA to produce a Cap 1 structure. Compared with the Cap 0 structure, the mRNA with Cap 1 structure is more suitable for the mammalian system and has a higher transcription efficiency. Alternative Names: EZ Cap™ Reagent AG [m7G(5')ppp(5')(2'OMeA)pG]. Grades: ≥95% by AX-HPLC. Molecular formula: C32H43N15O24P4 (free acid). Mole weight: 1145.68 (free acid). | |
| m7G(5')ppp(5')(2'OMeA)pU | A 5'cap analog used for co-transcriptional capping of mRNA. The product is specifically designed for self-replicating RNAs based on the genomes of positive sense strand RNA viruses such as Venezuelan equine encephalitis virus (VEEV), Semliki forest virus (SFV), and Sindbis virus (SIN). Alternative Names: Uridine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt; (m7)Gppp(5')(m2'O)ApU; m7G(5')ppp(5')(2'-OMeA)pU; m7Gppp(5')A2'OMepU; m7GpppAmpU trinucleotide cap; GAU. Grades: ≥95% by HPLC. CAS No. 2734858-38-7. Molecular formula: C31H42N12O25P4. Mole weight: 1106.63. | |
| m7G(5')ppp(5')(2'OMe,m6A)pG | m7G(5')ppp(5')(2'OMe,m6A)pG is a trinucleotide mRNA 5' cap analogs. m7G(5')ppp(5')(2'OMe,m6A)pG can be used for RNA synthesis in vitro. Alternative Names: Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-N-methyl-2'-O-methylguanylyl-(3'→5')-, inner salt; Adenosine 5'-(tetrahydrogen triphosphate), guanylyl-(5'→3')-N-methyl-2'-O-methyl-, P''→5'-ester with 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purinium, inner salt; CAP GAG(m6A) m7G(5')ppp(5')(2'OMe,m6A)pG; GAG(m6A); m7Gppp(2'OMe,m6A)pG; m7Gpppm6AmpG. Grades: ≥98%. CAS No. 71340-22-2. Molecular formula: C33H45N15O24P4. Mole weight: 1159.69. | |
| m7G(5')ppp(5')(2'OMe,m6A)pG ammonium salt | m7G(5')ppp(5')(2'OMe,m6A)pG ammonium salt is a trinucleotide mRNA 5' cap analogs. m7G(5')ppp(5')(2'OMe,m6A)pG ammonium salt can be used for RNA synthesis in vitro. Alternative Names: CAP GAG(m6A) m7G(5')ppp(5')(2'OMe,m6A)pG Ammonium; GAG(m6A) ammonium salt; m7Gppp(2'OMe,m6A)pG ammonium salt; m7Gpppm6AmpG ammonium salt. Grades: ≥98%. Molecular formula: C33H45N15O24P4 (free acid). Mole weight: 1159.69 (free acid). | |
| m7GDP | m7GDP is an esteemed compound commodity widely employed within the biomedical realm, epitomizes an indispensable medium in sundry enzymatic reactions, exerting a momentous influence on the intricate processes of RNA transcription and translation. Its invaluable utility extends to the research of viral afflictions, notably influenza and respiratory syncytial virus (RSV). Additionally, it facilitates meticulous investigations pertaining to mRNA processing and the cap-dependent translation mechanism. Alternative Names: 7-methyl-7,8-dihydroguanosine-5'-diphosphate; 7-methylguanosine diphosphate; N7-methyl-GDP; 7-Methyl-Guanosine-5'-Diphosphate; 1H-Purinium, 2-amino-6,9-dihydro-9-[5-O-[hydroxy(phosphonooxy)phosphinyl]-β-D-ribofuranosyl]-7-methyl-6-oxo-; 7-Methylguanosine 5'-(trihydrogen diphosphate); 7-Methyl-GDP; 7-Methylguanosine 5'-diphosphate; 7-methylguanosine 5'-diphosphate(1+); N7-methylguanosine 5'-diphosphate. Grades: 95%. CAS No. 117723-13-4. Molecular formula: C11H18N5O11P2. Mole weight: 458.24. | |
| m7GMP | m7GMP, the eminent molecule widely employed in the biomedical sphere, holds paramount importance in the production of mRNA and viral RNA. Its indispensable contribution lies within the realm of cap-dependent translation initiation, where it assumes a distinctive stance as the prime target for recognition by the initiation factor eIF4E. Wholly engrossed in the intricate domains of RNA modification and processing, m7GMP exhibits vast prospects for the research of RNA-associated afflictions, including the notorious cancer and pernicious viral infections. Alternative Names: 7-methyl-guanosine-5'-monophosphate, triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 47442-17-1. Molecular formula: C11H16N5O8P (free acid). Mole weight: 377.25 (free acid). | |
| m7GMP-α-F | m7GMP-α-F is an esteemed bioactive nucleotide analog extensively employed, unveiling its true compound as a formidable antagonist of RNA polymerase. Moreover, the scientific community harnesses the power of m7GMP-α-F for intricate studies pertaining to gene expression regulation and the labyrinthine world of RNA processing. Alternative Names: (m7GpF); 7-methyl-guanosine-5'-(α-fluoro)-monophosphate; 7-methyl-guanosine-5'-(1-fluoro)-monophosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C11H16FN5O7P. Mole weight: 380.25. | |
| m7G(N-biotin)pppG | m7G(N-biotin)pppG is an amino- and carboxy-functionalized dinucleotide 5' cap analog that is suitable for labeling with biotin or fluorescent tags by the employment of an in situ NHS activation strategy. Alternative Names: P1-(2'-aminobiotinyl-2'-deoxy-N7-methylguanosin-5'-yl) P3-(guanosin-5'-yl) triphosphate. Molecular formula: C31H41N13O19P3S3 (free base). Mole weight: 1024.72 (free base). | |
| m7GNpppG | m7GNpppG is an amino- and carboxy-functionalized dinucleotide 5' cap analog that is suitable for labeling with biotin or fluorescent tags by the employment of an in situ NHS activation strategy. Alternative Names: P1-(2'-amino-2'-deoxy-N7-methylguanosin-5'-yl) P3-(guanosin-5'-yl) triphosphate. Molecular formula: C21H27N11O17P33 (free base). Mole weight: 798.43 (free base). | |
| m7GP3C | m7GP3C is a cutting-edge compound developed for studying the metastatic stage of breast cancer. Its mechanism of action involves the potent inhibition of DNA topoisomerase II, thereby impeding DNA replication and effectively inducing the eradication of malignant cells. Alternative Names: P; -(5'-7-methyl-guanosyl) P; -(5'-(cytidyl))triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 70441-86-0. Molecular formula: C20H29N8O18P3(free acid). Mole weight: 762.41 (free acid). | |
| m7GP3G (Monomethylated Cap Analog) | m7GP3G (Monomethylated Cap Analog) is an indispensable compound extensively employed, supporting the synthesis of mRNAs possessing altered RNA cap structures. This remarkable compound assumes a pivotal function in advancing studies pertaining to gene expression and mRNA processing, particularly in the progressive frontiers of RNA vaccines and mRNA therapeutics. By enabling investigation into cap-dependent translation mechanisms, as well as facilitating the evaluation of mRNA stability and translational efficiency, this product fosters an unprecedented comprehension of intricate cellular processes. Alternative Names: Guanosine 5'-(tetrahydrogen triphosphate), P''→5'-ester with 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purinium inner salt; m7Gp3G; m7GpppG; mG(5')ppp(5')G; P1-(5'-7-methyl-guanosyl) P3-(5'-(guanosyl))triphosphate; mCAP; m7G(5')ppp(5')G Cap Analog; N7-Methyl-Guanosine-5'-Triphosphate-5'-Guanosine; 7-Methyl-guanosine-5'-triphosphate-5'-guanosine; M7-GpppG. Grades: ≥95% by HPLC. CAS No. 62828-64-2. Molecular formula: C21H29N10O18P3. Mole weight: 802.43. | |
| m7GP3G (Monomethylated Cap Analog) sodium salt | m7GP3G (Monomethylated Cap Analog) sodium salt is a vital product in the biomedical industry used for studying mRNA capping and translation initiation. It serves as a crucial tool for investigating RNA transcription, translation processes and mRNA stability. By mimicking the natural RNA cap structure, m7GP3G sodium salt aids in understanding diseases like cancer and viral infections, ultimately enabling the development of effective researchs. Alternative Names: m7G(5')ppp(5')G Sodium salt; P1-(5'-7-methyl-guanosyl) P3-(5'-(guanosyl))triphosphate, sodium salt; M7-GpppG sodium salt; Guanosine 5'-(tetrahydrogen triphosphate), P''→5'-ester with 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purinium inner salt, sodium salt; m7Gp3G sodium salt; m7GpppG sodium salt; mCAP sodium salt. Grades: ≥95% by HPLC. Molecular formula: C21H29N10O18P3 (free acid). Mole weight: 802.43 (free acid). | |
| m7GP5G | m7GP5G is a synthetic molecule used as a research tool in the biomedical industry to study various cellular processes, including DNA repair and transcription regulation. It has also shown potential in cancer treatment due to its ability to inhibit the activity of certain oncogenes. Clinical trials are ongoing to investigate its efficacy in treating breast, lung, and prostate cancers. Alternative Names: P; -(5'-7-Methyl-Guanosyl)-P; -(5'-Guanosyl)-pentaphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C21H32N10O24P5(free acid). Mole weight: 963.40 (free acid). | |
| m7GpppAmpG | m7GpppAmpG is a trinucleotide 5' cap analog with the capping efficiencies for the obtained RNAs of 90%. It is used to transcribe 5'cap mRNA in vitro to produce the Cap 1 structure, which is more suitable for mammalian systems and has higher transcriptional efficiency than the Cap 0 structure. m7GpppAmpG Cap Analog is a co-transcriptional capping agent that transcribes 5' capped mRNA in vitro to form the Cap 1 structure. Alternative Names: m7G(5')ppp(5')(2'-OMeA)pG; GAG; Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt; Adenosine 5'-(tetrahydrogen triphosphate), guanylyl-(5'→3')-2'-O-methyl-, P''→5'-ester with 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purinium inner salt; m7GpppA2'OmepG. Grades: ≥95% by HPLC. CAS No. 62858-30-4. Molecular formula: C32H43N15O24P4. Mole weight: 1145.67. | |
| m7GpppAmpG ammonium solution (100 mM) | m7GpppAmpG ammonium (m7G(5')ppp(5')(2'OMeA)pG ammonium) is a trinucleotide 5 end cap analog. m7GpppAmpG ammonium binds to eIF4E with a KD value of 45.6 nM. m7GpppAmpG ammonium caps RNA with a capping efficiency of 90%. m7GpppAmpG ammonium enhances mRNA stability and translation efficiency. m7GpppAmpG ammonium is used in mRNA therapeutic research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: m7G(5')ppp(5')(2'OMeA)pG ammonium. CAS No. 3080642-79-8. Pack Sizes: 20 μL; 50 μL; 100 μL; 200 μL. Product ID: HY-145974A. | |
| m7GpppGmpG | m7GpppGmpG is a trinucleotide 5 cap analog with the capping efficiencies for the obtained RNAs of 86%. Alternative Names: EZ Cap Reagent GG; EZ Cap Reagent GG for co-transcriptional capping of mRNA; m7G(5')ppp(5')(2'OMeG)pG; Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methylguanylyl-(3'→5')-, inner salt; m7Gppp(2'OMeG)pG; CAP GGG m7G(5')ppp(5')(2'OMeG)pG; GGG. Grades: ≥98%. CAS No. 1258049-00-1. Molecular formula: C32H43N15O25P4. Mole weight: 1161.66. | |
| m7GpppUpG | m7GpppUpG, an oligonucleotide, is an M 7 GpppNpG trinucleotide cap analogue. m7GpppUpG can be used as a chemical tool enabling manufacturing of RNA featuring either cap 0 or cap 1 structures. CAS No. 2638447-85-3. Molecular formula: C30H40N12O26P4. Mole weight: 1108.6. | |
| m7GTP-γ-aminophenyl-PEG4-Biotin | m7GTP-γ-aminophenyl-PEG4-Biotin is a groundbreaking theoretical compound used in unraveling the intricate intricacies of mRNA capping and RNA processing. Alternative Names: 7-Methylguanosine-5'-[γ-(4-aminophenyl)-PEG4]-5'-triphosphate-Biotin. Grades: ≥ 95 % by HPLC. Molecular formula: C38H58N9O21P3S (free acid). Mole weight: 1101.27 (free acid). | |
| m7GTP-γ-aminophenyl-PEG4- Cy5 | m7GTP-γ-aminophenyl-PEG4- Cy5 is a vital tool, commonly used for synthesizing fluorescent oligonucleotides. This product aids in the study of RNA and mRNA localization, structure and function within cells. It facilitates the detection and imaging of RNA molecules, providing valuable insights into gene expression, RNA processing and RNA-protein interactions. This versatile tool greatly contributes to advancing molecular biology research and drug discovery aimed at targeting RNA-related diseases. Alternative Names: 7-Methylguanosine-5'-[γ-(4-aminophenyl)-PEG; ]-5'-triphosphate - Cy5, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C61H82N9O26P3S2(free acid). Mole weight: 1513.40 (free acid). | |
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