A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
A potent antagonist highly selective for GluK1 (Kb = 10nM), GluK3 (IC50 = 23nM), and GluK1/K5 (Kb = 8nM) subtype kainate receptors. Does not interact with GluK2 and GluK2/K5 receptors. Low affinity to AMPA receptors (Kd = 83uM). Does not interact with mGluR1 ornMDA receptors at concentration less than 10uM. Often used in studying neuronal excitability and synaptic plasticity. Group: Biochemicals. Grades: Highly Purified. CAS No. 902464-46-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
UBP316
UBP316 (ACET) is a highly potent and selective kainate receptor GluK1 (GluR5) antagonist, with a Kb value of 1.4 nM. UBP316 is effective at blocking the depression of both field excitatory postsynaptic potentials (fEPSPs) and monosynaptically-evoked GABAergic transmission induced by ATPA, a GluK1 selective agonist[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACET. CAS No. 936095-50-0. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107601.
Ubretid
Ubretid is a potent inhibitor of plasma cholinesterase. Ubretid therefore delays the hydrolysis of suxamethonium and prolongs its action, similar to the effects shown by other anticholinesterase agents, such as pyridostigmine and donepezil. Ubretid has the potential for the research of urinary retention prolongs the effect of suxamethonium. Ubretid is commonly prescribed for the research of myasthenia gravis and for difficulty in emptying the bladder[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Distigmine dibromide. CAS No. 15876-67-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-119577.
Ubrogepant
Ubrogepant (MK-1602) is an orally active and selective antagonist of calcitonin gene-related peptide receptor (CGRP). Ubrogepant has high affinity for CGRP receptors in human and rhesus monkeys, and can effectively block the cAMP response stimulated by α-CGRP. Ubrogepant can be used in the study of acute migraine[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-1602. CAS No. 1374248-77-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12366.
UBX1325
UBX1325 is an Bcl-xL inhibitor that promotes apoptosis in senescent cells. UBX1325 is a potent anti-aging agent that can be used in studies of age-related eye diseases such as diabetic macular oedema (DME), age-related macular degeneration (AMD) and diabetic retinopathy (DR)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2271269-01-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150069.
UBX domain-containing protein 11 (447-460)
UBX domain-containing protein 11 (447-460) is a peptide derived from UBX domain-containing protein 11. UBX domain-containing protein 11 is involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. It promotes RHOA activation mediated by GNA12 and GNA13. Synonyms: Colorectal tumor-associated antigen COA-1 (447-460); UBX domain-containing protein 5 (447-460).
UC 112
UC 112. Group: Biochemicals. Grades: Purified. CAS No. 383392-66-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
UC-1728
UC-1728 is a potent rabbit soluble epoxide hydrolase (sEH) inhibitor, with an IC50 of 2 nM on rabbit liver. Uses: Scientific research. Category: Signaling pathways. Alternative Names: t-TUCB. CAS No. 948304-40-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114266.
UC2288
UC2288 is a potent and orally active p21 attenuator (relatively selective activity for p21), which is synthesized based Sorafenib (HY-10201). UC2288 potently inhibits cancer cell growth by inducing apoptosis. UC2288 has no inhibition of VEGFR2 and Raf kinases even at 10 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1394011-91-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-112780.
UC2288
UC2288 is a novel, cell-permeable, and orally active p21 attenuator, decreases p21 mRNA expression independently of p53, and attenuates p21 protein levels with minimal effect on p21 protein stability. Group: Inhibitors. CAS No. 1394011-91-6. Pack Sizes: 5mg. Product ID: E1190. Formula: C20H18ClF6N3O2. Smiles: FC(F)(F)C1=CC=C(OC2CCC(CC2)NC(=O)NC3=CC(=C(Cl)C=C3)C(F)(F)F)N=C1. Storage Conditions: 3 years -20°C powder.
United States; Europe
UC-514321
UC-514321, a structural analog of NSC370284 with higher activity, directly targets STAT3/5 and represses TET1 expression, but not TET2 or TET3. UC-514321 has the potential to treat acute myeloid leukemia (AML) both in vitro and in vivo, with low toxicity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 299420-83-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120395.
UC-764864
UC-764864 is a selective UBE2N inhibitor. UC-764864 covalently binds UBE2N catalytic Cys87, blocks ubiquitin-UBE2N thioester formation and polyubiquitin chain synthesis. UC-764864 blocks ubiquitination of innate immune- and inflammatory-related substrates, and induces cell apoptosis. UC-764864 can be used for the research of acute myeloid leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 278806-03-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153775.
UCA 1064-A
UCA 1064-A is an antitumor antibiotic isolated from Wallemia sebi, which inhibits HeLa S3 cells with IC50 of 12.7 μmol/L, suppresses saccharomyces cerevisiae and gram-positive bacteria with MIC of 0.05 and 40 μg/mL, respectively. Molecular formula: C28H45NO. Mole weight: 411.66.
UCA 1064-B
UCA 1064-B is an antitumor antibiotic isolated from Wallemia sebi, which inhibits HeLa S3 cells with IC50 of 14.8 μmol/L, suppresses saccharomyces cerevisiae and gram-positive bacteria with MIC of 0.39 and 40 μg/mL, respectively. Molecular formula: C28H47NO. Mole weight: 413.68.
Ucar Solution Vinyl Resin 9003-22-9
Ucar Solution Vinyl Resin - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
UCB 35625
UCB 35625. Group: Biochemicals. Grades: Purified. Pack Sizes: 1mg, 10mg. US Biological Life Sciences.
Worldwide
UCB-5307
UCB-5307 is a potent TNF signaling inhibitor with a KD of 9 nM for human TNFα. UCB-5307 can penetrate the preformed hTNF/hTNFR1 complex[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1515887-44-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147045.
UCB-6876
UCB-6876 is a TNFα inhibitor. UCB-6876 specifically binds to the asymmetric crystalline form of TNF-α trimer with a KD of 22 μM. UCB-6876 is applicable to research related to autoimmune diseases (rheumatoid arthritis and Crohn's disease)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 637324-45-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156454.
UCB-9260
UCB-9260, an orally active compound, inhibits TNF signaling by stabilising an asymmetric form of the trimer. UCB-9260 is selective for TNF over other superfamily members, and binds TNF with a similar Kd of 13?nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1515888-53-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133122.
UCB9386
UCB9386 is the selective and brain penetrant inhibitor for Nuak1 with a pIC50 of 10.1. UCB9386 inhibits Nuak2 and Kak2 with an inhibition rate of ca. 50% at 10 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3096082-93-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-170360.
UCE1022
UCE1022 is a cytotoxin with topoisomerase I mediated DNA cleavage activity. Synonyms: UCE-1022; UCE 1022. CAS No. 158243-10-8. Molecular formula: C18H10O10S. Mole weight: 418.3.
UCE 6
UCE 6 is an antitumor metabolite with topoisomerase I mediated DNA cleavage activity. Synonyms: UCE-6; UCE6. CAS No. 150829-94-0. Molecular formula: C24H20O8. Mole weight: 436.4.
Ucenprubart
Ucenprubart is an anti-CD200R1 human IgG4κ monoclonal antibody[1]. Recommend Isotype Controls: Human IgG4 kappa, Isotype Control (HY-P99003). Uses: Scientific research. Category: Inhibitory antibodies. CAS No. 2414559-57-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990770.
Ucf-101
Ucf-101 is a selective and competitive inhibitor of pro-apoptotic protease Omi/HtrA2, with an IC50 of 9.5 μM for His-Omi. Ucf-101 exhibits very little activity against various other serine proteases (IC50>200 μM). Ucf-101 has a natural red fluorescence at 543 nm that is used to monitor its ability to enter mammalian cells. Ucf-101 has a significant cardioprotective effect against MI/R injury and also has certain neuroprotective effect[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 313649-08-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-125959.
UCF116-A
UCF116-A is a FTase inhibitor produced by Steptomyces sp. Molecular formula: C37H48N2O8. Mole weight: 648.78.
UCF116-B
UCF116-B is a FTase inhibitor produced by Steptomyces sp. Molecular formula: C36H48N2O8. Mole weight: 636.77.
UCF116-C
UCF116-C is a metabolite produced by Steptomyces sp. It is inactive for Ftase. Molecular formula: C34H46N2O8. Mole weight: 610.74.
UCF76-A
UCF76-A is a FTase inhibitor produced by Steptomyces sp. Molecular formula: C19H20O7. Mole weight: 360.36.
UCF76-B
UCF76-B is a FTase inhibitor produced by Steptomyces sp. Molecular formula: C18H16O7. Mole weight: 344.31.
UCF76-C
UCF76-C is a FTase inhibitor produced by Steptomyces sp. Molecular formula: C18H16O6. Mole weight: 328.32.
UCH9
UCH9 is an antitumor antibiotic produced Streptomyces. II. It exhibits bacteriophage and gram-positive bacteria activity. Synonyms: UCH-9; UCH 9. Molecular formula: C55H82O24. Mole weight: 1127.2.
UCK2 Inhibitor-1
UCK2 Inhibitor-1 (Compound 20874830-2) is a non-competitive UCK2 inhibitor with an IC50 of 4.7 μM. UCK2 Inhibitor-1 acts as a non-competitive inhibitor against uridine and ATP, and functionally inhibits the enzymatic activity of UCK2. UCK2 Inhibitor-1 suppresses the uridine salvage pathway. UCK2 Inhibitor-1 can be used in chronic myeloid leukemia research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 902289-98-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148394.
UCK2 Inhibitor-3
UCK2 Inhibitor-3 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2, a pyrimidine salvage enzyme) with an IC50 value of 16.6 μM. UCK2 can replace dihydroorotate dehydrogenase (DHODH), in a certain extent, in infected or rapidly dividing cells to continue efficient uridine salvage. UCK2 Inhibitor-3 also inhibits DNA polymerase eta and kappa with IC50s of 56 μM and 16 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2376687-49-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148396.
UCL 1684 dibromide
UCL 1684 (dibromide) is a first nanomolar, non-peptidic small conductance calcium-activated potassium (SK) channel blocker. UCL 1684 (dibromide) is effective in preventing the development of atrial fibrillation due to potent atrial-selective inhibition of INa. UCL 1684 (dibromide) causes atrial-selective prolongation of ERP secondary to induction of postrepolarization refractoriness[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 199934-16-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108579.
UCL 2077
UCL 2077. Group: Biochemicals. Grades: Purified. CAS No. 918311-87-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
UCL 2077
UCL 2077 is a potassium channel and slow afterhyperpolarization (sAHP) inhibitor. UCL 2077 selectively blocks sAHP channels without affecting L-type Ca2+ currents. UCL 2077 blocks KCNQ1- and KCNQ2-containing K+ channels, decreases erg current amplitude, increases erg deactivation rate. UCL 2077 can be used for the research of hippocampus-dependent memory retrieval deficit and cardiac arrhythmias[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 918311-87-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108592.
UCL-TRO-1938
UCL-TRO-1938 is a potent small molecule allosteric activator of PI3Kα with an EC50 value of approximately 60 μM. UCL-TRO-1938 can induce cell proliferation and has cardioprotective effects from ischaemia reperfusion injury and enhances nerve regeneration following nerve crush[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2919575-27-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-154848.
UCM-1306
UCM-1306 is a potent and orally active human dopamine D1 receptor allosteric modulator (PAM). UCM-1306 increases the endogenous dopamine (DA) maximal effect both in human and mouse D1 receptors. UCM-1306 is not only for improving motor symptoms but also for addressing the key comorbid cognitive impairment associated with long-term Parkinsons disease (PD)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2258608-78-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148867.
UCM 707
UCM 707. Group: Biochemicals. Grades: Purified. CAS No. 390824-20-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
UCN-01
KRX-0601, also known as UCN-01, is a synthetic derivative of staurosporine with antineoplastic activity. It inhibits many phosphokinases, including the serine/threonine kinase AKT, calcium-dependent protein kinase C, and cyclin-dependent kinases. This agent arrests tumor cells in the G1/S of the cell cycle and prevents nucleotide excision repair by inhibiting the G2 checkpoint kinase chk1, resulting apoptosis. Uses: Antineoplastic agents. Synonyms: Antibiotic UCN 01; UCN01; Staurosporine; 7-hydroxystaurosporine; KW-2401; KW 2401; KW2401; (3R,9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one; (+)-UCN-01; KRX 0601; NSC 638850. Grade: >99% by HPLC. CAS No. 112953-11-4. Molecular formula: C28H26N4O4. Mole weight: 482.53.
UCN-02
UCN-02 (7-epi-Hydroxystaurosporine) is a selective protein kinase C (PKC) inhibitor with a PKC IC50 value of 62 nM and a PKA IC50 value of 0.25 μM. UCN-02 can be produced by Streptomyces strain N-126. UCN-02 can be used for the research of breast carcinoma[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 7-epi-Hydroxystaurosporine. CAS No. 121569-61-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 1 mg. Product ID: HY-108262.
UCN-02
UCN-02 is an indolocarbazole isolated from a high staurosporine-producing Streptomyces culture with antineoplastic activity. It inhibits many phosphokinases, including the serine/threonine kinase AKT, calcium-dependent protein kinase C, and cyclin-dependent kinases. Synonyms: Antibiotic UCN 02; UCN02; GNF-Pf-3072; 7-hydroxy-staurosporine; 7-epi-Hydroxystaurosporine; (3S,9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one; [3S-(3α,9α,10β,11β,13α)]-2,3,10,11,12,13-Hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one. Grade: >95% by HPLC. CAS No. 121569-61-7. Molecular formula: C28H26N4O4. Mole weight: 482.53.
UCP1 Antibody [L8P13]
UCP1,UCP-1. Group: Antibodies. Alternative Names: UCP-1. Pack Sizes: 20uL. Product ID: F0765. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years.
United States; Europe
UCPH-101
UCPH-101 is an excitatory amino acid transporter subtype 1 (EAAT1) inhibitor with an IC50 of 0.66 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1118460-77-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10914.
UCPH-102
UCPH-102 is a highly selective EAAT1 inhibitor with an IC50 of 0.43 μM. UCPH-102 exhibits a specific anti-proliferative effect on T-ALL cells. UCPH-102 also shows good blood-brain permeability, which can be used in studies of amyotrophic lateral sclerosis, Alzheimers disease, chronic pain and obsessive compulsive disorder[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1229591-56-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118858.
UCS1025 A
UCS1025 A is an antitumor antibiotic isolated from Acremonium sp. KY4917. It exhibits activity against gram-positive bacteria including Staphylococcus and Enterococcus, and proteusbacillus vulgaris. It also inhibits cell proliferation. Synonyms: UCS 1025A. Molecular formula: C22H29NO5. Mole weight: 387.47.
UCS1025 B
UCS1025 B is an antitumor antibiotic isolated from Acremonium sp. KY4917. It exhibits activity against gram-positive bacteria including Staphylococcus and Enterococcus, and proteusbacillus vulgaris. It also inhibits cell proliferation. The activity of B is much weaker than that of A. Synonyms: UCS 1025B. Molecular formula: C22H29NO6. Mole weight: 403.47.
UCT 1072M1
UCT 1072M1 is a topoisomerase II poison isolated from Aspergillus sp. KY4919, which is toxic to HeLa S3 and Lu-65 cells. Synonyms: UCT1072M1; UCT-1072M1. Molecular formula: C18H12O8. Mole weight: 356.28.
UCT 1072M2
UCT 1072M2 is a topoisomerase II poison isolated from Aspergillus sp. KY4919, which is toxic to HeLa S3 and Lu-65 cells. Synonyms: UCT1072M2; UCT-1072M2. Molecular formula: C20H16O7. Mole weight: 368.34.
UCT 1072M3
UCT 1072M3 is a topoisomerase II poison isolated from Aspergillus sp. KY4919, which is toxic to HeLa S3 and Lu-65 cells. UCT 1072M3 is a diastereomer of UCT 1072M2. Synonyms: UCT1072M3; UCT-1072M3. Molecular formula: C20H16O7. Mole weight: 368.34.
UCT4B
UCT4B is an antitumor antibiotic produced by Streptomyces sp. It exhibits topoisomerase II mediated DNA cleavage activity. It suppresses gram-positive bacteria and Klebsiella pneumoniae with MIC of 4.1 and 2.1 μg/mL, respectively. Synonyms: UCT 4B. CAS No. 143200-52-6. Molecular formula: C20H28O7. Mole weight: 380.4.
Udenafil
Udenafil (DA8159) is a potent, selective and orally active phosphodiesterase type 5 (PDE5) inhibitor. Udenafil also inhibits cGMP hydrolysis and can be used for erectile dysfunction research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DA8159. CAS No. 268203-93-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18253.
Udenafil
An oral phosphodiesterase 5 inhibitor used for the treatment of erectile dysfunction. Group: Biochemicals. Alternative Names: 3- (6, 7-Dihydro-1-methyl-7-oxo-3-propyl -1H-pyrazolo [4, 3-d] pyrimidin-5-yl) -N- [2- (1-methyl-2-pyrrolidinyl) ethyl] -4-propoxy Benzene sulfonamide; DA 8159; Zydena. Grades: Highly Purified. CAS No. 268203-93-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Udenafil-[d7]
Udenafil-[d7] is the labelled analogue of Udenafil. Udenafil is a PDE5 inhibitor used for the treatment of erectile dysfunction. Synonyms: Udenafil D7; 3-(1-Methyl-7-oxo-3-propyl-4,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-4-[(2H7)propyloxy]benzene-1-sulfonamide. Grade: 95% by HPLC; 98% atom D. CAS No. 1175992-76-3. Molecular formula: C25H29D7N6O4S. Mole weight: 523.7.
This enzyme participates in the biosynthetic pathway for UDP-α-D-ManNAc3NAcA (UDP-2,3-diacetamido-2,3-dideoxy-α-D-mannuronic acid), an important precursor of the B-band lipopolysaccharide of Pseudomonas aeroginosa serotype O5 and of the band-A trisaccharide of Bordetella pertussis, both important respiratory pathogens. The enzyme is highly specific as UDP-α-D-GlcNAc, UDP-α-D-GlcNAcA (UDP-2-acetamido-2-deoxy-α-D-glucuronic acid) and UDP-α-D-GlcNAc3NAc (UDP-2,3-diacetamido-2,3-dideoxy-α-D-glucose) cannot act as substrates. Group: Enzymes. Synonyms: UDP-GlcNAc3NAcA 2-epimerase; UDP-α-D-GlcNAc3NAcA 2-epimerase; 2,3-diacetamido-2,3-dideoxy-α-D-glucuronic acid 2-epimerase; WbpI; WlbD. Enzyme Commission Number: EC 5.1.3.23. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5409; UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase; EC 5.1.3.23; UDP-GlcNAc3NAcA 2-epimerase; UDP-α-D-GlcNAc3NAcA 2-epimerase; 2,3-diacetamido-2,3-dideoxy-α-D-glucuronic acid 2-epimerase; WbpI; WlbD. Cat No: EXWM-5409.
UDP-2,3-diacylglucosamine diphosphatase
The enzyme catalyses a step in the biosynthesis of lipid A. Group: Enzymes. Synonyms: UDP-2,3-diacylglucosamine hydrolase; UDP-2,3-diacylglucosamine pyrophosphatase; ybbF (gene name); lpxH (gene name); UDP-2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosamine 2,3-bis[(3R)-3-hydroxymyristoyl]-β-D-glucosaminyl 1-phosphate phosphohydrolase (incorrect). Enzyme Commission Number: EC 3.6.1.54. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4626; UDP-2,3-diacylglucosamine diphosphatase; EC 3.6.1.54; UDP-2,3-diacylglucosamine hydrolase; UDP-2,3-diacylglucosamine pyrophosphatase; ybbF (gene name); lpxH (gene name); UDP-2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosamine 2,3-bis[(3R)-3-hydroxymyristoyl]-β-D-glucosaminyl 1-phosphate phosphohydrolase (incorrect). Cat No: EXWM-4626.
The enzyme is involved in biosynthesis of pseudaminic acid. Group: Enzymes. Synonyms: PseG; UDP-6-deoxy-AltdiNAc hydrolase; Cj1312; UDP-2,4-bis(acetamido)-2,4,6-trideoxy-β-L-altropyranose hydrolase. Enzyme Commission Number: EC 3.6.1.57. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4629; UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose hydrolase; EC 3.6.1.57; PseG; UDP-6-deoxy-AltdiNAc hydrolase; Cj1312; UDP-2,4-bis(acetamido)-2,4,6-trideoxy-β-L-altropyranose hydrolase. Cat No: EXWM-4629.
Part of the biosynthesis of UDP-N-acetyl-L-fucosamine. Isolated from the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. Group: Enzymes. Synonyms: WbjC; Cap5F. Enzyme Commission Number: EC 1.1.1.367. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0284; UDP-2-acetamido-2,6-β-L-arabino-hexul-4-ose reductase; EC 1.1.1.367; WbjC; Cap5F. Cat No: EXWM-0284.
A pyridoxal 5'-phosphate protein. This enzyme participates in the biosynthetic pathway for UDP-α-D-ManNAc3NAcA (UDP-2,3-diacetamido-2,3-dideoxy-α-D-mannuronic acid), an important precursor of B-band lipopolysaccharide. The enzymes from Pseudomonas aeruginosa serotype O5 and Thermus thermophilus form a complex with the previous enzyme in the pathway, EC 1.1.1.335 (UDP-N-acetyl-2-amino-2-deoxyglucuronate oxidase). Group: Enzymes. Synonyms: WbpE; WlbC. Enzyme Commission Number: EC 2.6.1.98. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2939; UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase; EC 2.6.1.98; WbpE; WlbC. Cat No: EXWM-2939.
This enzyme participates in the biosynthetic pathway for UDP-α-D-ManNAc3NAcA (UDP-2,3-diacetamido-2,3-dideoxy-α-D-mannuronic acid), an important precursor of B-band lipopolysaccharide. Group: Enzymes. Synonyms: WbpD; WlbB. Enzyme Commission Number: EC 2.3.1.201. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2146; UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase; EC 2.3.1.201; WbpD; WlbB. Cat No: EXWM-2146.
The enzyme catalyses a step of lipid A biosynthesis. LpxD from Escherichia prefers (R,S)-3-hydroxytetradecanoyl-[acyl-carrier protein] over (R,S)-3-hydroxyhexadecanoyl-[acyl-carrier protein]. Escherichia coli lipid A acyltransferases do not have an absolute specificity for 14-carbon hydroxy fatty acids but can transfer fatty acids differing by one carbon unit if the fatty acid substrates are available. When grown on 1% propionic acid, lipid A also contains the odd-chain fatty acids tridecanoic acid, pentadecanoic acid, hydroxytridecanoic acid, and hydroxypentadecanoic acid. Group: Enzymes. Synonyms: UDP-3-O-acyl-glucosamine N-acyltransferase; UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase; acyltransfer. Enzyme Commission Number: EC 2.3.1.191. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2134; UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; EC 2.3.1.191; UDP-3-O-acyl-glucosamine N-acyltransferase; UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase; acyltransferase LpxD; acyl-ACP:UDP-3-O-(3-hydroxyacyl)-GlcN N-acyltransferase; firA (gene name); lpxD (gene name); (3R)-3-hydroxymyristoyl-[acyl-carrier protein]:UDP-3-O-[(3R)-3-hydroxymyristoyl]-α-D-glucosamine N-acetyltransferase. Cat No: EXWM-2134.