American Chemical Suppliers

A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.

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Product
iCRT 14 iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT), with IC50 of 40.3 nM against Wnt responsive STF16 luciferase. Uses: Scientific research. Category: Signaling pathways. CAS No. 677331-12-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16665. MedChemExpress MCE
iCRT3 iCRT3 is an inhibitor of both Wnt and β-catenin-responsive transcription. Uses: Scientific research. Category: Signaling pathways. CAS No. 901751-47-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103705. MedChemExpress MCE
Icrucumab Icrucumab (Anti-VEGFR1/FLT1 Reference Antibody; IMC-18F1) is an IgG1 antibody inhibitor targeting VEGFR-1/FLT1 with anti-tumor activity. By blocking ligand-dependent phosphorylation and downstream signal transduction, Icrucumab reduces the activities of MAPK and Akt in breast cancer xenograft models, inhibits the proliferation and invasion of VEGFR-1-positive tumor cells, and reverses the conversion of M1 macrophages to the pro-tumor M2-like phenotype. Icrucumab also inhibits tumor cell proliferation, promotes apoptosis, and effectively suppresses tumor growth through direct targeting of tumors and host support mechanisms. In addition, Icrucumab exhibits a synergistic effect when combined with chemotherapeutic agents, and it is used in research related to various cancers including advanced solid malignancies, thyroid cancer, melanoma, and lung cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anti-VEGFR1/FLT1 Reference Antibody; IMC-18F1. CAS No. 1024603-92-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99364. MedChemExpress MCE
ID-8 ID-8. Group: Biochemicals. Alternative Names: ID 8, 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol, AC1LGAMV, HY-15838. Grades: Highly Purified. CAS No. 147591-46-6. Pack Sizes: 25mg. Molecular Formula: C16 H14 N2O4, Molecular Weight: 298.3. US Biological Life Sciences. USBiological 11
Worldwide
IDA, 1-20 cps IDA, 1-20 cps. Mole weight: 212. Alfa Chemistry Materials 2
IDA, 2-8 cps IDA, 2-8 cps. Mole weight: 212. Alfa Chemistry Materials 2
Idactamab Idactamab (INT-001) is an IgG1-κ antibody with in vivo activity across a spectrum of hematological malignancies. Idactamab can be used for prepare MEDI7247, a potent and specific ADC, targeting ASCT2 (SLC1A5)[1][2]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: INT-001. CAS No. 2245205-37-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99654. MedChemExpress MCE
Idarubicin Idarubicin is an orally active and potent anthracycline antileukemic agent. Idarubicin inhibits the topoisomerase II interfering with the replication of DNA and RNA transcription. Idarubicin shows induction of DNA damage. Idarubicin inhibits DNA synthesis and of c-myc expression. Idarubicin inhibits the growth of bacteria and yeasts[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Demethoxydaunorubicin. CAS No. 58957-92-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17381A. MedChemExpress MCE
Idarubicin hydrochloride 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C26H27NO9. CAS No. 58957-92-9. Prepack ID 63240268-25mg. Molecular Weight 497.49. See USA prepack pricing. Molekula Americas
Idarubicin hydrochloride 10mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C26H27NO9. CAS No. 58957-92-9. Prepack ID 63240268-10mg. Molecular Weight 497.49. See USA prepack pricing. Molekula Americas
Idarubicin hydrochloride Idarubicin hydrochloride is an anthracycline antileukemic agent. It inhibits the topoisomerase II interfering with the replication of DNA and RNA transcription. Idarubicin hydrochloride inhibits the growth of bacteria and yeasts. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Demethoxydaunorubicin hydrochloride. CAS No. 57852-57-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17381. MedChemExpress MCE
Idarubicin Hydrochloride Orally active anthracycline; analog of Daunorubicin. Antineoplastic. Group: Biochemicals. Alternative Names: (7S,9S)-Hydrochloride; Idamycin; NSC 256439; Zavedos. Grades: Highly Purified. CAS No. 57852-57-0. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 11
Worldwide
Idarubicinol Idarubicinol is the alcohol analog of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. It is also an analog of Daunorubicin. Alternative Names: 5,12-Naphthacenedione, 7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1S)-1-hydroxyethyl]-, (7S,9S)-; (7S,9S)-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1S)-1-hydroxyethyl]-5,12-naphthacenedione; 5,12-Naphthacenedione, 7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-(1-hydroxyethyl)-, [7S-[7α,9α,9(R*)]]-; 13-Dihydroidarubicin; 4-Demethoxydaunorubicinol; Antibiotic FCE 22723. Grades: > 95%. CAS No. 86189-66-4. Molecular formula: C26H29NO9. Mole weight: 499.52. BOC Sciences 3
Idarubicinol-d4 Idarubicinol-d4 is a labelled Idarubicinol. Alternative Names: Idarubicinol-d4 (Mixture of Diastereomers); (7S,9S)-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1R*)-1-hydroxyethyl]-5,12-naphthacenedione-d4; [7S-[7α,9α,9(R*)]]-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopy. Grades: > 95%. Molecular formula: C26H25NO9D4. Mole weight: 503.55. BOC Sciences 3
Idarubicinol (Mixture of Diastereomers) Idarubicinol (Mixture of Diastereomers). Group: Biochemicals. Alternative Names: (7S,9S)-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1R*)-1-hydroxyethyl]-5,12-Naphthacenedione; [7S-[7α, 9α, 9(R*)]]-7-[(3-amino-2, 3, 6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7, 8, 9, 10-tetrahydro-6, 9, 11-trihydroxy-9-(1-hydroxyethyl)-5, 12-Naphthacenedione; 13-Dihydroidarubicin; 4-Demethoxydaunorubicino l; Antibiotic FCE 22723. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C26H29NO9, Molecular Weight: 499.51. US Biological Life Sciences. USBiological 11
Worldwide
Idarubicinone Idarubicinone is a derivative of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Alternative Names: 4-demethoxy daunomycinone; (7S,9S)-9-acetyl-6,7,9,11-tetrahydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione; 4-Demethoxydaunomycinone; Idarubicin aglycone; (+)-4-Demethoxydaunomycinone; 5,12-Naphthacenedione, 9-acetyl-7,8,9,10-tetrahydro-6,7,9,11-tetrahydroxy-, (7S-cis)-; (+)-Idarubicinone; (8S,10S)-7,8,9,10-Tetrahydro-6,8,10,11-tetrahydroxy-8-acetyl-5,12-naphthacenedione. Grades: ≥95%. CAS No. 60660-75-5. Molecular formula: C20H16O7. Mole weight: 368.34. BOC Sciences 11
Idasanutlin Idasanutlin (RG7388) is a potent and selective MDM2 antagonist, inhibiting p53-MDM2 binding, with an IC50 of 6 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RG7388. CAS No. 1229705-06-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15676. MedChemExpress MCE
Idasanutlin Idasanutlin; also known as RG7388 and RO5503781, is a highly potent and selective MDM2 antagonist with potential anticancer activity. RG7388 binds to MDM2 blocking the interaction between the MDM2 protein and the transcriptional activation domain of the tumor suppressor protein p53. By preventing the MDM2-p53 interaction, p53 is not enzymatically degraded and the transcriptional activity of p53 is restored. This may lead to p53-mediated induction of tumor cell apoptosis. MDM2, a zinc finger nuclear phosphoprotein and negative regulator of the p53 pathway, is often overexpressed in cancer cells and has been implicated in cancer cell proliferation and survival. Uses: For research used only. Alternative Names: RG7388; RG 7388; RG-7388; RO5503781; RO-5503781; RO 5503781. Grades: >98%. CAS No. 1229705-06-9. Molecular formula: C31H29Cl2F2N3O4. Mole weight: 616.487. BOC Sciences 3
Idazoxan hydrochloride Idazoxan hydrochloride. Uses: For analytical and research use. CAS No. 79944-56-2. Mole weight: 240.69. Catalog: AP79944562. Alfa Chemistry Analytical Products
Idazoxan hydrochloride Idazoxan hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 79944-56-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 11
Worldwide
Idazoxan hydrochloride Idazoxan hydrochloride (RX 781094 hydrochloride) is an α2-adrenoceptor antagonist and is also a imidazoline receptors (IRs) antagonist competitively antagonized the centrally induced hypotensive effect of imidazoline-like agents (IMs). Idazoxan hydrochloride also improves motor symptoms in Parkinsons disease, L-DOPA-induced dyskinesias, and experimental Parkinsonism[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RX 781094 hydrochloride. CAS No. 79944-56-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-14561A. MedChemExpress MCE
IDE1 IDE1 is an inducer of definitive endoderm 1. Uses: Scientific research. Category: Signaling pathways. CAS No. 1160927-48-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100533. MedChemExpress MCE
IDE-1 IDE-1 was identified in a high throughput screen as an inducer of definitive endoderm (IDE) from embryonic stem (ES) cells. IDE-1 is able to generate Sox17+/FoxA2+ cells to an equal or greater efficiency than that of protein (i.e. Activin A or Nodal) IDEs in mouse or human ES cell cultures. It functions in part via activation of TGF-β signaling, as evident by Smad2 phosphorylation. IDE-1 chemically induced endoderm can continue to differentiate into pancreatic progenitors in vitro and contribute to gut tube formation in vivo when injected into the developing gut tube of mouse embryos. Uses: Differentiation. Alternative Names: 7-[2-(2-Carboxybenzylidene)hydrazinyl]-7-oxoheptanoic acid; IDE1; IDE-1; IDE 1. Grades: 0.98. CAS No. 1160927-48-9. Molecular formula: C15H18N2O5. Mole weight: 306.31. BOC Sciences 12
IDE 2 IDE2 is a small molecule cell-permeable inducer of definitive endoderm formation in mouse and human embryonic stem cells (ESCs) by activating the TGF-βsignaling pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1136466-93-7. Pack Sizes: 1 mg. Product ID: HY-100534. MedChemExpress MCE
Idebenone Idebenone is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant. Idebenone is a smart promoting drug, which is mainly used in the treatment of many degenerative diseases of the central nervous system related to oxidative compressions, such as Parkinson's disease, Alzheimer's disease, multi-infarct dementia, cerebral anemia and cerebral failure, and is also used in the treatment of Friedreich's ataxia. It can also be used in cosmetic formulations to clear free radicals, inhibit lipid peroxidation, inhibit inflammation, inhibit DNA damage, photoprotection, reduce pigmentation, and other cosmetic effects. Alternative Names: CV 2619; CV-2619; CV2619; Catena; Raxone; Sovrima; 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione; 2,3-Dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone; 2-(10-Hydroxy-decyl)-5,6-dimethoxy-3-methyl-[1,4]benzoquinone; Avan; Daruma; Hydroxydecyl ubiquinone; Mnesis. Grades: >98%. CAS No. 58186-27-9. Molecular formula: C19H30O5. Mole weight: 338.44. BOC Sciences
Idebenone Ubiquinone derivative with protective effects against cerebral ischemia. Nootropic. Group: Biochemicals. Alternative Names: 2-(10-Hydroxydecyl)-5,6-methoxy-3-methyl-2,5-cyclohexadiene-1,4-dione; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone; Avan; CV 2619; Daruma; Idebenone; Mnesis. Grades: Highly Purified. CAS No. 58186-27-9. Pack Sizes: 100mg. US Biological Life Sciences. USBiological 11
Worldwide
Idebenone Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC50=16.65 μM)[1]. Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells[2]. Idebenone quickly crosses the blood-brain barrier. Uses: Scientific research. Category: Signaling pathways. CAS No. 58186-27-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0303. MedChemExpress MCE
Idebenone > 98% Idebenone > 98%. CAS No. 58186-27-9. Pharma Resources International LLC
CA, FL & NJ
Idebenone Glucuronide-13C,d3 Idebenone Glucuronide-13C,d3. Group: Biochemicals. Alternative Names: 2-(10-Hydroxydecyl)-5,6-methoxy-3-methyl-2,5-cyclohexadiene-1,4-dione β-D-Glucopyranosiduronic Acid-13C,d3; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone β-D-Glucopyranosiduronic Acid-13C,d3; Avan Glucuronide-13C,d3; CV 2619 Glucuronide-13C,d3; Daruma Glucuronide-13C,d3; Mnesis Glucuronide-13C,d3. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C2413CH35D3O11, Molecular Weight: 518.57. US Biological Life Sciences. USBiological 11
Worldwide
Idebenone Impurity1 Idebenone Impurity1. Uses: For analytical and research use. Molecular formula: C19H31NO4. Mole weight: 337.46. Catalog: APB11274. Alfa Chemistry Analytical Products 2
Idebenone Impurity10 Idebenone Impurity10. Uses: For analytical and research use. Molecular formula: C20H32O5. Mole weight: 352.47. Catalog: APB11279. Alfa Chemistry Analytical Products 2
Idebenone Impurity11 Idebenone Impurity11. Uses: For analytical and research use. Molecular formula: C18H28O4. Mole weight: 308.42. Catalog: APB11282. Alfa Chemistry Analytical Products 2
Idebenone Impurity12 Idebenone Impurity12. Uses: For analytical and research use. CAS No. 116460-82-3. Molecular formula: C18H28O4. Mole weight: 308.42. Catalog: APB116460823. Alfa Chemistry Analytical Products 2
Idebenone Impurity13 Idebenone Impurity13. Uses: For analytical and research use. Molecular formula: C19H30O6. Mole weight: 354.44. Catalog: APB11280. Alfa Chemistry Analytical Products 2
Idebenone Impurity14 Idebenone Impurity14. Uses: For analytical and research use. CAS No. 77712-29-9. Molecular formula: C19H32O4. Mole weight: 324.4. Catalog: APB77712299. Alfa Chemistry Analytical Products 4
Idebenone Impurity15 Idebenone Impurity15. Uses: For analytical and research use. CAS No. 634-85-5. Molecular formula: C6HCl3O2. Mole weight: 211.42. Catalog: APB634855. Alfa Chemistry Analytical Products 4
Idebenone Impurity16 Idebenone Impurity16. Uses: For analytical and research use. CAS No. 38969-08-3. Molecular formula: C8H6Br2O2. Mole weight: 293.94. Catalog: APB38969083. Alfa Chemistry Analytical Products 4
Idebenone Impurity17 Idebenone Impurity17. Uses: For analytical and research use. CAS No. 87405-27-4. Molecular formula: C8H6Br2O2. Mole weight: 293.94. Catalog: APB87405274. Alfa Chemistry Analytical Products 4
Idebenone Impurity18 Idebenone Impurity18. Uses: For analytical and research use. CAS No. 2435-54-3. Molecular formula: C6Br4O2. Mole weight: 432.68. Catalog: APB2435543. Alfa Chemistry Analytical Products 3
Idebenone Impurity2 Idebenone Impurity2. Uses: For analytical and research use. CAS No. 88543-34-4. Molecular formula: C18H28O5. Mole weight: 324.42. Catalog: APB88543344. Alfa Chemistry Analytical Products 4
Idebenone Impurity3 Idebenone Impurity3. Uses: For analytical and research use. CAS No. 88543-33-3. Molecular formula: C18H28O5. Mole weight: 324.42. Catalog: APB88543333. Alfa Chemistry Analytical Products 4
Idebenone Impurity4 Idebenone Impurity4. Uses: For analytical and research use. Molecular formula: C19H32O5. Mole weight: 340.46. Catalog: APB11278. Alfa Chemistry Analytical Products 2
Idebenone Impurity5 Idebenone Impurity5. Uses: For analytical and research use. Molecular formula: C19H31NO4. Mole weight: 337.46. Catalog: APB11275. Alfa Chemistry Analytical Products 2
Idebenone Impurity6 Idebenone Impurity6. Uses: For analytical and research use. Molecular formula: C17H26O5. Mole weight: 310.39. Catalog: APB11276. Alfa Chemistry Analytical Products 2
Idebenone Impurity7 Idebenone Impurity7. Uses: For analytical and research use. Molecular formula: C12H22O4. Mole weight: 230.3. Catalog: APB11277. Alfa Chemistry Analytical Products 2
Idebenone Impurity8 Idebenone Impurity8. Uses: For analytical and research use. CAS No. 104967-07-9. Molecular formula: C22H34O6. Mole weight: 294.51. Catalog: APB104967079. Alfa Chemistry Analytical Products 2
Idebenone Impurity9 Idebenone Impurity9. Uses: For analytical and research use. CAS No. 104966-92-9. Molecular formula: C21H32O6. Mole weight: 380.48. Catalog: APB104966929. Alfa Chemistry Analytical Products 2
Idebenone Sulfate-13C,d3 Potassium Salt Idebenone Sulfate-13C,d3 Potassium Salt. Group: Biochemicals. Alternative Names: 2,3-Dimethoxy-5-methyl-6-[10-(sulfooxy)decyl]-2,5-cyclohexadiene-1,4-dione13C,d3 Potassium Salt. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C1813CH26D3KO8S, Molecular Weight: 460.6. US Biological Life Sciences. USBiological 11
Worldwide
Idelalisib Idelalisib (CAL-101; GS-1101) is a highly selective and orally bioavailable p110δ inhibitor with an IC50 of 2.5 nM, showing 40- to 300-fold selectivity for p110δ over other PI3K class I enzymes. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CAL-101; GS-1101. CAS No. 870281-82-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13026. MedChemExpress MCE
Idelalisib Idelalisib is a kinase inhibitor. In combination with rituximab, it was used for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL). Uses: The treatment of chronic lymphocytic leukemia (cll). Alternative Names: Idelalisib; CAL101; CAL 101; CAL-101; GS1101; GS 1101; GS-1101, Idelalisib. Grades: > 95%. CAS No. 870281-82-6. Molecular formula: C22H18FN7O. Mole weight: 415.432. BOC Sciences 3
Idelalisib D5 Idelalisib D5, a version of Idelalisib marked with deuterium, is an orally bioavailable and highly selective inhibitor of p110δ. Category: Active pharmaceutical ingredients. Synonyms: CAL-101 D5, GS-1101 D5. CAS No. 1830330-31-8. Product ID: API1830330318. Molecular formula: C22H18FN7O. Mole weight: 420.45. Protheragen
IDF-11774 IDF-11774 is a novel hypoxia-inducible factor α (HIFα)-1 inhibitor with an IC50 of 3.65?μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1429054-28-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-111387. MedChemExpress MCE
IDH1 Inhibitor 2 IDH1 Inhibitor 2 (compound 13) is a potent wild-type IDH1 inhibitor that exerts its activity through covalent modification of His315 with an IC50 value of 110 nM. IDH1 Inhibitor 2 can dose-dependently reduce the intracellular reduced glutamine metabolic flux, thereby affecting cellular metabolic homeostasis. IDH1 Inhibitor 2 can be used to study the role of IDH1 in cellular metabolic regulation and cancer development[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2244895-42-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-128661. MedChemExpress MCE
IDH889 IDH889 is an orally available, brain penetrant, allosteric and mutant specific inhibitor of isocitrate dehydrogenase 1 (IDH1). IDH889 has potent selectivity for IDH1 R132* mutations, with IC50s of 0.02 μM, 0.072 μM and 1.38 μM for IDH1R132H, IDH1R132C and IDH1wt, respectively. IDH889 shows potent cellular inhibition of R-2-hydroxyglutarate (2-HG) production with an IC50 of 0.014 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1429179-07-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112289. MedChemExpress MCE
Idicalciferol impurity EDC-E Idicalciferol impurity EDC-E. Uses: For analytical and research use. Molecular formula: C30H50O5. Mole weight: 490.73. Catalog: APB11284. Alfa Chemistry Analytical Products 2
Idicalciferol impurity EDC-F Idicalciferol impurity EDC-F. Uses: For analytical and research use. Molecular formula: C30H50O5. Mole weight: 490.73. Catalog: APB11283. Alfa Chemistry Analytical Products 2
Idicalciferol impurity EDC-L Idicalciferol impurity EDC-L. Uses: For analytical and research use. CAS No. 158689-03-3. Molecular formula: C30H50O5. Mole weight: 490.73. Catalog: APB158689033. Alfa Chemistry Analytical Products 3
IDO1-IN-15 IDO1-IN-15 is an effective IDO1 inhibitor with IC50 of 127 nM. The potency of IDO1-IN-15 against IDO1 enzyme is comparable with Epacadostat in vitro. Category: Active pharmaceutical ingredients. CAS No. 2126853-17-4. Product ID: API2126853174. Molecular formula: C13H14BrFN6O3. Mole weight: 401.19. Protheragen
IDO-IN-7 IDO-IN-7 (NLG-919 analogue) is a a potent IDO1 inhibitor with an IC50 of 38 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NLG-919 analogue; GDC-0919 analogue. CAS No. 1402836-58-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13983. MedChemExpress MCE
IDOR-1117-2520 IDOR-1117-2520 is an orally active, potent, selective and reversible CCR6 antagonist. IDOR-1117-2520 antagonizes the CCL20-mediated calcium flow (IC50 = 63 nM) and inhibits β-arrestin recruitment to human CCR6 (IC50 = 30 nM) in cells expressing recombinant human CCR6. IDOR-1117-2520 is found to be a substrate of P-gp/MDR1. IDOR-1117-2520 can be used in the research of autoimmune diseases and skin inflammation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2737274-49-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-162495. MedChemExpress MCE
IDOR-4 IDOR-4 is a type IV CFTR corrector. IDOR-4 restores F508del-CFTR trafficking to the cell surface[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2839901-24-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-158002. MedChemExpress MCE
IDO/TDO-IN-1 IDO/TDO-IN-1 (compound 25) is a highly potent and orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor with IC50s of 9.7 and 47 nM, respectively [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2033173-01-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128355. MedChemExpress MCE
Idoxanthin Idoxanthin. Group: Biochemicals. Alternative Names: (3RS,3'RS,4'RS)-Trihydroxy-b,b-caroten-4-one. Grades: Highly Purified. CAS No. 25510-19-4. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C40H54O4. US Biological Life Sciences. USBiological 11
Worldwide
Idoxuridine Idoxuridine (5-Iodo-2-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC50 value of 4.3 μM[1]. Idoxuridine shows anti-orthopoxvirus activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5-Iodo-2-deoxyuridine; 5-IUdR; IdUrd. CAS No. 54-42-2. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-B0307. MedChemExpress MCE
IDP TEA salt IDP TEA salt is a pivotal constituent in the biomedical field, serving as a precursor for crucial molecules engaged in cellular processes. Its applied scope encompasses the synthesis of paramount compounds pertinent to studying viral invasions, immune disorders, and select cancerous conditions. Alternative Names: Inosine-5'-diphosphate, triethylammonium salt; Inosine 5'-(trihydrogen diphosphate), triethylammonium salt (1:x); Inosine 5'-(trihydrogen diphosphate), triethylammonium salt; 5'-IDP triethylammonium salt; Inosine 5-diphosphate triethylammonium salt; Inosine diphosphate triethylammonium salt. Grades: ≥95% by HPLC. Molecular formula: C10H14N4O11P2 (free acid). Mole weight: 428.18 (free acid). BOC Sciences 7
IDR-1 IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. CAS No. 940291-10-1. Molecular formula: C65H118N18O15. Mole weight: 242.31. BOC Sciences 9
IDRA 21 IDRA 21. Group: Biochemicals. Grades: Purified. CAS No. 22503-72-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 11
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IDT307 IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1141-41-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129096. MedChemExpress MCE
iduronate-2-sulfatase Iduronate 2-sulfatase (IDS) is a sulfatase enzyme associated with Hunter syndrome. Group: Enzymes. Synonyms: chondroitinsulfatase; idurono-2-sulfatase; iduronide-2-sulfate sulfatase; L-iduronosulfatase; L-idurono sulfate sulfatase; iduronate sulfatase; sulfo-L-iduronate sulfatase; L-iduronate 2-sulfate sulfatase; sulfoiduronate sulfohydrolase; 2-sulfo-L-iduronate 2-sulfatase; iduronate-2-sulfate sulfatase; iduronate sulfate sulfatase. Enzyme Commission Number: EC 3.1.6.13. CAS No. 50936-59-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3746; iduronate-2-sulfatase; EC 3.1.6.13; 50936-59-9; chondroitinsulfatase; idurono-2-sulfatase; iduronide-2-sulfate sulfatase; L-iduronosulfatase; L-idurono sulfate sulfatase; iduronate sulfatase; sulfo-L-iduronate sulfatase; L-iduronate 2-sulfate sulfatase; sulfoiduronate sulfohydrolase; 2-sulfo-L-iduronate 2-sulfatase; iduronate-2-sulfate sulfatase; iduronate sulfate sulfatase. Cat No: EXWM-3746. Creative Enzymes
Iduronic acid L-Iduronic acid is a crucial component in the biomedical industry used for various purposes. It is commonly employed in the synthesis of dermatan sulfate, a polysaccharide found in connective tissues. Additionally, L-Iduronic acid is utilized in the production of heparan sulfate, a glycosaminoglycan involved in different biological processes. Alternative Names: d-iduronic acid; 3402-98-0; Iduronic acid, D-; (2S,3R,4R,5S)-2,3,4,5-tetrahydroxy-6-oxohexanoic acid; F5HD8XQ3DP; 8DWF4HK64B; 21675-53-6; UNII-F5HD8XQ3DP; UNII-8DWF4HK64B; IDURONIC ACID, DL-; SCHEMBL147158; DTXSID90187632; IAJILQKETJEXLJ-LECHCGJUSA-N; Q418846; W-202387. Grades: ≥95%. CAS No. 3402-98-0. Molecular formula: C6H10O7. Mole weight: 194.14. BOC Sciences 7

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