A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
I-138 is an orally active, reversible inhibitor of USP1-UAF1 (IC50: 4.1 nM; Ki: 5.4 nM), structurally related to ML323 (HY-17543). I-138 induces monoubiquitination of FANCD2 and PCNA in cells and eliminates USP1 autocleavage in cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2098211-50-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153365.
I-191
I-191 is a potent antagonist of protease activated receptor 2 (PAR2). Synonyms: 4-[8-Tert-Butyl-6-(4-Fluorophenyl)Imidazo[1,2-B]Pyridazine-2-Carbonyl]-3,3-Dimethylpiperazin-2-One; PAR2 Antagonist I-191; SCHEMBL16598387; GTPL10268; BCP32684. Grade: 98%. CAS No. 1690172-25-8. Molecular formula: C23H26FN5O2. Mole weight: 423.5.
I-191
I-191 is a potent, selective protease-activated receptor 2 (PAR2) antagonist[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1690172-25-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117793.
I194496
I194496 is a potent cystathionine γ-lyase (CSE) inhibitor, with an IC50 of 0.79 mM. I194496 can inhibit the growth of human TNBC cells via the dual targeting PI3K/Akt and Ras/Raf/ERK pathway and suppress the metastasis of human TNBC cells via down-regulating Anxa2/STAT3 and VEGF/FAK/Paxillin signaling pathways[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 445238-07-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-169212.
I-287
I-287 is a orally active selective PAR2 inhibitor that acting as a negative allosteric regulator on Gαq and Gα12/13 activity and their downstream effectors. I-287 reduces Complete Freund's adjuvant (HY-153808)-induced inflammation in mice and can be used for inflammation/immunology research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2014368-93-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148016.
I2906
Under in vitro conditions, I2906 showed excellent antimycobacterial activities and low cytotoxicity. In a murine model infected with M. tuberculosis H37Rv, the reductions on bacterial loads of both lungs and spleen were statistically significant (p < 0.05) between I2906-treated mice and untreated controls after 4 weeks. Further, the colony-forming unit counts in the lungs were dramatically lower (p < 0.05) than that of isoniazid-treated mice by the addition of I2906 after 8 weeks. Moreover, survival rate was increased by I2906 treatment. For multidrug-resistant strain infection, bacterial counts were reduced significantly in the lungs and spleen due to I2906 treatment in comparison with data from untreated controls (p < 0.05). Synonyms: I 2906; I-2906. Grade:>98%. CAS No. 331963-29-2. Molecular formula: C25H37N3O4. Mole weight: 443.58.
I2959
I2959 is widely used as a photoinitiator for photochemical cross-linking of hydrogels, and the combination of I2959 and CMA hydrogel has been used as a bio-ink for biological 3D printing applications. In addition, I2959 has a high free radical generation efficiency and is cytotoxic to rapidly dividing cell lines[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 106797-53-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W013508.
I-37 hydrochloride
I-37 hydrochloride is an SOS1 inhibitor. Synonyms: Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-6-(1-methylcyclopropyl)-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-, hydrochloride (1:1); (R)-2-methyl-4-((1-(2-methyl-3-(trifluoromethyl)phenyl)ethyl)amino)-6-(1-methylcyclopropyl)pyrido[4,3-d]pyrimidin-7(6H)-one hydrochloride; US10829487, Example I-37 hydrochloride; I-37 hydrochloride; 2-Methyl-6-(1-methylcyclopropyl)-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]pyrido[4,3-d]pyrimidin-7(6H)-one hydrochloride; I-37 free base. Grade: ≥95%. CAS No. 2929868-91-5. Molecular formula: C22H24ClF3N4O. Mole weight: 452.90.
i3-Bromo-4-nitropyridine
i3-Bromo-4-nitropyridine. Group: Biochemicals. Grades: Highly Purified. CAS No. 89364-04-5. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C5H3BrN2O2. US Biological Life Sciences.
Worldwide
I3IN-002
I3IN-002 is a small-molecule RNA-binding protein IGF2BP3 inhibitor with an IC50 value of approximately 2 μM in SEM cells. I3IN-002 interferes with interaction with m6 A-modified mRNAs, disrupting the stabilization of target genes (such as CDK6, MYC, and BCL2) to inhibit leukemic cell growth, induce cell cycle arrest, and promote apoptosis. I3IN-002 is promising for research of B-cell acute lymphoblastic leukemia[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 552829-57-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-174228.
I3MT-3
I3MT-3 is a potent, selective, and cell-membrane permeable inhibitor of 3-mercaptopyruvate sulfurtransferase (3MST) with IC50 of 2.7 μM. I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes. Synonyms: HMPSNE; 6-Methyl-2-((2-(naphthalen-1-yl)-2-oxoethyl)thio)pyrimidin-4(3H)-one. CAS No. 459420-09-8. Molecular formula: C17H14N2O2S. Mole weight: 310.37.
I3MT-3
I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC50=2.7 μM). I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes.?I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HMPSNE. CAS No. 459420-09-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128206.
I942
I942 is a first in class, selective non-cyclic nucleotide (NCN) EPAC1 agonist. I942 can attenuate proinflammatory cytokine signalling normally associated with cardiovascular diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 868145-09-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-129738.
IA-Alkyne
IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) is a TRP channel (TRPC) agonist and has the potential for the study of respiratory infection[1]. IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling[2]. IA-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide. CAS No. 930800-38-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-136205.
IAANS
IAANS, is a novel sulfhydryl-reactive probe that cna be used as a Fluorescence dye. Group: Biochemicals. Grades: Highly Purified. CAS No. 143756-46-1. Pack Sizes: 10mg, 25mg. Molecular Formula: C18H14IN2NaO4S, Molecular Weight: 504.27. US Biological Life Sciences.
IACS-010759 is an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 inhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS. IACS-010759 has the potential for relapsed/refractory AML and solid tumors research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IACS-10759. CAS No. 1570496-34-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112037.
IACS-010759
IACS-010759 is an orally bioavailable inhibitor of mitochondrial oxidative phosphorylation (OXPHOS), targeting complex I of the electron transport chain (NADH ubiquinone oxidoreductase). Study showed that IACS-010759 induced AMPK activation leading to mTOR suppression which resulted in cell growth inhibition in AML cells. Synonyms: 5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole. Grade: ≥98%. CAS No. 1570496-34-2. Molecular formula: C25H25F3N6O4S. Mole weight: 562.57.
IACS-010759 hydrochloride
IACS-010759 hydrochloride is a potent inhibitor of complex I of OXPHOS. IACS-010759 hydrochloride inhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS. IACS-010759 hydrochloride has the potential for relapsed/refractory AML and solid tumors research. Synonyms: IACS-010759 HCl; IACS-10759 hydrochloride. Grade: 99%. CAS No. 1807523-99-4. Molecular formula: C25H26ClF3N6O4S. Mole weight: 599.03.
IACS-010759 hydrochloride
IACS-010759 hydrochlorideis an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 hydrochlorideinhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS. IACS-010759 hydrochloride has the potential for relapsed/refractory AML and solid tumors research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IACS-10759 hydrochloride. CAS No. 1807523-99-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112037A.
IACS-010759 (IACS-10759)
IACS-010759 (IACS-10759) is a potent and selective oxidative phosphorylation inhibitor (IC50 < 10 nM) that blocks cellular respiration through inhibition of complex I. Group: Inhibitors. CAS No. 1570496-34-2. Pack Sizes: 5mg. Product ID: S8731. Formula: C25H25F3N6O4S. Smiles: CC1=NC(=NN1CC2=CC(=CC=C2)N3CCC(CC3)S(=O)(=O)C)C4=NC(=NO4)C5=CC=C(C=C5)OC(F)(F)F. Storage Conditions: 3 years -20°C powder.
United States; Europe
IACS-13909
IACS-13909 is a specific and potent allosteric inhibitor of SHP2 that suppresses signaling through the MAPK pathway. IACS-13909 potently impeded proliferation of tumors harboring a broad spectrum of activated RTKs as the oncogenic driver. Synonyms: BBP-398. CAS No. 2160546-07-4. Molecular formula: C17H18Cl2N6. Mole weight: 377.27.
IACS-52825
IACS-52825 is a potent and selective DLK inhibitor with Kd of 1.3 nM, useful for the study of chemotherapy-induced peripheral neuropathy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2640376-72-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-155089.
IACS-8779
IACS-8779 is a highly potent agonist of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. IACS-8779 shows robust activation of the STING pathway in vitro and a superior systemic anti-tumor response in the B16 murine model of melanoma when compared to one of the clinical benchmark compounds. Synonyms: SCHEMBL23046679; 2243079-26-5; AKOS040733407. Grade: >98%. CAS No. 2243079-26-5. Molecular formula: C21H25N9O10P2S2. Mole weight: 689.56.
IACS-8803
IACS-8803 is a highly potent stimulator of interferon genes (STING) agonist with robust systemic antitumor efficacy. Compared to one of the clinical benchmark compounds, it shows robust activation of the STING pathway in vitro and a superior systemic anti-tumor response in the B16 murine model of melanoma. Synonyms: CHEMBL4596454; SCHEMBL22930678; SCHEMBL23710564; 2095690-70-1; AKOS040733408. Grade: >98%. CAS No. 2095690-70-1. Molecular formula: C20H23FN10O9P2S2. Mole weight: 692.53.
IACS-8803 diammonium
IACS-8803 diammonium is a highly potent cyclic dinucleotide, which shows robust activation of the STING pathway in vitro and a superior systemic anti-tumor response in the B16 murine model of melanoma when compared to one of the clinical benchmark compounds. Synonyms: IACS-8803 (diammonium). Grade: 98%. Molecular formula: C20H29FN12O9P2S2. Mole weight: 726.60.
IACS-8803 disodium
IACS-8803 disodium is one of the STING agonists. Synonyms: IACS-8803 (disodium). Grade: 98%. CAS No. 2243079-36-7. Molecular formula: C20H23FN10Na2O9P2S2. Mole weight: 738.51.
IACS-8803 disodium
IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 disodium has a robust systemic antitumor efficacy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2243079-36-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-130115A.
IACS-9571
IACS-9571, a benzoimidazol derivative, has been found to be a TRIM24 and BRPF1 inhibitor and could be probably significant in anticancer studies. Synonyms: N-(6-(3-(4-(dimethylamino)butoxy)-5-propoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-3,4-dimethoxybenzenesulfonamide; IACS-9571; IACS 9571; IACS9571; IACS 009571-001-4. Grade: 98%. CAS No. 1800477-30-8. Molecular formula: C32H42N4O8S. Mole weight: 642.77.
IACS-9571 hydrochloride
IACS-9571 hydrochloride is a potent and selective TRIM24 and BRPF1 inhibitor, with an IC50 of 8 nM for TRIM24, and Kds of 31 nM and 14 nM for TRIM24 and BRPF1, respectively. Synonyms: ASIS-P040 hydrochloride; N-(6-{3-[4-(Dimethylamino)butoxy]-5-propoxyphenoxy}-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-3,4-dimethoxybenzenesulfonamide hydrochloride (1:1); Benzenesulfonamide, N-[6-[3-[4-(dimethylamino)butoxy]-5-propoxyphenoxy]-2,3-dihydro-1,3-dimethyl-2-oxo-1H-benzimidazol-5-yl]-3,4-dimethoxy-, hydrochloride (1:1). Grade: ≥95%. CAS No. 2319611-93-1. Molecular formula: C32H43ClN4O8S. Mole weight: 679.22.
IACS-9571 hydrochloride
IACS-9571 (ASIS-P040) hydrochloride is a potent and selective inhibitor of TRIM24 and BRPF1, with an IC50 of 8 nM for TRIM24, and Kds of 31 nM and 14 nM for TRIM24 and BRPF1, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASIS-P040 hydrochloride. CAS No. 2319611-93-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-102000B.
Iacvita-[d10]
Iacvita-[d10] is an isotope labelled compound of Bis-(tetramethyl hydroxypiperidinyl) sebacate, which is used as a radiolabelled internal standard. Synonyms: Bis-(tetramethyl hydroxypiperidinyl) sebacate-d10; Decandioic acid, bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl) ester-d10; bis(1-hydroxy-2,2,6,6-tetramethylpiperidin-4-yl) decanedioate-d10. Grade: > 95%. Molecular formula: C28H42D10N2O6. Mole weight: 522.78.
Iadademstat
Iadademstat (ORY-1001) is a highly potent, orally active and selective LSD1 (KDM1A) inhibitor with antileukemic activity. Iadademstat can be used for relapsed or refractory acute myeloid leukemia research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ORY-1001. CAS No. 1431304-21-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-109117.
Iadademstat dihydrochloride
Iadademstat (ORY-1001) dihydrochloride is a selective irreversible lysine (K)-specific demethylase 1A (KDM1A/LSD1) inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ORY-1001 dihydrochloride; RG6016 dihydrochloride; RO 7051790 dihydrochloride. CAS No. 1431303-72-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12782T.
Iadademstat dihydrochloride
Iadademstat dihydrochloride is a selective and irreversible inhibitor of lysine (K)-specific demethylase 1A (KDM1A/LSD1). Synonyms: ORY-1001 dihydrochloride; RG6016 dihydrochloride; RO 7051790 dihydrochloride; trans-N1-((1R,2S)-2-Phenylcyclopropyl)cyclohexane-1,4-diamine dihydrochloride; trans-N-[(1R,2S)-2-Phenylcyclopropyl]-1,4-cyclohexanediamine dihydrochloride; 1,4-Cyclohexanediamine, N1-[(1R,2S)-2-phenylcyclopropyl]-, trans-, hydrochloride (1:2). Grade: ≥98%. CAS No. 1431303-72-8. Molecular formula: C15H24Cl2N2. Mole weight: 303.27.
Iadademstat (ORY-1001) Dihydrochloride
ORY-1001 (RG-6016) 2HCl is an orally active and selective lysine-specific demethylase LSD1/KDM1A inhibitor with IC50 of <20 nM, with high selectivity against related FAD dependent aminoxidases. Phase 1. Group: Inhibitors. Alternative Names: RG-6016. CAS No. 1431326-61-2. Pack Sizes: 5mg. Product ID: S7795. Formula: C15H22N2 . 2HCl. Smiles: C1CC(CCC1N)NC2CC2C3=CC=CC=C3.Cl.Cl. Storage Conditions: 2 years -80 in solvent.
IAG933 (YAP-TEAD-IN-3) is an orally available YAP/TAZ-TEAD inhibitor that has anti-tumor effects and promotes apoptosis. IAG933 YAP-TEAD-IN-3 inhibits Avi-human TEAD4217-434, with an IC50 value of 9 nM[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: YAP-TEAD-IN-3. CAS No. 2714434-21-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-153811.
IAG933
IAG933 (YAP-TEAD-IN-3) is a small molecule and acts as a YAP/TAZ-TEAD inhibitor. It also inhibits NCI-H2052 and can be used in research of tumor invasion and metastatic spread of solid tumors. Group: Inhibitors. Alternative Names: YAP-TEAD-IN-3. CAS No. 2714434-21-4. Pack Sizes: 1mg. Product ID: E1490. Formula: C27H26ClF2N3O4.
United States; Europe
Iα52
Iα52 is a naturally processed peptide containing 52-68 residues of the mouse I-Eα chain that may contribute to the selection of immature T cells. Synonyms: L-Alanine, L-alanyl-L-seryl-L-phenylalanyl-L-α-glutamyl-L-alanyl-L-glutaminylglycyl-L-alanyl-L-leucyl-L-alanyl-L-asparaginyl-L-isoleucyl-L-alanyl-L-valyl-L-α-aspartyl-L-lysyl-; L-Alanyl-L-seryl-L-phenylalanyl-L-α-glutamyl-L-alanyl-L-glutaminylglycyl-L-alanyl-L-leucyl-L-alanyl-L-asparaginyl-L-isoleucyl-L-alanyl-L-valyl-L-α-aspartyl-L-lysyl-L-alanine; Ala-Ser-Phe-Glu-Ala-Gln-Gly-Ala-Leu-Ala-Asn-Ile-Ala-Val-Asp-Lys-Ala. Grade: ≥95%. CAS No. 137756-45-7. Molecular formula: C73H118N20O25. Mole weight: 1675.84.
Iα52 acetate
Iα52 acetate is a naturally processed peptide containing 52-68 residues of the mouse I-Eα chain that may contribute to the selection of immature T cells. Synonyms: Ala-Ser-Phe-Glu-Ala-Gln-Gly-Ala-Leu-Ala-Asn-Ile-Ala-Val-Asp-Lys-Ala-OH.CH3CO2H. Grade: ≥95%. Molecular formula: C75H122N20O27. Mole weight: 1735.89.
IAMA-6
IAMA-6 is a selective NKCC1 inhibitor with neuroprotective effects. IAMA-6 can be used for the study of brain conditions, including drug-resistant epilepsy (e.g. temporal lobe epilepsy (TLE) and Dravet syndrome (DrS)), autism spectrum disorders (ASD) and Down syndrome (DoS)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2497525-96-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-172318.
Ianalumab
Ianalumab (VAY-736) is a human, decarboxylated antibody against BAFF-R. Ianalumab can block the interaction between BAFF and BAFF-R and antagonize the apoptosis protection mediated by BAFF. Ianalumab exerts antibody-dependent cytotoxic (ADCC), depending on effector cell activation mediated by immune receptor tyrosine activation motif (ITAM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VAY-736. CAS No. 1929549-92-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99653.
IAXO-102
IAXO-102 is a TLR4 antagonist that modulates non-hematopoietic TLR4 proinflammatory signalling and inhibits experimental abdominal aortic aneurysm (AAA) development. Synonyms: IAXO-102; 1115270-63-7; CID 25222900; (2R,3R,4S,5R,6S)-2-(aminomethyl)-6-methoxy-4,5-di(tetradecoxy)oxan-3-ol; CHEMBL493017; SCHEMBL20239315; EX-A3691; AKOS037648519; BS-14387; HY-125171; CS-0089755; D70080; Methyl 6-amino-6-deoxy-2,3-di-O-tetradecyl-|A-D-glucopyranoside. CAS No. 1115270-63-7. Molecular formula: C35H71NO5. Mole weight: 585.94.
IAXO-102
IAXO-102 is a TLR4 antagonist which negatively regulates TLR4 signalling. IAXO-102 inhibits MAPK and p65 NF-κB phosphorylation and expression of TLR4 dependent proinflammatory protein. IAXO-102 also prevents experimental abdominal aortic aneurysm development[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1115270-63-7. Pack Sizes: 10 mM * 1 mL in Ethanol; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125171.
IB-00208
IB-00208, a new cytotoxic polycyclic xanthone produced by Actinomadura sp. It also has anti-Gram-positive bacteria activity (MIC=0.09-1.4 nmol/L). Molecular formula: C36H34O12. Mole weight: 658.65.
Ibadronic Acid-d3
Ibadronic Acid-d3. Alternative Names: [1-Hydroxy-3-(methyl-d3-pentylamino)propylidene]bisphosphnic Acid; P,P'-[1-Hydroxy-3-(methyl-d3-pentylamino)propylidene]bisphosphonic Acid; Ibandronate-d3. CAS No. 1130899-41-0. Product ID: ACM1130899410. Molecular formula: C9H20D3NO7P2. Mole weight: 322.25. Alfa Chemistry - ISO 9001:32057 Certified.
Ibalizumab
Ibalizumab (TMB-355) is a humanized anti-CD4 IgG4 monoclonal antibody. Ibalizumab prevents HIV cell entry by binding to CD4 receptor. Ibalizumab can be used for the research of infection, such as HIV-1 infection[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TMB-355; TNX-355. CAS No. 680188-33-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99028.
Ibalizumab
Ibalizumab is a humanized anti-CD4 monoclonal antibody approved for the treatment of HIV-1 infection. Ibalizumab blocks HIV-1 entry into CD4 cells while preserving normal immune function. Synonyms: TMB-355; TNX-355. CAS No. 680188-33-4. Molecular formula: C14H9I3O4. Mole weight: 621.93.
Ib-AMP1
Ib-AMP1 is an antibacterial peptide isolated from Impatiens balsamina. It has activity against gram-positive bacteria and fungi. Synonyms: IBAMP1; Basic peptide AMP1; Gln-Trp-Gly-Arg-Arg-Cys-Cys-Gly-Trp-Gly-Pro-Gly-Arg-Arg-Tyr-Cys-Val-Arg-Trp-Cys.
Ib-AMP2
Ib-AMP2 is an antibacterial peptide isolated from Impatiens balsamina. It has activity against bacteria and fungi. Synonyms: IBAMP2; Basic peptide AMP2; Gln-Tyr-Gly-Arg-Arg-Cys-Cys-Asn-Trp-Gly-Pro-Gly-Arg-Arg-Tyr-Cys-Lys-Arg-Trp-Cys.
Ib-AMP3
Ib-AMP3 is an antibacterial peptide isolated from Impatiens balsamina. It has activity against bacteria and fungi. Synonyms: IBAMP3; Basic peptide AMP3; Gln-Tyr-Arg-His-Arg-Cys-Cys-Ala-Trp-Gly-Pro-Gly-Arg-Lys-Tyr-Cys-Lys-Arg-Trp-Cys.
Ib-AMP4
Ib-AMP4 is an antibacterial peptide isolated from Impatiens balsamina. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: IBAMP4; Basic peptide AMP4; Gln-Trp-Gly-Arg-Arg-Cys-Cys-Gly-Trp-Gly-Pro-Gly-Arg-Arg-Tyr-Cys-Arg-Arg-Trp-Cys.
Ibandronate-[13C,d3] sodium
Ibandronate-[13C,d3] sodium is the labelled analogue of Ibandronate sodium. Ibandronate sodium is a potent bisphosphonate drug and it can be used in the treatment of osteoporosis and metastasis-associated skeletal fractures in people with cancer. Synonyms: Ibandronate 13C D3 sodium. Grade: 95% by HPLC; 98% atom 13C; 98% atom D. CAS No. 1261395-45-2. Molecular formula: C8[13C]H19D3NNaO7P2. Mole weight: 345.22.
Ibandronate Impurity 10
Ibandronate Impurity 10. Uses: For analytical and research use. CAS No. 905808-25-5. Molecular formula: C8H21NO7P2. Mole weight: 305.2. Catalog: APB905808255.
Ibandronate Impurity 11
Ibandronate Impurity 11. Uses: For analytical and research use. Molecular formula: C9H23NO8P2. Mole weight: 335.23. Catalog: APB11733.
Ibandronate Impurity 12
Ibandronate Impurity 12. Uses: For analytical and research use. Molecular formula: C11H17NO8P2. Mole weight: 353.2. Catalog: APB11734.
Ibandronate Impurity 13
Ibandronate Impurity 13. Uses: For analytical and research use. CAS No. 40870-84-6. Molecular formula: C9H19NO2. Mole weight: 173.26. Catalog: APB40870846.
Ibandronate Impurity 2
Ibandronate Impurity 2. Uses: For analytical and research use. CAS No. 2377035-78-2. Molecular formula: C8H18ClNO2. Mole weight: 195.69. Catalog: APB2377035782.
Ibandronate Impurity 5
Ibandronate Impurity 5. Uses: For analytical and research use. CAS No. 26153-88-8. Molecular formula: C7H17N. Mole weight: 115.22. Catalog: APB26153888.
Ibandronate Impurity 6
Ibandronate Impurity 6. Uses: For analytical and research use. Molecular formula: C11H22ClNO4. Mole weight: 267.75. Catalog: APB11732.
Ibandronate Impurity 7
Ibandronate Impurity 7. Uses: For analytical and research use. Molecular formula: C13H25NO4. Mole weight: 259.35. Catalog: APB11731.
Ibandronate Impurity 9
Ibandronate Impurity 9. Uses: For analytical and research use. CAS No. 1859096-06-2. Molecular formula: C1613C5H27N7O14P2. Mole weight: 668.39. Catalog: APB1859096062.
Ibandronate Impurity A
Ibandronate Impurity A. Grade: > 95%. CAS No. 905808-25-5. Molecular formula: C8H21NO7P2. Mole weight: 305.21.
Ibandronate Related Compound A
Ibandronate Related Compound A. Uses: For analytical and research use. CAS No. 625120-81-2. Mole weight: 209.71. Catalog: AP625120812.
Ibandronate sodium
Ibandronate sodium. Group: Biochemicals. Grades: Highly Purified. CAS No. 138844-81-2. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C9H22NNaO7P2. US Biological Life Sciences.
Worldwide
Ibandronate Sodium
Ibandronate sodium is a potent bisphosphonate drug developed by Hoffman La Roche and used in the prevention and treatment of osteoporosis and metastasis-associated skeletal fractures in people with cancer. It may also be used to treat hypercalcemia (elevated blood calcium levels). Ibandronate is indicated for the treatment and prevention of osteoporosis in post-menopausal women. In May 2003, the U.S. Food and Drug Administration (FDA) approved Ibandronate as a daily treatment for post-menopausal osteoporosis. Ibandronate is efficacious for the prevention of metastasis-related bone fractures in multiple myeloma, breast cancer, and certain other cancers. Uses: Bone density conservation agents. Synonyms: Boniva Sodium; Bondronat Sodium; Bonviva Sodium. Grade: >98%. CAS No. 138844-81-2. Molecular formula: C9H22NNaO7P2. Mole weight: 341.21.
Ibandronate sodium impurity 1
Ibandronate sodium impurity 1. Uses: For analytical and research use. Molecular formula: C11H29NO14P4. Mole weight: 523.24. Catalog: APB11729.
Ibandronate sodium impurity 3
Ibandronate sodium impurity 3. Uses: For analytical and research use. CAS No. 953805-81-7. Molecular formula: C8H20NNaO7P2. Mole weight: 327.19. Catalog: APB953805817.
Ibandronate sodium impurity 4
Ibandronate sodium impurity 4. Uses: For analytical and research use. Molecular formula: C4H12NNaO7P2. Mole weight: 271.08. Catalog: APB11730.