A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Idebenone Impurity18. Uses: For analytical and research use. CAS No. 2435-54-3. Molecular formula: C6Br4O2. Mole weight: 432.68. Catalog: APB2435543.
Idebenone Impurity2
Idebenone Impurity2. Uses: For analytical and research use. CAS No. 88543-34-4. Molecular formula: C18H28O5. Mole weight: 324.42. Catalog: APB88543344.
Idebenone Impurity3
Idebenone Impurity3. Uses: For analytical and research use. CAS No. 88543-33-3. Molecular formula: C18H28O5. Mole weight: 324.42. Catalog: APB88543333.
Idebenone Impurity4
Idebenone Impurity4. Uses: For analytical and research use. Molecular formula: C19H32O5. Mole weight: 340.46. Catalog: APB11278.
Idebenone Impurity5
Idebenone Impurity5. Uses: For analytical and research use. Molecular formula: C19H31NO4. Mole weight: 337.46. Catalog: APB11275.
Idebenone Impurity6
Idebenone Impurity6. Uses: For analytical and research use. Molecular formula: C17H26O5. Mole weight: 310.39. Catalog: APB11276.
Idebenone Impurity7
Idebenone Impurity7. Uses: For analytical and research use. Molecular formula: C12H22O4. Mole weight: 230.3. Catalog: APB11277.
Idebenone Impurity8
Idebenone Impurity8. Uses: For analytical and research use. CAS No. 104967-07-9. Molecular formula: C22H34O6. Mole weight: 294.51. Catalog: APB104967079.
Idebenone Impurity9
Idebenone Impurity9. Uses: For analytical and research use. CAS No. 104966-92-9. Molecular formula: C21H32O6. Mole weight: 380.48. Catalog: APB104966929.
Idebenone Sulfate
Idebenone Sulfate is a potent biomedical product used to study the progression of neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. It exhibits antioxidant and neuroprotective properties. Synonyms: 10-(4,5-dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)decyl hydrogen sulfate; 319906-76-8. Grade: > 95%. CAS No. 319906-76-8. Molecular formula: C19H30O8S. Mole weight: 418.51.
Idebenone Sulfate-13C,d3 Potassium Salt
Idebenone Sulfate-13C,d3 Potassium Salt. Group: Biochemicals. Alternative Names: 2,3-Dimethoxy-5-methyl-6-[10-(sulfooxy)decyl]-2,5-cyclohexadiene-1,4-dione13C,d3 Potassium Salt. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C1813CH26D3KO8S, Molecular Weight: 460.6. US Biological Life Sciences.
Worldwide
Idebenone Sulfate-13C,d3 Potassium Salt
Isotope labelled Idebenone Sulfate is an analogue of Idebenone. It is an ubiquinone derivative with protective effects against cerebral ischemia. Idebenone Sulfate can be used for skin protection and regenerative purposes. Synonyms: 2,3-Dimethoxy-5-methyl-6-[10-(sulfooxy)decyl]-2,5-cyclohexadiene-1,4-dione13C,d3 Potassium Salt. Molecular formula: C18[13C]H26D3KO8S. Mole weight: 460.6.
Idelalisib
Idelalisib (CAL-101; GS-1101) is a highly selective and orally bioavailable p110δ inhibitor with an IC50 of 2.5 nM, showing 40- to 300-fold selectivity for p110δ over other PI3K class I enzymes. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CAL-101; GS-1101. CAS No. 870281-82-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13026.
Idelalisib
Idelalisib is a kinase inhibitor. In combination with rituximab, it was used for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL). Uses: The treatment of chronic lymphocytic leukemia (cll). Synonyms: Idelalisib; CAL101; CAL 101; CAL-101; GS1101; GS 1101; GS-1101, Idelalisib. Grade: > 95%. CAS No. 870281-82-6. Molecular formula: C22H18FN7O. Mole weight: 415.432.
Idelalisib-[d5]
Idelalisib-[d5] is the labelled analogue of Idelalisib. Idelalisib is a chemotherapy drug used for the treatment of relapsed chronic lymphocytic leukemia (CLL), follicular B-cell non-Hodgkin lymphoma and small lymphocytic lymphoma (SLL). Synonyms: Idelalisib D5. Grade: 95% by HPLC; 95% atom D. CAS No. 1830330-31-8. Molecular formula: C22H13D5FN7O. Mole weight: 420.45.
Idelalisib D5
Idelalisib D5, a version of Idelalisib marked with deuterium, is an orally bioavailable and highly selective inhibitor of p110δ. Category: Active pharmaceutical ingredients. Synonyms: CAL-101 D5, GS-1101 D5. CAS No. 1830330-31-8. Product ID: API1830330318. Molecular formula: C22H18FN7O. Mole weight: 420.45.
Idelalisib Metabolit
Idelalisib Metabolite is a metabolite of Idelalisib, a drug primarily employed in the treatment of chronic lymphocytic leukemia and follicular lymphoma. Synonyms: GS-563117. Grade: > 95%. Molecular formula: C22H18FN7O2. Mole weight: 431.43.
Idelalisib N-Glucuronide is an exclusive metabolite of Idelalisib, a prominent therapeutic agent for chronic lymphocytic leukemia (CLL), follicular lymphoma, and small lymphocytic lymphoma, exhibiting its efficacious function as a precise and strategic kinase inhibitor. Grade: > 95%. Molecular formula: C28H27FN7O7. Mole weight: 592.57.
IDF-11774
IDF-11774 is a hypoxia-inducible factor-1 (HIF-1) inhibitor. Study showed that IDF-11774 inhibited the accumulation of HIF-1α in vitro and in vivo in colorectal carcinoma HCT116 cells under hypoxic conditions, suppressing angiogenesis of cancer cells by reducing the expression of HIF-1 target genes. Synonyms: EX-A3002; 2-[4-(1-adamantyl)phenoxy]-1-(4-methylpiperazin-1-yl)ethanone. CAS No. 1429054-28-3. Molecular formula: C23H32N2O2. Mole weight: 368.51.
IDF-11774
IDF-11774 is a novel hypoxia-inducible factor α (HIFα)-1 inhibitor with an IC50 of 3.65?μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1429054-28-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-111387.
IDFP
IDFP is an organophosphorus compound that acts as an irreversible inhibitor of MAGL and FAAH with IC50 values of 0.8 and 3 nM, respectively. Inhibition of MAGL and FAAH increases anandamide and 2-AG in the brain, resulting in increased cannabinoid signaling and typical cannabinoid behavioral effects in animal studies. Synonyms: Isopropyl Dodecylfluorophosphonate; 1-[fluoro(propan-2-yloxy)phosphoryl]dodecane. Grade: ≥98%. CAS No. 615250-02-7. Molecular formula: C15H32FO2P. Mole weight: 294.4.
IDH1 Inhibitor 2
IDH1 Inhibitor 2 (compound 13) is a potent wild-type IDH1 inhibitor that exerts its activity through covalent modification of His315 with an IC50 value of 110 nM. IDH1 Inhibitor 2 can dose-dependently reduce the intracellular reduced glutamine metabolic flux, thereby affecting cellular metabolic homeostasis. IDH1 Inhibitor 2 can be used to study the role of IDH1 in cellular metabolic regulation and cancer development[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2244895-42-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-128661.
IDH1 Inhibitor 8
IDH1 Inhibitor 8 is an isocitrate dehydrogenase 1 (IDH1) inhibitor that can be used in cancer research. Synonyms: AG-120 Racemate; AG-120 (racemic); Ivosidenib (racemic); 1-(4-Cyano-2-pyridinyl)-5-oxo-L-prolyl-2-(2-chlorophenyl)-N-(3,3-difluorocyclobutyl)-N2-(5-fluoro-3-pyridinyl)glycinamide. Grade: 98%. CAS No. 1448346-63-1. Molecular formula: C28H22ClF3N6O3. Mole weight: 582.97.
IDH305
IDH305 is a potent, selective and brain penetrant inhibitor of mutant isocitrate dehydrogenase 1 (IDH1; IC50s = 27, 28, and 6,140 nM for recombinant IDH1R132H, IDH1R132C, and wild-type IDH1, respectively). It suppresses mutant IDH1-dependent 2-HG production and cell proliferation, and exhibits antitumor activity in preclinical studies. Synonyms: (4R)-4-[(1S)-1-fluoroethyl]-3-[2-({(1S)-1-[4-methyl-2'-(trifluoromethyl)[3,4'-bipyridin]-6-yl]ethyl}amino)pyrimidin-4-yl]-1,3-oxazolidin-2-one. Grade: ≥98%. CAS No. 1628805-46-8. Molecular formula: C23H22F4N6O2. Mole weight: 490.45.
IDH889
IDH889 is an orally available, brain penetrant, allosteric and mutant specific inhibitor of isocitrate dehydrogenase 1 (IDH1). IDH889 has potent selectivity for IDH1 R132* mutations, with IC50s of 0.02 μM, 0.072 μM and 1.38 μM for IDH1R132H, IDH1R132C and IDH1wt, respectively. IDH889 shows potent cellular inhibition of R-2-hydroxyglutarate (2-HG) production with an IC50 of 0.014 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1429179-07-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112289.
Idicalciferol impurity EDC-E
Idicalciferol impurity EDC-E. Uses: For analytical and research use. Molecular formula: C30H50O5. Mole weight: 490.73. Catalog: APB11284.
Idicalciferol impurity EDC-F
Idicalciferol impurity EDC-F. Uses: For analytical and research use. Molecular formula: C30H50O5. Mole weight: 490.73. Catalog: APB11283.
Idicalciferol impurity EDC-L
Idicalciferol impurity EDC-L. Uses: For analytical and research use. CAS No. 158689-03-3. Molecular formula: C30H50O5. Mole weight: 490.73. Catalog: APB158689033.
IDN-1965
IDN-1965 is a potent, broad-spectrum, irreversible caspase inhibitor. IDN-1965 is markedly effective at inhibiting Fas-mediated apoptosis by multiple routes of administration. The therapeutic potential of caspase inhibitors appears promising for the treatment of apoptosis-mediated liver injury based on potency and postinsult efficacy. Synonyms: IDN1965; IDN 1965; N-[(1,3-Dimethylindole-2-Carbonyl)Valinyl]-3-Amino-4-Oxo-5-Fluoropentanoic Acid; 3-((S)-2-(1,3-dimethyl-1H-indole-2-carboxamido)-3-methylbutanamido)-5-fluoro-4-oxopentanoic acid. Grade: 98%. CAS No. 204919-14-2. Molecular formula: C21H26FN3O5. Mole weight: 419.45.
IDO1 and HDAC1 Inhibitor
IDO1 and HDAC1 Inhibitor is a dual inhibitor of IDO1 and HDAC1 with IC50s of 69.0 nM and 66.5 nM, respectively. Synonyms: N-(2-Aminophenyl)-N'-[2-({4-[N-(3-bromo-4-fluorophenyl)-N'-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl}amino)ethyl]terephthalamide; 1,4-Benzenedicarboxamide, N1-(2-aminophenyl)-N4-[2-[[4-[(E)-[(3-bromo-4-fluorophenyl)amino](hydroxyimino)methyl]-1,2,5-oxadiazol-3-yl]amino]ethyl]-. CAS No. 2227044-16-6. Molecular formula: C25H22BrFN8O4. Mole weight: 597.40.
IDO1-IN-15
IDO1-IN-15 is an effective IDO1 inhibitor with IC50 of 127 nM. The potency of IDO1-IN-15 against IDO1 enzyme is comparable with Epacadostat in vitro. Category: Active pharmaceutical ingredients. CAS No. 2126853-17-4. Product ID: API2126853174. Molecular formula: C13H14BrFN6O3. Mole weight: 401.19.
IDO-IN-1
An IDO inhibitor with IC50 of 59 nM, showing activity in Hela cell (IC50 = 12 nM). Synonyms: IDO-IN-1; IDO-IN1; IDO-IN 1. Grade: > 98%. CAS No. 914638-30-5. Molecular formula: C9H7BrFN5O2. Mole weight: 316.09.
IDO-IN-13
IDO-IN-13 is an IDO1 inhibitor with EC50 of 17 nM. Grade: 98% by HPLC. CAS No. 2291164-02-6. Molecular formula: C26H17F3N4O. Mole weight: 458.4.
IDO-IN-2
IDO-IN-2 is a potent inhibitor of IDO (indoleamine-(2,3)-dioxygenase) with IC50 of 3 nM. Synonyms: IDO inhibitor 1; 1-[2-[bis(2-methylpropyl)amino]-5-[2-(2H-tetrazol-5-yl)phenyl]phenyl]-3-(4-methylphenyl)urea. CAS No. 1668565-74-9. Molecular formula: C29H35N7O. Mole weight: 497.63.
A potent IDO1 inhibitor with IC50 of 8 nM in human IDO1/HEK293 cells. Synonyms: IDO-IN-4; IDO-IN4; IDO-IN 4.(1R,2S)-2-(4-(diisobutylamino)-3-(3-(p-tolyl)ureido)phenyl)cyclopropanecarboxylic acid. Grade: > 98%. CAS No. 1629125-65-0. Molecular formula: C26H35N3O3. Mole weight: 437.57.
IDO-IN-5
A potent human IDO inhibitor with IC50 of 1-10 μM. Synonyms: IDO-IN-5; IDO-IN5; IDO-IN 5.(1R,4r)-4-((R)-2-((R)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexanol. Grade: > 98%. CAS No. 1402837-79-9. Molecular formula: C18H21FN2O2. Mole weight: 316.37.
IDO-IN-6
A potent human IDO inhibitor with IC50 of <1 μM. Synonyms: IDO-IN-6; IDO-IN6; IDO-IN 6.(1S,4r)-4-((S)-2-((S)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexanol. Grade:> 98%. CAS No. 1402837-76-6. Molecular formula: C18H21FN2O2. Mole weight: 316.37.
IDO-IN-7
A potent human IDO inhibitor with IC50 of <1 μM. Synonyms: IDO-IN-7; IDO-IN7; IDO-IN 7.(1R,4r)-4-((R)-2-((S)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexanol. Grade:> 98%. CAS No. 1402837-78-8. Molecular formula: C18H21FN2O2. Mole weight: 316.37.
IDO-IN-7
IDO-IN-7 (NLG-919 analogue) is a a potent IDO1 inhibitor with an IC50 of 38 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NLG-919 analogue; GDC-0919 analogue. CAS No. 1402836-58-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13983.
IDO-IN-8
A potent human IDO inhibitor with IC50 of 1-10 μM. Synonyms: IDO-IN-8; IDO-IN8; IDO-IN 8.(1S,4r)-4-((S)-2-((R)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexanol. Grade: > 98%. CAS No. 1402837-77-7. Molecular formula: C18H21FN2O2. Mole weight: 316.37.
IDOR-1117-2520
IDOR-1117-2520 is an orally active, potent, selective and reversible CCR6 antagonist. IDOR-1117-2520 antagonizes the CCL20-mediated calcium flow (IC50 = 63 nM) and inhibits β-arrestin recruitment to human CCR6 (IC50 = 30 nM) in cells expressing recombinant human CCR6. IDOR-1117-2520 is found to be a substrate of P-gp/MDR1. IDOR-1117-2520 can be used in the research of autoimmune diseases and skin inflammation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2737274-49-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-162495.
IDOR-4
IDOR-4 is a type IV CFTR corrector. IDOR-4 restores F508del-CFTR trafficking to the cell surface[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2839901-24-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-158002.
IDO/TDO-IN-1
IDO/TDO-IN-1 (compound 25) is a highly potent and orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor with IC50s of 9.7 and 47 nM, respectively [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2033173-01-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128355.
Idoxanthin
Idoxanthin. Group: Biochemicals. Alternative Names: (3RS,3'RS,4'RS)-Trihydroxy-b,b-caroten-4-one. Grades: Highly Purified. CAS No. 25510-19-4. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C40H54O4. US Biological Life Sciences.
Worldwide
Idoxifene
Idoxifene is a non-steroidal estrogen antagonist. It is also structurally analogous to tamoxifen. Idoxifene was both active and well tolerated in postmenopausal women with metastatic breast cancer. Idoxifene had similar efficacy and toxicity to tamoxifen in this randomized comparison. Synonyms: CB7432; 1-[2-[4-[(1E)-1-(4-Iodophenyl)-2-phenyl-1-buten-1-yl]phenoxy]ethyl]-pyrrolidine; trans-1-(4-Iodophenyl)-1-(4-(2'-pyrrolidinoethoxy)phenyl)-2-phenylbutene; (E)-1-[2-[4-[1-(4-iodophenyl)-2-phenyl-1-butenyl]phenoxy]ethyl]-pyrrolidine; SB 223030. Grade: ≥95%. CAS No. 116057-75-1. Molecular formula: C28H30INO. Mole weight: 523.45.
Idoxuridine
5-Iodo-2'-deoxyuridine is a nucleoside analog that can be incorporated into viral DNA replication to treat herpes simplex keratitis. Uses: 5-iodo-2'-deoxyuridine is a nucleoside analog treat herpes simplex keratitis. Synonyms: 5-Iodo-2'-deoxyuridine; IDU; 2'-Deoxy-5-iodouridine; 5-Iodo-2'-deoxy-D-uridine; 1-(2-Deoxy-β-D-ribofuranosyl)-5-iodouracil; IUdR; Dendrid; Emanil; NSC 39661; Ophthalmadine; Herpesil; Herpidu; Herplex; Stoxil; Stoxip; Synmiol; Virudox. Grade: ≥98% by HPLC. CAS No. 54-42-2. Molecular formula: C9H11IN2O5. Mole weight: 354.10.
Idoxuridine
Idoxuridine (5-Iodo-2-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC50 value of 4.3 μM[1]. Idoxuridine shows anti-orthopoxvirus activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-Iodo-2-deoxyuridine; 5-IUdR; IdUrd. CAS No. 54-42-2. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-B0307.
IDP TEA salt
IDP TEA salt is a pivotal constituent in the biomedical field, serving as a precursor for crucial molecules engaged in cellular processes. Its applied scope encompasses the synthesis of paramount compounds pertinent to studying viral invasions, immune disorders, and select cancerous conditions. Synonyms: Inosine-5'-diphosphate, triethylammonium salt; Inosine 5'-(trihydrogen diphosphate), triethylammonium salt (1:x); Inosine 5'-(trihydrogen diphosphate), triethylammonium salt; 5'-IDP triethylammonium salt; Inosine 5-diphosphate triethylammonium salt; Inosine diphosphate triethylammonium salt. Grade: ≥95% by HPLC. Molecular formula: C10H14N4O11P2 (free acid). Mole weight: 428.18 (free acid).
IDR-1
IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. CAS No. 940291-10-1. Molecular formula: C65H118N18O15. Mole weight: 242.31.
IDRA 21
IDRA 21. Group: Biochemicals. Grades: Purified. CAS No. 22503-72-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
IDRA-21
IDRA-21, an analog of cyclothiazide, inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. IDRA-21 inhibits synaptic and extrasynaptic NMDA receptor mediated events in cultured cerebellar granule cells. Synonyms: 7-Chloro-3-methyl-3-4-dihydro-2H-1,2,4 benzothiadiazine S,S-dioxide; IDRA-21; IDRA 21; IDRA21. CAS No. 22503-72-6. Molecular formula: C8H9ClN2O2S. Mole weight: 232.68.
Idrevloride
Idrevloride is an epithelial sodium channel (ENaC) inhibitor. Synonyms: 3,5-diamino-6-chloro-N-{[4-(4-{2-[(1-deoxy-D-glucitol-1-yl)(hexyl)amino]ethoxy}phenyl)butyl]carbamimidoyl} pyrazine-2-carboxamide; 3,5-diamino-6-chloro-N-[N'-[4-[4-[2-[hexyl-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]amino]ethoxy]phenyl]butyl]carbamimidoyl]pyrazine-2-carboxamide. CAS No. 1416973-63-1. Molecular formula: C30H49ClN8O7. Mole weight: 669.22.
IDT307
IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1141-41-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129096.
iduronate-2-sulfatase
Iduronate 2-sulfatase (IDS) is a sulfatase enzyme associated with Hunter syndrome. Group: Enzymes. Synonyms: chondroitinsulfatase; idurono-2-sulfatase; iduronide-2-sulfate sulfatase; L-iduronosulfatase; L-idurono sulfate sulfatase; iduronate sulfatase; sulfo-L-iduronate sulfatase; L-iduronate 2-sulfate sulfatase; sulfoiduronate sulfohydrolase; 2-sulfo-L-iduronate 2-sulfatase; iduronate-2-sulfate sulfatase; iduronate sulfate sulfatase. Enzyme Commission Number: EC 3.1.6.13. CAS No. 50936-59-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3746; iduronate-2-sulfatase; EC 3.1.6.13; 50936-59-9; chondroitinsulfatase; idurono-2-sulfatase; iduronide-2-sulfate sulfatase; L-iduronosulfatase; L-idurono sulfate sulfatase; iduronate sulfatase; sulfo-L-iduronate sulfatase; L-iduronate 2-sulfate sulfatase; sulfoiduronate sulfohydrolase; 2-sulfo-L-iduronate 2-sulfatase; iduronate-2-sulfate sulfatase; iduronate sulfate sulfatase. Cat No: EXWM-3746.
Iduronic acid
L-Iduronic acid is a crucial component in the biomedical industry used for various purposes. It is commonly employed in the synthesis of dermatan sulfate, a polysaccharide found in connective tissues. Additionally, L-Iduronic acid is utilized in the production of heparan sulfate, a glycosaminoglycan involved in different biological processes. Synonyms: d-iduronic acid; 3402-98-0; Iduronic acid, D-; (2S,3R,4R,5S)-2,3,4,5-tetrahydroxy-6-oxohexanoic acid; F5HD8XQ3DP; 8DWF4HK64B; 21675-53-6; UNII-F5HD8XQ3DP; UNII-8DWF4HK64B; IDURONIC ACID, DL-; SCHEMBL147158; DTXSID90187632; IAJILQKETJEXLJ-LECHCGJUSA-N; Q418846; W-202387. Grade: ≥95%. CAS No. 3402-98-0. Molecular formula: C6H10O7. Mole weight: 194.14.
IDX184
IDX184 is a potent and orally bioavailable HCV replication inhibitor that potently inhibits HCV polymerase with an IC50 of 0.31 μM and a Ki of 52.3 nM. Synonyms: Guanosine, 2'-C-methyl-, 5'-(2-((3-hydroxy-2,2-dimethyl-1-oxopropyl)thio)ethyl N-(phenylmethyl)phosphoramidate); 5'-O-[(Benzylamino)[2-(3-hydroxy-2,2-dimethylpropionylsulfanyl)ethoxy]phosphoryl]-2'-C-methylguanosine; 2'-C-Methylguanosine 5'-[2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)thio]ethyl N-(phenylmethyl)phosphoramidate]. Grade: ≥95%. CAS No. 1036915-08-8. Molecular formula: C25H35N6O9PS. Mole weight: 626.62.
IDX899
IDX899 is a novel next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI) with activity against efavirenz-resistant strains. It is used in the treatment of treatment-naive HIV-1-infected subjects. Uses: Idx899 is used in the treatment of treatment-naive hiv-1-infected subjects. Synonyms: GSK 224876 ; GSK-224876 ; GSK224876; IDX-899; IDX 899; IDX899; 5-Chloro-3-[[3-[(E)-2-cyanovinyl]-5-methyl-phenyl]-methoxy-phosphoryl]-1H-indole-2-carboxamide; Methyl (E)-(2-carbamoyl-5-chloro-1H-indol-3-yl)(3-(2-cyanovinyl)-5-methylphenyl)phosphinate; GSK-224876; GSK224876; (R,E)-methyl (2-carbamoyl-5-chloro-1H-indol-3-yl)(3-(2-cyanovinyl)-5-methylphenyl)phosphinate. Grade: 95%. CAS No. 1097733-15-7. Molecular formula: C20H17ClN3O3P. Mole weight: 413.79.
IEICO-4F
IEICO-4F. CAS No. 2089044-02-8. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
IEM 1460. Group: Biochemicals. Grades: Purified. CAS No. 121034-89-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
IEM 1460
IEM 1460, an adamantane derivative, is a selective and voltage-dependent open-channel antagonist of AMPA receptors. It is Ca2+ permeable and lacks GluR2 subunits. So it may be used to discriminat between AMPA receptors of different subunit composition. It selectively blocks fast spiking interneuron but not mediums spiny projection neuron in mouse striatum. It is used as an anticonvulsant in vivo. Synonyms: IEM 1460; IEM1460; IEM-1460; N,N,H,-Trimethyl-5-[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]-1-pentanaminiumbromide hydrobromide. Grade: ≥98% by HPLC. CAS No. 121034-89-7. Molecular formula: C19H38N2Br2. Mole weight: 454.33.
IEM-1460
IEM-1460 blocks both AMPA and NMDA glutamate receptor with anticonvulsant effect in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 121034-89-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103230.
IEM 1754 dihydrobromide
IEM 1754 dihydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 162831-31-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
IEM 1754 dihydrobromide
IEM 1754 causes use- and voltage-dependent block of open channels of recombinant AMPA receptors. Synonyms: IEM-1754 dihydrobromide; IEM1754 dihydrobromide; IEM-1754 2HBr; IEM 1754 2HBr; IEM1754 2HBr; N-(Tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1,5-pentanediamine dihydrobromide. Grade: >98%. CAS No. 162831-31-4. Molecular formula: C16H32Br2N2. Mole weight: 412.25.
IEM 1925 dihydrobromide
IEM 1925 dihydrobromide is the dihydrobromide salt of IEM 1925, which is a use- and voltage-dependent open-channel antagonist of AMPA receptors. It is selective between subtypes and blocks GluR2 subunit-lacking receptors more potently than GluR2-containing receptors and IEM 1754. It alleviates inflammatory pain in a rat model of peripheral inflammation. Synonyms: IEM 1925 dihydrobromide; IEM1925 dihydrobromide; IEM-1925 dihydrobromide; N-(1-Phenylcyclohexyl)-1,5-pentanediamine dihydrobromide. Grade: ≥98% by HPLC. CAS No. 258282-23-4. Molecular formula: C17H28N2.2HBr. Mole weight: 422.24.
IEM 1925 dihydrobromide
IEM 1925 dihydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 258282-23-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ieramilimab
Ieramilimab is a humanized monoclonal antibody that binds to LAG-3. Ieramilimab has been investigated as a cancer therapy. Synonyms: LAG525; IMP701. CAS No. 2137049-37-5.
Ifebemtinib
Ifebemtinib (BI 853520) is an orally active and potent focal adhesion kinase (FAK) inhibitor (recombinant FAK IC50=1 nM). Ifebemtinib shows anti-proliferative activity against cancer cells. Ifebemtinib inhibits FER Kinase and FES Kinase with IC50s of 900 nM and 1040 nM, respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BI-853520; IN-10018. CAS No. 1227948-82-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122844.