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| Product | Description | |
|---|---|---|
| Ibuprofen sodium | Ibuprofen ((±)-Ibuprofen) sodium is an orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen sodium inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen sodium is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen sodium can be used in the research of pain, swelling, inflammation, infection, immunology, cancers[1][2][5][8]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Ibuprofen sodium. CAS No. 31121-93-4. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-78131C. |  |
| Ibuprofen (Standard) | Ibuprofen (Standard) is the analytical standard of Ibuprofen. This product is intended for research and analytical applications. Ibuprofen ((±)-Ibuprofen) is a potent, orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen ((±)-Ibuprofen) can be used in the research of pain, swelling, inflammation, infection, immunology, cancers[1][2][5][8]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Ibuprofen (Standard). CAS No. 15687-27-1. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-78131R. | |
| Ibutamoren | Ibutamoren (MK-677 free base; MK-0677 free base) is an orally active non-peptide growth hormone secretagogue receptor agonist. Ibutamoren activates signal cascades by mimicking endogenous ligands, triggers pulsatile release of growth hormone from the pituitary gland, and increases serum levels of IGF-1 and insulin-like growth factor-binding protein 3. Ibutamoren not only increases the frequency of growth hormone pulses in male individuals, but also promotes elevated bone formation markers in female individuals with postmenopausal osteoporosis. The combination of Ibutamoren with Alendronate sodium hydrate (HY-11101) significantly increases bone mineral density at the femoral neck. However, Ibutamoren may cause mild, reversible adverse reactions such as increased appetite, fluid retention, and elevated fasting blood glucose. Ibutamoren has been widely used in studies related to idiopathic growth hormone deficiency, sarcopenia, Alzheimer's disease, and osteoporosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-677 free base; MK-0677 free base. CAS No. 159634-47-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10199A. | |
| Ibutamoren Mesylate | Ibutamoren Mesylate (MK-677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist. Ibutamoren Mesylate is an orally active growth hormone (GH) secretagogue. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-677; MK-0677. CAS No. 159752-10-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-50844. | |
| Ibutilide fumarate | Ibutilide (U70226E) fumarate, an action potential-prolonging antiarrhythmic, is a potent blocker of the rapidly activating delayed rectifier K+ current (IKr) in AT-1 cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: U70226E. CAS No. 122647-32-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0387. | |
| Ibutilide Fumarate | A methanesulfonanilide antiarrhythmic agent; prologns myocardial action potential duration, predominantly by activation of slow inward sodium current. Antiarrhythmic (class III). Group: Biochemicals. Alternative Names: (+ / -) -N- [4- [4- (Ethylheptylamino) -1-hydroxybutyl] phenyl] methanesulfonamide. Grades: Highly Purified. CAS No. 122647-32-9. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Ibutilide Fumarate-d5 | Ibutilide Fumarate-d5. Group: Biochemicals. Alternative Names: (+ / -) -N- [4- [4- (Ethylheptylamino) -1-hydroxybutyl] phenyl] methanesulfonamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ibutilide fumarate impurity 1 | Ibutilide fumarate impurity 1. Uses: For analytical and research use. Molecular formula: C20H32N2O4S. Mole weight: 396.55. Catalog: APB12123. |  |
| Ibutilide fumarate impurity 2 | Ibutilide fumarate impurity 2. Uses: For analytical and research use. CAS No. 149684-23-1. Molecular formula: C17H18N2O6S2. Mole weight: 410.46. Catalog: APB149684231. | |
| Ibutilide fumarate impurity 3 | Ibutilide fumarate impurity 3. Uses: For analytical and research use. CAS No. 2340001-05-8. Molecular formula: C11H13NO5S. Mole weight: 271.29. Catalog: APB2340001058. | |
| Ibutilide fumarate impurity 4 | Ibutilide fumarate impurity 4. Uses: For analytical and research use. Molecular formula: C20H36N2O3S. Mole weight: 384.58. Catalog: APB12124. | |
| Ibutilide fumarate impurity 5 | Ibutilide fumarate impurity 5. Uses: For analytical and research use. CAS No. 100633-01-0. Molecular formula: C20H36N2O3S. Mole weight: 384.58. Catalog: APB100633010. | |
| i-Butylammonium Bromide | i-Butylammonium Bromide. Alternative Names: greatcell Solar, iso-Butylammonium Bromide, 2-Methylpropane-1-aminium Bromide. Mole weight: 154.05 g/mol. |  |
| i-Butylammonium Iodide | i-Butylammonium Iodide. Alternative Names: 2-Methylpropan-1-aminium Iodide, greatcell Solar, i-Butylamine hydrIodide. Molecular formula: C4H12IN. Mole weight: 201.05 g/mol. IUPAC Name: 2-methylpropan-1-amine;hydroiodide. SMILES: CC(C)CN.I. InChI: InChI=1S/C4H11N.HI/c1-4(2)3-5;/h4H,3,5H2,1-2H3;1H. | |
| i-Butyl isothiocyanate | i-Butyl isothiocyanate. Group: Thiocyanates Derivatives. Alternative Names: C5H9NS. CAS No. 591-82-2. |  Luxembourg Bio Technologies |
| Ibuzatrelvir | Ibuzatrelvir (PF-07817883), a second-generation, orally bioavailable, is SARS-CoV-2 main protease (Mpro and 3CLpro) inhibitor with improved metabolic stability. Ibuzatrelvir has demonstrated pan-human coronavirus antiviral activity and off-target selectivity profile in vitro and in preclinical animal studies. Ibuzatrelvir is well tolerated with a safety profile similar to placebo and prevents viral infection and transmission. Ibuzatrelvir can be used to inhibit COVID-19[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-07817883. CAS No. 2755812-39-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156654. | |
| IC-202-A | IC-202-A shows immunosuppressive activity, with IC50 of 3.6 μg/mL as determined by MLCR, and has a strong inhibitory effect on Blastogensis induced by ConA or lipopolysaccharide (LPS). Molecular formula: C27H52N6O7. Mole weight: 572.74. |  |
| IC202B | IC202B shows immunosuppressive activity, with IC50 of 3.6 μg/mL as determined by MLCR, and has a strong inhibitory effect on Blastogensis induced by ConA or lipopolysaccharide (LPS). Alternative Names: N-(5-aminopentyl)-N-hydroxy-N'-[5-(hydroxy{4-[(5-nitropentyl)amino]-4-oxobutanoyl}amino)pentyl]butanediamide; IC-202B. Molecular formula: C23H44N6O8. Mole weight: 532.63. | |
| IC261 | IC261 is a selective, ATP-competitive CK1 inhibitor, with IC50s of 1 μM, 1 μM, 16 μM for Ckiδ, Ckiε and Ckiα1, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 186611-52-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12774. | |
| IC-87114 | IC-87114 is a potent and selective PI3Kδ inhibitor with IC50 of 0.5 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 371242-69-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-10110. | |
| ICA 069673 | ICA 069673. Group: Biochemicals. Grades: Purified. CAS No. 582323-16-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ICA-069673 | ICA-069673 is a KCNQ2/Q3 potassium channel activator. ICA-069673 demonstrates greater selectivity for KV7.2/7.3 over KV7.3/KV7.5, with EC50s of 0.69 μM and 14.3 μM, respectively. ICA-069673 inhibits spontaneous phasic and nerve-evoked contractions in guinea pig detrusor smooth muscle (DSM). ICA-069673 also decreases the global intracellular Ca(2+) concentration in DSM cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 582323-16-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101396. | |
| ICA-069673 | ICA-069673 is an orally active, potent and selective KCNQ2/Q3 potassium channel activator (IC50= 0.69 μM) with 20-fold selectivity for KV7.2/KV7.3 over KV7.3/KV7.5 (EC50s = 14.3 μM). Alternative Names: ICA 069673; ICA069673. CAS No. 582323-16-8. Molecular formula: C11H6ClF2N3O. Mole weight: 269.63. | |
| ICA-105574 | ICA-105574 is a potent and efficacious hERG channel activator. The primary mechanism by which ICA-105574 potentiates hERG channel activity is by removing hERG channel inactivation. ICA-105574 steeply potentiates current amplitudes more than 10-fold with an EC50 value of 0.5 +/- 0.1 μM and a Hill slope (n(H)) of 3.3 +/- 0.2. ICA-105574 can prevent arrhythmias induced by cardiac delayed repolarization. ICA-105574 shortens action potential duration in ventricular myocytes concentration-dependently[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 316146-57-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124702. | |
| ICA-105665 | ICA-105665 (PF-04895162) is a potent and orally active neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels opener. ICA-105665 inhibits liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 μM). ICA-105665 can penetrate the blood-brain barrier and has antiseizure effects[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-04895162. CAS No. 2694728-63-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125469. | |
| ICA 110381 | ICA 110381. Group: Biochemicals. Grades: Purified. CAS No. 325457-99-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ICA 121431 | ICA 121431. Group: Biochemicals. Grades: Purified. CAS No. 313254-51-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ICA-121431 | ICA-121431 is a nanomolar potent and broad-spectrum voltage-gated sodium channel (Nav) blocker, shows equipotent selectivity for human Nav1.1 and Nav1.3 subtypes with IC50 values of 13 nM and 23 nM, respectively. ICA-121431 shows less potent inhibition of Nav1.2 (IC50=240 nM) and 1,000 fold selectivity against Nav1.4, Nav1.6, and the TTX-resistant human Nav1.5 and Nav1.8 channels (IC50s >10 μM). Uses: Scientific research. Category: Signaling pathways. CAS No. 313254-51-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-16787. | |
| ICA-27243 | ICA-27243 is a selective, potent and orally active KCNQ2/Q3 potassium channel opener with an EC50 of 0.38 μM. ICA-27243 is less effective at activating KCNQ4 and KCNQ3/Q5. ICA-27243 has antiepileptic and anticonvulsant effects[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 325457-89-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122114. | |
| Icapamespib | Icapamespib (PU-HZ151; PU-AD) is a selective, orally active inhibitor of Epichaperomes assembled by HSP90 with slow dissociation kinetics. Icapamespib can cross the blood-brain barrier (BBB) ??and induce epichaperome disassembly by non-covalently binding to HSP90, restoring the normal protein-protein interaction network. Icapamespib can specifically disrupt disease-related abnormal protein interaction networks, reduce neurotoxic protein aggregation and tumor cell survival signals. Icapamespib can be used in the research of neurodegenerative diseases such as Alzheimer's disease, as well as cancers such as glioblastoma and metastatic breast cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PU-HZ151. CAS No. 1000999-96-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137441. | |
| Icapamespib hydrochloride | Icapamespib (PU-HZ151; PU-AD) hydrochloride is a selective, orally active inhibitor of Epichaperomes assembled by HSP90 with slow dissociation kinetics. Icapamespib hydrochloride can cross the blood-brain barrier (BBB) ??and induce epichaperome disassembly by non-covalently binding to HSP90, restoring the normal protein-protein interaction network. Icapamespib hydrochloride can specifically disrupt disease-related abnormal protein interaction networks, reduce neurotoxic protein aggregation and tumor cell survival signals. Icapamespib hydrochloride can be used in the research of neurodegenerative diseases such as Alzheimer's disease, as well as cancers such as glioblastoma and metastatic breast cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PU-HZ151 hydrochloride. CAS No. 2267287-26-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137441A. | |
| Icaridin | Icaridin. CAS No. 119515-38-7. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  |
| Icariin | Icariin. Group: Biochemicals. Grades: Plant Grade. CAS No. 489-32-7. Pack Sizes: 20mg. Molecular Formula: C33H40O15, Molecular Weight: 676.66. US Biological Life Sciences. | Worldwide |
| Icariin | Icariin is a flavonol glycoside and a PDE5 inhibitor (IC50 = 5.9 μM) with 67-fold selectivity for PDE5 over PDE4. It exhibits antioxidant and anticancer activity. At a concentration of 1 x 107 mol/L, Icariin induces differentiation of cardiomyocytes and upregulates the expression of cardiac genes. At 20 μg/ml, Icariin increases the proliferation and differentiation of cultured human osteoblasts. Icariin affects the aging mechanism from different aspects, can delay the aging process and prevent the occurrence of senile diseases. Uses: Ingredient of health care products. Alternative Names: 3-[(6-Deoxy-a-L-mannopyranosyl)oxy]-7-b-D-glucopyranosyloxy-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one. Grades: ≥ 98%. CAS No. 489-32-7. Molecular formula: C33H40O15. Mole weight: 676.66. | |
| Icariin | Icariin is a flavonol glycoside. Icariin inhibits PDE5 and PDE4 activities with IC50s of 432 nM and 73.50 μM, respectively. Icariin also is a PPARα activator. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ieariline. CAS No. 489-32-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg. Product ID: HY-N0014. | |
| Icariside D2 | Icariside D2 is isolated from the fruits of Annona glabra. Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0±1.0?uM, and it induces apoptosis via alteration of expression of apoptosis-related proteins and decreased phosphorylation of AKT in HL-60 cells. Alternative Names: Icariside D2;38954-02-8;(2S,3R,4S,5S,6R)-2-[4-(2-hydroxyethyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol;IcarisideD2;CHEBI:182721;DTXSID001318054;HY-N7450;AKOS040761858;4-beta-D-Glucopyranosyloxybenzeneethanol;NCGC00385783-01;DA-54230;CS-0129180;G14608;4-(2-Hydroxyethyl)phenyl-beta-D-glucopyranoside;NCGC00385783-01_C14H20O7_4-(2-Hydroxyethyl)phenyl beta-D-glucopyranoside. Grades: 98.0%. CAS No. 38954-02-8. Molecular formula: C21H26N2O6. Mole weight: 402.4. | |
| Icariside E5 | Icariside E5 is a lignan glycoside isolated from the herbs of Epimedium brevicornu. It has antioxidant property that strengthens the importance of peppers in the Mediterranean diet. Uses: Antioxidant property. Alternative Names: 3-[4-β-D-Glucopyranosyloxy-5-methoxy-3-[2-(4-hydroxy-3-methoxyphenyl)-1-(hydroxymethyl)ethyl]phenyl]-2-propen-1-ol; 2-[(2R)-1-Hydroxy-3-(4-hydroxy-3-methoxyphenyl)-2-propanyl]-4-[(1 E)-3-hydroxy-1-propen-1-yl]-6-methoxyphenyl β-D-glucopyranoside. Grades: 93%. CAS No. 126176-79-2. Molecular formula: C26H34O11. Mole weight: 522.54. | |
| Icariside I | Icariside I Inhibitor. Uses: Scientific use. Product Category: T3808. CAS No. 56725-99-6. |  |
| Icariside I | Icariside I. Group: Biochemicals. Grades: Plant Grade. CAS No. 56725-99-6. Pack Sizes: 10mg. Molecular Formula: C27H30O11, Molecular Weight: 530.52. US Biological Life Sciences. | Worldwide |
| Icariside I | Icariside I is extracted from the herbs of Epimedium brevicornum Maxim. Alternative Names: Icariin I. Grades: >98%. CAS No. 56725-99-6. Molecular formula: C27H30O11. Mole weight: 530.5. | |
| Icariside II | A regulator of CXCR4 expression. Uses: Ingredient of health care products. Alternative Names: 3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one; Baohuoside 1; Baohuoside I; Baohuside I; Icariin II; Icariside II. Grades: 98%. CAS No. 113558-15-9. Molecular formula: C27H30O10. Mole weight: 514.52. | |
| Icaritin | Icaritin is unable to promote proliferation, migration and tube-like structure formation by human umbilical vein endothelial cells (HUVECs) in vitro. Icaritin potently inhibited proliferation of K562 cells (IC50 was 8 μM) and primary CML cells (IC50 was 13.4 μM for CML-CP and 18 μM for CML-BC), induced CML cells apoptosis and promoted the erythroid differentiation of K562 cells with time-dependent manner. Furthermore, Icaritin was able to suppress the growth of primary CD34+ leukemia cells (CML) and Imatinib-resistant cells, and to induce apoptosis. Icaritin strongly inhibited the growth of breast cancer MDA-MB-453 and MCF7 cells. At concentrations of 2-3 μM, icaritin induced cell cycle arrest at the G(2)/M phase accompanied by a down-regulation of the expression levels of the G(2)/M regulatory proteins such as cyclinB, cdc2 and cdc25C. Icaritin at concentrations of 4-5 μM, however, induced apoptotic cell death characterized by the accumulation of the annexin V- and propidium iodide-positive cells, cleavage of poly ADP-ribose polymerase (PARP) and down-regulation of the Bcl-2 expression. In mouse leukemia model, Icaritin could prolong lifespan of NOD-SCID nude mice inoculated with K562 cells as effective as Imatinib without suppression of bone marrow. Icaritin could up-regulate phospho-JNK or phospho-C-Jun and down-regulate phospho-ERK, phospho-P-38, Jak-2, phospho-Stat3 and phospho-Akt expression with dose- or ti | |
| Icaritin | Icaritin (Anhydroicaritin) is a prenylflavonoid derivative from Epimedium brevicornuMaxim. and potently inhibits proliferation of K562 cells (IC50 of 8 μM) and primary CML cells (IC50 of 13.4 μM for CML-CP and 18 μM for CML-BC). Icaritin can regulate MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings, also enhances osteogenesis[1][2][3. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anhydroicaritin. CAS No. 118525-40-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0678. | |
| Icaritin | Icaritin. Group: Biochemicals. Alternative Names: 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 118525-40-9. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C21H20O6. US Biological Life Sciences. | Worldwide |
| Icaritin (Anhydroicaritin) | Icaritin (Anhydroicaritin). Group: Biochemicals. Grades: Plant Grade. CAS No. 118525-40-9. Pack Sizes: 20mg. Molecular Formula: C21H20O6, Molecular Weight: 368.38. US Biological Life Sciences. | Worldwide |
| Icaritin Liposome (PEGylated) | Icaritin is a natural flavonoid compound that exhibits anticancer effects on various tumors, including hematologic malignancies such as leukemia, lymphoma, and multiple myeloma. This product is a pre-formulated liposome encapsulating Icaritin. It is only for research purposes. Group: Drug-loaded liposome. |  |
| i-Carradecaitoldecasulfate decasodium salt | i-Carradecaitoldecasulfate decasodium salt is a groundbreaking biomedical compound which can inhibit designated enzymes responsible for exacerbating cancer cell proliferation. It aids in studying lung, breast and prostate malignancies. Molecular formula: C60H84O72S10Na10. Mole weight: 2507.82. | |
| i-Carrahexaitol hexasulfate hexasodium salt | i-Carrahexaitol hexasulfate hexasodium salt is a derivative derived from i-Carrahexaitol, offering unprecedented opportunities for studying a multitude of diseases and conditions such as drug-resistant cancers and inflammatory disorders. Alternative Names: Iota-Carrahexaitol-Hexasulfate Hexasodium Salt. Molecular formula: C36H52O44S6Na6. Mole weight: 1519.11. | |
| i-Carrahexaose hexasulfate hexasodium salt | i-Carrahexaose hexasulfate hexasodium salt, an innovative biomedical substance, stands as a formidable solution against an array of ailments. By virtue of its unrivaled chemical configuration, it exhibits an outstanding capacity to impede the replication of notorious infectious agents such as HIV, influenza, and herpes viruses. Moreover, this extraordinary therapeutic treasure finds application in tackling inflammatory disorders and combating cancer. Alternative Names: Iota-Carrahexaose-Hexasulfate Hexasodium Salt. Molecular formula: C36H50O43S6Na6. Mole weight: 1501.09. | |
| i-Carraoctaitol octasulfate octasodium salt | i-Carraoctaitol octasulfate octasodium salt, an eminent biomedicine product, distinguishes itself as a paramount entity employed in the amelioration of diverse maladies. Exhibiting efficacy across ailments such as cancer, cardiovascular disorders, and inflammatory diseases, this multifaceted compound assumes the role of a commendable therapeutic intervention. Alternative Names: Iota-Carraoctaitol 12,24,32,44,52,64,72,84-octasulfate octasodium salt; Iota-Carraoctaitol-Octasulfate Octasodium Salt. Molecular formula: C48H68O58S8Na8. Mole weight: 2013.46. | |
| i-Carratetraitol tetrasulfate tetrasodium salt | i-Carratetraitol tetrasulfate tetrasodium salt is an extraordinary pharmaceutical compound extensively employed in the biomedical sphere. This exceptional substance showcases unparalleled efficiency in studying enduring inflammatory ailments, such as arthritand asthma. Alternative Names: Iota-Carratetraitol-Tetrasulfate Tetrasodium Salt. Molecular formula: C24H36O30S4Na4. Mole weight: 1024.75. | |
| i-Carratetraose tetrasulfate tetrasodium salt | i-Carratetraose tetrasulfate tetrasodium salt is a potent biomedical compound used in the treatment of various inflammatory conditions and autoimmune diseases. It exhibits excellent anti-inflammatory properties by effectively inhibiting the activation of pro-inflammatory cytokines. This product acts as a therapeutic agent to alleviate symptoms associated with conditions such as rheumatoid arthritis and Crohn's disease while promoting immune modulation. Alternative Names: Iota-Carratetraose-Tetrasulfate Tetrasodium Salt. Molecular formula: C24H34O29S4Na4. Mole weight: 1006.73. | |
| Icatibant | Icatibant(HOE-140) is a selective and specific antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively. Uses: Anti-inflammatory agents, non-steroidal. Alternative Names: L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-; H-D-Arg-Arg-Pro-Hyp-Gly-2Thi-Ser-D-Tic-Oic-Arg-OH; D-Arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-L-arginine; HOE140; HOE 140; HOE-140. Grades: >98%. CAS No. 130308-48-4. Molecular formula: C59H89N19O13S. Mole weight: 1304.52. | |
| Icatibant | Icatibant (HOE-140) is a potent and specific peptide antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HOE 140. CAS No. 130308-48-4. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-17446. | |
| Icatibant acetate | Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC50 and Ki of 1.07 nM and 0.798 nM respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HOE 140 acetate. CAS No. 138614-30-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108896. | |
| Icatibant Acetate | Icatibant acetate is a selective antagonist of bradykinin B2 receptors. Icatibant is a medication approved for the treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency. Uses: Anti-inflammatory agents, non-steroidal. Alternative Names: HOE 140 Acetate; HOE140 Acetate; HOE-140 Acetate; L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (1:x); H-D-Arg-Arg-Pro-Hyp-Gly-2Thi-Ser-D-Tic-Oic-Arg-OH.CH3CO2H; L-Arginine, D-arginyl-L-arginyl-L-prolyl-trans-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3aβ,7aβ)-octahydro-1H-indole-2-carbonyl-, acetate (salt); Firazyr. Grades: ≥95%. CAS No. 138614-30-9. Molecular formula: C59H89N19O13S.xC2H4O2. Mole weight: 1304.52 (free base). | |
| Icatibant Acetate | Icatibant Acetate. Categories: icatibant acetate; hoe-140. |  CA, FL & NJ |
| ICBA | ICBA is a C60 derivative that can be synthesized from C60 and indene. It is an acceptor material with shallow lowest occupied molecular orbital(LUMO) which can be used to enhance the performance of polymeric solar cells(PSCs). Alternative Names: 1',1'',4',4''-Tetrahydro-di[1,4]methanonaphthaleno[1,2:2',3',56,60:2'',3''][5,6]fullerene-C60,C60 derivative, indene-C60 bisadduct. CAS No. 1207461-57-1. Molecular formula: C78H16. Mole weight: 952.99. Purity: >98.5%HPLC. SMILES: C1C2C3=CC=CC=C3C1C45C26C7=C8C9=C1C2=C3C%10=C9C9=C%11C%12=C%10C%10=C%13C%14=C%12C%12=C%15C%16=C(C4=C4C%17=C%16C%16=C%18C%19=C%17C%17=C%20C%21=C%19C%19=C%22C%23=C%21C%21=C(C1=C7C(=C%21%20)C6=C%174)C2=C%23C(=C3%10)C%221C%13(C2CC1C1=CC=CC=C21)C(=C%18%19)C%14=C%15%16)C(=C%12%11)C5=C98. InChI: InChI=1S/C78H16/c1-2-6-12-11(5-1)15-9-16(12)76-69-53-37-23-25-41-29(37)30-38-24-26-42(30)58-57(41)73-65-49(25)33-31-43-19-21-39-27-28-36-20-22-40(28)56-55(39)71(63(65)47(21)33)77-17-10-18(14-8-4-3-7-13(14)17)78(73,77)74(58)66-50(26)34(48(22)64(66)72(56)77)32-44(20)60(62(46(24)32)70(76)54(38)53)68-52(36)51(35(19)27)67(75(15,68)76)59(43)61(69)45(23)31/h1-8,15-18H,9-10H2. | |
| I-CBP112 | I-CBP112, a chemical probe, is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor, that inhibits the CBP/p300 bromodomains, enhances acetylation by p300. Uses: Scientific research. Category: Signaling pathways. CAS No. 1640282-31-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19541. | |
| ICEC-0942 | ICEC-0942 is a small-molecule cyclin-dependent kinase 7 (CDK7) inhibitor developed for cancer therapy. Preclinical study in Acute Myeloid Leukaemia (AML) models shows that ICEC-0942 effectively inhibits the proliferation of several AML cell lines and patient derived AML cells in vitro (IC50 = 0.15-2.6 μM). Uses: Anticancer drug. Alternative Names: CT7001; CT 7001; CT-7001; ICEC0942; ICEC0 942; ICEC0-942. CAS No. 1805833-75-3. Molecular formula: C22H30N6O. Mole weight: 394.52. | |
| Icenticaftor | Icenticaftor (QBW251) is an orally active CFTR channel potentiator, with EC50s of 79 nM and 497 nM for F508del and G551D CFTR, respectively. Icenticaftor can be used for chronic obstructive pulmonary disease (COPD) and cystic fibrosis research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: QBW251. CAS No. 1334546-77-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-109177. | |
| Icerguastat | Icerguastat (Sephin1), a derivative of Guanabenz lacking the α2-adrenergic activity, is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). Icerguastat inhibits eIF2α dephosphorylation, thereby prolonging the protective response. Anti-prion effect[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sephin1; IFB-088. CAS No. 951441-04-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111022. | |
| icFSP1 | icFSP1 is a potent ferroptosis suppressor protein-1 (FSP1) inhibitor. icFSP1 triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation, in synergism with GPX4 inhibition. icFSP1 induces ferroptosis. icFSP1 shows antitumor activity against melanoma.[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1115910-36-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-157068. | |
| ICG001 | ICG001 Inhibitor. Uses: Scientific use. Product Category: T2237. CAS No. 847591-62-2. | |
| ICG-001 | ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to CREB-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300. ICG-001 induces apoptosis. Group: Inhibitors. CAS No. 780757-88-2 (relative stereochemistry); 847591-62-2 (absolute stereochemistry). Pack Sizes: 5mg. Product ID: S2662. Formula: C33H32N4O4. Smiles: C1CN(C2CN(C(=O)C(N2C1=O)CC3=CC=C(C=C3)O)CC4=CC=CC5=CC=CC=C54)C(=O)NCC6=CC=CC=C6. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| ICG-001 | ICG-001 is an inhibitor of β-catenin/TCF mediated transcription. ICG-001 works by specifically binding to cyclic AMP response element-binding protein with an IC50 of 3 μM. ICG-001 selectively blocks the β-catenin/CBP interaction without interfering with the β-catenin/p300 interaction. Uses: Scientific research. Category: Signaling pathways. CAS No. 780757-88-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14428. | |
| ICG-amine | ICG amine, as a near-infrared fluorescent probe, binds to amino acid residues without condensing agents. ICG is a tricarbocyanine dye[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1686147-55-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-133884. | |
| ICG Azide | ICG Azide is a copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reagent of near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging. NIR fluorescence allows to observe the deep image from the surface of skin and being utilized in a wide range of research fields. The maxima of Ex/Em values are at 785/812 nm. ICG might be excited using 750-800 nm laser line or LED and displays excellent optical property. ICG azide couples with an alkyne to form 1,4-disubstituted 1,2,3-triazole inside of living systems without interfering native biochemical processes. Prior to perform CuAAC, counterpart alkyne functionality should be introduced onto biomolecule by means of chemical or genetic modification. We offer ICG azide as a click chemistry reagent dye for cellular imaging and nucleotide functionalization. Mole weight: 813.42. | |
| ICG-DBCO | ICG-DBCO is a near-infrared fluorescent dye that is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling.Ex/Em = 789/813 nm. Uses: Scientific research. Category: Signaling pathways. CAS No. 3024705-52-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-W588722. | |
| ICG@HESSS-DOX | Augment your research on Biodegradable Polymers with the reliable ICG@HESSS-DOX from CD Bioparticles Drug Delivery. Group: Gsh response. |  |
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