A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
F-1 is a potent ALK and ROS1 dual inhibitor. It suppresses phospho-ALK and its relative downstream signaling pathways, with IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively. Grade: 98%. CAS No. 2244775-31-1. Molecular formula: C22H27ClN8O3S. Mole weight: 519.02.
F1063-0967
F1063-0967 is an inhibitor of dual-specificity phosphatase 26 (DUSP26) with IC50 of 11.62 μM. Synonyms: (Z)-2-hydroxy-4-(6-(5-(4-methylbenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)hexanamido)benzoic acid. CAS No. 613225-56-2. Molecular formula: C24H24N2O5S2. Mole weight: 484.59.
F-10748 C1
F-10748 C1 is originally isolated from Lophodermium sp. SANK 18496. It had inhibitory activity against fungal 1,3-β-glucan synthase with IC50 of 0.2-2 μg/mL. Synonyms: 2,4,12-Hexadecatrienoic acid, 7-hydroxy-8,14-dimethyl-, 3',4',5',6'-tetrahydro-3',5,7-trihydroxy-6'-(hydroxymethyl)-5'-[[6-O-(1-oxopentyl)hexopyranosyl]oxy]spiro[isobenzofuran-1(3H),2'-[2H]pyran]-4'-y l ester, (2E,4E,12E)-. Molecular formula: C42H62O16. Mole weight: 822.93.
F-10748 C2
F-10748 C2 is originally isolated from Lophodermium sp. SANK 18496. It had inhibitory activity against fungal 1,3-β-glucan synthase with IC50 of 0.2-2 μg/mL. Synonyms: 1,5-Anhydro-1-[2,4-dihydroxy-6-(hydroxymethyl)phenyl]-3-O-[(2E,4E,12E)-7-hydroxy-8,14-dimethyl-2,4,12-hexadecatrienoyl]-4-O-(6-O-pentanoylhexopyranosyl)hexitol. Molecular formula: C42H64O16. Mole weight: 824.95.
F-11334-A1
F-11334-A1 is a membrane binding inhibitor of N-SMase originally isolated from Acremonium murorum. Under neutral conditions, the IC50 (μg/mL) of it against rat brain microsomal N-SMase was 7.5. Synonyms: CHEMBL444672. CAS No. 171812-79-6. Molecular formula: C11H16O4. Mole weight: 212.24.
F-11334-A2
F-11334-A2 is a membrane binding inhibitor of N-SMase originally isolated from Acremonium murorum. Under neutral conditions, the IC50 (μg/mL) of it against rat brain microsomal N-SMase was >200. Synonyms: 2-(2-Hydroxy-2-propanyl)-2,3-dihydro-1-benzofuran-5-ol. CAS No. 465539-21-3. Molecular formula: C11H14O3. Mole weight: 194.23.
F-11334-A3
F-11334-A3 is a membrane binding inhibitor of N-SMase originally isolated from Acremonium murorum. Under neutral conditions, the IC50 (μg/mL) of it against rat brain microsomal N-SMase was >200. Synonyms: 2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-3,6-diol. CAS No. 465539-19-9. Molecular formula: C11H14O3. Mole weight: 194.23.
F-11334-B1
F-11334-B1 is a membrane binding inhibitor of N-SMase originally isolated from Acremonium murorum. Under neutral conditions, the IC50 (μg/mL) of it against rat brain microsomal N-SMase was 3.6. Synonyms: 2-[(1E)-3-hydroxy-3-methylbut-1-en-1-yl]benzene-1,4-diol. Molecular formula: C11H14O3. Mole weight: 194.23.
F-11334-B2
F-11334-B2 is a membrane binding inhibitor of N-SMase originally isolated from Acremonium murorum. Under neutral conditions, the IC50 (μg/mL) of it against rat brain microsomal N-SMase was 3.2. Synonyms: 2-[(1E)-3-methoxy-3-methylbut-1-en-1-yl]benzene-1,4-diol. Molecular formula: C12H16O3. Mole weight: 208.25.
F-12509A
It is produced by the strain of Trichopezizella barbata SANK 25395. F-12509A has competitive inhibitory activity against sphingosine kinase, and the Ki value is 18μmol/L. Synonyms: F12509A. CAS No. 191608-64-7. Molecular formula: C21H28O4. Mole weight: 344.44.
F13459
It is produced by the strain of Penicillum sp. F13459. F13459 had inhibitory activity against inosine 5'-phosphate dehydrogenase and it can inhibit the synthesis of Newcastle disease virus (NDV) hemagglutinin (HA) at 25 μg/mL. Molecular formula: C27H28O11. Mole weight: 528.50.
F1839-I
F1839-I is produced from Stachybotrys sp. Synonyms: F1839-I; 159096-49-8; (3R,4aS,7R,8R,8aS)-3,4'-dihydroxy-4,4,6',7,8a-pentamethylspiro[2,3,4a,5,6,7-hexahydro-1H-naphthalene-8,2'-3H-1-benzofuran]-7'-carbaldehyde; CHEMBL3092716; CHEBI:204378; HY-N11430; AKOS040761725; DA-73285; CS-0646802; (2R,2'R,4'aS,6'R,8'aS)-2',4-dihydroxy-1',1',4'a,6,6'-pentamethyl-spiro[3H-benzofuran-2,5'-decalin]-7-carbaldehyde; (3R,4aS,7R,8R,8aS)-3,4'-dihydroxy-4,4,6',7,8a-pentamethylspiro[2,3,4a,5,6,7-hexahydro-1H-naphthalene-8,2'-3H-1-benzouran]-7'-carbaldehyde. Grade: ≥98%. CAS No. 159096-49-8. Molecular formula: C23H32O4. Mole weight: 372.50.
F390B
It is an anti-tumor antibiotic produced by Penicillum sp.AJ 117292. Synonyms: F-390B; F-390-B; methyl (4R,4aS)-4-(acetyloxy)-8-hydroxy-6-methyl-9-oxo-4,9-dihydro-4aH-xanthene-4a-carboxylate. Molecular formula: C18H16O7. Mole weight: 344.31.
F390C
It is an anti-tumor antibiotic produced by Penicillum sp.AJ 117292. Synonyms: F-390C; F-390-C; methyl (4R,4aS)-4,8-dihydroxy-6-(hydroxymethyl)-9-oxo-4,9-dihydro-4aH-xanthene-4a-carboxylate. Molecular formula: C16H14O7. Mole weight: 318.28.
F420H2:quinone oxidoreductase
An enzyme complex that contains FAD and iron-sulfur clusters. The enzyme has been described in the archaea Methanosarcina mazei and Archaeoglobus fulgidus. Group: Enzymes. Synonyms: FqoF protein. Enzyme Commission Number: EC 1.1.98.4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0441; F420H2:quinone oxidoreductase; EC 1.1.98.4; FqoF protein. Cat No: EXWM-0441.
F44-A13
F44-A13 is an orally active and highly selective farnesoid X receptor (FXR) antagonist with an IC50 value of 1.1 μM. F44-A13 can optimize cholesterol metabolism and reduce its activity by inducing CYP7A1 expression. F44-A13 reduces levels of cholesterol, triglycerides, and low-density lipoprotein cholesterol (LDL-C) in mouse models. F44-A13 can be used in the study of metabolic diseases associated with lipid disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1338190-14-9. Pack Sizes: 1 mg. Product ID: HY-163436.
F5446 (Compound 1) is a selective small molecule inhibitor of SUV39H1 methyltransferase. F5446 decreases H3K9me3 deposition at the FAS promoter, increases Fas expression and increases colorectal carcinoma cell sensitivity to FasL-induced apoptosis in vitro. F5446 suppresses human colon tumor xenograft growth in vivo[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2304465-89-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-150190.
F7-Cholesterol
F7-Cholesterol. Alternative Names: 25,26,26,26,27,27,27-heptafluorocholesterol. CAS No. 153463-21-9. Purity: >99%. Product ID: ALCFA153463219. Molecular formula: C27H39OF7. Mole weight: 512.587. Alfa Chemistry - ISO 9001:32057 Certified.
F8BT
F8BT is a fluorene copolymer that is used as a light-emitting polymer (LEP) with low energy of lowest unoccupied molecular orbital (LUMO), high electron mobility and luminance. Alternative Names: Poly(9,9-dioctylfluorene-alt-benzothiadiazole),Poly[(9,9-di-n-octylfluorenyl-2,7-diyl)-alt-(benzo[2,1,3]thiadiazol-4,8-diyl)]. CAS No. 210347-52-7. Molecular formula: (C35H42N2S)n. Purity: 95%+.
F8T2
F8T2 is a fluorenated semiconducting polymer which can be used as a hole transporting layer with mobility of 0.02cm2 V-1s-1. It is highly stable in vacuum and UV based environment. Its liquid crystallinity allows it to form a self-ordered nanostructure on organic thin films. Alternative Names: Poly(9,9-dioctylfluorene-alt-bithiophene),Poly[(9,9-dioctylfluorenyl-2,7-diyl)-co-bithiophene]. CAS No. 210347-56-1. Molecular formula: (C37H44S2)n(C8H9)2.
FA2BG1 Glycan, 2-AA labelled
FA2BG1 Glycan, 2-AA labelled is a biomedical research compound used in glycomics studies. It's particularly useful in the analysis and detection of diseases such as cancer and autoimmune disorders where abnormal glycosylation patterns are often observed. Synonyms: FA2BG1 N-linked oligosaccharide; FA2G1 with bisecting GlcNAc; G1F with bisecting GlcNAc.
FA2BG1 Glycan, 2-AB labelled
FA2BG1 Glycan, 2-AB labelled, a crucial biomolecule with broad implications in the diagnosis and treatment of myriads of cancer types, beckons attention due to its capability as a diagnostic tool to detect alterations in cell surface glycosylation and track cancer treatment's efficacy. Synonyms: FA2BG1 N-linked oligosaccharide, 2-AB labelled; FA2G1 with bisecting GlcNAc, 2-AB labelled; G1F with bisecting GlcNAc, 2-AB labelled.
FA2B Glycan, 2-AA labelled
FA2B Glycan, 2-AA labelled is a prodigious compound, serving as an indispensable instrument for studying and comprehending intricate glycan structures. Renowned and heavily employed in the realm of glycobiology research, this remarkable product unfailingly facilitates an exhaustive exploration of glycosylation processes, as well as an in-depth analysis of the multifaceted interactions between glycans and proteins.
FA2B Glycan, 2-AB labelled
FA2B Glycan, 2-AB labelled.
FA2B N-Glycan
FA2B N-Glycan is a naturally occurring glycan presenting on N-linked glycoproteins. It exhibits pivotal significance in numerous cellular phenomena such as cell adhesion, signaling and immune response. It can be used to study glycosylation patterns and glycan functionality. Synonyms: Asialo, agalacto, core-fucosylated, bisected, bi-antennary N-linked glycan. Mole weight: 1667.
FA2G1 N-Glycan
FA2G1 N-Glycan is a compound assuming a paramount role in the comprehensive exploration and comprehension of glycoproteins alongside their intricate functionalities. With its widespread employment as a research tool, this N-glycan holds the potential for the profound investigation of diverse maladies encompassing cancer, inflammation and hereditary disorders. Synonyms: Asialo, core fucosylated, bi-antennary N-linked glycan; NA2G1F N-Glycan. CAS No. 721918-59-8. Molecular formula: C62H104N4O45. Mole weight: 1625.49.
FA 5859
FA 5859 is an amino acid compound produced by the strain of Emericella quidrilineata (IFO 5859), Aspergillus sp. 3704. It has the activity of inhibiting fatty acid degradation. Synonyms: 3-Acetamido-4-trimethylaminobutyric acid. CAS No. 98855-43-7. Molecular formula: C9H18N2O3. Mole weight: 202.25.
FAAH-IN-1
FAAH-IN-1 is a fatty acid amide hydrolase (FAAH) inhibitor, with IC50s of 145 nM and 650 nM for rat and human FAAH, respectively. Synonyms: FAAH-IN-1; CHEMBL2386560; SCHEMBL2681198; JCDQNWAFZWEYBZ-CVEARBPZSA-N; BDBM50434324; AKOS040733139; HY-111389; CS-0040311; (1S,2S)-2-(4-{5-[(5-Chloropyridin-2-yl)thio]-1H-imidazol-4-yl}phenyl)-N,N-dimethylcyclopropanecarboxamide; 1242441-47-9. CAS No. 1242441-47-9. Molecular formula: C20H19ClN4OS. Mole weight: 398.91.
FAAH inhibitor 1
Time-dependent preincubation study of FAAH inhibitor 1 was consistent with it being a reversible inhibitor. Activity-based protein-profiling (ABPP) evaluation of FAAH inhibitors 1 in rat tissues revealed that it had exceptional selectivity and no off-target activity with respect to other serine hydrolases. Molecular shape overlay of FAAH inhibitor 1 with a known FAAH inhibitor indicated that these compounds might act as transitionstate analogues, forming putative hydrogen bonds with catalytic residues and mimicking the charge distribution of the tetrahedral transition state. FAAH inhibitors 1 was exclusively specific against FAAH in rat brain and had no missing protein bands in all the other tissues that were tested. Synonyms: FAAH inhibitor 1. Grade: >98%. CAS No. 326866-17-5. Molecular formula: C24H23N3O3S3. Mole weight: 497.65.
FA-Ala-Arg-OH
FA-Ala-Arg-OH is a substrate for human plasma carboxypeptidase N and membrane-bound carboxypeptidase D. Synonyms: Furylacryloylalanylarginine; Furylacryloyl-alanyl-arginine; L-Arginine, N(2)-(N-(3-(2-furanyl)-1-oxo-2-propenyl)-L-alanyl)-. CAS No. 76079-06-6. Molecular formula: C16H23N5O5. Mole weight: 365.38.
Fa-AMP1
Fa-AMP1 is produced by Fagopyrum esculentum. The concentration of peptide required for 50% inhibition (IC50) of the growth of plant pathogenic fungi, and Gram-positive and -negative bacteria is 11 to 36 microg/ml. Mole weight: 3879.
Fa-AMP2
Fa-AMP2 is produced by Fagopyrum esculentum. The concentration of peptide required for 50% inhibition (IC50) of the growth of plant pathogenic fungi, and Gram-positive and -negative bacteria is 11 to 36 microg/ml. Mole weight: 3906.
Fabatin-1
Fabatin-1 is active against both Gram-negative and Gram-positive bacteria, but is inactive against the yeasts Saccharomyces cerevisiae and Candida albicans.
Fabatin-2
Fabatin-2 is active against both Gram-negative and Gram-positive bacteria, but is inactive against the yeasts Saccharomyces cerevisiae and Candida albicans.
Fabesetron
Fabesetron is an orally active 5-HT3 receptor antagonist with 5-HT4 receptor antagonistic activity. Fabesetron can be used in the study for both acute and delayed emesis induced by cancer chemotherapy. Synonyms: (+)-(R)-8,9-Dihydro-10-methyl-7-((5-methylimidazol-4-yl)methyl)pyrido(1,2-a)indol-6(7H)-one; Pyrido[1,2-a]indol-6(7H)-one, 8,9-dihydro-10-methyl-7-[(4-methyl-1H-imidazol-5-yl)methyl]-, (7R)-; FK1052; FK-1052. CAS No. 129300-27-2. Molecular formula: C18H19N3O. Mole weight: 293.36.
Fabiatrin
Fabiatrin. Group: Biochemicals. Grades: Plant Grade. CAS No. 18309-73-4. Pack Sizes: 10mg. Molecular Formula: C21H26O13, Molecular Weight: 486.43. US Biological Life Sciences.
Worldwide
FABP1-IN-1
FABP1-IN-1 (44) is a selective FABP1 inhibitor, with an IC50 of 4.46 μM. FABP1-IN-1 (44) can be used for the research of NASH[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3048021-44-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158127.
Fabp4/5-IN-2
Fabp4/5-IN-2 is a Fabp4/5 inhibitor. Grade: >98%. CAS No. 1227413-92-4. Molecular formula: C19H15ClN4O2. Mole weight: 366.81.
FABP-IN-2
FABP-IN-2 is a novel FABP3 ligand. FABP-IN-2 inhibits FABP3/FABP4 with an IC50 of 1.16 μM and 4.27 μM respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1426533-99-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148665.
FABPs ligand 6
FABPs ligand 6 (MF6) is an FABP5 and FABP7 inhibitor with KD values of 874 nM and 20 nM, respectively. FABPs ligand 6 can be used for multiple sclerosis research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MF6. CAS No. 2988135-14-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145990.
Facinicline
Facinicline is a partial agonist of the nicotinic alpha-7 (α7) receptor. It is used for the oral treatment of Alzheimer's. It was being co-developed by Roche and was in clinic phase 2 trials with no progress. Uses: Facinicline is used for the oral treatment of alzheimer's. Synonyms: Facinicline; RG-3487; MEM-3454; R-3487; RO-5313534; RG3487; MEM3454; R-487; RO5313534; RG 3487; MEM 3454; R 3487; RO 5313534; (S)-N-(quinuclidin-3-yl)-1H-indazole-3-carboxamide; N-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-1H-indazole-3-carboxamide. Grade: 98%. CAS No. 677306-35-3. Molecular formula: C15H18N4O. Mole weight: 270.34.
FACL4 Antibody [B15L22]
ACSL4,FACL4. Group: Antibodies. Alternative Names: ACSL4,FACL4. Pack Sizes: 20ul. Product ID: F1153. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years.
United States; Europe
F-actin monooxygenase
The enzyme, characterized from the fruit fly Drosophila melanogaster, is a multi-domain oxidoreductase that acts as an F-actin disassembly factor. The enzyme selectively reduces two L-Met residues of F-actin, causing fragmentation of the filaments and preventing repolymerization. Free methionine is not a substrate. The reaction is stereospecific and generates the (R)-sulfoxide. Group: Enzymes. Synonyms: MICAL (gene name). Enzyme Commission Number: EC 1.14.13.225. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0828; F-actin monooxygenase; EC 1.14.13.225; MICAL (gene name). Cat No: EXWM-0828.
Factor B-IN-1
Factor B-IN-1 is an inhibitor of Factor B. (Extracted from patent WO2013164802A1, Example 24). Synonyms: 1H-Benzimidazole-6-carbonitrile, 2-[hydroxy(5-methoxy-7-methyl-1H-indol-4-yl)methyl]-; 2-[Hydroxy-(5-methoxy-7-methyl-1H-indol-4-yl)methyl]-1H-benzimidazole-6-carbonitrile; 2-[hydroxy(5-methoxy-7-methyl-1H-indol-4-yl)methyl]-1H-1,3-benzodiazole-6-carbonitrile. Grade: ≥95%. CAS No. 1481631-75-7. Molecular formula: C19H16N4O2. Mole weight: 332.36.
Factor D inhibitor 6
Factor D inhibitor 6 is a potent, highly selective and orally active inhibitor of factor D (FD) with an IC50 of 30 nM and a Kd of 6 nM. Factor D inhibitor 6 is inactive against factor B, lassical and lectin complement-pathway activation, and a broad assay panel of receptors, ion channels, kinases and proteases. Synonyms: 1-{2-[(1R,3S,5R)-3-{[(1R)-1-(3-Chloro-2-fluorophenyl)ethyl]carbamoyl}-2-azabicyclo[3.1.0]hex-2-yl]-2-oxoethyl}-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; 2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[2-[3-(aminocarbonyl)-1H-pyrazolo[3,4-c]pyridin-1-yl]acetyl]-N-[(1R)-1-(3-chloro-2-fluorophenyl)ethyl]-, (1R,3S,5R)-. Grade: ≥95%. CAS No. 1386455-51-1. Molecular formula: C23H22ClFN6O3. Mole weight: 484.91.
Factor D inhibitor 6
Factor D inhibitor 6 is a potent, highly selective and orally active factor D (FD) inhibitor with an IC50 of 30 nM and a Kd of 6 nM. Factor D inhibitor 6 is inactive against factor B, lassical and lectin complement-pathway activation, and a broad assay panel of receptors, ion channels, kinases and proteases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1386455-51-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122700.
factor-independent urate hydroxylase
This enzyme was previously thought to be a copper protein, but it is now known that the enzymes from soy bean (Glycine max), the mould Aspergillus flavus and Bacillus subtilis contains no copper nor any other transition-metal ion. The 5-hydroxyisourate formed decomposes spontaneously to form allantoin and CO2, although there is an enzyme-catalysed pathway in which EC 3.5.2.17, hydroxyisourate hydrolase, catalyses the first step. The enzyme is different from EC 1.14.13.113 (FAD-dependent urate hydroxylase). Group: Enzymes. Synonyms: uric acid oxidase; uricase; uricase II; urate oxidase. Enzyme Commission Number: EC 1.7.3.3. CAS No. 9002-12-4. UO. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1626; factor-independent urate hydroxylase; EC 1.7.3.3; 9002-12-4; uric acid oxidase; uricase; uricase II; urate oxidase. Cat No: EXWM-1626.
Factrel
Factrel, also known as gonadorelin hydrochloride, is a synthetic decapeptide gonadotropin-releasing hormone (GnRH) identical in structure to the naturally occurring hypothalamic peptide. It is formulated as the hydrochloride salt and consists of the sequence pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2. Applications: Indicated for the evaluation of hypothalamic-pituitary-gonadal function and in reproductive endocrinology diagnostics. factrel is a synthetic gnrh identical to native hypothalamic hormone, used to assess pituitary reserve capacity and diagnose gonadotropin deficiency in infertility workups. Category: Active pharmaceutical ingredients. Synonyms: Gonadorelin HCl. CAS No. 51952-41-1. Product ID: API51952411. Molecular formula: C55H76ClN17O13. Mole weight: 1218.7. InChIKey: UPRWQSQENCASAD-HBBGHHHDSA-N. Appearance: Solid.
Factumycin
It is a polyene antibiotic produced by the strain of Streptomyces lavendulae MA-4758. It has the activity of anti-gram-positive bacteria and gram-negative bacteria, and is an animal growth promoter. Synonyms: Antibiotic A 40A; Mocimycin, 14,17-deepoxy-14,15-didehydro-15,30-dideoxy-17-hydroxy-1-methyl-, (14Z)-; 2H-Pyran-2-acetamide, N-[(2E,4E,6S,7S,9S,10E,12E,14E,16E)-18-(1,2-dihydro-4-hydroxy-1-methyl-2-oxo-3-pyridinyl)-8,9-dihydroxy-6-methoxy-5,7,17-trimethyl-18-oxo-2,4,10,12,14,16-octadecahexaen-1-yl]-a-ethyltetrahydro-2,4-dihydroxy-5,5-dimethyl-6-(1E,3Z)-1,3-pentadien-1-yl-, (aS,2S,4S,6S)-. CAS No. 84600-89-5. Molecular formula: C44H62N2O10. Mole weight: 778.97.
FAD-AMP lyase (cyclizing)
Requires Mn2+ or Co2+. While FAD was the best substrate tested, the enzyme also splits ribonucleoside diphosphate-X compounds in which X is an acyclic or cyclic monosaccharide or derivative bearing an X-OH group that is able to attack internally the proximal phosphorus with the geometry necessary to form a P=X product; either a five-atom monocyclic phosphodiester or a cis-bicyclic phosphodiester-pyranose fusion. The reaction is strongly inhibited by ADP or ATP but is unaffected by the presence of the product, cFMN. Group: Enzymes. Synonyms: FMN cyclase; FAD AMP-lyase (cyclic-FMN-forming). Enzyme Commission Number: EC 4.6.1.15. CAS No. 208349-48-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5352; FAD-AMP lyase (cyclizing); EC 4.6.1.15; 208349-48-8; FMN cyclase; FAD AMP-lyase (cyclic-FMN-forming). Cat No: EXWM-5352.
FadD32 Inhibitor-1
FadD32 inhibitor-1 has anti-tuberculosis activity and is an effective FadD32 inhibitor. CAS No. 2081969-24-4. Molecular formula: C24H20ClN3O. Mole weight: 401.89.
FAD-dependent glucose dehydrogenase
FAD-dependent glucose dehydrogenase (EC 1.1.5.9), or glucose dehydrogenase (FAD)/Pseudomonas glucose dehydrogenase. FAD-dependent glucose dehydrogenase is insensitive to O2 and displays high substrate specificity to glucose and thus is especially attractive enzymes for use in glucose biosensor applications[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FAD-GDH; Glucose 1-dehydrogenase. CAS No. 37250-84-3. Pack Sizes: 1 KU. Product ID: HY-E70014.
FAD-dependent urate hydroxylase
A flavoprotein. The reaction is part of the purine catabolic pathway in the bacterium Klebsiella pneumoniae. The enzyme is different from EC 1.7.3.3, factor-independent urate hydroxylase, found in most plants, which produces hydrogen peroxide. The product of the enzyme is a substrate for EC 3.5.2.17, hydroxyisourate hydrolase. Group: Enzymes. Synonyms: HpxO enzyme; FAD-dependent urate oxidase; urate hydroxylase. Enzyme Commission Number: EC 1.14.13.113. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0713; FAD-dependent urate hydroxylase; EC 1.14.13.113; HpxO enzyme; FAD-dependent urate oxidase; urate hydroxylase. Cat No: EXWM-0713.
FAD diphosphatase
The plant enzyme also hydrolyses NAD+ and NADH; the animal enzyme hydrolyses NAD+ and CoA at about half of the rate of hydrolysis of FAD. May be identical with EC 3.6.1.9 nucleotide diphosphatase. Group: Enzymes. Synonyms: FAD pyrophosphatase; riboflavin adenine dinucleotide pyrophosphatase; flavin adenine dinucleotide pyrophosphatase; riboflavine adenine dinucleotide pyrophosphatase; flavine adenine dinucleotide pyrophosphatase. Enzyme Commission Number: EC 3.6.1.18. CAS No. 37289-30-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4602; FAD diphosphatase; EC 3.6.1.18; 37289-30-8; FAD pyrophosphatase; riboflavin adenine dinucleotide pyrophosphatase; flavin adenine dinucleotide pyrophosphatase; riboflavine adenine dinucleotide pyrophosphatase; flavine adenine dinucleotide pyrophosphatase. Cat No: EXWM-4602.
FAD disodium salt
FAD disodium salt is the salt form of FAD, which is a coenzyme that facilitates the transfer of electrons by flavoenzymes in oxidation-reduction reactions in cells. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Riboflavin 5'-(trihydrogen diphosphate), P'→5'-ester with adenosine, sodium salt (1:2); Riboflavin 5'-(trihydrogen diphosphate), P'→5'-ester with adenosine, disodium salt; FAD sodium salt; Flavin adenine dinucleotide sodium salt. CAS No. 84366-81-4. Molecular formula: C27H31N9Na2O15P2. Mole weight: 829.52.
Fadogia Agrestis Stem Powder(Alkemist Approved)
Fadogia Agrestis Stem Powder(Alkemist Approved).
CA, FL & NJ
Fadolmidine HCl
Fadolmidine Hydrochloride, is a novel α2-adrenoceptor (α2-AR) agonist, having antinociception properties. It can be used for the control of inflammatory, postoperative and neuropathic pain. Synonyms: Fadolmidine HCl; MPV-2426; MPV 2426; MPV2426; 3-((1H-imidazol-4-yl)methyl)-2,3-dihydro-1H-inden-5-ol hydrochloride. Grade: 97%. CAS No. 189353-32-0. Molecular formula: C13H15ClN2O. Mole weight: 250.72.
FAD:protein FMN transferase
The enzyme catalyses the transfer of the FMN portion of FAD and its covalent binding to the hydroxyl group of an L-threonine residue in a target flavin-binding protein such as the B and C subunits of EC 1.6.5.8, NADH:ubiquinone reductase (Na+-transporting). Requires Mg2+. Group: Enzymes. Synonyms: flavin transferase; apbE (gene name). Enzyme Commission Number: EC 2.7.1.180. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3012; FAD:protein FMN transferase; EC 2.7.1.180; flavin transferase; apbE (gene name). Cat No: EXWM-3012.
Fadraciclib
Fadraciclib (CYC065) is a second-generation, orally available ATP-competitive inhibitor of CDK2/CDK9 kinases[1] with IC50s of 5 and 26 nM, respectively[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CYC065. CAS No. 1070790-89-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101212.
FAD reductase (NADH)
The enzyme from Burkholderia phenoliruptrix can reduce either FAD or flavin mononucleotide (FMN) but prefers FAD. Unlike EC 1.5.1.36, flavin reductase (NADH), the enzyme can not reduce riboflavin. The enzyme does not use NADPH as acceptor. Group: Enzymes. Synonyms: NADH-FAD reductase; NADH-dependent FAD reductase; NADH:FAD oxidoreductase; NADH:flavin adenine dinucleotide oxidoreductase. Enzyme Commission Number: EC 1.5.1.37. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1518; FAD reductase (NADH); EC 1.5.1.37; NADH-FAD reductase; NADH-dependent FAD reductase; NADH:FAD oxidoreductase; NADH:flavin adenine dinucleotide oxidoreductase. Cat No: EXWM-1518.
FAD reductase [NAD(P)H]
This enzyme, isolated from the bacterium Geobacillus thermodenitrificans, participates in the pathway of tryptophan degradation. The enzyme is part of a system that also includes a bifunctional riboflavin kinase/FMN adenylyltransferase and EC 1.14.14.8, anthranilate 3-monooxygenase (FAD). It can reduce either FAD or flavin mononucleotide (FMN) but prefers FAD. The enzyme has a slight preference for NADPH as acceptor. cf. EC 1.5.1.37, FAD reductase (NADH). Group: Enzymes. Synonyms: GTNG_3158 (gene name). Enzyme Commission Number: EC 1.5.1.45. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1526; FAD reductase [NAD(P)H]; EC 1.5.1.45; GTNG_3158 (gene name). Cat No: EXWM-1526.
Fadrozole
Fadrozole is a potent and selective inhibitor of aromatase with IC50 of 4.5 nM. Uses: Antineoplastic agents, hormonal. Synonyms: Benzonitrile, 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)-; CGS 16949A (free base); 5-p-cyanophenyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine; 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonitrile. Grade: 95%. CAS No. 102676-47-1. Molecular formula: C14H13N3. Mole weight: 223.27.
Fadrozole hydrochloride
Fadrozole hydrochloride (CGS 16949A) is a potent, selective and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CGS 16949A; (Rac)-FAD286 hydrochloride. CAS No. 102676-31-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14247.
Fadrozole Hydrochloride
Fadrozole (INN, marketed as Afema by Novartis) is an aromatase inhibitor that has been introduced in Japan for the treatment of breast cancer. Synonyms: Benzonitrile, 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)-, hydrochloride (1:1); Benzonitrile, 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)-, monohydrochloride; Afema; CGS 16949; CGS 16949A. Grade: 99%. CAS No. 102676-31-3. Molecular formula: C14H14ClN3. Mole weight: 259.73.
FAD synthetase
Requires Mg2+ and is highly specific for ATP as phosphate donor. The cofactors FMN and FAD participate in numerous processes in all organisms, including mitochondrial electron transport, photosynthesis, fatty-acid oxidation, and metabolism of vitamin B6, vitamin B12 and folates. While monofunctional FAD synthetase is found in eukaryotes and in some prokaryotes, most prokaryotes have a bifunctional enzyme that exhibits both this activity and that of EC 2.7.1.26, riboflavin kinase. Group: Enzymes. Synonyms: FAD pyrophosphorylase; riboflavin mononucleotide adenylyltransferase; adenosine triphosphate-riboflavin mononucleotide transadenylase; adenosine triphosphate-riboflavine mononucleotide transadenylase; riboflavin adenine dinucleotide pyrophosp. Enzyme Commission Number: EC 2.7.7.2. CAS No. 9026-37-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3234; FAD synthetase; EC 2.7.7.2; 9026-37-3; FAD pyrophosphorylase; riboflavin mononucleotide adenylyltransferase; adenosine triphosphate-riboflavin mononucleotide transadenylase; adenosine triphosphate-riboflavine mononucleotide transadenylase; riboflavin adenine dinucleotide pyrophosphorylase; riboflavine adenine dinucleotide adenylyltransferase; flavin adenine dinucleotide synthetase; FADS; FMN adenylyltransferase. Cat No: EXWM-3234.
FaeI
One unit of the enzyme is the amount required to hydrolyze 1 μg of pUC19 DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 3-fold overdigestion with enzyme more then 90% of the dna fragments can be ligated with t4 dna ligase at 16°c and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. CATG↑ ↓GTAC. Activity: 500-2000 u.a./ml. Appearance: 10 X SE-buffer FaeI, BSA. Storage: -20°C. Form: Liquid. Source: Flavobacterium aquatile N3. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1105RE.
FA-Glu-Glu-OH
FA-Glu-Glu-OH is the preferred substrate for carboxypeptidase O in humans and zebrafish. Synonyms: N-[(2E)-3-(2-Furyl)-2-propenoyl]-L-α-glutamyl-L-glutamic acid; L-Glutamic acid, N-[(2E)-3-(2-furanyl)-1-oxo-2-propen-1-yl]-L-α-glutamyl-; (S)-2-((S)-4-carboxy-2-((E)-3-(furan-2-yl)acrylamido)butanamido)pentanedioic acid; FA-EE-OH. Grade: ≥90%. CAS No. 1374423-90-1. Molecular formula: C17H20N2O9. Mole weight: 396.35.
FA-Gly-Abu-NH2
FA-Gly-Abu-NH2 can be used as substrate in a substrate specificity study of thermolysin. Synonyms: 3-(2-Furyl)acryloyl-Gly-Abu-NH2. Grade: ≥ 98%. CAS No. 67607-48-1. Molecular formula: C13H17N3O4. Mole weight: 279.30.
FA-Gly-Abu-NH2
FA-Gly-Abu-NH2. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 50mg, 100mg. US Biological Life Sciences.