A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
S07-2010 is a potent pan-AKR1C (aldo-keto reductase family 1 member C) inhibitor, with IC50 values of 0.19, 0.36, 0.47, and 0.73 μM for AKR1C3, AKR1C4, AKR1C1 and AKR1C2, respectively. S07-2010 induces apoptosis in A549/DDP cells. S07-2010 strengthens the cytotoxicity of chemotherapeutic agents in drug-resistant cells. S07-2010 significantly inhibits the proliferation of drug-resistant cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1223194-71-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150644.
S 07662
S 07662. Group: Biochemicals. Grades: Purified. CAS No. 883226-64-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
S0859
S0859 is a selective, high-affinity generic Na+/HCO3- transporter (NBC) inhibitor. S0859 reversibly inhibits NBC-mediated intracellular pH (pHi) recovery (Ki=1.7 μM, full inhibition at approximately 30 μM). Uses: Scientific research. Category: Signaling pathways. CAS No. 1019331-10-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-15529.
S100P-IN-1 (Compound 4) is a S100P inhibitor with an IC50 of 22.7 nM. S100P-IN-1 shows anti-metastatic effects on pancreatic cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 690991-06-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146695.
S107
S107 is an orally available, blood brain barrier-permeable compound, which stabilizes RyR2 channels by enhancing the binding of calstabin 2 to the mutant Ryr2-R2474S channel. S107 inhibits Ca2+ leakage from the sarcoplasmic reticulum (SR) and prevents cardiac arrhythmias and raises the seizure threshold[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 927871-76-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15292.
S-((1-(2,2-Dimethyl-5-oxo-1,3-dioxolan-4-yl)cyclopropyl)methyl) Ethanethioate is an intermediate in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
S-(1,2-Dicarboxyethyl)glutathione
It shows anti-inflammatory and anti-anaphylactic effects in vivo and inhibits histamine release from rat mast cells in vitro. Synonyms: S-(alpha,beta-Dicarboxyethyl)glutathione; H-Glu(Cys(1,2-dicarboxyethyl)-Gly-OH)-OH. Grade: 95%. CAS No. 1115-52-2. Molecular formula: C14H21N3O10S. Mole weight: 423.40.
S)-(-)-1,2-Propylene carbonate
1g Pack Size. Group: Building Blocks, Chiral Compounds, Organics. Formula: C4H6O3. CAS No. 51260-39-0. Prepack ID 22687224-1g. Molecular Weight 102.09. See USA prepack pricing.
S130
S130 is a high affinity, selective inhibitor of ATG4B (a major cysteine protease) with an IC50 of 3.24 μM. S130 suppresses autophagy flux[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1160852-22-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112818.
S14161
Potent antileukemia and antimyeloma compound. Apoptosis inducer, delays tumor growth. Cyclin D2 promoter transactivation inhibitor. PI3 kinase (PI3K) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 883046-50-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C17H14FNO4. US Biological Life Sciences.
Worldwide
S 14506 hydrochloride
S 14506 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 286369-38-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
S-14506 hydrochloride
S-14506 hydrochloride is a potent 5-HT1A agonist, as well as 5-HT2A/2C antagonist. S-14506 hydrochloride displays dopamine antagonist properties by blocking dopamine D2 receptors. S-14506 hydrochloride inhibits the in vivo binding of [3H]raclopride in striatum and olfactory bulbs. S-14506 hydrochloride has the potential for the research of anxiolytic agent[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 286369-38-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110024.
S14-95
S14-95 is an inhibitor of the JAK/STAT pathway isolated from Penicillium sp. 14-95. It inhibits the IFN-gamma mediated expression of the reporter gene with IC50 values of 2.5 to approximately 5 mg/ml. It inhibits the expression of the proinflammatory enzymes COX-2 and NOS II at 5 microg/ml (10.8 mM) in LPS/IFN-gamma stimulated J774 mouse macrophages. Molecular formula: C28H34O5. Mole weight: 450.57.
S-15183a
S-15183a is a sphingosine kinase inhibitor produced by Zopfiella inermis SANK 15183. It inhibited sphingosine kinase from rat liver with IC50 value of 2.5 μmol/L. It also inhibited endogenous SPH kinase activity in intact platelets. Synonyms: S-15183 a. Molecular formula: C25H36O5. Mole weight: 416.5.
S-15183b
S-15183b is a sphingosine kinase inhibitor produced by Zopfiella inermis SANK 15183. It inhibited sphingosine kinase from rat liver with IC50 value of 2.5 μmol/L. Synonyms: S-15183 b. Molecular formula: C27H40O5. Mole weight: 444.6.
S 17092
S 17092 (S 17092-1) is an orally active cerebral prolyl-endopeptidase (PEP) inhibitor with an IC50 of 1.2 nM. S 17092 inhibits cell apoptosis. S 17092 mechanism of action is to inhibit the activity of PEP, slowing down the degradation of neuroactive peptides and thus enhancing memory function. S 17092 can be used for the research of memory impairment and cognitive disorders associated with cerebral aging[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S 17092-1. CAS No. 176797-26-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15114.
S 18986
S 18986. Group: Biochemicals. Grades: Purified. CAS No. 175340-20-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
S 18986
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors. S 18986 shows cognitive enhancing properties in rodents. S 18986 activates the release of noradrenaline and acetylcholine in rat hippocampus and enhances rat memory in object-recognition tests[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 175340-20-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10936.
S-19159
S-19159 is a modulator of neurite outgrowth produced by the ascomycete Preussia aemulans. Synonyms: S 19159; S19159. Molecular formula: C30H44O5. Mole weight: 484.7.
s-(-)-1-Isopropylamino-3-(2-allylphenoxy)-2-propanol hydrochloride. CAS No. 15132-12-4. Product ID: ACM15132124. Alfa Chemistry - ISO 9001:32057 Certified.
S- (1-Methyl-2-hydroxyethyl) glutathione (Mixture of Diastereomers)
A glutamyl cysteinyl glycine (GSH) derivative. Group: Biochemicals. Alternative Names: L-γ-Glutamyl-S-(1-methyl-2-hydroxyethyl)-L-cysteinylgycine; N-[N-L-γ-glutamyl-S-(1-methyl-2-hydroxyethyl)-L-cysteinyl]glycine. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
S1P4 Receptor Antagonist (CYM50358)
An arylcarboxamide that acts as a potent and selective sphingosine-1-phosphate receptor 4 (S1P4) antagonist (IC50=25nM), among a panel of five S1P receptors. It is shown to inhibit other S1P isoforms only at much higher concentrations (IC50 = 6.4uM, 3.9uM, 5.5uM, and 25uM for S1P1, S1P2, S1P5, and S1P3 (95% inhibition), respectively). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
S1PL-IN-1
S1PL-IN-31 (compound ) is an oral active sphingosine-1-phosphate (S1P) lyase inhibitor with the IC50 of 210 nM. S1PL-IN-31 is Smoothened receptor antagonist with the IC50 of 440 nM. S1PL-IN-31 can be used for study of experimental autoimmune encephalomyelitis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1538574-95-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-115566.
S-1-Propenyl-L-cysteine
S-1-Propenyl-L-cysteine is a stereoisomer of S-allyl-l-cysteine, extracted from garlic, with immunomodulatory effects and reduces blood pressure in a hypertensive animal model[1]. S-1-Propenyl-L-cysteine exhibits antioxidative efficacy through a NO-dependent BACH1 signaling pathway[2]. S-1-Propenyl-L-cysteine is orally active. Uses: Scientific research. Category: Signaling pathways. CAS No. 52438-09-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111827.
S1QEL1.1
S1QEL1.1 is a small molecule inhibitor that specifically inhibits the generation of superoxide and hydrogen peroxide at the IQ site during reverse electron transfer in mitochondrial respiratory chain complex I (Complex I), with an IC50 of 0.07 μM. S1QEL1.1 can significantly reduce the activation of cysteine-aspartic protease (caspase) triggered by endoplasmic reticulum stress. S1QEL1.1 helps to decrease excessive proliferation of stem cells by inhibiting the Reactive Oxygen Species signaling pathway initiated by endoplasmic reticulum stress[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 897613-29-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-129115.
S1RA
S1RA (E-52862) is a highly selective σ1 receptor (σ1R) antagonist with Kis of 17 nM and 23.5 nM for human σ1R and guinea pig σ1R, respectively. S1RA has Moderate antagonistic activity for human 5-HT2B receptor (Ki= 328 nM). S1RA has antinociceptive effects in neuropathic pain models. S1RA prevents mechanical and cold hypersensitivity in Oxaliplatin (HY-17371)-treated mice[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E-52862. CAS No. 878141-96-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-18099.
S1RA hydrochloride
S1RA (E-52862) hydrochloride is an orally active and selective sigma-1 receptor (σ1R) antagonist with a Ki value of 17 nM. S1RA hydrochloride shows good selectivity against σ2R (Ki >1000 nM). S1RA hydrochloride is a human 5-HT2B receptor antagonist with an IC50 value of 4.7 μM. S1RA hydrochloride inhibits neuropathic pain and activity-induced spinal sensitization[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E-52862 hydrochloride. CAS No. 1265917-14-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-18099A.
S-(-)-1-(t-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol maleate salt
S-(-)-1-(t-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol maleate salt. Group: Biochemicals. Alternative Names: Timolol maleate. Grades: Highly Purified. CAS No. 26921-17-5. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C13H24N4O3S·C4H4O4. US Biological Life Sciences.
Worldwide
S-22153
S-22153 is a potent melatonin receptor antagonist with EC50 values of 19 nM, 4.6 nM for hMT1 and hMT2 melatonin receptor, respectively. S-22153 has Ki values of 8.6 nM (CHO cells) and 16.3 nM (HEK cells) for hMT1, and 6.0 nM (CHO cells) and 8.2 nM (HEK cells) for hMT2. S-22153 is a specific ligand of MT1 and MT2 melatonin receptors subtypes[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 180304-07-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114962.
1g Pack Size. Group: Chiral Compounds, Ligands. Formula: C44H32P2. CAS No. 76189-56-5. Prepack ID 28868113-1g. Molecular Weight 622.67. See USA prepack pricing.
S-2,3-Dicarboxyaziridine
It is produced by the strain of Streptomyces sp. It has the activity of resistant gram-positive and negative bacteria, especially the Aeromonas salmonecida. Synonyms: 2,3-Dicarboxyaziridine. CAS No. 57528-68-4. Molecular formula: C4H5NO4. Mole weight: 131.09.
S 24795
S 24795. Group: Biochemicals. Grades: Purified. CAS No. 304679-75-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
s-[2-(4-Azidosalicylamido)ethylthio]-2-thiopyridine. Alternative Names: 4-Azido-2-hydroxy-N-[2-(2-pyridinyldithio)ethyl]benzamide; AET. CAS No. 164575-82-0. Product ID: ACM164575820. Molecular formula: C14H13N5O2S2. Alfa Chemistry - ISO 9001:32057 Certified.
S-(2,4-Dimethylbenzene)-D,L-cysteine.
rac-Cysteine derivative. Group: Biochemicals. Alternative Names: S-(2,4-Dimethylbenzene) rac-Cysteine; S-(2,4-Dimethylbenzene) (R,S)-Cysteine. Grades: Highly Purified. CAS No. 1357350-92-5. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
S-(2,4-Dinitrophenyl)-glutathione
S-(2,4-Dinitrophenyl)-glutathione. Group: Biochemicals. Alternative Names: SDNPG. Grades: Highly Purified. CAS No. 26289-39-4. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H19N5O10S. US Biological Life Sciences.
Worldwide
S-(2,4-Dinitrophenyl)-Glutathione (SDNPG)
A substrate for Glutathione-S-Transferase, with a kinetically determined dissociation constant of 7uM. Group: Biochemicals. Alternative Names: SDNPG. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
S-[2-(4-Pyridyl)ethyl] Thiolactic Acid, Sodium Salt
S-[2-(4-Pyridyl)ethyl] Thiolactic Acid, Sodium Salt. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
S 25585
S 25585. Group: Biochemicals. Grades: Purified. CAS No. 263849-50-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
S-(2,5-Dimethylbenzene)-L-cysteine
L-Cysteine derivative. Group: Biochemicals. Alternative Names: S-(2,5-Dimethylphenyl)-L-cysteine. Grades: Highly Purified. CAS No. 1331895-23-8. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
S26131
S26131 (compound 5) is a potent and selective MT1 melatoninergic ligand, and the Ki values are 0.5 and 112 nM for MT1 and MT2, respectively. S26131 behaves as an MT1 and MT2 antagonist[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 296280-56-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-122136.
S26948
S26948. Group: Biochemicals. Grades: Purified. CAS No. 353280-43-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
S29434
S29434 (NMDPEF) is a potent, competitive, selective and cell-permeable inhibitor of quinone reductase 2 (QR2), with IC50s ranging from 5 to 16 nM for human QR2 at different organizational levels, and has good selectivity for QR2 over QR1. S29434 induces autophagy and inhibits QR2-mediated ROS production[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NMDPEF. CAS No. 874484-20-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122614.
S-2-Acetylthio-3-phenylpropionic Acid
A IMP-1 metallo-b-lactamase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
S-(+)-2-Amino-1-butanol
5g Pack Size. Group: Amino Acids, Chiral Compounds, Research Organics & Inorganics. Formula: C4H11NO. CAS No. 5856-62-2. Prepack ID 15714187-5g. Molecular Weight 89.14. See USA prepack pricing.
1g Pack Size. Group: Organics, Solvents. Formula: C4H10O. CAS No. 4221-99-2. Prepack ID 50323992-1g. Molecular Weight 74.12. See USA prepack pricing.
S-(2-Carboxyethyl)-L-cysteine
An advanced glycation end product, found in elevated concentrations within Diabetes Mellitus patients. Group: Biochemicals. Alternative Names: L-3-[ (2-Carboxyethyl) thio]alanine; 2-Amino-4-thiaheptanedioic Acid; S-(2-Carboxyethyl)cysteine; CEC: Grades: Highly Purified. CAS No. 100429-59-2. Pack Sizes: 100mg. US Biological Life Sciences.
s(+)-2-Hydroxy-4-phenylbutyric acid. Alternative Names: 2-(S)-HYDROXY-4-PHENYL-BUTYRIC ACID;(S)-2-HYDROXY-4-PHENYLBUTYRIC ACID;(S)-2-Hydroxy-4-phenylbutanoic acid;(S)-4-Phenyl-2-hydroxybutyric acid. CAS No. 115016-95-0. Product ID: ACM115016950. Molecular formula: C10H12O3. Mole weight: 180.20. Alfa Chemistry - ISO 9001:32057 Certified.
S-(2-Hydroxy-5-nitrobenzoyl)-6-thioguanosine
S-(2-Hydroxy-5-nitrobenzoyl)-6-thioguanosine. Group: Biochemicals. Alternative Names: 2-Amino-6-[(2-hydroxy-5-nitrobenzyl)thio]-9-(b-D-ribofuranosyl)purine. Grades: Highly Purified. CAS No. 41094-07-9. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C17H18N6O7S. US Biological Life Sciences.
Worldwide
S-(2-Hydroxy-5-nitrobenzoyl)-6-thioinosine
S-(2-Hydroxy-5-nitrobenzoyl)-6-thioinosine. Group: Biochemicals. Alternative Names: 6-[(2-Hydroxy-5-nitrobenzyl)thio]-9-b-D-ribofuranosylpurine. Grades: Highly Purified. CAS No. 56964-73-9. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C17H17N5O7S. US Biological Life Sciences.
Worldwide
S- (2-Hydroxyethyl) glutathione
A glutathione derivative as inhibitor of glutathione S-transferase. Group: Biochemicals. Alternative Names: L-γ-Glutamyl-S-(2-hydroxyethyl)-L-cysteinylglycine; L-N-[1-[ (Carboxymethyl) carbamoyl]-2-[ (2-hydroxyethyl) thio]ethyl]glutamine; N-[N-L-γ-Glutamyl-S-(2-hydroxyethyl)-L-cysteinyl]glycine; S-( β -Hydroxyethyl) glutathione. Grades: Highly Purified. CAS No. 28747-20-8. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
S- (2-Hydroxyethyl) glutathione-d4 Hydrochloride
A labeled glutathione derivative as inhibitor of glutathione S-transferase. Group: Biochemicals. Alternative Names: L-γ-Glutamyl-S-(2-hydroxyethyl-d4)-L-cysteinylglycine Hydrochloride; N-[1-[ (Carboxymethyl) carbamoyl]-2-[ (2-hydroxyethyl-d4) thio]ethyl]tamine Hydrochloride; S-( β-Hydroxyethyl-d4)glutathione Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
S- (2-Hydroxyethyl) glutathione Hydrochloride
A glutathione derivative as inhibitor of glutathione S-transferase. Group: Biochemicals. Alternative Names: L-γ-Glutamyl-S-(2-hydroxyethyl)-L-cysteinylglycine Hydrochloride; N-[1-[ (Carboxymethyl) carbamoyl]-2-[ (2-hydroxyethyl) thio]ethyl]. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.