A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
R1128 A is a non-steroidal estrogen-receptor antagonist produced by Streptomyces sp. No. 1128. The IC50 value of R1128 A for partially purified rat uterine cytosol receptor was 11 x 10(-7) M. Alternative Names: R1128A; R-1128A. CAS No. 135161-96-5. Molecular formula: C17H14O5. Mole weight: 298.29.
R1128 B
R1128 B is a non-steroidal estrogen-receptor antagonist produced by Streptomyces sp. No. 1128. The IC50 value of R1128 B for partially purified rat uterine cytosol receptor was 1.2 x 10(-7) M. Alternative Names: R1128B; R-1128B. CAS No. 135161-97-6. Molecular formula: C18H16O5. Mole weight: 312.3.
R1128 C
R1128 C is a non-steroidal estrogen-receptor antagonist produced by Streptomyces sp. No. 1128. The IC50 value of R1128 C for partially purified rat uterine cytosol receptor was 2.6 x 10(-7) M. Alternative Names: R1128C; R-1128C. CAS No. 135161-98-7. Molecular formula: C19H18O5. Mole weight: 326.3.
R1128 D
R1128 D is a non-steroidal estrogen-receptor antagonist produced by Streptomyces sp. No. 1128. The IC50 value of R1128 D for partially purified rat uterine cytosol receptor was 2.7 x 10(-7) M. Alternative Names: R1128D; R-1128D. CAS No. 135161-99-8. Molecular formula: C19H18O5. Mole weight: 326.3.
R)-(+)-1,1'-Bi-2-naphthol
25g Pack Size. Group: Building Blocks, Chiral Compounds, Ligands. Formula: C20H14O2. CAS No. 18531-94-7. Prepack ID 47008781-25g. Molecular Weight 286.32. See USA prepack pricing.
R)-(+)-1,1'-Bi-2-naphthol
5g Pack Size. Group: Building Blocks, Chiral Compounds, Ligands. Formula: C20H14O2. CAS No. 18531-94-7. Prepack ID 47008781-5g. Molecular Weight 286.32. See USA prepack pricing.
R121919
R121919 (NBI30775) is a potent and selective CRF1R antagonist with a Ki of 2 to 5 nM. R121919 has antidepressant and anxiolytic effects. R121919 alleviates defensive withdrawal in rats[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NBI30775. CAS No. 195055-03-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14127.
R)-1,2,4-Butanetriol
100mg Pack Size. Group: Building Blocks, Chiral Compounds, Organics. Formula: HOCH2CH2CH(OH)CH2OH. CAS No. 70005-88-8. Prepack ID 70324555-100mg. Molecular Weight 106.12. See USA prepack pricing.
R-(-)-1,2-Propanediol
R-(-)-1,2-Propanediol. Group: Biochemicals. Alternative Names: (-)-1,2-Propanediol; (-)-Propylene Glycol; (2R)-1,2-Propanediol; (R)-1,2-Propanediol; (R)-2-Hydroxy-1-propanol; (R)-Propylene Gycol; 1-Deoxy-sn-glycerol; D-(-)-Propanediol; NSC 90793. Grades: Highly Purified. CAS No. 4254-14-2. Pack Sizes: 10g. Molecular Formula: C3H8O2, Molecular Weight: 76.09. US Biological Life Sciences.
Worldwide
R-(-)-1,2-Propanediol
1g Pack Size. Group: Aroma Chemicals, Building Blocks, Chiral Compounds, Flavours and Fragrance Materials, Solvents. Formula: C3H8O2. CAS No. 4254-14-2. Prepack ID 26046346-1g. Molecular Weight 76.09. See USA prepack pricing.
R)-(+)-1,2-Propylene carbonate
1g Pack Size. Group: Building Blocks, Chiral Compounds, Organics. Formula: C4H6O3. CAS No. 16606-55-6. Prepack ID 24382572-1g. Molecular Weight 102.09. See USA prepack pricing.
R-130823
R-130823 is a ighly selective inhibition against mitogen-activated protein kinase p38alpha (IC50=22 nM). The release of tumor necrosis factor-alpha, interleukin-1beta, -6 and -8 was inhibited in lipopolysaccharide-stimulated human blood pretreated by R-130823 , with IC50 values of 0.089, 0.066, 0.95 and 0.16 microM, respectively. Category: Active pharmaceutical ingredients. CAS No. 321344-32-5. Product ID: API321344325. Molecular formula: C28H26FN3. Mole weight: 423.52.
R-1479
R-1479 (4'-Azidocytidine), a nucleoside analogue, is a specific inhibitor of RNA-dependent RNA polymerase (RdRp) of HCV. R-1479 inhibits HCV replication in the HCV subgenomic replicon system (IC50=1.28 μM)[1][2][3]. R-1479 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4'-Azidocytidine. CAS No. 478182-28-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10444.
R 1485 dihydrochloride
R 1485 dihydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
R162
R162 is a potent, selective inhibitor of glutamate dehydrogenase 1 (GDH1) (Ki = 28.6 μM), with anti-cancer properties. It does not inhibit the activity of other NADPH enzymes such as 6-phosphogluconate dehydrogenase and fumarate hydratase. Alternative Names: R 162; R-162; 2-allyl-1-hydroxy-anthraquinone; 2-allyl-1-hydroxyanthra-9,10-quinone. CAS No. 64302-87-0. Molecular formula: C17H12O3. Mole weight: 264.28.
R162
R162 is a potent inhibitor of glutamate dehydrogenase 1 (GDH1/GLUD1), with anti-cancer properties. Uses: Scientific research. Category: Signaling pathways. CAS No. 64302-87-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103096.
R176502
R176502 is a bafilolide metabolite with potent antiproliferative activity, which is produced by Micromonospora sp. JS1035. It inhibits proliferation of MCF-7, HT-29, K562/C1000 and Malme-3M cells with IC50 values of 1.29 ± 0.35, 0.61 ± 0.04, 9.29 ± 7.35, 7.96 ± 2.75 nmol/L. Alternative Names: R 176502. Molecular formula: C47H67NO13. Mole weight: 854.
R18
R18, a competitive inhibitor of 14-3-3 scaffolding proteins (KD ?80 nM), blocks the ability of 14.3.3 to bind to target proteins such as Raf-1, Bad, ASK1 and exoenzyme S. Alternative Names: R18; R 18; R-18; L-Prolyl-L-histidyl-L-cysteinyl-L-valyl-L-prolyl-L-arginyl-L-a-aspartyl-L-leucyl-L-seryl-L-tryptophyl-L-leucyl-L-a-aspartyl-L-leucyl-L-a-glutamyl-L-alanyl-L-asparaginyl-L-methionyl-L-cysteinyl-L-leucyl-L-proline trifluoroacetate; PHCVPRDLSWLDLEANMCLP trifluoroacetate; Pro-His-Cys-Val-Pro-Arg-Asp-Leu-Ser-Trp-Leu-Asp-Leu-Glu-Ala-Asn-Met-Cys-Leu-Pro trifluoroacetate. Grades: >98%. CAS No. 211364-78-2. Molecular formula: C101H157N27O29S3. Mole weight: 2309.69.
R1-ICR-5 is a highly selective RIPK1 PROTAC degrader. Mediated by VHL, R1-ICR-5 induces the degradation of RIPK1, which in turn dysregulates the TNFR1 and TLR3/4 signaling hubs, enhances the signaling outputs of NF-κB, MAPK and IFN, and simultaneously promotes RIPK3 activation and necroptosis (necroptosis). R1-ICR-5 can be used in the research of triple-negative breast cancer and skin inflammation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3070346-91-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-171658.
R-(-)-1-Indanol
R-(-)-1-Indanol. Group: Biochemicals. Grades: Highly Purified. CAS No. 697-64-3. Pack Sizes: 250mg, 500mg, 1g. US Biological Life Sciences.
Worldwide
R-1 methanandamide
R-1 methanandamide is a potent cannabinoid (CB) receptor 1 agonist with selectivity for CB1 over CB2 receptors with Ki values ranging from 17.9 to 28.3 and 815 to 868 nM, respectively. Alternative Names: (R)-methanandamide; R(+)-Methanandamide; R-(+)-methanandamide; AM-356; AM 356; AM356; (R)-(+)-Arachidonyl-1'-Hydroxy-2'-Propylamide. Grades: ≥98%. CAS No. 157182-49-5. Molecular formula: C23H39NO2. Mole weight: 361.6.
R-1 Methanandamide Phosphate
R-1 Methanandamide Phosphate is a water-soluble prodrug analog of arachidonylethanolamide (AEA). AEA is an endogenous cannabinoid compound[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 649569-33-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-126719.
5g Pack Size. Group: Building Blocks, Chiral Compounds, Organics. Formula: C6H10O3. CAS No. 15186-48-8. Prepack ID 64747409-5g. Molecular Weight 130.14. See USA prepack pricing.
R 268712
R 268712. Group: Biochemicals. Grades: Purified. CAS No. 879487-87-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
R-268712
R-268712 is an orally active and selective ALK-5 inhibitor, with an IC50 of 2.5 nM. R-268712 inhibits the phosphorylation of Smad3 in a dose-dependent manner with an IC50 of 10.4 nM. R-268712 suppresses glomerulonephritis as well as glomerulosclerosis by inhibiting TGF-β signaling, which can be used in studies of renal fibrosis and cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 879487-87-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12953.
R-(-)-2-Amino-1-butanol
5g Pack Size. Group: Building Blocks, Chiral Compounds, Organics. Formula: C4H11NO. CAS No. 5856-63-3. Prepack ID 24885258-5g. Molecular Weight 89.14. See USA prepack pricing.
R-2-(Aminomethyl)-1-BOC-pyrrolidine hydrochloride
R-2-(Aminomethyl)-1-BOC-pyrrolidine hydrochloride. Group: Biochemicals. Alternative Names: (R)-tert-Butyl 2- (aminomethyl) pyrrolidine-1-carboxylate hydrochloride. Grades: Highly Purified. CAS No. 1190890-12-0. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C10H20N2O2·HCl. US Biological Life Sciences.
1g Pack Size. Group: Building Blocks, Chiral Compounds, Organics. Formula: C4H10O. CAS No. 14898-79-4. Prepack ID 61686152-1g. Molecular Weight 74.12. See USA prepack pricing.
R(+)-2-Chloropropionic acid. Alternative Names: D-α-Chloropropionic acid. Grades: ≥ 98% (Assay). CAS No. 7474-5-7. Molecular formula: C3H5ClO2. Mole weight: 108.52.
R(+)-2-Chloropropionic acid 98+%
R(+)-2-Chloropropionic acid 98+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 7474-5-7. Pack Sizes: 1g, 5g, 25g, 100g, 250g. US Biological Life Sciences.
Worldwide
R)-(-)-2-Octanol
1g Pack Size. Group: Aroma Chemicals, Building Blocks, Flavours and Fragrance Materials. Formula: CH3(CH2)5CH(OH)CH3. CAS No. 5978-70-1. Prepack ID 17478884-1g. Molecular Weight 130.23. See USA prepack pricing.
R)-(-)-2-Phenylglycine
100g Pack Size. Group: Amino Acids, Biochemicals, Chiral Compounds. Formula: C8H9NO2. CAS No. 875-74-1. Prepack ID 35200423-100g. Molecular Weight 151.16. See USA prepack pricing.
R)-(-)-2-Phenylglycinol
5g Pack Size. Group: Amines, Building Blocks, Chiral Compounds. Formula: C8H11NO. CAS No. 56613-80-0. Prepack ID 90029563-5g. Molecular Weight 137.18. See USA prepack pricing.
R-30490 is a Fentanyl (F274990) analog. Fentanyl is used as an analgesic. Group: Biochemicals. Grades: Highly Purified. CAS No. 60618-49-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H32N2O2, Molecular Weight: 380.52. US Biological Life Sciences.
Worldwide
R-3,3,3-Trifluoro-2-hydroxypropionic acid
R-3,3,3-Trifluoro-2-hydroxypropionic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 121250-04-2. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
R-3930
R-3930.
R-(3)-Benzyloxy myristic acid
R-(3)-Benzyloxy myristic acid. Group: Biochemicals. Alternative Names: (R)-3-Benzyloxytetradecanoic acid; (3R) -3- (Phenylmethoxy) tetradecanoic acid. Grades: Highly Purified. CAS No. 87357-67-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C21H34O3. US Biological Life Sciences.
Worldwide
R-(3)-Benzyloxy myristic acid methyl ester
R-(3)-Benzyloxy myristic acid methyl ester. Group: Biochemicals. Alternative Names: (R)-3-Benzyloxytetradecanoic acid methyl ester; (3R) -3- (Phenylmethoxy) tetradecanoic acid methyl ester. Grades: Highly Purified. CAS No. 114264-01-6. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C22H36O3. US Biological Life Sciences.
R-(3)-Hydroxydecanoic acid methyl ester. Group: Biochemicals. Alternative Names: Methyl (R)-3-hydroxydecanoate; (R)-3-Hydroxy-decanoic acid methyl ester. Grades: Highly Purified. CAS No. 56618-58-7. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C11H22O3. US Biological Life Sciences.
Worldwide
R-(3)-Hydroxymyristic acid
(R)-3-Hydroxymyristic Acid is a component of bacterial Lipid A. It plays an intermediate role in fatty acid biosynthesis. Alternative Names: (R)-3-Hydroxytetradecanoic acid; D-(-)-beta-Hydroxymyristic acid; D-3-Hydroxyte. Grades: 95%. CAS No. 28715-21-1. Molecular formula: C14H28O3. Mole weight: 244.38.
R3 IGF-I
R3 IGF-I. Alternative Names: R3 IGF-I; INSULIN-LIKE GROWTH FACTOR I, R3,*RECOMB INANT. CAS No. 139659-92-0.
R-(-)-3-Quinuclidinol
R-(-)-3-Quinuclidinol. Group: Biochemicals. Alternative Names: (R)-(-)-3-Hydroxyquinuclidine; (R)-(-)-1-Azabicyclo[2.2.2]octan-3-ol. Grades: Highly Purified. CAS No. 25333-42-0. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C7H13NO. US Biological Life Sciences.
Worldwide
R-(-)-3-Quinuclininol HCl
R-(-)-3-Quinuclininol HCl. Group: Biochemicals. Grades: Highly Purified. CAS No. 42437-96-7. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
R406
R406 is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value. R406 reduces immune complex-mediated inflammation[1]. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM)[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 841290-81-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12067.
R406
R406(R406 besylate) is a potent Syk inhibitor with IC50 of 41 nM in cell-free assays, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. R406 induces apoptosis. Phase 1. Group: Inhibitors. Alternative Names: R406 besylate. CAS No. 841290-81-1. Pack Sizes: 5mg. Product ID: S2194. Formula: C22H23FN6O5.C6H6O3S. Smiles: CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)O. Storage Conditions: 2 years -80 in solvent.
United States; Europe
R406 Benzenesulfonate
R406 is a potent Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Alternative Names: R406; R 406; R-406. Grades: >98%. CAS No. 841290-81-1. Molecular formula: C28H29FN6O8S. Mole weight: 628.63.
R406 free base
R406 free base is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value. R406 free base reduces immune complex-mediated inflammation[1]. R406 free base also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM)[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 841290-80-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-11108.
R-4200
R-4200.
R)-(+)-4-Benzyl-2-oxazolidinone
5g Pack Size. Group: Amino Acids, Building Blocks, Organics. Formula: C10H11NO2. CAS No. 102029-44-7. Prepack ID 27204332-5g. Molecular Weight 177.2. See USA prepack pricing.
R)-4-Benzylthiazolidine-2-thione
1g Pack Size. Group: Building Blocks, Organics. Formula: C10H11NS2. CAS No. 110199-17-2. Prepack ID 90028106-1g. Molecular Weight 209.33. See USA prepack pricing.
R 50595
R 50595 is a selective non-competitive cisapride antagonist. Category: Active pharmaceutical ingredients. CAS No. 104860-61-9. Product ID: API104860619. Molecular formula: C30H35Cl2F2N3O3. Mole weight: 594.52.
R-(-)-5-(2A9mino-2-metnyl)Etnyl]-2-Metnoxy Benzene Suifonamide. CAS No. 112101-82-2. Product ID: ACM112101822. Alfa Chemistry - ISO 9001:32057 Certified.
R547
R547 is a potent, selective and orally active ATP-competitive CDK inhibitor, with Kis of 2 nM, 3 nM and 1 nM for CDK1/cyclin B, CDK2/cyclin E and CDK4/cyclin D1, respectively[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 741713-40-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10014.
R 568 is positive allosteric modulator and allosteric agonist of the human calcium-sensing receptor (hCaSR), increasing the sensitivity to activation by extracellular Ca2+. It dose-dependently decreases circulating levels of PTH in both normal individuals and patients with primary hyperparathyroidism in clinical trials. R-568 is used in research to explore novel actions of CaSR. Alternative Names: R 568 hydrochloride; R568 hydrochloride; R-568 hydrochloride; 2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanamine hydrochloride; 2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanamine Hydrochloride (9CI); (R)-2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanamine Hydrochloride; KRN 568; NPS-R 568; Norcalcin; R 568; R 568 (Pharmaceutical); Tecalcet Hydrochloride. Grades: ≥99% by HPLC. CAS No. 177172-49-5. Molecular formula: C18H22ClNO.HCl. Mole weight: 340.29.
R 568 hydrochloride
R 568 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 177172-49-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
R 59-022
R 59-022. Group: Biochemicals. Grades: Purified. CAS No. 93076-89-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
R 59-022
R 59-022 (DKGI-I) is a DGK inhibitor (IC50: 2.8 μM). R 59-022 inhibits the phosphorylation of OAG to OAPA. R 59-022 is a 5-HT Receptor antagonist, and activates protein kinase C (PKC). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DKGI-I; Diacylglycerol kinase inhibitor I. CAS No. 93076-89-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107613.
R 59-022
R 59-022 is a diacylglycerol (DAG) kinase inhibitor (IC50 = 2.8 μM) without affecting phosphodiesterase or phosphatidylinositol kinase, and potentiates the activity of protein kinase C by inhibiting diacylglycerol metabolism. R 59-022 also blocks vascular contraction induced by the thromboxane analog U-46619. At 10 μM, R 59-022 induces apoptosis in glioblastoma cells without being toxic to non-cancerous cells. Uses: Enzyme inhibitors. Alternative Names: R59022; R-59022; R 59022; 6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one; Diacylglycerol Kinase Inhibitor I. Grades: ≥98% by HPLC. CAS No. 93076-89-2. Molecular formula: C27H26FN3OS. Mole weight: 459.58.
R59949
R59949 is a pan diacylglycerol kinase (DGK) inhibitor with an IC50 of 300 nM. R59949 strongly inhibits the activity of type I DGK α and γ and moderately attenuates the activity of type II DGK θ and κ. R59949 activates protein kinase C (PKC) by enhancing the levels of the endogenous ligand diacyl glycerol[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 120166-69-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108355.