A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Ifenprodil is an NMDA receptor antagonist and acts at the polyamine site. It is also an α2 adrenergic receptor ligand. It is selective for σ2 ligand over σ1 sites. It is used as a neuroprotective agent and peripheral vasodilator. Uses: Excitatory amino acid antagonists. Synonyms: 4-[2-(4-Benzylpiperidin-1-yl)-1-hydroxypropyl]phenol; (1R*,2S*)-erythro-2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol; α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidineethanol; 1-Methyl-2-hydroxy-2-(4-hydroxyphenyl)ethyl-1-(4-benzylpiperidine); 2-(4-Benzylpiperidino)-1-(1-hydroxyphenyl)-1-propanol; RC 61-91. Grade: ≥99% by HPLC. CAS No. 23210-56-2. Molecular formula: C21H27NO2. Mole weight: 325.44.
Ifenprodil
Ifenprodil is a NMDA receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 23210-56-2. Pack Sizes: 5mg, 10mg. Molecular Formula: C21H27NO2, Molecular Weight: 325.44. US Biological Life Sciences.
Worldwide
Ifenprodil
Ifenprodil (NP-120), a cerebral vasodilator, is a noncompetitive NMDA receptor antagonist. Ifenprodil exerts high affinity at NR1A/NR2B receptors (IC50=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC50=146 μM)[1]. Ifenprodil is an α1 adrenergic receptor antagonist. Ifenprodil inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil has reliable inhibitory effects against A/H1N1 strains (EC50 of 6.6 μM). Ifenprodil has neuroprotective, anticonvulsant and antinociceptive effects. Ifenprodil can be used for the study of cerebrovascular diseases and peripheral arterial obliterative disease[2][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NP-120; RC-61-91. CAS No. 23210-56-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12882.
Ifenprodil hemitartrate
Ifenprodil hemitartrate. Group: Biochemicals. Grades: Purified. CAS No. 23210-56-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ifenprodil Hemitartrate.
Vasodilator (cerebral and peripheral). Group: Biochemicals. Alternative Names: α-(4-Hydroxyphenyl)- β-methyl-4-(phenylmethyl)-1-piperidineethanol (2R,3R)-2,3-Dihydroxybutanedioate. Grades: Highly Purified. CAS No. 23210-58-4. Pack Sizes: 10mg. US Biological Life Sciences.
A partial non-competitive antagonist highly selective for GluN1/N2B subtype nMDA receptors (IC50 = 0.15uM, maximal inhibition 90%) over other subtypes (IC50 = 39, 29, 76uM for GluN1/N2A, GluN1/N2C and GluN1/N2D subtype receptors, respectively). Frequently used in studies of various brain functions and disorders involving neural transmissions mediated by GluN1/N2B subtype nMDA receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 23210-58-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Ifenprodil Tartrate
Ifenprodil is an atypical noncompetitive antagonist at the NMDA receptor, it interacts with high affinity at a homogeneous population of NMDA receptors in neonatal rat forebrain with IC50 of 0.3 μM. Uses: Adrenergic alpha-antagonists. Synonyms: Ifenprodil (tartrate). Grade: >98%. CAS No. 23210-58-4. Molecular formula: 2(C21H27NO2).C4H6O6. Mole weight: 800.98.
Iferanserin
Iferanserin (S-MPEC) is a selective 5-HT receptor (serotonin receptor) antagonist with an affinity for 5-HT2A receptor. Iferanserin has the potential for internal hemorrhoid disease treatment[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S-MPEC. CAS No. 58754-46-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118557.
Ifetroban
Ifetroban is a selective Prostaglandin receptor and Thromboxane A2 receptor antagonist under the development of Bristol-Myers Squibb. Phase II clinical trials for the treatment of Asthma, Hepatorenal syndrome, Portal hypertension and Systemic scleroderma is on-going. Uses: Asthma; hepatorenal syndrome; portal hypertension; systemic scleroderma. Synonyms: Ifetroban; BMS 180291-02; BMS-180291; BMS180291; CHEMBL283100; BMS-180291; SCHEMBL9589119; 3-[2-[[3-[4-(pentylcarbamoyl)-1,3-oxazol-2-yl]-7-oxabicyclo[2.2.1]heptan-2-yl]methyl]phenyl]propanoic acid. Grade: 98%. CAS No. 143443-90-7. Molecular formula: C25H32N2O5. Mole weight: 440.54.
Ifidancitinib
Ifidancitinib is a potent and selective JAK kinases 1/3 inhibitor for the research of allergies, asthma and autoimmune diseases. Synonyms: ATI-50002; ATI-502; 2(3H)-Benzoxazolone, 5-((2-((4-fluoro-3-methoxy-5-methylphenyl)amino)-5-methyl-4-pyrimidinyl)amino)-; 5-((2-((4-Fluoro-3-methoxy-5-methylphenyl)amino)-5-methyl-4-pyrimidinyl)amino)-2(3H)-benzoxazolone; 5-((2-(4-Fluoro-3-methoxy-5-methylphenylamino)-5-methylpyrimidin-4-yl)amino)benzo(d)oxazol-2(3H)-one. CAS No. 1236667-40-5. Molecular formula: C20H18FN5O3. Mole weight: 395.39.
Ifidancitinib
Ifidancitinib (ATI-50002) is an orally available, potent and selective inhibitor of JAK kinase 1/3 that disrupts γc cytokine signaling. Ifidancitinib is used in the research of allergy, asthma, and autoimmune diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ATI-50002; ATI-502. CAS No. 1236667-40-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109178.
Ifinatamab
Ifinatamab is monoclonal immunoglobulin G1-kappa with anti-human B7 homolog 3 protein (Human B7-H3). Ifinatamab is a glycoforme α immunomodulateur[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DS-7300a Antibody; MABX-9001A Antibody. CAS No. 2484870-90-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99367.
Ifinatamab deruxtecan
Ifinatamab deruxtecan (DS-7300a) is a B7-H3-targeting Antibody-drug conjugate (ADC), which is composed of a humanized anti-B7-H3 monoclonal antibody, an enzymatically cleavable peptide-based linker, and Exatecan derivative (DXd) (HY-13631D). Ifinatamab deruxtecan is a DNA Topoisomerase I inhibitor. Ifinatamab deruxtecan induces Apoptosis. DS-7300a exerts potent antitumor activities against B7-H3-expressing tumors. against rhabdomyosarcoma, endometrial adenocarcinoma and lung adenocarcinoma. Ifinatamab deruxtecan does not exert direct immunomodulatory effects[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DS-7300a; MABX-9001a; I-DXd. CAS No. 2484870-92-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P3371.
IFNα
Recombinant human IFNα; A type I interferon consisting of 165 amino acid residues with lysine in position 23. It is used extensively as an antiviral or antineoplastic agent. An oral form is being developed by Amarillo Biosciences.
IFN alpha-IFNAR-IN-1
IFN alpha-IFNAR-IN-1 is a nonpeptidic, low-molecular-weight inhibitor. It inhibits MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM). It exerts immunosuppressive activity by the direct interaction with IFN-α. Uses: Ifn alpha-ifnar-in-1 inhibits mva-induced ifn-α responses by bm-pdcs. it exerts immunosuppressive activity by the direct interaction with ifn-α. Synonyms: IFN-alpha; IFN alpha; IFNAR-IN-1; IFNAR IN 1; IFNARIN1; IFNAR inhibitor 1; IFNAR-inhibitor-1; IFN-alpha and IFNAR interaction inhibitor. Grade: >98%. CAS No. 844882-93-5. Molecular formula: C18H17NS. Mole weight: 279.40.
IFN alpha-IFNAR-IN-1 hydrochloride
IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptide, low-molecular-weight inhibitor. It inhibits modified Vaccinia virus ankara (MVA)-induced IFN-α responses in murine bone-marrow-derived, Flt3-L-differentiated pDC cultures (BM-pDCs) (IC50=2-8 μM). Synonyms: IFN alpha-IFNAR-IN-1 (hydrochloride); IFN-α-IFNAR-IN-1 (hydrochloride). Grade: 98%. CAS No. 2070014-98-9. Molecular formula: C18H18ClNS. Mole weight: 315.86.
IFN alpha-IFNAR-IN-1 hydrochloride
IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits modified Vaccinia virus ankara (MVA)-induced IFN-α responses in murine bone-marrow-derived, Flt3- L-differentiated pDC cultures (BM-pDCs) (IC50=2-8 μM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2070014-98-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12836A.
IFNα-IN-1
IFNα-IN-1 (AJ2-18) is a IFNα inhibitor that inhibits IFN-α production. IFNα-IN-1 can be used for research of inflammation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2700322-66-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-170331.
IFN-α Receptor Recognition Peptide 1
IFN-α Receptor Recognition Peptide 1 is an IFN-α peptide associated with receptor interaction. Synonyms: IRRP1; IFN-alpha Receptor Recognition Peptide 1; H-Cys-Leu-Lys-Asp-Arg-His-Asp-OH; L-cysteinyl-L-leucyl-L-lysyl-L-alpha-aspartyl-L-arginyl-L-histidyl-L-aspartic acid. Grade: ≥95%. CAS No. 153840-64-3. Molecular formula: C35H59N13O12S. Mole weight: 885.99.
IFN-γ Antagonist
IFN-γ Antagonist, derived from the ligand binding site of human γ-interferon (IFN-γ) receptor, is an antagonist of human IFN-γ, and inhibits human IFN-γ-induced expression of HLR/DR antigen on Colo 205 cells with an IC50 of about 35 μM. Synonyms: (Tyr121,Cys(Acm)122)-IFN-γ Receptor (120-141) (human); L-Isoleucine, L-alanyl-L-tyrosyl-S-[(acetylamino)methyl]-L-cysteinyl-L-arginyl-L-α-aspartylglycyl-L-lysyl-L-isoleucylglycyl-L-prolyl-L-prolyl-L-lysyl-L-leucyl-L-α-aspartyl-L-isoleucyl-L-arginyl-L-lysyl-L-α-glutamyl-L-α-glutamyl-L-lysyl-L-glutaminyl-; L-alanyl-L-tyrosyl-S-acetamidomethyl-L-cysteinyl-L-arginyl-L-alpha-aspartyl-glycyl-L-lysyl-L-isoleucyl-glycyl-L-prolyl-L-prolyl-L-lysyl-L-leucyl-L-alpha-aspartyl-L-isoleucyl-L-arginyl-L-lysyl-L-alpha-glutamyl-L-alpha-glutamyl-L-lysyl-L-glutaminyl-L-isoleucine; H-Ala-Tyr-Cys(Acm)-Arg-Asp-Gly-Lys-Ile-Gly-Pro-Pro-Lys-Leu-Asp-Ile-Arg-Lys-Glu-Glu-Lys-Gln-Ile-OH. Grade: ≥95%. CAS No. 158040-83-6. Molecular formula: C115H194N34O34S. Mole weight: 2629.04.
IFN-γ Antagonist 1
IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) is an interferon-γ (IFN-γ) antagonist. IFN-γ Antagonist 1 inhibits IFN-γ-induced HLR/DR antigen expression in cells. IFN-γ Antagonist 1 can be used in researches of diseases with abnormal immune regulation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 158040-83-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P4717.
Ifosfamide
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C7H15Cl2N2O2P. CAS No. 3778-73-2. Prepack ID 43331190-1g. Molecular Weight 261.09. See USA prepack pricing.
Ifosfamide
Ifosfamide is a nitrogen mustard alkylating agent used in the treatment of cancer. Uses: Antineoplastic agents, alkylating. Synonyms: 2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide; 2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide; (2-Chloro-ethyl)-[3-(2-chloro-ethyl)-2-oxo-2λ*5*-[1,3,2]oxazaphosphinan-2-yl]-amine; (±)-Ifosfamide; 3-(2-Chloroethyl)-2-(2-chloroethylamino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide; A 4942; Asta Z 4942; Cyfos; Holoxan; Holoxan 1000; Ifex; Ifomide; Ifosfamid; Ifosfomide; Ifosphamide; Iphosphamide; Isoendoxan; Isofosfamide; Isophosphamide; Mitoxana; MJF 9325; Naxamide; NSC 109724; Z 4942. Grade: >98%. CAS No. 3778-73-2. Molecular formula: C7H15Cl2N2O2P. Mole weight: 261.09.
Ifosfamide
Ifosfamide is a CNS-penetrant alkylating chemotherapeutic agent with activity against a wide range of tumors. Uses: Scientific research. Category: Signaling pathways. CAS No. 3778-73-2. Pack Sizes: 10 mM * 1 mL in DMSO; 200 mg; 500 mg. Product ID: HY-17419.
Ifosfamide-d4
A cytostatic agent, related structurally to cyclophosphamide. Group: Biochemicals. Alternative Names: N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-Oxide-d4. Grades: Highly Purified. CAS No. 1189701-13-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ifosfamide-[d4]
Ifosfamide-[d4] is the labelled analogue of Ifosfamide. Ifosfamide is a chemotherapy medication used to treat a number of types of cancer. Synonyms: Ifosfamide D4; N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-Oxide-d4. Grade: 95% by HPLC; 98% atom D. CAS No. 1189701-13-0. Molecular formula: C7H11D4Cl2N2O2P. Mole weight: 265.11.
Ifosfamide EP impurity A
Ifosfamide EP impurity A. Uses: For analytical and research use. CAS No. 22608-58-8. Molecular formula: C5H13ClNO4P. Mole weight: 217.59. Catalog: APB22608588.
Ifosfamide EP impurity B
Ifosfamide EP impurity B. Uses: For analytical and research use. CAS No. 241482-18-8. Molecular formula: C10H24Cl2N2O7P2. Mole weight: 417.16. Catalog: APB241482188.
Ifosfamide EP impurity C HCl
Ifosfamide EP impurity C HCl. Uses: For analytical and research use. CAS No. 870-24-6. Molecular formula: C2H7Cl2N. Mole weight: 115.99. Catalog: APB870246.
Ifosfamide EP impurity E
Ifosfamide EP impurity E. Uses: For analytical and research use. CAS No. 42453-19-0. Molecular formula: C5H11Cl2N. Mole weight: 156.05. Catalog: APB42453190.
Ifosfamide EP impurity F
Ifosfamide EP impurity F. Uses: For analytical and research use. CAS No. 81485-04-3. Molecular formula: C5H10Cl2NO2P. Mole weight: 218.01. Catalog: APB81485043.
Ifosfamide impurity 1
Ifosfamide impurity 1. Uses: For analytical and research use. CAS No. 119670-13-2. Molecular formula: C7H13Cl2N2O3P. Mole weight: 275.07. Catalog: APB119670132.
Ifosfamide impurity 2. Uses: For analytical and research use. Molecular formula: C8H17Cl2N2O2P. Mole weight: 275.11. Catalog: APB10581.
Ifosfamide impurity 3
Ifosfamide impurity 3. Uses: For analytical and research use. CAS No. 2649320-48-7. Molecular formula: C8H17Cl2N2O2P. Mole weight: 275.11. Catalog: APB2649320487.
Ifosfamide Impurity A
Ifosfamide Impurity A. Synonyms: 3-[(2-chloroethyl)amino]propyl dihydrogen phosphate. Grade: > 95%. CAS No. 22608-58-8. Molecular formula: C5H13ClNO4P. Mole weight: 217.59.
Ifosfamide Impurity B
Ifosfamide Impurity B. Synonyms: Bis[3-[(2-chloroethyl)amino]propyl] dihydrogen diphosphate. Grade: > 95%. CAS No. 241482-18-8. Molecular formula: C10H24Cl2N2O7P2. Mole weight: 417.17.
Ifosfamide Impurity E
Ifosfamide Impurity E. Synonyms: 3-chloro-N-(2-chloroethyl)propan-1-amine. Grade: > 95%. CAS No. 42453-19-0. Molecular formula: C5H11Cl2N. Mole weight: 156.06.
Ifosfamide Impurity F
Ifosfamide Impurity F. Synonyms: Ifosfamide Impurity F; 81485-04-3. Grade: > 95%. CAS No. 81485-04-3. Molecular formula: C5H10Cl2NO2P. Mole weight: 218.02.
iFSP1
iFSP1 is a potent, selective and glutathione-independent inhibitor of ferroptosis suppressor protein 1 (FSP1/AIFM2) with EC50 of 103 nM. iFSP1 sensitizes cancer cell lines from different origins to RSL3-induced ferroptosis Dose-dependent toxicity of RSL3 in a panel of human cancer cell lines from different origins treated with or without iFSP1 and Lip-1. Synonyms: 1-Amino-3-p-tolyl-benzo[4,5]imidazo[1,2-a]pyridine-2,4-dicarbonitrile. CAS No. 150651-39-1. Molecular formula: C20H13N5. Mole weight: 323.35.
iFSP1
iFSP1 is a potent, selective and glutathione-independent inhibitor of ferroptosis suppressor protein 1 (FSP1) (AIFM2) with an EC50 of 103 nM. iFSP1 selectively induces ferroptosis in GPX4-knockout cells which overexpressed FSP1. iFSP1 is able to sensitize a variety of human cancer cell lines to the ferroptosis inducer, such as (1S,3R)-RSL3 (HY-100218A)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 150651-39-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136057.
IG-105 is a potent microtubule inhibitor with potential anticancer activity. IG-105 inhibits microtubule assembly by binding at colchicine pocket. IG-105 shows a potent anticancer activity in vitro and in vivo and has good safety in mice. IG-105 showed a potent activity against human leukemia and solid tumors in breast, liver, prostate, lung, skin, colon, and pancreas with IC(50) values between 0.012 and 0.298 mumol/L. It was also active in drug-resistant tumor cells and not a P-glycoprotein substrate. It inhibited microtubule assembly followed by M-phase arrest, Bcl-2 inactivation, and then apoptosis through caspase pathways. Synonyms: IG105; IG 105. Grade: 98%. CAS No. 905978-63-4. Molecular formula: C20H19N3O4S. Mole weight: 397.45.
Iganidipine
Iganidipine is a calcium channel blocker and optic nerve circulation vasodilator. Synonyms: 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-2,2-dimethyl-3-[4-(2-propenyl)-1-piperazinyl]propyl Methyl Ester 3,5-Pyridinedicarboxylic Acid; (±)-3-(4-Allyl-1-piperazinyl)-2,2-dimethylpropylmethyl-1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2,2-dimethyl-3-[4-(2-propen-1-yl)-1-piperazinyl]propyl methyl ester. Grade: 95%. CAS No. 119687-33-1. Molecular formula: C28H38N4O6. Mole weight: 526.62.
IgA-specific metalloendopeptidase
A 190 kDa enzyme found in several pathogenic species of Streptococcus such as sanguis and pneumoniae. Type example of peptidase family M26. There is also an IgA-specific prolyl endopeptidase of the serine-type (see EC 3.4.21.72, IgA-specific serine endopeptidase). Group: Enzymes. Synonyms: immunoglobulin A1 proteinase; IgA protease; IgA1-specific proteinase; IgA1 protease; IgA1 proteinase. Enzyme Commission Number: EC 3.4.24.13. CAS No. 72231-73-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4294; IgA-specific metalloendopeptidase; EC 3.4.24.13; 72231-73-3; immunoglobulin A1 proteinase; IgA protease; IgA1-specific proteinase; IgA1 protease; IgA1 proteinase. Cat No: EXWM-4294.
IgA-specific serine endopeptidase
Species variants differing slightly in specificity are secreted by Gram-negative bacteria Neisseria gonorrhoeae and Haemophilus influenzae. Type example of peptidase family S6. Some other bacterial endopeptidases with similar specificity are of metallo- type (see EC 3.4.24.13, IgA-specific metalloendopeptidase). Group: Enzymes. Synonyms: IgA protease; IgA proteinase; IgA-specific proteinase; immunoglobulin A protease; immunoglobulin A proteinase. Enzyme Commission Number: EC 3.4.21.72. CAS No. 55127-02-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4164; IgA-specific serine endopeptidase; EC 3.4.21.72; 55127-02-1; IgA protease; IgA proteinase; IgA-specific proteinase; immunoglobulin A protease; immunoglobulin A proteinase. Cat No: EXWM-4164.
Igepal CO-520
Igepal CO-520. Group: Biochemicals. Alternative Names: Poly(oxy-1,2-ethanediyl),a-(nonylphenyl)-w-hydroxy-, Branched Polymer; α-(Nonylphenyl)-ω-hydroxy-poly(oxy-1,2-ethanediyl) Branched Polymer. Grades: Highly Purified. CAS No. 68412-54-4. Pack Sizes: 1g, 250g, 500g. US Biological Life Sciences.
Worldwide
IGF-1 LR3
IGF-1 LR3 is a lengthened analogue of human insulin-like growth factor 1 (IGF-1). Synonyms: Long R3-IGF-1; IGF-1 Long R3; Long arginine 3-IGF-1. Grade: 95%. CAS No. 946870-92-4. Molecular formula: C400H625N111O115S9. Mole weight: 9117.6.
IGF-1R inhibitor-2
IGF-1R inhibitor-2 is an inhibitor of insulin-like growth factor-1 receptor (IGF-1R). Downregulation of IGF-1R can reverse the transformed phenotype of tumor cells and potentially render them susceptible to apoptosis. Synonyms: 2-fluoro-6-((2-((6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)benzamide. CAS No. 1116236-15-7. Molecular formula: C24H24FN7O2. Mole weight: 461.49.
IGF1Rtide
IGF1Rtide can be used as a RET kinase substrate for RET kinase assays[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 172615-51-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10044.
IGF2BP1-IN-1
IGF2BP1-IN-1 (Compound A11) is a IGF2BP1 inhibitor and inhibits downstream signaling. IGF2BP1-IN-1 binds to IGF2BP1 protein with a KD value of 2.88 nM. IGF2BP1-IN-1 inhibits cancer cells proliferation (IC50: 9 nM for A549 cell, 34 nM for HCT116). IGF2BP1-IN-1 induces cancer cell apoptosis. GF2BP1-IN-1 inhibits tumor growth in A549 xenograft mouse model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3029447-08-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156110.
IGF-I 24-41
IGF-I 24-41 is a 24-41 amino acid fragment of insulin-like growth factor I(IGF-I). IGF-I has anabolic, antioxidant, anti-inflammatory and cell-protective properties. Synonyms: Insulin-like Growth Factor I (24-41); H-Tyr-Phe-Asn-Lys-Pro-Thr-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-OH; L-tyrosyl-L-phenylalanyl-L-asparagyl-L-lysyl-L-prolyl-L-threonyl-glycyl-L-tyrosyl-glycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-L-threonine. Grade: ≥95%. CAS No. 135861-49-3. Molecular formula: C88H133N27O28. Mole weight: 2017.16.
IGF-I (24-41) TFA
IGF-I (24-41) TFA is a 24-41 amino acid fragment of insulin-like growth factor I(IGF-I). IGF-I has anabolic, antioxidant, anti-inflammatory and cell-protective properties. Synonyms: Insulin-like Growth Factor I (24-41) (TFA); IGF-I (24-41) Trifluoroacetate; H-Tyr-Phe-Asn-Lys-Pro-Thr-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-OH.TFA; L-tyrosyl-L-phenylalanyl-L-asparagyl-L-lysyl-L-prolyl-L-threonyl-glycyl-L-tyrosyl-glycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-L-threonine Trifluoroacetate. Grade: >98%. Molecular formula: C88H133N27O28.C2HF3O2. Mole weight: 2131.18.
IGF-I 30-41
IGF-I 30-41 is a 30-41 amino acid fragment of insulin-like growth factor I(IGF-I). IGF-I has anabolic, antioxidant, anti-inflammatory and cell-protective properties. Synonyms: Insulin-like Growth Factor I (30-41); H-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-OH; glycyl-L-tyrosyl-glycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-L-threonine. Grade: ≥95%. CAS No. 82177-09-1. Molecular formula: C51H83N19O19. Mole weight: 1266.32.
IGF-I 30-41 acetate
IGF-I 30-41 acetate is a 30-41 amino acid fragment of insulin-like growth factor I(IGF-I). IGF-I has anabolic, antioxidant, anti-inflammatory and cell-protective properties. Synonyms: Insulin-like Growth Factor I (30-41) acetate; H-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-OH.CH3CO2H; glycyl-L-tyrosyl-glycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-L-threonine acetic acid. Grade: ≥95%. Molecular formula: C53H87N19O21. Mole weight: 1326.39.
IGF-I (30-41) TFA
IGF-I (30-41) TFA is a 30-41 amino acid fragment of insulin-like growth factor I(IGF-I). IGF-I has anabolic, antioxidant, anti-inflammatory and cell-protective properties. Synonyms: Insulin-like Growth Factor I (30-41) (TFA); IGF-I (30-41) Trifluoroacetate; H-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-OH.TFA; glycyl-L-tyrosyl-glycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-L-threonine trifluoroacetate. Grade: >98%. Molecular formula: C51H83N19O19.C2HF3O2. Mole weight: 1380.36.
IGF-I Analog
The IGF-I peptide analog was able to inhibit the autophosphorylation of the IGF-I receptor by IGF-I as well as the growth of several different cell types, including prostate carcinoma cells and SV40-transformed cells. Synonyms: JB-1 peptide; Cys-Tyr-Ala-Ala-Pro-Leu-Lys-Pro-Ala-Lys-Ser-Cys disulfide. Grade: 95%. CAS No. 147819-32-7. Molecular formula: C55H88N14O15S2. Mole weight: 1249.5.
iGOT1-01 is a potent aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1; GOT1) inhibitor. iGOT1-01 has IC50s of 85 μM and 11.3 μM in MDH coupled GOT1 enzymatic assay and GOT1/GLOX/HRP assay, respectively. iGOT1-01 has anti-cancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 882256-55-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124825.
iGOT1-01
iGOT1-01 is a potent aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1/GOT1) inhibitor with anticancer activity. Synonyms: 1-Piperazinecarboxamide, 4-(1H-indol-4-yl)-N-phenyl. Grade: >98%. CAS No. 882256-55-5. Molecular formula: C19H20N4O. Mole weight: 320.39.
Igovomab
Igovomab is a mouse monoclonal antibody used as a diagnostic imaging agent for varian cancer research. Synonyms: Indimacis 125; Immunoglobulin G1, anti-(human CA 125 (carbohydrate antigen)) F(ab')2 fragment (mouse monoclonal OC125F(AB')2 γ1-chain), disulfide with mouse monoclonal OC125F(AB')2 light chain, dimer. Grade: 95%. CAS No. 171656-50-1.
iGP-1
iGP-1 is a cell-permeable, selective mixed inhibitor of mitochondrial sn-glycerol-3-phosphate dehydrogenase (mGPDH), with IC50s of 6.3 μM and 13.6 μM for rat mGPDH activity and H2O2 production, respectively. iGP-1 specifically blocks the mitochondrial component of the glycerophosphate shuttle without affecting cytosolic GPDH. iGP-1 not only inhibits cell proliferation and glutaminolysis, and enhances glycolysis, but also significantly alters key cellular physiological processes such as apoptosis, ROS production, HIF-1α stability and mitochondrial membrane potential. iGP-1 remains active in neutrophil cultures under both normoxic and hypoxic conditions, and serves as an ideal probe for glycerol-3-phosphate metabolic mechanisms. iGP-1 has been applied to studies on prostate cancer and related metabolic pathways[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 27031-00-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121970.
IGRP(206-214)
IGRP(206-214) is a biological active peptide. IGRP(206-214) corresponds to residues 206-214 of murine islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP). IGRP(206-214) is T cells specific for proinsulin and IGRP induces diabetes in non-obese diabetic (NOD) mice[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 849069-99-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5489.
IGRP(206-214)
IGRP(206-214) is the 206-214 amino acid residue of murine islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP). IGRP is a major autoantigen for autoimmune type 1 diabetes (T1D) in the NOD mouse model. Synonyms: IGRP Catalytic Subunit-related Protein (206-214); H-Val-Tyr-Leu-Lys-Thr-Asn-Val-Phe-Leu-OH. CAS No. 849069-99-4. Molecular formula: C54H85N11O13. Mole weight: 1096.3.
IGS-1.76
IGS-1.76 efficiently inhibits the human NCS-1/Ric8a complex. IGS-1.76 shows a significantly increased affinity for hNCS-1 and is able to modulate the hNCS-1/Ric8a interaction efficiently[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 313480-47-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122579.
IGS-1.76
IGS-1.76 is an inhibitor of the protein-protein interactions (PPI) that acts as a potential drug candidate for Fragile X syndrome pharmacotherapy. Synonyms: N-(benzo[d]thiazol-2-yl)-3,3-diphenylpropanamide. Grade: 98% by HPLC. CAS No. 313480-47-6. Molecular formula: C22H18N2OS. Mole weight: 358.5.
IGUANA-1
IGUANA-1 is a potent and selective ALDH1B1 inhibitor. IGUANA-1 shows no significant mitochondrial toxicity. IGUANA-1 has antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2756014-25-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148466.
Iguratimod
Iguratimod is a selective inhibitor of cyclo-oxygenase-2 (COX-2), and inhibits the production of interleukin-1 (IL-1), IL-6, IL-8 and tumour necrosis factor. Uses: Anti-inflammation agent. Synonyms: T 614; T-614; T614; N-(7-(Methylsulfonamido)-4-oxo-6-phenoxy-4H-chromen-3-yl)formamide; Careram; Kolbet; UNII-4IHY34Y2NV. Grade: 0.98. CAS No. 123663-49-0. Molecular formula: C17H14N2O6S. Mole weight: 374.367.
Iguratimod
Iguratimod. Group: Biochemicals. Alternative Names: N-[3-(Formylamino)-4-oxo-6-phenoxy-4H-1-benzopyran-7-yl]-methanesulfonamide; 3-Formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one; Careram; Kolbet; N-[3-(Formylamino)-4-oxo-6-phenoxy-4H-chromen-7-yl]methanesulfonamide; T 614; T 614 (antiinflammatory). Grades: Highly Purified. CAS No. 123663-49-0. Pack Sizes: 10mg. Molecular Formula: C17H14N2O6S, Molecular Weight: 374.37. US Biological Life Sciences.
Worldwide
Iguratimod Impurity 1
Iguratimod Impurity 1. Uses: For analytical and research use. CAS No. 2375563-22-5. Molecular formula: C15H17NO6S2. Mole weight: 371.42. Catalog: APB2375563225.