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Urocortin III is a neuropeptide hormone and a member of the corticotropin-releasing factor (CRF) family. Urocortin III is a highly selective agonist of the CRF2 receptor and does not show affinity for the CRF binding protein. Grades: ≥95%. Molecular formula: C185H307N53O50S2·xCF3COOH. Mole weight: 4137.88.
Urocortin III, mouse
Urocortin III a neuropeptide hormone and a member of the corticotropin-releasing factor (CRF) family, is a highly selective agonist of the CRF2 receptor and does not show affinity for the CRF binding protein. Synonyms: STRESSCOPIN (3-40) (MOUSE). CAS No. 357952-10-4. Molecular formula: C186H312N52O52S2. Mole weight: 4172.97.
Urocortin III, mouse TFA
Urocortin III, mouse TFA is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III preferentially binds and activates CRF-R2[1]. Urocortin III (Ucn3) is a known component of the behavioral stress response system. Urocortin III and CRF-R2 in the medial amygdala regulate complex social dynamics[2]. Uses: Scientific research. Group: Peptides. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1858A.
Urocortin III (mouse) trifluoroacetate salt
Urocortin III is a neuropeptide hormone and a member of the corticotropin-releasing factor (CRF) family. Urocortin III is a highly selective agonist of the CRF2 receptor and does not show affinity for the CRF binding protein. Grades: ≥95%. Molecular formula: C186H311N51O53S2·xCF3COOH. Mole weight: 4173.90.
Urocortin II (mouse)
Urocortin II (mouse) shows considerably high affinity for two splice variants of type 2 CRF receptor (CRF-R2) compared to CRF-R1. It activates CRF-R2α and CRF-R2β with almost the same potency as urocortin (rat). Synonyms: Ucn II (mouse); H-Val-Ile-Leu-Ser-Leu-Asp-Val-Pro-Ile-Gly-Leu-Leu-Arg-Ile-Leu-Leu-Glu-Gln-Ala-Arg-Tyr-Lys-Ala-Ala-Arg-Asn-Gln-Ala-Ala-Thr-Asn-Ala-Gln-Ile-Leu-Ala-His-Val-NH2. Grades: ≥95%. CAS No. 330648-32-3. Molecular formula: C187H320N56O50. Mole weight: 4152.95.
Urocortin II (mouse) trifluoroacetate salt
Urocortin II is a neuropeptide hormone that is a member of the corticotropin-releasing factor (CRF) family. Urocortin II is a highly selective agonist of the CRF2 receptor and does not show affinity for the CRF binding protein. Grades: ≥95%. Molecular formula: C187H320N56O50·xCF3COOH. Mole weight: 4152.89.
Urocortin (rat)
Urocortin (rat) is a neuropeptide hormone that acts as an endogenous CRF agonist (Ki = 13, 1.5 and 0.97 nM for hCRF1, rCRF2α and mCRF2β, respectively). Synonyms: Urocortin (Rattus norvegicus); Rat urocortin. CAS No. 171543-83-2. Molecular formula: C206H338N62O64. Mole weight: 4707.31.
Uroguanylin belongs to the guanylin family of cyclic guanosine monophosphate (cGMP) regulatory peptides. Uroguanylin activates the guanylate cyclase-C/cyclic guanosine monophosphate pathway to induce analgesic effects in colonic hypersensitive animal models, revealing a new approach for the treatment of abdominal pain. Synonyms: Uroguanylin Topoisomer A (human); UGN Topoisomer A (human); H-Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu-OH (Disulfide bridge: Cys4-Cys12, Cys7-Cys15); UGN (human); L-asparagyl-L-alpha-aspartyl-L-alpha-aspartyl-L-cysteinyl-L-alpha-glutamyl-L-leucyl-L-cysteinyl-L-valyl-L-asparagyl-L-valyl-L-alanyl-L-cysteinyl-L-threonyl-glycyl-L-cysteinyl-L-leucine (4->12),(7->15)-bis(disulfide); L-Asparaginyl-L-α -aspartyl-N-{(1R, 4S, 7S, 10S, 13S, 16R, 19S, 22S, 25R, 32S, 38R)-10-(2-amino-2-oxoethyl)-22-(2-carboxyethyl)-38-{[(1S)-1-carboxy-3-methylbutyl]carbamoyl}-32-[(1R)-1-hydroxyethyl]-19-isobutyl-7, 13-diisopropyl-4-methyl-3, 6, 9, 12, 15, 18, 21, 24, 30, 33, 36-undecaoxo-27, 28, 40, 41-tetrathia-2, 5, 8, 11, 14, 17, 20, 23, 31, 34, 37-undecaazabicyclo[14. 13. 13]dotetracont-25-yl}-L-α -asparagine. Grades: ≥90% by HPLC. CAS No. 154525-25-4. Molecular formula: C64H102N18O26S4. Mole weight: 1667.86.
Uroguanylin (human)
Uroguanylin (human) is a natural ligand for the Guanylyl Cyclase (GCC) receptor expressed in metastatic colorectal cancer tumors. Uroguanylin (human) has anti-tumor actions in an animal model for human colon cancer[1][2]. Uses: Scientific research. Group: Peptides. CAS No. 154525-25-4. Pack Sizes: 500 ?g; 1 mg; 5 mg. Product ID: HY-P3099.
Uroguanylin Topoisomer B (human)
Uroguanylin is a short peptide containing two disulfide bonds that can form interconversion topological isomers with the same disulfide connectivity. In the case of uroguanylin (UGN), both are relatively stable, separable, and slow to transform into each other. Different topoisomers have different biological activities: UGN A topomer can effectively activate the guanylate cyclase C receptor, mainly found in the intestine. The B topomer is a very weak agonist of this receptor. UGN B has strong natriuretic activity in the kidney. Synonyms: UGN Topoisomer B (human); H-Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu-OH (Disulfide bridge: Cys4-Cys12, Cys7-Cys15). Grades: ≥95%. Molecular formula: C64H102N18O26S4. Mole weight: 1667.88.
Urokinase
25mg Pack Size. Group: Analytical Reagents, Biochemicals. Formula: -. CAS No. 9039-53-6. Prepack ID 13187505-25mg. Molecular Weight -. See USA prepack pricing.
Urokinase from Human, recombinant
Urokinase or Urokinase-type plasminogen activator (uPA) is a serine protease (EC 3.4.21.73). It is secreted as a single-chain zymogen, pro-Urokinase, possessing little or no intrinsic enzymatic activity. The single chain zymogen is converted into the active two chain enzyme (tcuPA) by cleavage of the bond between Lys157 and Ile158. After activation, Urokinase specifically cleaves the proenzyme plasminogen to form the active enzyme plasmin. The active plasmin then catalyzes the breakdown of fibrin polymers of blood clots. Urokinase is involved in a number of biological functions including fibrinolysis, embryogenesis, cell migration, tissue remodeling, ovulation, and wound healing. Additionally, it is a potent marker of invasion and metastasis in a variety of human cancers associated with breast, stomach, colon, bladder, ovary, brain and endometrium. Group: Enzymes. Synonyms: Two chain urokinase-type plasminogen acti. Enzyme Commission Number: EC 3.4.21.73. Purity: > 90% by SDS-PAGE. uPA. Mole weight: 49.3 kDa. Activity: >1500 mU/mg. Storage: Stable at -80°C for at least 1 year as supplied. Store reconstituted aliquots at -80°C. Avoid repeated freeze and thaw cycles. Form: Lyophilized powder. Source: E. coli. Species: Human. Two chain urokinase-type plasminogen activator; tcuPA; PLAU; ATF; UPA; URK; u-PA; BDPLT5; QPD; Urokinase. Cat No: NATE-1690.
Urokinase (peptidolytic) (EC 3.4.21.73) is a serine protease, an inactive form (zymogen) of the serine protease plasminogen. Activation of plasmin triggers a proteolytic cascade reaction, which in turn participates in thrombolysis or extracellular matrix degradation, implicated in vascular disease and cancer-related research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Urokinase-type plasminogen activator; Uronase; Win 22005; Win-Kinase. CAS No. 9039-53-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108904.
Urokinase light yellow powder
100mg Pack Size. Group: Biochemicals. Formula: N/A. CAS No. 9039-53-6. Prepack ID 90029023-100mg. See USA prepack pricing.
Urokinase Substrate III, Fluorogenic
Suitable for the quantitative direct fluorescent assay of urokinase. Group: Fluorescence/luminescence spectroscopy.
Urolithin A
Urolithin A is a urolithin, a type of microflora human metabolite of dietary ellagic acid derivatives, such as ellagitannins.During intestinal metabolism by bacteria, ellagitannins and punicalagins are converted to urolithins, which have unknown biological activity in vivo.Urolithin A glucuronide is found in plasma at low concentrations. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Uro-A;pyran-6-one.html >3,8-Dihydroxy-6H-dibenzopyran-6-one;3,8-dihydroxybenzo[c]chromen-6-one;3,8-Dihydroxyurolithin. Product Category: Inhibitors. Appearance: Olive green powder. CAS No. 1143-70-0. Molecular formula: C13H8O4. Mole weight: 228.2. Purity: 0.98. Density: 1.516 g/cm³. Product ID: ACM1143700. Alfa Chemistry ISO 9001:2015 Certified.
Urolithin A
Urolithin A Inhibitor. Uses: Scientific use. Product Category: T7174. CAS No. 1143-70-0.
Urolithin A
Urolithin A, a gut-microbial metabolite of ellagic acid, exerts anti-inflammatory, antiproliferative, and antioxidant properties. Urolithin A induces autophagy and apoptosis , suppresses cell cycle progression, and inhibits DNA synthesis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 1143-70-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100599.
Urolithin A
Urolithin A is a major metabolite of ellagitannin and exhibits anti-inflammatory and antioxidant properties. Group: Biochemicals. Alternative Names: 3,8-Hydroxydibenzo-α-pyrone; 3,8-Dihydroxyurolithin; 2,7-Dihydroxy-3,4-benzocoumarin; δ-Lactone 2,4,4-Trihydroxy-2-biphenylcarboxylic Acid. Grades: Highly Purified. CAS No. 1143-70-0. Pack Sizes: 50mg. Molecular Formula: C??H?O?. US Biological Life Sciences.
Urolithin A 8-Methyl Ether. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-Hydroxy-8-methoxy-6H-benzo[c]chromen-6-one. Appearance: Light Beige to Very Dark Orange Solid. CAS No. 35233-17-1. Molecular formula: C14H10O4. Mole weight: 242.23. Purity: 0.98. Product ID: ACM35233171. Alfa Chemistry ISO 9001:2015 Certified.
Urolithin B is one of Ellagitannins' slow microbial products, and has anti-inflammatory and anti-inflammatory effects. Urolithin B suppresses NF-κB activity. Urolithin B suppresses JNK , ERK and Akt 's oxidation, and increases AMPK 's oxidation. Urolithin B is also a quantitative change factor for bone and skin quality [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 1139-83-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-126307.
Urolithin C
Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca2+ channel opener and enhances Ca2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation[1][2]. Uses: Scientific research. Group: Natural products. CAS No. 165393-06-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-135897.
Urolithin C
Urolithin C is a chebulic ellagitannins metabolite with antioxidant activity. Synonyms: 6H-Dibenzo[b,d]pyran-6-one, 3,8,9-trihydroxy-. CAS No. 165393-06-6. Molecular formula: C13H8O5. Mole weight: 244.2.
Urolithin D
Urolithin D (3,4,8,9-Tetrahydroxy urolithin) is a colonic metabolite of Ellagitannins and a competitive, reversible, and selective antagonist of the EphA receptor. Urolithin D inhibits EphA2-ephrin-A1 binding with an IC50 of 0.9 ?M. Urolithin D is also a potent antioxidant that scavenges free radicals and repairs oxidized DNA damage. Additionally, Urolithin D suppresses triglyceride accumulation and promotes fatty acid oxidation by activating the AMPK signaling pathway. Urolithin D can be used for research on tumors, metabolic, and inflammatory diseases[1][2][3]. Uses: Scientific research. Group: Natural products. Alternative Names: 3,4,8,9-Tetrahydroxy urolithin. CAS No. 131086-98-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133178.
Urolithin E
Urolithin E is a biological molecule. Uses: Scientific research. Group: Signaling pathways. CAS No. 1453297-45-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W746164.
uronate dehydrogenase
Requires Mg2+. The enzyme, characterized from the bacterium Agrobacterium fabrum, participates in oxidative degradation pathways for galacturonate and glucuronate. The enzyme can only accept the β anomeric form of the substrate. The 1,5-lactone product is rather stable at cytosolic pH and does not hydrolyse spontaneously at a substantial rate. Group: Enzymes. Synonyms: uronate:NAD-oxidoreductase; uronic acid dehydrogenase. Enzyme Commission Number: EC 1.1.1.203. CAS No. 37250-98-9. Uronate dehydrogenase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0108; uronate dehydrogenase; EC 1.1.1.203; 37250-98-9; uronate:NAD-oxidoreductase; uronic acid dehydrogenase. Cat No: EXWM-0108.
Uronate dehydrogenase from Agrobacterium tumefaciens, Recombinant
In enzymology, an uronate dehydrogenase (EC 1.1.1.203) is an enzyme that catalyzes the chemical reaction: D-galacturonate + NAD+ + H2O ? D-galactarate + NADH + H+. The 3 substrates of this enzyme are D-galacturonate, NAD+, and H2O, whereas its 3 products are D-galactarate, NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. Group: Enzymes. Synonyms: uronate:NAD+ 1-oxidoreductase; uronate: NAD-oxidoreductase; uronic acid dehydrogenase; EC 1.1.1.203. Enzyme Commission Number: EC 1.1.1.203. CAS No. 37250-98-9. Purity: >95% as judged by SDS-PAGE. Uronate dehydrogenase. Mole weight: 31.14 kDa. Activity: 3000 U/ml. Storage: Uronate dehydrogenase should be stored at 4 °C or and will remain stable up to 3 years if stored as specified. Form: 3.2 M ammonium sulphate. Source: E. coli. Species: Agrobacterium tumefaciens. uronate:NAD+ 1-oxidoreductase; uronate: NAD-oxidoreductase; uronic acid dehydrogenase; EC 1.1.1.203. Cat No: NATE-1575.
Uronium toluene-p-sulfonate
Uronium toluene-p-sulfonate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MONO-P-TOLUENESULFONATE UREA;uronium toluene-p-sulphonate. Product Category: Heterocyclic Organic Compound. CAS No. 21835-55-2. Molecular formula: C7H8O3S.CH4N2O. Mole weight: 232.26. Product ID: ACM21835552. Alfa Chemistry ISO 9001:2015 Certified. Categories: Urea mono(4-methylbenzenesulfonate).
uronolactonase
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is D-glucurono-6,2-lactone lactonohydrolase. This enzyme is also called glucuronolactonase. This enzyme participates in ascorbate and aldarate metabolism. Group: Enzymes. Synonyms: glucuronolactonase. Enzyme Commission Number: EC 3.1.1.19. CAS No. 9025-93-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3444; uronolactonase; EC 3.1.1.19; 9025-93-8; glucuronolactonase. Cat No: EXWM-3444.
Uroporphyrin i,octamethyl ester
Uroporphyrin i,octamethyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Uroporphyrin I octamethyl ester, U3253_ALDRICH, U3253_SIGMA, CID66288, NSC89197, EINECS 233-444-0, NSC 89197, 10170-03-3, 21H,23H-Porphine-2,7,12,17-tetrapropanoic acid, 3,8,13,18-tetrakis(2-methoxy-2-oxoethyl)-, tetramethyl ester, 21H,23H-Porphine-2,7,12,17-tetraacetic acid, 3,8,13,18-tetrakis(3-methoxy-3-oxopropyl)-, 2,7,12,17-tetramethyl ester, Tetramethyl 3,8,13,18-tetrakis(2-methoxy-2-oxoethyl)-21H,23H-porphine-2,7,12,17-tetrapropionate. Product Category: Heterocyclic Organic Compound. CAS No. 10170-03-3. Molecular formula: C48H54N4O16. Mole weight: 942.96. Purity: 0.96. IUPACName: methyl 3-[3,8,13,18-tetrakis(2-methoxy-2-oxoethyl)-7,12,17-tris(3-methoxy-3-oxopropyl)-21,22-dihydroporphyrin-2-yl]propanoate. Density: 1.293g/cm³. Product ID: ACM10170033. Alfa Chemistry ISO 9001:2015 Certified.
uroporphyrinogen decarboxylase
Acts on a number of porphyrinogens. Group: Enzymes. Synonyms: uroporphyrinogen III decarboxylase; porphyrinogen carboxy-lyase; porphyrinogen decarboxylase; uroporphyrinogen-III carboxy-lyase. Enzyme Commission Number: EC 4.1.1.37. CAS No. 9024-70-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4781; uroporphyrinogen decarboxylase; EC 4.1.1.37; 9024-70-8; uroporphyrinogen III decarboxylase; porphyrinogen carboxy-lyase; porphyrinogen decarboxylase; uroporphyrinogen-III carboxy-lyase. Cat No: EXWM-4781.
uroporphyrinogen-III C-methyltransferase
This enzyme catalyses two sequential methylation reactions, the first forming precorrin-1 and the second leading to the formation of precorrin-2. It is the first of three steps leading to the formation of siroheme from uroporphyrinogen III. The second step involves an NAD+-dependent dehydrogenation to form sirohydrochlorin from precorrin-2 (EC 1.3.1.76, precorrin-2 dehydrogenase) and the third step involves the chelation of Fe2+ to sirohydrochlorin to form siroheme (EC 4.99.1.4, sirohydrochlorin ferrochelatase). In Saccharomyces cerevisiae, the last two steps are carried out by a single bifunctional enzyme, Met8p. In some bacteria, steps 1-3 are catalysed by a single mult...(incorrect). Enzyme Commission Number: EC 2.1.1.107. CAS No. 125752-76-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1705; uroporphyrinogen-III C-methyltransferase; EC 2.1.1.107; 125752-76-3; uroporphyrinogen methyltransferase; uroporphyrinogen-III methyltransferase; adenosylmethionine-uroporphyrinogen III methyltransferase; S-adenosyl-L-methionine-dependent uroporphyrinogen III methylase; uroporphyrinogen-III methylase; SirA; CysG; CobA [ambiguous - see EC 2.5.1.17] SUMT; uroporphyrin-III C-methyltransferase (incorrect); S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase
uroporphyrinogen-III synthase
In the presence of EC 2.5.1.61, hydroxymethylbilane synthase, the enzyme forms uroporphyrinogen III from porphobilinogen. Group: Enzymes. Synonyms: porphobilinogenase; uroporphyrinogen isomerase; uroporphyrinogen III cosynthase; URO-synthase; hydroxymethylbilane hydro-lyase (cyclizing). Enzyme Commission Number: EC 4.2.1.75. CAS No. 37340-55-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5059; uroporphyrinogen-III synthase; EC 4.2.1.75; 37340-55-9; porphobilinogenase; uroporphyrinogen isomerase; uroporphyrinogen III cosynthase; URO-synthase; hydroxymethylbilane hydro-lyase (cyclizing). Cat No: EXWM-5059.
Urosodeoxycholic Acid EP Impurity G
Urosodeoxycholic Acid EP Impurity G. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10538-55-3. Molecular formula: C25H42O4. Mole weight: 406.61. Catalog: APB10538553.
Urosodeoxycholic Acid EP Impurity N
Urosodeoxycholic Acid EP Impurity N. Uses: For analytical and research use. Group: Impurity standards. CAS No. 13222-48-5. Molecular formula: C26H46NO7P. Mole weight: 515.61. Catalog: APB13222485.
Urosodeoxycholic Acid EP Impurity T
Urosodeoxycholic Acid EP Impurity T. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1534-35-6. Molecular formula: C24H40O3. Mole weight: 376.58. Catalog: APB1534356.
Urosodeoxycholic Acid Impurity 23
Urosodeoxycholic Acid Impurity 23. Uses: For analytical and research use. Group: Impurity standards. CAS No. 105227-28-9. Molecular formula: C24H40O4. Mole weight: 392.58. Catalog: APB105227289.
Urotensin I
Urotensin I is, 41-aa neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2α receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2α and mCRF2β receptors, respectively. Synonyms: Catostomus urotensin I. CAS No. 83930-33-0. Molecular formula: C210H340N62O67S2. Mole weight: 4869.45.
Urotensin II (114-124), human
Urotensin II (human) is an endogenous peptide agonist for the urotensin-II receptor (EC50 = 0.1 nM). Urotensin II (human) increases calcium levels in a concentration-dependent manner in HEK293 cells expressing human UTR (EC50 = 0.6 nM), and causes arterio-selective vasoconstriction and vasodilatation in mammals in vitro and in vivo. CAS No. 251293-28-4. Molecular formula: C64H85N13O18S2. Mole weight: 1388.57.
Urotensin II (114-124), human acetate
Urotensin II (human) is an endogenous peptide agonist for the urotensin-II receptor (EC50 = 0.1 nM). Urotensin II (human) increases calcium levels in a concentration-dependent manner in HEK293 cells expressing human UTR (EC50 = 0.6 nM), and causes arterio-selective vasoconstriction and vasodilatation in mammals in vitro and in vivo. Synonyms: L-Valine, L-α-glutamyl-L-threonyl-L-prolyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (5?10)-disulfide acetate; Human UII acetate; Human urotensin II acetate; Urotensin II (human) acetate; H-Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH.CH3CO2H (Disulfide bridge: Cys5-Cys10); L-alpha-glutamyl-L-threonyl-L-prolyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-valine (5->10)-disulfide acetic acid. Grades: ≥95%. Molecular formula: C66H89N13O20S2. Mole weight: 1448.63.
Urotensin II (Gillichthys mirabilis) acetate
Urotensin II (Gillichthys mirabilis) acetate is a peptide ligand that is the strongest known vasoconstrictor. Synonyms: Urotensin II, mouse acetate; Gillichthys mirabilis urotensin II acetate; Urotensin II (Gillichthys mirabilis reduced), cyclic (6?11)-disulfide acetate; Urotensin II (goby) acetate; L-Valine, L-alanylglycyl-L-threonyl-L-alanyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (6?11)-disulfide acetate; H-Ala-Gly-Thr-Ala-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH.CH3CO2H (Disulfide bridge: Cys6-Cys11); L-alanyl-glycyl-L-threonyl-L-alanyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-valine (6->11)-disulfide acetate. Grades: ≥95%. Molecular formula: C64H88N14O19S2. Mole weight: 1421.61.
Urotensin II (goby) trifluoroacetate salt
Urotensin II is a potent peptide vasoconstrictor and an agonist of the urotensin (UT) receptor. For its distribution in multiple biological systems such as the cardiovascular, nervous, endocrine, and renal, it has been identified as a potential target for therapies of atherosclerosis, heart failure, hypertension, pre-eclampsia, diabetes, renal disease, as well as brain vascular lesions. Synonyms: U-II; Urotensin II (G. mirabilis). Grades: ≥95%. Molecular formula: C62H84N14O17S2·xCF3COOH. Mole weight: 1361.56.
Urotensin ii(human)
Urotensin ii(human). Uses: Designed for use in research and industrial production. Additional or Alternative Names: UROTENSIN-II;UROTENSIN II (HUMAN) HYDROCHLORIDE;UROTENSIN II (HUMAN);ETPDCFWKYCV, HCL (DISULFIDE BRIDGE: 5-10);GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL;GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL HYDROCHLORIDE;H-GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS. Product Category: Heterocyclic Organic Compound. CAS No. 251293-28-4. Molecular formula: C64H87N13O18S2. Mole weight: 1390.58. Product ID: ACM251293284. Alfa Chemistry ISO 9001:2015 Certified.
Urotensin II (human) trifluoroacetate salt
Urotensin II is a potent peptide vasoconstrictor and an agonist of the urotensin (UT) receptor. For its distribution in multiple biological systems such as the cardiovascular, nervous, endocrine, and renal, it has been identified as a potential target for therapies of atherosclerosis, heart failure, hypertension, pre-eclampsia, diabetes, renal disease, as well as brain vascular lesions. Synonyms: hU II. Grades: ≥95%. Molecular formula: C64H85N13O18S2·xCF3COOH. Mole weight: 1388.57.
Urotensin II, mouse acetate
Urotensin II, mouse acetate, a potent vasoconstrictor, is an endogenous ligand for the orphan GPR14 or SENR. Synonyms: L-Isoleucine, 5-oxo-L-prolyl-L-histidylglycyl-L-alanyl-L-alanyl-L-prolyl-L-α-glutamyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (8?13)-disulfide, acetate; H-Pyr-His-Gly-Ala-Ala-Pro-Glu-Cys-Phe-Trp-Lys-Tyr-Cys-Ile-OH.CH3CO2H (Disulfide bridge: Cys8-Cys13); L-pyroglutamyl-L-histidyl-glycyl-L-alanyl-L-alanyl-L-prolyl-L-alpha-glutamyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-isoleucine (8->13)-disulfide acetate; Urotensin II (mouse) acetate. Grades: ≥95%. Molecular formula: C78H104N18O21S2. Mole weight: 1693.92.
Urotensin II-related peptide
Urotensin II-related peptide is a human urotensin II anague. Urotensin II-related peptide has high affinity for the UT receptor [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 342878-90-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1165.
Urotensin I (white sucker) trifluoroacetate salt
Urotensin I is a naturally occurring peptide and a member of the corticotropin-releasing factor (CRF) family. It binds to recombinant human CRF1 and rat CRF2 receptors with Ki values of 0.7 and 22.9 nM, respectively. It has been shown to decrease blood pressure in the rat. Grades: ≥95%. Molecular formula: C210H340N62O67S2·xCF3COOH. Mole weight: 4869.46.
UR-PI376
This active molecular is a imidazolylpropylguanidine type compound as a hH4R agonist (histamine H4 receptor agonist) showing negligible hH1R and hH2R activities and high selectivity over the hH3R (pKB = 6.00, alpha = -0.28). Synonyms: UR-PI376, UR-PI-376, UR-PI 376, URPI376, URPI-376, URPI 376; 1-cyano-2-[4-(1H-imidazol-5-yl)butyl]-3-(2-phenylsulfanylethyl)guanidine. Grades: 98%. CAS No. 1192559-94-6. Molecular formula: C17H22N6S. Mole weight: 342.47.
Ursocholic acid
Ursocholic acid, a bile acid present in mammalian bile, is converted to deoxycholic acid (UDC) by the mouse intestinal flora. Ursocholic acid acts as a gallstone dissolving agent in the liver through anti- apoptosis , anti-inflammatory, immunomodulatory, bile regulation, and coordinated changes in mitochondrial integrity and cell signaling, Ursocholic acid also has favorable effects on bones in patients with chronic cholestasis [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 2955-27-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113212.
Ursocholic acid
Ursocholic acid. Group: Biochemicals. Alternative Names: (3a,5b,7b,12a)-3,7,12-Trihydroxycholan-24-oic acid; 3a,7b,12a-Trihydroxy-5b-cholanic acid; 3a,7b,12a-Trihydroxy-5b-cholan-24-oic acid. Grades: Highly Purified. CAS No. 2955-27-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C24H40O5. US Biological Life Sciences.
Worldwide
Ursocholic Acid
Ursocholic Acid. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Ursocholic acid, 3alpha,7beta,12alpha-Trihydroxy-5beta-cholanoic acid, 3alpha,7beta,12alpha-Trihydroxy-5beta-cholan-24-oic acid, 7beta-Hydroxyisocholic acid, 3alpha,7beta,12alpha-Trihydroxycholanic acid, 7-Epicholic acid, 3alpha,7beta,12alpha-Trihydroxy-5beta-cholanic acid,(3alpha,5beta,7beta,12alpha)-3,7,12-Trihydroxycholan-24-oic acid. CAS No. 2955-27-3. IUPAC Name: (4R)-4-[(3R,5S,7S,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid. Molecular formula: C24H40O5. Mole weight: 408.57. Catalog: APS2955273. SMILES: C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C. Format: Neat.
Ursodeoxycholic-1-methyl Ester (Ursodiol, 7b-Hydroxylithocholic Acid, Methyl Ester). Group: Biochemicals. Alternative Names: Ursodiol, 7b-Hydroxylithocholic Acid, Methyl Ester. Grades: Highly Purified. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Ursodeoxycholic-2,2,4,4-d4 acid 3-sulfate disodium salt
?98 atom % D, ?98%. Group: Fluorescence/luminescence spectroscopy.
Ursodeoxycholic-2,2,4,4-d4 acid solution
100 ?g/mL in methanol, ?98 atom % D, ?98% (CP). Group: Fluorescence/luminescence spectroscopy.
Ursodeoxycholic acid
500 ?g/mL in methanol, certified reference material. Group: Bile acid standards.
Ursodeoxycholic acid
Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 ( TGR5 , GPCR19 ) and the farnesoid X receptor ( FXR ). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection. Orally active [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Ursodeoxycholate; Ursodiol; UDCA. CAS No. 128-13-2. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-13771.
Ursodeoxycholic acid
Ursodeoxycholic acid (INN, BAN and AAN), also known as ursodiol (USAN) and the abbreviation UDCA, from the root-word for bear urso, as bear bile contains the substance, is one of the secondary bile acids, which are metabolic byproducts of intestinal bacteria. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tauroursodiol. Product Category: Steroidal Compounds. Appearance: Solid. CAS No. 128-13-2. Molecular formula: C24H40O4. Mole weight: 392.57. Purity: 0.98. IUPACName: (4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid. Canonical SMILES: CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C. Density: 0.9985 g/cm³. ECNumber: 204-879-3. Product ID: ACM128132. Alfa Chemistry ISO 9001:2015 Certified.
Ursodeoxycholic Acid. Group: Biochemicals. Alternative Names: UDCA; 3a,7a-Dihydroxy-5b-cholan-24-oic acid. Grades: Highly Purified. CAS No. 128-13-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C24H40O4. US Biological Life Sciences.
Worldwide
Ursodeoxycholic acid-2,2,4,4-d4
Ursodeoxycholic acid-2,2,4,4-d 4 is the deuterium labeled Ursodeoxycholic acid (HY-13771). Ursodeoxycholic acid is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection[1][2][3][4][5]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 347841-46-7. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-113478S.
Ursodeoxycholic acid acyl-b-D-glucuronide
Ursodeoxycholic acid acyl-b-D-glucuronide, an imperative compound in the field of biomedicine, serves as a remarkable treatment for cholestatic liver diseases. Derived from the esteemed ursodeoxycholic acid, it assumes the role of a hepatoprotective agent, substantially diminishing the build-up of pernicious bile acids within the hepatic system. Synonyms: URSODEOXYCHOLIC ACID ACYL-B-D-GLUCURONIDE; Ursodeoxycholic Acid Acyl-?-D-glucuronide, ~85%; (2S,3S,4S,5R,6S)-6-[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid; Ursodeoxycholic Acid Acyl-beta-D-glucuronide, >85per cent; W-201823. CAS No. 208038-28-2. Molecular formula: C30H48O10. Mole weight: 568.70.
Ursodeoxycholic Acid Acyl- β-D-glucuronide, >85%
A metabolite of Ursodeoxycholic acid. Contains products of acyl migration which were not individually quantified. Group: Biochemicals. Alternative Names: 1-[(3α,5 β,7 β)-3,7-Dhydroxycholan-24-oate- β-D-glucopyranuronic Acid. Grades: Highly Purified. CAS No. 208038-28-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ursodeoxycholic acid-D4
100 ?g/mL in methanol, certified reference material. Group: Bile acid standards.