A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
C004019 is a BBB-penetrable and small-molecule PROTAC that targets tau. C004019 can simultaneously recruit tau and E3 ligase, and effectively clear tau proteins by promoting the ubiquitination and proteasome-dependent degradation of tau, thereby improving synaptic and cognitive functions in Alzheimer's disease (AD) mice. C004019 can be used in the research of AD and tau protein-related diseases. (Pink: Ligand for target protein (HY-138679); Black: linker (HY-140189); Blue: E3 Ligase Ligand (HY-138678))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2417159-57-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138669.
C-021
C-021 is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor with an IC50 of 18 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 864289-85-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103364.
C 021 dihydrochloride
C 021 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 864289-85-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
C-021 dihydrochloride
C-021 dihydrochloride is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 dihydrochloride effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor with an IC50 of 18 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1784252-84-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-103364A.
C-1
C-1. Group: Biochemicals. Grades: Purified. CAS No. 84468-24-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
C10:0 L-carnitine-d9 (HCl salt)
C10:0 L-carnitine-d9 (HCl salt). Alternative Names: Decanoyl L-carnitine-d9 (HCl salt). CAS No. 2847775-92-0. Purity: >99%. Product ID: ALCFA2847775920. Molecular formula: C17H25D9ClNO4. Mole weight: 360.97. Alfa Chemistry - ISO 9001:32057 Certified.
C100 Technical
C100 Technical.
C101 Dye
C101 Dye. Uses: For analytical and research use. CAS No. 1224601-35-7. Mole weight: 950.19. Catalog: AP1224601357.
C101 Dye
C101 Dye is ruthenium (Ru) based organic dye that can be used as a heteroleptic thiophene-based sensitizer. It has a high extinction coefficient of 17500 Lmol-1cm-1 and facilitates the enhancement of optoelectronic properties of electrochemical devices. Alternative Names: cis-Bis(isothiocyanato)(2,2'-bipyridyl-4,4'-dicarboxylato)(4,4'-bis(5-hexylthiophen-2-yl)-2,2'-bipyridyl)ruthenium(II), Ruthenate(2-), [[2,2'-bipyridine]-4,4'-dicarboxylato(2-)-N1,N1'][4,4'-bis(5-hexyl-2-thienyl)-2,2'-bipyridine-N1,N1']bis(thiocyanato-N)-, hydrogen (1:2). CAS No. 1224601-35-7. SMILES: OC(C1=CC(C2=CC(C(O)=O)=CC=N2)=NC=C1)=O.S=C=N[Ru]N=C=S.CCCCCCC(S3)=CC=C3C4=CC=NC(C5=NC=CC(C6=CC=C(CCCCCC)S6)=C5)=C4. InChI: 1S/C30H36N2S2.C12H8N2O4.2CNS.Ru/c1-3-5-7-9-11-25-13-15-29(33-25)23-17-19-31-27(21-23)28-22-24(18-20-32-28)30-16-14-26(34-30)12-10-8-6-4-2;15-11(16)7-1-3-13-9(5-7)10-6-8(12(17)18)2-4-14-10;2*2-1-3;/h13-22H,3-12H2,1-2H3;1-6H,(H,15,16)(H,17,18);;;/q;;2*-1;+2.
C104
C104.
C106 Dye
C106 Dye. Uses: For analytical and research use. CAS No. 1152310-69-4. Catalog: AP1152310694.
C10 bisphosphonate is an inhibitor of acid sphingomyelinase. Alternative Names: 1-aminodecane-1,1-bisphosphonic acid. Grades: >99%. CAS No. 15049-93-1. Molecular formula: C10H25NO6P2. Mole weight: 317.26.
C11 BODIPY 581/591
C11 BODIPY 581/591 is a lipid-soluble ratiometric fluorescent indicator of lipid oxidation. CAS No. 217075-36-0. Molecular formula: C30H35BF2N2O2. Mole weight: 504.43.
C11 TopFluor® GM3 Ammonium salt - a highly pure, fluorescent lipid probe that delves into the intricacies of ganglioside metabolism within biological samples. This remarkable probe is not just limited to that though; it can alight on GM3 gangliosides within cells that are involved in disruptive lipid-related diseases like neurodegeneration, inherited metabolic disorders and cancer. That's not all - TopFluor® GM3's exceptional structural and fluorescence properties place it on a pedestal as an invaluable tool for scrutinizing lipid membrane dynamics and signal transduction pathways with great precision. Alternative Names: C11 TopFluor GM3 Ganglioside (ammonium salt); Borate(1-), [N-[(1S,2R,3E)-1-[[[O-(N-acetyl-α-neuraminosyl)-(2→3)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]-λ-(3,5-dimethyl-2H-pyrrol-2-ylidene-κN)-3,5-dimethyl-1H-pyrrole-2-dodecanamidato(2-)-κN1]difluoro-, ammonium (1:1), (T-4)-; (T-4)-[N-[(1S,2R,3E)-1-[[[O-(N-Acetyl-α-neuraminosyl)-(2→3)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]-λ-(3,5-dimethyl-2H-pyrrol-2-ylidene-κN)-3,5-dimethyl-1H-pyrrole-2-dodecanamidato(2-)-κN1]difluoroborate(1-) ammonium salt. CAS No. 2260795-48-8. Molecular formula: C65H110BF2N5O21. Mole weight: 1346.40.
C12:0 L-carnitine-d9 (HCl salt)
C12:0 L-carnitine-d9 (HCl salt). Alternative Names: Lauroyl L-carnitine-d9 (HCl salt). CAS No. 2245711-25-3. Purity: >99%. Product ID: ALCFA2245711253. Molecular formula: C19H29D9ClNO4. Alfa Chemistry - ISO 9001:32057 Certified.
C12-13mixturealcohol glycidylether
C12-13mixturealcohol glycidylether. CAS No. 120547-52-6. Purity: 96%. Product ID: ACM120547526. Alfa Chemistry - ISO 9001:32057 Certified.
C12-15 alkyl lactate
C12-15 alkyl lactate. CAS No. 93925-36-1.
C12-200
C12-200 is almost a macromolecule. It contains multiple tertiary amines, the pKa of which should also be close to but no greater than 7. Ionizable lipids in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based therapeutics. Alternative Names: 1,1'-((2-(4-(2-((2-(Bis(2-hydroxydodecyl)amino)ethyl)(2-hydroxydodecyl)amino)ethyl)piperazin-1-yl)ethyl)azanediyl)bis(dodecan-2-ol). Grades: >98%. CAS No. 1220890-25-4. Molecular formula: C70H145N5O5. Mole weight: 1136.93.
C12-200
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1220890-25-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145405.
Ceramide is one of the simplest sphingolipids, consisting of a sphingosine base N-linked to a fatty acid, and is a membrane mediator for cell-signaling events. N-Acyl chain length of membrane ceramides can influence bidimensional transitions, condensed domain morphology, and interfacial thickness. Group: Biochemicals. Alternative Names: N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]dodecanamide; N- [ (1S, 2R, 3E) -2-Hydroxy-1- (hydroxymethyl) -3-heptadecenyl] dodecanamide; [R- [R*, S*- (E) ] ] -N- [2-Hydroxy-1- (hydroxymethyl) -3-heptadecenyl] dodecanamide; N-Lauroyl-D-erythro-sphingosine; N-Laurylsphingosine. Grades: Highly Purified. CAS No. 74713-60-3. Pack Sizes: 5mg. US Biological Life Sciences.
C12 ceramide-1,3-cyclic-phosphate (d18:1/12:0). Alternative Names: N-lauroyl-ceramide-1,3-cyclic-phosphate (ammonium salt). CAS No. 2410279-77-3. Purity: >99%. Product ID: ALCFA2410279773. Molecular formula: C30H61N2O5P. Mole weight: 560.8. Alfa Chemistry - ISO 9001:32057 Certified.
C12 Ceramide-1-Phosphate (d18:1/12:0)
C12 Ceramide-1-Phosphate (d18:1/12:0). Alternative Names: N-(dodecanoyl)-sphing-4-enine-1-phosphate CerP(d18:1/12:0). CAS No. 799812-62-7. Purity: >99%. Product ID: ALCFA799812627. Molecular formula: C30H63N2O6P. Mole weight: 578.805. Alfa Chemistry - ISO 9001:32057 Certified.
C12E5
C12E5 acts as a non-ionic surfactant and can be used to extract membrane proteins, such as fusion protein and haemagglutinin neuraminidase of the Sendai virus. Uses: Non-ionic surfactant. Alternative Names: Pentaethylene glycol monododecyl ether; Dodecyl pentaethylene glycolether; n-Dodecylpentaoxyethylene; Laureth-5; Pentaethylene glycol lauryl ether; Pentaoxyethylene monododecyl ether; Polyoxyethylene (5) lauryl ether; PEG-5 Lauryl ether; 3,6,9,12,15-Pentaoxaheptacosan-1-ol. Grades: ≥95%. CAS No. 3055-95-6. Molecular formula: C22H46O6. Mole weight: 406.60.
C12FDG
C12FDG (5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside) is a lipophilic green fluorescent substrate for β-galactosidase detection. C12-FDG is more sensitive than Fluorescein di(β-D-galactopyranoside) (HY-101895) for beta-galactosidase activity determinations in animal cells (Ex/Em = 488/523 nm)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside. CAS No. 138777-25-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126839.
C12-NBD Glucosyl Ceramide
Glucosyl ceramide (GlcCer) is produced by GlcCer synthase from ceramide in the cytosolic membranes of Golgi. Alternative Names: N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-D-glucosyl-β1-1'-sphingosine. Grades: >99%. CAS No. 474943-01-6. Molecular formula: C42H71N5O11. Mole weight: 822.04.
C12-NBD Phytosphingosine
C12-NBD Phytosphingosine is a fluorescent derivative of phytosphingosine. Phytosphingosine is a naturally occurring lipid compound localized in skin, kidney and intestines. Alternative Names: N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-phytosphingosine. Grades: >99%. CAS No. 388566-94-7. Molecular formula: C36H63N5O7. Mole weight: 677.92.
C12 NBD Sphingomyelin
C12 NBD sphingomyelin is an active derivative of Sphingomyelin (HY-113498) that is tagged with fluorescent C12 nitrobenzoxadiazole (C12 NBD). C12 NBD sphingomyelin can be used as a sphingomyelinase substrate for studying the metabolism and transport of sphingomyelins (Ex=470 nm, Em=525 nm)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 254117-01-6. Pack Sizes: 100 μg. Product ID: HY-D1584.
C12-Sphingosine
C12-Sphingosine. Group: Biochemicals. Alternative Names: [R-[R*,S*-(E)]]-2-Amino-4-dodecene-1,3-diol; (2S,3R,4E)-2-Amino-4-dodecene-1,3-diol. Grades: Highly Purified. CAS No. 128427-86-1. Pack Sizes: 10mg. Molecular Formula: C12H25NO2, Molecular Weight: 215.33. US Biological Life Sciences.
C14:0 L-carnitine-d9. Alternative Names: Myristoyl L-carnitine-d9. CAS No. 2245713-18-0. Purity: >99%. Product ID: ALCFA2245713180. Molecular formula: C21H32D9NO4. Mole weight: 380.62. Alfa Chemistry - ISO 9001:32057 Certified.
C14-4
C14-4 is an ionizable lipid utilized for the synthesis of lipid nanoparticles (LNPs). C14-4 enhances mRNA delivery, enabling the effective transport of mRNA to primary human T cells, which in turn induces functional protein expression. C14-4 demonstrates high transfection efficiency while maintaining low cytotoxicity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2639634-80-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-148842.
C14-Ceramide
C14-Ceramide. Group: Biochemicals. Alternative Names: N-Myristoyl-D-sphingosine; N- [ (1S, 2R, 3E) -2-hydroxy-1- (hydroxymethyl) -3-heptadecenyl] tetradecanamide; N-[2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-, [R-[R*,S*-(E)]]tetradecanamide. Grades: Highly Purified. CAS No. 34227-72-0. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C32H63NO3. US Biological Life Sciences.
Worldwide
C14 Ceramide (d18:1/14:0)
C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's and diabetes research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 123408-74-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-124177A.
C14 dihydroceramide
C14 dihydroceramide. Group: Biochemicals. Alternative Names: N-Myristoylsphinganine. Grades: Highly Purified. CAS No. 61389-70-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C32H65NO3. US Biological Life Sciences.
C14orf49 protein (221-232) is a peptide derived from C14orf49 protein. C14orf49 protein is a probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Alternative Names: SYNE3 (221-232).
C14TKL-1
C14TKL-1 is an endogenous human tachykinin-like peptide and a potent NK1 receptor agonist (EC50 = 1 nM). Alternative Names: H-Arg-His-Arg-Thr-Pro-Met-Phe-Tyr-Gly-Leu-Met-NH2; L-arginyl-L-histidyl-L-arginyl-L-threonyl-L-prolyl-L-methionyl-L-phenylalanyl-L-tyrosyl-glycyl-L-leucyl-L-methioninamide; Chromosome 14 tachykinin-like peptide 1; C14TKL1; C14TKL 1. Grades: ≥95%. CAS No. 1423381-12-7. Molecular formula: C63H98N20O13S2. Mole weight: 1407.71.
C14TKL-1
C14TKL-1. Group: Biochemicals. Grades: Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
C14TKL-1 acetate
C14TKL-1 acetate is an endogenous human tachykinin-like peptide and a potent NK1 receptor agonist (EC50 = 1 nM). Alternative Names: H-Arg-His-Arg-Thr-Pro-Met-Phe-Tyr-Gly-Leu-Met-NH2.CH3CO2H; L-arginyl-L-histidyl-L-arginyl-L-threonyl-L-prolyl-L-methionyl-L-phenylalanyl-L-tyrosyl-glycyl-L-leucyl-L-methioninamide acetate; Chromosome 14 tachykinin-like peptide 1 acetate; C14TKL1 acetate; C14TKL 1 acetate. Grades: ≥95%. Molecular formula: C65H102N20O15S2. Mole weight: 1467.75.
C15 Ceramide-1-Phosphate-d7 (d18:1-d7/15:0)
C15 Ceramide-1-Phosphate-d7 (d18:1-d7/15:0). Alternative Names: N-pentadecanoyl-ceramide-1-phosphate-d7 (ammonium salt). CAS No. 2315262-27-0. Purity: >99%. Product ID: ALCFA2315262270. Molecular formula: C33H62D7N2O6P. Mole weight: 627.93. Alfa Chemistry - ISO 9001:32057 Certified.
C16
C16. Group: Biochemicals. Grades: Purified. CAS No. 608512-97-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
C16:0 L-carnitine-d9. Alternative Names: Palmitoyl L-carnitine-d9. CAS No. 2847775-90-8. Purity: >99%. Product ID: ALCFA2847775908. Molecular formula: C23H36D9NO4. Mole weight: 408.67. Alfa Chemistry - ISO 9001:32057 Certified.
C16-18:1 PE
C16-18:1 PE, a crucial phospholipid found in cellular membranes, plays a pivotal role in maintaining membrane integrity and functionality. Extensively researched for its therapeutic prowess in treating neurological pathologies and cardiovascular ailments, this lipid derivative showcases promising prospects in biomedical intervention and disease management. Alternative Names: 1-hexadecyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphoethanolamine; PE(O-16:0/18:1(9Z)). CAS No. 119904-40-4. Molecular formula: C39H78NO7P. Mole weight: 704.01.
C16 ceramide is an endogenous ceramide, generated by ceramide synthase 6 (CerS6), that acts as a lipid second messenger to regulate apoptosis and stress signaling. It has also been found to activate NF-κB and PKCζ3. Uses: A predominant, rather hydrophobic natural ceramide. activates a cytosolic serine / threonine protein phosphatase in t9 cells; induces egf receptor phosphorylation in a-431 cells; stimulates ceramide-activated protein kinase. Alternative Names: C16 Ceramide (d18:1/16:0); N-(hexadecanoyl)-sphing-4-enine; N-Palmitoylsphingosine. Grades: 98%. CAS No. 24696-26-2. Molecular formula: C34H67NO3. Mole weight: 537.90.
C16-Ceramide
C16-Ceramide. Group: Biochemicals. Alternative Names: N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-hexadecanamide; (2S, 3R, 4E) -2-N-Palmitoyl octadecasphinga-4-ene. Grades: Highly Purified. CAS No. 24696-26-2. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C34H67NO3. US Biological Life Sciences.
Worldwide
C16 ceramide-1,3-cyclic-phosphate (d18:1/16:0)
C16 ceramide-1,3-cyclic-phosphate (d18:1/16:0). Alternative Names: N-palmitoyl-ceramide-1,3-cyclic-phosphate (ammonium salt). CAS No. 2410279-79-5. Purity: >99%. Product ID: ALCFA2410279795. Molecular formula: C34H69N2O5P. Mole weight: 616.91. Alfa Chemistry - ISO 9001:32057 Certified.
C16-Ceramide (d18:1/16:0) is a natural small molecule activating p53 through the direct and selective binding[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: C16-Ceramide. CAS No. 24696-26-2. Pack Sizes: 10 mM * 1 mL in Ethanol; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100354.
It is a glycosphingolipid that contains a galactose moiety attached to a ceramide acylated with palmitic acid. Alternative Names: D-galactosyl-α-1,1'-N-palmitoyl-D-erythro-sphingosine; Hexadecanamide, N-[(1S,2R,3E)-1-[(α-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-; α C16 Galactosylceramide (d18:1/16:0); C16 α-D-galactosyl ceramide; N-(hexadecanoyl)-1-α-galactosyl-sphing-4-enine; N-((2S,3R,E)-3-hydroxy-1-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)octadec-4-en-2-yl)palmitamide; N-[(2S,3R,4E)-1-(α-D-Galactopyranosyloxy)-3-hydroxy-4-octadecen-2-yl]hexadecanamide; α-GalCer(d18:1/16:0). Grades: >99%. CAS No. 2260795-77-3. Molecular formula: C40H77NO8. Mole weight: 700.04.