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| Product | Description | |
|---|---|---|
| M1001 | M1001 Inhibitor. Uses: Scientific use. Product Category: T7802. CAS No. 874590-32-6. |  |
| M-110 | M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases with a preference for PIM-3 (IC50=47 nM). M-110 inhibits PIM-1 and PIM-2 with similar IC50s of 2.5 μM. M-110 inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1395048-49-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12830. |  |
| M1145 | M1145, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 shows more than 90-fold higher affinity for GAL2 over GAL1 (Ki=587 nM) and a 76-fold higher affinity over GalR3 (Ki=497 nM). M1145 has an additive effect on the signal transduction of galanin[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1172089-00-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1135. | |
| M 1145 | M 1145. Group: Biochemicals. Grades: Purified. CAS No. 1172089-00-7. Pack Sizes: 500ug. US Biological Life Sciences. |  Worldwide |
| M-13-1 | It is an anthracycline antibiotic derived from Nocardia brasiliensis IFM-0075. Synonyms: 4,11-Dihydroxy-2,8-dimethyl-7-methoxynaphthacene-5,12-dione. Molecular formula: C21H16O5. Mole weight: 348.35. |  |
| M190S | M109S is a novel small molecule protecting cells from mitochondria-dependent apoptosis both in vitro and in vivo. M109S has the potential to become a research tool for studying cell death mechanisms and to develop therapeutics targeting mitochondria-dependent cell death pathway. M109S has orally bioactivity with excellent brain permeability[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2578300-07-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156168. | |
| m1-Nitrodienamine | m1-Nitrodienamine. CAS No. 113418-72-7. Purity: 95% (TLC, NMR, IR). Product ID: ACM113418727. Molecular formula: C12H20N2O2. Mole weight: 224 Da. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| M-230B | M-230B is originally isolated from Myxococcus xanthus M516E. It has anti-gram-negative and weak anti-gram-positive activity. Molecular formula: C35H59NO8. Mole weight: 621.84. | |
| M-2420 | M-2420 is a fluorescent substrate for β-secretase sites containing Swedish mutations in amyloid precursor protein (APP). Synonyms: Methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl. Grade: ≥95%. CAS No. 310427-95-3. Molecular formula: C70H91N15O27. Mole weight: 1574.56. | |
| M 25 | M 25. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| M2698 | M2698 (MSC2363318A) is an orally active, ATP competitive, selective p70S6K and Akt dual-inhibitor with IC50s of 1 nM for p70S6K, Akt1 and Akt3. M2698 can cross the blood-brain barrier and has anti-cancer activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MSC2363318A. CAS No. 1379545-95-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100501. | |
| M2-Nitrodienamine | Nitrodienamine is an inhibitor of Ca2+/Mg2+ ATPase. Grade: 95% (NMR). Molecular formula: C14H24N2O2. Mole weight: 252.32. | |
| M300 Tool Steel Powder | M300 is an age hardenable martensitic tool steel with exceptional mechanical properties, specifically a high tensile strength and hardness. It is easily heat treated with superior mechanical properties being achieved after age hardening. |  |
| M-31850 | M-31850 is a potent, selective and competitive β-hexosaminidase (Hex) inhibitor with IC50s of 6.0 μM and 3.1 μM for human HexA and human HexB, respectively. M-31850 also competitively inhibits β-N-acetyl-D-hexosaminidase OfHex2 with a Ki of 2.5 μM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 281224-40-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104050. | |
| m32.2.7GP3G (Trimethylated Cap Analog) | m32.2.7GP3G (Trimethylated Cap Analog) is an indispensable compound of paramount significance, meticulously employed for the purpose of synthesizing mRNA molecules. By judiciously interweaving this cap analog within the process of mRNA transcription, it bestows a marked amplification in translational efficiency, stability and the intricate realm of translation initiation. Synonyms: G(5')ppp(5')G; P; -(5'-2,2,7-trimethyl-guanosyl) P; -(5'-(guanosyl))triphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. CAS No. 123212-20-4. Molecular formula: C23H33N10O18P3(free acid). Mole weight: 830.49 (free acid). | |
| M3258 | M3258 is an orally bioavailable, potent, reversible and highly selective immunoproteasome subunit LMP7 (β5i) inhibitor. M3258 exerts high biochemical (IC50=3.6 nM) and cellular (IC50=3.4 nM) potency against the LMP7 subunit. M3258 shows strong antitumor efficacy in multiple myeloma xenograft models. M3258 leads to a significant and prolonged suppression of tumor LMP7 activity and ubiquitinated protein turnover and the induction of apoptosis in multiple myeloma cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2285330-15-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111790. | |
| M344 | An amide analog of Trichostatin A that potently Inhibits histone deacetylases (IC50 = 40 nM for rat liver HDAC and IC50 = 100 nM for maize HDAC). Induces differentiation and inhibits proliferation (~2uM) of murine erythroleukemia cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 251456-60-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| M344 | M344 (D 237) is an inhibitor of histone deacetylase (IC50=100 nM) and an inducer of terminal cell fifferentiation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D 237; MS 344. CAS No. 251456-60-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13506. | |
| M 344 | M 344. Group: Biochemicals. Grades: Purified. CAS No. 251456-60-7. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| M351-0056 | M351-0056 is the agonist for the immune checkpoint protein VISTA, that reduces the secretion of VISTA-induced cytokines, promotes the T-cell proliferation induced by VISTA, and exhibits immunomodulatory activity. M351-0056 ameliorates Imiquimod (HY-B0180)-induced psoriatic dermatitis in mouse models[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1189495-81-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169853. | |
| M3541 | M3541 is a potent, ATP-competitive and selective ATM inhibitor with an IC50 of 0.25 nM. M3541 shows remarkable selectivity against other protein kinases. M3541 suppresses double-strand breaks (DSB) repair and has antitumor activities[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1360628-91-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-160096. | |
| m-3M3FBS | m-3M3FBS is a potent phospholipase C (PLC) activator. m-3M3FBS stimulates superoxide generation in human neutrophils, upregulates intracellular calcium concentration, and stimulates inositol phosphate generation in various cell lines. m-3M3FBS induces monocytic leukemia cell apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 200933-14-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19619. | |
| m-3M3FBS | m-3M3FBS. Group: Biochemicals. Grades: Purified. CAS No. 200933-14-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| M3-Nitrodienamine | Nitrodienamine is an inhibitor of Ca2+/Mg2+ ATPase. Grade: 95% (NMR). Molecular formula: C17H22N2O2. Mole weight: 286.37. | |
| M40 | M40. Group: Biochemicals. Grades: Purified. CAS No. 143896-17-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| M40 | M40 is a potent, non-selective antagonist of galanin receptor, and has no effect on chow or fat intake. Synonyms: M 40; M-40; H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2; L-Alaninamide, glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-; Glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-alaninamide; M 40 (peptide). Grade: ≥95%. CAS No. 143896-17-7. Molecular formula: C95H146N22O24. Mole weight: 1980.31. | |
| M40 acetate | M40 acetate is a potent, non-selective antagonist of galanin receptor, and has no effect on chow or fat intake. Synonyms: H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2.CH3CO2H; glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparagyl-L-seryl-L-alanyl-glycyl-L-tyrosyl-L-leucyl-L-leucyl-glycyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-alaninamide acetic acid; M 40 acetate. Grade: ≥95%. Molecular formula: C96H149N23O26. Mole weight: 2041.38. | |
| M435-1279 | M435-1279 is a UBE2T inhibitor. M435-1279 inhibits the Wnt/β-catenin signaling pathway hyperactivation through blocking UBE2T-mediated degradation of RACK1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1359431-16-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141891. | |
| M-4365 A1 | It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 A1 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics. Molecular formula: C31H53NO8. Mole weight: 567.75. | |
| M-4365 G1 | It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 G1 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics. And it also has a certain anti-Gram-negative bacteria activity. Molecular formula: C31H53NO7. Mole weight: 551.75. | |
| M-4365 G2 | It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 G2 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics. Synonyms: SCHEMBL192993. Molecular formula: C31H51NO8. Mole weight: 565.74. | |
| M443 | M443 is an irreversible and specific inhibitor of MRK, with an IC50<125 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1820684-31-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112274. | |
| M47 | M47 is a molecular glue that selectively destabilizes Cryptochrome 1 (CRY1) and increases degradation of the CRY1 in the nucleus. M47 enhances apoptosis in Ras-transformed P53-deficient mouse skin fibroblast lines and enhances life span in p53 knockout mice. M47 can be used in research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 890808-56-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148764. | |
| M4K-2009 | M4K-2009 is an orally bioactive ALK2 inhibitor with an IC50 of 13 nM. M4K-2009 exerts comparable inhibitory potency against wild-type and mutant ALK2G328V, ALK2R206H, and ALK2R258G. M4K-2009 exhibits moderate off-target inhibitory activity against hERG potassium channels. M4K-2009 can be used in studies related to diffuse intrinsic pontine glioma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2600795-07-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149591. | |
| M4K2163 dihydrochloride | M4K2163 dihydrochloride is a potent, selective, blood-brain barrier (BBB) permeable activin receptor-like kinase-2 (ALK2) inhibitor, with an IC50 of 19 nM. M4K2163 dihydrochloride can be used in the research of diffuse intrinsic pontine glioma (DIPG)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2863635-04-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155939. | |
| M4K2234 | M4K2234, a chemical probe, is an orally active, highly selective inhibitor of ALK1 and ALK2 with IC50 values of 7 nM and 14 nM, respectively. M4K2234 specifically blocks BMP signaling by inhibiting the phosphorylation of SMAD1/5/8. M4K2234 inhibits BMP7-stimulated reporter gene activity (IC50 = 16 nM). M4K2234 can be used for the investigation of ALK1/2-mediated biological processes and related diseases such as diffuse midline glioma (DMG) and fibrodysplasia ossificans progressiva (FOP)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2421141-51-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148234. | |
| M4-Nitrodienamine | Nitrodienamine is an inhibitor of Ca2+/Mg2+ ATPase. Grade: 95% (NMR). Molecular formula: C13H20N2O2. Mole weight: 236.31. | |
| M5N36 | M5N36 is a potent and selective Cdc25C inhibitor with IC50 values of 0.15, 0.19, 0.06 μM for Cdc25A, Cdc25B, Cdc25C, respectively. M5N36 shows anti-proliferative activity and increases the expression of p-CDK1 and p-CDK2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2832887-40-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132578. | |
| M5-Nitrodienamine | Nitrodienamine is an inhibitor of Ca2+/Mg2+ ATPase. Grade: 95% (NMR). Molecular formula: C17H24N2O2. Mole weight: 288.38. | |
| M617 | M617. Group: Biochemicals. Grades: Purified. CAS No. 860790-38-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| M617 | M617 is a selective galanin receptor 1 (GAL1) agonist, with Kis of 0.23 and 5.71 nM for GAL1 and GAL2, respectively. M617, acting through its central GAL1, can promote GLUT4 expression and enhance GLUT4 content in the cardiac muscle of type 2 diabetic rats[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 860790-38-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1131. | |
| M65 | M65 is a potent and specific antagonist of PAC1 receptor. Synonyms: PAC1 Receptor Antagonist M65; H-Cys-Asp-Ala-Thr-Cys-Gln-Phe-Arg-Lys-Ala-Ile-Asp-Asp-Cys-Gln-Lys-Gln-Ala-His-His-Ser-Asn-Val-Pro-Gly-Asn-Ser-Val-Phe-Lys-Glu-Cys-Met-Lys-Gln-Lys-Lys-Lys-Glu-Phe-Lys-Ala-NH2 (Disulfide bridge: Cys1-Cys5, Cys14-Cys32). Grade: ≥95%. CAS No. 1872440-65-7. Molecular formula: C205H326N64O61S5. Mole weight: 4823.57. | |
| M6766 | M6766 is a selective endoplasmic reticulum oxidoreductase 1α (ERO1α) inhibitor with an IC50 of 1.4 μM and a KD of 1.1 μM. M6766 also inhibits ERO1β with an IC50 of 7.2 μM. M6766 binds to the flavin adenine dinucleotide-binding pocket in ERO1α. M6766 inhibits granule secretion, αIIbβ3 integrin activation, Ca2+ mobilization, and platelet aggregation. M6766 can be used for the research of neurological disease, such as ischemic stroke[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 696628-90-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-175593. | |
| M68(Cetearyl Glucoside & Cetearyl Alcohol) | M68(Cetearyl Glucoside & Cetearyl Alcohol). CAS No. 246159-33-1. Product ID: CI-GU-0251. Alfa Chemistry - ISO 9001:32057 Certified. | |
| M700F048 | M700F048 is a major plant metabolite of fungicide Fluxapyroxad[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2056235-51-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-111741. | |
| M701 | M701 is a T-cell engager bispecific humanized antibody targeting epithelial cell adhesion molecule (EpCAM) and cluster of differentiation 3 (CD3). M701 binds to EpCAM on tumor cells and CD3 on T cells, thereby linking the two cell populations to achieve targeted cytotoxicity and T cell-mediated cytotoxicity. M701 is applicable to research related to advanced epithelial solid tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2933295-42-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991526. | |
| m7(3'OMeG)(5')pp-1-imidazol | m7(3'OMeG)(5')pp-1-imidazol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 2089461-53-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-172307. | |
| M7594_0037 | M7594_0037 is a potent inhibitor of human peptide deformylase (HsPDF) that has anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 774551-07-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-122097. | |
| m7G(N-biotin)pppG | m7G(N-biotin)pppG is an amino- and carboxy-functionalized dinucleotide 5' cap analog that is suitable for labeling with biotin or fluorescent tags by the employment of an in situ NHS activation strategy. Synonyms: P1-(2'-aminobiotinyl-2'-deoxy-N7-methylguanosin-5'-yl) P3-(guanosin-5'-yl) triphosphate. Molecular formula: C31H41N13O19P3S3 (free base). Mole weight: 1024.72 (free base). | |
| m7GP3G (Monomethylated Cap Analog) | m7GP3G (Monomethylated Cap Analog) is an indispensable compound extensively employed, supporting the synthesis of mRNAs possessing altered RNA cap structures. This remarkable compound assumes a pivotal function in advancing studies pertaining to gene expression and mRNA processing, particularly in the progressive frontiers of RNA vaccines and mRNA therapeutics. By enabling investigation into cap-dependent translation mechanisms, as well as facilitating the evaluation of mRNA stability and translational efficiency, this product fosters an unprecedented comprehension of intricate cellular processes. Synonyms: Guanosine 5'-(tetrahydrogen triphosphate), P''→5'-ester with 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purinium inner salt; m7Gp3G; m7GpppG; mG(5')ppp(5')G; P1-(5'-7-methyl-guanosyl) P3-(5'-(guanosyl))triphosphate; mCAP; m7G(5')ppp(5')G Cap Analog; N7-Methyl-Guanosine-5'-Triphosphate-5'-Guanosine; 7-Methyl-guanosine-5'-triphosphate-5'-guanosine; M7-GpppG. Grade: ≥95% by HPLC. CAS No. 62828-64-2. Molecular formula: C21H29N10O18P3. Mole weight: 802.43. | |
| m7GP3G (Monomethylated Cap Analog) sodium salt | m7GP3G (Monomethylated Cap Analog) sodium salt is a vital product in the biomedical industry used for studying mRNA capping and translation initiation. It serves as a crucial tool for investigating RNA transcription, translation processes and mRNA stability. By mimicking the natural RNA cap structure, m7GP3G sodium salt aids in understanding diseases like cancer and viral infections, ultimately enabling the development of effective researchs. Synonyms: m7G(5')ppp(5')G Sodium salt; P1-(5'-7-methyl-guanosyl) P3-(5'-(guanosyl))triphosphate, sodium salt; M7-GpppG sodium salt; Guanosine 5'-(tetrahydrogen triphosphate), P''→5'-ester with 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purinium inner salt, sodium salt; m7Gp3G sodium salt; m7GpppG sodium salt; mCAP sodium salt. Grade: ≥95% by HPLC. Molecular formula: C21H29N10O18P3 (free acid). Mole weight: 802.43 (free acid). | |
| m7GpppAmpG ammonium solution (100 mM) | m7GpppAmpG ammonium (m7G(5')ppp(5')(2'OMeA)pG ammonium) is a trinucleotide 5 end cap analog. m7GpppAmpG ammonium binds to eIF4E with a KD value of 45.6 nM. m7GpppAmpG ammonium caps RNA with a capping efficiency of 90%. m7GpppAmpG ammonium enhances mRNA stability and translation efficiency. m7GpppAmpG ammonium is used in mRNA therapeutic research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: m7G(5')ppp(5')(2'OMeA)pG ammonium. CAS No. 3080642-79-8. Pack Sizes: 20 μL; 50 μL; 100 μL; 200 μL. Product ID: HY-145974A. | |
| m7GTP-γ-aminophenyl-PEG4-Biotin | m7GTP-γ-aminophenyl-PEG4-Biotin is a groundbreaking theoretical compound used in unraveling the intricate intricacies of mRNA capping and RNA processing. Synonyms: 7-Methylguanosine-5'-[γ-(4-aminophenyl)-PEG4]-5'-triphosphate-Biotin. Grade: ≥ 95 % by HPLC. Molecular formula: C38H58N9O21P3S (free acid). Mole weight: 1101.27 (free acid). | |
| M-808 | M-808 is a highly potent and efficacious covalent Menin-MLL interaction inhibitor, with a binding IC50 value of 2.6 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2377335-74-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-133738. | |
| M871 | M871. Group: Biochemicals. Grades: Purified. CAS No. 908844-75-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| M871 | M871 is a selective galanin GAL2 receptor antagonist with Ki values of 420 and 13.1 nM for GAL1 and GAL2 receptors respectively. It blocks the pro-nociceptive effect of GAL2 receptor agonists. Synonyms: Galanin(2-13)Glu-His-(Pro)3(Ala-Leu)2Ala-amide. Grade: >98%. CAS No. 908844-75-7. Molecular formula: C108H163N27O28. Mole weight: 2287.64. | |
| M871 | M871 (Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide) is an orally active and selective galanin receptor type 2 (GalR2) antagonist. M871 exhibits Ki values of 13.1 nM, 420 nM and >10 μM for GalR2, GalR1 and GalR3 respectively. M871 relieves the mice allergic rhinitis by reducing IgE production, as well as the number of B cells in tissues. M871 can inhibit the nerve invasion of salivary adenoid cystic carcinoma (SACC) and alleviate myocardial ischemia-reperfusion injury. M871 can be used for research on GalR2-related diseases (such as epilepsy, pain)[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide. CAS No. 908844-75-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1130. | |
| M8891 | M8891 is an orally active, reversible and brain penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor with an IC50 of 54 nM and a Ki of 4.33 nM. M8891 does not inhibit MetAP-1 (IC50>10 μM)[1]. M8891 inhibits growth of primary endothelial cells as well as tumor cells and demonstrates antiangiogenic and antitumoral activity[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1464842-09-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133016. | |
| M8 B hydrochloride | M8 B hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 883976-12-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MA144 G2 | MA144 G2 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Synonyms: Antibiotic MA 144G2; 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-4-O-((2,3,6-trideoxy-alpha-L-glycero-hexopyranos-4-ulosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl(1-4)-O-3-(dimethylamino)-2,3,6-trideoxy-alpha-L-hexopyranosyl)oxy)-2,5,7,10-tetrahydroxy-, methyl ester. CAS No. 66808-28-4. Molecular formula: C42H53NO16. Mole weight: 827.87. | |
| MA144 M1 | MA144 M1 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Synonyms: Antibiotic MA 144M1; 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-4-((O-2,3,6-trideoxy-alpha-L-glycero-hexopyranosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1,4)-2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-2,5,7-trihydroxy-, methyl ester; aclacinomycin M; MA-144M1. CAS No. 64431-68-1. Molecular formula: C42H55NO15. Mole weight: 813.88. | |
| MA144 M2 | MA144 M2 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Synonyms: Antibiotic MA 144M2; 1-Hydroxy MA144 M1; 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-2,5,7,10-tetrahydroxy-4-((O-2,3,6-trideoxy-alpha-L-glycero-hexopyranosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1-4) 2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester; MA-144M2. CAS No. 64474-89-1. Molecular formula: C42H55NO16. Mole weight: 829.88. | |
| MA144 S1 | MA144 S1 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Synonyms: aclacinomycin S; Antibiotic MA 144S1; MA 144 S1; L-2-Deoxyfucosyl-L-rhodosaminyl-aklavinone. CAS No. 64431-69-2. Molecular formula: C36H45NO13. Mole weight: 699.74. | |
| MA144 U1 | MA144 U1 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Synonyms: Antibiotic MA 144U1; 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-4-O-((2,6-dideoxy-alpha-L-lyxo-hexopyranosyl(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl(1-4)-O-3-(dimethylamino)-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-2,7-dihydroxy-, methyl ester. CAS No. 65222-74-4. Molecular formula: C42H55NO16. Mole weight: 829.88. | |
| MA 2029 | MA 2029. Group: Biochemicals. Grades: Purified. CAS No. 287206-61-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MA-2029 | MA-2029 is a selective, orally active, and competitive motilin receptor antagonist (IC50=4.9 nM). MA-2029 is selective for the motilin receptor over various other receptors and ion channels. MA-2029 may be useful for gastrointestinal disorders associated with disturbed gastrointestinal motility[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 287206-61-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-107642. | |
| Maackiain | Maackiain. Group: Biochemicals. Alternative Names: (-)-Maackiain. Grades: Plant Grade. CAS No. 2035-15-6. Pack Sizes: 20mg. Molecular Formula: C16H12O5, Molecular Weight: 284.262999999999. US Biological Life Sciences. | Worldwide |
| Maackiain | Maackiain (DL-Maackiain) is an orally active multi-target inhibitor with anti-tumor activity and neuroprotective effects. Maackiain activates the AMPK, NLRP3 and Nrf2/HO-1 pathways, and inhibits key targets such as NF-κB, mTOR, MAO-B, NFATc1 and PKCδ, thereby precisely regulating processes including apoptosis, autophagy and pyroptosis. Maackiain also effectively inhibits microglial activation, osteoclast formation, and proliferation and invasion of tumor cells, and protects dopaminergic neurons from damage. Maackiain is applicable to the research of various diseases such as Alzheimer's disease, osteoporosis, sepsis and dengue fever[1][2][3][4][5][6][7][8][9]?. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DL-Maackiain. CAS No. 19908-48-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N0381. | |
| Mab Aspartate Decarboxylase-IN-1 | Mab Aspartate Decarboxylase-IN-1 is a potent aspartate decarboxylase (PanD) inhibitor with an IC50 value of 56.3 μM. Mab Aspartate Decarboxylase-IN-1 shows antibacterial activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2755712-12-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150637. | |
| Mab I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. A↑CCWGGT TGGWCC↓A. Activity: 1000-5000u.a./ml. Appearance: 10 X SE-buffer W, BSA. Storage: -20°C. Form: Liquid. Source: Microbacterium arborescens SE. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA, 50% glycerol. Cat No: ET-1129RE. |  |
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