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| Product | Description | |
|---|---|---|
| T-00127_HEV1 | T-00127_HEV1 is a phosphatidylinositol 4-kinase III beta ( PI4KB ) inhibitor with an IC 50 of 60 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 900874-91-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108313. |  |
| T0070907 | T0070907 is a potent PPAR? antagonist with a Ki of 1 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 313516-66-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13202. | |
| T0070907 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| T0070907 | T0070907 was identified as a potent and selective PPARgamma antagonist. T0070907 blocked PPARgamma function in both cell-based reporter gene and adipocyte differentiation assays. T0070907 is a novel tool for the study of PPARgamma/RXRalpha heterodimer function. Synonyms: T-0070907; T 0070907. Grades: 0.98. CAS No. 313516-66-4. Molecular formula: C12H8ClN3O3. Mole weight: 277.66. |  |
| T 0070907 | T 0070907. Group: Biochemicals. Grades: Purified. CAS No. 313516-66-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| T0070907 (2-Chloro-5-nitro-N-4-pyridinyl-benzamide) | T0070907 is a potent and selective antagonist of the human PPARy (IC50=1nm). T0070907 suppresses breast cancer cell proliferation and motility via both PPARy-dependent and -independent mechanisms. Group: Biochemicals. Grades: Highly Purified. CAS No. 313516-66-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| T01-1 | T01-1 is an anticancer agent (camptothecin derivative) with good anti-proliferative activity[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KL610023. CAS No. 2356229-14-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148185. | |
| T 0156 hydrochloride | T 0156 hydrochloride is a potent and selective inhibitor of phosphodiesterase type 5 (PDE5). T 0156 exhibits higher selectivity than sildenafil (IC50 = 0.23, 56 and > 63000 nM for T 0156 and 3.6, 29 and > 270 nM for sildenafil at PDE5, PDE6 and PDEs 1 - 4 respectively). Synonyms: 2,7-Naphthyridine-3-carboxylic acid, 1,2-dihydro-2-[(2-methyl-4-pyridinyl)methyl]-1-oxo-8-(2-pyrimidinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-, methyl ester, hydrochloride (1:1); 2,7-Naphthyridine-3-carboxylic acid, 1,2-dihydro-2-[(2-methyl-4-pyridinyl)methyl]-1-oxo-8-(2-pyrimidinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-, methyl ester, monohydrochloride; Methyl 1,2-dihydro-2-[(2-methyl-4-pyridinyl)methyl]-1-oxo-8-(2-pyrimidinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-2,7-naphthyridine-3-carboxylate hydrochloride (1:1); T0156; T-0156. Grades: ≥99% by HPLC. CAS No. 324572-93-2. Molecular formula: C31H29N5O7.HCl. Mole weight: 620.06. | |
| T-0201 | T-0201 has been found to be an Endothelin A receptor antagonist that could be used as as anti-ischaemic agent and was once studied in heart failure and pulmonary hypertension. Synonyms: T-0201, T0201, T 0201, TA 0201, TA0201, TA-0201; N-(6-(2-((5-bromopyrimidin-2-yl)oxy)ethoxy)-5-(p-tolyl)pyrimidin-4-yl)-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide. Grades: 98%. CAS No. 169679-53-2. Molecular formula: C27H28BrN5O5S. Mole weight: 614.52. | |
| T-0201 Sodium | The sodium salt form of T-0201 which has been found to be an Endothelin A receptor antagonist that could be used as as anti-ischaemic agent and was once studied in heart failure and pulmonary hypertension. Synonyms: T-0201 Sodium; T0201 Sodium; T 0201 Sodium; N-(6-(2-((5-bromopyrimidin-2-yl)oxy)ethoxy)-5-(p-tolyl)pyrimidin-4-yl)-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide sodium salt. Grades: 98%. CAS No. 188307-16-6. Molecular formula: C27H28BrN5NaO5S+. Mole weight: 637.51. | |
| T025 | T025 is an orally active and highly potent inhibitor of Cdc2-like kinase (CLKs), with Kd values of 4.8, 0.096, 6.5, 0.61, 0.074, 1.5 and 32 nM for CLK1, CLK2, CLK3, CLK4, DYRK1A, DYRK1B and DYRK2, respectively. T025 induces caspase-3/7-mediated cell apoptosis. T025 reduces CLK-dependent phosphorylation. T025 exerts anti-proliferative activities in both hematological and solid cancer cell lines (IC50 values: 30-300 nM). T025 has an anti-tumor efficiency, mainly for MYC-driven disease research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2407433-00-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112296. | |
| T07C4.4 | T07C4.4 is an antibacterial peptide isolated from Leptodactylus syphax. Synonyms: Met-Thr-Arg-Ile-Leu-Pro-Cys-Leu-Phe-Leu-Val-Leu-Leu-Ala-Ala-Ala-Pro-Leu-Leu-Ala-Asn-Pro-Ala-Asn-Pro-Leu-Asn-Leu-Lys-Lys-His-His-Gly-Val-Phe. Grades: >97%. | |
| T0901317 | ?98%. Group: Fluorescence/luminescence spectroscopy. | |
| T0901317 | T0901317 is an orally active and highly selective LXR agonist with an EC50 of 20 nM for LXR?[1]. T0901317 activates FXR with an EC50 of 5 ?M[2]. T0901317 is ROR? and ROR? dual inverse agonist with Ki values of 132 nM and 51 nM, respectively[3]. T0901317 induces apoptosis and inhibits the development of atherosclerosis in low-density lipoprotein (LDL) receptor-deficient mice[4][5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 293754-55-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10626. | |
| T0901317 | T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively. T0901317 induces apoptosis and inhibits the development of atherosclerosis in low-density lipoprotein (LDL) receptor-deficient mice. Synonyms: T 0901317; T-0901317; TO-901317; TO901317; N- (2, 2, 2-trifluoroethyl) -N-[4-[2, 2, 2-trifluoro-1-hydroxy-1- (trifluoromethyl) ethyl]phenyl]benzenesulfonamide; T-1317. Grades: >98%. CAS No. 293754-55-9. Molecular formula: C17H12F9NO3S. Mole weight: 481.33. | |
| T 0901317 | T 0901317. Group: Biochemicals. Grades: Purified. CAS No. 293754-55-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| T 0901317 (T-0901317, T0901317) | T 0901317 (T-0901317, T0901317). Group: Biochemicals. Alternative Names: N-[4- (1, 1, 1, 3, 3, 3-hexafluoro-2-hydroxypropan-2-yl) phenyl]-N- (2, 2, 2-trifluoroethyl) benzenesulfonamide. Grades: Highly Purified. CAS No. 293754-55-9. Pack Sizes: 50mg. Molecular Formula: C17H12F9NO3 , Molecular Weight: 481.3. US Biological Life Sciences. | Worldwide |
| T-1095 | T-1095, with potential antidiabetic effect, is an inhibitor of renal Na+-glucose cotransporters that may provide a novel way to treating diabetes. Synonyms: [(2R,3S,4S,5R,6S)-6-[2-[3-(1-benzofuran-5-yl)propanoyl]-3-hydroxy-5-methylphenoxy]-3,4,5-trihydroxyoxan-2-yl]methyl methyl carbonate; T 1095; T-1095. Grades: >98%. CAS No. 209746-59-8. Molecular formula: C26H28O11. Mole weight: 516.49. | |
| T16Ainh - A01 | T16Ainh - A01. Group: Biochemicals. Grades: Purified. CAS No. 552309-42-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| T16Ainh-A01 | T16Ainh-A01 is a selective inhibitor of Ca2+-dependent Cl- channel (CaCC) transmembrane protein 16A (TMEM16A) (IC50 = 1.8 μM in A253 salivary gland epithelial cells). T16Ainh-A01 inhibits EGF-induced increases in CaCC currents, and blocks proliferation of pancreatic cancer and squamous carcinoma cells in culture. Synonyms: 2-[(5-Ethyl-1,6-dihydro-4-methyl-6-oxo-2-pyrimidinyl)thio]-N-[4-(4-methoxyphenyl)-2-thiazolyl]acetamide. Grades: ≥98% by HPLC. CAS No. 552309-42-9. Molecular formula: C19H20N4O3S2. Mole weight: 416.52. | |
| T16Ainh-A01 | T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 μM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 552309-42-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100612. | |
| T16Ainh-A01 | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| T 1776Na | T 1776Na is an selective inhibitor of plasminogen activator inhibitor-1 (PAI-1). Grades: 99%. CAS No. 1202075-60-2. Molecular formula: C25H18NNaO4. Mole weight: 419.4. | |
| T1AM | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| T 2588G | T 2588G. Group: Biochemicals. Alternative Names: (Z)-2-Amino-a-(methoxyimino)-N-(2-oxoethyl)-4-thiazoleacetamide; THR 221V. Grades: Highly Purified. CAS No. 104301-63-5. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C8H10N4O3S. US Biological Life Sciences. | Worldwide |
| T 2588G Sodium Bisulfite adduct | T 2588G Sodium Bisulfite adduct. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS003255. Format: Neat. | |
| T-26c | T-26c is a selective matrix metalloproteinase-13 (MMP-13) inhibitor with IC50 value of 0.0069 nM. It inhibits IL-1β- and oncostatin M-induced collagen degradation in bovine nasal septum cartilage explants by 87.4% when used at a concentration of 0.1 μM. T-26c is used for the treatment of osteroarthritis and rhuematoid arthritis. Synonyms: 4-[[2-[(3-methoxyphenyl)methylcarbamoyl]-4-oxo-3H-thieno[2,3-d]pyrimidin-5-yl]methoxymethyl]benzoic acid. Grades: ≥98%. CAS No. 869296-13-9. Molecular formula: C24H21N3O6S. Mole weight: 479.5. | |
| T-26c | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| T 26c disodium salt | T 26c disodium salt is a potent, selective and orally available MMP13 inhibitor (IC50 = 6.9 pM) with >2600-fold selectivity for MMP13 over related MMPs. T 26c inhibits degradation of bovine nasal septum cartilage explants in vitro. Synonyms: Disodium 4-[[[[2-[[[[3- (Methyloxy) phenyl]methyl]amino]carbonyl]-4-oxo-3, 4-dihydrothieno[2, 3-d]pyrimidin-5-yl]methyl]oxy]methyl]benzoate. Grades: ≥98% by HPLC. CAS No. 869298-22-6. Molecular formula: C24H19N3Na2O6S. Mole weight: 523.47. | |
| T2AA | T2AA is a proliferating cell nuclear antigen (PCNA) inhibitor. T2AA inhibits PCNA/PIP-box peptide interaction (IC50 ~1 μM), leading to the suppression of DNA replication stress by stalling DNA replication forks. T2AA inhibits the interaction of PCNA with DNA polymerase δ and arrests cell growth in S-phase. Synonyms: (βS)-β-Amino-4-(4-hydroxyphenoxy)-3,5-diiodobenzenpropanol; 4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol. Grades: ≥98% by HPLC. CAS No. 1380782-27-3. Molecular formula: C15H15I2NO3. Mole weight: 511.09. | |
| T2AA | T2AA is a monoubiquitinated proliferating cell nuclear antigen (PCNA) inhibitor that prevents DNA repair, increases double-strand break (DSB) formation and promotes necroptosis and cell cycle arrest in G1 phase[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1380782-27-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110111. | |
| T2AA hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| T2-induced deoxynucleotide kinase | dTMP and dAMP can act as acceptors; dATP can act as donor. Group: Enzymes. Enzyme Commission Number: EC 2.7.4.12. CAS No. 37278-99-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3193; T2-induced deoxynucleotide kinase; EC 2.7.4.12; 37278-99-2. Cat No: EXWM-3193. |  |
| t2t | t2t. Group: Organic light-emitting diode (oled) materials. CAS No. 1201800-83-0. Product ID: 2,4,6-tris(3-phenylphenyl)-1,3,5-triazine. Molecular formula: 537.6g/mol. Mole weight: C39H27N3. C1=CC=C (C=C1)C2=CC (=CC=C2)C3=NC (=NC (=N3)C4=CC=CC (=C4)C5=CC=CC=C5)C6=CC=CC (=C6)C7=CC=CC=C7. InChI=1S/C39H27N3/c1-4-13-28 (14-5-1)31-19-10-22-34 (25-31)37-40-38 (35-23-11-20-32 (26-35)29-15-6-2-7-16-29)42-39 (41-37)36-24-12-21-33 (27-36)30-17-8-3-9-18-30/h1-27H. MMNNWKCYXNXWBG-UHFFFAOYSA-N. |  |
| T-2 Tetraol | It is a kind of nature type-A trichothecene mycotoxin, could be used as a reference standard in quantitative analysis of food stuffs. Synonyms: Trichothec-9-ene-3α,4β,8α,15-tetrol, 12,13-epoxy-; (3α,4β,8α)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol; T 2 toxin tetraol; Toxin T 2 tetraol; Toxin T 4. Grades: ≥95%. CAS No. 34114-99-3. Molecular formula: C15H22O6. Mole weight: 298.33. | |
| T-2 Toxin | T-2 toxin is a common trichothecene mycotoxin produced by Fusarium species, which can infect grain crops causing alimentary toxic aleukia in humans and animals. It triggers a ribotoxic response through its high binding affinity to peptidyl transferase, which is an integral part of the 60S ribosomal subunit, resulting in activation of JNK/p38 MAPKs, interferes with the metabolism of membrane phospholipids, and increases liver lipid peroxides.1 T-2 toxin is highly cytotoxic to macrophages, inducing apoptosis in primary porcine alveolar macrophage cells with an IC50 value of 19.47 nM. At 3 nM it decreases the production of inflammatory mediators (IL-1 β, TNFα, and nitric oxide), TLR4, and TLR2/6 agonists.2. Group: Biochemicals. Alternative Names: (3α,4 β,8α)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 4,15-Diacetate 8-(3-Methylbutanoate); 12,13-Epoxytrichothec-9-ene-3α,4 β,8α,15-tetrol 4,15-Diacetate 8-Isovalerate; 4 β,15-Diacetoxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-en-3α-ol; 8α-(3-Methylbutyryloxy)-4 β,15-diacetoxyscirp-9-en-3α-ol; Fusariotoxin T 2; Insariotoxin; Mycotoxin T 2; NSC 138780; T 2; T 2 mycotoxin; T-2 Lienomycin; Toxin T 2. Grades: Highly Purified. CAS No. 21259-20-1. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| T2 toxin triol | T2 toxin triol. Group: Biochemicals. Alternative Names: Toxin T 3; (3a,4b,8a)-12,13-Epoxy-trichothec-9-ene-3,4,8,15-tetrol 8-(3-methylbutanoate); Deacetyl HT 2 toxin. Grades: Highly Purified. CAS No. 34114-98-2,97373-21-2. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C20H30O7. US Biological Life Sciences. | Worldwide |
| T-2 Toxin Triol | T-2 Toxin Triol is a type-A trichothecene mycotoxin produced by Fusarium, itself a metabolite of T-2 Toxin. Group: Biochemicals. Alternative Names: (3α,4 β,8α)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 8-(3-Methylbutanoate); 12,13-Epoxytrichothec-9-ene-3α,4 β,8α,15-tetrol 8-Isovalerate; Deacetyl HT 2 Toxin; T 2 Triol; Toxin T 2 Triol; Toxin T 3. Grades: Highly Purified. CAS No. 34114-98-2. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| T2 Toxin Triol | The 100 ppm acetonitrile solution of T2 Triol toxin, a kind of type-A trichothecene mycotoxin, could be used as standard solution. Synonyms: Scirpentriol; T-2 triol; Trichothec-9-ene-3-α,4-β,8-α,15-tetrol, 12,13-epoxy-, 8-isovalerate; T2 Triol Toxin; Toxin T-2 triol; Deacetyl-HT-2 toxin; 12,13-Epoxytrichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol 8-isovalerate; Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 8-(3-methylbutanoate), (3alpha,4beta,8alpha)-. Grades: ≥95%. CAS No. 97373-21-2. Molecular formula: C20H30O7. Mole weight: 382.45. | |
| T-2 Triol | T-2 Triol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 12,13-epoxy-3-alpha,4-beta,8-alpha,15-tetrahydroxy-trichothec-9-en8-isov;12,13-epoxytrichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol8-isovalerate;3-alpha,4-beta,15-trihydroxy-8-alpha-(3-methylbutyryloxy)-12,13-epoxytrichot;4-beta,8-alpha,15-tetrol,12,13. Product Category: Heterocyclic Organic Compound. CAS No. 34114-98-2. Molecular formula: C20H30O7. Mole weight: 382.45. Product ID: ACM34114982. Alfa Chemistry ISO 9001:2015 Certified. |  |
| T-3364366 | T-3364366 is a reversible and slow-binding Delta-5 desaturase (D5D) inhibitor. Ki is less than 2.7 nM and a dissociation half-life is more than 2.0 h. D5D is an attractive drug target for inflammatory-related. Uses: Inflammatory-related. Synonyms: T-3364366, T 3364366, T3364366; N-(2-((4-oxo-3-(4-(2,2,2-trifluoroethoxy)phenyl)-3,4-dihydrothieno[3,4-d]pyrimidin-2-yl)thio)ethyl)acetamide. Grades: 98%. CAS No. 1356354-09-0. Molecular formula: C18H16F3N3O3S2. Mole weight: 443.46. | |
| T338C Src-IN-1 | T338C Src-IN-1, a pyrazolopyrimidine detivative, has been found effective T338C inhibition and could be significant for determing the effect of kinases by Chemical genetics. Uses: T338c src-in-1 has been found effective t338c inhibition and could be significant for determing the effect of kinases by chemical genetics. Synonyms: T338C Src-IN-1; CHEMBL2216823; SCHEMBL7509503; BDBM50403061; HY-16905; HY 16905; HY16905. Grades: 98%. CAS No. 1351926-90-3. Molecular formula: C17H20N6O2S. Mole weight: 372.44. | |
| T338C Src-IN-2 | T338C Src-IN-2, a pyrazolopyrimidine detivative, has been found to be a c-Src T338C kinase inhibitor and could be significant for determing the effect of kinases by Chemical genetics. IC50: 57 nM and 19 nM for T338C and V323S respectively. Uses: T338c src-in-2 has been found to be a c-src t338c kinase inhibitor and could be significant for determing the effect of kinases by chemical genetics. ic50: 57 nm and 19 nm for t338c and v323s respectively. Synonyms: T338C Src-IN-2; SCHEMBL7515000; HY-16906; HY 16906; HY16906. Grades: 98%. CAS No. 1351927-00-8. Molecular formula: C17H18FN5O. Mole weight: 327.36. | |
| T-3775440 hydrochloride | T-3775440 HCl is an irreversible and selective LSD1 inhibitor. Synonyms: T-3775440 HCl; N-[4-[ (1S, 2R) -2- (cyclopropylmethylamino) cyclopropyl]phenyl]-1-methylpyrazole-4-carboxamide hydrochloride. CAS No. 1422535-52-1. Molecular formula: C18H23ClN4O. Mole weight: 346.85. | |
| T3MG | T3MG is a selective inhibitor of excitatory amino acid transporters GLT-1, EAAT2, and EAAT4(IC50 values are 90, 109, 1600 and 1080 μM for EAAT2, EAAT4, EAAT1 and EAAT3 respectively). Synonyms: (2R,3S)-2-amino-3-methylpentanedioic acid; (±)-threo-3-Methylglutamic acid; 3MG; threo-3-Methylglutamate. Grades: ≥98% by HPLC. CAS No. 63088-04-0. Molecular formula: C6H11NO4. Mole weight: 161.16. | |
| T4 Beta-glucosyltransferase | recombinant, expressed in E. coli, ?83% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| T4 β-glucosyltransferase, Recombinant | In enzymology, a DNA beta-glucosyltransferase is an enzyme that catalyzes the chemical reaction in which a beta-D-glucosyl residue is transferred from UDP-glucose to an hydroxymethylcytosine residue in DNA. It is analogous to the enzyme DNA alpha-glucosyltransferase. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. T4-phage beta-glucosyltransferase, also known as udp glucose-dna ?-glucosyltransferase, (genbank accession no. np_049658) amino acids 1-351 (end) with c-terminal his-tag, mw=41.6 kda, expressed in e. coli. Applications: Useful for the differentiation of hydroxymethylcytosine (hmc) from methylcytosine in dna, via glucosylating hmc and protecting hmc from endonuclease cleavage. Group: Enzymes. Synonyms: T4 Beta-glucosyltransferase; DNA beta-glucosyltransferase; T4-HMC-beta-glucosyl transferase; T4-beta-glucosy. Purity: > 83% (SDS-PAGE). β-glucosyltransferase. Mole weight: mol wt 41.6 kDa. Storage: -70°C. Form: aqueous solution, Formulated in 200 mM imidazole and 20% glycerol. Source: E. coli. T4 Beta-glucosyltransferase; DNA beta-glucosyltransferase; T4-HMC-beta-glucosyl transferase; T4-beta-glucosyl transferase; T4 phage beta-glucosyltransferase; UDP glucose-DNA beta-glucosyltransferase; uridine diphosphoglucose-deoxyribonucleate beta-glucosyltransferase. Cat No: NATE-0773. | |
| t4CzIPN | t4CzIPN. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,4,5,6-Tetrakis[3,6-bis(1,1-dimethylethyl)-9H-carbazol-9-yl]- 1,3-Benzenedicarbonitrile. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1630263-99-8. Molecular formula: C88H96N6. Mole weight: 1237.74 g/mol. Product ID: ACM1630263998-2. Alfa Chemistry ISO 9001:2015 Certified. | |
| T4 deoxyribonuclease II | Requires Mg2+. This phage T4 enzyme is involved in degradation of host DNA. The enzyme primarily catalyses nicking of the bottom strand of double stranded DNA between the first and second base pair to the right of a top-strand CCGC motif. Double-stranded breaks are produced 5- to 10-fold less frequently. It does not cleave the T4 native DNA, which contains 5-hydroxymethylcytosine instead of cytosine. Group: Enzymes. Synonyms: T4 endonuclease II; EndoII (ambiguous); denA (gene name). Enzyme Commission Number: EC 3.1.21.8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3578; T4 deoxyribonuclease II; EC 3.1.21.8; T4 endonuclease II; EndoII (ambiguous); denA (gene name). Cat No: EXWM-3578. | |
| T4 deoxyribonuclease IV | This phage T4 enzyme is involved in degradation of host DNA. The enzyme does not cleave double-stranded DNA or native T4 DNA, which contains 5-hydroxymethylcytosine instead of cytosine. Group: Enzymes. Synonyms: T4 endonuclease IV; EndoIV (ambiguous); denB (gene name). Enzyme Commission Number: EC 3.1.21.9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3579; T4 deoxyribonuclease IV; EC 3.1.21.9; T4 endonuclease IV; EndoIV (ambiguous); denB (gene name). Cat No: EXWM-3579. | |
| T4 DNA Ligase | T4 DNA Ligase. T4 dna ligase catalyzes the formation of a phosphodiester bond between juxtaposed 5'-phosphate and 3'-hydroxyl termini in duplex dna or rna with blunt or cohesive end. the enzyme repairs single-strand nicks in duplex dna, rna or dna/rna hybrids but has no activity on single-strand nucleic acids. t4 dna ligase requires atp as a cofactor. Group: DNA Modifying Enzymes. Purity: 10KU; 20KU. Storage: Store at -20°C. Cat No: ME-4005. | |
| T-518 | T-518 is an orally active, BBB-penetrant and potent DFMO-based HDAC6 inhibitor with high selectivity (IC50 = 36 nM). T-518 improves axonal transport. T-518 ameliorates object recognition deficit. T-518 can be studied in research for Alzheimers disease and tauopathy[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2276680-91-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161307. | |
| T-5224 | T-5224 is a selective inhibitor of c-Fos/activator protein-1. T-5224 ameliorates liver injury and improves survival through decreasing production of proinflammatory cytokines and chemokines in endotoxemic mice. T-5224 has been investigated in phase II human clinical trials. T-5224 may be a promising new treatment for septic kidney injury. Activator protein 1 (AP-1) is a pivotal transcription factor that regulates a wide range of cellular processes including proliferation, apoptosis, differentiation, survival, cell migration, and transformation. Accumulating evidence supports that AP-1 plays an important role in several severe disorders including cancer, fibrosis, and organ injury, as well as inflammatory disorders such as asthma, psoriasis, and rheumatoid arthritis. Synonyms: T5224; T 5224. Grades: >98%. CAS No. 530141-72-1. Molecular formula: C29H27NO8. Mole weight: 517.53. | |
| T-5224 | T-5224 is a transcription factor c-Fos/activator protein (AP)-1 inhibitor with anti-inflammatory effects, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors. T-5224 inhibits the IL-1β-induced up-regulation of Mmp-3, Mmp-13 and Adamts-5 transcription [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 530141-72-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12270. | |
| T5342126 | T-5342126 is a toll-like receptor 4 (TLR4) antagonist. It reduces LPS-induced production of nitric oxide (NO) in RAW 264.7 cells ( IC 50 =27.8 μM), as well as decreases LPS-induced IL-8, TNF-α, and IL-6 production in isolated human whole blood ( IC 50 s=110.5, 315.6, and 318.4 μM, respectively). T-5342126 (82 mg/kg) reduces ethanol intake and the abundance of ionized calcium-binding adapter molecule 1 (Iba1), a marker of microglial activation, in the central nucleus of the amygdala in ethanol-dependent mice. Uses: Scientific research. Group: Signaling pathways. CAS No. 956507-49-6. Pack Sizes: 1 mg (21.83 mM * 100 μL in Methyl acetate); 5 mg (21.83 mM * 500 μL in Methyl acetate); 10 mg (21.83 mM * 1 mL in Methyl acetate). Product ID: HY-123789. | |
| T 5601640 | T 5601640. Group: Biochemicals. Grades: Purified. CAS No. 924473-59-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| T56-LIMKi | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| T56-LIMKi | T56-LIMKi is a selective inhibitor of LIMK2 that reduces phosphorylated cofilin and inhibits the growth of Panc-1 cells with an IC50 of 35.2 μM. Synonyms: 3-methyl-N-[3-[[3- (trifluoromethyl) phenyl]carbamoyl]phenyl]-1, 2-oxazole-5-carboxamide; 3-methyl-N- (3- ( (3- (trifluoromethyl) phenyl) carbamoyl) phenyl) isoxazole-5-carboxamide ; T-5601640; T 5601640; T5601640; T56LIMKi; T56 LIMKi; T56-LIMKi. CAS No. 924473-59-6. Molecular formula: C19H14F3N3O3. Mole weight: 389.33. | |
| T6167923 | T6167923 is a selective inhibitor of MyD88-dependent signaling pathways. T6167923 directly binds to Toll/IL1 receptor (TIR) domain of MyD88 and disrupts MyD88 homodimeric formation. T6167923 inhibits NF-?B driven Staphylococcus enterotoxin AP (SEAP) activity, and improves anti-inflammatory activity with IC50s of 2.7 ?M, 2.9 ?M, 2.66 ?M and 2.66 ?M for IFN-?, IL-1?, IL-6 and TNF-?, respectively[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2437475-16-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19744. | |
| T62 | ?98% (HPLC), crystalline. Group: Fluorescence/luminescence spectroscopy. | |
| T7 Endonuclease I | T7 Endonuclease I. T7 endonuclease i is a junction-resolving enzyme of 149 amino acid residue, encoded by gene 3 of bacteriophage t7, existing as a stable dimer. not only does it selectively bind and cleave four-way dna (holliday) junctions with high specificity for branched structures in double-stranded dna, such as cruciform dna, but also it has a strong preference for cutting single-stranded dna. it requires metal ions such as magnesium for activity. this product is purified from e. coli expressing the recombinant t7 endonuclease i (t7ei) gene. Group: DNA Modifying Enzymes. Purity: 250U; 5*250U. Storage: Store at -20°C. Cat No: ME-4004. | |
| T7 Novispirin | T7 Novispirin is an antibacterial peptide. Synonyms: Lys-Asn-Leu-Arg-Arg-Ile-Thr-Arg-Lys-Ile-Ile-His-Ile-Ile-Lys-Lys-Tyr-Gly. Grades: >96%. Molecular formula: C103H184N34O22. Mole weight: 2250.82. | |
| T7 RNA polymerase | T7 RNA polymerase is a polymerase expressed by Escherichia coli from the RNA polymerase gene of T7 bacteriophage. T7 RNA polymerase is highly specific and involved in in vitro transcription (IVT) of mRNA. In the presence of Mg 2+ , T7 RNA polymerase only uses the single-stranded or double-stranded DNA containing the T7 promoter sequence as a template, and uses NTP as a substrate to synthesize RNA complementary to the single-stranded DNA downstream of the promoter [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9014-24-8. Pack Sizes: 1 KU; 5 KU. Product ID: HY-E70090. | |
| T7 Tag Peptide | T7 Tag Peptide is a protein tag derived from the N-terminal 11 residues of the major T7 capsid protein, gp 10. T7 Tag Peptide can be used in different immunoassays as well as affinity purification [1]. Uses: Scientific research. Group: Peptides. CAS No. 245445-88-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0327. | |
| T7 Tag Peptide | T7 Tag Peptide, an epitope tag composed of an 11-residue peptide encoded from the leader sequence of the T7 bacteriophage gene10, and serves as a tag in many expression vectors that is based on the very efficient T7 RNA polymerase expression system. Synonyms: Met-Ala-Ser-Met-Thr-Gly-Gly-Gln-Gln-Met-Gly; L-methionyl-L-alanyl-L-seryl-L-methionyl-(3xi)-L-threonyl-glycyl-glycyl-L-glutaminyl-L-glutaminyl-L-methionyl-glycine. Grades: ≥95%. Molecular formula: C41H71N13O16S3. Mole weight: 1098.27. | |
| T807 | T807, also known as 18F-AV-1451, is a novel tau positron emission tomography (PET) tracer. Synonyms: 7-(6-fluoropyridin-3-yl)-5H-pyrido[4,3-b]indole; (18)AV-1451; (18F)1451; (18F)AV-1451; (18F)T807 compound; (F-18)-AV-1451; 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole; AV-1451; AV1451; F-18-AV-1451; T-807; T807 compound. CAS No. 1415379-56-4. Molecular formula: C16H10FN3. Mole weight: 263.27. | |
| T807 | T807 a novel tau positron emission tomography (PET) tracer. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AV-1451. CAS No. 1415379-56-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101184. | |
| T817 | T817 is a neuroprotectant. It inhibits oxidative stress and nitric oxide-induced neurotoxicity and acts as a neurotrophic factor. It is a candidate therapeutic agent for Alzheimer's disease. It protects against MPTP-induced neurotoxicity by blocking lipid peroxidation in the SNc. It may be useful for treating neurodegenerative disorders related to oxidative stress, such as Parkinson's disease. It was developed by Toyama Chemical and Fujifilm group together. It is in the clinical phase II. Uses: T817 is a candidate therapeutic agent for alzheimer's disease. it may be useful for treating neurodegenerative disorders related to oxidative stress, such as parkinson's disease. Synonyms: T-817; T 817; Edonerpic; 1-(3-(2-(Benzo[b]thiophen-5-yl)ethoxy)propyl)azetidin-3-ol. Grades: 98%. CAS No. 519187-23-6. Molecular formula: C16H21NO2S. Mole weight: 291.41. | |
| T863 | T863 is an orally active, selective and potent DGAT1 (acyl-CoA:diacylglycerol acyltransferase 1) inhibitor with an IC50 of 15 nM. T863 has no inhibitory activity against human MGAT3, human DGAT2, or human MGAT2. T863 interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 701232-20-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-32219. | |
| T863 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
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