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| Product | Description | |
|---|---|---|
| T0070907 | T0070907 is a potent inhibitor of PPARγ (peroxisome proliferator activator receptor γ ) that induces G2/M arrest and enhances the effect of radiation in human cervical cancer cells through mitotic catastrophe. It also acts as an antagonist of PPARγ that suppresses breast cancer cell proliferation and motility via both PPARgamma-dependent and -independent mechanisms. Group: Inhibitors. CAS No. 313516-66-4. Pack Sizes: 5mg. Product ID: S2871. Formula: C12H8ClN3O3. Smiles: C1=CC(=C(C=C1[N+](=O)[O-])C(=O)NC2=CC=NC=C2)Cl. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| T0070907 | T0070907 is a potent PPARγ antagonist with a Ki of 1 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 313516-66-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13202. |  |
| T 0070907 | T 0070907. Group: Biochemicals. Grades: Purified. CAS No. 313516-66-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| T0070907 (2-Chloro-5-nitro-N-4-pyridinyl-benzamide) | T0070907 is a potent and selective antagonist of the human PPARy (IC50=1nm). T0070907 suppresses breast cancer cell proliferation and motility via both PPARy-dependent and -independent mechanisms. Group: Biochemicals. Grades: Highly Purified. CAS No. 313516-66-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| T0080 | T0080 is a central nervous system-penetrant FPR1 inhibitor. By functionally blocking the FPR1 signaling pathway, T0080 effectively reduces neutrophil infiltration into ischemic brain tissue and maintains the integrity of the blood-brain barrier. T0080 alleviates tPA-associated hemorrhagic transformation, inhibits demyelination responses and the expression of NOX2. T0080 also possesses anti-apoptotic (apoptosis) and anti-inflammatory properties, thereby protecting myelin and reducing neurological deficits. T0080 is widely used in studies related to ischemic stroke complicated by hemorrhagic transformation after tPA thrombolysis, as well as multiple sclerosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2785323-68-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-173591. | |
| T01-1 | T01-1 is an anticancer agent (camptothecin derivative) with good anti-proliferative activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KL610023. CAS No. 2356229-14-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148185. | |
| T025 | T025 is an orally active and highly potent inhibitor of Cdc2-like kinase (CLKs), with Kd values of 4.8, 0.096, 6.5, 0.61, 0.074, 1.5 and 32 nM for CLK1, CLK2, CLK3, CLK4, DYRK1A, DYRK1B and DYRK2, respectively. T025 induces caspase-3/7-mediated cell apoptosis. T025 reduces CLK-dependent phosphorylation. T025 exerts anti-proliferative activities in both hematological and solid cancer cell lines (IC50 values: 30-300 nM). T025 has an anti-tumor efficiency, mainly for MYC-driven disease research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2407433-00-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112296. | |
| T-0632 | T-0632 is a CCK A receptor antagonist that exhibits significant pharmacological properties in in vitro studies. T-0632 competitively inhibits the binding of [125I]CCK-8 to rat pancreatic CCK A receptors with a K_i value of 0.24 nM, which is significantly lower than the K_i value for guinea pig CCK B receptors. T-0632 has higher selectivity in inhibiting CCK-8-stimulated pancreatic enzyme release, with an IC_50 value of 5.0 nM, which is more advantageous than L-364,718 and loxiglumide. In rabbit gallbladder smooth muscle, the antagonistic effects of T-0632 and loxiglumide are reversible, while L-364,718 shows a persistent inhibitory effect. These results indicate that T-0632 is a highly potent, reversible and more selective CCK A receptor antagonist. Uses: Scientific research. Category: Signaling pathways. CAS No. 169042-78-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-19261. | |
| T07C4.4 | T07C4.4 is an antibacterial peptide isolated from Leptodactylus syphax. Synonyms: Met-Thr-Arg-Ile-Leu-Pro-Cys-Leu-Phe-Leu-Val-Leu-Leu-Ala-Ala-Ala-Pro-Leu-Leu-Ala-Asn-Pro-Ala-Asn-Pro-Leu-Asn-Leu-Lys-Lys-His-His-Gly-Val-Phe. Grade: >97%. |  |
| T0901317 | T0901317 is an orally active and highly selective LXR agonist with an EC50 of 20 nM for LXRα[1]. T0901317 activates FXR with an EC50 of 5 μM[2]. T0901317 is RORα and RORγ dual inverse agonist with Ki values of 132 nM and 51 nM, respectively[3]. T0901317 induces apoptosis and inhibits the development of atherosclerosis in low-density lipoprotein (LDL) receptor-deficient mice[4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 293754-55-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-10626. | |
| T 0901317 | T 0901317. Group: Biochemicals. Grades: Purified. CAS No. 293754-55-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| T 0901317 (T-0901317, T0901317) | T 0901317 (T-0901317, T0901317). Group: Biochemicals. Alternative Names: N-[4- (1, 1, 1, 3, 3, 3-hexafluoro-2-hydroxypropan-2-yl) phenyl]-N- (2, 2, 2-trifluoroethyl) benzenesulfonamide. Grades: Highly Purified. CAS No. 293754-55-9. Pack Sizes: 50mg. Molecular Formula: C17H12F9NO3 , Molecular Weight: 481.3. US Biological Life Sciences. | Worldwide |
| T-10418 | T-10418 is a potent and highly selective G2A/GPR132 agonist. T-10418 has an EC50 of 0.82 μM for human G2A activation. T-10418 has good water solubility, metabolic stability, and pharmacokinetic properties. T-10418 can be used for the research of various diseases such as neuropathic pain, acute myeloid leukemia, and inflammation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1608784-68-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163763. | |
| T-1101 tosylate | T-1101 tosylate (TAI-95 tosylate) is the tosylate salt form of T-1101 (HY-120356). T-1101 tosylate is an orally active inhibitor for mitose regulating highly expressed oncoprotein 1 (Hec1). T-1101 tosylate blocks the interaction between Hec1 and NEK2, exhibits cytotoxicity in human liver cancer cells with GI50 of 15-70 nM. T-1101 tosylate induces apoptosis in Huh-7. T-1101 tosylate exhibits antitumor efficacy in mouse models[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAI-95 tosylate. CAS No. 2250404-95-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120356A. | |
| T16Ainh - A01 | T16Ainh - A01. Group: Biochemicals. Grades: Purified. CAS No. 552309-42-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| T16Ainh-A01 | T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 μM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 552309-42-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100612. | |
| T-2307 | T-2307, an arylamidine, has antifungal activities in vitro and in vivo. T-2307 exhibits broad-spectrum activity against clinically significant pathogens, including Candida species (MIC range, 0.00025 to 0.0078 μg/ml), Cryptococcus neoformans (MIC range, 0.0039 to 0.0625 μg/ml), and Aspergillus species (MIC range, 0.0156 to 4 μg/mL) [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 873546-31-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114220. | |
| T 2588G | T 2588G. Group: Biochemicals. Alternative Names: (Z)-2-Amino-a-(methoxyimino)-N-(2-oxoethyl)-4-thiazoleacetamide; THR 221V. Grades: Highly Purified. CAS No. 104301-63-5. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C8H10N4O3S. US Biological Life Sciences. | Worldwide |
| T2AA | T2AA is a monoubiquitinated proliferating cell nuclear antigen (PCNA) inhibitor that prevents DNA repair, increases double-strand break (DSB) formation and promotes necroptosis and cell cycle arrest in G1 phase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1380782-27-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110111. | |
| T2-induced deoxynucleotide kinase | dTMP and dAMP can act as acceptors; dATP can act as donor. Group: Enzymes. Enzyme Commission Number: EC 2.7.4.12. CAS No. 37278-99-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3193; T2-induced deoxynucleotide kinase; EC 2.7.4.12; 37278-99-2. Cat No: EXWM-3193. |  |
| t2t | t2t. CAS No. 1201800-83-0. Molecular formula: C39H27N3. Mole weight: 537.6g/mol. IUPAC Name: 2,4,6-tris(3-phenylphenyl)-1,3,5-triazine. SMILES: C1=CC=C(C=C1)C2=CC(=CC=C2)C3=NC(=NC(=N3)C4=CC=CC(=C4)C5=CC=CC=C5)C6=CC=CC(=C6)C7=CC=CC=C7. InChI: InChI=1S/C39H27N3/c1-4-13-28(14-5-1)31-19-10-22-34(25-31)37-40-38(35-23-11-20-32(26-35)29-15-6-2-7-16-29)42-39(41-37)36-24-12-21-33(27-36)30-17-8-3-9-18-30/h1-27H. |  |
| T-2 Tetraol | It is a kind of nature type-A trichothecene mycotoxin, could be used as a reference standard in quantitative analysis of food stuffs. Synonyms: Trichothec-9-ene-3α,4β,8α,15-tetrol, 12,13-epoxy-; (3α,4β,8α)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol; T 2 toxin tetraol; Toxin T 2 tetraol; Toxin T 4. Grade: ≥95%. CAS No. 34114-99-3. Molecular formula: C15H22O6. Mole weight: 298.33. | |
| T-2 Toxin | T-2 toxin is a common trichothecene mycotoxin produced by Fusarium species, which can infect grain crops causing alimentary toxic aleukia in humans and animals. It triggers a ribotoxic response through its high binding affinity to peptidyl transferase, which is an integral part of the 60S ribosomal subunit, resulting in activation of JNK/p38 MAPKs, interferes with the metabolism of membrane phospholipids, and increases liver lipid peroxides.1 T-2 toxin is highly cytotoxic to macrophages, inducing apoptosis in primary porcine alveolar macrophage cells with an IC50 value of 19.47 nM. At 3 nM it decreases the production of inflammatory mediators (IL-1 β, TNFα, and nitric oxide), TLR4, and TLR2/6 agonists.2. Group: Biochemicals. Alternative Names: (3α,4 β,8α)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 4,15-Diacetate 8-(3-Methylbutanoate); 12,13-Epoxytrichothec-9-ene-3α,4 β,8α,15-tetrol 4,15-Diacetate 8-Isovalerate; 4 β,15-Diacetoxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-en-3α-ol; 8α-(3-Methylbutyryloxy)-4 β,15-diacetoxyscirp-9-en-3α-ol; Fusariotoxin T 2; Insariotoxin; Mycotoxin T 2; NSC 138780; T 2; T 2 mycotoxin; T-2 Lienomycin; Toxin T 2. Grades: Highly Purified. CAS No. 21259-20-1. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| T2 toxin triol | T2 toxin triol. Group: Biochemicals. Alternative Names: Toxin T 3; (3a,4b,8a)-12,13-Epoxy-trichothec-9-ene-3,4,8,15-tetrol 8-(3-methylbutanoate); Deacetyl HT 2 toxin. Grades: Highly Purified. CAS No. 34114-98-2,97373-21-2. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C20H30O7. US Biological Life Sciences. | Worldwide |
| T-2 Toxin Triol | T-2 Toxin Triol is a type-A trichothecene mycotoxin produced by Fusarium, itself a metabolite of T-2 Toxin. Group: Biochemicals. Alternative Names: (3α,4 β,8α)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 8-(3-Methylbutanoate); 12,13-Epoxytrichothec-9-ene-3α,4 β,8α,15-tetrol 8-Isovalerate; Deacetyl HT 2 Toxin; T 2 Triol; Toxin T 2 Triol; Toxin T 3. Grades: Highly Purified. CAS No. 34114-98-2. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| T2 Toxin Triol | The 100 ppm acetonitrile solution of T2 Triol toxin, a kind of type-A trichothecene mycotoxin, could be used as standard solution. Synonyms: Scirpentriol; T-2 triol; Trichothec-9-ene-3-α,4-β,8-α,15-tetrol, 12,13-epoxy-, 8-isovalerate; T2 Triol Toxin; Toxin T-2 triol; Deacetyl-HT-2 toxin; 12,13-Epoxytrichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol 8-isovalerate; Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 8-(3-methylbutanoate), (3alpha,4beta,8alpha)-. Grade: ≥95%. CAS No. 97373-21-2. Molecular formula: C20H30O7. Mole weight: 382.45. | |
| T-3364366 | T-3364366 is a reversible, slow-binding, thienopyrimidinone delta-5 desaturase (D5D) inhibitor with IC50s of 1.9 nM and 2.1 nM in HepG2 and RLN-10 cells, respectively. T-3364366 exhibits potent D5D (IC500=19 nM) inhibitory activity and excellent selectivity away from delta-6 desaturase (D6D, IC50=6200 nM) and delta-9 desaturase (stearoyl-CoA desaturase, SCD,50 >10000 nM) in the enzymatic activity assay[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1356354-09-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-124346. | |
| T-3764518 | T-3764518 is a novel and potent stearoyl coenzyme A desaturase (SCD) inhibitor with an IC50 of 4.7 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1809151-56-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102045. | |
| T-3775440 hydrochloride | T-3775440 (hydrochloride) is an irreversible lysine-specific histone demethylase (LSD1) inhibitor with an IC50 value of 2.1 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1422535-52-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103085. | |
| T3-ATA (S-isomer) | T3-ATA S-isomer is the S-isomer of T3-ATA, which is the active form of the thyroid hormone. Uses: Scientific research. Category: Signaling pathways. CAS No. 2438721-48-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114271A. | |
| T3Inh-1 | T3Inh-1 is a potent and selective inhibitor of ppGalNAc-T3 (IC50=7 μM). T3Inh-1 reduces FGF23 hormone levels in both tissue cells and mice, without causing any toxic side effects. T3Inh-1 also prevents breast cancer cells. The enzyme ppGalNAc-T3 is implicated in at least two medically important pathways: cancer metastasis and stabilization of FGF23 (regulates phosphate levels in the bloodstream)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 50440-30-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125961. | |
| T-448 | T-448 is a specific, orally active, CNS-penetrant and irreversible inhibitor of lysine-specific demethylase 1 (LSD1, an H3K4 demethylase), with an IC50 of 22 nM. T-448 enhances H3K4 methylation in primary cultured rat neurons[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1597426-53-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122635A. | |
| T4 β-glucosyltransferase, Recombinant | In enzymology, a DNA beta-glucosyltransferase is an enzyme that catalyzes the chemical reaction in which a beta-D-glucosyl residue is transferred from UDP-glucose to an hydroxymethylcytosine residue in DNA. It is analogous to the enzyme DNA alpha-glucosyltransferase. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. T4-phage beta-glucosyltransferase, also known as udp glucose-dna ?-glucosyltransferase, (genbank accession no. np_049658) amino acids 1-351 (end) with c-terminal his-tag, mw=41.6 kda, expressed in e. coli. Applications: Useful for the differentiation of hydroxymethylcytosine (hmc) from methylcytosine in dna, via glucosylating hmc and protecting hmc from endonuclease cleavage. Group: Enzymes. Synonyms: T4 Beta-glucosyltransferase; DNA beta-glucosyltransferase; T4-HMC-beta-glucosyl transferase; T4-beta-glucosy. Purity: > 83% (SDS-PAGE). β-glucosyltransferase. Mole weight: mol wt 41.6 kDa. Storage: -70°C. Form: aqueous solution, Formulated in 200 mM imidazole and 20% glycerol. Source: E. coli. T4 Beta-glucosyltransferase; DNA beta-glucosyltransferase; T4-HMC-beta-glucosyl transferase; T4-beta-glucosyl transferase; T4 phage beta-glucosyltransferase; UDP glucose-DNA beta-glucosyltransferase; uridine diphosphoglucose-deoxyribonucleate beta-glucosyltransferase. Cat No: NATE-0773. | |
| T4 deoxyribonuclease II | Requires Mg2+. This phage T4 enzyme is involved in degradation of host DNA. The enzyme primarily catalyses nicking of the bottom strand of double stranded DNA between the first and second base pair to the right of a top-strand CCGC motif. Double-stranded breaks are produced 5- to 10-fold less frequently. It does not cleave the T4 native DNA, which contains 5-hydroxymethylcytosine instead of cytosine. Group: Enzymes. Synonyms: T4 endonuclease II; EndoII (ambiguous); denA (gene name). Enzyme Commission Number: EC 3.1.21.8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3578; T4 deoxyribonuclease II; EC 3.1.21.8; T4 endonuclease II; EndoII (ambiguous); denA (gene name). Cat No: EXWM-3578. | |
| T4 deoxyribonuclease IV | This phage T4 enzyme is involved in degradation of host DNA. The enzyme does not cleave double-stranded DNA or native T4 DNA, which contains 5-hydroxymethylcytosine instead of cytosine. Group: Enzymes. Synonyms: T4 endonuclease IV; EndoIV (ambiguous); denB (gene name). Enzyme Commission Number: EC 3.1.21.9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3579; T4 deoxyribonuclease IV; EC 3.1.21.9; T4 endonuclease IV; EndoIV (ambiguous); denB (gene name). Cat No: EXWM-3579. | |
| T4 DNA ligase | T4 DNA ligase is the product of gene 30 of phage T4. T4 DNA ligase catalyzes the repair of single-stranded nicks in duplex DNA and joins duplex DNA restriction fragments having either blunt or cohesive ends. T4 DNA ligase catalyze the sealing of adjacent 5-phosphate and 3--hydroxyl termini at single-stranded breaks in double-stranded DNA.T4 DNA ligase is an ATP-dependent ligase enzyme. T4 DNA ligase can be used in various biotechnological applications. T4 DNA ligase can join the ends of single-stranded DNA in the absence of any duplex DNA structure at the ligation site[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9015-85-4. Pack Sizes: 10 KU. Product ID: HY-P3005. | |
| T4 DNA Ligase | T4 DNA Ligase. T4 dna ligase catalyzes the formation of a phosphodiester bond between juxtaposed 5'-phosphate and 3'-hydroxyl termini in duplex dna or rna with blunt or cohesive end. the enzyme repairs single-strand nicks in duplex dna, rna or dna/rna hybrids but has no activity on single-strand nucleic acids. t4 dna ligase requires atp as a cofactor. Group: DNA Modifying Enzymes. Purity: 10KU; 20KU. Storage: Store at -20°C. Cat No: ME-4005. | |
| T-518 | T-518 is an orally active, BBB-penetrant and potent DFMO-based HDAC6 inhibitor with high selectivity (IC50 = 36 nM). T-518 improves axonal transport. T-518 ameliorates object recognition deficit. T-518 can be studied in research for Alzheimers disease and tauopathy[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2276680-91-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161307. | |
| T-5224 | T-5224 is a transcription factor c-Fos/activator protein (AP)-1 inhibitor with anti-inflammatory effects, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors. T-5224 inhibits the IL-1β-induced up-regulation of Mmp-3, Mmp-13 and Adamts-5 transcription[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 530141-72-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-12270. | |
| T-5224 | T-5224 is a selective inhibitor of transcription factor c-Fos / activator protein (AP)-1 with anti-inflammatory effects. T-5224 specifically inhibits the DNA binding activity of c-Fos/c-Jun and the IL-1β-induced up-regulation of Mmp-3, Mmp-13 and Adamts-5 transcription. Group: Inhibitors. CAS No. 530141-72-1. Pack Sizes: 5mg. Product ID: S8966. Formula: C29H27NO8. Smiles: C1CCC(C1)OC2=CC(=C(C=C2)C(=O)C3=CC(=C(C=C3)OCC4=CC5=C(C=C4)C(=O)NO5)CCC(=O)O)O. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| T5342126 | T-5342126 is a toll-like receptor 4 (TLR4) antagonist. It reduces LPS-induced production of nitric oxide (NO) in RAW 264.7 cells (IC50=27.8 μM), as well as decreases LPS-induced IL-8, TNF-α, and IL-6 production in isolated human whole blood (IC50s=110.5, 315.6, and 318.4 μM, respectively). T-5342126 (82 mg/kg) reduces ethanol intake and the abundance of ionized calcium-binding adapter molecule 1 (Iba1), a marker of microglial activation, in the central nucleus of the amygdala in ethanol-dependent mice. Uses: Scientific research. Category: Signaling pathways. CAS No. 956507-49-6. Pack Sizes: 1 mg (21.83 mM * 100 μL in Methyl acetate); 5 mg (21.83 mM * 500 μL in Methyl acetate); 10 mg (21.83 mM * 1 mL in Methyl acetate). Product ID: HY-123789. | |
| T 5601640 | T 5601640. Group: Biochemicals. Grades: Purified. CAS No. 924473-59-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| T6167923 | T6167923 is a selective inhibitor of MyD88-dependent signaling pathways. T6167923 directly binds to Toll/IL1 receptor (TIR) domain of MyD88 and disrupts MyD88 homodimeric formation. T6167923 inhibits NF-κB driven Staphylococcus enterotoxin AP (SEAP) activity, and improves anti-inflammatory activity with IC50s of 2.7 μM, 2.9 μM, 2.66 μM and 2.66 μM for IFN-γ, IL-1β, IL-6 and TNF-α, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2437475-16-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19744. | |
| T638 | T638 is a topoisomerase II (TOP2) inhibitor. T638 inhibits TOP2A activity with a IC50 of 0.7 uM. T638 strongly inhibits cancer cell growth[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2770585-67-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-164143. | |
| T7 Endonuclease I | T7 Endonuclease I. T7 endonuclease i is a junction-resolving enzyme of 149 amino acid residue, encoded by gene 3 of bacteriophage t7, existing as a stable dimer. not only does it selectively bind and cleave four-way dna (holliday) junctions with high specificity for branched structures in double-stranded dna, such as cruciform dna, but also it has a strong preference for cutting single-stranded dna. it requires metal ions such as magnesium for activity. this product is purified from e. coli expressing the recombinant t7 endonuclease i (t7ei) gene. Group: DNA Modifying Enzymes. Purity: 250U; 5*250U. Storage: Store at -20°C. Cat No: ME-4004. | |
| T7 Novispirin | T7 Novispirin is an antibacterial peptide. Synonyms: Lys-Asn-Leu-Arg-Arg-Ile-Thr-Arg-Lys-Ile-Ile-His-Ile-Ile-Lys-Lys-Tyr-Gly. Grade: >96%. Molecular formula: C103H184N34O22. Mole weight: 2250.82. | |
| T7 RNA Polymerase | T7 RNA Polymerase is a high yielding recombinant protein from Escherichia coli and is the workhorse enzyme for in vitro nucleic acid synthesis. Produced GMP compliant, the enzyme is tested extensively for the absence of unwanted contaminants, such as endo/exonucleases and RNases. The enzyme is supplied in liquid form in a standard or lyophilization-friendly formulation. The result is an enzyme with enhanced stability, ease of use and high performance. Applications: T7 rna polymerase is used in high-demand applications of molecular biology and therapeutic manufacturing. the major use of the enzyme is in the critical in vitro transcription (ivt) synthesis of mrna for next-generation therapeutics and vaccines. t7 rna polymerase is also used to produce radiolabeled rna probes, to produce rna for structural and catalytic studies, to construct sgrna for crispr research, to mediate expression control via anti-sense rna, and it is a key reagent for a variety of molecular diagnostic techniques. Category: Biochemical reagents. Grades: DMF. Product ID: PIPB-0793. Appearance: Clear and transparent liquid. Standard: Facility GMP. |  |
| T7 Tag Peptide | T7 Tag Peptide, an epitope tag composed of an 11-residue peptide encoded from the leader sequence of the T7 bacteriophage gene10, and serves as a tag in many expression vectors that is based on the very efficient T7 RNA polymerase expression system. Synonyms: Met-Ala-Ser-Met-Thr-Gly-Gly-Gln-Gln-Met-Gly; L-methionyl-L-alanyl-L-seryl-L-methionyl-(3xi)-L-threonyl-glycyl-glycyl-L-glutaminyl-L-glutaminyl-L-methionyl-glycine. Grade: ≥95%. Molecular formula: C41H71N13O16S3. Mole weight: 1098.27. | |
| T807 | T807 a novel tau positron emission tomography (PET) tracer. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AV-1451. CAS No. 1415379-56-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101184. | |
| T808 | T808 is a selective tau protein-targeting ligand. T808 can be used to synthesize [18F]-T808, a highly selective tau protein positron emission tomography (PET) tracer. T808 can also be used to synthesize [3H]-T808, a marker for in vitro experiments. T808 can be used for the research of alzheimers disease[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1320211-61-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101185. | |
| T863 | T863 is an orally active, selective and potent DGAT1 (acyl-CoA:diacylglycerol acyltransferase 1) inhibitor with an IC50 of 15 nM. T863 has no inhibitory activity against human MGAT3, human DGAT2, or human MGAT2. T863 interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 701232-20-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-32219. | |
| T 98475 | T 98475. Group: Biochemicals. Grades: Purified. CAS No. 199119-18-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ta-10W Alloy Powder | Ta-10W Alloy Powder. | |
| TA11 Spherical Titanium Alloy Powder | TA11 alloy is a type of α type titanium alloy, containing α stable element Al and isomorphism β stable elements Mo and V. This alloy has a higher elastic modulus and lower density, so its specific stiffness is the highest among industrial titanium alloys. The room temperature tensile strength of this alloy is comparable to that of TC4 alloy, but its high-temperature strength and creep resistance are superior to TC4 alloy. | |
| Ta-12W Alloy Powder | With the increase of tungsten content, the high-temperature strength of the alloy also increases, and the plasticity of the alloy decreases. | |
| TA15 Spherical Titanium Alloy Powder | TA15 alloy is a titanium alloy containing the refractory metal zirconium. Zr element is widely added as a neutral element to titanium alloys. Compared with other titanium alloy additives such as Fe, Mo, Cr, etc., Zr element has a weaker strengthening effect on titanium alloys at room temperature, while its strengthening effect is more obvious at high temperature. Therefore, it is often used to add to high-strength titanium alloys. The Zr element content can not only improve the high-temperature tensile strength, but also simultaneously enhance the high-temperature resistance and creep performance. | |
| Ta-15W Alloy Powder | Ta-15W alloy powder is a powder material made by alloying tantalum (Ta) and tungsten (W). | |
| TA1 Spherical Pure Titanium Powder | TA1 is a pure titanium material, which not only has certain mechanical properties and good biocompatibility, but also has excellent corrosion resistance. Pure titanium products have broad application prospects in chemical, shipping, medical and other fields. | |
| Ta-2.5W Alloy Powder | Ta-2.5W Alloy Powder. Purity: 99.9%+. | |
| Ta-25W Alloy Powder | With the increase of tungsten content, the high-temperature strength of the alloy also increases, and the plasticity of the alloy decreases. | |
| Ta2AlC MAX phase ceramic material | Ta2AlC MAX phase ceramic material. Purity: ≥99%. | |
| Ta2C MXene quantum dots | Ta2C MXene quantum dots. Purity: 0.99. | |
| TA-3037A | TA-3037A is a glutathione S-transferase inhibitor isolated from the fermentation broth of Streptomyces sp. TA-3037. Synonyms: TA 3037A; (Z)-3,4-Dihydro-2-oxo-3-(phenylmethylene)-2H-1,4-benzoxazine-5-carboxylic acid. CAS No. 143651-44-9. Molecular formula: C16H11NO4. Mole weight: 281.26. | |
| TA-316 | TA-3166 (Megakaryocytes/platelets inducing agent) is a novel chemically synthesized c-MPL agonist (CMA) and thrombopoietin (TPO) receptor agonist. TA-316 enhances ex vivo platelet generation from human-induced pluripotent stem (iPS) cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Megakaryocytes/platelets inducing agent. CAS No. 1429321-13-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112486. | |
| Ta4AlC3 (MAX) Phase Ceramic Material | Ta4AlC3 (MAX) Phase Ceramic Material. CAS No. 12070-06-3. Purity: ≥90%. | |
| Ta4AlC3 MAX phase material | Excellent Mxene precursor can be processed by HF or HCl+LiF to obtain MXene. Purity: 0.99. | |
| Ta4C3 MXene quantum dots | Ta4C3 MXene quantum dots. Purity: 80-93wt%. | |
| Ta4C3 single layer dispersion | Ta4C3 single layer dispersion. Purity: 80-93wt%. | |
| Ta4C3 single layer powder | Ta4C3 single layer powder. Purity: 80-93wt%. | |
| Ta4C3Tx (MXene) Multilayer Nanosheet | Ta4C3Tx (MXene) Multilayer Nanosheet. CAS No. 12070-06-3. Purity: ≥85%. | |
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