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| Product | Description | |
|---|---|---|
| I-138 | I-138 is an orally active, reversible inhibitor of USP1-UAF1 (IC50: 4.1 nM; Ki: 5.4 nM), structurally related to ML323 (HY-17543). I-138 induces monoubiquitination of FANCD2 and PCNA in cells and eliminates USP1 autocleavage in cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2098211-50-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153365. |  |
| I-191 | I-191 is a potent, selective protease-activated receptor 2 (PAR2) antagonist[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1690172-25-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117793. | |
| I194496 | I194496 is a potent cystathionine γ-lyase (CSE) inhibitor, with an IC50 of 0.79 mM. I194496 can inhibit the growth of human TNBC cells via the dual targeting PI3K/Akt and Ras/Raf/ERK pathway and suppress the metastasis of human TNBC cells via down-regulating Anxa2/STAT3 and VEGF/FAK/Paxillin signaling pathways[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 445238-07-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-169212. | |
| I-287 | I-287 is a orally active selective PAR2 inhibitor that acting as a negative allosteric regulator on Gαq and Gα12/13 activity and their downstream effectors. I-287 reduces Complete Freund's adjuvant (HY-153808)-induced inflammation in mice and can be used for inflammation/immunology research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2014368-93-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148016. | |
| I2959 | I2959 is widely used as a photoinitiator for photochemical cross-linking of hydrogels, and the combination of I2959 and CMA hydrogel has been used as a bio-ink for biological 3D printing applications. In addition, I2959 has a high free radical generation efficiency and is cytotoxic to rapidly dividing cell lines[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 106797-53-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W013508. | |
| i3-Bromo-4-nitropyridine | i3-Bromo-4-nitropyridine. Group: Biochemicals. Grades: Highly Purified. CAS No. 89364-04-5. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C5H3BrN2O2. US Biological Life Sciences. |  Worldwide |
| I3IN-002 | I3IN-002 is a small-molecule RNA-binding protein IGF2BP3 inhibitor with an IC50 value of approximately 2 μM in SEM cells. I3IN-002 interferes with interaction with m6 A-modified mRNAs, disrupting the stabilization of target genes (such as CDK6, MYC, and BCL2) to inhibit leukemic cell growth, induce cell cycle arrest, and promote apoptosis. I3IN-002 is promising for research of B-cell acute lymphoblastic leukemia[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 552829-57-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-174228. | |
| I3MT-3 | I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC50=2.7 μM). I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes.?I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HMPSNE. CAS No. 459420-09-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128206. | |
| I942 | I942 is a first in class, selective non-cyclic nucleotide (NCN) EPAC1 agonist. I942 can attenuate proinflammatory cytokine signalling normally associated with cardiovascular diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 868145-09-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-129738. | |
| IA-Alkyne | IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) is a TRP channel (TRPC) agonist and has the potential for the study of respiratory infection[1]. IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling[2]. IA-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide. CAS No. 930800-38-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-136205. | |
| IAANS | IAANS, is a novel sulfhydryl-reactive probe that cna be used as a Fluorescence dye. Group: Biochemicals. Grades: Highly Purified. CAS No. 143756-46-1. Pack Sizes: 10mg, 25mg. Molecular Formula: C18H14IN2NaO4S, Molecular Weight: 504.27. US Biological Life Sciences. | Worldwide |
| IACS-010759 | IACS-010759 is an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 inhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS. IACS-010759 has the potential for relapsed/refractory AML and solid tumors research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IACS-10759. CAS No. 1570496-34-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112037. | |
| IACS-010759 | IACS-010759 is an orally bioavailable inhibitor of mitochondrial oxidative phosphorylation (OXPHOS), targeting complex I of the electron transport chain (NADH ubiquinone oxidoreductase). Study showed that IACS-010759 induced AMPK activation leading to mTOR suppression which resulted in cell growth inhibition in AML cells. Alternative Names: 5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole. Grades: ≥98%. CAS No. 1570496-34-2. Molecular formula: C25H25F3N6O4S. Mole weight: 562.57. |  |
| IACS-010759 | IACS-010759 Inhibitor. Uses: Scientific use. Product Category: T5337. CAS No. 1570496-34-2. |  |
| IACS-010759 hydrochloride | IACS-010759 hydrochlorideis an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 hydrochlorideinhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS. IACS-010759 hydrochloride has the potential for relapsed/refractory AML and solid tumors research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IACS-10759 hydrochloride. CAS No. 1807523-99-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112037A. | |
| IACS-010759 (IACS-10759) | IACS-010759 (IACS-10759) is a potent and selective oxidative phosphorylation inhibitor (IC50 < 10 nM) that blocks cellular respiration through inhibition of complex I. Group: Inhibitors. CAS No. 1570496-34-2. Pack Sizes: 5mg. Product ID: S8731. Formula: C25H25F3N6O4S. Smiles: CC1=NC(=NN1CC2=CC(=CC=C2)N3CCC(CC3)S(=O)(=O)C)C4=NC(=NO4)C5=CC=C(C=C5)OC(F)(F)F. Storage Conditions: 3 years -20°C powder. |  United States; Europe |
| IACS-52825 | IACS-52825 is a potent and selective DLK inhibitor with Kd of 1.3 nM, useful for the study of chemotherapy-induced peripheral neuropathy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2640376-72-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-155089. | |
| IACS-8803 | IACS-8803 is a highly potent stimulator of interferon genes (STING) agonist with robust systemic antitumor efficacy. Compared to one of the clinical benchmark compounds, it shows robust activation of the STING pathway in vitro and a superior systemic anti-tumor response in the B16 murine model of melanoma. Alternative Names: CHEMBL4596454; SCHEMBL22930678; SCHEMBL23710564; 2095690-70-1; AKOS040733408. Grades: >98%. CAS No. 2095690-70-1. Molecular formula: C20H23FN10O9P2S2. Mole weight: 692.53. | |
| IACS-8803 disodium | IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 disodium has a robust systemic antitumor efficacy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2243079-36-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-130115A. | |
| IACS-9571 hydrochloride | IACS-9571 (ASIS-P040) hydrochloride is a potent and selective inhibitor of TRIM24 and BRPF1, with an IC50 of 8 nM for TRIM24, and Kds of 31 nM and 14 nM for TRIM24 and BRPF1, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASIS-P040 hydrochloride. CAS No. 2319611-93-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-102000B. | |
| Iadademstat | Iadademstat (ORY-1001) is a highly potent, orally active and selective LSD1 (KDM1A) inhibitor with antileukemic activity. Iadademstat can be used for relapsed or refractory acute myeloid leukemia research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ORY-1001. CAS No. 1431304-21-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-109117. | |
| Iadademstat dihydrochloride | Iadademstat (ORY-1001) dihydrochloride is a selective irreversible lysine (K)-specific demethylase 1A (KDM1A/LSD1) inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ORY-1001 dihydrochloride; RG6016 dihydrochloride; RO 7051790 dihydrochloride. CAS No. 1431303-72-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12782T. | |
| Iadademstat (ORY-1001) Dihydrochloride | ORY-1001 (RG-6016) 2HCl is an orally active and selective lysine-specific demethylase LSD1/KDM1A inhibitor with IC50 of <20 nM, with high selectivity against related FAD dependent aminoxidases. Phase 1. Group: Inhibitors. Alternative Names: RG-6016. CAS No. 1431326-61-2. Pack Sizes: 5mg. Product ID: S7795. Formula: C15H22N2 . 2HCl. Smiles: C1CC(CCC1N)NC2CC2C3=CC=CC=C3.Cl.Cl. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| IAEAN1-AMMONIUM SULFATE | IAEAN1-AMMONIUM SULFATE. Product ID: ACMA00005054. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| IAG933 | IAG933 (YAP-TEAD-IN-3) is an orally available YAP/TAZ-TEAD inhibitor that has anti-tumor effects and promotes apoptosis. IAG933 YAP-TEAD-IN-3 inhibits Avi-human TEAD4217-434, with an IC50 value of 9 nM[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: YAP-TEAD-IN-3. CAS No. 2714434-21-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-153811. | |
| IAG933 | IAG933 (YAP-TEAD-IN-3) is a small molecule and acts as a YAP/TAZ-TEAD inhibitor. It also inhibits NCI-H2052 and can be used in research of tumor invasion and metastatic spread of solid tumors. Group: Inhibitors. Alternative Names: YAP-TEAD-IN-3. CAS No. 2714434-21-4. Pack Sizes: 1mg. Product ID: E1490. Formula: C27H26ClF2N3O4. | United States; Europe |
| Iα52 | Iα52 is a naturally processed peptide containing 52-68 residues of the mouse I-Eα chain that may contribute to the selection of immature T cells. Alternative Names: L-Alanine, L-alanyl-L-seryl-L-phenylalanyl-L-α-glutamyl-L-alanyl-L-glutaminylglycyl-L-alanyl-L-leucyl-L-alanyl-L-asparaginyl-L-isoleucyl-L-alanyl-L-valyl-L-α-aspartyl-L-lysyl-; L-Alanyl-L-seryl-L-phenylalanyl-L-α-glutamyl-L-alanyl-L-glutaminylglycyl-L-alanyl-L-leucyl-L-alanyl-L-asparaginyl-L-isoleucyl-L-alanyl-L-valyl-L-α-aspartyl-L-lysyl-L-alanine; Ala-Ser-Phe-Glu-Ala-Gln-Gly-Ala-Leu-Ala-Asn-Ile-Ala-Val-Asp-Lys-Ala. Grades: ≥95%. CAS No. 137756-45-7. Molecular formula: C73H118N20O25. Mole weight: 1675.84. | |
| Iα52 acetate | Iα52 acetate is a naturally processed peptide containing 52-68 residues of the mouse I-Eα chain that may contribute to the selection of immature T cells. Alternative Names: Ala-Ser-Phe-Glu-Ala-Gln-Gly-Ala-Leu-Ala-Asn-Ile-Ala-Val-Asp-Lys-Ala-OH.CH3CO2H. Grades: ≥95%. Molecular formula: C75H122N20O27. Mole weight: 1735.89. | |
| IAMA-6 | IAMA-6 is a selective NKCC1 inhibitor with neuroprotective effects. IAMA-6 can be used for the study of brain conditions, including drug-resistant epilepsy (e.g. temporal lobe epilepsy (TLE) and Dravet syndrome (DrS)), autism spectrum disorders (ASD) and Down syndrome (DoS)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2497525-96-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-172318. | |
| Ianalumab | Ianalumab (VAY-736) is a human, decarboxylated antibody against BAFF-R. Ianalumab can block the interaction between BAFF and BAFF-R and antagonize the apoptosis protection mediated by BAFF. Ianalumab exerts antibody-dependent cytotoxic (ADCC), depending on effector cell activation mediated by immune receptor tyrosine activation motif (ITAM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VAY-736. CAS No. 1929549-92-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99653. | |
| IAXO-102 | IAXO-102 is a TLR4 antagonist that modulates non-hematopoietic TLR4 proinflammatory signalling and inhibits experimental abdominal aortic aneurysm (AAA) development. Alternative Names: IAXO-102; 1115270-63-7; CID 25222900; (2R,3R,4S,5R,6S)-2-(aminomethyl)-6-methoxy-4,5-di(tetradecoxy)oxan-3-ol; CHEMBL493017; SCHEMBL20239315; EX-A3691; AKOS037648519; BS-14387; HY-125171; CS-0089755; D70080; Methyl 6-amino-6-deoxy-2,3-di-O-tetradecyl-|A-D-glucopyranoside. CAS No. 1115270-63-7. Molecular formula: C35H71NO5. Mole weight: 585.94. | |
| IAXO-102 | IAXO-102 is a TLR4 antagonist which negatively regulates TLR4 signalling. IAXO-102 inhibits MAPK and p65 NF-κB phosphorylation and expression of TLR4 dependent proinflammatory protein. IAXO-102 also prevents experimental abdominal aortic aneurysm development[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1115270-63-7. Pack Sizes: 10 mM * 1 mL in Ethanol; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125171. | |
| IB-00208 | IB-00208, a new cytotoxic polycyclic xanthone produced by Actinomadura sp. It also has anti-Gram-positive bacteria activity (MIC=0.09-1.4 nmol/L). Molecular formula: C36H34O12. Mole weight: 658.65. | |
| Ibadronic Acid-d3 | Ibadronic Acid-d3. Alternative Names: [1-Hydroxy-3-(methyl-d3-pentylamino)propylidene]bisphosphnic Acid; P,P'-[1-Hydroxy-3-(methyl-d3-pentylamino)propylidene]bisphosphonic Acid; Ibandronate-d3. CAS No. 1130899-41-0. Product ID: ACM1130899410. Molecular formula: C9H20D3NO7P2. Mole weight: 322.25. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Ibalizumab | Ibalizumab (TMB-355) is a humanized anti-CD4 IgG4 monoclonal antibody. Ibalizumab prevents HIV cell entry by binding to CD4 receptor. Ibalizumab can be used for the research of infection, such as HIV-1 infection[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TMB-355; TNX-355. CAS No. 680188-33-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99028. | |
| Ibalizumab | Ibalizumab is a humanized anti-CD4 monoclonal antibody approved for the treatment of HIV-1 infection. Ibalizumab blocks HIV-1 entry into CD4 cells while preserving normal immune function. Alternative Names: TMB-355; TNX-355. CAS No. 680188-33-4. Molecular formula: C14H9I3O4. Mole weight: 621.93. | |
| Ib-AMP1 | Ib-AMP1 is an antibacterial peptide isolated from Impatiens balsamina. It has activity against gram-positive bacteria and fungi. Alternative Names: IBAMP1; Basic peptide AMP1; Gln-Trp-Gly-Arg-Arg-Cys-Cys-Gly-Trp-Gly-Pro-Gly-Arg-Arg-Tyr-Cys-Val-Arg-Trp-Cys. | |
| Ib-AMP2 | Ib-AMP2 is an antibacterial peptide isolated from Impatiens balsamina. It has activity against bacteria and fungi. Alternative Names: IBAMP2; Basic peptide AMP2; Gln-Tyr-Gly-Arg-Arg-Cys-Cys-Asn-Trp-Gly-Pro-Gly-Arg-Arg-Tyr-Cys-Lys-Arg-Trp-Cys. | |
| Ib-AMP3 | Ib-AMP3 is an antibacterial peptide isolated from Impatiens balsamina. It has activity against bacteria and fungi. Alternative Names: IBAMP3; Basic peptide AMP3; Gln-Tyr-Arg-His-Arg-Cys-Cys-Ala-Trp-Gly-Pro-Gly-Arg-Lys-Tyr-Cys-Lys-Arg-Trp-Cys. | |
| Ib-AMP4 | Ib-AMP4 is an antibacterial peptide isolated from Impatiens balsamina. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: IBAMP4; Basic peptide AMP4; Gln-Trp-Gly-Arg-Arg-Cys-Cys-Gly-Trp-Gly-Pro-Gly-Arg-Arg-Tyr-Cys-Arg-Arg-Trp-Cys. | |
| Ibandronate Impurity 10 | Ibandronate Impurity 10. Uses: For analytical and research use. CAS No. 905808-25-5. Molecular formula: C8H21NO7P2. Mole weight: 305.2. Catalog: APB905808255. |  |
| Ibandronate Impurity 11 | Ibandronate Impurity 11. Uses: For analytical and research use. Molecular formula: C9H23NO8P2. Mole weight: 335.23. Catalog: APB11733. | |
| Ibandronate Impurity 12 | Ibandronate Impurity 12. Uses: For analytical and research use. Molecular formula: C11H17NO8P2. Mole weight: 353.2. Catalog: APB11734. | |
| Ibandronate Impurity 13 | Ibandronate Impurity 13. Uses: For analytical and research use. CAS No. 40870-84-6. Molecular formula: C9H19NO2. Mole weight: 173.26. Catalog: APB40870846. | |
| Ibandronate Impurity 2 | Ibandronate Impurity 2. Uses: For analytical and research use. CAS No. 2377035-78-2. Molecular formula: C8H18ClNO2. Mole weight: 195.69. Catalog: APB2377035782. | |
| Ibandronate Impurity 5 | Ibandronate Impurity 5. Uses: For analytical and research use. CAS No. 26153-88-8. Molecular formula: C7H17N. Mole weight: 115.22. Catalog: APB26153888. | |
| Ibandronate Impurity 6 | Ibandronate Impurity 6. Uses: For analytical and research use. Molecular formula: C11H22ClNO4. Mole weight: 267.75. Catalog: APB11732. | |
| Ibandronate Impurity 7 | Ibandronate Impurity 7. Uses: For analytical and research use. Molecular formula: C13H25NO4. Mole weight: 259.35. Catalog: APB11731. | |
| Ibandronate Impurity 9 | Ibandronate Impurity 9. Uses: For analytical and research use. CAS No. 1859096-06-2. Molecular formula: C1613C5H27N7O14P2. Mole weight: 668.39. Catalog: APB1859096062. | |
| Ibandronate Related Compound A | Ibandronate Related Compound A. Uses: For analytical and research use. CAS No. 625120-81-2. Mole weight: 209.71. Catalog: AP625120812. | |
| Ibandronate sodium | Ibandronate sodium. Group: Biochemicals. Grades: Highly Purified. CAS No. 138844-81-2. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C9H22NNaO7P2. US Biological Life Sciences. | Worldwide |
| Ibandronate sodium impurity 1 | Ibandronate sodium impurity 1. Uses: For analytical and research use. Molecular formula: C11H29NO14P4. Mole weight: 523.24. Catalog: APB11729. | |
| Ibandronate sodium impurity 3 | Ibandronate sodium impurity 3. Uses: For analytical and research use. CAS No. 953805-81-7. Molecular formula: C8H20NNaO7P2. Mole weight: 327.19. Catalog: APB953805817. | |
| Ibandronate sodium impurity 4 | Ibandronate sodium impurity 4. Uses: For analytical and research use. Molecular formula: C4H12NNaO7P2. Mole weight: 271.08. Catalog: APB11730. | |
| Ibandronate sodium monohydrate | Ibandronate sodium monohydrate. Group: Biochemicals. Alternative Names: BM-21.0955; Bondronat. Grades: Highly Purified. CAS No. 138926-19-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C9H24NNaO8P2. US Biological Life Sciences. | Worldwide |
| Ibandronate Sodium Monohydrate | Ibandronate Sodium Monohydrate (BM-210955; RPR-102289A) is an orally active, selective inhibitor of farnesyl pyrophosphate synthase (FPP synthase). Ibandronate Sodium Monohydrate can block the mevalonate pathway to inhibit the isoprenylation modification of small GTPases (such as RAS, RHO family proteins), induce tumor cell apoptosis and inhibit bone resorption. Ibandronate Sodium Monohydrate inhibits tumor cell proliferation (such as ER+ breast cancer cells), promotes the expression of the pro-apoptotic gene FAS, and can produce synergistic anti-tumor effects with anti-estrogen compounds. Ibandronate Sodium Monohydrate is used in the study of osteoporosis and bone metastatic tumors (such as breast cancer bone metastasis)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BM-210955; RPR-102289A. CAS No. 138926-19-9. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg. Product ID: HY-B0515. | |
| Ibandronate Sodium Monohydrate | Ibandronate (< 100 μM) inhibits growth of both prostate cancer cell lines (LNCaP and PC-3) in a dose dependent manner. Alternative Names: BM-21.0955. Grades:>98%. CAS No. 138926-19-9. Molecular formula: C9H23NO7P2.Na.H2O. Mole weight: 360.23. | |
| Ibandronate sodium salt | 5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C9H22NNaO7P2. CAS No. 138926-19-9. Prepack ID 46946205-5g. Molecular Weight 341.21. See USA prepack pricing. |  |
| Ibandronate sodium salt | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C9H22NNaO7P2. CAS No. 138926-19-9. Prepack ID 46946205-1g. Molecular Weight 341.21. See USA prepack pricing. | |
| Ibandronic acid | Ibandronic acid. Group: Biochemicals. Alternative Names: P, P'- [1-Hydroxy-3- (methylpentylamino) propylidene] bisphosphonic acid; [1-Hydroxy-3- (methylpentylamino) propylidene] bisphosphonic acid; BPH 24. Grades: Highly Purified. CAS No. 114084-78-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C9H23NO7P2. US Biological Life Sciences. | Worldwide |
| Ibandronic Acid-d3 | Labeled Ibandronic Acid. A bisphosphonate antiresorptive agent. Bone resorption inhibitor. Group: Biochemicals. Alternative Names: P, P'- [1-Hydroxy-3- [ (methyl-d3) pentylamino] propylidene] bisphosphonic Acid; [1-Hydroxy-3- [ (methyl-d3) pentylamino] propylidene] bisphosphonic Acid; BPH 24-d3; Ibandronate-d3; [1-Hydroxy-3- [ (methyl-d3) pentylamino] propylidene] diphosphonic Acid. Grades: Highly Purified. CAS No. 1130899-41-0. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| IBC 293 | IBC 293. Group: Biochemicals. Grades: Purified. CAS No. 306935-41-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ibentatug | Ibentatug is an anti-CSP1 human IgG1 κ monoclonal antibody[1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Category: Inhibitory antibodies. CAS No. 2767983-94-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990744. | |
| Iberdomide | Iberdomide (CC-220) is an orally active and potent cereblon (CRBN) E3 ligase modulator (CELMoD) with an IC50 of ~150?nM for cereblon-binding affinity. Iberdomide, a derivative of Thalidomide (HY-14658), has antitumor and immunostimulatory activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CC-220. CAS No. 1323403-33-3. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101291. | |
| Iberdomide (CC-220) | Iberdomide (CC-220) is a novel oral immunomodulatory compound that targets cereblon, part of the CRL4CRBN E3 ubiquitin ligase complex, with an IC50 of 60 nM in a competitive TR-FRET assay. Iberdomide (CC-220) induces apoptosis with antitumor and immunostimulatory activities. Group: Inhibitors. CAS No. 1323403-33-3. Pack Sizes: 2mg. Product ID: S8760. Formula: C25H27N3O5. Smiles: C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3OCC4=CC=C(C=C4)CN5CCOCC5. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| Iberin | Iberin. Group: Biochemicals. Alternative Names: 1-Isothiocyanato-3-(methylsulfinyl)-propane; 3-Methylsulfinylpropyl Isothiocyanate; NSC 321801. Grades: Highly Purified. CAS No. 505-44-2. Pack Sizes: 5mg. Molecular Formula: C5H9NOS2, Molecular Weight: 163.26. US Biological Life Sciences. | Worldwide |
| Iberiotoxin | Iberiotoxin is a toxin isolated from Buthus tamulus scorpion venom. Iberiotoxin is a selective high conductance high conductance Ca2+-activated K+ channel inhibitor with a Kd of ~1 nM. Iberiotoxin does not block other types of voltage-dependent ion channels[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 129203-60-7. Pack Sizes: 100 μg; 500 μg; 1 mg. Product ID: HY-P0190. | |
| Iberiotoxin | Iberiotoxin, a toxin extracted from the venom of the scorpion Buthus tamulus, is a selective blocker of high-conductance Ca2+-activated K+ channel. Alternative Names: Pyr-Phe-Thr-Asp-Val-Asp-Cys-Ser-Val-Ser-Lys-Glu-Cys-Trp-Ser-Val-Cys-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys-Met-Gly-Lys-Lys-Cys-Arg-Cys-Tyr-Gln-OH (Disulfide bridge: Cys7-Cys28, Cys13-Cys33, Cys17-Cys35); 5-Oxo-L-prolyl-L-phenylalanyl-L-threonyl-L-α-aspartyl-L-valyl-L-α-aspartyl-L-cysteinyl-L-seryl-L-valyl-L-seryl-L-lysyl-L-α-glutamyl-L-cysteinyl-L-tryptophyl-L-seryl-L-valyl-L-cysteinyl-L-lysyl-L-α-aspartyl-L-leucyl-L-phenylalanylglycyl-L-valyl-L-α-aspartyl-L-arginylglycyl-L-lysyl-L-cysteinyl-L-methionylglycyl-L-lysyl-L-lysyl-L-cysteinyl-L-arginyl-L-cysteinyl-L-tyrosyl-L-glutamine cyclic (7→28),(13→33),(17→35)-tris(disulfide); 4-L-aspartic acid-6-L-aspartic acid-8-L-serine-9-L-valine-18-L-lysine-19-L-aspartic acid-21-L-phenylalanine-22-glycine-23-L-valine-24-L-aspartic acid-30-glycine-37-L-glutamine-charybdotoxin. Grades: ≥96% by HPLC. CAS No. 129203-60-7. Molecular formula: C179H274N50O55S7. Mole weight: 4230.85. | |
| I-BET151 | I-BET151 (GSK1210151A) is a BET bromodomain inhibitor which inhibits BRD4, BRD2, and BRD3 with pIC50 of 6.1, 6.3, and 6.6, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GSK1210151A. CAS No. 1300031-49-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13235. | |
| I-BET151 | I-BET151 is a BET bromodomain inhibitor, which blocks recruitment of BET to chromatin. It was shown to induce early cell cycle arrest and apoptosis in human and mouse MLL-fusion leukemia cell lines. Alternative Names: GSK1210151A; 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one. Grades: >98%. CAS No. 1300031-49-5. Molecular formula: C23H21N5O3. Mole weight: 415.453. | |
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