American Chemical Suppliers

A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.

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Product
U0124 U0124. Group: Biochemicals. Grades: Purified. CAS No. 108923-79-1. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 5
Worldwide
U0124 U0124, an inactive U0126 analog, has no effect on c-Fos and c-Jun protein or mRNA levels. U0126 is a MEK inhibitor. U0124 does not inhibit MEK at concentrations up to 100 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 108923-79-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107621. MedChemExpress MCE
U0126 U0126 is a potent, non-ATP competitive and selective MEK1 and MEK2 inhibitor, with IC50s of 72 nM and 58 nM, respectively. U0126 is an autophagy and mitophagy inhibitor[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 109511-58-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12031A. MedChemExpress MCE
U0126-EtOH U0126-EtOH Inhibitor. Uses: Scientific use. Product Category: T6223. CAS No. 1173097-76-1. TARGETMOL CHEMICALS
U0126-EtOH U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM in cell-free assays, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD98059. U0126 inhibits autophagy and mitophagy with antiviral activity. Group: Inhibitors. CAS No. 1173097-76-1. Pack Sizes: 25mg. Product ID: S1102. Formula: C18H16N6S2.C2H6O. Smiles: CCO.C1=CC=C(C(=C1)N)SC(=C(C#N)C(=C(N)SC2=CC=CC=C2N)C#N)N. Storage Conditions: 2 years -80 in solvent. Selleck Chemicals
United States; Europe
U0126-EtOH U0126 (U0126-EtOH) is a potent, non-ATP competitive and selective MEK1 and MEK2 inhibitor, with IC50s of 72 nM and 58 nM, respectively. U0126 is an autophagy and mitophagy inhibitor[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1173097-76-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg; 25 mg; 50 mg; 100 mg; 200 mg; 250 mg; 500 mg. Product ID: HY-12031. MedChemExpress MCE
U 104 U 104. Group: Biochemicals. Grades: Purified. CAS No. 178606-66-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
U-104 U-104 (SLC-0111) is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki values of 45.1 nM and 4.5 nM, respectively. U-104 shows a significant delay in tumor growth in mice model[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SLC-0111. CAS No. 178606-66-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-13513. MedChemExpress MCE
U18666A U18666A, an intra-cellular cholesterol transport inhibitor, inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3039-71-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107433. MedChemExpress MCE
U 18666A U 18666A. Group: Biochemicals. Grades: Purified. CAS No. 3039-71-2. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 5
Worldwide
U1 Polyethylene Packaging Profile With our U1 polyethylene packaging profiles, you can rest assured that your valuables are protected from damage during transport from one location to another. You can easily slide these onto a products edge in the use of items such as glass, windows, frames, or other items with slim profiles, or you can also them inside of a package to create a buffer to absorb vibrations and impacts. Alfa Chemistry Materials 6
U-20904 U-20904 is an antibiotic produced by Actinomycetes. It exhibits activity against Blastomycetes dermatitis and KB cells. Synonyms: Antibiotic U-20904. CAS No. 10567-30-3. Molecular formula: C4H6N2O2. Mole weight: 114.1. BOC Sciences 12
U2 Polyethylene Packaging Profile With our U2 polyethylene packaging profiles, rest assured that every item will be protected from scratches, scrapes, or other damage associated with fragile items. With their affordable nature and overall performance, these U2 polyethylene packaging profiles are the best solution for protecting valuable items at a great cost. Alfa Chemistry Materials 6
U3 Polyethylene Packaging Profile Offering valuable protection for glass, appliances, furniture, windows, and even used in garage doors, our polyethylene packaging profiles have a plethora of uses to protect your valuables. Simply purchase the channel you need in any size, and you will be able to adequately protect your belongings during a move. Alfa Chemistry Materials 6
U 46619 U 46619. Group: Biochemicals. Grades: Purified. CAS No. 56985-40-1. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 5
Worldwide
U-46619 U-46619 (9,11-Methanoepoxy PGH2) is a stable analogue of Thromboxane A2 (HY-113350) (TXA2) and acts as a potent TXA2 (TP) agonist. U-46619 also is a RhoA agonist. U-46619 stimulates the activation of RhoA through TXA2 receptor activation[1][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 9,11-Methanoepoxy PGH2. CAS No. 56985-40-1. Pack Sizes: 1 mg (28.5 mM * 100 μL in Methyl acetate); 5 mg (28.5 mM * 500 μL in Methyl acetate); 10 mg (28.5 mM * 1 mL in Methyl acetate). Product ID: HY-108566. MedChemExpress MCE
U-56407 U-56407 is an antibiotic isolated from fermentations of Streptomyces hagronensis (strain 360). It is effective in vitro against Gram-positive bacteria but not Gram-negative organisms. Synonyms: U 56407; 2,4,6-Decatrienamide, N-(5-hydroxy-5-(7-((2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino)-7-oxo-1,3,5-heptatrienyl)-2-oxo-7-oxabicyclo(4.1.0)hept-3-en-3-yl)-9-methyl-. CAS No. 87695-80-5. Molecular formula: C29H32N2O7. Mole weight: 520.6. BOC Sciences 12
U-57930 A U-57930 is a group of nucleoside antibiotic isolated from Streptomyces rochei (NRRL-3533), which is against gram-positive bacteria and protozoon. Molecular formula: C26H43N5O12SClP. Mole weight: 716.14. BOC Sciences 12
U-57930 B U-57930 is a group of nucleoside antibiotic isolated from Streptomyces rochei (NRRL-3533), which is against gram-positive bacteria and protozoon. Molecular formula: C27H43N7O10SClP. Mole weight: 724.16. BOC Sciences 12
U-57930 C U-57930 is a group of nucleoside antibiotic isolated from Streptomyces rochei (NRRL-3533), which is against gram-positive bacteria and protozoon. Molecular formula: C26H42N4O13SClP. Mole weight: 717.12. BOC Sciences 12
U-57930 D U-57930 is a group of nucleoside antibiotic isolated from Streptomyces rochei (NRRL-3533), which is against gram-positive bacteria and protozoon. Molecular formula: C27H45N4O11SClP. Mole weight: 700.16. BOC Sciences 12
U-58431 U-58431 is an antibiotic isolated from Streptomyces helicus (UC-5837), which is effective against gram-positive and gram-negative bateria, and more potently against streptococcus pneumoniae. It exhibits toxicity. CAS No. 75533-14-1. Molecular formula: C13H14N2O6. Mole weight: 294.26. BOC Sciences 12
U 62066 U 62066 is a selective κ-opioid agonist. It exhibits analgesic, diuretic and antitussive properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 87151-85-7. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H30Cl2N2O2, Molecular Weight: 425.39. US Biological Life Sciences. USBiological 3
Worldwide
U-62162 U-62162 is an antibiotic isolated from the fermentations of Streptomyces verdensis Dietz, sp. n. (UC-8157). It inhibited the growth of Gram-positive bacteria (particularly Staphylococcus aureus) but was inactive in experimentally infected animals. Synonyms: Antibiotic U-62162. CAS No. 82516-67-4. Molecular formula: C23H33NO6. Mole weight: 419.5. BOC Sciences 12
U-68204 U-68204 is a thiolactone-containing metabolite produced by a soil actinomycete identified as Streptomyces thiolactonus UC 8478 (NRRL 15,439). It exhibited mild antibacterial activity with CD50 of 50mg/kg for inhibition of bacillus influenzae. CAS No. 98352-22-8. Molecular formula: C13H17NO3S. Mole weight: 267.35. BOC Sciences 12
U-69593 U-69593 is a potent and selective κ1-opioid receptor agonist[1]. U-69593 attenuates addictive agent-induced behavioral sensitization in the rat[2]. U-69593 reduces anxiety and enhances spontaneous alternation memory in mice[3]. U-69593 reduces calcium-dependent dialysate levels of dopamine and glutamate in the ventral striatum[4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 96744-75-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-12363. MedChemExpress MCE
U-73122 U73122 is a potent phospholipase C (PLC) inhibitor, which reduces agonist-induced Ca2+ increases in platelets and PMN. U73122 potently inhibits human 5-lipoxygenase (5-LO). Group: Inhibitors. CAS No. 112648-68-7. Pack Sizes: 5mg. Product ID: S8011. Formula: C29H40N2O3. Smiles: CC12CCC3C(C1CCC2NCCCCCCN4C(=O)C=CC4=O)CCC5=C3C=CC(=C5)OC. Storage Conditions: 2 years -80 in solvent. Selleck Chemicals
United States; Europe
U-73122 U-73122 is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with an IC50of 1-2.1 μM for PLC. Uses: Scientific research. Category: Signaling pathways. CAS No. 112648-68-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13419. MedChemExpress MCE
U 73343 U 73343. Group: Biochemicals. Grades: Purified. CAS No. 142878-12-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
U-73343 U-73343, works as a protonophore, is an inactive analog of U-73122 and can be used as a negative control. U-73343 dose-dependently inhibits acid secretion irrespective of the stimulant. U-73122 is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with an IC50 of 1-2.1 μM for PLC[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 142878-12-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-108630. MedChemExpress MCE
U-77802 Paulomycin A is a metabolite produced by Streptomyces paulus strain 273. It exhibits mild activity against gram-positive bacteria. Synonyms: U-77802; U-77,802; U 77802; U 77,802. CAS No. 118625-41-5. Molecular formula: C34H48N2O17S2. Mole weight: 820.9. BOC Sciences 12
U-77803 Paulomycin B is a metabolite produced by Streptomyces paulus strain 273. It exhibits mild activity against gram-positive bacteria. Synonyms: U-77803; U-77,803; U 77803; U 77,803. CAS No. 118625-40-4. Molecular formula: C33H46N2O17S2. Mole weight: 806.9. BOC Sciences 12
U7D-1 U7D-1 is a first-in-class potent and selective USP7 (ubiquitin-specific protease 7) PROTAC degrader, with a DC50 of 33 nM in RS4;11 cells. U7D-1 shows anticancer activity. U7D-1 induces apoptosis in Jeko-1 cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3094177-94-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148369. MedChemExpress MCE
U87 Transfection Reagent Transfection Reagent for U87 Glioblastoma Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 3278. Altogen
Nevada, Texas, USA
U 89843A U 89843A. Group: Biochemicals. Grades: Purified. CAS No. 157013-85-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
U 90042 U 90042. Group: Biochemicals. Grades: Purified. CAS No. 134516-99-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
U 93631 U 93631. Group: Biochemicals. Grades: Purified. CAS No. 152273-12-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
U 99194 maleate U 99194 maleate. Group: Biochemicals. Grades: Purified. CAS No. 234757-41-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
UA 62784 UA 62784. Group: Biochemicals. Grades: Purified. CAS No. 313367-92-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
U Acetic acid A nucleobase for PNA synthesis. Synonyms: (2,4-Dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetic acid; 2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid; (2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid. Grade: 98%. CAS No. 4113-97-7. Molecular formula: C6H6N2O4. Mole weight: 170.12. BOC Sciences 11
UAMC 00039 dihydrochloride UAMC 00039 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 697797-51-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
UAMC-1110 UAMC-1110 is a highly potent and selective inhibitor of fibroblast activation protein (FAP) with an IC50 of 3.2 nM. UAMC-1110 also inhibits prolyl oligopeptidase (PREP) with an IC50 of 1.8 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1448440-52-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100684. MedChemExpress MCE
UAMC-3203 UAMC-3203 is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FXT-001. CAS No. 2271358-64-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112909. MedChemExpress MCE
UAMC-3203 hydrochloride UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FXT-001 hydrochloride. CAS No. 2271358-65-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112909A. MedChemExpress MCE
UBA5-IN-1 UBA5-IN-1 (compound 8.5) is a selective UBA5 inhibitor with an IC50 value of 4.0 μM. UBA5-IN-1 inhibits cell proliferation of Sk-Luci6 cancer cells with high expression levels of UBA5[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1831169-11-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148266. MedChemExpress MCE
Ubamatamab Ubamatamab (REGN4018) is a humanized bispecific antibody targeted against Mucin 16 (MUC16) and CD3. Ubamatamab demonstrates potent antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: REGN4018. CAS No. 2305629-50-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99539. MedChemExpress MCE
UBCS039 UBCS039 is the first synthetic, specific Sirtuin 6 (SIRT6) activator, inducing autophagy in human tumor cells, with an EC50 of 38 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 358721-70-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115453. MedChemExpress MCE
UBE2T/FANCL-IN-1 UBE2T/FANCL-IN-1 is a potent inhibitor of UBE2T/FANCL-mediated FANCD2 monoubiquitylation that sensitizes cells to the DNA cross-linking agent, Carboplatin[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1359415-02-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126539. MedChemExpress MCE
Ubenimex 250mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C16H24N2O4. CAS No. 58970-76-6. Prepack ID 89989951-250mg. Molecular Weight 308.37. See USA prepack pricing. Molekula Americas
Ubenimex Ubenimex (INN), also known more commonly as bestatin, is a competitive, reversible protease inhibitor. It is an inhibitor of arginyl aminopeptidase (aminopeptidase B), leukotriene A4 hydrolase (a zinc metalloprotease that displays both epoxide hydrolase and aminopeptidase activities), alanyl aminopeptidase (aminopeptidase M/N), leucyl/cystinyl aminopeptidase (oxytocinase/vasopressinase), and membrane dipeptidase (leukotriene D4 hydrolase). It is being studied for use in the treatment of acute myelocytic leukemia. It is derived from Streptomyces olivoreticuli. Ubenimex has been found to inhibit the enzymatic degradation of oxytocin, vasopressin, enkephalins, and various other peptides and compounds. Alternative Names: 3-(r)-amino-2-(s)-hydroxy-4-phenylbutanoyl-(s)-leucine;n-(3-amino-2-hydroxy-1-oxo-4-phenylbutyl)-,(s-(r*,s*))-l-leucin;nk421;UBENIMEX;N-[(2S,3R)-3-AMINO-2-HYDROXY-1-OXO-4-PHENYLBUTYL]-L-LEUCINE;N-((2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRYL)-L-LEUCINE;[(2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRYL]-L-LEUCINE;[(2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTANOYL]-LEU. CAS No. 58970-76-6. Purity: 99%. Product ID: ACM58970766. Molecular formula: C16H24N2O4. Mole weight: 308.37. IUPAC Name: (2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoicacid. Canonical SMILES: CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O. ECNumber: 261-529-2. Alfa Chemistry - ISO 9001:32057 Certified. Alfa Chemistry.
Ubenimex Bestatin is a natural, broad-spectrum, and competitive aminopeptidase inhibitor. Category: Active pharmaceutical ingredients. CAS No. 58970-76-6. Product ID: API58970766. Molecular formula: C16H24N2O4. Mole weight: 308.4. Appearance: Crystalline or powder. Protheragen
UBE Polyethylene UBE Polyethylene. Alfa Chemistry Materials 6
Ubidecarenone Related Compound A Ubidecarenone Related Compound A. Uses: For analytical and research use. CAS No. 303-97-9. Mole weight: 795.23. Catalog: AP303979-A. Alfa Chemistry Analytical Products
Ubiquicidin Ubiquicidin is a synthetic cationic antimicrobial peptide. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Lys-Val-His-Gly-Ser-Leu-Ala-Arg-Ala-Gly-Lys-Val-Arg-Gly-Gln-Thr-Pro-Lys-Val-Ala-Lys-Gln-Glu-Lys-Lys-Lys-Lys-Lys-Thr-Gly-Arg-Ala-Lys-Arg-Arg-Met-Gln-Tyr-Asn-Arg-Arg-Phe-Val-Asn-Val-Val-Pro-Thr-Phe-Gly-Lys-Lys-Lys-Gly-Pro-Asn-Ala-Asn-Ser. Mole weight: 6648. BOC Sciences 11
Ubiquinol Reduced coenzyme Q for improving nervous system cell functions. Group: Biochemicals. Alternative Names: 2-[(2E, 6E, 10E, 14E, 18E, 22E, 26E, 30E, 34E)-3, 7, 11, 15, 19, 23, 27, 31, 35, 39-Decamethyl-2, 6, 10, 14, 18, 22, 26, 30, 34, 38-tetracontadecaen-1-yl]-5, 6-dimethoxy-3-methyl- 1,4-benzenediol; Dihydrocoenzyme Q10; Reduced Coenzyme Q10; Reduced Ubiquinone Q10; Ubiquinol 50. Grades: Highly Purified. CAS No. 992-78-9. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 3
Worldwide
Ubiquinol United States Pharmacopeia (USP) Reference Standard. Uses: For analytical and research use. Category: Pharmacopeia & metrological institutes standards. CAS No. 992-78-9. Mole weight: 865.36. Catalog: AP992789. Alfa Chemistry Analytical Products
Ubiquinol Ubiquinol. CAS No: 992-78-9 Sarchem Laboratories
Sarchem Laboratories New Jersey NJ
ubiquinol oxidase (electrogenic, non H+-transporting) This terminal oxidase enzyme is unable to pump protons but generates a proton motive force by transmembrane charge separation resulting from utilizing protons and electrons originating from opposite sides of the membrane to generate water. The bioenergetic efficiency (the number of charges driven across the membrane per electron used to reduce oxygen to water) is 1. The bd-I oxidase from the bacterium Escherichia coli is the predominant respiratory oxygen reductase that functions under microaerophilic conditions in that organism. cf. EC 1.10.3.10, ubiquinol oxidase (H+-transporting). Group: Enzymes. Synonyms: cytochrome bd-I oxidase; cydA (gene name); cydB (gene name); ubiquinol:O2 oxidoreductase (electrogenic, non H+-transporting). Enzyme Commission Number: EC 7.1.1.7 (Formerly EC 1.10.3.14). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0480; ubiquinol oxidase (electrogenic, non H+-transporting); EC 1.10.3.14; cytochrome bd-I oxidase; cydA (gene name); cydB (gene name); ubiquinol:O2 oxidoreductase (electrogenic, non H+-transporting). Cat No: EXWM-0480. Creative Enzymes
ubiquinol oxidase (H+-transporting) Contains a dinuclear centre comprising two hemes, or heme and copper. This terminal oxidase enzyme generates proton motive force by two mechanisms: (1) transmembrane charge separation resulting from utilizing protons and electrons originating from opposite sides of the membrane to generate water, and (2) active pumping of protons across the membrane. The bioenergetic efficiency (the number of charges driven across the membrane per electron used to reduce oxygen to water) depends on the enzyme; for example, for the bo3 oxidase it is 2, while for the bd-II oxidase it is 1. cf. EC 1.10.3.14, ubiquinol oxidase (electrogenic, non H+-transporting). Group: Enzymes. Synonyms: cytochrome bb3 oxidase; cytochrome bo oxidase; cytochrome bd-II oxidase; ubiquinol:O2 oxidoreductase (H+-transporting). Enzyme Commission Number: EC 7.1.1.3 (Formerly EC 1.10.3.10). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0476; ubiquinol oxidase (H+-transporting); EC 1.10.3.10; cytochrome bb3 oxidase; cytochrome bo oxidase; cytochrome bd-II oxidase; ubiquinol:O2 oxidoreductase (H+-transporting). Cat No: EXWM-0476. Creative Enzymes
ubiquinol oxidase (non-electrogenic) The enzyme, described from the mitochondria of plants and some fungi and protists, is an alternative terminal oxidase that is not sensitive to cyanide inhibition and does not generate a proton motive force. Unlike the electrogenic terminal oxidases that contain hemes (cf. EC 1.10.3.10 and EC 1.10.3.14), this enzyme contains a dinuclear non-heme iron complex. The function of this oxidase is believed to be dissipating excess reducing power, minimizing oxidative stress, and optimizing photosynthesis in response to changing conditions. Group: Enzymes. Synonyms: plant alternative oxidase; cyanide-insensitive oxidase; AOX (gene name); ubiquinol oxidase; ubiquinol:O2 oxidoreductase (non-electrogenic). Enzyme Commission Number: EC 1.10.3.11. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0477; ubiquinol oxidase (non-electrogenic); EC 1.10.3.11; plant alternative oxidase; cyanide-insensitive oxidase; AOX (gene name); ubiquinol oxidase; ubiquinol:O2 oxidoreductase (non-electrogenic). Cat No: EXWM-0477. Creative Enzymes
Ubiquinone-1 Ubiquinone-1 is an intermediate in the synthesis of Coenzyme Q. Ubiquinone-1 can be reduced by NADPH oxidase, hepatoma cells, Ascorbic acid (HY-B0166)[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 727-81-1. Pack Sizes: 1 mg (40 mM * 100 μL in Ethanol); 5 mg (40 mM * 500 μL in Ethanol); 10 mg (40 mM * 1 mL in Ethanol); 25 mg (40 mM * 2.5 mL in Ethanol); 50 mg (40 mM * 5 mL in Ethanol); 100 mg (40 mM * 10 mL in Ethanol). Product ID: HY-113449. MedChemExpress MCE
Ubiquinone-10 Ubiquinone-10 acts as an inhibitor of the mitochondrial permeability transition pore (MPTP). This inhibitory effect can be counteracted by ubiquinone-5. Applications: An inhibitor of the mitochondrial permeability transition pore. Group: Coenzymes. Synonyms: Coenzyme Q2; 2,3-Dimethoxy-5-methyl-6-geranyl-1,4-benzoquinone. CAS No. 606-06-4. Purity: ≥90%. Mole weight: 318.4. Form: Liquid. Coenzyme Q2; 2,3-Dimethoxy-5-methyl-6-geranyl-1,4-benzoquinone; Ubiquinone-10; 606-06-4. Cat No: COEC-062. Creative Enzymes
Ubiquinone-5 Ubiquinone-5 is a coenzyme Q10 (CoQ10) (sc-205262) analog that counteracts the inhibitory effects on mitochondrial permeability transition pore (MPTP) of decylubiquinone and ubiquinone-10. Applications: A coq10 analog that counteracts the inhibitory effects on mptp. Group: Coenzymes. Synonyms: Coenzyme Q1. CAS No. 727-81-1. Mole weight: 250.29. Form: Liquid. Coenzyme Q1; Ubiquinone-5; 727-81-1. Cat No: COEC-012. Creative Enzymes
Ubiquitin Antibody [J9C13] Ub,Ubiquitin,Ubiquitinylated proteins. Group: Antibodies. Alternative Names: Ub,Ubiquitin,Ubiquitinylated proteins. Pack Sizes: 20ul. Product ID: F0109. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. Selleck Chemicals
United States; Europe
Ubiquitination Compound Library A unique collection of 214 ubiquitination related small chemicals can be used for high throughput and high content screening?- Targets include proteasome, E1/E2/E3 Enzyme, DUB, p97, etc. ; - Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L8600. Categories: Ubiquitination Compounds Libraries. TARGETMOL CHEMICALS
Ubiquitination-IN-1 Ubiquitination-IN-1 (compound 24) is a ubiquitination and Cksl-Skp2 protein-protein interaction (IC50=0.17 μM) inhibitor. Ubiquitination-IN-1 increases levels of p27. Ubiquitination-IN-1 has the potential for treatment disease by blocking the degradation of tumor suppressors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1819330-15-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135199. MedChemExpress MCE
Ubiquitin Isopeptidase Inhibitor I, G5 Ubiquitin Isopeptidase Inhibitor I, G5 (NSC 144303) is an apoptosome-independent caspase and apoptosis activator with IC50 values of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC144303. CAS No. 108477-18-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100738. MedChemExpress MCE
Ubiquitin (linkage-specific Lys 63) Antibody [J20H12] K63-linkage Specific Polyubiquitin,Ubiquitin (linkage-specific K63),Ub-K63. Group: Antibodies. Alternative Names: K63-linkage Specific Polyubiquitin,Ubiquitin (linkage-specific K63),Ub-K63. CAS No. Pack Sizes: 20uL. Product ID: F0528. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. Selleck Chemicals
United States; Europe
ubiquitinyl hydrolase 1 Links to polypeptides smaller than 60 residues are hydrolysed more readily than those to larger polypeptides. Isoforms exist with quantitatively different specificities, amongst the best known being UCH-L1 and UCH-L3, which are major proteins of the brain of mammals. Inhibited by ubiquitin aldehyde (in which Gly76 is replaced by aminoacetaldehyde). Ubiquitinyl hydrolase 1 is the type example of peptidase family C12, with a similar protein fold to papain and catalytic amino acids Cys, His and Asp. There is a separate family (C19) of enzymes that also hydrolyse ubiquitinyl bonds, and it is thought that all the ubiquitinyl hydrolases are also ubiquitin thiolesterases (EC 3.1.2.15). Group: Enzymes. Synonyms: ubiquitin C-terminal hydrolase; yeast ubiquitin hydrolase. Enzyme Commission Number: EC 3.4.19.12. CAS No. 86480-67-3, 189642-63-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4084; ubiquitinyl hydrolase 1; EC 3.4.19.12; 86480-67-3, 189642-63-5; ubiquitin C-terminal hydrolase; yeast ubiquitin hydrolase. Cat No: EXWM-4084. Creative Enzymes
Ublituximab Ublituximab (LFB-R603; TG-1101; TGTX-1101) is a next-generation, type 1 chimeric monoclonal antibody targeting a unique epitope on the CD20 antigen. Ublituximab has anticancer effects[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LFB-R603; TG-1101; TGTX-1101. CAS No. 1174014-05-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99538. MedChemExpress MCE

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