A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
ICMT-IN-24 is an inhibitor of ICMT (IC50=0.19 μM). CAS No. 1313603-10-9. Molecular formula: C22H28ClNO2. Mole weight: 373.92.
ICMT-IN-25
ICMT-IN-25 is an inhibitor of ICMT (IC50=0.025 μM). CAS No. 1313602-83-3. Molecular formula: C21H26ClNO. Mole weight: 343.89.
ICMT-IN-26
ICMT-IN-26 is an inhibitor of ICMT (IC50=0.36 μM). CAS No. 1313602-84-4. Molecular formula: C21H26ClNO. Mole weight: 343.89.
ICMT-IN-27
ICMT-IN-27 is an inhibitor of ICMT (IC50=0.1 μM). CAS No. 1313603-11-0. Molecular formula: C22H28FNO2. Mole weight: 357.46.
ICMT-IN-28
ICMT-IN-28 is an inhibitor of ICMT (IC50=0.008 μM). CAS No. 1313603-12-1. Molecular formula: C22H28FNO2. Mole weight: 357.46.
ICMT-IN-29
ICMT-IN-29 is an inhibitor of ICMT (IC50=0.019 μM). CAS No. 1313603-13-2. Molecular formula: C20H27NO2S. Mole weight: 345.50.
ICMT-IN-3
ICMT-IN-3 is an inhibitor of ICMT (IC50=0.015 μM). CAS No. 1313602-73-1. Molecular formula: C22H29NO2. Mole weight: 339.47.
ICMT-IN-30
ICMT-IN-30 is an inhibitor of ICMT (IC50=0.27 μM). CAS No. 1313603-14-3. Molecular formula: C19H25NOS. Mole weight: 315.47.
ICMT-IN-31
ICMT-IN-31 is an inhibitor of ICMT (IC50=0.0038 μM). CAS No. 1313603-15-4. Molecular formula: C19H24ClNOS. Mole weight: 349.92.
ICMT-IN-32
ICMT-IN-32 is an inhibitor of ICMT (IC50=0.777 μM). CAS No. 1313603-17-6. Molecular formula: C20H25NO2. Mole weight: 311.42.
ICMT-IN-33
ICMT-IN-33 is an inhibitor of ICMT (IC50=0.46 μM). CAS No. 1313603-20-1. Molecular formula: C20H24ClNO. Mole weight: 329.86.
ICMT-IN-34
ICMT-IN-34 is an inhibitor of ICMT (IC50=0.17 μM). CAS No. 1313602-85-5. Molecular formula: C21H25Cl2NO. Mole weight: 378.34.
ICMT-IN-35
ICMT-IN-35, a FTPA-triazole compound, is an ICMT inhibitor (IC50=0.8 μM). Molecular formula: C25H29N3O2S. Mole weight: 435.58.
ICMT-IN-36
ICMT-IN-36 is an inhibitor of ICMT (IC50=0.181 μM). CAS No. 1313602-86-6. Molecular formula: C21H25Cl2NO. Mole weight: 378.34.
ICMT-IN-37
ICMT-IN-37 is an inhibitor of ICMT (IC50=0.308 μM). CAS No. 1313602-87-7. Molecular formula: C22H28ClNO. Mole weight: 357.92.
ICMT-IN-38
ICMT-IN-38 is an inhibitor of ICMT (IC50=0.049 μM). CAS No. 1313602-88-8. Molecular formula: C22H28ClNO. Mole weight: 357.92.
ICMT-IN-39
ICMT-IN-39 is an inhibitor of ICMT (IC50=0.031 μM). CAS No. 1313602-64-0. Molecular formula: C22H29NO. Mole weight: 323.47.
ICMT-IN-4
ICMT-IN-4 is an inhibitor of ICMT (IC50=0.27 μM). CAS No. 1313602-74-2. Molecular formula: C22H29NO2. Mole weight: 339.47.
ICMT-IN-40
ICMT-IN-40 is an inhibitor of ICMT (IC50=0.031 μM). CAS No. 1313602-65-1. Molecular formula: C22H29NO. Mole weight: 323.47.
ICMT-IN-41
ICMT-IN-41 is an inhibitor of ICMT (IC50=0.069 μM). CAS No. 1313602-66-2. Molecular formula: C23H31NO. Mole weight: 337.50.
ICMT-IN-42
ICMT-IN-42 is an inhibitor of ICMT (IC50=0.054 μM). CAS No. 1313602-67-3. Molecular formula: C23H31NO. Mole weight: 337.50.
ICMT-IN-43
ICMT-IN-43 is an inhibitor of ICMT (IC50=0.04 μM). CAS No. 1313602-68-4. Molecular formula: C23H31NO. Mole weight: 337.50.
ICMT-IN-44
ICMT-IN-44 is an inhibitor of ICMT (IC50=0.167 μM). CAS No. 1313602-69-5. Molecular formula: C24H33NO. Mole weight: 351.52.
ICMT-IN-45
ICMT-IN-45 is an inhibitor of ICMT (IC50=0.132 μM). CAS No. 1313602-70-8. Molecular formula: C24H33NO. Mole weight: 351.52.
ICMT-IN-46
ICMT-IN-46 is an inhibitor of ICMT (IC50=0.556 μM). CAS No. 1313602-71-9. Molecular formula: C25H35NO. Mole weight: 365.55.
ICMT-IN-47
ICMT-IN-47 is an inhibitor of ICMT (IC50=0.76 μM). CAS No. 1313602-72-0. Molecular formula: C25H35NO. Mole weight: 365.55.
ICMT-IN-48
ICMT-IN-48 is an inhibitor of ICMT. CAS No. 337486-54-1. Molecular formula: C30H37NO5. Mole weight: 491.62.
ICMT-IN-49
ICMT-IN-49 is an inhibitor of ICMT (IC50=0.12 μM). CAS No. 303728-92-9. Molecular formula: C27H31NO3. Mole weight: 417.54.
ICMT-IN-5
ICMT-IN-5 is an inhibitor of ICMT (IC50=0.3 μM). CAS No. 1313602-92-4. Molecular formula: C22H28FNO. Mole weight: 341.46.
ICMT-IN-50
ICMT-IN-50 is an inhibitor of ICMT (IC50=0.31 μM). CAS No. 371940-21-5. Molecular formula: C27H31NO3. Mole weight: 417.54.
ICMT-IN-51
ICMT-IN-51 is an inhibitor of ICMT (IC50=0.55 μM). CAS No. 1313602-89-9. Molecular formula: C21H26FNO. Mole weight: 327.44.
ICMT-IN-52
ICMT-IN-52 is an inhibitor of ICMT (IC50=0.052 μM). CAS No. 1313602-90-2. Molecular formula: C21H26FNO. Mole weight: 327.44.
ICMT-IN-53
ICMT-IN-53 is an inhibitor of ICMT (IC50=0.96 μM). It has PAMPA permeability and antiproliferative activity. CAS No. 1443253-17-5. Molecular formula: C26H36FN3. Mole weight: 409.58.
ICMT-IN-54
ICMT-IN-54, an adamantyl analogue, is an ICMT inhibitor (IC50=12.4 μM). Synonyms: (R)-2-[(adamantane-1-carbonyl)-amino]-3-(3,7,11-trimethyl-dodeca-2,6,10-trienylsulfanyl)-propionic acid. CAS No. 908856-14-4. Molecular formula: C29H45NO3S. Mole weight: 487.74.
ICMT-IN-55
ICMT-IN-55 is an ICMT inhibitor with IC50=90 nM. CAS No. 1313602-77-5. Molecular formula: C22H26F3NO2. Mole weight: 393.44.
ICMT-IN-6
ICMT-IN-6 is an inhibitor of ICMT (IC50=0.09 μM). CAS No. 1313602-75-3. Molecular formula: C23H31NO2. Mole weight: 353.50.
ICMT-IN-7
ICMT-IN-7 is an inhibitor of ICMT (IC50=0.015 μM). CAS No. 1313603-21-2. Molecular formula: C23H31NO. Mole weight: 337.50.
ICMT-IN-8
ICMT-IN-8 is an inhibitor of ICMT (IC50=0.652 μM). CAS No. 1313602-76-4. Molecular formula: C23H31NO3. Mole weight: 369.50.
ICMT-IN-9
ICMT-IN-9 is an inhibitor of ICMT (IC50=0.16 μM). CAS No. 1313602-93-5. Molecular formula: C22H28FNO2. Mole weight: 357.46.
ICMT Inhibitor (Cysmethynil)
An inhibitor of protein prenylation. Cysmethynil is a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT) with antitumor activity in cancer cells. Cysmethynil treatment results in inhibition of cell growth in an Icmt-dependent fashion, demonstrating mechanism-based activity of the compound. Treatment of cancer cells with cysmethynil results in mislocalization of Ras and impaired epidermal growth factor signaling. In a human colon cancer cell line, cysmethynil treatment blocks anchorage-independent growth, and this effect is reversed by overexpression of Icmt.A cell-permeable indole acetamide that acts as a substrate-competitive and AdoMet-noncompetitive Icmt.25uM) induces G1 cell cycle-arrest and autophagy-mediated, but not apoptotic, cell death in prostate cancer PC3 cells with concomitant PI 3-K/Akt and mTOR signaling blockage, consistent with inhibition of Icmt-mediated activation of Ras and Rheb GTPases. Murine PC3 xenograft studies reveal limited in vivo efficacy. Group: Biochemicals. Alternative Names: Cysmethynil; 2-(5-(3-Methylphenyl)-1-octyl-1H-indol-3-yl)acetamide, 2-(1-Octyl-5-m-tolyl-1H-indol-3-yl) acetamide; Isoprenylcysteine Carboxyl Methyltransferase Inhibitor). Grades: Highly Purified. CAS No. 851636-83-4. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C25H32N2O, Molecular Weight: 376.5. US Biological Life Sciences.
Worldwide
Icofungipen
Icofungipen, a cyclic β-amino acid, is the representative of a novel class of antifungals, active against Candida. Its in vivo efficacy indicates its potential for the oral treatment of yeast infections. Synonyms: (1R,2S)-2-amino-4-methylidenecyclopentane-1-carboxylic acid; Cyclopentanecarboxylic acid, 2-amino-4-methylene-, (1R,2S)- (9CI); Icofungipen; PLD 118; PLD118; PLD-118; BAY 10-8888; BAY 108888; BAY108888. Grade: 95%. CAS No. 198022-65-0. Molecular formula: C7H11NO2. Mole weight: 141.167.
Icomethasone
Icomethasone is a metabolite of Mometasone Furoate (M4425). Group: Biochemicals. Alternative Names: (11 β,16α)-9-Chloro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione; Icometasone. Grades: Highly Purified. CAS No. 4647-20-5. Pack Sizes: 10mg. Molecular Formula: C22H29ClO5, Molecular Weight: 408.92. US Biological Life Sciences.
Worldwide
Icomethasone 21-Acetate
Icomethasone 21-Acetate. Group: Biochemicals. Alternative Names: Icometasone-21-acetate; 9-Chloro-11 β,17,21-trihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione; (11 β,16α)-21-(Acetyloxy)-9-chloro-11,17-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione. Grades: Highly Purified. CAS No. 24916-91-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Icomethasone 21-Mesylate
Icomethasone 21-Mesylate is a derivative of Icomethasone, used in the preparation of Mometasone. Group: Biochemicals. Alternative Names: (11 β , 16α ) -9-Chloro-11, 17-dihydroxy-16-methyl-21-[ (methylsulfonyl) oxy]pregna-1, 4-diene-3, 20-dione. Grades: Highly Purified. CAS No. 352315-75-4. Pack Sizes: 10mg. Molecular Formula: C23H31ClO7S, Molecular Weight: 487.01. US Biological Life Sciences.
Worldwide
Icomethasone 21-Propionate
An impurity of Mometasone furoate, which is a topical corticosteroid used as an anti-inflammatory agent. Synonyms: 9-Chloro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-Propionate. CAS No. 107085-37-0. Molecular formula: C25H33ClO6. Mole weight: 464.98.
Icomidocholic acid
Icomidocholic acid (Aramchol) is a lipid molecule synthesized from cholic acid and arachidic acid. Icomidocholic acid is an orally active SCD1 inhibitor and cholesterol solubilizer with antifibrotic effects. Icomidocholic acid can reduce liver fat content, dissolve cholesterol crystals and prevent gallstone formation. Icomidocholic acid can be used in the study of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Aramchol; C20-FABAC. CAS No. 246529-22-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19796.
Icopezil maleate
The maleate salt form of Icopezil, a benzoxazol derivative, has been found to be an acetylcholinesterase inhibitor and was once studied for the treatment of Alzheimer's disease. It has already been discontinued by Pfizer. Synonyms: CP 118954-11; CP-118,954-11. UNII-1P15W0SPEN; Icopezil maleate [USAN]; Icopezil maleate (USAN); 145815-98-1; CHEMBL329012; CP 118954-11. Grade: 98%. CAS No. 145815-98-1. Molecular formula: C27H29N3O6. Mole weight: 491.54.
The enzyme, characterized from the plant Limnanthes douglasii (meadowfoam), is involved in the biosynthesis of (5Z)-icos-5-enoate, an unusual monounsaturated fatty acid that makes up to 60% of the total fatty acids in Limnanthes sp. seed oil. The enzyme only acts on saturated fatty acids. Group: Enzymes. Synonyms: acyl-CoA Δ5-desaturase (ambiguous). Enzyme Commission Number: EC 1.14.19.10. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0972; icosanoyl-CoA 5-desaturase; EC 1.14.19.10; acyl-CoA Δ5-desaturase (ambiguous). Cat No: EXWM-0972.
Icotinib
Icotinib (BPI-2009) is a potent, CNS-penetrant and specific EGFR inhibitor with an IC50 of 5 nM; also inhibits mutant EGFRL858R, EGFRL858R/T790M, EGFRT790M and EGFRL861Q. Icotinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BPI-2009. CAS No. 610798-31-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15164A.
Icotinib
Icotinib Hydrochloride (BPI-2009H), or Icotinib, is a highly selective, first generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). Synonyms: BPI-2009H. Grade: >98%. CAS No. 610798-31-7. Molecular formula: C22H21N3O4. Mole weight: 391.42.
Icotinib hydrochloride
Icotinib Hydrochloride is a quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), which is upregulated in a variety of cancer cell types. Icotinib supresses the cancer cell proliferation via EGFR tyrosine kinase inhibition. Synonyms: Icotinib HCl; BPI-2009; BPI 2009; BPI2009. Grade: >98%. CAS No. 1204313-51-8. Molecular formula: C22H22ClN3O4. Mole weight: 427.88.
Icotinib Impurity 1
Icotinib Impurity 1. Uses: For analytical and research use. CAS No. 1058651-74-3. Molecular formula: C22H21N3O5. Mole weight: 407.43. Catalog: APB1058651743.
Icotinib Impurity 10
Icotinib Impurity 10. Uses: For analytical and research use. CAS No. 2376901-56-1. Molecular formula: C20H21N3O5. Mole weight: 383.4. Catalog: APB2376901561.
Icotinib Impurity 11
Icotinib Impurity 11. Uses: For analytical and research use. CAS No. 2305154-39-4. Molecular formula: C17H12N4O2. Mole weight: 304.31. Catalog: APB2305154394.
Icotinib Impurity 12
Icotinib Impurity 12. Uses: For analytical and research use. CAS No. 610798-26-0. Molecular formula: C20H20ClN3O4. Mole weight: 401.85. Catalog: APB610798260.
Icotinib Impurity 13
Icotinib Impurity 13. Uses: For analytical and research use. CAS No. 610798-18-0. Molecular formula: C20H20BrN3O4. Mole weight: 446.3. Catalog: APB610798180.
Icotinib Impurity 14
Icotinib Impurity 14. Uses: For analytical and research use. CAS No. 1887066-23-0. Molecular formula: C22H25N3O5. Mole weight: 411.46. Catalog: APB1887066230.
Icotinib Impurity 15
Icotinib Impurity 15. Uses: For analytical and research use. CAS No. 1887066-21-8. Molecular formula: C20H21N3O4. Mole weight: 367.41. Catalog: APB1887066218.
Icotinib Impurity 16
Icotinib Impurity 16. Uses: For analytical and research use. CAS No. 1708935-17-4. Molecular formula: C19H15N3O3. Mole weight: 333.35. Catalog: APB1708935174.
Icotinib Impurity 17
Icotinib Impurity 17. Uses: For analytical and research use. CAS No. 2376901-55-0. Molecular formula: C20H21N3O5. Mole weight: 383.4. Catalog: APB2376901550.
Icotinib Impurity 18
Icotinib Impurity 18. Uses: For analytical and research use. CAS No. 1318600-04-2. Molecular formula: C22H23N3O6. Mole weight: 425.44. Catalog: APB1318600042.
Icotinib Impurity 19
Icotinib Impurity 19. Uses: For analytical and research use. CAS No. 1318600-10-0. Molecular formula: C22H25N3O6. Mole weight: 427.46. Catalog: APB1318600100.
Icotinib Impurity 2
Icotinib Impurity 2. Uses: For analytical and research use. CAS No. 1643673-64-6. Molecular formula: C22H20ClN3O4. Mole weight: 425.87. Catalog: APB1643673646.
Icotinib Impurity 20
Icotinib Impurity 20. Uses: For analytical and research use. CAS No. 1318600-06-4. Molecular formula: C22H23N3O6. Mole weight: 425.44. Catalog: APB1318600064.
Icotinib Impurity 21
Icotinib Impurity 21. Uses: For analytical and research use. CAS No. 1708935-20-9. Molecular formula: C21H19N3O4. Mole weight: 377.4. Catalog: APB1708935209.